LOCUS       DAVLMQ010000001       114499 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000001 DAVLMQ010000000
VERSION     DAVLMQ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 114499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 114499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..114499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.001"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            112..294
                     /locus_tag="VXF95_000001"
     CDS             112..294
                     /locus_tag="VXF95_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1080618.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            304..669
                     /locus_tag="VXF95_000002"
     CDS             304..669
                     /locus_tag="VXF95_000002"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HEV1080619.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYYGDSAWEHLRAVTGI
                     DLLSILTDIANKKTGVKSK"
     gene            666..1855
                     /locus_tag="VXF95_000003"
                     /pseudo
     CDS             666..1855
                     /locus_tag="VXF95_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
     gene            complement(1931..3493)
                     /gene="guaA"
                     /locus_tag="VXF95_000004"
     CDS             complement(1931..3493)
                     /gene="guaA"
                     /locus_tag="VXF95_000004"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HEV1080620.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIREIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            3635..4333
                     /locus_tag="VXF95_000005"
     CDS             3635..4333
                     /locus_tag="VXF95_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1080621.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERRVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(4376..5272)
                     /locus_tag="VXF95_000006"
     CDS             complement(4376..5272)
                     /locus_tag="VXF95_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1080622.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLSYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSALTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQANIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAVFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(5281..6216)
                     /locus_tag="VXF95_000007"
     CDS             complement(5281..6216)
                     /locus_tag="VXF95_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HEV1080623.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYSGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGPVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQTFLEHYLADDFARDLNQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(6213..6938)
                     /locus_tag="VXF95_000008"
     CDS             complement(6213..6938)
                     /locus_tag="VXF95_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HEV1080624.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLASISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLGKDRNNVELWFEEV"
     gene            complement(7022..7657)
                     /locus_tag="VXF95_000009"
     CDS             complement(7022..7657)
                     /locus_tag="VXF95_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HEV1080625.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKMIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQDL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(7659..8486)
                     /locus_tag="VXF95_000010"
     CDS             complement(7659..8486)
                     /locus_tag="VXF95_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1080626.1"
                     /translation="MMIKIIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALAHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(8508..8843)
                     /locus_tag="VXF95_000011"
     CDS             complement(8508..8843)
                     /locus_tag="VXF95_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HEV1080627.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEGGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(8844..9560)
                     /locus_tag="VXF95_000012"
     CDS             complement(8844..9560)
                     /locus_tag="VXF95_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
                     /protein_id="HEV1080628.1"
                     /translation="MAHGDLLYHDGLFFSAKKEDGTYDFHENFEYVTPWLKQADLAIG
                     DFEGTINKDHYLAGYLLFNAPAEVMDAIKEAGYHVLDLAHNHILDSQIEGVISTADII
                     EKAGITPIGVYTHEQRDQAPLVIKEVNGIKVALLAYSYGFNGIEQYISQEDYNRYLLD
                     LNEDKMKAEVERAEKEADITIIMLQMGVEYRLEPTEEQKALYHKMIDWGADIIFGGHP
                     HVVEPSETVEKDGDKKLIIY"
     gene            10073..10684
                     /locus_tag="VXF95_000013"
     CDS             10073..10684
                     /locus_tag="VXF95_000013"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1080629.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            10729..11457
                     /gene="rlmB"
                     /locus_tag="VXF95_000014"
     CDS             10729..11457
                     /gene="rlmB"
                     /locus_tag="VXF95_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HEV1080630.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKNEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFRNRL"
     gene            complement(11496..12407)
                     /gene="trxB"
                     /locus_tag="VXF95_000015"
     CDS             complement(11496..12407)
                     /gene="trxB"
                     /locus_tag="VXF95_000015"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HEV1080631.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVREIKGENRVESVVFENVKT
                     GQVTEQVFGGVFIYVGLDPLGDFVKELNIQDQAGWIVTDNHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(12473..12697)
                     /locus_tag="VXF95_000016"
     CDS             complement(12473..12697)
                     /locus_tag="VXF95_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HEV1080632.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(12775..13518)
                     /locus_tag="VXF95_000017"
     CDS             complement(12775..13518)
                     /locus_tag="VXF95_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1080633.1"
                     /translation="MIKISNLSKSFSGQTVLDHLDLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(13518..14318)
                     /locus_tag="VXF95_000018"
     CDS             complement(13518..14318)
                     /locus_tag="VXF95_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1080634.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(14476..14832)
                     /locus_tag="VXF95_000019"
     CDS             complement(14476..14832)
                     /locus_tag="VXF95_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1080635.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(14826..15356)
                     /locus_tag="VXF95_000020"
     CDS             complement(14826..15356)
                     /locus_tag="VXF95_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HEV1080636.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDRNNRRRSTC"
     gene            complement(15356..15850)
                     /locus_tag="VXF95_000021"
     CDS             complement(15356..15850)
                     /locus_tag="VXF95_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1080637.1"
                     /translation="MEIRLAFPNEVDAIMQVMEDAKKCLADAGSDQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            15985..16431
                     /locus_tag="VXF95_000022"
     CDS             15985..16431
                     /locus_tag="VXF95_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HEV1080638.1"
                     /translation="MKTTFSYPKWAEIPNIDLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            16428..17075
                     /locus_tag="VXF95_000023"
     CDS             16428..17075
                     /locus_tag="VXF95_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HEV1080639.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(17096..17677)
                     /gene="pdxT"
                     /locus_tag="VXF95_000024"
     CDS             complement(17096..17677)
                     /gene="pdxT"
                     /locus_tag="VXF95_000024"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HEV1080640.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(17678..18553)
                     /gene="pdxS"
                     /locus_tag="VXF95_000025"
     CDS             complement(17678..18553)
                     /gene="pdxS"
                     /locus_tag="VXF95_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HEV1080641.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(18705..20084)
                     /locus_tag="VXF95_000026"
     CDS             complement(18705..20084)
                     /locus_tag="VXF95_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1080642.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAER"
     gene            20378..21301
                     /locus_tag="VXF95_000027"
     CDS             20378..21301
                     /locus_tag="VXF95_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HEV1080643.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            21361..21966
                     /locus_tag="VXF95_000028"
     CDS             21361..21966
                     /locus_tag="VXF95_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1080644.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFADKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEETDGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            21985..23229
                     /locus_tag="VXF95_000029"
     CDS             21985..23229
                     /locus_tag="VXF95_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1080645.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISVSLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGNADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(23345..23602)
                     /locus_tag="VXF95_000030"
     CDS             complement(23345..23602)
                     /locus_tag="VXF95_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002901318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HEV1080646.1"
                     /translation="MDPKKIARINELAKKKKTEGLTPEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEKGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(23644..25680)
                     /locus_tag="VXF95_000031"
     CDS             complement(23644..25680)
                     /locus_tag="VXF95_000031"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HEV1080647.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQSVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEDFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLILSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(25904..26821)
                     /gene="glyQ"
                     /locus_tag="VXF95_000032"
     CDS             complement(25904..26821)
                     /gene="glyQ"
                     /locus_tag="VXF95_000032"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HEV1080648.1"
                     /translation="MSKKLTFQEIILTLQRFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATSPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEMLLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRAKLLAEDAE"
     gene            complement(27015..27776)
                     /locus_tag="VXF95_000033"
     CDS             complement(27015..27776)
                     /locus_tag="VXF95_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1080649.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMAPDLAVWKELYLYQLMDYECSQQTQAI
                     ESHYHSLSENFLLQIVGHELAHWSEHFLDDFDGYDSYIWFEEGMVEYISRKYFLTEEE
                     FQAEKICNQSLVELFQKKYGWHSLNDFGSSTYDKNYASIFYEYWRSFLTVDKLVENLG
                     SVQAVLDSYHLWANTEKTFPLLDWFVQQKLIEKEI"
     gene            complement(28049..28891)
                     /locus_tag="VXF95_000034"
     CDS             complement(28049..28891)
                     /locus_tag="VXF95_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HEV1080650.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQDQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALAWSLAEGFLPLPKSITTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(29005..30396)
                     /locus_tag="VXF95_000035"
     CDS             complement(29005..30396)
                     /locus_tag="VXF95_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HEV1080651.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIEQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKYQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(30631..31008)
                     /locus_tag="VXF95_000036"
     CDS             complement(30631..31008)
                     /locus_tag="VXF95_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1080652.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKICQREGDTHQSYKHIAPV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            31241..32218
                     /locus_tag="VXF95_000037"
     CDS             31241..32218
                     /locus_tag="VXF95_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1080653.1"
                     /translation="MLKLGVIGTGAISHHFIEASHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLADKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFGKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYQTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            32215..33297
                     /locus_tag="VXF95_000038"
     CDS             32215..33297
                     /locus_tag="VXF95_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1080654.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSKT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLIYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILAVSLASDVNVKFRKVILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRMGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(33361..34407)
                     /locus_tag="VXF95_000039"
                     /pseudo
     CDS             complement(33361..34407)
                     /locus_tag="VXF95_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(34791..35987)
                     /gene="tuf"
                     /locus_tag="VXF95_000040"
     CDS             complement(34791..35987)
                     /gene="tuf"
                     /locus_tag="VXF95_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HEV1080655.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(36898..37767)
                     /locus_tag="VXF95_000041"
     CDS             complement(36898..37767)
                     /locus_tag="VXF95_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1080656.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(37991..38668)
                     /locus_tag="VXF95_000042"
     CDS             complement(37991..38668)
                     /locus_tag="VXF95_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1080657.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPIPEP
                     TPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLASLVLGFF
                     KKKEDEK"
     gene            complement(38626..39705)
                     /locus_tag="VXF95_000043"
     CDS             complement(38626..39705)
                     /locus_tag="VXF95_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HEV1080658.1"
                     /translation="MNIILIAKPLRENTNTKANALNNGWARSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVDSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDIVEPSRTVVEKIIPKLNIPEEEKKKKTSELAE
                     LISENVKVCYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNVTDKKLSSMT
                     TTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANYYKEGSQEKL
                     AESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPANAYQKTVQQ
                     LTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(39816..40070)
                     /locus_tag="VXF95_000044"
     CDS             complement(39816..40070)
                     /locus_tag="VXF95_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080659.1"
                     /translation="MLNVDQDFMSISKSNKSGSDWKKTFTVRTTNRLANDLNNVLKQA
                     DKDTPNTPIWLNSAASKAKDDDRAYKLLKTLIPGENYLSC"
     gene            complement(40410..40943)
                     /locus_tag="VXF95_000045"
     CDS             complement(40410..40943)
                     /locus_tag="VXF95_000045"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HEV1080660.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKNLPIVYIDETGIDRYLYRPYA
                     GAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(40930..41145)
                     /locus_tag="VXF95_000046"
     CDS             complement(40930..41145)
                     /locus_tag="VXF95_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1080661.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCAVPSVWAALKQIKVTLKKDDEL"
     gene            complement(41112..41255)
                     /locus_tag="VXF95_000047"
     CDS             complement(41112..41255)
                     /locus_tag="VXF95_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HEV1080662.1"
                     /translation="MAYSTDFKQRALDYIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            41489..43207
                     /locus_tag="VXF95_000048"
     CDS             41489..43207
                     /locus_tag="VXF95_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HEV1080663.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDIEYLKEVKDINI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPKEWNETAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            43318..43665
                     /locus_tag="VXF95_000049"
     CDS             43318..43665
                     /locus_tag="VXF95_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1080664.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     ADTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(43943..44779)
                     /locus_tag="VXF95_000050"
     CDS             complement(43943..44779)
                     /locus_tag="VXF95_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1080665.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTTLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(44792..45421)
                     /locus_tag="VXF95_000051"
     CDS             complement(44792..45421)
                     /locus_tag="VXF95_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1080666.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(45431..46072)
                     /locus_tag="VXF95_000052"
     CDS             complement(45431..46072)
                     /locus_tag="VXF95_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1080667.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(46218..47447)
                     /locus_tag="VXF95_000053"
     CDS             complement(46218..47447)
                     /locus_tag="VXF95_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1080668.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(47437..48603)
                     /locus_tag="VXF95_000054"
     CDS             complement(47437..48603)
                     /locus_tag="VXF95_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1080669.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            48747..49760
                     /locus_tag="VXF95_000055"
     CDS             48747..49760
                     /locus_tag="VXF95_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HEV1080670.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FERMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPDQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(49805..50224)
                     /locus_tag="VXF95_000056"
     CDS             complement(49805..50224)
                     /locus_tag="VXF95_000056"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HEV1080671.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(50235..51641)
                     /gene="atpD"
                     /locus_tag="VXF95_000057"
     CDS             complement(50235..51641)
                     /gene="atpD"
                     /locus_tag="VXF95_000057"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HEV1080672.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(51727..52605)
                     /locus_tag="VXF95_000058"
     CDS             complement(51727..52605)
                     /locus_tag="VXF95_000058"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HEV1080673.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(52621..54126)
                     /locus_tag="VXF95_000059"
     CDS             complement(52621..54126)
                     /locus_tag="VXF95_000059"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HEV1080674.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(54141..54677)
                     /locus_tag="VXF95_000060"
     CDS             complement(54141..54677)
                     /locus_tag="VXF95_000060"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HEV1080675.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(54677..55171)
                     /gene="atpF"
                     /locus_tag="VXF95_000061"
     CDS             complement(54677..55171)
                     /gene="atpF"
                     /locus_tag="VXF95_000061"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HEV1080676.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(55185..55901)
                     /gene="atpB"
                     /locus_tag="VXF95_000062"
     CDS             complement(55185..55901)
                     /gene="atpB"
                     /locus_tag="VXF95_000062"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HEV1080677.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLPYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(55936..56136)
                     /locus_tag="VXF95_000063"
     CDS             complement(55936..56136)
                     /locus_tag="VXF95_000063"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HEV1080678.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
     gene            complement(56211..57218)
                     /locus_tag="VXF95_000064"
     CDS             complement(56211..57218)
                     /locus_tag="VXF95_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1080679.1"
                     /translation="MQDNYTTKAKHLTIDSRRLIERWKKEGKSNREIASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSVTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLLYPRKGKALKKQASTNFKPAGQ
                     SIEQRSEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLFDVFSEEHIYYAHPYAFWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCLDYKSPREDFWMANLNLKFSKMEIIFIKRF
                     Q"
     gene            complement(57676..58074)
                     /locus_tag="VXF95_000065"
     CDS             complement(57676..58074)
                     /locus_tag="VXF95_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1080680.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
     gene            58202..58279
                     /locus_tag="VXF95_000066"
                     /pseudo
     CDS             58202..58279
                     /locus_tag="VXF95_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(58447..58929)
                     /gene="greA"
                     /locus_tag="VXF95_000067"
     CDS             complement(58447..58929)
                     /gene="greA"
                     /locus_tag="VXF95_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HEV1080681.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(59000..60655)
                     /gene="mltG"
                     /locus_tag="VXF95_000068"
     CDS             complement(59000..60655)
                     /gene="mltG"
                     /locus_tag="VXF95_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HEV1080682.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADESQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATEIVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQAVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTVNELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTNIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(60736..61230)
                     /locus_tag="VXF95_000069"
     CDS             complement(60736..61230)
                     /locus_tag="VXF95_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1080683.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(61227..61691)
                     /locus_tag="VXF95_000070"
     CDS             complement(61227..61691)
                     /locus_tag="VXF95_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1080684.1"
                     /translation="MEIPIKIIQASKFDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQCLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     ELDYKGIRLESPDELLSYFEMNGFVDEEETLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(61701..63035)
                     /locus_tag="VXF95_000071"
     CDS             complement(61701..63035)
                     /locus_tag="VXF95_000071"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HEV1080685.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLLRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFAGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(63046..63663)
                     /locus_tag="VXF95_000072"
     CDS             complement(63046..63663)
                     /locus_tag="VXF95_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1080686.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPITEEKPVKPIEKQVEKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(63711..66809)
                     /locus_tag="VXF95_000073"
     CDS             complement(63711..66809)
                     /locus_tag="VXF95_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1080687.1"
                     /translation="MAKLIPGKVRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDFFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLDRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVSDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQDIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPRQATQVQADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELPDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLTGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(66902..68068)
                     /locus_tag="VXF95_000074"
     CDS             complement(66902..68068)
                     /locus_tag="VXF95_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1080688.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEVQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDSLFEIDFDQLEKDLVEEE
                     VKLYVLCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVMDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(68076..69170)
                     /locus_tag="VXF95_000075"
     CDS             complement(68076..69170)
                     /locus_tag="VXF95_000075"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HEV1080689.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGHFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(69328..70770)
                     /locus_tag="VXF95_000076"
     CDS             complement(69328..70770)
                     /locus_tag="VXF95_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1080690.1"
                     /translation="MRKKVIEGLIYAEKSFFDKSQSGELTSAIVNDMSVIREFLITTF
                     PNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMMFIILPLSNISEKYSRRLQEEIG
                     FLTGQLTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSFETPFALLFI
                     FATIVVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTIYSSSKGSSVA
                     LENLLAVPKEKFEGGKSVSGQGLNFNHVYFGYDENRPVLKDITCSIFKGQKIAFVGPS
                     GSGKSTIVRLLERFYKPLSGDILMEQSSIYDFNLKEWRSKIAWVSQNNAVLSGSIRDN
                     LCLGLNRLVTDDELMKVLDLVSLGDEIRSMKEGLDTEVGERGRFLSGGQSQRLQIART
                     YLKDAEILIFDEATANLDADSEYAIISSLYSVLKEKTVVIIAHSLSTVKDVDCIFFLE
                     EGKITGSGTHKELLENHERYARFVQEQMIE"
     gene            complement(70776..71009)
                     /locus_tag="VXF95_000077"
     CDS             complement(70776..71009)
                     /locus_tag="VXF95_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HEV1080691.1"
                     /translation="MKLKLLRVDTKVIMWSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKR"
     gene            complement(71181..73142)
                     /locus_tag="VXF95_000078"
     CDS             complement(71181..73142)
                     /locus_tag="VXF95_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1080692.1"
                     /translation="MKKSKSKYLTLAGFVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGI
                     KALDDQTVQYTLARPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPANILYSGPFL
                     MKAFVSKSVIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQDALVRNFTDGAYSYARLYP
                     NSSSFEGIKEKYKDDIIYSMQDATSYYWNFNLDRQAYKFTSKTTDIEKKSTQEAVLNK
                     NFRQAINFAYDRTSYGAQTQGEDGATKILRNLVVPPTFVSIKGKDFGEVVASKMVNNY
                     GKEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDATVDQASKKGIQE
                     VSSMKQSIEAALGTENVVIDIQQLSTEDYDNSSYLAQTAIQKDYDLYNGGWSPDYLDP
                     STYLDIFSVKNGGVLQNLGLDPGEANDKAKAVGLDTYTQMLEEANKEQDPAKRYEKYA
                     DIQAWLIDSSLAIPNVSLGGTPSLRKTVPFSAPYSLAGNKGVESYKYLKVQDKIVTTD
                     EYAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            complement(73343..74965)
                     /locus_tag="VXF95_000079"
     CDS             complement(73343..74965)
                     /locus_tag="VXF95_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1080693.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            75071..76516
                     /locus_tag="VXF95_000080"
     CDS             75071..76516
                     /locus_tag="VXF95_000080"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HEV1080694.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVVFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVGIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKILAFTGTKGKTTAAYFAYNILSQRYPTALLSTMNTTLDGTTFFKSSFS
                     TPENIDLFDMMAQAVKNGRSHLVMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HPSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            complement(76562..76756)
                     /locus_tag="VXF95_000081"
     CDS             complement(76562..76756)
                     /locus_tag="VXF95_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1080695.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(76857..77465)
                     /locus_tag="VXF95_000082"
     CDS             complement(76857..77465)
                     /locus_tag="VXF95_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HEV1080696.1"
                     /translation="MFGELIRYLDQYEDVILREIKSQFPDVAVDKLMEEYIKASLILR
                     ENKRYYLNFPTLESLDSLELDQEIFVREASPVYQALLEQSFETELRNQINAAILVEKT
                     DFARIKMTLSNYFYKVKQQYPLTEKQQELYDILGDVNPEYALKYMTAFLLKFLKKDQL
                     MQKCRDIFVDSLVVLGYIVQNEDRKYELAIDFDKERLTFYLA"
     gene            complement(77490..78002)
                     /locus_tag="VXF95_000083"
     CDS             complement(77490..78002)
                     /locus_tag="VXF95_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HEV1080697.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAAFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERDLHDSDF"
     gene            complement(78089..79024)
                     /locus_tag="VXF95_000084"
     CDS             complement(78089..79024)
                     /locus_tag="VXF95_000084"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HEV1080698.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            complement(79095..79394)
                     /locus_tag="VXF95_000085"
     CDS             complement(79095..79394)
                     /locus_tag="VXF95_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HEV1080699.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            complement(79384..80133)
                     /locus_tag="VXF95_000086"
     CDS             complement(79384..80133)
                     /locus_tag="VXF95_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HEV1080700.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPHSNLNESEHYLLARHEITTNLEEICHSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            complement(80187..80546)
                     /locus_tag="VXF95_000087"
     CDS             complement(80187..80546)
                     /locus_tag="VXF95_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HEV1080701.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVVDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHYLKKKK"
     gene            complement(80548..81948)
                     /locus_tag="VXF95_000088"
     CDS             complement(80548..81948)
                     /locus_tag="VXF95_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HEV1080702.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIGKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGPLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            complement(82243..82482)
                     /locus_tag="VXF95_000089"
     CDS             complement(82243..82482)
                     /locus_tag="VXF95_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HEV1080703.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            complement(82514..82984)
                     /gene="ssbA"
                     /locus_tag="VXF95_000090"
     CDS             complement(82514..82984)
                     /gene="ssbA"
                     /locus_tag="VXF95_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HEV1080704.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            complement(82996..83286)
                     /locus_tag="VXF95_000091"
     CDS             complement(82996..83286)
                     /locus_tag="VXF95_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HEV1080705.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            complement(83439..84785)
                     /gene="asnS"
                     /locus_tag="VXF95_000092"
     CDS             complement(83439..84785)
                     /gene="asnS"
                     /locus_tag="VXF95_000092"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HEV1080706.1"
                     /translation="MMTKRVTIIDVKDYVGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            complement(84942..85166)
                     /locus_tag="VXF95_000093"
     CDS             complement(84942..85166)
                     /locus_tag="VXF95_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1080707.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKLAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEV"
     gene            complement(85159..86346)
                     /locus_tag="VXF95_000094"
     CDS             complement(85159..86346)
                     /locus_tag="VXF95_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1080708.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAVVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSAKEDNHFKVTVEQLEVA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEESEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            complement(86343..86831)
                     /locus_tag="VXF95_000095"
     CDS             complement(86343..86831)
                     /locus_tag="VXF95_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HEV1080709.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQVDQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            87152..87700
                     /locus_tag="VXF95_000096"
     CDS             87152..87700
                     /locus_tag="VXF95_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HEV1080710.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALASKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIQ"
     gene            complement(87937..93537)
                     /locus_tag="VXF95_000097"
     CDS             complement(87937..93537)
                     /locus_tag="VXF95_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HEV1080711.1"
                     /translation="MKHSHKKSFDWYSMQQRYSIRKYYFGAVSVLLGTALVLGAAASV
                     QTVQAEENKQETTNSISVGRGEAATKLAEVSASNKEKTYAAPTVANPVETTPVKTGEV
                     TKPAEKVEEAKDKKEEVTHQDAIDKSKLLTALSRAKKLESKLYTEASAANLQTSIQAG
                     QSLLGKADASEAELSAAESSIQSSIIGLELRSNSNKGTVSETPVAKKANIVEAKEETN
                     PAATTDRSAVDSAVLPTSTAAKVETTSAPASINEILKPGLSLSDARQNPAIRKEDLDK
                     GYSGFRAAPAPTNKLVTNLGNNTVFTDISRGSHTFRGNGNSRGGNPIHFDVTTTRVGN
                     RVEFSIAYSGPGEFVNNNFLLDKGNGFGEPSRATISTNRLRDQTKDIRKGANFVSHSS
                     YSLTSAVETNSNQTIRFSLPIANPNGDLSVRLRPVTFNVGQGESGSATSNDPYSNSNY
                     YFREKPLLLDANPNGGTNNKTVSEDIDFQTVYLPTSKLPEGQTRLVREGEKGQRQIIY
                     KVHQLGNETILGLPISNSVIKEVKPRIMQIGVAKDLIDTVKPRVDQNKVGDTNNLTFY
                     LDNDGNGVYTEGVDELVQKIAIKDGAKGEKGVQGERGLTGAQGQAGRDGVTPTVTVKD
                     NKNDGTHTITINDGRGNVASTVVRDGFDGASPLVATQRNEADKTTTVIFYYDQNGNNE
                     LDASDKKLKEVIIADGAKGEQGLQGRDGAQGPKGADGQRGPAGPQGPKGEQGNPGTPG
                     KDGKSLIAVKNGTETKVYVEDPARPGQPLNPNQPLATITDGRNGTNGQSPTITATRSV
                     QNGKNGVLVTITPVGGRPQTTFVEDGQKGADGKTPTVTITEGQNGTHTLTVHNPGSPD
                     VTTTIRDGATGQAGRDGKDVLNGKVNPQPNQGKNGDKYINTETGDVYVKNNGNWDKEG
                     NIKGPKGDKGADGAKGEKGDQGERGLTGAQGAKGADGAVGRDGRDGKDVLNGKANPEA
                     HQGKDGDKYVNTETGDVFVKNNGNWDKEGNIKGPKGDKGERGEDGKTPEVTVTPGKDG
                     HSTDITFTVPGKDPVTVNVKDGENGLNGKTPKVDLLRVQGKNGNPSHTIVTFYTDENN
                     DGKYTPGTDELLGSEMIKDGAKGADGRDGKSLLTVKDGKETKVYQEDPANPGQPLNPE
                     KPLAVIRDGVDGKSPTVTAVRKDEAGHKGVEITVDNHDGSQPTTVFVQDGAKGETGAT
                     GQDGQTPTITTQRGQDGQSTVVTITTSGKDPVTFTVKDGKNGKDGRAPKIKVEDITSP
                     SRIRRDTDAAATPTRNGIRVTVYDDVNDNGVYDGGVDKVLNSKDIYNGIDGRDGSAPT
                     ITTKDNGDGTHTITVQNPDGSESTTVVKDGKDGKTANITTTENPDGSHTITVTNPDGS
                     TKETVVKNGKDGKTPKVEVTDNNDGTHTVKVTDGDGNVTNAIIKDGKDGKAATATTTE
                     NPDGSHTVTITNPDGTKNEFVVKNGRDGVDGRTPTASVRDNGDGSHTIVITNPEGVTT
                     ETTVRDGKSPKVTITDEQNGTHKISVLNGDGTTTETIITDGKSPVATVRDNQDGTYTI
                     RVENGNGTVSETTVRDGKSPTAKVVDNGDGTHTITVVNSDGTTTTTTVRDGREPKLEV
                     IDNNDGSHTIKVTGADGKGTTTTIFDGKSPKANIVDNGDGTHTLTIVDSDGREYKSII
                     KDGKDGKDSVSPTVTVKNNNDGTHVVTITNPDGSKTEMVIKDGKDGKSPKVSVEDNGD
                     GSHTITIINSDGTVTKTVIKDGKDGRDGRDGRDGKDGKDGKCGCQDKPVTPSNDKPVP
                     PTPNVPTPEVPVKPVPAVPEQPVVPTPAQPATPVNANPVAPTTGKENRGDKLPETGSQ
                     SDYISVLLGSGILLSLYVGRRKED"
     gene            93753..95237
                     /locus_tag="VXF95_000098"
     CDS             93753..95237
                     /locus_tag="VXF95_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080712.1"
                     /translation="MRNLLSTKVQRQLRLMENLIQNRNWMKLHELAEKLGCTERILKS
                     DLNELRIAFPSINIQSSVNGIMIDLEVNTSVEDIYQYFLANSQSFQLLEYMFFNEGLP
                     IYRTIENLYFSSANLYRLGRNITKVLSSQFQIELSFTPSEIRGNEIDIRYFFAQYFSE
                     RYYFLDWPFPDLPEEDLTEFADFFYKITNYPMRFSIYRMYKLMIAISIHRVKNGHFID
                     LPNHFYKEYYPLLKSIPNFQETLAYFSKHFGLEMTPDTIAQIFISFLQNDIFLDPQEF
                     FNSLEDNSQARYSYQLLSQILERLSKQYKITFTNHDELIWHLHNTAFFERQEIFSTPI
                     LFEQKALTIKKFEVYFPDFMGSARQELAQYRQAIGQHDHPEQLEHLMYTILTHAENLS
                     TQLLENRPPIKVLIISNFDHAISLTFVDMLSYYCNNRFTFDIWDELKTSPEILNQTDY
                     DIIVSNFYIPGITKKFICRNHLSIINLVNHLNTLSNEIHLSNTL"
     gene            complement(95288..96016)
                     /gene="yaaA"
                     /locus_tag="VXF95_000099"
     CDS             complement(95288..96016)
                     /gene="yaaA"
                     /locus_tag="VXF95_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HEV1080713.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQTVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPALSPMAPHRLDFLMKLKVAGKTLKSHWKAVYDEALKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTFKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(96095..96259)
                     /locus_tag="VXF95_000100"
     CDS             complement(96095..96259)
                     /locus_tag="VXF95_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HEV1080714.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            complement(96325..97920)
                     /locus_tag="VXF95_000101"
     CDS             complement(96325..97920)
                     /locus_tag="VXF95_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080715.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESIKGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            complement(97932..98342)
                     /locus_tag="VXF95_000102"
     CDS             complement(97932..98342)
                     /locus_tag="VXF95_000102"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HEV1080716.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            complement(98458..99249)
                     /gene="yghU"
                     /locus_tag="VXF95_000103"
     CDS             complement(98458..99249)
                     /gene="yghU"
                     /locus_tag="VXF95_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HEV1080717.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            complement(99262..101958)
                     /locus_tag="VXF95_000104"
     CDS             complement(99262..101958)
                     /locus_tag="VXF95_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HEV1080718.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLAEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILVIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            102262..103446
                     /gene="mntE"
                     /locus_tag="VXF95_000105"
     CDS             102262..103446
                     /gene="mntE"
                     /locus_tag="VXF95_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HEV1080719.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLAAGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLEERF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            complement(103589..105460)
                     /locus_tag="VXF95_000106"
     CDS             complement(103589..105460)
                     /locus_tag="VXF95_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1080720.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTVLSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELDRAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELAWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTKGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKVEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(105457..106641)
                     /locus_tag="VXF95_000107"
     CDS             complement(105457..106641)
                     /locus_tag="VXF95_000107"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HEV1080721.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLEKISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSLLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            complement(106653..107420)
                     /locus_tag="VXF95_000108"
     CDS             complement(106653..107420)
                     /locus_tag="VXF95_000108"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HEV1080722.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLAGFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRAQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEVRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            complement(107697..108545)
                     /locus_tag="VXF95_000109"
     CDS             complement(107697..108545)
                     /locus_tag="VXF95_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1080723.1"
                     /translation="MKLAVFTDSSAYLSEETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            complement(108547..108921)
                     /locus_tag="VXF95_000110"
     CDS             complement(108547..108921)
                     /locus_tag="VXF95_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HEV1080724.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPSELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            complement(108995..110347)
                     /locus_tag="VXF95_000111"
     CDS             complement(108995..110347)
                     /locus_tag="VXF95_000111"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HEV1080725.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            complement(110371..111150)
                     /locus_tag="VXF95_000112"
     CDS             complement(110371..111150)
                     /locus_tag="VXF95_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HEV1080726.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            complement(111137..111994)
                     /locus_tag="VXF95_000113"
     CDS             complement(111137..111994)
                     /locus_tag="VXF95_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HEV1080727.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            112130..113098
                     /locus_tag="VXF95_000114"
     CDS             112130..113098
                     /locus_tag="VXF95_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1080728.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLNLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            complement(113351..114307)
                     /gene="lytA"
                     /locus_tag="VXF95_000115"
     CDS             complement(113351..114307)
                     /gene="lytA"
                     /locus_tag="VXF95_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1080729.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVLQVGPVNNGSWDVGGGWNAETYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKQDIENGLRAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWQKIADKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(114311..>114499)
                     /locus_tag="VXF95_000116"
     CDS             complement(114311..>114499)
                     /locus_tag="VXF95_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1080730.1"
                     /translation="NAVNAVEQVASETGFKGDEKLAQARAKVRAELTKYNISMTDKDL
                     DTFVESAVKQMNDAWKGR"
BASE COUNT        33366 a        25357 c        20980 g        34796 t
ORIGIN      
        1 ttatttataa caagaggata gaaatgaccg aattagaaag aaaaaatcga aaaattagct
       61 aagaaatatt ctgataactt aaacatcaaa gttcaagaga gagttcgtga aatggcaaat
      121 gataataaga gccattattt gatatacaga gttttaggta tttcatttga agaaggagaa
      181 aatatcgatt tgtatcaaaa taaaggtcgt tttttataca aatatgctgg ttcattttta
      241 gaagaagctg cagtactatc ctttaacgaa aaatttggta cagaaaatac ttaaaaagtt
      301 aacattccta attctgaaag tacaaaacct aagacttttg aaattgattg tttagtcgga
      361 gaaaaacacg catacgaaat aaaatggtgg gatgcaacta cagatggaga ccatataact
      421 aaagaacaca ctagaataaa agttattcat aacaaaggat atataccaat tcggttaatg
      481 ttctactatc caaatagaac tcaagctata aaaattcagc aaactttaga aacattgtat
      541 aacggtattg gagggaaata ttattatgga gattctgcct gggaacattt aagagcagtg
      601 accggtattg atttacttag tattctaaca gatattgcaa ataaaaaaac aggggtaaaa
      661 tcaaaatgac agtattaaaa ggagataact tagaaatatt aaaaactatt gaatcctcaa
      721 gtattgattt aatctatatg gaccctcctt tctttacaca gaaaacccaa aaattatcta
      781 ataacaaaaa tattatgtat tcattcgaag atacgtggac ttcgattgag gattacaaag
      841 aatttttgtc tgtaagatta gaagaatgca aaagagtgct aaaaaatagt ggcagtattt
      901 cgttcattgt gataaaattg caaatcatca tattagatta attttagata atatctttgg
      961 agcagatatg tttcaaagcg aaattatatg gaactataaa cgatggtcta attcaaaaaa
     1021 gggattattg aacaatcatc aaaacattta cttttattca aagtcaaaag attttaaatt
     1081 taatacaatt tttacagagt attcttctac tacaaatatc gaccaaatac tagtggaacg
     1141 aaaacgagat ggaaactcta aaactatata taaagttgat aataatggta actatattct
     1201 agcaaaagag aaaaatggag ttcccctttc agatgtttgg aatataccat ttcttaatcc
     1261 aaaagctaaa gaaagagtag gttatcctac acaaaaacct attctgttat tagaacaaat
     1321 tataaagatt gctactgata aaaatgatat agttttagac ccgttctgtg gaagtggaac
     1381 tactttagta gcctccaaga ttttgaatag aaattatatg gggattgatt tatctgagga
     1441 agctatcaat ataactcagc aacgtctgga aaatgttata aaaacaagtt caaatttatt
     1501 gaataaagga atcgaagcat atagaaccaa aactgaggaa gaggaaaaca ttcttaaatt
     1561 attacaggca aaaattgttc aaagaaataa aggaattgat ggttttttac ctaaacattt
     1621 tcaaaaaaaa ccgataccta taaaaattca aaaaaataat gaatgtctga atgagagtat
     1681 ctctttatta cagaatgcta taaactccaa aaaacttgat tttggagtag ttataaaaac
     1741 tcattcagat aatttattat ttgattttga tacgattcct gaaaatataa tagtagttga
     1801 ccattttgaa cttacaatcg aaaaatggtt aagtaaaagt caacagttac tatagtttgc
     1861 aaattattta cagaaagaac aaaaaatgct ctgaaacact gatttcaaag cattttttgt
     1921 tagtttaaaa ttactcccac tcaactgttg caggtggttt acttgtaata tcgtagacga
     1981 tacggttaac atgatccact tcatttacga tacgtactga gattttttga agtacttccc
     2041 atggaatttt ggcaaaatca gcagtcatac catcgataga agtgatagca cggattgcaa
     2101 tcgtgtagtc atacgtacga ccgtcaccca taacaccgac tgaacgaacg cctgtgttaa
     2161 cagtgaagta ttgccaaata tcgcggtcaa gtccagcttt agcgatttct tcacgaagaa
     2221 tagcgtctga ttcacgaacg gtttcaagtt tctcttcagt gatttcaccc atgacacgga
     2281 tagcaagtcc tggtcctggg aatggttggc gccatacgat atggtctggc ataccaagct
     2341 ctgtaccaag agcacgaact tcatccttgt aaagagtatt aagtggttca atcaattcaa
     2401 actgcatatc ttctggaaga ccacccacgt tgtggtgtga cttgatagtt tgagctgtat
     2461 ccgtaccaga ctcgataaca tctgtgtata aagtaccttg agcaaggaat ttcacatctt
     2521 tgagcttgct tgcttcgtca tcgaatacat agacaaactc gttaccgatg attttacgtt
     2581 tttgttcagg atcagaaacg ccagcaagtt tgtcaaggaa acgtttagca gcgtctgctt
     2641 tgacgatatt caaaccaaac ttaccaccga gcatgtccat aacttgatca gcttcgcctt
     2701 tacgaagaag accgtggtct acgaagatac agatcaattg atcgccaatc gctttttgga
     2761 gaagaacccc aacgacagat gagtcaacac cacctgatag accaagaagg acacgtttat
     2821 caccgacggt ttcacgaatt tttttgatct gcatgtcaat gaaattatcc attgaccagt
     2881 cacctttagc cttacaaatg ttaagggcaa agttacgaag gatatcattt ccgtatacag
     2941 aatgacgaac ttctgggtgg aattggatac cgtaaatgtg tttatctggg ttttcgatgg
     3001 ctgcgtatgg gcagtcagct gatgtacctg tacgaacaaa gtcagcagga atctcagtaa
     3061 ccgcatcacc atggctcatc aaaacagtct gttcatcagg tgttgattca aaaagcgctg
     3121 atggtgtgtg agttagggtt gattgaccgt attcacgatt tccagcatca cctgcaggaa
     3181 caacttttcc tccaagttta tgggtcaata actgcatacc ataacagatt cccaaaattg
     3241 gaattccgag ttcgaagatt tctgggtcaa tatcaaatga accatcttca tatacagaat
     3301 ttggaccacc tgatagaata attcctacag gattgacttc acgaacttca gcagctgaaa
     3361 ttttatggct ttttagttct gaaaaaacac caatctcacg gatacggcgt gaaatcagct
     3421 ggttgtactg gctaccatag tccaatacga tgattttttc tacatcttgc aaatcagttg
     3481 aaatgttgct catctttttc ctttctcaaa agaaatatct tttctcaata ttctatcaca
     3541 aataagggcg aattaccaac taaacaaggc gaagtttgac tttttctagt ttattggggt
     3601 acaatagaga aaagatagaa atgaagtgaa aaatatgcta cctgcttata tgaaaatcca
     3661 tgatcagata aaaaaggata ttgacgagca ccgttgggct attggtgaga ggcttcccag
     3721 tgaaagagat ttagctgagc agtttgcggt cagtcgcatg accctccgcc aagccgtatc
     3781 tctattagtc gaagaaggcg tcttagagcg ccgtgtagga agcggcacct ttgtttccag
     3841 tactcgagta caagaaaaga tgcgagggac aaccagtttt actgaaattg tcaaatccca
     3901 aggtaaagtt ccctctagcc agctcatttc ctacaaaaaa accattccca atgagcaaga
     3961 agttgccaag ctaggaattt ttccaacgga caatattatc cgaatggagc gggtccgcta
     4021 tgccgaccaa gttcccctag tttatgaagt tgcttctatt cctgaaaaat tcattaagga
     4081 ctttaaaaaa gaagaaatca ccagtcattt cttccaaacc ttgcagaaac atggctatcg
     4141 tatcggcaaa tctcaacaga ccatctatgc tcgccttgct aaagaaaaga ttgcccacta
     4201 tttggaagtt gaaaaaggac atgctattct tggattgaca caggtttcct acctagaaga
     4261 tggtactgct tttgaatacg taaaaagtca atatgtaggc gaacgctttg aattttatct
     4321 tgaaaataat tagattacca cgcaaaaact ctctgtcaca gacaaagagt cttttttatt
     4381 tttctaagaa taaatctttc aaagaaatca aagttacagc aaacaatatc attgccatac
     4441 caagaaaatc aatgggataa aattgttcat tcattattaa gaaggcaaag aaaaccgccg
     4501 atattggctc aattgaagcc aacaagcttg acttgaccgg tcctatcaga ctggctcctt
     4561 taaggaaagc tgtataggca aagacagtcc cgataaggat aatgcctgca aacgcaagga
     4621 gaaaatcaag actagtcggg atattggcct gtagaacccc tgtaaaagga agggcgacca
     4681 aacctgctat aaccattccc acaccaatga ccaagctact cccccacttt ttaatcaagg
     4741 ctatgggtaa aatgatatat agagcataag tcaaggcaga aaagagaccc cagaacaggc
     4801 cagcaggtgt catggataac tggtccaact gcccatgtgt tgcgatcagg aaggttcctc
     4861 cgatggcgaa tatgatggaa actatctctc ccagtgtcgg tgccacccta tccttgatac
     4921 agctataaat taaaattccg acaggacaaa catactgaag caccgtcgct gttcccgcat
     4981 tggtctcctg aatagcagac agataggcga attggttgag aaaaagacca atcagagcaa
     5041 aaataagaag agacagcaaa ctctttctat cctttaaaaa gaccagtatt ttatcctttg
     5101 cagtagcata agacaagagc atgagaattc caccagcgat taaaagacgc aagttggtca
     5161 agaccagagc cgaaattccg tgtgccatta ggtattggcc actcgttcct gacaaccccc
     5221 aagcaatacc agccacaact gttagtaaag tcccttttaa actatttgac atgtctctcc
     5281 ttactcttct ttgcgaatca agttcatcac ttgattgcgg tctaatatcc attgagctct
     5341 ctcgtccttt tcataggtac gattcgatag gaaaatagtg gcttcttgct tctgacgatt
     5401 ccacatgata aaggtacctg tatagcccgt atggtctagc caatctcctt ccaaattcca
     5461 tgctaaagaa cgttccttgt catccaaagg agaaaaattt tgatttaagt ctcttgcaaa
     5521 atcatctgct aaatagtgtt ctaaaaaggt ttgtaaatcc tttatagtcg aaaataaacc
     5581 agcactccca gcatgtctac ccaggagacg agccttggga tcatgcacta tgcctgcctc
     5641 tacacctcta actgttggaa cagcaagctc aactggccca aacttagttt ccgtcattcc
     5701 ccaaggtttc cagacttgat cctttaaaat cacatccaaa tcttgattaa aaattctttc
     5761 caaaataaag cccaacagca aaaaatggac atccgaataa agaaaggctg gctgacttcg
     5821 tctgttgaga tgaaacatcg cttcctttaa ttcaggggct gttaaaagat cacgattagg
     5881 aataaaagga tcaaggtctg ttgcatgagt caagagctgg cgaatagtga tgtctggata
     5941 atcactctca ggtaaaaaat ctattaccag tctatcaata tctaattgac ctatttccca
     6001 caagaaggta caaactgtgc caaccccaac aaccttactg acactagcta ggtcataaac
     6061 tagtcctgcc tcagtctgca agccatgctc tgggtcactc tggcctgaat agaactctgt
     6121 ccattgattg tccttaaaat acgcaaaaga ggctccggga taaatccctg cctcgatttg
     6181 ttcttctatt tttttaataa tcttggtcca cttcatactt cttcaaacca caattcaaca
     6241 ttatttctat ctttaccaag gaagaatttt tcagacttag gaataaaata ttcagtagac
     6301 tcaaacttct ggcgaagact tgctatgtct aattcattga ccaagaactt gagcatagat
     6361 aagtcccagg taaccgtatt gtccacagtc aaatcctgcc cctgagctgg aataaaatca
     6421 agggatgccc caatttcaga tgattccaag aaactttcga tatcagttgg gagatgtaat
     6481 tccatagaaa tctcaaattt acttaaagaa attgatgcca aatctgtttg aaattcaggc
     6541 ttttctccta cttctactag acttgctctg tcatcttccg catgaatcaa aatcaaatca
     6601 tcttctggtg agaaaatttc aaaagcgtag ccattttgac ctttatataa tcgatgaatc
     6661 gaatctgttt tagataagat tccttcaatt tctaagggat tttccacctt gacaatcaat
     6721 ctagctagtt tttttcttcc ctctacctta cgagtacgca tactgggagc ttcttctaaa
     6781 accagctttt caagacccgt ttggtcacct agtgacagaa aggccgattc ttctaacaag
     6841 gccttcattc caagggtttc aatataaaat gtttcattta attttctatt attagctttt
     6901 aaagtaggaa taatccgtac aatctgattt acattcataa attcctccgt cactttttat
     6961 tttaaaggat tttagaattt tttacaagat attatgctca aatttcacat tatttagcta
     7021 tttagtaaag atagtctttc aaggcttttg acaaagcctg ataaccagca atactgaggt
     7081 gcagtccatc agttgtatat tcttttttga gttggcctgc ttggtctgtc aaacaatcaa
     7141 atactggcac aaattccacc tgcatatagg cagatgcaag atcttgatag gcttgattcc
     7201 agttctgaat tttttcattc gagcggatat agactgcctg ctgatactcc tctccctcat
     7261 tgacaggtaa aatggaaagc aatttaatct ctgtcaatgg ataatcgcga gcaacggatt
     7321 gaatgatagc ttcgagatta ttgagagcct cattcacagg aacatccttt ccgatatcat
     7381 ttgtcccaat cagaagaaaa attttatcta ctgctccacc atatagatga gcatcaaggt
     7441 tctctagtaa cagtcctgtc tgatagccac gaattcctcg attgacaatc atttttgaag
     7501 tcccaaatag ctcctgtaga ggataatact cgacaatgga atccccaata aaaagaatgt
     7561 ttggttctac aacagaaatg tgatttaggt gacgatactt ggtttgaatt ttttcttgtt
     7621 cctttaggag ccaattttct aataactgta ctgccacttc attctccttt ttctaaccag
     7681 ttttccaaga cttgataaac tcctccttgg ctattggctg gtgctagagc agtcgccaca
     7741 gctttggctt tctcatcagc attttccatc gcataggcaa ttccagccat ttcaagcatt
     7801 tcaacatcat tttcactatc accaaaagcc atgatttctt gggatttcaa gtcccagcgc
     7861 ttgagtaatt cctccaagcc ccatgcttta tgaatcccag cttggaggat atcaatgcaa
     7921 ccatagccac tggatacagc tcggacacgg ccatcaaaga gagcattgat ttcttccaaa
     7981 accgaactca aacgttcctc accaacaacc atgctcatct tgagcacacc accaaagagg
     8041 tcagatgtta attcatccac aaattgcatc cgttggtaga atttttcaat catttctgga
     8101 gtcataaaac tttcaagatc tgtaaaaatc gtaccttcct tgacaaaatc acccttcatc
     8161 cccgttacaa caaactggtc ctgacacgct cgacccttga aatgagccaa agccttgttg
     8221 acaatggcgt catcccatgt ctgagcctga atcaattcat tgttttcaaa aatacgagcg
     8281 ccattagcaa caaccagaac cactcgatcc accaagggac tcagtagttg tctcatgcgg
     8341 tgaatttcat tgcccgtcgc aatgacaaaa cgaatgcccc tttgatccaa ctgatctaaa
     8401 atcttttcca atcgtgggag atcaagctga cctctagcat ccagcaaggt cccatccata
     8461 tctgtcgcaa ttatcttaat catcatttac tttcctctgg attcaagcta ataccacttc
     8521 aatcccacat gttcattcat ttctttatag gctgtatcaa ttcgttcctt agtcgcttca
     8581 tctaactggt cacgatgact gccaccctct ataaaatctt ccaaaatata agtttggtaa
     8641 tgatacaagg gatatccttc tggtgaaaag gttccctttg gtgttcgatt gacccaagta
     8701 ggatgagctt tagctgttcc gatagttgtt tttccatcct tcttcttgat ggtgacatcc
     8761 atgagaacac cacgttcagt ccacttagca ttctcttcat ctcccataga ttcaatccgt
     8821 tgattggaaa tgaagttccc catttaatag ataatgagtt tcttatctcc atctttttca
     8881 accgtttcag atggttcaac aacgtgagga tgccctccaa agataatatc cgctccccaa
     8941 tcgatcatct tgtgataaag agctttttgt tcttcagttg gttccaatcg atactcaaca
     9001 cccatctgaa gcatgataat ggtgatatct gcttccttct ctgcccgttc aacttcagcc
     9061 ttcatcttat cttcgtttaa atctaaaaga taacgattat agtcttcctg agaaatatac
     9121 tgctcaattc cattgaaacc ataggaatag gctaacaatg caaccttgat accattcact
     9181 tccttaatga ccagcggagc ctgatcacgt tgttcgtgcg tataaactcc gattggagtg
     9241 attccagctt tctcaataat atcggccgtt gaaataactc cctcaatttg cgaatccaaa
     9301 atatgattat gagctaaatc cagcacatga taacctgctt ccttaatagc atccataact
     9361 tcagcaggag cattaaagag aagataaccc gctaaataat gatccttatt aatggttcct
     9421 tcgaaatcac caatagctaa atctgcttgc ttgagccaag gagtcacata ctcaaaattt
     9481 tcatgaaagt cataggtacc gtcttctttt ttagctgaaa agaaaagtcc atcgtggtag
     9541 agcaaatccc cgtgggccat aattctggca gttttttcct cttcctactc ctgagacttt
     9601 tgcttagtcc cctcttgaga aatagtatct cgtttttgac tagtcaaggg attccttgga
     9661 agctttcaaa caacaagacc aagcccattg ataaaccaac tgctagcaag agtatcgcca
     9721 caaatccctt attgctccac ttgcgataac tcctaaaaag tttaccaagc ccttcataaa
     9781 acgaaaagct aaaccaccct gatttcgatt ttgtcttctt tgtatcttcg ttctccctac
     9841 tttcttatgc aagccttttc tttttattat atcacagata agtatttctt tcacaattga
     9901 attgaacttc ctatctattt tctataaatc ctaaatgcca taatgctttc aattcttgtc
     9961 attttgtgat atcatgtaga ggaaatgaac taatccacag tggcttattc caagtatacc
    10021 acttgggctt tggcagtagc taactgcact aaacataata taaggagaga aaatgtctgc
    10081 aatagaacgt attacaaaag ctgctcactt aattgatatg aacgatatta tccgtgaagg
    10141 gaatcctact ctacgcgcga ttgctgagga agtcactttc cccctatctg accaggaaat
    10201 catcctaggc gaaaagatga tgcaattcct taaacattcc caagatcctg tcatggctga
    10261 aaaaatggga ctccgcggtg gtgttggact ggctgctccc cagttagata tctcaaaacg
    10321 cattatcgct gttttggtac ctaatattgt tgaagaaggc gaaactccac aggaagccta
    10381 cgatttggaa gccattatgt acaatccaaa aatcgtctct cactctgttc aagatgctgc
    10441 tcttggcgaa ggagaaggtt gcctgtctgt tgaccgtaac gtgcctggct atgttgttcg
    10501 ccatgcccgc gttactgttg actactttga caaagatgga gaaaaacacc gtatcaaact
    10561 caaaggctac aactccattg ttgttcagca tgaaattgac cacattaacg gtatcatgtt
    10621 ttacgatcgc atcaatgaaa aagacccatt tgcagttaaa gatggtttac tgattcttga
    10681 ataaagaaaa tcccgttgca agacggggtt ttgtgttata atagaggcat gaaaacaaat
    10741 gatattgtct atggcgtcca cgccgttacc gaagccctcc ttgcaaatac aggaaacaaa
    10801 ctctacctcc aagaagatct ccgaggtaag aatgttgaga aagtcaagga actagctaca
    10861 gaaaagaagg tgtccatttc ttggacatca aaaaaatctc tctctgagat tactgaaggt
    10921 gctgttcatc aaggttttgt tctacgagtg tctgaatttg cctatagcga gctagattac
    10981 atccttgcaa aaacacgcca agaagaaaat ccacttctat tgattctaga tggtctaacc
    11041 gatccccata atctaggttc tatcttgcga acagccgatg cgaccaatgt ttcaggtgtc
    11101 atcattccca agcaccgtgc tgtcggagta actcctgtcg ttgccaaaac agccacaggt
    11161 gctattgaac acgttccaat tgcccgagtg accaacctca gtcaaacctt agataaactt
    11221 aagaatgaag gtttctggac ctttggaacg gatatgaacg gtactccttg ccacaagtgg
    11281 aatacaaaag ggaaaatcgc cctcatcatt ggaaatgaag gaaaaggtat ctctagcaac
    11341 ataaaaaaac aggtcgatga aatgattacc attccgatga atggacatgt tcaaagcctt
    11401 aatgccagtg ttgctgcggc cattctcatg tacgaagttt tccgaaatag actataaaaa
    11461 agtttccagt catctgattg gaaacttttt tatgattaac tatgttctgt aatgaattta
    11521 taggcttctt gaccagcgat agctccatct ccaaccgctg ttgttacttg gcgaaggtct
    11581 ttcaagcgaa catctccaac tgcaaagata ccgtcgactg cagttttcat gtggttatct
    11641 gtcacaatcc atcctgcctg atcttggata ttcaattctt taacaaaatc gccaagaggg
    11701 tccaatccaa catagataaa gacaccaccg aagacttgtt ctgtcacttg acctgttttc
    11761 acattttcaa atacgactga ttctactcgg ttttcaccct tgatttccct tactacagaa
    11821 tcccagataa agctgatttt ttcattcgca aaggcgcgat cttgtaaaac cttttgggca
    11881 cgaagttggt cacgacggtg aacaatggta acagtcttag caaaacgagt caagaagagg
    11941 gcttcttcaa cagctgaatc tccaccacca actaccaata aatcttggtc acggaagaaa
    12001 gcaccatcac acacagcaca gtaagaaaca ccacgactgt tcagttcttc ttctccaggt
    12061 actcccaaag gacggtgttt agaaccagtt gctacgataa ctgtacgtgt ttcatatgtt
    12121 tggtcatcag tcatcacttt cttaaaatca ccatggtctt cgacattttc aacataacca
    12181 taaatgtgct ccacaccaag attttcaagt ggttcaaaca tcttttcagc caattcaggt
    12241 ccactaatat tagcgtatcc tgggtaattt tcgatatcag atgtattatt catctgacca
    12301 cctggcagac caccttcaat caaagctact tttagattgc ttcgagcagc atacaaggcc
    12361 gcagtcatcc ctgcaggtcc agcaccgata ataatagtat cgtacatata gattccttct
    12421 ttcttgttgt aactatcttt attctaactc tttcttgtca atcacgcaag gattatgcct
    12481 tgaaaacaag aattaaactc ataaccgcaa aggataatac tgggacaacc aagactccaa
    12541 tcataatcat atcatagaga tgggcttggc gagccctggc tgtcttatca actcccgaca
    12601 tggctctcag accaatccaa atccctaaaa aaatcagaac aaggatggtg gtcaagatca
    12661 aactctcgaa atataaagaa aatagttgca gtagcatgat ttctctcatt tctatctttt
    12721 ttaaagagta aactcagcta gtccaactaa ctgagttttc ctttatctat tatatcaaat
    12781 ataagtccgt ttgtaactag cgaagaattc ttttgtccgc tcttctttag gggtgtggat
    12841 aatctcatcc ggtgttccag actcgatgat tttcccctta tctaagaaga gaatcttatc
    12901 agccacttgg gctacaaagg acatgtcatg actaaccaaa atcatggttt gacctgactt
    12961 agcagcatct gcaatagact tttctacttc accaaccaat tctgggtcaa gggctgaagt
    13021 tggttcgtct aagagcaaaa catctggttt catagcaagc gcacgcgcta gggcaacccg
    13081 ttgcttctgt ccacctgata aatggcgagg ataatggttt tcacggtccg aaagcccaac
    13141 cttagccaac tcttccttgg caatcttagt cgcttcttgg tcagataatt tcttgacaac
    13201 aaccaagcct tctttcacat tatcaagtgc tgttcggcgt tcaaacaaat taaactgttg
    13261 gaaaaccata gacaacttac gacgtagggc aaggatttct tcttgagtga ttttagaaaa
    13321 atcaactgaa aaaccatcaa tctgaataga gccactgtca ggtgtttcaa gataattgag
    13381 actgcgaaga aaggttgatt ttccagctcc tgaagaacca atcaaggcta caacttcccc
    13441 tttttgaata tccaagtcca gatgatccaa gacagtctgt cctgaaaagg atttgcttaa
    13501 atttgaaatc ttaatcatta acgaaggtct cctttcacat ctgtttgcac tgtatcaggt
    13561 gcagaaatag ccatttttct ctcgatgaaa cgaccgaggc tttcaattcc gatattgacc
    13621 acccaataaa caagggcaac ggagatgaag cgttcaaaat agcgataatc agctccacct
    13681 agaatctgag cttgggcaaa gacttccaca acacccgcac taaaagctag agatgttccc
    13741 ttggtcaaac cgatgaggga attaatcaag gttggagtag ctaccaccgc tgcattagga
    13801 ataatcactc gtcgataaac ttgcgctcgg gtcataccca gactgcgtgc cgcctcaatc
    13861 tcaccaggat taactgagag aatggctgca cgaatggttt cactagcata agctgcctca
    13921 ttaaaggcaa aggcgacaat cgcaaaagct gcagctggaa tcgcattgat attgagacca
    13981 gttccccatt gctgattgag ggctttcaaa gccaaaggga ttccgtagta ggtcaacatg
    14041 agttgcacca aaatcggtgt cccttttaag aaactaacaa agaaggcctg caagggatat
    14101 aaaatcttga cacgattgat cttcacaatg gcaaaaagaa gcgccaaaac caagccaaaa
    14161 agggcaccac caattgtcaa cataattgtt gttggaagtt gttggacaat tctagggatt
    14221 ccatcaaaga ccgaacgtag gctaaacagc ttgccatccg gaatcaattg catcaagttt
    14281 tggtaccaat ctgatgctaa aatcgttgta acattcataa aaacatcctc ttctgataat
    14341 gattcattct accatgcttc tgccgtcaat gaaattattt gctacggtca gatacagact
    14401 ttgtctacct actagtttat catactttga aacagggaag ttatatattt tatctatcaa
    14461 agagatagat aaaaactatt tcagtcccag ttcttcataa gattttcgat aaccgatttg
    14521 cttaacagtt ccattttcta ctaaaatagg ccgttttaac aacataccgt cacttgctag
    14581 caactcagcc gcttcttggt ttgacaaact tcctacctta tcttttagcc ctaattcacg
    14641 gtatttgata ccactggtgt tgaaaaattg cttcaattca aatcctgagg tttctagcca
    14701 attcaaaatg acttcttggc taggtgtttc ttccacgata tggacggctt tatagtccac
    14761 acctaattga tttaattctt gttttgcttt tttacaagtt gaacatttgg ggtattcgat
    14821 aaattctaac atgtgcttct ccttctattg tttctatctt taaaatctac tccttcatgc
    14881 tccaagagcc aagctttctt ttccactcct gcagcataac ctgtcagacg cttgcctgct
    14941 cccaacacac gatgacaagg tactaggata gaccaaggat tgcgtcccac tgctccacca
    15001 attgcttgag cagaagccac ttgcaggtct tgagcaattt gtccataggt cactgtctga
    15061 ccataaggaa tgccctgtaa atagtcccaa actctctttt caaaattcgt tccgattggc
    15121 gccaagagca agttggataa atcctgaggc ttgcctttaa agtaatcatc taagcaagca
    15181 ataactgggt ctaaaatagg atgactaaca acttcttcta tcgtttcatc tcctagtccc
    15241 ctctcaaaat gcttctgctc ctgaacccaa attccataca aataatggtc atcagctaca
    15301 agtgatagaa taccaattgg tgaggagtag aggattttta catacttctt ttgcattatt
    15361 tctttaattt ttgataggcc aagcgttcgc catctactgg caccttacca acttgtttaa
    15421 aaccaagttt ttcaaaaata tgttgcataa ccttgttttc agcatgcgta tctgagcgaa
    15481 aatcaagata atcaaaacct tcaatcaagc cctctaagaa ggtttgagca actccttttc
    15541 cctgcacatc tgctgccaca gcaatacggt gaaagactag atactctgac tctcccgctt
    15601 gccagtttcc ctcataaata gcttcatagg cctcctctgg actcttggtc acagcagcat
    15661 aggctagcag ttctccctct tccaaggcta cgtaggcttg ccctgagatg atatcatcga
    15721 taataacatc tgcatttgga tagccatttt gccactggtc actaccagca tctgctaaac
    15781 attttttggc atcctccatc acctgcatga tggcatctac ttcatttgga aaagctaaac
    15841 gaatttccat cttttttcct catttctgac tagtttctcc catcatagca taatttaagt
    15901 atttctacaa gcagttaaaa cttgactttg tgtttttgtt attttataat ctagttatca
    15961 aaactatata aaaaggagtt gaaaatgaaa actacctttt cctacccaaa atgggcagaa
    16021 attccaaaca ttgacctcta tctggaccag gttttgctct atgtcaatca ggtctgcgcc
    16081 cctatctctc ctaataaaga caagggccta acagcatcta tggtcaacaa ttatgtgaaa
    16141 aatggttacc tgacaaagcc tgacaaaaaa aaataccaac gccaacagat tgcccgtttg
    16201 attgctatca caaccctcaa gtctgtattt tctattcaag aaatagccca gacacttaat
    16261 actctacaaa ctcaagcaag ttcagaccaa ctctacgatg cttttgtgga ctacatgaac
    16321 caaggaattg acccagctaa ccctattatc caaaccagct gccaaaccgt taaactctat
    16381 catcaaactc tagacttaat cgatcatact caagaggagg taatccaatg aacactagtc
    16441 ttaaactcag caaacaactc agttttggag aggagattgc taatagcgtg acccatgctg
    16501 tgggtgcagt catcatgctt atcttgctgc ctatttcatc catctatagt tatgaagcac
    16561 acggattttt atcctctatc ggcgtttcca ttttcgtcat cagtctcttt ctcatgttcc
    16621 tatcatccac catttatcac tctatggcct atggttcgac ccacaaatat gttttgcgaa
    16681 tcattgacca ttctatgatt tacgttgcca ttgccggctc atacacgccc gttgtcttga
    16741 ccttgatgaa taactggttt ggctatctga ttattgtcat ccaatgggga acgaccatct
    16801 ttggtattct ctataaaatc tttgctaaaa aggtcaatga gaaatttagc cttgctcttt
    16861 atctgattat gggctggttg gttctggcta tcattcctgc cattatcagt caaacgacac
    16921 ccgttttctg gagtctcatg gtaactggcg gactctgtta tacagttgga gctggatttt
    16981 atgccaagaa aaaaccttat ttccacatga tttggcatct ctttatccta gctgcgtccg
    17041 cacttcaata catcgctatt gtttattaca tgtaaaaaag ttgagaaatt caatctcaac
    17101 ttttttcttt acacatattg ataaagtact ggtgcaagcg cacatcatca gtcaattctg
    17161 gatgaaaaga acttaccaac atattttttt cttgggctgc aacaatttga ttgttcactg
    17221 ttgctagaat ttctacaccc tcaccaacac tactgataat cggaccacgg ataaaggtca
    17281 ttggaatctt gccaactccc ttacattctg cttccgtgta gaaacttcct aattggcgcc
    17341 cataagcatt acgctcgacc accatatcca tagttcctag atgactctct ttctgagaag
    17401 tgatttcctt agccagcaaa attaagcccg cacaggtccc aaacactggt aagccagata
    17461 gaatggcttc tcggatggga agtagcatgt tctggtcacg taagagcttg cccatggttg
    17521 tagactcacc accaggcaaa atcaaacccg acaagtcact ctgatcttgc tgaaaatcat
    17581 ctagatttct gagttctaca ctctcgacac ctaattgatc tagcactttt gcatgttctg
    17641 caaaggcccc ttgcaaggcc aatattccga ttttcatcta ttttcctcgt tcagccatga
    17701 gaatttggat ttcattttca ttaataccaa ccatggcttc tcctaaatct tcagagattt
    17761 gagctaggat ttgaggatta cggaagttag tcacagcctt aacaatggca ctcgctcgtt
    17821 taacaggatc tcctgacttg aaaatacctg aaccgacaaa gaccccctct gcccctaatt
    17881 gcatcattaa cgcagcatct gctggcgttg caacacctcc agcagcgaaa tttacaactg
    17941 gcaattttcc atgttcatga acatattgga ccaattctac agggacttgc aaatccttgg
    18001 cagcaacata aagctcgtcc tcacgtaagt tttgaatgcg gcgaatttcc tgattcatca
    18061 tacgcatatg acgaacagct tggacgatat cccctgtccc tggttctcct ttggtacgaa
    18121 tcatggaagc accttcagcg atacgacgca aggcttcacc caaatcctta gcaccacaga
    18181 caaaaggaac ttggaattct ttcttgtcca catggaaacg gtcatcagct ggagatagaa
    18241 cttcactctc gtcgatataa tcaatttcaa tagcctctaa aatctgagct tcaacaaaat
    18301 gcccgattct gaccttagcc attactggaa tactaaccgc ttcttggatt tccttaatca
    18361 tctttgggtc gctcatgcgg gaaactcctc cagctgcacg aatatcagcc ggaattcgtt
    18421 ccaaggccat cacagctgcc gcaccagcag cttctgcgat acgagcctgt tcaggattct
    18481 gcacatccat aataacacca cccttgagca tctgtgccaa gtttttattt agttcataac
    18541 gattttcagt catttgtttt atcctcatca tttgtattgg tagctacctt ttcattttaa
    18601 gtcagaacag aatgaagcac aagataaaaa aactataatt gtatggggac agattggcta
    18661 aaaactatct gaccttaact taaggccaga tagctcattc atttttatct ttcagccgta
    18721 agggcagcca ttgtgatgta gttgtatggt ttattgaagt gtggcaagaa gaagaggtct
    18781 gtcaatgcca atttatcaat tgtcacatgc tcttggatag caagtgagaa catgtggatt
    18841 cccatgctaa ttgcaatatc atgtgaaacc atttgggcac caagaatttc acggctatct
    18901 ttgtcaaaga caatcttaat tgctacttca tggttgtcat gtttcatgaa ttctggtttt
    18961 tgaagatcgt taaagcctgt ttcagttgcg ttgtaaccag cagctttcgc tttttcaaga
    19021 gtcaaaccag ttgaaaccat gtgaagaccg tagattgaga taccatttga accttgaaca
    19081 ccgattcctt ccaattcatg tccacaagcg ttgtaggcac caacgatacc agtgcgaaca
    19141 gcatttgaag caagagcgat atagcttgta tctttacgag cattgtcata aacagtcgca
    19201 cagtcaccaa cagcgtaaac gcctgggata gatgtttctt gtttcttgtc tacaaggaag
    19261 gcaccgttgc ggaagagttc gatcttacca tctgcaaggg ctgtgtttgg acggaaacca
    19321 actgcaagga taaccatatc cacgtcaaag ctttctttgt cagtaatcaa gcgttcaact
    19381 ttaccgtcac cttcgattgc tttaacagtt tgacctagag ccaagcggat gttgtgatct
    19441 tccaagttct tcgccatcat ttgtgtgaag tctttgtcat agtaaccgtt caagacagta
    19501 tcaacgatat caacaaggac aacttctttt ccaagacgtt caaaggcttc agcaagttca
    19561 acaccgatgt aaccaccacc aacaacggcg atacggtcga ggtgttggct cttgtcagaa
    19621 agtttattga taacttcttc agcattttgg tacaatttca cgaattgtac gttttcaaga
    19681 gttgctttaa attcgcggtt tcctttaaca atttcaacac cttcgattgg tggcaagatt
    19741 ggtgtagaac ctgtagcgaa aatcaatttt tcgtatgatt ctttgtgctc ttttccttca
    19801 acttccgctg taactacttt gttatcatag tcgattgaaa gaacaggtga gttcatgtaa
    19861 actttagcac ctttagcttc caatttttct ttatcagaat agaacaagcc ttcagcaccg
    19921 tcaatttgtt caccaatcca aagagccatt ccacatccta ggaaagagat gttagagttt
    19981 tggtcaaata caacaatttc gttctcattt ccaaaattat ccaacatggt attgatacat
    20041 gctgtaccag cgtggttagc accgactaca acgattttac tcataaaaat ttcctgcctt
    20101 cattctaaat ttaccttact agtataccat ttaccgttag cgtttacaag gggggtacta
    20161 ttatttcagc attttttatc aaaaataatt ccccatttat cctgttttca agcctcatga
    20221 attttatgag catatttctt gactttttcc aaattttgtt tgtgaaaatt ctaactttat
    20281 ggtattataa taacatgaaa atgaaatgta agggcttcaa tttagatgat tatttgatat
    20341 tacaacttat tttctataag agaaaggagt tggtagcttg actcttcgtt cacattctga
    20401 acggctaatg gggactacta tcactatttc attagtggat gagcaagccg atatctttct
    20461 ccaaaaatcc tttgacttgc tcaaagaact tgaataccgc ttcaacgcca atagtcaaga
    20521 atctgagttg atggaaatca attatcaagc aggaatagcc cccgtcacgg ttcatccaga
    20581 cctgtttgag ctgatttcac ttgggttaga gcatagccta gcgctctcta gccacctcaa
    20641 tatcagcatt ggtcccttaa ttcaaacctg gcgtatcggt ttttcagatg ccaaggtcgc
    20701 ccagcctcaa gaaattgaat cggtgctgcc tctaatcaat cctcatggta tcgagttaga
    20761 ttcttctact tctactgtgt ttttaaaaca gaaaggaatg aagatcgatc taggttgttt
    20821 agccaaagga tacagtgcgg ataaggttgc ccaatttctt aggaaagagg gggtgacttc
    20881 tgccttgatc aatctgggag ggaatatcct gaccattgga aaaaatcagg caagagggga
    20941 taacccatgg caaatcggga ttcaagaccc agccaatcct aggggaaatc atttaatgac
    21001 catccctgtt gtcaataaat ctgtcgtgac ttcaggcatt tatgaacgtc acctgaccgt
    21061 cgatggacaa gattaccatc acatttttga cagtcaaaca ggatatcctg ttgaaacgga
    21121 actagcgagt ctaacaatca tctctgataa atcagtcgat ggcgaaatct ggacgactcg
    21181 actctttgga gaaagacctg cttctatcct ctggcaagtc gaaagtttgg agggcatcga
    21241 agtcatcctc atcgataaag aaggccacct aagctgttct tcaggaattc ctactctata
    21301 gagacaactg tttcaatgga attttaaaat tgtattatgt aaaaagagaa aggaaatctc
    21361 atgttaaaac ttattgctat tgttggaaca aattcaaaac gttctacaaa ccgtcaattg
    21421 cttcaataca tgcaaaaaca ctttgctgac aaagctgaaa ttgagcttgt tgaaatcaag
    21481 gccattcctg tcttcaacaa accagctgac aagcaagtac ctgctgaaat attggaaatt
    21541 gctgctaaaa tcgaagagac agatggcgtt attatcggta ctcctgagta tgatcactct
    21601 attccagctg ttttgatgag cgctcttgct tggttgtctt atggtattta cccacttttg
    21661 aacaaaccaa tcatgattac aggtgcttct tacggtacgc ttggttcatc tcgtgcccaa
    21721 ttgcaacttc gtcaaatctt gaatgctcct gaaatcaagg caaatgttct tccagatgaa
    21781 ttcttgctct cacactctct tcaagcattt aacccaagtg gcgacttggt tgaccttgat
    21841 gttatcaaga aattggatgc catctttgat gacttccgta tctttgtaaa aatcacagaa
    21901 aaattacgta atgcacaaga attacttcgc aaagatgctg aagactttga ctgggaaaat
    21961 ttgtaagata ggagaccaaa aagaatgaaa tttgttggac ttgttggatc aaactacgat
    22021 caatcatata accgtaagct cttggaattt atccgtcgct acttcaaact caaatttgaa
    22081 ttagaagttc ttgaaattga cgaagttcca atgtttaacc aagatgaaaa atgggatgaa
    22141 agtttccaat tacgttattt atataacaaa attactcgtg cagatggtgt tatcattgct
    22201 actcctgagc ataaccacac tatctcagtt tcactcaaat ctgtacttga atggctttca
    22261 tacgaagttc atccatttga aaacaagcct gttatgattg tgggtgcatc atactatgac
    22321 caaggaacat cacgtgctca agttcacctt cgtaaaatcc ttgatgctcc aggtgttaat
    22381 gcctacacgc ttccaggtaa cgaattcctt cttggtaaag ctaaggaagc ttttgataac
    22441 aacggaaata tcaccaacga aggcactgtt aaattccttg aaacttgctt agataacttt
    22501 gttaaatacg taggagtcgt ttcgaaattg aaaaaaccaa aaccaatcga atcagaagac
    22561 ttggattgtg gaaaaccaat cgctacaacc atcacagaag ttgaccctga cgatccagaa
    22621 tgggtagaaa aagttgcagc aatcactggt gctgtttctg gtgataccta tgtcaaattg
    22681 gaccacggta tcctaacagt taaccaaatt gatatgttct tgaaagctat gccatttgaa
    22741 ttgacatacg ctgacgacaa caaccaattc ctctactaca acaacgctca ccaagatcca
    22801 gacactatgt tcgctaaacg tgtaccacct caatcaggta gccgtatgtc gactgttcat
    22861 ggttctcttc caccagcacg tatgaagaac gtagagtggg ttatcggaac acttcgcaac
    22921 ggaaaccaag aatacgtccg tacgatcgtt ccaggttctc ctgcaggtgt tatcaacact
    22981 cacaactacc aagcaatgta ctatcctgat ggatcatacg ctggtatcaa tgaaatcgtc
    23041 tttaacttcc aaccatggct tgactggtac ctaaaagaga ctggtcaacg tttggtgggt
    23101 ggtagcggac catttgctcc tgctgccgga ggtcatggaa acgccgatgc tacttctggc
    23161 gcttctgatt caggggatgc tggaggccac ggtggtgacg cagatgctac agccggtgca
    23221 agttactaat gatagttttt aggaaccatt atggttcctt ttttagcgaa aaaagactag
    23281 caaacacaaa ctgctagtct ctttgttatc gtttcatcta tctttgttaa aagaaaaata
    23341 catattatga atttgggtca tcaagactac ggccatgtaa tcctttttca cgttgtactt
    23401 ggcgtagttt ttctggtgta acatcgtttc ctttttcgtc cacaattttg attccttcaa
    23461 tgtgatgacg aacagcgcga cgataacctt cgatgtactc ctcacgtagt ttggcttgtt
    23521 ccactttttc ttctggtgtt aagccttctg tttttttctt tttagcaagc tcattgatac
    23581 gagcaatttt tttcggatcc atttcttctc ctctgtaata agataaagtc cgtttatcaa
    23641 attttattta gtgttaattt ggttaaaaca agcaaactta gctgctttct tggttagttg
    23701 tgacaagatt gccaaacgat tttgacggac agcctgatct tcagccatta ccatagtatt
    23761 ttcaaagaaa gcatcaatga ctgggctaag cgcaaaaagt tgtttcaatt gctgacttgc
    23821 aggtcctgat aaaatgagtg tttctactgc ttctgccaaa gctttttctt ggtcattctc
    23881 aaatagtgct gaatcaaccg tagcaacccc ttctgccttc tcagccaggt taaaggcacg
    23941 agaaagtgat tcaacagatg gtttaaaatc ttcttccttg cttacttcta cgagagcact
    24001 tgctgcttcc aacatatctg ccacaacaaa gtttgaacct gcaagaactg cttccttgat
    24061 atcttttgga gtagagccca tcatcttatc aacacgagcc ttgataaagt ccataacctc
    24121 tgctttattt tcataagtca aactgtcaaa tttcaatgca taaaggctat caatcagctc
    24181 atccatagca atgtgccaac caaaggcatc caagatacga accacacctt gagttgcacg
    24241 acgaagggca taagggtcat tagaacctga tggaatcaat cctactgaga agaaactcaa
    24301 aatcgtatcc aatttgtctg caatggctag aactgcaccg accttgctct ctggaagttc
    24361 tccttcagct gatgtaggca tgtagtgttc acgaatagca gctgccaccg ctggagtttc
    24421 accagcaaga agggtgtatt tttcacccat aattccttgg agttcgtcaa attcaccaac
    24481 catacctgtc aacaagtcaa acttgtaaat ggctgctgca cgagcaaggt caactgtttc
    24541 atccactgac aaaccagctt tttctgccaa aagtacagtg atttgacccg tacgaatcat
    24601 gtgttcacga agggaaccaa tcttctcatg gaaggtaaca ttgtttaatt tttcaacaag
    24661 atctgaaatc accaattttt ggtcttcacg ccagaagaat tctccgtctt ccaagcgggc
    24721 taccaagact ttttcatttc ctttaatgac atttttcaaa cgctctgcgt ttccgttacg
    24781 aacagaaatg aagtttggca agagttttcc atcttgatca cgaacaacaa agtaacgctg
    24841 gtgttccttc atagaagtca ccaagacttc ttctggaact tcaaggtatt tagcatcaaa
    24901 acttcccatg aaggcagttg ggtattcaac caaattcaag acttcattca gcaaatccgc
    24961 atcaatttcg atacgtacac catgttttgc ctcaatttcc ttgatttggt caacaatcat
    25021 ttgctcacgt tcacatggat ctgcgattac aaactgctta cgaaggtctt cttcatagct
    25081 caatgctgac tgaattttgg tttctttccc caagaaacga tggccacggc tcacacgact
    25141 tcccttgata tcaaggaaat ccaagtcaaa ctcttgctca tccaagagaa cagttaaagt
    25201 gtgaacaggg cggatgtatt caaagctatt tccagcccag tgcatgctga cagggaaagt
    25261 caatgacttc aagacatcta caacaccagg aacaatggct tcaactgatt ggccaacttc
    25321 ttccttagtg acatagacat attcttcacc cttaatttca cggaattcga tatcttcaac
    25381 agtcaaacct ttcccacgga caaatccttg agctgctttg gtgaagtttc catcactatc
    25441 caaggcaatt ttctttgctg gtcccttgaa atcttctgtc aaatcagact gtttgtctga
    25501 taaaccagtc acacgaacag ccaaacgacg tggtgttgag aaggtttgaa tggcttcaaa
    25561 agacaggcgg ttttccttga ggaaggctgc cattttttcg cctagttgtt tttcacttgg
    25621 tgtgacaaca taggctggta attcttcaag accgagttct actaataagt tttttgtcat
    25681 gttttttgtc atgttttttc tccgaaaagt atctttttat tttccagttt gccttatgtg
    25741 attggcacgc aagcaaccaa cttcgttgtt tcattgctaa aattggagcc aaaagtctcc
    25801 aattttgcct agtatcctta gtttcactaa ggataccttc atcactgcgg caactggctc
    25861 agggctcact ctgttcgccc attttcgtaa tttgtcactc tctttattct gcgtcttctg
    25921 ctaggagttt agctcttgtt tcttcatcca aaagtgggta gcctaggcgt ttgcgttctg
    25981 cgacaaaggt tttggctacg acacgggcca agttacggat acgagcgata tagcctgcac
    26041 gctctgttac agatacggca ccacgcgcgt caagcagatt aaaggtatgt gaacatttga
    26101 gaacatagtc ataggcaggg tgtaccaagc cttcttctaa tgcacgacca gcttcttttt
    26161 caaacttatc aaaattttca agcaacattt cttggtccga aatttcaaat gaatattttg
    26221 agtgctcata ctcaggctgg ataaagattt ctccgtattt tacaccatca gcccactcga
    26281 tatcatagac agagtctact tcttgaatgt aagaagccaa gcgctccaaa ccataggtaa
    26341 cttccgcagt cacagggcta gttgccaatc caccgacttg ttggaaataa gtgaactgag
    26401 tgatttccat tccgtcaagc caaacttccc aaccaagacc agctgaacca gttgatgggt
    26461 tttcccagtt gtcctcaaca aaacgaatat cgtgctccaa aggattgatt cccaattttt
    26521 ccaaagactc aaggtaaagt tcttggatat ttgatggaga aggcttcatg accacctgga
    26581 attggtggtg ttggtagaga cggttagggt tttccccata acgaccgtca gcaggacgac
    26641 gtgatggctc tacataagct gcattccatg gctcaggtcc gatagcacga aggaaagtgt
    26701 aaggactcat tgttcccgca cctttttcat tgtcataagc ctgcataagc atacaacctt
    26761 ggtcattcca aaatcgttgc aaagtcaaaa taatttcttg aaatgttaat ttcttagaca
    26821 ttgaatactc cttaataaaa aataatttct tgcgacacga gtctacctcg tcgattatac
    26881 gaggcaagac gagttagtac tgcgtctagc tcagcaccct agtgctgagc gtggggcagt
    26941 ccgactgtaa ggaggtctct gccactgatg cagtgaaatg tcaatttctt agacattgtt
    27001 tactccttta gtttttatat ttctttttca attaatttct gctgaacaaa ccaatctaac
    27061 aagggaaaag ttttttctgt atttgcccat aaatgataag aatctaagac cgcttgtaca
    27121 ctacctaaat tttctaccaa cttatctact gtcaaaaagc tgcgccagta ttcataaaaa
    27181 atacttgcat agttcttatc ataagtcgaa gaaccaaaat cattcaatga atgccaacca
    27241 tacttcttct gaaaaagttc tacgagagat tgattacaaa ttttttccgc ttgaaattcc
    27301 tcttctgtca agaaatactt gcgactaata tattcaacca tcccctcttc gaaccagata
    27361 taagagtcat aaccatcaaa atcatctaaa aaatgctccg accaatgagc taactcatgt
    27421 cctacaatct gtaagaggaa attttcagat aaagaatgat agtgactttc tattgcttga
    27481 gtttgctgag aacactcgta gtccatcaat tgatacaaat acaactcttt ccaaacagct
    27541 aaatcaggcg ccataaccat tcgtctatta tttgtatagg ctggaacagc gctttcccta
    27601 ataatctgtg tagcagcatt aaaatctgac caaataacgg cttgcggtaa atcacagact
    27661 gcaagttcat tctttaaaaa agattgataa tctttcaact tttcagtatt tcttactaca
    27721 aaatcacgaa atgtagctag ttgactatcg tcttttacaa gataaaggtt gtccacggct
    27781 ctcctttctt tcacacaata gactgaataa gcaaaagaac cacatctgac aatcctaggt
    27841 tgatttaacc taggggcgtc agaaacgcgg ttccacccta atttattact tcattgtttt
    27901 tgaaaatact acagaaagcg ccagcccttt attttgccct acttggctcc cactatccca
    27961 agctcgcttg aagaacgcca taagactttc tttcctgctg actattatat caaaaattag
    28021 aataatgtac aattcttttt atgattttct agaaatccac atcatcaact cgtggagcac
    28081 ccgattgaac agcaatcgtt tttaaggttt ctctctcctc atgactcagt tcaattccaa
    28141 agcaatcaag attagcttga atacgagagg ttgtgataga ttttggaagt ggtaaaaatc
    28201 cttctgccaa gctccaggcc aaggctatct gagcaatcga ttttccgtga tttgctgcga
    28261 tttcttgcac ttgcttgcta tcaaatagtt ctccctgacc aaaaggcccc caagcttcca
    28321 ataaaattcc cttttcacga cagtaagcta cgacttgatc ttgatacaca cctggcgcca
    28381 agcgaacttg attgaccgca ggaacgatag ttgcagtttc aagcaaggca tccaaatgat
    28441 ggggaagaaa attgctaacg ccgatagcac ggattttccc ttcttgatag aggtcttcca
    28501 tcgctctcca aacttccgca ttgcgagttt tccatgcgtc attttctctg agcggttttg
    28561 ggttcggcca atgaatcaaa tacaaatcca aataatccaa gcccagtttt tctatagatt
    28621 tttccaaagc ttgacgagtt tgctcatagg tttgctgact attccaaagc ttggtagtta
    28681 cgaacatttc ttcacgtgga actccgctat ctttgattgc ttgaccaaca ctttcttcat
    28741 tctgataaat cgccgccgta tcaatatgac gataaccagc cttcaaggct tctaacactg
    28801 cacgataggc ttcttctcca tccttagcct taaaagttcc aaatcccaat actggaattt
    28861 ctactccatt atttaattga taggtattca tatgcttctc cttctatttt attcatcaat
    28921 tatagcataa aacatttttt aagtagtact atcttctgta aaaaataagt ctgtcaaata
    28981 tctaacagac ctattttttc ttgcttattc atcacgacta tagtacagct catgagcttt
    29041 taggcgagta ttgagcatct ctggtatggt cacaaaggta taaccttgat ttttcaaata
    29101 ctcaatgacc cttggcaagg cattgactgt cggactgtga atatcatgca tcaaaacgat
    29161 agagccgtta gctacttgat gctgaatttc tgtcaaaata gatgcttcat ttttactctt
    29221 ccagtccaga ctatccacat cccacatgat aaagctcaaa tccaagctat tgcgaatatc
    29281 atctgtaata gcaccataag gtggacgcat gagtttagaa ctagaaccca gcactttagt
    29341 tagcacatcc tcagtatcag taatctgctt tttagcttca tcaagagaga gttgcgagag
    29401 aatcggatgg ctccaactat ggtttccaac aacatgacct tcagatttta tcctcttcac
    29461 caagtcctca ttcccagaaa catttttccc aagcacaaag aaagtcgctt taatatcata
    29521 tttagctagg gtctctaata cctgcggggt cgttgctgga tttggaccat catcaaaggt
    29581 tagagcgaca actttttgat atttcttatc aaagtaagat tggtacaagg ccgcatcttt
    29641 ttcgagtaag tacgaagatt ggataacatc aaagaaagca gatactggca aggctatctc
    29701 ttctaaattt tcaaccacag gacttggata aaggataatc tgactatcct tgtaatcaaa
    29761 attccatgca gacaagtctt ggtcagagaa gttttttaca atctgctcac tctggtcttg
    29821 ctctattttt ttatcctcta tgaaggaggt caactctttt atcagctgtt ccttagcctt
    29881 actagcatct gaaaacagtt ggtcaagtgt aaaaggttgc ccatcttctg ttaagtgaac
    29941 ctttcctaga ctggtctttt cagtctcttc aatcttaaaa gcaactaaat catagatttg
    30001 tttggtcaca ttacgattaa cgactccctt taaacctgac tcttcttgct ctgtatagta
    30061 gaaaacaaga ttgtccttac tttctagctt gtccttaaca tcttgattta tcagctccct
    30121 aacagaggaa atcactttct ccccttggag aggataatag gcaatcactt cggcttgccc
    30181 ctgacgaaaa tgctccttct gatttccctc actcaattga tcatctttct cttttttgag
    30241 cgattcaatc ttttgctcaa aacttttttg ctggtagatc ttaaaagcaa taaatccgcc
    30301 taataggcaa atagaaattg ctaagatacc aatcaaagcc aataatacat gtctcgtttt
    30361 cccgtgtctg ccacgtccta gtctactttt attcatattt atatcataac aaatttgagc
    30421 aataatttca atgatacaat ttggcaatcc acaattcctc tagcaagcca aagcatctta
    30481 catcaactcc aacatccgta tctgtagaga ttatgtagtt ttctatctat ggaatttcta
    30541 gtagattgaa gctagaatag tagacctata cttctaaaac attgttagaa atcgatttga
    30601 ctgtcctgat cgatttgtcc tgttctcatt tcattttact ataaaactat gaaaagctag
    30661 gtcatctgag aagtaattac tatcgacaat tgcgatagcg tatactggtg cgatgtgttt
    30721 gtagctctgg tgggtatcac cttcacgttg gcaaattttt tctaggtttt gattaacctg
    30781 actgcacaga taagcccata ggcgattgat gaaaaaattc tgatgatgaa cctgaatttc
    30841 gatgataact tggattccat tatctaactc cgccaagacg tctatactag tatagaaatc
    30901 ctgcgctgag tagggcatgg aaggcaagac gtgaatgtta cttccctcca aaatcgtcac
    30961 attttttgct ggcaagtcca gcatatcgcg gataaattga caaatcatta gttgggctga
    31021 tacccggatg tctgagaatc ctccttttcc tccttctatt atagcacatt tttaaatcta
    31081 ggtttgctag attctatgct tctatctatt tattcggaaa agaaagcttt tcttcagaag
    31141 aaagctaata gcttatttga aattttctcc tctctgttgg atagtcccgt ctatctatgt
    31201 tataatgaaa gaaggattta aaatcggaaa aggagtattt atgctaaaat taggtgtcat
    31261 cggaactggc gctatcagcc atcatttcat agaagcatcc cataccagtg gagaatacca
    31321 actggtcgca atctattcta gaaaactaga aactgcagca acctttgctt ctcgctatca
    31381 aaatatccaa ctattcgatc aattagaagt cttcttcaaa tcttcttttg atttagtcta
    31441 tatcgccagt ccaaactcct tacattttgc tcaggcaaaa gctgccttgt ctgctggtaa
    31501 acatgttatt cttgaaaagc cagctgtcac tcaaccacaa gaatggtttg atttgattca
    31561 aacagctgaa aaaaataact gttttatctt tgaagcagct cgtaattatc acgagaaagc
    31621 ctttactact atcaaaaact ttttagcaga taagcaagtg ttaggagcag atttcaacta
    31681 tgccaaatac tcttccaaga tgcctgactt gttggctgga caaacaccaa atgtcttttc
    31741 agaccgtttt gctggtggag ccctcatgga tttggggatt tatcccctct atgctgctgt
    31801 tcgtcttttt ggaaaagcca atgacgcgac ttaccatgct caacagcttg acaatagcat
    31861 tgacctaaat ggagatggta tcctcttcta cccagactat caagttcaca tcaaggctgg
    31921 aaaaaacatc acttccaatc ttccttgcga gatttataca acagatggaa ccttgactct
    31981 caacacgatt gagcatattc gctcagctat ttttaccgac caccaaggaa atcaagtcca
    32041 gcttcctatc caacaggctc ctcatacgat gactgaggaa gtcgctgcat ttgcacacat
    32101 gatccagcaa ccagatctga atctctacca aacttggctg tatgatgcag gctctgttca
    32161 tgagctacta tataccatgc gccagactgc tggcattaga tttgaggcag aaaaatgaaa
    32221 accaaactac cgactgaatg gcaagaactg agtgaccaac tcggtttcca agaattcacc
    32281 cccattcaaa ctcaactatt tgagcccctt cttgctggag aaaacctcct aggagtgagc
    32341 aaaaccggaa ctggtaagac cctagcgtat ctcctaccaa gtcttctcag actacaaaag
    32401 aaaaaagccc aacaactctt gattctagca ccaaatacag aacttgctgg acagattttt
    32461 gatgtatgta aaacgtgggc agaagctatc ggattgactg ctcaactctt cctttcaggt
    32521 tcaagtcaga aacgacaaat tgaacgtctt aaaaaggggc cagaaattct gattggaact
    32581 cctggccgta tctttgaact cattaaactt aaaaaaatca agatgatgaa tgtggaaacc
    32641 atcatcctgg atgaatttga ccaattacta gatgattctc agattcactt tgtagaaaaa
    32701 atcactcact acgcacctcg tgaccaccaa ctgatctaca tgagtgccac gaccaagttt
    32761 gaccaagaaa agattgtgcc gaatacacgc actattgatc tctctgatca aaaattggac
    32821 aatatccagc atttctacat gcaggtagac caacgtcatc gagtggatat gctacgaaaa
    32881 ctggctcatg tagaggattt ccgtggtcta gtcttcttca atagcctgtc agaccttggg
    32941 aatgccgagg aaaaactaca gtatcgtgat atattggctg tttccctcgc tagtgatgtt
    33001 aatgttaaat ttagaaaagt catcttagaa aagtttaaag ataaccaact aaccctgctt
    33061 cttgcaactg accttttggc tcgtggaatt gatatcgata gcctagaatg tgtcgtaaac
    33121 tttgatattc ctagagatag cgaaacctac acacaccgtg ctggccgtac tggccgtatg
    33181 ggcaaggaag gatatgttat tactctcgtc actcatccag aagaaatcaa aaaacttaaa
    33241 aagtttgcaa gtatccgaga aattgtccta aaaaaccaag aactctatat caaataaagc
    33301 cccattgctc tatacacatc cagtgtatgg agctttttta taagcaattc aattttatac
    33361 tcatctgctt tcaaaaagca ttctagtcca tctccgatta acgatggact ttatcacctc
    33421 cttctccagt ccttgtatga catcttggag ttgattcatg acatcttcca aagttcgaaa
    33481 ggctttattc ttaaatccac gtttacgaat ctctttccac acttgttcaa tggggttcat
    33541 ctctggtgtg tacggaggaa taaatgcaaa gccaatatta gtcggaatct ttaaggtact
    33601 tgatttatgc catatagcat tgtctataac gagtaaaaaa taatcatatg gataagcttg
    33661 tgaaagctct tctaaaaaga cgttcatcca ctcagtatta catccaccag ctattaagaa
    33721 aactgatgcg cctgtatggg catcaacagc tccataacaa tagcgaaatt ctcgtatata
    33781 gtgactatgg atatgtggac ctactcctat tggagcccaa caagatccca gtttactgat
    33841 tctaccgaaa ccagcctcat cttggtacat caagcgaacc ttacgaaaac gtctactggt
    33901 tttaaagcgc tttcttgtct tcttgaattg agattttatt tttagatgcg acaatggttt
    33961 gagcgtctgc tttcttagga tgttctggac gtggcgtaat atttcgccaa ccatggcgct
    34021 tcaacagttg atagaaggca tcacgtgtgt aggaacgacc taactccttt ttataagcct
    34081 gaaataaggc atcaattgta acaaattctc ctgcctctgc agccttcaaa tggcgggcaa
    34141 gaaaggcttt ttcttcctca actgtcatat atgatggtta cgaccaccac gtgtttcttg
    34201 aaggagagag tcgagtccga actcctcata tttttttaca tttcgccaaa tcgttgtttg
    34261 attacagtct aaaagctcta taatctcttt ataagatttg cccatcagac gaaatagaac
    34321 gatttgaagg cgtttatgat atttagctgt acgagagtct tttaaaagtg ttttgatggt
    34381 ttggatttct tctttaattg atttcatatt actattgtat aatgcttttt gattttagtc
    34441 tagtattata ctcttcgaaa atctcttcaa accgcgtcag cttcgccttg tcgtatagat
    34501 gttactgact tcgtcagttc tatctacaac ctaaaaacag tgttttgagc agtctgtaac
    34561 taactttcta tagtaaaatg aaataagaac aagacaaatc gatcaggaca gtcaaattga
    34621 tttctaacaa tgttttagaa gtagatgtgt actattctag tttcaatcta ttatagttta
    34681 ctctttgatt ttcattgagt attagttcaa tatctaaaaa aagaaccttg ccaagcaaga
    34741 ttcttttagt gtctgactta aataattgtt cttctgggaa ctaaatcgaa ttaagcttcg
    34801 atttctgtaa ccatacctga accaacagta cgtccaccct cacggataga gaatgtagta
    34861 ccttgttcta cggcgattgg gtgaatcaac tcaacgtcga ttgtcacgtt atcaccaggc
    34921 attaccattt cagtacctgc tggaagttcg attgaacctg taacgtcagt agtacggaag
    34981 tagaattgtg gacggtagtt gttgaagaat ggagtgtgac gtccaccttc ttctttagta
    35041 aggatgtaga cttcaccttt gaatttagtg tgtgggttga ttgaacctgg tttagcgata
    35101 acttgtccac gttcgatttc atcacgttga acaccacgaa gaaggacacc tacgttatct
    35161 ccagcaagac cttcgtcaag ttgtttacgg aacatttcaa caccagtaac aactgctttt
    35221 tgagtttctt ctttgatacc aacgatttcg atttcgtcgt tgactttaac gataccacgg
    35281 tcgatacgtc ctgaagcaac tgtaccacgt ccagtgattg agaatacgtc ctcgactgga
    35341 agaagcaatg gtttgtcagt gtcacgttct ggttctggga tatactcatc aactgtgttc
    35401 atcaattcca taacgatgtc ttcgtattta gagtcacctt caagagcttt aagtgctgaa
    35461 ccttggataa ctggaagatc gtcacctggg aagtcgtatt ctgacaatag gtcacggatt
    35521 tccatttcaa ccaattcaag caattcttcg tcgtcaacca agtcaacttt gttcatgaag
    35581 acgataaggt gtttaacacc aacctgacgt gaaagaagga tgtgctcacg agtttgtggc
    35641 attggtccgt cagttgaagc tactacaagg atagctccgt ccatttgagc agcaccagtg
    35701 atcatgtttt taacgtagtc cgcgtgtcct ggagcgtcga tgtgagcgta gtgacgtttt
    35761 tcagtttcgt actcaacgtg cgcagtgttg atagtgatac cgcgttcgcg ttcttctgga
    35821 gcagcatcga tagacgcata gtctttaggt tggttaactg atgaaggcaa gcgacgtgcc
    35881 aaaacagttg tgatagctgc agttagggta gttttaccgt ggtcaacgtg tccgatagta
    35941 ccaatgttaa cgtgtggttt actacgatcg tatttttctt ttgccatttg agtaaaagcc
    36001 tccaataaaa tatattttat agatagacag taggcaatac agtctaactt tccttactat
    36061 tttatcaaat ttcagctaaa ttgcaagtgt tttacaacgt ttttgtgaat tattcttggt
    36121 aaaaatttaa ctaattaata gaaagtacta aatagactta tccttcaagg agttttcagc
    36181 attatccatc cactcacttg ctgaaaatgt aaacagtctc tggtttatat agtaaaatga
    36241 aacaagaata gggcaaatcg atcaggacag tcaaatcgat ttctaacaat gttttagaag
    36301 tagatgtgta ctattctagt ttcaatctac tatacaacct caaaactgtg ttttgaacaa
    36361 cctgcggcta gcttcttagt ttgccctttg attttcattg agtataaaat tgcagataaa
    36421 acgataacaa tcataggact cagcagagtc aatgtaggtc gaagaatagc ccccctaatc
    36481 gcttatttta tagcaaaatg aaatagaaac tgaacatttt gttgaggaag gtaaatcaat
    36541 tcctcacaat gtttgagaaa gaagggggga ctattccaac ttcaatccac tataaagcag
    36601 acttacaaga tagggaaccc atctccgata atatatagta gaatgaaaac tgcacaattt
    36661 gattggagaa ttcaaaccaa tttctaacaa tgttttagaa acaagggtct attatttcaa
    36721 ctgcaaccta ctatagccca ttgaagctgg aatagcccac tgaaacttct aaaccactgc
    36781 tggagaggag tttgtttaga gtttctttca tttccctaaa aaatcaaaaa gagagaacca
    36841 gtctgatcct ctcttactta tagatggtgc tcactcaaat gttaaaggag ctatttctta
    36901 gagataaagg aatttgaata cagctactgc cgcaattgct gctgcgatag gtgctactac
    36961 tggtacccaa gaataccacc attttgaatc gcctttatgc tcaccaagaa ctgattttgg
    37021 aaggaaagca tgaaggagac gtggtcccaa gtcacgggct gggttcaagg caggtcctgt
    37081 aggtcctcca agtgatgtta ccaaagccat aacgaggaat ccaagtgcca agtgagccac
    37141 agaaagtcct gaagcagtgt gtggagccac ctgtgcttta atagccaagt cagaaaaatc
    37201 aactgtttgt cctgcttcta ttgccttttg tttcatgaat tgaagcactt cagcaccaaa
    37261 gaagttttta gtcaaaccaa gagctgcaaa gaacaaaaca aatgaaccaa caaactcatt
    37321 aatcaaacca ttgacagttg ctgcatagcg actttctttt gtaccatggt caatacttga
    37381 aatagttgag aaagttccca agatgttatt tggtttttca gttttcaagt agaatggacg
    37441 gtatgttgcc acaactaagg cttggccaaa gatagccccc aagacttgcg cgataatgta
    37501 aggtaccact tgtgcccaag ggaaaagacc gctaactgca agccctagag tgaaagcagg
    37561 gttgatgtga ttcccagata cgttaccaaa catcaaggct gggatcataa cccccatacc
    37621 ataaccaaca gcgatgacga tccagccact ttggtgacct ttcgtacctt taagttcaac
    37681 gttggcaact gcaccattcc caagaatgat caaaatggca gttcccaaaa attcagtggc
    37741 atacttcagt gcccatgtga aatccatttg ctagattctc cttaaaattt tttagatatt
    37801 ccttatttta tcaattttta ccctatttag caactgattt ctggaaatat ttttaaaaaa
    37861 ataggattca tagtttccca gttcaacgta cttgtaagcg tttttattct tcacgaaaga
    37921 cctcgttctc aaaaccagga aaaaagccca catctgtgag cttttcctgg ttcctagatt
    37981 ctaaaatcta ttatttttca tcttcttttt tcttgaagaa tcctaatact agactagcta
    38041 acaaggtcat gataccagca ctagccaagg tagcattagc ttctgtacct gtgtttggca
    38101 attcctctct cttacctgtc tcataagtcg gaacttctgg gtctggattc actggagttt
    38161 cagtttttgg agtacctggt tctggagttg gctctggtat tggagtctct tgatttggta
    38221 gttctgggtt tggtgtcgga acacttggat gctctggatt tggttgtggg attggttttt
    38281 ctggagtcgg ttcacctgga gtacctggtt cctgaggact tggaatttct ggtttttctg
    38341 gagttggttt atctggtgtt gataaacggt cataccttac cgttatttct ttatcactag
    38401 agtctgacgt aacttcttgt gattcaactg ttggaatatc tggatctttg tacttgtcaa
    38461 tcttaccaga tataacctcg tcccagtttc ctgttgtcca ttcaccgtag gttacaactc
    38521 ccgtgacctt gttctcagtt tttgtacggc ttaaggttac aggttgaaca acatcttctt
    38581 ttacattttg gttcgtaact ttatcaacgt aatgaatgat acgcgttata gtcttcgtct
    38641 cagtagaggt tgctgttttg ggaaccactg tttcctcaac attctcacgg tagtaatagt
    38701 caactgttgc accgtcttct ggtacgcatt tgcaggagtt gctaccaagg tgtatgttgt
    38761 tttccttgtg ataactcggt cttctttgtc ctcagttgtt gttttccctt caatagtttt
    38821 tgattctgtg gtatactcag aacctatcgc taaatcagct tttataacag actctgccaa
    38881 cttctcttgg ctaccttctt tatagtaatt ggctgttact gtagcagtgg ttggcgcttc
    38941 gctttctcta taaactaagg tcactgttct accttcgctt acaatattcc cagttaaact
    39001 tgcagaattt gtatctgctt ctttaaaagt ataatatttt ccgtcagtag tagtcatgct
    39061 actgagtttt ttatctgtga cattatagct ggtaccaatc agttgttttt tattggtaat
    39121 gtaagttccg tcactttctt tttctccaat tccagtatca tttttcaatg atagcaaacg
    39181 cccttgttca tcaacatagc aaactttcac attttctgag attagttctg ccaattctga
    39241 ggtttttttc tttttctctt cttcgggaat atttagtttt ggaatgattt tttcaacaac
    39301 ggttcgtgat ggttccacaa tatcttggat gactgaaaag tcagctagaa ttgggagatt
    39361 atactgaaca cggtgacttt gagtgtttac tcctactctt tcattattct ctgaaaatac
    39421 ttgtacggta taagaaacaa catcttttcc taatagaaca tccccagtag agaaatagcc
    39481 gccttttcct agtttgctat ctccagagtc cacttctttc ctaatcttat cagatagttt
    39541 tttaccagtc agtacattcg ttcgcacaat ccctttgtct acccctacaa agtgggagaa
    39601 ctttttgaac tcttcagaac cagatctagc ccaaccatta ttaagggcat ttgcttttgt
    39661 atttgtattc tctctcaaag gtttggcgat tagaattata ttcatcggca cttagagttg
    39721 ctgctatatc tgactcttga ataccaactt ccttactacc atttctagcg gcagtatatg
    39781 tgtatttatc tgtttctact tctagctgat tatccttaac atgataggta attttctcct
    39841 ggtataagag tcttcagtag tttatatgct ctgtcatcat ctttagcttt agaagcagct
    39901 gagtttagcc aaattggggt attaggagta tctttatcag cctgtttcaa gacattattc
    39961 aagtcatttg ctaacctatt ggttgtcctc actgtgaaag ttttcttcca gtctgaacca
    40021 cttttattag acttagatat gctcatgaaa tcctggtcaa cattcaacac aatatcgcct
    40081 tgttttttag catcttccgt tgcttctgct tcaaattgat catggagttt ttgttgctct
    40141 ggtgtatagt ttttttattt acacgattta atgtactatt ttttatttta gtattaagaa
    40201 ctccattaat acgattttta aattctgctt caaaaaatcc cttaatttgt tggtgcgcaa
    40261 gttcaacatt caaacctttc ttatacaagt cttcattctg aacgatttcg gctacacggt
    40321 gaatggtttg atcgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta
    40381 ctcgataggt tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat
    40441 tcaaaaatag ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa
    40501 gcttgctcaa taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta
    40561 tcttggatgc agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca
    40621 ataacatgag gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa
    40681 tcgcttgtca tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct
    40741 gcaacaattg aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct
    40801 ctaggagccc ctgcataagg acgatagagg tagcggtcga ttcctgtttc gtcaatatat
    40861 acgattggta aattttttag gttatccaaa atatcaagaa actcagcgac tttctctggc
    40921 tcttgttcct taaagctcgt catctttttt taaagtgacc ttaatctgct ttaaagctgc
    40981 ccatactgaa ggaacagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg
    41041 atgagcctct acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg
    41101 ctttttcctc tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg
    41161 acgccaacac caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatgtaatct
    41221 aatgctcgct gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta
    41281 aaactaagca actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg
    41341 aatttttcct aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag
    41401 atgttcgaag cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta
    41461 aatgttttaa aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt
    41521 tgattttgtg gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac
    41581 taaggaagat gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt
    41641 tggtgctggt acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc
    41701 tcgtttgatt gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga
    41761 tagccgtcac ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg
    41821 catcaaatct tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg
    41881 tcatctcaac tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa
    41941 cggttacaag gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt
    42001 gactacttat atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac
    42061 tgaaaaagct tctggcttga ttgaagttat cggcgaagct gttgacatag aataccttaa
    42121 agaggttaag gacataaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa
    42181 gattgtctac acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca
    42241 agcaggattt gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc
    42301 aactgtaaca tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg
    42361 tcgtcaagtt ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt
    42421 tgaagttctt caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat
    42481 catggctaaa tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc
    42541 tctctgcaaa tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc
    42601 aactatgttc aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga
    42661 agaaaaacac aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa
    42721 accatttgta cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc
    42781 ctactaccgt tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata
    42841 tggctactac gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca
    42901 aatcaaagcg attatggcta aattccgcaa caatgctcca aaagaatgga acgaaacagc
    42961 tatcactgtc gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac
    43021 aaacttgaca actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat
    43081 tgccgttcgc ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga
    43141 aaccaacgaa gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt
    43201 aaaataaaga cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta
    43261 agcaatttta gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg
    43321 gaacaatttt tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa
    43381 gctcttgata aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc
    43441 cgtaaatttg cagatacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc
    43501 atcaatagtg aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga
    43561 atcccaactg taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac
    43621 tcttcaatgt cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa
    43681 gtcttaaaat cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta
    43741 ttgttcctaa aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa
    43801 atcaattttt aacaatgttt tagaaatcac agtgggctat tccatattca attatccata
    43861 ttcaatcgct attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg
    43921 cagtttcagc cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt
    43981 ctccaaacca tttttggctg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag
    44041 cttcatttat cttcttaacc aaggttgtat cttccttacg ggctccaacc gcaaaagctt
    44101 ctgtttctag tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat
    44161 aatagtttgc atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa
    44221 tcaaggcttc attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca
    44281 aaatttctgg atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg
    44341 tctttccagt catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct
    44401 gctcattctt catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg
    44461 aatagccatt ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc
    44521 aatcaatcgg ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat
    44581 caatatcaaa tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac
    44641 tatcaaatcc aatagtaata gacttgttag actggtactt tgaccaatta tctccactag
    44701 tttcgctaga atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata
    44761 caagcatcca ttttttcatc catttttcct cctatttagg ttctactttc aataatacat
    44821 ctgcgatatt ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt
    44881 ccctattttg caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag
    44941 ttggttcatc gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc
    45001 gctgcttttg cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta
    45061 actgttccaa gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct
    45121 tcacaggcga taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt
    45181 ggaagacaaa tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat
    45241 tataaaagat ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg
    45301 tcttacctcc accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac
    45361 tgaaatcaga caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca
    45421 tagctgcccc ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca
    45481 caatcccaat taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat
    45541 cgcggttagc agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca
    45601 aagaagtatc cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg
    45661 tcacttgggg caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg
    45721 cagcctcata ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt
    45781 aagctgcata gttgagaaca aaggcaataa tagctgcagg aaggcggtct aaacgaatcc
    45841 caatacttgg gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca
    45901 taacccagat gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa
    45961 aggcaatcaa aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag
    46021 tcgtgctcgc accattcagt aaactcggta atatctcaaa taaataagac atactgcacc
    46081 tcctaaaagt aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta
    46141 aaaagattct accatataca aataaaaacc gtagctatca aaagagataa actacagttc
    46201 tatatgttta aacattctta caatctctca aacagttctt gcatttgcac atcatctgga
    46261 accagtttta agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc
    46321 aagagataga tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct
    46381 tgataatgct cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc
    46441 cacttggtca aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc
    46501 tcctgctcca gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct
    46561 tcttttgcag taaggagata attttctgca ccactagcat catgcaattc ataagaaaat
    46621 tgtgaagcag ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg
    46681 atacgcaggg cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca
    46741 tagccttcaa agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga
    46801 tattcttctt gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct
    46861 aactccaggg ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag
    46921 gcaaagccaa ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct
    46981 aactgggcat aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc
    47041 aaacccaata tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt
    47101 gccacatctg tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca
    47161 taccagtcac tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca
    47221 tcctcgctag caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc
    47281 aggtaaattt ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca
    47341 tacagaagat cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt
    47401 aaatcttgct cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc
    47461 accctctaat tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac
    47521 aaccttagca gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga
    47581 tcctgaagtt aacaaaacaa agagaacatt aatagggtgg atgtttaatt gacttcccaa
    47641 aatcaatgga gagacaaaac ggccttcaat agtttgttct acgataaaga caatcactac
    47701 tttcaaaagc atgactggac cagcaatcaa acccaatact agagcaggaa gcatggctag
    47761 aaagctacca agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc
    47821 atagcgtaga ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac
    47881 tgtcacttgc cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc
    47941 aacaggttcc ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc
    48001 atcacgcaag agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga
    48061 agccccgcta ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa
    48121 aactgtagcc tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc
    48181 tggcagatgc tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg
    48241 aacgtttctt gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc
    48301 ccaaatgata aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac
    48361 cttatgcttc tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa
    48421 aatgactggc aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat
    48481 cttacttaaa ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc
    48541 cttgttatct aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc
    48601 cataaatact tcctttctat tgttctctca ttataccatt tttgaaacaa aataactctt
    48661 ttttaaagtg cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag
    48721 tcttatcttt acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac
    48781 gtcgtacttc tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa
    48841 atctagaact ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac
    48901 atttatacac tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg
    48961 ggactgtgtt aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg
    49021 aaaagcgtga tttggtttac gcagctaact atcacaaggg acaagtcctt gtttataaac
    49081 gccaggaaga tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac
    49141 atgaaaatca agcttccccc catgttcact atacagattt aacacctgac cactatctag
    49201 tgacctgcga cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat
    49261 tatctaagct ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc
    49321 ataaccacta taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa
    49381 tctacgatgg cgttggcgaa tttgaacgta tgcaggtcat ttcaacttta ccggaagctt
    49441 acgaaggctt taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg
    49501 cttctaaccg tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag
    49561 agttattaga aatcgttcca acgcatggtc agactccacg tgattttgat ttgacacccg
    49621 accaaaaatt tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta
    49681 attgtgacaa tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct
    49741 gcatccgttt tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt
    49801 tttcttatag tctatttccg acattaatac ggttaatagc acgttgcaaa gcaatcttag
    49861 cacgacgttc ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac
    49921 gaagtttggc acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag
    49981 cgacgattgt gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt
    50041 tcacgtgatc tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa
    50101 tcatattttc atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat
    50161 agctggcatg gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag
    50221 ccatagatca cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa
    50281 cctacaccac ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta
    50341 aagccacgta cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc
    50401 gcaacgttga agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc
    50461 ttttcttcat cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg
    50521 taacgttgaa ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt
    50581 tcaggtgcca aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat
    50641 tgtaccaact tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc
    50701 gctgggtcag tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc
    50761 ttcttggttg atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg
    50821 taaccaacgg ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg
    50881 aaacggaaga tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat
    50941 tcagcgattg tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc
    51001 tgaccaaaga ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg
    51061 tcattcccct cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct
    51121 tgggcaatgt tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg
    51181 aaaagtccaa ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct
    51241 gtttcaagga tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt
    51301 ggctgacgct ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg
    51361 ttgaagacac gtcccaaagt ttctttacct actggtacag agattggacg acctgtgtcc
    51421 aatacttcca ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata
    51481 ccatctccta actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg
    51541 tagacgacaa gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct
    51601 acaacgggac cgataacctg agcaatttta cctgaactca tctccttctc ctattctata
    51661 taagatactg tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac
    51721 tagagcctat tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc
    51781 cgcctgtctg gcacggttat actgaattgt caaatcattg atgactttct tagcattatc
    51841 tgtcgctgtt tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat
    51901 ggcaccgtaa atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg
    51961 gctggtttcc aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc
    52021 aacaatcgga agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt
    52081 gtagcaaaca taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat
    52141 aatcttacga acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg
    52201 ttgaataccg cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa
    52261 acctttaccg tctgggtggt attcttcttt caactccata acagctttca aaatagagga
    52321 attataacct ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac
    52381 agaacggcta atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc
    52441 tgtcaaaagt ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga
    52501 acgacctagc ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt
    52561 tgttgaggcg atttttgttt taatatcatt tagagatact gccatctgac acctctattc
    52621 ttattggaag ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc
    52681 tggcaagtct tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa
    52741 ggtatggaac tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc
    52801 atgtgtcaaa gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg
    52861 ttgtttcaag acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc
    52921 caagtcagaa ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg
    52981 aagtgtacca gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac
    53041 agatgaaccc gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa
    53101 gatttgtcca tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc
    53161 ttgtgtctcg ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt
    53221 agctgagcgc tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg
    53281 acctggagga cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag
    53341 atcatcgtat acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac
    53401 cccagtataa ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac
    53461 gattgtgtag tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga
    53521 ttctttttgt ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat
    53581 tgtatcaatc gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg
    53641 accacgacca atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga
    53701 aacagactta cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt
    53761 gtggatttct ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag
    53821 actttcacct acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg
    53881 gatatctgta aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc
    53941 cataccataa gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc
    54001 atgagcacgc gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa
    54061 attgggtttg aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat
    54121 tgccaaaaga acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta
    54181 atactcacat caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca
    54241 tcgatttgtt cttttacact ccttactttc agagacattt ttttctcaat caaagggagc
    54301 aaacgagtct tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga
    54361 tttgtttctt tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct
    54421 ctgtgattgt aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg
    54481 aaaaaagcaa ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa
    54541 ggcagacctg ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct
    54601 tcttctcctt tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt
    54661 actgttttct tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt
    54721 tatgggcatg actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat
    54781 ctgcgacctc acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat
    54841 tggctttttc ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac
    54901 tttgctcagc tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag
    54961 ccaattcatc ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc
    55021 tgtcaatatc tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc
    55081 atgcaaattt tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat
    55141 taccaattaa ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata
    55201 ttaatcttat tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag
    55261 gaaataaaga cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa
    55321 taaatagctt ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata
    55381 ttcccaaaaa tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc
    55441 ggtatgacaa aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga
    55501 acgctttcta tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atacggtaaa
    55561 ttagcggttg gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag
    55621 ccaaggttat tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct
    55681 ttcatgtagc gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac
    55741 tcaagtacat tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata
    55801 aagacaaaaa taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata
    55861 acaggaccaa tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct
    55921 tctcgttcca tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc
    55981 ttcaataaag gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg
    56041 gcgtgctact gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat
    56101 acaggcaata cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa
    56161 tttacttact tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag
    56221 cgtttaataa aaattatttc cattttgcta aatttcaagt tcaagttagc catccagaag
    56281 tcttctctgg gtgacttgta gtccaagcat tttttaggat agttgttaat ccacttttcg
    56341 atgaatgcga cttctttggg agtcattttc ttggttccct taggtaacca tctacgaatg
    56401 aacctgttgt gattctcatt agttcccctt tcccaaaagg cataggggtg cgcataataa
    56461 atgtgctcct cagaaaatac atcaaacaag cgattgaatt ccgttccatt atctgccgtg
    56521 atggaaagaa tcttgtgttg ttttaagatg agttttagag cctgattgac cacctcagca
    56581 cttttatttg gaatcaatcg gatgatctga tgtctactct ttcgatccgt caagacaagc
    56641 aagcagtagt ttttcgctct cgtaagtaga accgtatcaa tctcataatg cccattctcc
    56701 aagcgaagat tgatagcttc agaccgctgt tcgatggatt gaccagcagg tttaaagttg
    56761 gtgctagcct gtttcttaag cgcttttcct tttctagggt aaagcagatc ctgtttgctt
    56821 aaccccaatt ttccatgatg aatccaatag taaatggttg aaattcccac gttaacccct
    56881 ttagccatca ccatcatttc aggcgaaaat ttttggttat gatagtggag aatcttttcc
    56941 tttagttcct tggtcacgct tgatttcttg accgagcgct tgcgattgtt ttcataagac
    57001 tgttgagcat agtcggcaga ataaacctct ttgaagcgcc cttttccaag acattgtcgg
    57061 actgtcccac gcttgatttc agtgtggata gtttgaggag cttttccaag tagagaggca
    57121 atttctctat ttgatttccc ttcttttttc catctttcga ttaagcgacg gctatcgatt
    57181 gtcaaatgtt tggcttttgt agtataattg tcttgcattt ctgtgccttt cttgtgtttg
    57241 tggttgaaca acaagtataa cacagaggtg ttttcttatg cctacaagag ttttcattat
    57301 ttccattttc tttcggattt cactctattc tgaaaaactt gtgtatattt actgaagcta
    57361 gcaagtctta cctgtaaatt taatgaaagc aacacaaaat cctagagggg aatctcggat
    57421 taatgtcaat ttaaaaagat agagagtttt tagtttaaat aaattgtttt aaaatatcaa
    57481 caacatcact tcttttctta acctgataag ccttgattcc taattttgga gctacgatta
    57541 tattgtcctc aatatcgtct agaaagacac aatttctagg ttataactgg tatttatcga
    57601 tagttactca tatacatcag tacacctcca tacttatgtg cgagcctctc tttgtattat
    57661 acctccatac tcaccttaca gattcttttg gtaataatat ctttgcctaa tgtagagata
    57721 gtcttgcaaa gaaaaaactt ccttgtagcc atgtttctga taaaagtccg gtgcctggaa
    57781 ctgataagta ttgacaaagg caaaacaaca atttcgattc ttagcttcac tttctgcctg
    57841 ttgcaatagt tttgaaccga ttccttgccc tcgcagttcc tcttttacaa acaaatactc
    57901 gatttctagc caatttccaa aagtctctgc tatcaaaccc gcaaggagat tgcccttttc
    57961 atcttcgaca taaagattaa gtggctcact ttcagcctct tccctttttg aacggttata
    58021 aacacgaatc agattcccta tttcttgcga tttatgtgat tccttatttt ccaatctaaa
    58081 gtataatgaa atgaaataaa acatgcgcaa atcgattaag gaatttaatc taatttctaa
    58141 taatgtctta gaaatcaaag tttactattt taacttcaat gcactataca tctaatactc
    58201 aatgaaaatc aaagagcaaa ctaggaaact agccgcaggt tgctcaaaac actgttttga
    58261 ggttgtagat agaactgacg aagtcagctc aaaacatggt tttgaggttg tagatgaaac
    58321 tgacaaagtc agtaaccata catacggcaa ggcgacgctg acgtggtttg aagagatttt
    58381 cgaagaatag caaaatggaa aaaggagtga gtgaagcaca tcgcctcccc actccttttt
    58441 ctgtttttag gctgtttttt caaccttcaa gatttttaca tcatagctac caacaggcgt
    58501 ttcaatggtt gctgtgtcac ctgttttctt gccaatcaag gcctgcccaa ttgggctttc
    58561 atttgaaacc ttacctgcaa aggcatccgc accagctgaa cctacgataa tataaacttc
    58621 ttcttcgtcc tcaccaattt cttggatggt gactgtttta ccaatcgcta cttcgtcctg
    58681 ggcaactgcg tcgctattga cgatttcagc atagcggatt tttgtttcta agctagagat
    58741 ttgtccttcg acaaaggctt gttcatcctt agctgcttcg tactcactgt tttctgaaag
    58801 gtcaccgtat gaacgggcaa tcttaatgcg ttctaccact tctggtcgac gaaccaattt
    58861 caattcttct aattcttttt caagtttttc cttttcctca agggtcatag gatatgtttt
    58921 ttctgccatt tttctcaact ttcttctgat aatattttct aaagaaaatt atgtgacgta
    58981 tcacataatt ttagtttgtt tagtttaatt tgctgttgac atgttcagcg acattgcggt
    59041 cgtggtcttc ttgattgtta gcatagtaga ccttgccttc tgtgacatct gctacaaagt
    59101 agaggttatc gctcttagtt tgattgatgc ttgactcaat cgcatccaga cttggactat
    59161 cgactggacc aggcatgaga cctacatttt tataaacatt ataaggtgaa tcaatgttgg
    59221 tatcaatcgc aacatcctca gctagactga tattttgccc cagttttcct tgggcataca
    59281 agattgcaat attactttga agtggcatat cacgatttaa acgattgtag aatacacctg
    59341 caatgagctt acgatcttct gtcttggcac cttctttttc gaccaaggaa gcaatggtca
    59401 acaactcatt gacagtcaaa tttttagatt tgatagtact atagtaagga gataggttct
    59461 tatccatagc agctaacatc tcatcaatca agctctcaat agttgtgctt tccttgatag
    59521 agtatgtagc tgggaaaagg tatccttcca aacgataacg cgcaccgctg tcttttacag
    59581 gcaaactttc cagtaaagta ggatatttcg ctactgcttg actgataaac gtctcatctt
    59641 gaactttagc caagaaagcc tccgctgtca aagactcttt gaagtcacct tgcaattgac
    59701 ccacagcttg agcaatctga tccaaggtat aaccttctgg aattgtcaaa gtcgcaagta
    59761 caggttcttg cggttcatct gttccacctt tttgcaactc tttgagtaag tcttctgtac
    59821 tcatactctt ttgcaaattg tagtaacctg ctttcaagtc ggtataattt ttatacttgg
    59881 cataaaaact aaaaatcaga ccatgcttta ccaaaccagc tttttcaagc gtcgtaccga
    59941 tttcttgaac gtttgaacct tctggaattc caaccgtcac atatttctta gaattagcat
    60001 cgataggtaa caaagaatct agcacgtact ggtaaccgaa gtaaccacct gctgagagca
    60061 aggcaaggaa tacaaggaat gaaatcacaa aagctttcac atgtgacttc ttctctttct
    60121 taggcttaac gggttttgct ccttctctac ggctacgacg tgatgtatca ctgatgatat
    60181 ccactatttc tgtagcaggc gtaggtgttt ctggacctgc ttgttctgct tttttctctg
    60241 ccgtcgtata ggaaacagct acccttgttg gggtttcatt gtattctctt tcaagtttct
    60301 taggtctaac aggacctgga cctggtcttg atccactttc ttccgctgga gaagaaggta
    60361 catcttgact tggatgactt ggaacaccag gagtttctct ttgactctca tctgctggag
    60421 aagctggtac accttgactt gggtgagtag gcacggtagg agcttttctc ataatctcct
    60481 ctaccgttga caaggaatca gccatgagtt cttcagctga aggttcattt gcaggagtgc
    60541 gaactactgc ctcatcttct ttcagaactt catcatagcc ttttactttt tctaaatctc
    60601 tcagaatctg ctctttaaag cttaatttct cttcttctct tgacttttca ctcaaaagtt
    60661 tttcctcctt gttgataatc cataatatta tatcttaaaa gtccaaaaaa agcaatctat
    60721 gatacttttc ctaacttatt ttttcatttc ccagaccata tcataccatg tttcccctgc
    60781 aaaggttgac tgggactggc cttcgttgac aaatccatgt ttttcataat aggcgatgag
    60841 atagtcatga caggttagat taatgccatc tctctcatct tcaagagcaa cttctttcaa
    60901 ggctgtcagc aatttctgac ccagtccgag tccctgtgcc tccttggcaa tagacagaca
    60961 ggtcacagag atataaccac caggctcatg actatagtct tttatttctt ctgtaaaaga
    61021 ctggtcttgc agatggcggt gcaggccaac tggtccttcg atataaccca tgattcttcc
    61081 ttctttttca gcaaccagaa aagaggtctg aatttctctc aaatgtgctt caaagacaga
    61141 aggaggaatg gcttcttcga ccgaaaaatt ttcaaattca agttcaacaa tccgatccaa
    61201 atcttctaat cttgcttgtc tgattttcat tgttcctcca gataaaaggg attaaaccaa
    61261 atcatactat agccctggct agttgcatag agcaaagttt cttcttcatc aacaaaaccg
    61321 ttcatttcaa aataggaaag cagctcatca ggactctcca aacgaatccc tttgtaatcc
    61381 agctcaactg ccacctcttt caaggctgca agaagaagtg ttcccaggcc ctgtctctga
    61441 tggtcagact cgatgactaa agaatgtact tttagacatt gcggattgtc tgactgggga
    61501 cttgataaaa tatagcctaa aagttgattt tcatccctag ctagaagaaa ggtatccgca
    61561 cacttacgga tactttcttc taaaatatgg gaaagttgct gcttttcagc tggaaaagac
    61621 gaggtctgaa gtgcccctat ctcaggcaaa tcaaacttgc ttgcctgaat gatcttaatt
    61681 ggaatttcca tgggaacatc ctattgaaca ttgcttgtca agttagacaa gagacgctca
    61741 aatgagtatt cataggtttg gatgtctcct gctcccataa agacgtaaac agcattgtca
    61801 tggtctagga gtggagaaac attttcaaca gtaatcactt ggtgtttttt gttgatttta
    61861 ttggctaggt cttctacctt aacgtcacca tgatctactt cacgagccga gccataaatt
    61921 tgcgctagat aaacagcatc tgcttggttt aaagcatggg caaagtcgtc caacagggca
    61981 atggttcttg taaaggtatg cggttgaaag actgctacaa tttccttgct tgggtatttc
    62041 tgacgagccg catccaaggt cgcaataatt tctgttggat gatgggcaaa gtcatcaata
    62101 atcactgtat cattgacaat tttctcagtg aaacgacgtt taacaccggc aaatgttttc
    62161 aagtgctcac gcaccaagtt caaatcaaat cctgctgtgt aaagaagacc aataacggct
    62221 gtcgcattca tgatattgtg acgaccaaag gttggaatgt ggaattgccc caagttttgt
    62281 ccacggaaat gaacggtgaa ggttgaacca gttgttgaac gaagaagatc actagctaca
    62341 aagtcattgc cttcagcttc aaaaccataa taataaattg gtgcatcaga cgtaatctta
    62401 cgcaattcag catcttcacc atagacaaaa agacccttgg taatttgttt ggcatagtcg
    62461 ttaaaggcat tgaaaacatc ctcgagactt gtgaaataat ctggatggtc aaagtcaatg
    62521 ttggtgataa tagagtattc tgggtggtaa ggcatgaagt gacgctcata ttcgtcagat
    62581 tcaaagacaa aatatttggc attagccgaa ccacgacctg tcccatctcc aatcaagaag
    62641 ctggtatctg taatgtgaga caagacatga gacaacatac ctgtcgttga agtttttcca
    62701 tgtgctcctg ctactcccat gctaacaaag tcacgcataa agctacctag aaactcatgg
    62761 taacgtttgt agctgatacc attttggtcc gcataggcaa tttcgacgtt gttatctgga
    62821 cgaaaggcat ttccagcgat aatttccata tcaccgtcta gattcttttc atcaaaagga
    62881 agaatggtaa ttcctgcctg ctcaagaccg cgttgggtaa agtagtactt ttcaacatct
    62941 gatccctgaa ccttgtgccc catctggtgc aacatcaagg ccaaggcact catccctgat
    63001 cccttaattc cgataaaatg atatgtcttt gacatgtttt ctcccctatt ctgtcattct
    63061 ggtcagattc aactcttggg caacccgacg ttcttgttct gtttgtttac tttttttatt
    63121 gtagatttgg ctcttcttta gaaaatcata attgtttttc tttggagcag gtgctgacac
    63181 ttcttcattc ttggtaggga tagaatgaac ttcttccgcc aagatataat gagactgggt
    63241 caatttttgg ctatatttga caaattcacc aggattttcc ttttggaaag gagttgtcgg
    63301 ttgattgccc tgtctaacta gactgggctg agaatgacgt ctcgcaaggc tgaaatcctg
    63361 agttaggtag ttagcagagc gtttcttttt caagtccgca cgcgcttctt cacgcgccac
    63421 ctccgcatag ctctttcctt cttttttaac ccctaaagga gcctttttag gtttttcgac
    63481 ttgcttttca atcggtttta ctggtttttc ttcagtaata ggagcccatt ctaaataatt
    63541 tttatctcga tactcaccct tgatattact gatcagatca gactcatcat agagattcat
    63601 gactggcatt tcagtcaaca tgacctcgtc atctgacacc aatggaaatc gttcttgttt
    63661 cattttctat ttcctttcaa cacttcatta tagcgtattg tcttgatttt tcaagtgctg
    63721 gcttcagaaa ttcccaaaat ttctctaatt tctgctaggg tcagactacc acgtgactct
    63781 gtgccatcca atacttgtga caccagatgt ttcttttgtt cttggagttc ctgaattttt
    63841 tcttcaatgg ttcccttggt caccaagcga tagacctcaa ccgtttcttc ctgacccatc
    63901 cgatgggcac ggccaatggc ttgcgcttcc accgcaggat tccaccaaag gtcaaccaag
    63961 atcactgtat ctgcacctgt caggttcaga ccgaccccac cagccttgag ggaaatcaga
    64021 aaggcatctc tttctccttg gttaaaggcc ttggtcatgt cttgtctttc cttggctggg
    64081 gttgaacccg taattttaaa ggatgtcagg cccaagtctg gcagttcttg ttcaattttt
    64141 tccaacattc ccttgaactg agagaaaatc aagacacggt gtccgccgtc tgccacctgt
    64201 accagtaggt ctcggagact atctagtttg ccgctggctc cctgataatc ttccataaac
    64261 agggcaggag tgtcacatat ttgacgcaag cgcatcaaac cagataaaat ttccacacga
    64321 cttcgctgaa attcctgttc tgacacttga gccagatggt ctcgcatctg ttgtaactgg
    64381 gcaaggtaaa tagccttttg ctggtcttcc agttcatttt tataaaccac ctcaatcaag
    64441 tctggcaatt cagtcagaac ttcttctttc ttgcgtcgca tcacgaaagg cttgataaac
    64501 tgagccactc gctctgctgg caatttcata aattctttct tgcttggcaa aagtccgggc
    64561 atgacgattt ggaaaataga ccacaactca cccagatggt tttcaatcgg agttcctgac
    64621 aaggcaaaga ccgacggcac cacaaattgt ctcaaggtct gggcaatctt ggtctgggca
    64681 tttttcatga cctgagcctc atctaagaaa aggaagtcaa aggccatccc ctgataaaac
    64741 tcactgtcct gacggaaggt ggcatagcta gtcacataga tttgatggct ctcggcaaga
    64801 atctcctcac gacttgcttt caaaccatga acaacagcca catccaactg tggggcaaat
    64861 ttctgaaact catctgccca gttgtaaatc aaacctgacg gagcgagaat caaaacccga
    64921 ctttcttttg tcacttgact agtcaaaaaa gcaatggtct gaagggtttt cccaagtccc
    64981 atatcatcag ccaaaatccc accaaaacca taatgatgga gcatctgcaa ccagccaatt
    65041 cccttttcct gataatctcg caagtcagcc tgaacctgag ttgcctgtcg aggaaagtcc
    65101 tctggatgtg tcaaatcctg ggccagattc tggaattctt gtgaaaaaga aacacggtct
    65161 cgcccttcaa agagatgagc taaactgtag gccaaggatt tccgagcctg caaggtccca
    65221 tcttttaatt caaattgccc cagttcctgt agattttggc gaattttctt ggtttcttca
    65281 tcgaaaaagt aaacttgatt agacgaatca atataaaaat cctgattggc aaccaaggcc
    65341 tgcatggctt ggtcgatttc ctcctgggca atatcttgaa aatcaaactg gatttccaag
    65401 agacctccct tggaggcaat ctgcacctga ggacttgcta ggctataaag ctcttctagt
    65461 ttatctgata ggtcaacatg cccgagtttt tcaaagactg gaatgatatc atgaaaaaaa
    65521 tgatagacag actccgcttt taaggcctga cgccaagatt gaaaatcggc ttcaaagccc
    65581 gcagccaaac agacttggaa aattctttct tctaagtctg cgtcacttga aaatggtaat
    65641 tcttctagct cttgtcggct agatacctgt ctatttccat aatcaaactg aatttccaaa
    65701 cgaatccgat tatcttcttc cctgtcaaag taaaaagagg gcgcaaaagt tttgatttgt
    65761 agacgttctg gagctgaaac ggtgcccatc tggataaaaa gagtcagaca ggaggccaat
    65821 ttgtctcgat cactgctatc aaattgcagg tatttctttc cttgttgacc cacaggtaac
    65881 gctttaattt ccttgagaag acgcatctgc tggtctgtta aaaaataaac ctgaccttta
    65941 tggaaaagta ctgctccctg ataaaagaca ttgaccctag gactctcact gatttccatt
    66001 tcaaaatagt ccgagtattc tgttactgta aaggcaaata gattggcatc agcatgcata
    66061 tcctgaaaaa gcagggtttg gtagctatcc acttgatggt caaattgaaa atggggcaag
    66121 gccatcagta aattcacacc ctgctcaaaa aaggtcagag ggaaaaagag gtgccgacct
    66181 tggttttgga aaaagaggtc tgaaaccagc ccttcctccg ttagtccgtg caagaaagtc
    66241 aaaagttctt ggctggcatc atcaaaggct tcccaagaaa gagactcctc ataaatcttg
    66301 ccaatcatat acgactttct ctgctcgaca atccttaaaa aaagtggaat atcccgaatg
    66361 acatagtatt tttggctatt gatttggccg attctcagag tccacaagat atgattggtt
    66421 cctgcttcca cctgacccac agctgataac tcataggcgc attctgattt tggagataaa
    66481 attcgatcca aaaacttgcc acccaaggtc accttggttt caacggcctc tttttcttca
    66541 tgaccttctt ccagactcca caagatttcc tgaccacgct catcattttt cagaaaatgc
    66601 tctagcgctg ccaaatgcac acagtaaccc ctcttttgaa aaaaatcaca ggcacaaaaa
    66661 accaaatcat cctctaaact atagcgcagt tcttcttctg caacgcgagc gtagagccga
    66721 ttgttctttt ccttgatgat atcaacctta ccagtttcat aaagggcaac accttcgata
    66781 cgaactttcc ccggaatcaa tttagccata ttttcacctt taccttatct ttttattata
    66841 ccatattttc gcctatgaaa atagccttct aggaagactt ttctcctaga aggctggatt
    66901 tttaacgttt ggcaaaagta gccacaatcc gctgacagac ttcttgcaac agagatttgg
    66961 gcatagctat attgatgcgg gcatggagac ttccttcctc tccaaaatcc aaaccacggt
    67021 tgaggataac cttggcttca tttctcaaca actcttgcaa tgtttcatca gtcaggtcat
    67081 aagctgaaaa gtcaagccaa atcaagtagg taccttgcgg tttcatgacc ttgattttag
    67141 tctcttttcc aaatagatcc atcacataat tgatgtggtc ttcaaagact tgcttgagtt
    67201 cctctagcca atctttaccg tatcgatagg cagcttctgt cgccaaataa cccaagcctg
    67261 aaatttcatg ctgattattg gccaacaggc gtttctggaa agccagtctc aacttaggat
    67321 tttcaatgac tgcataggaa ttttttgttc cagcaatatt aaatgtttta gtggcactgc
    67381 tcaagacgat agcaaaattt ttgaaggcag gattgatggt attgaaagac tggtgtttgt
    67441 gaccaaagag ggtcaaatct tggtgaatct catccgaaac taacaaaaca ccgtgttttt
    67501 ggcagagttg gccaatcttc tccaacactt ctttttccca aacacgtcca ccaggattgt
    67561 gagggttgca aagaacatag agtttaacct cctcttccac caaatccttt tcaagttggt
    67621 caaagtcaat ctcaaacaga ctatcctttt ccactaagga attagtaatc aatctacgat
    67681 tattcaactt gacactgcga gcaaagggtg ggtagacagg cgtgttaatt aaaaccgcct
    67741 cgccttcttt tgtaaaggtt tgaatagctg ttgagatggc tggtaccaca ccctcgataa
    67801 agacaagagc ctctttgtca aagttgtaac cgtattgtgt agcttcccac ttttgaactt
    67861 ccttaattaa gtcttcactg gcataggtat aaccataaac cagttggtct gcgtaagttt
    67921 gcacggcttg gcggatttca ggcaagacca caaagtccat atccgctatc caagctggta
    67981 gaacttcact atccgtttct gtttctttcc atttataggt atggtgccct aaacggttgg
    68041 gcaggcttgt aaaatcatat tttcccatct ttgtcttatc cttctaaggc ttggcgcaaa
    68101 tctgcaatca aatctctagc atcctcaatc ccaatagaca aacgcaagag gtcatctgtc
    68161 aaaccataag aatggcgtac ttctgctgga atatcagcat gagtttgagt cgttggataa
    68221 gtaataagac tttccactcc gcccaaactt tccgcaaaag agaagacctt gagactgttc
    68281 aaaatatgag gaatgcgtgt ttcatcggct actttaaagg aaatcatgcc tccacgacca
    68341 gtgtagagaa cttccttaac tgctggagaa tccttcaaaa aggcaaccac ttcttgggcg
    68401 ttagctgttg agcgctccat acgaagagat aaggtcttga gaccacgaag caactggtag
    68461 ctgtcaaatg gagacaagac tgcccctgtt gtattgagat tgtaaaaaag cttctcgtat
    68521 agttctaaac tattggtcac aaccactcca gccaagacat cattgtggcc tgctagatac
    68581 ttggttgctg aatggagaac gatatctgct ccatcttcaa tcggacgttg gtagataggg
    68641 ctatagaagg tattgtccac caccactttg gcacccttag catgagccaa ttttgctagt
    68701 ttttcgatat caaattccaa catcaaggga ttggttgggg tttcgatata gagaacatcc
    68761 acatcctttt ctaactcggc aatcaactct tcttctgtat tggcataggt aaaatggaaa
    68821 tgaccttcct gctccacttg gttaaaccag cgaaaagaac caccgtaaag atcacgcact
    68881 gccaagacct tacttcctac tggaaagacg ctaaaggcca gtacaatagc tgacatccct
    68941 gagctagtcg ctagggcata gtctgctgac tcaatagccg ccaagacttc ctcagcctta
    69001 ctacgagttg gatttttagt gcgcgtatag tcaaacccag tagatcgacc aaactctgga
    69061 tgctgatagg tcgttgaaaa atgaagtggt gtcaccaaag cacctgttgc ctcatctgac
    69121 ttaatacccg cctgggccaa aattgtgtta atgtgtaatt ccttgctcat acaatacctc
    69181 caaatctata gtaactattg taccacttat tttcatcaac tcattttctt cttttcaaga
    69241 gctagttata gtttcaaact atataaaaag ggagtttttc ctgctccctt taatagacta
    69301 taaaatggtg aatctcaaaa gacaccttca ctctatcatt tgctcctgca caaaacgagc
    69361 ataacgctca tgattttcca gtagttcctt atgagttcct gagccagtga ttttcccctc
    69421 ctctaagaag aaaatacaat ccacatcttt taccgtggac aaactatgcg ctataatcac
    69481 aaccgtcttc tcctttaata cagaatagag gctactgata atcgcatact cagaatccgc
    69541 atcaagatta gcagtggctt catcaaatat aagaatttca gcatctttta agtaggttct
    69601 agctatttga agtctttggc tttgcccccc tgacaagaat cgtccgcgtt caccaacttc
    69661 agtatctagt ccctctttca tggagcgaat ctcatcacct agtgatacta agtctagcac
    69721 tttcatcaat tcatcatcag ttactaagcg attcaaaccg agacaaagat tgtcacgaat
    69781 actgccagat aagactgcat tattttgtga aacccaagcg attttacttc tccattcttt
    69841 taagttaaaa tcatatatac ttgattgctc cattagaata tctcctgaaa gcggtttata
    69901 aaaccgctct aacaaacgca caatcgttga ttttcctgat ccagatggtc caacaaaagc
    69961 aattttttgc cccttgaaaa ttgaacaagt aatatccttt aagacaggtc gattttcatc
    70021 ataaccaaaa tagacatggt taaaattcaa cccttgtcct gataccgatt ttcctccctc
    70081 aaatttttct ttaggaactg caagcaagtt ctccagtgca actgaagatc ccttgctact
    70141 agaataaata gttacaaaat tagctatatt actaatagga ttaagtaatt gaaagaggta
    70201 aatcaaaaac gaaaccaagg ttcccacaga tatatatcct gcgctgaccc gataaccccc
    70261 ataggttagc atcacaacta tagtcgcaaa gataaataag agagcaaacg gggtctcaaa
    70321 agaagtaacc ctatctgatt tcagtgaatt gttttgtacc ctttcaatac aattatccaa
    70381 aacatcctgt acacttttct ctgcttggtt agtcttaatt aattcatgtt cttgaatctt
    70441 ttcagtcaat tgccctgtta aaaatccgat ttcctcctgt aaacgacgac tatacttttc
    70501 actgatattg gaaaggggca agataataaa catcatacaa ggaagagtga tgaataaaag
    70561 tagagaaaga ttccaatcaa gactaaataa gactacaatg gaaccaagta ccataactaa
    70621 actcagaata atatttggga aagtcgtaat taaaaactca cgaatgacac tcatgtcatt
    70681 gacaatggca gaagtcaact ccccactttg gctcttatca aagaaggatt tctctgcata
    70741 aatcaacccc tctatcactt ttttcctgat ttttgctatc ttttttcacc cgattgacta
    70801 aacagatagt aaccaataga agaaaacaag gcttgaccaa taaaaatcaa aaacgattga
    70861 aatactttgg aacctatatt ttcaatagaa ctcccatcta ttaaaccctt taagataagg
    70921 ggaagcaaca aagcaagtag actagacaga acaagtaaga aactccacat aatcacctta
    70981 gtatctactc ttaataattt taatttcata aatactcctt ataatatttc aacggataaa
    71041 gtcgggaata actcaatttg aggataaaat ctaataaatc ttcctataac aaaacgcata
    71101 acatctagga ttttatatac ctgatattat gcgtttttaa gcacaaagac ttcttacaca
    71161 aacttatcta caattagatt ttatttgaca tgttttgcca attcttcttg ggctttttta
    71221 ttggattctt ctttttcttt caaccatttt tctctggctt ttgcatattc gtctgttgtg
    71281 acaatcttat cttgtacttt gaggtattta tatgattcaa cccctttatt accagccaat
    71341 gaataaggtg ctgagaaagg aactgttttt ctcaagctag gcgttccacc taatgaaaca
    71401 tttggaatcg ctagagaact atctatcaac catgcttgaa tatcagcata tttctcataa
    71461 cgtttggctg ggtcttgctc cttattagcc tcttccaaca tttgagtata agtgtcaagt
    71521 ccaactgcct tagccttgtc attggcttca ccagggtcga gtccaagatt ttgtagaacc
    71581 ccaccattct tgacactaaa gatatcaaga taggttgatg gatctaagta gtcaggactc
    71641 caaccaccat tgtaaaggtc gtagtctttc tgaatagcag tctgagcaag gtaacttgag
    71701 ttatcatagt cctctgttga taactgttgg atatcaataa cgacgttctc cgtacctaaa
    71761 gctgcttcaa tagattgctt catggagctt acttcttgaa tccccttctt agaagcttgg
    71821 tcaactgtcg catccaaatg aatagggaat tgaactccct tagcttctag ctctttcttg
    71881 gcctcagcaa atttagcctt ggctttctca ggattgtagt aagggtcttg accatccgca
    71941 aagttgatgc cttgccattc cttaccataa ttattgacca tcttagaggc tactacttca
    72001 ccaaaatctt ttcctttgat acttacaaag gttggaggaa caaccaagtt acgcaaaatc
    72061 ttagtcgctc cgtcttctcc ctgagtttga gccccatagg aggtacgatc ataggcaaag
    72121 ttaatagctt gacggaagtt tttattaaga actgcttcct gagttgattt cttttcaatg
    72181 tcggtcgtct tagaagtaaa tttataagct tgtctatcta ggttaaaatt ccagtaataa
    72241 gacgtagcat cctgcatact gtagatgata tcatctttgt atttttcttt aatcccttca
    72301 aaacttgaac tattcggata gagacgggca tagctatagg ctccgtctgt aaagttacga
    72361 acaagagcat cttggtcact accatcatag taggtcaatt tcacatcgtc tacaaagaca
    72421 tttttagcat cccagtagtt aggatttttc ttgtattcga tgacagattt tgaaacaaaa
    72481 gctttcatca agaaaggtcc actgtacaaa atattagcag ggtctacctt gccaaaatca
    72541 tccccttttg atttcaagaa atctgcattg actgggaaaa gaatggttga ggttgttttt
    72601 gagttccagt aaggttctgg tcgagccaag gtgtattgaa cggtttgatc atcaagagcc
    72661 ttgataccga cagttgaaaa gtcgcttgtt ttaccagtga tatagtcatc caaacctgca
    72721 acagagtcct gcactagata caaggcttct gattttttat cagctgcata ttgcaatcct
    72781 gtcacaaaat cctgggcagt tacaggtgca tattcttctc cctcagaagt aaaccacttg
    72841 gcatccttac gaagtttgta ggtataggtc aaaccatcct gagaaacagt ccaatcttct
    72901 gccaaggatg gcacatagtt cccatattgg tcattttcca tgagaccatc taccagattg
    72961 gtcacaatat cattggttgt tgcgcggttt tctgctagat agttcaaact agatggatca
    73021 cttgaataaa catagttata ggtttttgat gcagtgctag aatttccaca cgcgctcaat
    73081 aaaactcctg tacccaggac aaaacctgcc aaggttagat atttgctctt agactttttc
    73141 atttccagaa cctcctgctt taaatatttg ttttattata caactcttgg tttgtttagt
    73201 caattgtttt ttccaaaaaa tcaaaaaact cattttctat ttttgaaaga taattttagc
    73261 tattttgacg ctaaaaaagg aataagtttc aagttctcct aaaagattgt tcaacttatt
    73321 ccttttattt ataaatgcta ccttacgaaa gcttaaattt tgctcgcagg cgatctgctt
    73381 gggcttttcc tattacctta tctaataaat aggtacgcag actcataacc atataaagtc
    73441 caccccccat ggcaccgaca agagctacat aaaagaagct ccacaaacgt ccacttggtt
    73501 ggaagaaaaa tcctaacagc cactggatgg ttcctattaa cagaaacatg actagggtca
    73561 gcaaactgat taaaatggtt cgcttcaaaa tcaccttgcg cttgacacca gttactttac
    73621 aaatatcccg atacatcaag acgttaggaa tgatgagagc aatggttgtt gaaatcaaag
    73681 gaccataact gtggaagagg gcgatggtag gtagttgcaa gactagcttg gcaatagaac
    73741 catagataaa atagagaacg gccttgcggt tgcggaacat ggcctgaagc attggagaca
    73801 agaccatgta caagcctaaa ataatagact gcaaaactgc aaagacaaat aagcccagag
    73861 ccaaactatc tggcttacca tagaagaccg tataaagagg ttctcctacc ataaccactc
    73921 caaccgttgc tggtagcaag aacataaaga gtagggtgag actgtcctga acgagacgag
    73981 aagccgcttt caagtccccc ttgacatagt tttccgtcaa aagtggcaaa ccaacactcc
    74041 caatcgaaac ccctacagaa atcaaaatca tcgtgatttt attaggattg gctgagaaat
    74101 aagaaaacat gacaaccaag tcctcattgc tgtagttggt aaaccagctc atactattga
    74161 taaaggtcag ctgatccaaa atctggaaga gctggatggc agaccctgtc aggataaaag
    74221 gaatggcttc cttaatggta tcaaccaaga gacgcttact gttaatctta tctcctgttt
    74281 caaagactct tttgagtgaa ccttcttggg caaggaaata aatcaagact gcaaaactgg
    74341 ctaccatacc gacaaaggca gcaaaggttg attgggtaac ggctgctaga taatctcctg
    74401 aaccgagctt cataatgata aaggttgcta ggagcatcca gataacacga atgacctgct
    74461 cagcaatttg gctcatggca taaggtttga ggttattcat cccttggaaa aatcctcgga
    74521 taacactcat agacgggaaa atcaagactc cccaagccaa gctttgcatg attgggatca
    74581 agtctttgcc cacgccagac aagtctgcta gccaaggagc aaagacatac aagactaaag
    74641 caaaaaccag gcctagtcct gtcataaagc ctaagaagct ccgaatcagg gcaaagctat
    74701 gctcttcttc tcgcatggta ttatacttgg caacttgctt ggccaccgca actggaatcc
    74761 ccgctgttga aaccaacaag aaccaagcat agatattgta acccatggta aagagaccat
    74821 ttgccttagc tgcataagcc cccatccaga tgtaccaagg gataatgtaa acagccccga
    74881 gtaggcgact gataaagtta ctagccgtta gccaagcagt cccccgtaac atctgggcct
    74941 gctggtgatt gttttcgtgc gacatagatt cctcattcaa ttttgataac taggaaaaac
    75001 tccttatctt ccattataaa cttttccttg ttacttgtaa atttgcgact ttcggtttac
    75061 aatagaaagt atgataaaaa ttgaaactgt attagatatt ttaaagaaag atggcctttt
    75121 tcgcgaaatt attgaccaag gtcattacca ctacaactac agcaaagttg tttttgatag
    75181 catcagctac gacagccgaa aagtaacaga agacactctt ttttttgcaa aaggtgctgc
    75241 ctttaaaaaa gaataccttc tttctgctat aacacaaggt ttagcttggt atgtagctga
    75301 aaaggactac gaagtcggta tccctgtcat cattgtgaac gatataaaga aagccatgag
    75361 tttgattgcc atggagttct atggtaatcc acaagagaaa ctcaaaattc tcgccttcac
    75421 aggaactaag ggtaagacaa cagcagctta ctttgcttac aacatcctat ctcaacgtta
    75481 cccaaccgcc ctcttatcaa ccatgaatac aactttggat ggcacaactt tctttaaatc
    75541 ttcattctca acacctgaaa atatcgacct ctttgacatg atggctcaag ctgttaagaa
    75601 tggaagaagc catctcgtaa tggaagtctc tagccaagcc tatctagtcc atcgagtcta
    75661 tggactgacc tttgatgtag gagtctttct taacatcact cctgaccata tcggcccgat
    75721 tgaacaccct agctttgaag actatttcta ccacaagcgt ctcttgatgg aaaatagccg
    75781 agcagtcatc attaacagtg acatggacca cttctcagtc ttgaaagaac aggttgaaga
    75841 tcaagaccat gatttctatg gtagccaatt tgataaccaa atcgagaatt ccaaagcctt
    75901 tagcttttca gctacgggta aactcgctgg agattatgat atccaactca ttggcaactt
    75961 caaccaagaa aatgcagttg ctgctggact tgcttgtctc cgtctcggag caagtcttga
    76021 ggacatcaaa aaaggcatcg ctgcaacccg cgttcctggt cgtatggaag tcctcactca
    76081 gaaaaatgga gccaaggtct tcatcgacta tgcccacaat ggggatagtc tgaaaaaact
    76141 catcaatgtg gttgaaactc atcaaaccgg aaagattgct ctggttctgg gatcaacagg
    76201 aaacaaggga gaaagtcgtc gtaaggactt tggcctcctc ctcaatcaac accctgagat
    76261 tcaagtcttt ctgactgctg atgaccctaa ctatgaagac ccaatggcca ttgcagatga
    76321 aattagtagc tacatcaatc atcctgttga aaagattgcg gatcgccaag aagccatcaa
    76381 ggcggcaatg gctatcacaa atcacgaatt agatgcagtt attattgcgg gtaagggagc
    76441 cgattgttac caaatcatcc agggcaagaa agaatcctac ccaggagata cagccgtcgc
    76501 agaaaattat ttataagaat agaaaaaatc aagggaaaat gaaacccttg attttttcct
    76561 attatttagt aaaaacgttt ttcaaacctt caacggcacc ttctacagca ccttttgcgt
    76621 cttctacaac gtcttttgcc ttagcaactg ttttttcaac agctccttca agttctgtct
    76681 tgctgtctcc agtaacttta ccaaaacctt ctttgacagc gcctgttgct tgttccaatt
    76741 tgttttcaag tgacatatga ttgtctcctt tagtttattc cgatatgtgt taccggttac
    76801 atatagttta taccgaatac taaggaaagt caaacaatgt gctcagaaac aagaaatcac
    76861 gctaagtaga aagttaatct ctccttatca aaatcgatag ccaactcata ctttctatct
    76921 tcattttgca caatatagcc taagacaacc aaactgtcca caaagatatc acggcatttc
    76981 tgcataagct ggtctttttt gagaaatttc aacaaaaaag ccgtcatata cttgagggca
    77041 tactcaggat taacatctcc taaaatgtca tagagctcct gctgtttttc tgtcaaagga
    77101 tactgctgtt tgaccttgta aaaataattg gacagggtca ttttaatgcg cgcaaagtcc
    77161 gtcttttcaa ctaaaatagc tgcattgatt tgattgcgca attccgtctc aaaactctgc
    77221 tccaacaagg cttgatagac cggactagct tctctgacaa aaatctcttg atccagttca
    77281 agactatcaa gtgattcaag cgtaggaaaa ttaaggtaat agcgcttatt ttcacgtaga
    77341 atcaagcttg cctttatata ctcttccatg agtttatcaa ctgcaacatc tggaaactga
    77401 gacttaattt cccgtagaat cacatcctca tactggtcca gatagcggat caattctcca
    77461 aaaatggctg tctcgtcaaa cgagatggat taaaaatctg aatcatgaag atccctttct
    77521 ttacattgta acagaggcga tgctgccaac tgactaggat tggtcccagc ttggttcaga
    77581 ggaacaggca gacctagttc tatgtaatac tccctccaaa aatcactaat ctcctgttcc
    77641 ccatctccaa atttcatagg aatagtttca aaaataggta ggatttctgc tatatactgg
    77701 gagcagtaga aagcagctgc atctggatag aaagaagcat tgtagggtgc tccaagatgt
    77761 ctgcaagctc tttccttcac cgactggata tccatttctg ggtaaacata gaggtcgtat
    77821 aaatgattgg actcaaagaa gtctgccggt tcttgacaga caacaccagc ctgtccacta
    77881 gcatgataaa tcatcccatc caaataaatg gcaacatggc tatagttacc tgtggaagtc
    77941 tggatggcct gtcccatgtc tgacccatct ctcacaaaaa tcaaatcgcc attttctaac
    78001 atacttcact cctagaaaaa aaggagccga aactcctttc gatataaggc aaactagact
    78061 ttccgatttt gagctgacac ccaaaatctt acgcattaaa gctttcagtt aattgaggta
    78121 ccacttgttt cttacgtgaa acggcaccag caaggaaggc atgattgttt tcaagtttga
    78181 agttgaaagc cgcttcgacc ttgtccatgt tggcaccaag agccaagatt tctgagtttg
    78241 agttgacgat atctgtaatc atcaagacaa agtcagagta gccgtttgat tcgttggcag
    78301 cttgcattgc agcttcaatt tctgcttggc gttccaaaac ttcagcgatg tcaactgtgt
    78361 tcacttgggc aacacggaca ttatttccgt tgagttcaaa agtcttagca tcgatgtcaa
    78421 tcaattcttc agcagatttg ctagccaagt tggtaccagc tttcaacatt gccaaaccat
    78481 attcttccaa gttcacacca gccaattcag ccaattcagg agcaatgatt ttatctgttg
    78541 ggtgtgttgt tggtgatttc aaaagaaggg tatctgaaat caaacctgaa agcatcaaac
    78601 ctgcaatctc tttaggcaca gctacaccat gttctttgaa catacggtaa acgattgaag
    78661 acgctgatcc aactggctcc aaacgcatgt aaagtgggct tgcagtttca aagttagcca
    78721 cacggtggtg gtctacaaca ccgtaaactt ctacttcagc gatatctgat acagattgtt
    78781 ggaattcatt gtggtcagtc aagataactt gctctgcccc ctctgctttg gcagaagtga
    78841 taacacgtgg tgcttccaca ccaaaatagt tcaagacaaa ggctgtttct tcatttggag
    78901 ttccaagggc aacagcttcc gtatccaaac cgtaagcttc ttttgcaagg taggcaaaag
    78961 ctacagatga tccgatggca tctgagtctg gattttggtg accaaatact agaatcttgg
    79021 acatgataat acctcatttt gtttattttc tttattgtag catttttttc gctttttgac
    79081 aaaggtaaga ggagtcaaag gactccccac gattcttcaa aataactgag taaatttcta
    79141 tcttgatttt cagataaaaa ttcttccttc tgtggcctct tcttacgctt gagaagagct
    79201 tcagccgaca tggcttcttc cttactggca aaaccttgag catagataag tttgactggc
    79261 aagcgtgctc gtgtatattt ggctcccttc ccactattgt ggatagcgag gcgtcttctc
    79321 acatcagtcg tatagcctat atagtaggat ccatcacgac actccagaac gtacatataa
    79381 gccttatgat ccataataaa tctcttcgat ttcgggcgta taagagccat catcattgtg
    79441 gacaatcaaa ggaggtaaga ccttaaagcc acttgttgag ccatccttga tcgcctcaat
    79501 caaaagcata ttggcttcct tttctctttt tggataaaca aactgcaggc gcttaggggc
    79561 tagattatgt cgttttaacg tatccaaaat atccagaagt cgatcaggac gatgaaccat
    79621 ggccaaacgc ccattagact tgagaatact ctgggcacta tgacagattt cttccaaatt
    79681 agtcgtgatt tcgtgtcgag ccaagagata atgttcactc tcgttcagat tagaatgagg
    79741 atccaccttg aaatagggtg gattacacaa aatcatatcc accttactcc cctgaatgtg
    79801 agcaggcata tttttcaaat catcgcagat gacctgcatt tgctcctcta atccattcaa
    79861 acggacagag cgttcagcca tatccgccaa acgctcctga atctcaacag acaatatctg
    79921 tgcttgagta cgagtgctag caaaaagccc cactgctcca ttcccagcac agaaatctac
    79981 aatcaacccc ttcttaggaa aacgtggaaa tcgtgataag agaacactat ccaccgaata
    80041 gctaaaaacc tctctatttt gaatgatttt gatatctgtc gaaaagagct ggttaatgcg
    80101 ctctcctgat tttaataatt gttcttcttc catggtccta ttatagcaaa tttatattaa
    80161 cattacaaaa aatataaaac tctaaactac ttcttctttt ttaaatagtg cagggcttct
    80221 ccagtccaga ttggtagcat tcgtcgaaag ggagcaaaac cgtagttaaa gcggtcgctt
    80281 gaaaagcgtc tccgtctagg aaactggtac ttttcttcct ccaaagtgcg gatagaaaga
    80341 ctggctttcc ccgtaaattc atctaaatcc actacctgaa cttgaacctc ttcatcgact
    80401 ttcaaggttt catgaatatt ttcaataaat cctgtccgaa tttctgaaat gtgaatcagc
    80461 cccgtatcac ccgtctctaa ctcaacaaag gcaccgtagg gctgaatccc tgtaatacgc
    80521 ccctttagct tatcaccgat tttcatctta gtcctcgatt tcaatagttt caattacaac
    80581 atcttcaact ggcttgtcca tagctcctgt ctcaacagca gcaatggcat ccaagacagc
    80641 gtaagatgct tcatcagcta actgaccaaa aaccgtgtga cggcggtcta ggtgaggtgt
    80701 cccaccttga ttggcataga tttctgcaat cggttctggc caaccaccac gagtaatttc
    80761 tttcttagaa taaggtaggt gttggttttg cacgataaag aactggctgc cgttggtatt
    80821 tggaccagca tttgccatgg aaagagcacc acggatattg taaagctctt ctgagaattc
    80881 atcctcaaaa gattcgccgt agattgactc gccacccata ccagttccag ttgggtctcc
    80941 accttggatc ataaagtcct tgataatacg gtggaaaatg acaccatcat agtagccatc
    81001 ttttgaaaga gatacaaagt tagccactgt tttaggagca tgttcaggga aaagcttgat
    81061 acgtaagtct ccgtgattgg tcttaatagt cgcaagagga ccttctactg tttcaatgtc
    81121 tacttgtgga aaatgcaatt ctttttctac cataccaaat acttctaagg catcaaaaat
    81181 gccatcttct tctaatgttt ttgtaatata atctgctttt tctttgattt tatcatgaga
    81241 aattcccatg gcaacgctga ttccagcata atcaaagagt tccaagtcgt tgagaccatc
    81301 tccaaaaacc atgaccttct ctggtttcaa gccaaggtgt tccacaacct tttccacccc
    81361 cgtcgctttg gagcctgaaa tcggcacaat atcagaggaa tgttgatgcc aacgaaccat
    81421 gcgaagtttg tctgagagac tgtcaggcaa gtgcaagtca tctcccttat cttcaaaagt
    81481 ccacatctga tagatatctt ctttttcatg gaaatcggga tctacatcta agtcgggata
    81541 aattggattg atagcttcac tcatcatatc ggtgcgagtc gacaacttgg catcatgact
    81601 cccaaccaag ccatactcaa ttccttcttg cttagcccaa gagatatact cctcaacatc
    81661 tgactttcca atctgatgct gataaatgac ctgacctttt ttatcttcga tataagcccc
    81721 attcaaagtt acaaaaaagt caggcttgag atcacgaatc tctggaacaa caccaaaaat
    81781 gccacgtcca gaggcgattc ctgttaaaat tcctttttca cgcaactgtt taaaaacagt
    81841 gggaattgta gttggaataa accctgtctt tgaattccgc aatgtatcat caatatcaaa
    81901 aaagacaatc ttgatcttct ttgccttgta tcttaatttc gcgtccatct cactacctct
    81961 ttcaatctaa ctctttccat tatatcataa agtaggcaaa tcccctattt tcaaaaagtt
    82021 tatcattttt attttaattt cttggatgag aaaagagaca tatttatgaa aaagctccat
    82081 cgtgcttgta atgtgttctc ttgttttcaa actcgtaaaa agggagccac tgagcctaac
    82141 tcgctctctc atttcaaagc ttgtgaaaaa agacccgttg gggtcttaat tcgctttctt
    82201 gttttcaagc tcatgaaaaa gagacccaac cgggtctttt ctttaatctt cgtttacgaa
    82261 aggcatcaaa gccattacgc gagcgcgttt gatagctgtt gttactttac gttggttttt
    82321 agctgaagtt cctgttacac gacgaggaag gattttccca cgttctgaaa cgaaacggct
    82381 aagaagctca gtatctttgt aatcaacata ttcaatttta tttgctgcga tgtaatcaac
    82441 ttttttacgg cgtttgaatc cgccacgacg ttgttgagcc atgttttttc tcctttataa
    82501 gtttagttgt ccattagaat ggtaaatcat catctgaaat atccaatggg tttgttgctc
    82561 caaatggatt ttcattacgt gaaaagtctg gtactgaatt tgtaggtgct gaatagtttg
    82621 cagttggtgc agagtaagct ccacctgtgt gaccctcacg cacactacgg ctttccaaca
    82681 tttggaaatt ctcagccacg acctctgtca cgtagacacg ttgtccttgc tggttatcgt
    82741 aactacgagt ctggatacga cctgtcaccc cgataagtga gcctttttta gcccagttag
    82801 caagattttc agcctgttgg cgccacataa cgacattgat aaaatcagcc tcacgttcac
    82861 cattttgact cttaaatgta cggtttactg caagagtaaa agtcgcaact gctacatttg
    82921 atggggtata acgcaactca gcgtcacgtg tcatacgccc tacaagtaca acattgttaa
    82981 tcatagttta ccttcttacg cgtcaatttt gacgatcatg tgacgaagaa tgtcagcgtt
    83041 gatttttgaa agacggtcaa actctttaag agctgcatcg tcatttgctt caacgttaac
    83101 gatgtggtaa agtccttcac ggaaatcttg gatttcgtat gcaagacgac gtttttccca
    83161 agtttttgat tcaacaacag ttgcaccgtt gtcagtcaaa atagagtcaa aacgtgctac
    83221 caaagcgttt ttagcttctt cttcaatgtt tggacgaatg atataaagaa tttcgtattt
    83281 agccattgat atgttcctcc ttttggtcta atgaccccaa gactttgcaa ggggtaagtg
    83341 aggttcgctc acaataaact attatactag aaaaaatttt tttacgcaag taaaaacact
    83401 agaattcgaa aaaacgccac atgggcgttt tcctgttctt atggtttgat acggtgcaac
    83461 atacgtggga atggaatagc ttcacggata tgttttgttc ctgctgcgaa ggttaccata
    83521 cgttcgatac cgataccaaa tcctccgtgt ggaactgtac cgtatttacg aaggtcaagg
    83581 tagaattcat attctgtacg atccatgcca agttcatcca tcttagcgac aagggcatcg
    83641 taatcttcct cacgcataga cccaccgata atttctccat agccttctgg agcaagcaag
    83701 tctgcacaaa gcacgcgctc tggatttcca ggaactggtt tcatgtagaa ggccttgatg
    83761 gctgctggat agttcatgac aaatgttggc acaccaaagt ggtttgaaat ccaagtttcg
    83821 tgtggtgacc caaagtcatc accatgctca agatgctcgt agtcagcatc ttcatcattt
    83881 tcatgctctt gcaagaggtc aatggcttga tcgtaagtga tacgtttgaa tggctctgca
    83941 atgtagcgtt tcaagagttc tgtatcacgt tccaaggttt ccaaggcttg aggcgcgcgg
    84001 tcaagaacac cttgtagaag agctttcaca taagcttctt gcaagtcaag cgactcatca
    84061 tgtgtcaagt atgagtactc agcatccatc atccagaact cagtcaagtg acggcgtgtt
    84121 tttgattttt cagcacggaa aactggacca aagtcaaaga cacgaccaag agccatagcc
    84181 cctgcttcta ggtaaagttg acctgattgg ctcaagtagg ctggcgttcc gaagtagtca
    84241 gtttcaaaga gttctgtaga atcttctgcc gcatttcctg aaagaattgg gctgtcaaac
    84301 ttcataaaac cgttcttgtc aaagaactca taagttgcat agataatagc gttacggatt
    84361 tgcaacacag ctacttgctt acgagagcgt agccacaagt gacggttatc catcaaaaag
    84421 tctgttccgt gttcttttgg tgtgattggg tagtcttgag attcaccgat cacttcgatg
    84481 tctgtgatgt ccaactcata gccaaattta gaacgttcgt cctctttgac aatacctgtc
    84541 acataaacag acgtttcttg gctcaagcgt ttgataacat caaacttctc aagtcccact
    84601 tcttcaccaa atttttcgac aaagtttggt ttaaaagcca caccttgaaa gaaggctgtt
    84661 ccatcacgca attgtaagaa agcgattttc ccttttcctg atttattggc aacccaagcg
    84721 ccaatcgtca cttcctgacc aacatagtct tttacgtcaa taatcgttac acgttttgtc
    84781 attatttttc cttttctttt ttattcttta tggcaaacca cctctatatt gttcccatcc
    84841 aggtcaatca taaaagcagc atagtaaatc ggacgctcac ttcgataacc aggagcccca
    84901 ttgtctcgcc cacctgcctc taagccagcc tcataacaag cctaaacttc ttccttattt
    84961 tctgctaaaa aagcaaaatg aacaggatct tgtgttccct gagtcagcca aaaatcacca
    85021 ccaggatgag ggctgttcgg ggatagaaaa ctaattagag aactagtctt aaaagccaat
    85081 ttatagtcca aaggagcgag aaaactccta taaaatcctt ctgaaatttg taaatccttt
    85141 accttaatct caaaatgatc aatcattctc actacccata aatgctttca agcgttcgac
    85201 tgcttcttta agcgtgtcta ggtctgtcgc atagctgagg cggacatttt ctggtgctcc
    85261 aaatccagct cctgttacca aggccacttc ggattcttct aagatagcag ttgtaaagtc
    85321 tgtcacatcc gtgtagcctt tcatctccat ggcctttttg acatttggga agagatagaa
    85381 ggccccttgc ggtttgacca cttcaaatcc tggcacctct gcaaggaggg gatagatggt
    85441 attaagacgt tcctcaaagg cctgacgcat gctttctaca gtatcttgct cacctgatag
    85501 agcctcaact gctgcatatt gggctactgc tgacggattc gaagttgttt gacctgcaat
    85561 cttggacatg gcagcgataa tgtctgcttc tccaacggca taaccaatcc gccaaccagt
    85621 catggcatag gttttagaca caccattgat gaccactgtt tgcttgcgaa tcgcttccga
    85681 taggctagaa atcggtgtga actcatgacc attataaacc aagcggccat agatatcgtc
    85741 tgctaggatg agaatatcat tttctacagc ccagtttcca attgccaaga gttcctcacg
    85801 ggtgtaaatc atacctgtgg gattagatgg cgaattcagc accaaaacct tggtcttgtc
    85861 agtgcgagct acttctaact gctctacggt caccttaaag tgattgtctt ccttagcaga
    85921 aacaaagacg ggaacgcctt ctgccatctt gacctgatct ccatagctaa cccagtatgg
    85981 ggttgggatg atgacttcat cacctggatt gaccacagcc ataaagaagg tatagagaga
    86041 atatttggct cccgcagcga ctgtcacttg atttgacgct acagaatagc cgtaaaagcg
    86101 ctcaaagtag ctattgacca ccgccttaag ctctggcaga cctgaggtta ctgtataaaa
    86161 agaagcacgc ccatctcgaa tcgatgcaat ggcggcatct tggatatttt tgggagtagt
    86221 gaaatctggc tcacccaagg ttagagacaa aatatctcta ccctcagcct tcagtgcttt
    86281 ggcacgggct ccagcagcca aagtcacact ttcttccatt tctaaaacac ggttggataa
    86341 tttcataggc cctccttgtt gaccaatgct cctgtttcaa aatctactag ataaaaatca
    86401 gatcctgact tgacttccca gattggctta tcttgataac gaccaaagat aatcttgtca
    86461 atttcgccag ctcccttttc cttagaaacc gtttctgctt tttcttgtga aacaccctga
    86521 tttagctgat aaacgtaaat cttatgatca tctttaccaa tcaggacagc aagcgcttct
    86581 tgctgtttat tacgaccaag aacgctgtaa taagattcca agccattgta taaatcaacc
    86641 tgatcgacct gctctaatcc tgcatactgc tgagctaatt tttctccttc acttttagct
    86701 gtttgatagg gtttcatgct aagagaaacc atatacagaa aggaagcact gataaccaca
    86761 aacaaaatcg tcatccctag accatactgc cacagtagat tattttttgc tttgttttgt
    86821 ctttttttca ctcgtctatt ttaccatcta ttaagcttta ttacaagtga atataagaat
    86881 actcttcgaa aatctcttca aaccacgtca gctttatctg caacctcaaa gctgtgcttt
    86941 gagcaaccaa ttctatttct cccttcaaac aaaaccgatt tttaaagtga aacagttctt
    87001 actttttcag tcacaaatga ttagagtttc cgaaatttta caattttcaa ataaactctg
    87061 agcaaatttc ttgcaagttc ttttgttttg ttgtaatata ttttataaca acgagagagt
    87121 tctcgaaatt ttaagaaaaa ggagacacat catgtctaaa aaagtattat ttatcgtcgg
    87181 atcactacgt caaggttctt tcaaccacca aatggcgctc gaagctgaga aagcacttgc
    87241 tagtaaagcg gaagttagct accttgatta ttcagccctt cctctcttca gccaagattt
    87301 ggaagtccca acacatccag ctgtagctgc cgctcgtgaa gcagttctcg ttgcggatgc
    87361 tatctggatt ttctctccag tctacaactt ctctatccct ggtacagtga aaaacttgct
    87421 tgactggcta tctcgtgccc ttgacttgtc tgatacacgt ggcgtttctg cccttcaaga
    87481 caagtttgtc acagtatcat ctgtagccaa tgcagggcac gatcaacttt tcgctatcta
    87541 caaagacctc ttgccattta tccgtacaca aggcgttggt gatttcactg ctgcacgtgt
    87601 taatgactct gcctgggcag acggaaaatt ggttcttgaa gaaacagtcc taaactcact
    87661 tgaaaaacaa gctcaagact tggtcgaagc gattcagtaa aaaatagaaa attttagaaa
    87721 gtctaaatca attatagcca cctaataggg tggcttttta tttctcaatc aagattttca
    87781 gacaaacatc agccatccaa aaaaaccttg agcgttacca ctcaaggttt ttagcagtct
    87841 tttccatcat aggaaaatca ttctaagaat attctttcat tcgagatcta tcacttatca
    87901 tcttctttcg agaaattagt gactgctttt ggctgattaa tcttcttttc ttcgtcctac
    87961 atataggctc aatagaatac cgctacctaa aagaacagag atataatcag attggcttcc
    88021 agtttcaggt aatttgtccc cacggttttc tttacctgta gttggtgcta ctgggttagc
    88081 atttactgga gttgctggtt gagccggtgt tggtactact ggttgttctg gaaccgctgg
    88141 tactggttta accggtactt ctggtgtcgg cacatttggt gttggaggaa ctggtttgtc
    88201 atttgatggt gttactggtt tgtcttggca tccacatttt ccatctttac cgtctttgcc
    88261 gtctcgacca tcacgtccat ctctaccatc tttgccatct ttaataactg tttttgtcac
    88321 agttccatca gaattgatga ttgtgattgt atgactacca tcaccattat cttcaacaga
    88381 aacttttggt gatttaccat ctttaccgtc tttaatcacc atttctgtct tacttccatc
    88441 tggattagtg attgtaacaa cgtgagttcc atcgttatta tttttaacag ttacagttgg
    88501 tgaaacgcta tctttgccgt ctttaccatc tttgataata gatttgtatt cacgaccatc
    88561 agaatctacg attgttaatg tatgagttcc atctccgtta tcaacgatgt tcgcttttgg
    88621 tgatttacca tcaaagattg tagttgtcgt tcctttacca tcagcacctg tcactttaat
    88681 agtgtgtgaa ccatcgttgt tatcaataac ttcaagtttt ggttctctac catcacgaac
    88741 tgtagttgtt gtagttgttc cgtctgagtt cacaactgtg atagtgtgag ttccatctcc
    88801 attatccaca accttagcag ttggtgattt accgtcacga actgtggttt cagaaacagt
    88861 accattaccg ttttccacac gaatagtgta agtaccatct tggttatctc taactgttgc
    88921 tactggtgat ttaccatctg taatgattgt ttcagtagtt gttccgtcac catttagaac
    88981 agagatctta tgagttccat tttgttcatc agttatagtc acttttggtg atttaccatc
    89041 acgaactgtg gtttcagttg tcacaccttc tggatttgta ataacgattg tatgacttcc
    89101 gtctccatta tcacgaacag atgcggttgg agtacgtccg tcaacaccgt cacgtccatt
    89161 cttaacaaca aactcattct tagttccgtc tgggttagtg attgttactg tgtggcttcc
    89221 atctggattt tcagtagttg ttgctgttgc agctttacca tctttaccat ctttgatgat
    89281 agcgttggta acattgccgt ctccatccgt cactttaact gtgtgtgttc catcgttgtt
    89341 atccgttact tcaactttag gagtcttacc gtctttaccg tttttaacaa cagtttcttt
    89401 agttgaacca tctggatttg tcaccgtaat tgtgtggctt ccatctgggt tttctgttgt
    89461 agtgatattc gcagttttac cgtctttacc atctttaaca acagttgttg attcagaacc
    89521 atcaggattt tgaactgtga tagtgtgtgt tccatctcca ttatcttttg tagtaatagt
    89581 tggagctgaa ccatcacgtc catctatacc gttataaata tctttactat ttaatacttt
    89641 atcgacacct ccgtcgtata ccccattgtc attaacatca tcataaactg taacacggat
    89701 accgttacgc gttggagttg cagcagcatc tgtatcgcgt ctaattcttg aaggtgaagt
    89761 aatatcttct actttgattt tcggtgcacg gccatcttta ccattcttac catcttttac
    89821 agtgaaggtt actggatctt tacctgatgt tgtgatagtt acaacagtgc tttggccatc
    89881 ttgtccacgt tgagtagtga ttgtaggagt ttgtccatcc tgaccggttg caccagtttc
    89941 tcccttagca ccatcttgaa caaagactgt agttggttgt gaaccatcat ggttatcaac
    90001 agtgatttct acacctttat gccctgcttc atctttacga acagctgtaa ctgtaggtga
    90061 ttttccatct actccatctc taattaccgc aagtggtttt tctggattta atggttgtcc
    90121 tgggttagct ggatcttctt ggtaaacttt agtttcttta ccatccttga cagtaagcaa
    90181 tgatttacca tctcgtccgt ccgcgccttt agcaccatct ttaatcattt ctgaacctag
    90241 aagttcatca gttcctggtg tatatttgcc gtcattgttt tcatctgtat agaatgtcac
    90301 aattgtatga gatggatttc cgttttttcc ttggacacga agtaaatcaa cttttggagt
    90361 tttaccgttc agaccatttt ctccgtcctt aacatttact gtaactggat ctttacctgg
    90421 aacagtgaat gtaatgtcag tactatggcc atctttacct ggagttacag ttacttctgg
    90481 agtcttacca tcttctccgc gttcaccttt gtcaccctta gggcctttga tgttgccctc
    90541 tttatcccag ttgccgttat tcttaacgaa gacgtcgcct gtttctgtat taacgtattt
    90601 atcgccgtct ttaccttgat gtgcttctgg gttagctttg ccgttcaaca cgtctttacc
    90661 gtcacgtcca tcacgaccta ctgcgccatc cgcaccttta gctccttgcg ctccagttag
    90721 gccgcgttcg ccttggtctc ctttttcgcc tttagcacca tctgcacctt tgtccccttt
    90781 agggcctttg atgttgcctt ctttatccca gtttccattg tttttaacat agacatcacc
    90841 ggtttcggta ttaatatatt tatctccatt tttaccttgg tttggttgtg gatttacttt
    90901 tccgtttaat acatctttac catcacgacc tgcttgtcct gtagctccat cacggatcgt
    90961 agttgtcaca tctggacttc ctggattatg aaccgttaat gtatgtgtgc cgttttgccc
    91021 ctcagttatt gttactgttg gggttttccc atcagcacct ttttgtccat cctctacaaa
    91081 tgttgtttgt ggacgacctc ctactggtgt aattgttact aatacaccat ttttaccatt
    91141 ttgaacactt cgtgtcgctg taattgttgg tgattgtcca ttagtaccat ttcttccatc
    91201 agtgatagtt gctaatggtt ggtttggatt aagtggttgt cctggtctag ccggatcctc
    91261 tacatagact tttgtttcag ttccattttt aacagcaatt agagattttc catctttacc
    91321 tggagttcct ggattacctt gttctccttt tggtccttgt ggtcccgctg gtcctctttg
    91381 tccatctgcg ccttttggtc cttgagctcc atcacgacct tgaagacctt gttcaccttt
    91441 ggcaccatct gcaataataa cttcttttaa tttcttatca gaagcatcta attcattatt
    91501 tccattttga tcataataga agataacagt tgttgtctta tctgcttcat ttcgttgagt
    91561 cgcaactaat ggacttgcgc catcgaaacc atctcttaca acagtacttg caacattacc
    91621 tctaccgtcg ttaatagtga tagtatgagt gccgtcattt ttattatctt taacggttac
    91681 ggttggagtt acaccgtcac gacctgcctg accttgcgct ccagtcaggc cgcgttcgcc
    91741 ttggactcct ttttcacctt tagcaccatc tttaatagca attttttgaa caagttcgtc
    91801 tacgccctca gtataaacac cgtttccatc gttatcaaga tagaaagtga ggttatttgt
    91861 atcaccgact ttattttgat caacacgtgg ttttactgta tcgattagat ctttagccac
    91921 accaatttgc ataatacgtg gcttaacttc tttaataact gaattactaa ttggcaatcc
    91981 taggattgtt tcgttaccca attgatgaac tttatagatg atttgacgtt gtcctttttc
    92041 accttctcga actaatctag tttgaccttc tggtaactta ctagttggaa gatagacagt
    92101 ttggaagtca atgtcttctg aaacagtctt attattagta ccaccatttg gatttgcatc
    92161 caagaggagt ggtttttctc tgaagtaata gttagagtta ctatatggat cattactagt
    92221 tgcagatcct gattcccctt gacctacatt aaaagtaaca ggtcttaatc gaacagacag
    92281 atcaccatta gggttggcta taggtaaact aaatctaata gtttgattac tgtttgtttc
    92341 aacagcagat gttaaactgt agcttgaatg agatacaaaa tttgcaccct ttcttatatc
    92401 tttagtttga tctcttaatc tgtttgttga aatagttgca cgagatggtt ctccaaatcc
    92461 attccctttg tctaagagaa agttattatt aacgaactca cctggaccag aatatgcaat
    92521 tgagaattct actctatttc caactctagt tgttgttaca tcaaaatgaa tcgggtttcc
    92581 accacgtgaa ttcccattac cacggaaagt atgagaccct ctgctaatat cagtgaaaac
    92641 agtattattt cctagattag ttactagttt gttcgttgga gcaggtgctg ctctaaaacc
    92701 actatacccc ttatccaagt cttctttacg gatagctgga ttttggcgag catcagaaag
    92761 gctcaaacct ggtttcaaga tttcattaat agatgctgga gctgaagttg tttctacttt
    92821 ggcagctgtg ctagttggca aaacagcact atcaacagct gaacgatcag ttgttgcagc
    92881 tggattagtc tcttccttcg cttcaactat attagctttc ttcgctacag gagtttctga
    92941 tacagttcct ttgttagagt tagaacgaag ttctagacca ataatagatg attgaataga
    93001 tgactctgct gctgataatt cagcttcaga tgcatctgct ttcccaagca agctttgacc
    93061 agcttggata cttgtttgca agttagcagc acttgcttct gtatataact tgctttctaa
    93121 ctttttagca cgcgaaagag ccgttaacaa ttttgacttg tcaatagcat cttgatgcgt
    93181 tacttcctct tttttgtctt ttgcttcttc aactttttct gctggtttag taacttctcc
    93241 agttttaact ggagtcgttt ctactggatt agctacagtt ggagctgcat aggttttctc
    93301 tttattagac gcagaaacct ctgctagttt agtagctgct tctcccctac caacagaaat
    93361 actattggta gtttcttgtt tgttttcttc cgcttgtact gtttggacac tagctgctgc
    93421 acctaatacc aaagcggtac cgagcaagac actaactgca ccaaagtaat acttacgaat
    93481 agaataacgt tgttgcatgc tataccagtc aaatgatttt ttatgtgaat gtttcatttt
    93541 aaactcctag atagtatttt atagtttaca atgtacaact atttgaggca ttaatcaata
    93601 ttttctgaac aattaatata ttctgttttt gcacttaaaa gccacttata ttattctaat
    93661 ttttccgatt actaacgaca attttcttgc tctaattttt ttatactact tagacaaaaa
    93721 aagatataat gaattatgga gaaaataccc gtatgagaaa ccttttatcc acaaaagttc
    93781 aaagacaatt acgcttaatg gaaaacctaa ttcagaatcg taattggatg aaattacatg
    93841 aactagccga aaaattagga tgcacagaac gaatcttaaa aagtgattta aatgaattac
    93901 gtattgcctt tccatctatt aacatccaat cttctgttaa cggaatcatg atagatttag
    93961 aagttaacac tagtgtagaa gatatttatc aatattttct tgctaattct caatcttttc
    94021 aattactaga gtatatgttc ttcaatgagg ggctacctat ttatcgaaca atagaaaatc
    94081 tttactttag tagtgccaac ctctatcgac tgggcagaaa tattacaaag gttctttcat
    94141 ctcagtttca aattgaatta tcttttactc catccgagat acgtggaaat gagatcgata
    94201 ttcgttactt ttttgcccaa tacttttctg agcgctatta tttcctagat tggccttttc
    94261 ctgaccttcc tgaggaagat ttaacagagt ttgctgactt cttctataaa atcacgaatt
    94321 atccaatgcg attttcaatt tatagaatgt acaaactgat gatagctatc agtatccaca
    94381 gggttaaaaa tggtcacttc attgacctcc ccaaccactt ttacaaagaa tattatccgc
    94441 ttttaaagag cattccaaat ttccaggaga cacttgctta tttctctaaa cattttgggc
    94501 ttgaaatgac tccagataca atcgctcaaa tttttatttc ttttcttcag aatgatattt
    94561 tcctagatcc tcaagaattc ttcaactctt tagaagataa cagtcaagca agatactctt
    94621 accaattact tagtcaaata ttagaacgcc tatcaaaaca atataagatt acttttacta
    94681 accacgatga gctgatttgg catttacaca acactgcttt ctttgaaaga caggaaatct
    94741 tttctacccc aatcttattt gaacaaaaag cattgacgat taaaaaattt gaagtttact
    94801 tcccagactt tatgggaagt gcgcgtcaag aattggctca ataccgtcag gcaattggac
    94861 agcatgacca tcctgaacag ttggaacact tgatgtacac catcttaacc catgctgaaa
    94921 acctctctac tcagttgtta gaaaatcgac cacctatcaa ggttttgatt atcagtaact
    94981 ttgaccatgc tatatccctt acctttgttg atatgctttc ctattactgt aataaccgct
    95041 ttaccttcga tatttgggat gaattaaaaa caagtcctga gattttaaat cagacagatt
    95101 acgatatcat cgtgtctaat ttctatattc cagggattac caagaagttt atttgccgaa
    95161 atcatctgtc aatcataaat ttggttaatc atcttaacac cttatcaaat gagattcatt
    95221 tgtccaatac tttataagtt atcaaaaaag tcagcataat cgtgctgact tttctcttat
    95281 ctgatttcta tacttccttt acaaaaacca atccctgtgg ttgtgacaaa tcttctcggt
    95341 aaacaaatcc agcaaagttc aagcgacgtg cttcccccac agtttgtact tgattttcta
    95401 ttaaagctgt tagaaaggcc ccgcgcgctt tcttggagat agttgagtga atcttcagct
    95461 gaccgcctct atcctccatg aatttgaagg tcaccatctt tgctctgatt tccttagaaa
    95521 atacagtctc aaactctgat gacaagagag agaaaatcac ttcttccttc ttcagagctt
    95581 catcatagac tgccttccaa tggctcttca aagtcttacc agcgactttt aatttcatca
    95641 aaaaatccaa acggtgagga gccatgggtg acaaggctgg aacaacaccg tacaaagccg
    95701 aggtaatgaa gacatgattt tcaagataat cttgttccgc ctcggtcagc ttatctctct
    95761 taatgttgcg gtacataagc ccatcaaaaa gtttcaaggc tggatagtgt tgagcagttt
    95821 gccttttcaa agcttggata ttttgaaatt cttccgccgc tttctcagct gataccttgt
    95881 agaaactctc caattgactg gcagaataga gagccaaggc atcaagcacg gtctgacttt
    95941 ctggttttaa aggaattgcc tcgatacttg gcaagtctgt gttcatttct tttgctgttg
    96001 ggattaaaat tttcatattg atagtgtagc atatttttta gccacaacca agaaattcat
    96061 ttgaaaaacc tcggtttgac cgaggttttt ctatttattt gggccatcct aaccagacag
    96121 ccacgagaac aagggctgtg ccagctaaac ttgttaagat agataagaat ttatcttttt
    96181 tctccttgaa ctgagaaaaa cctatcttca aagcgagcag tccgagtagc attgaagcaa
    96241 ccatcaaata aaaacccatt tctttgtcct ccattagtct taatttactc tattataaca
    96301 tatactttct gaaaaaacct atttttaccg tagcttaaag gtcttgagat aattgtcttt
    96361 tcctacttga ccttcgaagg ttttaccatt ttcaaggtaa ggaaggtcat cggatactga
    96421 agccttgacc ttgtatatct tgccatcaac tttaaagaag tagacagtgt ctcccttgat
    96481 aacagctgat ttgaggtctg ctactactcc cttgatgctt tctgtcgttg cattgtcaat
    96541 ttcaaggtcg tttttattgg catacttgct gagcatctct tccactgtag tagcaacgat
    96601 aacattttgg tactcgactg cgtctaccag ggcgtactct ttgaccaagc cagcattgtc
    96661 cttcaagccc atgatgtaga gaggcttgtc attgaggttg atgaggattg ggaaggttgc
    96721 tttgtaggat ttctcctgaa cagcaccttc tgctgattca cgggctgatt cttctgtcgc
    96781 agaagccaag ctatacttag tgatttctcc tgttcgcata ttttcaagga tgaaaccaag
    96841 attactctca tccgcattag ccgacgtcac acctgtgtag agatagatgt cattaccgat
    96901 agacaagtaa ttatagccat tggtagtctg ggtcacgttt ttcttggaaa tcatggcatt
    96961 caagaaaccg tccttgtact tgccgttgta gttgatttgc tcaatggttt cctctgctgg
    97021 atagatcctg tccacccatt ctggaacatc tgataagctg tattccttgg tttctccatt
    97081 tgtagcatcc aagataatga ctgaagcagg acgaggaaca gcaagtccaa attgcttttg
    97141 gtaaaccgtt gctacataga aaggattgcc ctcatcgtcc acctcaaaag atggagtttt
    97201 aaagattttg gtcgggtact tcaagcgcag gtgacgtttg acatcacggt taaaatactc
    97261 cgagtctgaa tacttgattg gtgtcttcaa gtccaccaaa tccgcatttc cagttaccat
    97321 gtccacctta atatactcac cgattccctt ggcttgattg ttaaaccatt tgatagggtc
    97381 tgcatattct agtggtgtga cccgataagg tttcccatca attgtcaatt gggtataggt
    97441 atctgccgct acgtattgcg acaccttatc ggttagggaa cccaagtagc ggtctccaat
    97501 tttttcagca gtacttctat ctaggatagg aaccttactg gtgtcactct taggaaattc
    97561 agtaaagtct ttttccgtaa ctgtgactac attggcataa tttttagcct gaaacatgct
    97621 ggaagttacc aaggaaacca aagctgccaa gagaagaatt cctccaatcg aagctaacag
    97681 aattttccct aaccgattga ttttgaaacc ctcaagattt aaggcagctt ccgccttacc
    97741 gtggcgcaca tgaaccgttt tgacaaggtt tatccccttg ccaaagccaa ataagattgc
    97801 cacaactaac aaatgcccac agaggaagaa gagaaattcc cagctggtca ggttaagggg
    97861 cggtaaaaag atataccagg tcgttgcgat aaaaataagt tcaaagacta ttcgtttcat
    97921 ttgctttcct cctaaatgat tcgtccttcc aagtgatcca gctcatgctg gcaaatctga
    97981 gctgggaagc ctgtcaaggt aatggtctgt tcctgccact tgctgtcacg ataggcaagc
    98041 cttatggttt cataacgctt agttgatctc acacctacca aggacaaaca gccttcttct
    98101 gcctcataag atccttcaaa ggacagaagc actgggttaa acatgaccac gggaaccaag
    98161 ccaagattaa agataatcac gcgcttctgc accccaatca tattggcagc tagaccaaca
    98221 caggtatcac gatttgctaa gagtgtatcc tgcaaatctc tggcaagata aaggtcctcc
    98281 tgacttgccg gctgagacac ttgagataaa aataagatat ccttcacaat tttcttttcc
    98341 acttcctcac actcctcttg ctttttacta tattatagca attatagcac aaaagccgat
    98401 aactgcaaac cctttccctc aactgtagca aaaagccatc cgaagatgac ttttttgcta
    98461 tttaatttct gtataagtta cttccaatcc acgcttaaca gctggacgat tggcaatttt
    98521 ttctgcccat tttactagat tttgataact tgaggcatcc aagaattttg cagaaccttg
    98581 gtaaagattt ccttgaacta actgtccata ccaagaccag atagcaatat ctgcaatcgt
    98641 atagtcattg cctgcaatat aaggtttctg agccaattcc ttatccaata aatccaactg
    98701 gcgtttcact tccatcgtaa aacggttaat aggatattcc aatttttcag gagcataatt
    98761 gaagaaatgt ccaaatcccc cacctagaaa aggtgctgca cctgcttgcc agaatagcca
    98821 attcaaaact tctacctttt ccacaggatt acttggtaaa aaggctccaa atttctcagc
    98881 aaggtaaaga agaatatgag cagactcaaa gactcttacg ttttcagtac ctgactggtc
    98941 caataaggct ggaatcttgg aatttggatt gagcttcaca aagtctgagc cgaattgatc
    99001 cccatccatg atagcaatct tatacaagtc gtaagccgct tccttaaaac cagcttctag
    99061 taattcttcc aataagatag taaccttcac accatttggt gttcccagtg aataaagctg
    99121 aaaagcttgt tctccttttg gcaagttttg ttcgaaacgg gcacctgctg ttggtctgtt
    99181 tagccccgta aaagctcctt gattactagc ttcatcctgc catacggtcg gtaattgata
    99241 tgctgacatc cgaaacctcc cttaaatcgc attcttgtca aaaccgagtt tgcgttgaat
    99301 aaacttaacg atttcgacga tgataatcat tgagaagctt ccagccataa caattcccca
    99361 ttgtgacaag tctagtttgg ttacgtggaa gattccttca agcggttcta caacgattgt
    99421 tgccatgaga aggataaagg ataccaagat ggaccagtta aaggtcttag acttgaatgg
    99481 gccaactgtc aagatggatt ggtagacaga cttgacattg taggcatgga agagctgaat
    99541 caaaccaagg gttgcaaagg ccatcgttag ggcatctgca tgaatagcat gattgtcacc
    99601 cacatgaact gggtaagcaa tcgcaaggcc ataaacactc ataacaagag ctgcttggag
    99661 tacaccttga taaatgatag aactcaaaac accacctgag aagaagcttg ccttgcgtcc
    99721 acgtggttta tgattcatga caccaggttc tgcaggttca acaccaagag cgatagctgg
    99781 gaaggtatcc gttaccaagt tgatccacaa aagatgaacc ggctgtaaga catcccaacc
    99841 aaacaaggtt gataggaaga tggttaatac ttcagcagta ttagcagaaa gtaggtactg
    99901 aatagtcttt tgaatgtttg agaagacctt acgtccttct tccactgcga cgataatagt
    99961 cgcaaagtta tcatctgcaa gaatcatatc agaagccccc ttagaaacct ctgtaccagt
   100021 gattcccata ccgataccga tatcggctgt tttcagagct ggcgcgtcat tgacaccgtc
   100081 acctgtcatg gcaacgactt taccttgttt ttgccaagcc ttgacgatac gaaccttgtg
   100141 ttctggagac acacgggcat aaacagagta ttgaccaacg actttttcaa attcttcatc
   100201 tgacagttca ttgagttcag caccagttaa aacgtgacct tctgtatcgt ttgcgtcaat
   100261 gattcccaaa cgtttggcaa tggcttccgc tgtgtcttgg tggtcacctg taatcataat
   100321 tggacggatt cccgcttcct tagccacacg aacagcctca gcggcttcag gacgttcagg
   100381 gtcaatcatc ccaatcaaac cagtaaaaat taaatcattt tcaagctctt cagaagtgag
   100441 attttctgga atactatcga taatcttata agcacctgca aggacacgca aggcttgatg
   100501 agccatttca gaattgtttg tatgaatgag atttgtaacc ttctcatcaa tcggagcaat
   100561 atccccagcc ttatcacgaa gaagacaacg ttttaagagt tggtctggcg cacccttgac
   100621 tgctacaagg aaacgaccat ctggcaatgg gtgaactgtt gacatgagct tacggtcaga
   100681 gtcaaatggc aattcagcta cacgaggata tttctctaag aaacctttga catcatagcc
   100741 cttgtccaag gcatattgga taaaggctgt ttcggttggg tcaccaatca agttaccttc
   100801 cacatcgatt ttcgtatcat tggccaagac aactgaacga agtagtggca tttcaagacc
   100861 tagttcaata tcatcagctg agtcatgtag aaccgcatcg tagaagactt tttcgactgt
   100921 catcttgttc atagtcagcg taccagtctt atcagaagcg atgatttcag ttgaaccaag
   100981 tgtttcaact gctggcaact tacgaacgat ggaatgtcgt ttggccaaaa cttgagtacc
   101041 aagagaaaga acgatggtaa cgatagcagg aagtccttct ggaatggctg caacggcaag
   101101 ggcaacagaa gtcaacaact caccaagtgg atttttccct tgaatgaaga cacccactac
   101161 aaaagtaaca agggcaatga ccaagatagc ataggtcaag accttagaaa ggttgttcaa
   101221 gttttgtttg agtggtgtat cagtctcatc cgcatcttga agcataccag caatatgacc
   101281 aacttcagtg tacatacctg tattgacaac aacacccatc ccacgaccat aggttacgtt
   101341 tgagttttgg aaggccatgt tgacacggtc accaatacca gcatctgtcg caagctcgac
   101401 tgacaagtct ttttcgactg gtacagattc acctgtcaag gctgcttctt caattttaag
   101461 agagttggct tctatcaaac gtaggtccgc tggtaccacg tcacctgctt caagggcaac
   101521 gatatcgcct ggtaccaatt ctttagagtc aatctctgcc atgtgtccat cacgaagaac
   101581 gcgggcaact ggactagaca tggatttgag ggcttcaata gcttcttcag cttttccttc
   101641 ttggtaaaca ccaaaggcag cgttgatgat aaccacagct aggatgataa tggcatctgc
   101701 gatatcttcc ccaccagaag tcacgactga caagattgct gccgcaacta ggatgataat
   101761 catcaaatcc ttaaattgct cgatgaattt gaccaagatt gatcgtttct cgccttcttc
   101821 gagttcattg tgcccaaatt cggcaaggcg cttttccgcc tcacttgatg acaaaccttg
   101881 ctcggtcgca tccacagcct gcaagacctc ttcagggctc tgagtataaa acgcttggcg
   101941 tttttgttct tttgacatgt gtctcctcct tgacattgtg tgcaaaacag actctctttc
   102001 tgtcatatct tttcacgaca aacaaaaaga gacctgttaa tcataacaag tctcgctgtt
   102061 taagataggg ccggaaagca tacttttcag cataaaattc ggaatgacga cactatcaca
   102121 ggtttctgcc agctactccc ttgagtagta ccattatacc aaattttggg gagttttcaa
   102181 agagtaaaaa ctgccttatt tgaatttttc cttgaaaacc agtataatgg tagaatgcta
   102241 tgtgactaga aaggaagttg aatgaagcaa tctatctcaa atctcaagtt agctgagcgt
   102301 ggagccatta tcagtatttc gacctatttg atcttgtctg cagctaaatt agcagctggt
   102361 catctccttc attcatccag tttggtggcc gatggtttta ataacgtatc ggacatcatt
   102421 ggaaatgtgg ccctcttaat cgggattcgg atggcgcgcc agcctgcaga ccgtgaccac
   102481 cgttttggtc attggaagat tgaagatttg gcaagcttga tcacttctat catcatgttc
   102541 tatgtcggtt tcgatgttct aagagatacc attcaaaaga ttctcagtcg ggaagaaacg
   102601 gtcattgatc ctcttggtgc aactctagga atcatttctg cagcgattat gtttgtggtc
   102661 tatctctaca atactcgcct cagtaagaaa tccaactcca aggcgctgaa ggcagctgct
   102721 aaggacaatc tttctgacgc tgttacctca cttggaaccg ccattgccat cctagctagt
   102781 agtttcaatt atccgattgt ggataaactg gttgctatca tcatcacttt ctttatcttg
   102841 aagactgcct atgatatctt catcgagtct tcctttagtc tttcagatgg ctttgacgac
   102901 cgcctgctcg aggactacca aaaggctatc atggaaattc ccaaaatcag caaggtcaaa
   102961 tcgcaaagag gtcgcaccta cggtagcaac atctacctgg atattacact agagatgaat
   103021 cctgacttgt ctgtttttga aagccatgaa atcgcggatc aggtcgagtc tatgctggag
   103081 gagcgttttg gcgtctttga taccgatgtc catatcgaac cagcacctat ccctgaggat
   103141 gaaattttag acaatgtcta taaaaaattg cttatgcgtg aacaattgat tgaccaagga
   103201 aaccaactag aagaactctt gactgatgat tttgtctata ttcgccaaga tggagagcag
   103261 atggataaag aggcttataa gaccaaaaaa gagttaaatt ctgctataaa ggacattcaa
   103321 attacttcca tcagtcaaaa aaccaaactc atctgctatg agttagatgg tatcatccat
   103381 accagtatct ggcgtcgcca cgaaacctgg caaaatatct ttcatcaaga aaccaaaaaa
   103441 gaatagagaa atcctttcat gagacgggat ttttctattc ttttatactc aataaaaatc
   103501 aaagtgcaaa ttaggaagcc ggtcacaggc tgtacttgag tcggcaatgt gaagccgaca
   103561 tagtttgcac tttgattttc gaatagtctt aactatcaaa ttcactgaga tactcatagc
   103621 gttcgtattt ttcaaggagt gcttcatttt tctcatccaa ttctttttgg agagtagcca
   103681 gcttaccaaa gtcagagccg ttagcctgca tttcctcttc aatagcagcg atacgttttt
   103741 ccaaggtttc aatatcacct tcaatacttg cccactcctg cttttcttgg taggtcatgc
   103801 gtttcttgtc ttctcgaacc ttgaccactt tttccttttc gaccttttgc acttgattgg
   103861 ccatatctgt ttcaaaagct ttttcatcaa gatagtcggt gtaatgacca aagaaaggac
   103921 gaatcttgcc atcctcaaaa gcgagaatct tggtcgctac cttatccaag aaatagcggt
   103981 cgtgactgac tgttaaaacg ggacctgcaa aaccttgcaa gaaattctct aagactgtca
   104041 aagttgcaat atctaggtca ttggttggct cgtctaaaag aagaacattt ggtttttcca
   104101 aaagcagttt gaggagataa agacgttttt tctcaccccc tgacaatttc tcaatcaagg
   104161 ttccatgcgt cgaacgtggg aaaaggaact gctccagcaa ctctgcaatc gaagtcgtag
   104221 aaccgccact ggtcttgacc tcttctgcca cttcctgcag gtaattgata actctcttgc
   104281 tttcatccaa accctcaatt tgctgagaga aataggcgat gcgaacagtt tccccaatca
   104341 caacttgtcc tttagttggc tcaagacttc ctgcaatcaa gttgagcagg gttgattttc
   104401 caacaccatt gtccccaacg attccgatac ggtctttggc ctgcaccaag agattaaaat
   104461 cttgcaaaat aggcttgttt tcataggcaa aggaaacagc ctgaaactcg atgactttct
   104521 tcccaatccg actggtttca aagttcatgg tcaagtctgt ctcagcacta ctgcctgaaa
   104581 cttccttttt cagatcatgg aatcgattga tacgggcctg ctgcttggtc gcacgcgcct
   104641 gcggttgtct gcgcatccag gccaattctt gtttgtagag ttgttctttt ttgtgaagaa
   104701 gagccgcgtc gcgctcatcc tgttccgcct ttaggcgaac atagtcctgg taatttccct
   104761 ggtactcggt caagcctgca cgatccaact cgaaaatccg tgttgacaaa gcgtctaaga
   104821 aataacgatc gtgagtgata aaaaggacgg tcttcttaga atttttcaaa aagagggtca
   104881 gccactcaat aatcgcaata tccagatggt tggtcggctc atccaaaagc aagaggtcgt
   104941 ggttgccaag taagacttgt gccaactgta cccgtcttct cagaccacct gacaattccc
   105001 caacaggagt agataagtct tgaatgccca atttgctaag aacggtcttg acctgacttt
   105061 cgatttccca agcttggaga gagtccatct ctgccatgac acgttccaaa cgcgcctgct
   105121 tgtcctcact atagtcgagc ataatcaatt catactcacg aatgagctgg atttccttga
   105181 gttcactaga tagaaccgta tccaaaactg tctttctatc atcaaaatca ggatcctgag
   105241 tcaagtaacc aatctggtaa tcatttttag ctgaaaaagg actgacatcc ccatcaaatc
   105301 cagaaacacc agaaaggacg tccaaaaggg tggtcttgcc agtcccattg acaccgatta
   105361 aaccaattct gtctaagtca tggataataa aggaaatatc cctaaaaacg gtcttgtcac
   105421 caacggattt acttagtttt tcaacgataa aatcactcat tttttctccc tcaggtaagc
   105481 atggatggct tcacgattat tctccaattc tccatcgaca atggcaaact caatctctgt
   105541 taaaatctct cccaagtctg ggcctggctg atagccatat tccttgatca aaataccgcc
   105601 attaatctga atctctttct tgtcatggat agtcaagctt tggtattttt ctgtgatggc
   105661 ttgtgggttg acttcttttc cttgagcttg acgaagattt tcagcctgta aaagcaaatc
   105721 tatgtcaaag cgataacaat ctcgcttgct caattctcca ttttcacgca gagccaaaat
   105781 aatcagcaaa tcctgaactt gcttggcaaa ctggcgtgag gtcttccaag atttcaaaag
   105841 tgactgcgca ttttcaatct ccaaagccca tagtaaagcc gcccaggctt gttcagagga
   105901 ttcaaaagta aaatcagtct ccaaatcaaa cagtctgttg agcttgtcct ggctagatgc
   105961 catatcaggg agatagtcat aagcttgact ctcaatcatg gaagccaagc cccttctcca
   106021 aaatggagcc agcaagagtt tatcaaactc gacgaaggta cgctctacag aaattttctc
   106081 caaaagcggc gtcaaggtct tcatagcttt aaatgtttct ggctcaagtg caaaaccaag
   106141 actagcctga aaacggaaac cacgcataat ccgtaaagca tcttcgttga aacgctcact
   106201 agccactcca actgctcgca agacttgctt ttccaaatct tctaaaccat ggaacaagtc
   106261 aacgatttct cctgtctcat ccaaggcaaa ggcgttgact gtgaaatcac ggcgtttgag
   106321 gtcttcttct agcgatcgta caaaggaaac cgcactgggt ctgcgatagt ccacatagac
   106381 atcctctgtc cgaaaggttg ttacctcata ctcctcatcc ccatctaaga ccaagacggt
   106441 tccatgctcg attccgatat cggctgttcg cggaaaaatc tgcttggtct cttctggata
   106501 agaagacgtc gcaatatcca catcgtggat agggctatgg agaagggcat ctcgaacaga
   106561 gcccccaaca aaataagcct caaagcctgc ttctttaatt ttttctaata ctggtaaagc
   106621 cttctgaaat tcagaaggca tttgcgttaa tctcataata agtgttctaa tccatagaca
   106681 agctcatgac gcttgacaac ttctttaatt cccaaattga ctcctgtcat gaaggagatg
   106741 cgatcatagg agtcatgacg gagggtcagc ccttctccct gattgccaaa gatgacttcc
   106801 tgatgagcta ccaagcctgg caaacgaact gagtggatgc gcataccatc aaagtcagca
   106861 ccacgagcac cagcaatcag ctcttcctca tctgctgcgc cttgctgaat ggactctcga
   106921 acctctgcca tcaactcagc tgttttaatg gctgttccac tcggagcatc ctttttcttg
   106981 tcatgatgga gctcaataat ctccacattt gggaaatatt tggcagcctg cgtcgcaaat
   107041 tgcatgagta agacagcacc caaggcaaag ttaggggcaa tcaggccacc caagtcttgg
   107101 gcacgagaaa attcttttag ctctgcaatt tcttcactcg tgaaaccagt cgttccaact
   107161 actggagcaa agccattttc aagagcaaaa cgtgtatttt cgtaggcaac agctggagta
   107221 gtaaaatcta cccagacatc cgcttcaaaa ccagctaaat cagccttatc cttgaaaaca
   107281 ggaataccct gccattctga ctcagactca aaaggatcca aaactgccac caagtccaag
   107341 tctggatcag tcaataccat ctgacaagca gcctggccca tctttccctt aaaaccggca
   107401 ataattactc gaatactcat ctctactcct gtctaagata caaagtccgt aagaacacaa
   107461 agtgaaaata ggaattccaa tcaagaagtg tctacttctt ggaagaacta tctttttcac
   107521 acagggttcc aggcgtgttc aattatcaag atacaaagga ccttagctgc ctctgaaaaa
   107581 tagggaatgg cactgacttt ccacgaaagg caagacaggc atcttttttc aagaggcagg
   107641 tagtccgtgt tcaatttcta agatacaagg catcttaact agcctagaag cgccaactaa
   107701 atcactggaa tataacccag agcaatactt cctgctccta ggtgcgttcc aatgacacta
   107761 ccaaatgtag caagtgaaac atccgaaccc aagccaaaat caagcaagtg ctgacgcaat
   107821 tcttcagcct tttcaggagc attcccatga atgacaatga cccggtattg acctgaagcc
   107881 gttgtttcct tgataatttc aattaagcgc ttggtggcct tcttttcagt acgaactttt
   107941 tcgtaaactt caatcacacc ttgatcgtta aaataaagga ttggcttaat gctaagcaaa
   108001 ttgcccaaaa tggcagcccc atttgaaagg cgtccacctt ttaccaaatg atccaagtca
   108061 tctaccatga taaaggctga cgtacggctg atttgaatgg ctagcttatc ctgaatgctg
   108121 gcaaaatcat cgccctgatc acgccaatta aagacgcttt caaccatgat gcctagggga
   108181 gcacttgtaa tcaaagtgtc tgggaaagca atggttaagc cctcatagtc atcgaccata
   108241 tactggatat tttggtaaaa acctgaaatt ccagaagata ggaaaagccc caaggcatgt
   108301 gtatagcctt gttctttgag cgaagttaag atctcatcta acttggcaat acttggttga
   108361 ctggtcttag gcaattcaga agcctgagcc attttttggt aaaattcctc agcagacaga
   108421 ttgatgcctt cgacatattc ctcaccatca atattgacag gaatatccaa gacaaacaag
   108481 tcttctcttt gcaaggtctc ttcactgaga taagcagagg aatctgtgaa aacagctaat
   108541 ttcatattag aactccaaat taattcctgg taagtctaat gcaatttcag tcacttcgta
   108601 agtcaaacga ttgagcatgt tcaaacatgg acgagccaag gtttccacct cttcttggtt
   108661 caattcactt ggttcattga caatacggcc atcgatatgg tttacttgtg agattgttcc
   108721 actaatgaca aacttatcaa atacaatcat aaagctcaag atgacaatca aggaagtcac
   108781 ttgattttct tggtcatgtt ggagcaattg gaaattcaca tccaccttgg tttcaggagc
   108841 tccattttca ttttcccatt caaaattacg tgcatcaaaa tgatactgac taacaaattc
   108901 ttgttcacgt ttaagattca tgtctttctc catcggctac aatattataa gctattgtac
   108961 cataattttt tattttcatc tagttttcta ggatttagtc aatcccaatt tcagcacgaa
   109021 ctacatctgt gatggtatca acatagtagt ccacttcttc tgttgtaggc gcttctgcca
   109081 taacacgcaa gaggggctct gttccacttg gacgaacaag gatacggccg ttccccgcca
   109141 tttcttcttc catcttctcg atgatggcct tgatagctgg cacttccatg gccttttcct
   109201 tcatgacgtt ttccactcgg atattaacta atttttgtgg ataaatcgtt acttctgccg
   109261 ccaactctga taagctctta ccagtttcct tcataatttt agtcaattga actgctgata
   109321 attgaccatc acctgtggta ttgtaatcca tcaagataac gtgaccagac tgttcaccac
   109381 caaggttgta gcctgatttt ctcatttctt caacaacgta gcggtcacca actgcagtaa
   109441 ctgccttgtt aataccttcg cgattcaagg ccttgtggaa accaaggtta gacataacag
   109501 ttgtcacaat tgtattttga gccaattgtc ctttttcaga aaggtatttt ccgatgatgt
   109561 acataatctt gtcaccatcg acgatgtcac cattctcatc aacagcaatc aagcggtcac
   109621 tgtctccatc aaaggccaaa ccaatagctg acccactttc tttgaccact tcttgaaggg
   109681 cttctggatg tgttgaacca acattaaggt tgatgttaag accgtctggt gtttccccga
   109741 taaccgtcaa ttgggcacca aggtctgcaa agatttgacg ggcactggta gaagctgctc
   109801 cattagctgt atccaaggca accttcattc catcaagagg agttccagtt gaaacaaggt
   109861 atccttcata cttacgcaag ccttctggat aatctaccaa aattcctaag ccttctgcac
   109921 ttggacgagg aagagtgtct tcctcagcat ctagcaaggc ttcaatttct gcttcttttt
   109981 catcatctag tttgaagcca tcaccgccaa agaacttgat tccgttatca agggctgggt
   110041 tgtggctagc agaaatcatg acaccggcac ttgctccttc agtttcaacc aagtaagcta
   110101 ctgctggtgt tgcaaggaca ccaagtttgt atacgtgaat ccctactgaa aggagacctg
   110161 ccaccaaggc cgattccagc atttcccctg aaatacgtgt gtcacgtcct acaaagactt
   110221 tcggcgcttc cgtttcatgt tgactaagaa catagcctcc aaaacgtcct agtttaaagg
   110281 ctaattctgg tgttagttct aggttagctt ctccacggac tccatcagtc ccaaaatatt
   110341 tacccattgt tataaaatcc ttttctattt ttaattcgtt tttgaactag ttgctttcgt
   110401 tgacgaagat gtctccgatg aactgcttgt acttgaattt gatgtgcttg aacttggtgc
   110461 tactggtttt gtagtcacct tcattattgt atcaaacgga gtgataactg ccggtaagac
   110521 aacaccattg cgatcgattg cctgcaaagg tactgaacca ctgtaattac ctgttatgcg
   110581 ttcgctagtt ggcaagacag cgataatctt atcaattcta tccaatgtct cttggtcact
   110641 cgtaatagac acttctttat ctgacaccat gacattttca atttgtaccc gactatcaat
   110701 ttgactaggg tcaatctctg gtacaatctt taccttatcc ttctgagcct tcttaccaat
   110761 cttgactgta attttttgcg gagtcgccac agcggtcagc ccattgggta aatcttcaat
   110821 gctcaaagga acttcaatcg ttccaacacc ggcatctgtt aggtcagcag taaccttgaa
   110881 tttacgtgta ctttcttgca tttcactagc tagcgatagg cgatttgcac cagtcaagac
   110941 cactgatact tctgaagcaa aaccgctaat aaaatactta tcactattat agcgtatgtc
   111001 aatagggaca tttgttactg tattagtata ggtttccgtt tttacctgcc tagcactggt
   111061 actgttttga aaattcgtcg ccgtagcata gacaaataag acacaagcaa aaaagagtga
   111121 ggatatgata tataaactat tttttttcat gtttccatcc tcctagcaat cgttctttaa
   111181 aactaagacc cacttcctct tttggaagta agatttcacg taattctgtt tcaaattcat
   111241 caagtgttag gttgtgctta aaccttccat tataggttat cgaaattcct cccgtttcct
   111301 ctgatacgac aaaagtcaag gcatctgaga cttctgataa accgatagcc gcccggtgtc
   111361 tggtcccaaa ttccttggaa atccctgtgt tttttgtcaa gggcagatag gcagacgtca
   111421 cagcgatacg ttcttctttg ataatcaccg caccatcatg taggggagtg ttgggaataa
   111481 aaatgttaat gagaagttct gcagaaatct tagcatccaa gggaattcct gtcgaaatat
   111541 actcctgcaa ggtacgtaca cgctgaatag caaccaaggc cccgatttta cgaggactca
   111601 tgtattcaac agacttaaca aaggcacgaa tcatctgttc ctcagcacta ataggggcat
   111661 tggaaaagaa atctgtcgct cttcccaaac gttccaaacc agtccgaatc tctggagaga
   111721 agataacaac cgccgcaata accccataag taataatttg attgattaac caagaaatcg
   111781 tagtcaaacc aatcatattt gcaaggattt gagctaaaat aaacaccaaa actccacgta
   111841 ccaaaatcat aatcttggtt cctgcaatag cttttgtaaa atggtataaa atataagcaa
   111901 caatcaaaat atcaatcaga ttgatagcta tcgtccatgg acttgcaaac aaactggtcc
   111961 aatattgcag attggataat tgttgaaaat tcatccctga tatcctccct atcaaaacac
   112021 tttcgtccta ttataccatt ttctggcatt tttttcccta tcctagtcca ttttacattg
   112081 aacaaaaata tgataaaata aactgactag aaaaaacaaa ggagaaacta tgtctcaact
   112141 ctatgatatt accattgtgg gtggtggtcc tgtcgggctt tttgcagcct tttatgccca
   112201 cctacgccaa gccaaggttc aaatcatcga ctctcttccc cagctaggtg gacaacctgc
   112261 tattctctac cctgaaaagg aaatcctaga cgtaccaggc ttcccaaacc tgactggaga
   112321 agagttgact aaccgcttga ttgaacagct aaatggattt gataccccta ttcatctcaa
   112381 tgaaacggtt cttgagattg acaaacaaga agaagaattt gccatcacaa cttctaaagg
   112441 aagtcacctg actaaaacag tcattatcgc tatgggtggc ggtgccttca aaccacgtcc
   112501 gctggaactt gaaggtgttg agggctatga aaatatccac taccacgttt ctaacattca
   112561 gcaatacgct ggtaagaaag tgacgattct tggtggggga gactcggctg tggattgggc
   112621 tttggctttt gaaaaaatcg caccaactac ccttgttcac cgcagagata atttccgtgc
   112681 cttggaacac agtgttcaag ccttgcaaga atcatctgta accatcaaga caccattcgc
   112741 ccctagccaa ctccttggaa atggaaaaac acttgataaa cttgaaatca caaaagtcaa
   112801 atctgatgaa actgaaacca ttgacctaga ccacctcttt gtcaactatg gtttcaaatc
   112861 ttctgtcggt aaccttaaaa actgggggct caacctcaac cgtcacaaga ttatcgtcaa
   112921 cagcaaacag gaatccagcc aagcaggtat ctatgctatc ggtgactgct gctactatga
   112981 cggaaaaatt gatctgattg cgacaggcct cggagaagct ccaactgctg tcaacaacgc
   113041 tatcaactac attgaccctg aacaaaaagt acaaccaaaa cactctacca gtttataaaa
   113101 aagaaccact agtcacatag gattcgtggc tttataattc atccgcattt aaaaatacct
   113161 ttacatcgtt ttactatatc ttacaatacc ttttaaaaca gctatatttt gagcttttaa
   113221 ataaatgttt ttacatcatt ttacagagat ttacgacact tttgcccctt ttttgcccct
   113281 tttgagcaaa caaaaaaacc gcaagcctga gcctgcggtg aaagaacaat ttagaaagtt
   113341 tcctttctat ttatttaact gtaatcaagc catctggctc tactgtgaac tctggcttgt
   113401 ctgccagtgt tccgtctggt ttgaggtagt accagcctgt tccgtccgct gactggataa
   113461 aggcatttga taccatggcg ccttctttag cgtctaagta gtaccaagtg tccttgtact
   113521 tgacccagcc tgtcttcatg gcaccttcta catcaaaata gtaccacttg tcagcgattt
   113581 tctgccagcc tgtggccatt tcgcctgatt ggtcaaagta gtaccaatta ccgtctgtgt
   113641 gcttcttcca gcggtctgaa agcatatagc ctgagccatc gaaataatac caggtaccgt
   113701 tgattttctc aaacttatct tttggataag agccgtctga gtgtacgtac cagtagccag
   113761 tgccattttt ctgccagcct gttgcagctc tcaagccgtt ttcgatgtct tgcttaaact
   113821 gttcacggct aatgccccat ttagcaagat atggatatgg atccacatgg tctgagtggt
   113881 tgtttggttg gttattggta cagtattcat gcgtcttgat acctgccaag tcgtctgtat
   113941 caagagtctt cggcaagcct gcttcgtccg ctagattgcg tagcaattcg atatagaggc
   114001 gatagtcagc cataaactct tccttagttg aatggctttc aatcagttca accgctgcat
   114061 aggtctcagc attccaaccg cccccaacat cccaacttcc gttgttcaca ggtcctacct
   114121 gcaggacacg accgttccca acaacgtgcg agaaaaaacc taattctggg tctttccgcc
   114181 agtgataatc cgcttcattc tgtacggttg agttgcggtt acctgttgag tgagcatgta
   114241 cttgtcgata aggctgcacc ccaacctgtg gcaagcctgt acgtagtctg tttctatcga
   114301 tatccattcc ctatcgtcct ttccatgcgt cattcatctg cttcactgct gactctacga
   114361 aggtgtctaa gtctttgtca gtcatgctaa tattgtattt tgtaagctca gcacggactt
   114421 tagcacgagc ctgtgccagc ttttcatcgc ctttaaagcc agtctctgag gcaacctgct
   114481 caacggcatt tactgcgtt
//
LOCUS       DAVLMQ010000002       101608 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000002 DAVLMQ010000000
VERSION     DAVLMQ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 101608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 101608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..101608
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.002"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            484..936
                     /locus_tag="VXF95_000117"
     CDS             484..936
                     /locus_tag="VXF95_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1080731.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFTYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            955..2292
                     /locus_tag="VXF95_000118"
     CDS             955..2292
                     /locus_tag="VXF95_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HEV1080732.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFMQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIRGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            2371..3255
                     /locus_tag="VXF95_000119"
     CDS             2371..3255
                     /locus_tag="VXF95_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1080733.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            3255..4088
                     /locus_tag="VXF95_000120"
     CDS             3255..4088
                     /locus_tag="VXF95_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1080734.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAIFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            4106..6199
                     /gene="nanB"
                     /locus_tag="VXF95_000121"
     CDS             4106..6199
                     /gene="nanB"
                     /locus_tag="VXF95_000121"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HEV1080735.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADKPNSLQALFGLSNSKAGFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSNIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     DETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLREKHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFENATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSEVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            6212..7315
                     /locus_tag="VXF95_000122"
     CDS             6212..7315
                     /locus_tag="VXF95_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1080736.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
     gene            7489..8187
                     /locus_tag="VXF95_000123"
     CDS             7489..8187
                     /locus_tag="VXF95_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1080737.1"
                     /translation="MPQISKEALIEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAA
                     EQGGAVGIRANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIE
                     VIALDCTKRERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTL
                     SGYTSYSPKVDGPDFELIKKLCDAGVDVIAEGKIHTPEQAKQILEYGVRGIVVGGAIT
                     RPKEITERFVASLK"
     gene            8206..9723
                     /locus_tag="VXF95_000124"
     CDS             8206..9723
                     /locus_tag="VXF95_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1080738.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            9848..11176
                     /locus_tag="VXF95_000125"
     CDS             9848..11176
                     /locus_tag="VXF95_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1080739.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            11428..12294
                     /locus_tag="VXF95_000126"
     CDS             11428..12294
                     /locus_tag="VXF95_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1080740.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            12310..13149
                     /locus_tag="VXF95_000127"
     CDS             12310..13149
                     /locus_tag="VXF95_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1080741.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            13421..13873
                     /locus_tag="VXF95_000128"
     CDS             13421..13873
                     /locus_tag="VXF95_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1080742.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYDIDGD
                     KVFLVVQENVLNQAENDQFEYHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEASDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPNGYAGMEEKVRKYLFKILID"
     gene            14006..14314
                     /locus_tag="VXF95_000129"
     CDS             14006..14314
                     /locus_tag="VXF95_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080743.1"
                     /translation="MDGQGITVDEMAWIIRGIVNGLIGRYIKLGTYAAKYGISMARSI
                     LSRAAATAAARVGLSTKISGWILRVAVNVADVYGNFANNIAAAWDAHDKIPNNGRINF
                     "
     gene            14324..14623
                     /locus_tag="VXF95_000130"
     CDS             14324..14623
                     /locus_tag="VXF95_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080744.1"
                     /translation="MKALCIFLLNMLAWTVLAMIIRGGLDGFDEHTWSTILIASLFGV
                     YDYKPIDKNRKKSKRKKKKEKIDLFMVGTYESFTDKKENSLQRKMMEEQTWHKKE"
     gene            14605..15249
                     /locus_tag="VXF95_000131"
     CDS             14605..15249
                     /locus_tag="VXF95_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1080745.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLMELGIVFLTLSDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLSWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            15418..16335
                     /locus_tag="VXF95_000132"
     CDS             15418..16335
                     /locus_tag="VXF95_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HEV1080746.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            16353..17237
                     /locus_tag="VXF95_000133"
     CDS             16353..17237
                     /locus_tag="VXF95_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1080747.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(17253..18104)
                     /locus_tag="VXF95_000134"
     CDS             complement(17253..18104)
                     /locus_tag="VXF95_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1080748.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLLDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            18304..20361
                     /gene="pbp2b"
                     /locus_tag="VXF95_000135"
     CDS             18304..20361
                     /gene="pbp2b"
                     /locus_tag="VXF95_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HEV1080749.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMAIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQPIVFQGSAPINSWYTQAYGSFPITAVEALEYSSN
                     AYMVQTALGIMGQTYQPNMFVLTNNLESAMGKLRSTFAEYGLGASTGIDLPDESTGFI
                     PKEYNFANYITNAFGQFDNYTPMQLAQYVGTIANNGVRIAPHIVEGIYGNNEQGGLGN
                     LIQSVESKEMNKINISESDVSILQQGFYQVSHGGSALTTGRAFSNGASVSISGKTGTA
                     ESYVEGGQEANNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYNQHH
                     PMN"
     gene            20372..20968
                     /gene="recR"
                     /locus_tag="VXF95_000136"
     CDS             20372..20968
                     /gene="recR"
                     /locus_tag="VXF95_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HEV1080750.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSDDDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            21144..22187
                     /locus_tag="VXF95_000137"
     CDS             21144..22187
                     /locus_tag="VXF95_000137"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HEV1080751.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVDYDRFTVKTFFISQ
                     SGDFIKTQEFSHDPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFTKPSNMGSSVGISKSENQEELRQALELAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            22271..23644
                     /locus_tag="VXF95_000138"
     CDS             22271..23644
                     /locus_tag="VXF95_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HEV1080752.1"
                     /translation="MKLTIHEIAQVVGAKNDISIFEDTQLEKAEFDSRLIGTGDLFVP
                     LKGARDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLAP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQVLDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQMILSLSPDVLDTVIFYGENIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGVHDQILLKGSNSMNLAKLVE
                     SLENETK"
     gene            23631..24242
                     /locus_tag="VXF95_000139"
     CDS             23631..24242
                     /locus_tag="VXF95_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1080753.1"
                     /translation="MKPSDFVKYLQRMIALTDTGLTFTKDPFDRERYEDLRSLLSEML
                     NQVSDLDAEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYAKFVFECKLLDGQFQEN
                     QEIAALQFFAIDQLPNLSEKRITKEQIEILWQVYQGQREQYLD"
     gene            24333..25037
                     /locus_tag="VXF95_000140"
     CDS             24333..25037
                     /locus_tag="VXF95_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HEV1080754.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            25256..26629
                     /gene="ftsA"
                     /locus_tag="VXF95_000141"
     CDS             25256..26629
                     /gene="ftsA"
                     /locus_tag="VXF95_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HEV1080755.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVESVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            26646..27905
                     /gene="ftsZ"
                     /locus_tag="VXF95_000142"
     CDS             26646..27905
                     /gene="ftsZ"
                     /locus_tag="VXF95_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HEV1080756.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVSPQARTATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            27910..28581
                     /locus_tag="VXF95_000143"
     CDS             27910..28581
                     /locus_tag="VXF95_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HEV1080757.1"
                     /translation="MNVKENTELVFREVAEASLSAHRESGSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDIIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKAAQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            28591..29130
                     /locus_tag="VXF95_000144"
     CDS             28591..29130
                     /locus_tag="VXF95_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HEV1080758.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSAGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            29130..29393
                     /locus_tag="VXF95_000145"
     CDS             29130..29393
                     /locus_tag="VXF95_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HEV1080759.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            29390..30175
                     /locus_tag="VXF95_000146"
     CDS             29390..30175
                     /locus_tag="VXF95_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HEV1080760.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEYL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELDLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLLQDKGQTKKEKKKITVQLLLSK"
     gene            30184..30972
                     /gene="divIVA"
                     /locus_tag="VXF95_000147"
     CDS             30184..30972
                     /gene="divIVA"
                     /locus_tag="VXF95_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HEV1080761.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPVPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVEAPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            31320..34112
                     /locus_tag="VXF95_000148"
     CDS             31320..34112
                     /locus_tag="VXF95_000148"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HEV1080762.1"
                     /translation="MKLKDTLNLGKTEFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     QGKPHFTLHDGPPYANGNIHVGHAMNKISKDIIVRSKSMSGFYAPFIPGWDTHGLPIE
                     QVLSKQGVKRKEMDLVEYLKLCREYALSQVDKQREDFKRLGVSGDWENPYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GVLDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPAGEARKFVVAAELLTSLSEK
                     FGWADVQVLETYRGQELNHIVTEHPWDTAVEELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANNLEVAVTVDERGIMMKNAGPEFEGQFYEKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDEIEKVKFHSEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMVAETIEHVAQLFEEHGSSIWWERDAKDLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVVVNRPELTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFALDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDTVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFETEDFVQLSELPEVQTFANQEEILD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SELTIAEGPAPEAALSFEDVAFTVERAAGEVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            34521..34901
                     /locus_tag="VXF95_000149"
     CDS             34521..34901
                     /locus_tag="VXF95_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080763.1"
                     /translation="MKSKRLALISGIVGLVGGILLLICPFVLLGTAVNTAATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDKHVGAAPSVLMIVSGEVSLIPFLGW
                     VGGILAIIGGSLFLATLKKFKSEE"
     gene            35197..35385
                     /locus_tag="VXF95_000150"
     CDS             35197..35385
                     /locus_tag="VXF95_000150"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080764.1"
                     /translation="MENNDSFTKLKESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQ
                     TVLSFLVLTSFFVKNCVK"
     gene            35436..36128
                     /locus_tag="VXF95_000151"
     CDS             35436..36128
                     /locus_tag="VXF95_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HEV1080765.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            36181..38592
                     /locus_tag="VXF95_000152"
     CDS             36181..38592
                     /locus_tag="VXF95_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1080766.1"
                     /translation="MIRNKKQDYVLAYKQPASTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALATTSYVYKGTRFE
                     RKAFASFPDDLLVQCFTKEGLETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEADVDASTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYETYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TDVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGNGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            38803..39504
                     /locus_tag="VXF95_000153"
     CDS             38803..39504
                     /locus_tag="VXF95_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1080767.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIQMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            39506..42214
                     /locus_tag="VXF95_000154"
     CDS             39506..42214
                     /locus_tag="VXF95_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1080768.1"
                     /translation="MIKRKTYWKDLIQSFTGSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDKEIALATHLQGQYSVGQEISFKEKEEDHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQVQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAS
                     IVTFTTMTRFVDEERTHAGIFKALGYRSKDIITKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHAEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATDQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGKAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNVSAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPSTI
                     LFYPQVGWEVYVIPVVAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(42310..42801)
                     /gene="tpx"
                     /locus_tag="VXF95_000155"
     CDS             complement(42310..42801)
                     /gene="tpx"
                     /locus_tag="VXF95_000155"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HEV1080769.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGHDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(42924..43853)
                     /gene="psaA"
                     /locus_tag="VXF95_000156"
     CDS             complement(42924..43853)
                     /gene="psaA"
                     /locus_tag="VXF95_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HEV1080770.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(43885..44733)
                     /locus_tag="VXF95_000157"
     CDS             complement(43885..44733)
                     /locus_tag="VXF95_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1080771.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(44730..45452)
                     /locus_tag="VXF95_000158"
     CDS             complement(44730..45452)
                     /locus_tag="VXF95_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1080772.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            45743..47635
                     /gene="pepO"
                     /locus_tag="VXF95_000159"
     CDS             45743..47635
                     /gene="pepO"
                     /locus_tag="VXF95_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HEV1080773.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(47758..48387)
                     /locus_tag="VXF95_000160"
     CDS             complement(47758..48387)
                     /locus_tag="VXF95_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1080774.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            49403..51625
                     /locus_tag="VXF95_000161"
     CDS             49403..51625
                     /locus_tag="VXF95_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HEV1080775.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRVIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSGPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            51655..52098
                     /locus_tag="VXF95_000162"
     CDS             51655..52098
                     /locus_tag="VXF95_000162"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HEV1080776.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGLLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(52365..52551)
                     /locus_tag="VXF95_000163"
                     /pseudo
     CDS             complement(52365..52551)
                     /locus_tag="VXF95_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(52715..53365)
                     /locus_tag="VXF95_000164"
     CDS             complement(52715..53365)
                     /locus_tag="VXF95_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HEV1080777.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            53477..54319
                     /locus_tag="VXF95_000165"
     CDS             53477..54319
                     /locus_tag="VXF95_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1080778.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADAQQLGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEEFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            54395..54832
                     /locus_tag="VXF95_000166"
     CDS             54395..54832
                     /locus_tag="VXF95_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HEV1080779.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            54901..55203
                     /locus_tag="VXF95_000167"
     CDS             54901..55203
                     /locus_tag="VXF95_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080780.1"
                     /translation="MYLVIEIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(55294..56367)
                     /locus_tag="VXF95_000168"
     CDS             complement(55294..56367)
                     /locus_tag="VXF95_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HEV1080781.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPREPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSRQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILDAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYHAWKNR"
     gene            56523..57200
                     /locus_tag="VXF95_000169"
     CDS             56523..57200
                     /locus_tag="VXF95_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1080782.1"
                     /translation="MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            57193..58167
                     /locus_tag="VXF95_000170"
     CDS             57193..58167
                     /locus_tag="VXF95_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1080783.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALFFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(58216..60159)
                     /gene="thrS"
                     /locus_tag="VXF95_000171"
     CDS             complement(58216..60159)
                     /gene="thrS"
                     /locus_tag="VXF95_000171"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HEV1080784.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFMISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVDYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(60217..60540)
                     /locus_tag="VXF95_000172"
     CDS             complement(60217..60540)
                     /locus_tag="VXF95_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HEV1080785.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDFKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            61399..62027
                     /locus_tag="VXF95_000173"
                     /pseudo
     CDS             61399..62027
                     /locus_tag="VXF95_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
     gene            62168..62437
                     /gene="rpsO"
                     /locus_tag="VXF95_000174"
     CDS             62168..62437
                     /gene="rpsO"
                     /locus_tag="VXF95_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HEV1080786.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            63252..63866
                     /locus_tag="VXF95_000175"
     CDS             63252..63866
                     /locus_tag="VXF95_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HEV1080787.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(64159..64908)
                     /locus_tag="VXF95_000176"
     CDS             complement(64159..64908)
                     /locus_tag="VXF95_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HEV1080788.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            65041..67377
                     /locus_tag="VXF95_000177"
     CDS             65041..67377
                     /locus_tag="VXF95_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HEV1080789.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            67906..68715
                     /locus_tag="VXF95_000178"
                     /pseudo
     CDS             67906..68715
                     /locus_tag="VXF95_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
     gene            complement(68754..70181)
                     /locus_tag="VXF95_000179"
     CDS             complement(68754..70181)
                     /locus_tag="VXF95_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1080790.1"
                     /translation="MKTTNKVAIYVRVSTTSQVEEGYSIDEQKDKLEAYCKIKDWKIY
                     DVYVDGGFSGANTQRPELERLISDVKRKKVDIVLVYKLDRLSRSQKDTLFLIEDVFAK
                     NDVAFISLQENFDTSTPFGKASIGMLSVFAQLEREQIKERMMLGKEGRAKNGKSMSWT
                     TIAFGYDYSKETGVLSVNPTQALIVNRIFTEYLNGKPVVKIIRDLNAEGHVGRKRPWG
                     ETITKYLLKNETYLGKVKYKDKVYEGQHEPIITQELFDLVQLEVERRQISAYEKYNNP
                     RPFRAKYMLSGLMKCGYCGASLGLRYTRKDKNGISHHKYQCRNRHSKDLEKRCESGWY
                     SKEELERGVIKELERIKFDPKYKNETLAKKEETIKVEEIKKQLERINNQVSKLTELYL
                     DEIITRKELDEKNDKIKTERQFLEEQLENQKSNVLSIRKRKLTRLLKDFDVEKLSYED
                     ASKIVKNIIKEIIVTKDGMSITLDF"
     gene            complement(70349..70549)
                     /locus_tag="VXF95_000180"
     CDS             complement(70349..70549)
                     /locus_tag="VXF95_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080791.1"
                     /translation="MSNESRPMEVIKHNLDCKCHRRREWIRVNDKWHAIEFSVDDPNE
                     PPMTEEEKANVALILQQHLSKE"
     gene            complement(70551..71342)
                     /locus_tag="VXF95_000181"
     CDS             complement(70551..71342)
                     /locus_tag="VXF95_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HEV1080792.1"
                     /translation="MARGRGKLTPQDKEDMKVFSANLNSILSDRNCKQAELSRATGIP
                     PSTLTGYVKGTSLPIPGNVQKIADFFGVPKSVLDPRFITNNFMVNDSSSNTPQIQTIY
                     DELEPPRQGKVLNYAKRQLKEQKNEEETKINEVSEAIRLYSYDYYDHPASAGTGQYLN
                     DVRVERIELPVDVDADFVIPIKGDSMEPDYHDGDLVFIQTSVDLNDGVIGVFNYNGDA
                     YIKQLVIDEDQAYLHSLNPEYKDMPITPDTDFRIIGEVVDLYREK"
     gene            71515..71790
                     /locus_tag="VXF95_000182"
     CDS             71515..71790
                     /locus_tag="VXF95_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080793.1"
                     /translation="MNTLNEKAINIFKAVAKETLIQGTYEENFLYSQLEAFCTNCRQF
                     AFGWTELAEEIERQERYLLDSGFTQEEIDDIRFDAAFAGMLDKLNVA"
     gene            71867..72004
                     /locus_tag="VXF95_000183"
     CDS             71867..72004
                     /locus_tag="VXF95_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080794.1"
                     /translation="MNELERTALNEILRTVTYIAEKVDEIDSKISQSEEDVKINASSA
                     S"
     gene            complement(71959..72645)
                     /locus_tag="VXF95_000184"
     CDS             complement(71959..72645)
                     /locus_tag="VXF95_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HEV1080795.1"
                     /translation="MKTTIVSFSGASRQTVKFEYPEYCPHCGKNISPEMIYVSDSEDS
                     YSSGDARFVVTFRCSRSTCKKYFAVEYIFTSTSKPCIIAEYSYRPPIKVKLPENIEKV
                     SPVFVEIYSQATIAEREALDQIAGVGYRKAAEFLIKDYAISKNPSDEGKIKSIMLGQV
                     ISTYLNDFPKIQVLAKSVAWIGNDETHYVRRHDGKDIDDLKKFILSATQFIAADYDAD
                     EALIFTSSSD"
     gene            72847..73017
                     /locus_tag="VXF95_000185"
     CDS             72847..73017
                     /locus_tag="VXF95_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080796.1"
                     /translation="MKEKLNEFLKFRSQFTKREWIEINQVVEARLNEKADQLKLDDSD
                     VEIISKRLGRSI"
     gene            complement(73242..73448)
                     /locus_tag="VXF95_000186"
     CDS             complement(73242..73448)
                     /locus_tag="VXF95_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080797.1"
                     /translation="MTDYQLEASLIVLGKEFDRTKKNGKESFSVHVSFFDGLDANQHL
                     QEFARQYPVKIDRSNSDQITFLIK"
     gene            73521..73748
                     /locus_tag="VXF95_000187"
     CDS             73521..73748
                     /locus_tag="VXF95_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1080798.1"
                     /translation="MPKMTLRAIRTNYNLSAKEVADKLNIHQQTLLKYEHDSSKIPMD
                     LLDKLARLYNVEKDFIFLGKKYELNHNLGEV"
     gene            73791..74153
                     /locus_tag="VXF95_000188"
     CDS             73791..74153
                     /locus_tag="VXF95_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080799.1"
                     /translation="MQYIIRNTHGNYTSLNNAYAQDKRLKATTIGILTVILMNKSDWV
                     VYPDEIARRLGISRRTVDEHFKLLEKAGYLRVYRLGLGRGKGVTVYRFFSDMPISDDY
                     FEYLKTNLEKELSTDNGV"
     gene            complement(74563..74754)
                     /locus_tag="VXF95_000189"
     CDS             complement(74563..74754)
                     /locus_tag="VXF95_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000834563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080800.1"
                     /translation="MKSFKDFRESLTAEDMQAISAKANEATKQIDHTDGLQLGKVSGL
                     TSVITTIELLEKYHEWLHS"
     gene            74873..75016
                     /locus_tag="VXF95_000190"
     CDS             74873..75016
                     /locus_tag="VXF95_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080801.1"
                     /translation="MEDKIIELADYFISESTTYREAKIACEKLLKQVSHEIELRAMES
                     KTV"
     gene            75083..75880
                     /locus_tag="VXF95_000191"
     CDS             75083..75880
                     /locus_tag="VXF95_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001056933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HEV1080802.1"
                     /translation="MNMNLNTNEILTTTEYDMFRKISNRKITENPKLEEELLSEGQRQ
                     PILVNEKMEVIDGQHRLYYLRKHRKPVRYIIDPTANFKTVISMNTSAVNWALQDYVYS
                     FALEGDPEFVKLAKFLDENELLSDKMVIVAGSGRRDGTAAHVVKKLKKGDYVFSNEKQ
                     LREFCKFYERVLNETKLPNKPFLQSVLWTLYTTSVFDENRMLTQLKKSDLTSEDIEGF
                     AKKKLLLTFLELYNGRWSDDHPSLIQYFINRKGSLTIPSLPKQDEDN"
     gene            75898..76035
                     /locus_tag="VXF95_000192"
     CDS             75898..76035
                     /locus_tag="VXF95_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080803.1"
                     /translation="MKVTVYVYGRKLEPDEPIIIPENHRFYDIWNGIVNEMLDNEEDV
                     A"
     gene            76035..76238
                     /locus_tag="VXF95_000193"
     CDS             76035..76238
                     /locus_tag="VXF95_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080804.1"
                     /translation="MKLLTKLKLRLEGVLKSVNLDWREVAVELMNDLFEERKRRFAFE
                     QENYDLKQQLAIYKEKEQGEQYV"
     gene            76231..76485
                     /locus_tag="VXF95_000194"
     CDS             76231..76485
                     /locus_tag="VXF95_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080805.1"
                     /translation="MFKALKTIKKIKQLQKEMHDASVAFLLMQDLGLVPDSEKGRTIA
                     KSFYDVSHMLKDVLGGKSVDEAMKRLNSEVKIEDVEQEDD"
     gene            76790..76975
                     /locus_tag="VXF95_000195"
     CDS             76790..76975
                     /locus_tag="VXF95_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080806.1"
                     /translation="MKKRLYYKKWKQELREAMREEIDGDYLTEKMVRKMSISDMSHYL
                     NQLALEEAGYCGTMFNY"
     gene            76993..77745
                     /gene="bet"
                     /locus_tag="VXF95_000196"
     CDS             76993..77745
                     /gene="bet"
                     /locus_tag="VXF95_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HEV1080807.1"
                     /translation="MTNNQLATQTKRNITTDPSLLTGADIKKYFDPQNLLTEKQVGQA
                     LALCKGRNLNPFANEVYIVAYTNRNGGKEFSLIVSKEAFLKRAAQCKDYEGFEAGVVV
                     VDSEGVMHERKGAIMLPEDTLIGGWARVHRKNFKVPVEIVVSREEYDKKQSTWNTMPA
                     TMIRKVALVNALREAFPEDLGNMYTEDDGGETFDRIKDVTPQESREDVVARKMAEIEQ
                     FNKEQEANHADPEPAQTEETIQGELLDGELEY"
     gene            77755..78744
                     /locus_tag="VXF95_000197"
     CDS             77755..78744
                     /locus_tag="VXF95_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV1080808.1"
                     /translation="MQELQVIDDKKINKIYEMITTDELTRESFEKDLIEATEKYKDYI
                     PTAGTLKDDKAKRAEFNKLIESKNRIRIDTKNLLSETANTWDSYAKSIIDPFATVVSE
                     FDKGIKEIEEHQRQLKIDTVKSYLANKSAEYMLDPRLFDEKALEYVKASDFMADGVTL
                     KKATMKSLDDMVTFEFQKQQEFEKAKSAISGLCAEYGMTDSPYIRQLKDLTLAEVFQQ
                     IKADYEFEKEELRQAPKSTETPNFDPETGKILDGGQILQNEPNALRGAENDLKRYAQK
                     MTLEVYFVDTAEKDRFKAGLSQLGFDFKKNYQVSGYQRIEPLTQAELNEQCGW"
     gene            78747..78932
                     /locus_tag="VXF95_000198"
     CDS             78747..78932
                     /locus_tag="VXF95_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018165947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080809.1"
                     /translation="MTEIEKISEELAEYGVPDELIGKIEDLLATLYGEKRKLEIEKSW
                     IFLQSQWGGNHGHQKNI"
     gene            78910..79233
                     /locus_tag="VXF95_000199"
     CDS             78910..79233
                     /locus_tag="VXF95_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080810.1"
                     /translation="MDIRKISDSVAIYSDGKKLQVIHNLGDEFILDFKVGEDSVWNLN
                     GQVVEIIDMIEPVFKVFSFCSKSGEGMQRLKHAIVHFEKFEQYIRDNQEDLMIWWHNP
                     GGEYD"
     gene            79226..79561
                     /locus_tag="VXF95_000200"
     CDS             79226..79561
                     /locus_tag="VXF95_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sporulation protein Cse60"
                     /protein_id="HEV1080811.1"
                     /translation="MIKTVFFSCDYPHHEVIDDQINSWLAENPGIKLIDIKFQSNVSA
                     VADSGVSAEYWHTSALIIYKVPSENNISSINSNGLGFIISCEKCGSLSIIKGKDVGQN
                     VCYECKGEK"
     gene            79656..80072
                     /gene="ssb"
                     /locus_tag="VXF95_000201"
     CDS             79656..80072
                     /gene="ssb"
                     /locus_tag="VXF95_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1080812.1"
                     /translation="MINNVTLVGRLVAPPDLRKTPNNVSSLQGTLAVNRNFKNENGER
                     EADFINFQAWRGTADIIAQYCSKGSLIGLTGRLQVRSYEKDGQRRYVTEVIAESVALL
                     ESRNSQHGQGNSFQNGNSSPFTDPNPFDLPNDGLPF"
     gene            80082..80588
                     /locus_tag="VXF95_000202"
     CDS             80082..80588
                     /locus_tag="VXF95_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1080813.1"
                     /translation="MSKIKILDACCGSRMFWFDKNESHTIFMDIRQETFEIHDKKVNV
                     DPDIIGDFRDMPFEDNTFNLVVFDPPHLKWAGPNSIMKAQYGQLDKVTWSEDLAKGFE
                     ECLRVLKVGGTLVFKWSDRQINVKKLLEVIPFKPLFGQQRGTTHWLTFVKFEEDKNGV
                     DGLGGLET"
     gene            80554..80763
                     /locus_tag="VXF95_000203"
     CDS             80554..80763
                     /locus_tag="VXF95_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080814.1"
                     /translation="MEWTDWVDWKPETKTDIKTKIENDGYTFPHYDKKNNGVKYVIST
                     LDIKRDCLRLGVPFEDVYPLQTTLF"
     gene            80777..81106
                     /locus_tag="VXF95_000204"
     CDS             80777..81106
                     /locus_tag="VXF95_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080815.1"
                     /translation="MASKINATERIAIIIEKQKIEVVTTLNYDMSISFDNKDTAPTLD
                     DNGDLFEPVYKCKVKAIPKNDVFFTSLTRVKSNIKTLQEVKKFFEFVNENRENLFEMA
                     GFKGALE"
     gene            81103..81534
                     /locus_tag="VXF95_000205"
     CDS             81103..81534
                     /locus_tag="VXF95_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HEV1080816.1"
                     /translation="MKLTLNIEPKPQSRPRFARRGSFTTTYEDKDMKTWRNHCQLLIA
                     NQYMGQPILEGALRARLRFYIKPPQYISKVKKNQQALLDEIIPVGKKPDIDNYEKALY
                     DSMSGIVFQDDGQIALHDVGKFYSLNPRIEVEIEVMKSLSI"
     gene            81550..81732
                     /locus_tag="VXF95_000206"
     CDS             81550..81732
                     /locus_tag="VXF95_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080817.1"
                     /translation="MADYALYQGDVFVTLGTLAQISSETGITERMLKYYTYTSHQRRH
                     PNGRAVIKIEEEDNEN"
     gene            81757..82083
                     /locus_tag="VXF95_000207"
     CDS             81757..82083
                     /locus_tag="VXF95_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080818.1"
                     /translation="MMEELKQKVNAVYNWTVEDGKPQPPQQDLPQVVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKDWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGSEDE"
     gene            82076..82561
                     /locus_tag="VXF95_000208"
     CDS             82076..82561
                     /locus_tag="VXF95_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1080819.1"
                     /translation="MNKQELIDYCNVLKESKSRFINCIDVDRIIDTIKQLDEPEKVKV
                     PRFVAEWIEEARKACKDVVELFEFDFTNDEVRKWFMQERPFDLVARAWLDGYEVEEEK
                     RYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDANFGWVFDCEGIEIEGV
                     E"
     gene            82561..82749
                     /locus_tag="VXF95_000209"
     CDS             82561..82749
                     /locus_tag="VXF95_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase"
                     /protein_id="HEV1080820.1"
                     /translation="MSCSENLKKEKELTAAISNFKIEVLQNDDKLSSLSLSNIKRQAR
                     DLYECLVWLQYNAEESGR"
     gene            82746..83084
                     /locus_tag="VXF95_000210"
     CDS             82746..83084
                     /locus_tag="VXF95_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080821.1"
                     /translation="MSYDLEILVKIESGDYICIAEPKYSSPTYNLGRMFRVAMNWDFD
                     QDTTYNIADVLDNIQRGISELERYPEKYVQYEPENRWGTVSVALEVLKSLKECILEQD
                     IDTKYLYMRW"
     gene            83086..83346
                     /locus_tag="VXF95_000211"
     CDS             83086..83346
                     /locus_tag="VXF95_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1372 family protein"
                     /protein_id="HEV1080822.1"
                     /translation="MKRFIAIWILLSAGLNIWQSIYIKKLEEKRPIVVYKADNAGAEI
                     FGKVVEKGRHGKLYTLTIRDYGVFVVTKDVYDKVKVGDEVLL"
     gene            83343..83765
                     /locus_tag="VXF95_000212"
     CDS             83343..83765
                     /locus_tag="VXF95_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080823.1"
                     /translation="MTETIKLPDYYEPDWKNARYGSLEELKELLLFKRIVKWDKDFLL
                     LEDGTKVTIEMSESDCCASAGGEFQDVSLDAVITNIEIGELEEIPDHWGTGYKNKVTI
                     FHNQNPVAIANCEAEHNGYYYSVCSLVIGDIHFPVVNA"
     gene            83777..84214
                     /locus_tag="VXF95_000213"
     CDS             83777..84214
                     /locus_tag="VXF95_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080824.1"
                     /translation="MTPRYRAWIKTEKRMFFSDDILAIDYENKEIVTQQVYFENGLPD
                     DRDIYCYDFDEIELMQSTGLKDKNGKEIFEGDIVRTTRFLGRADEIGGFYEYDKEFIG
                     IVKQLEGSWVIDTGSDAVCLWTEIEENEIIGNIYENKEFGGRK"
     gene            84211..84582
                     /locus_tag="VXF95_000214"
     CDS             84211..84582
                     /locus_tag="VXF95_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080825.1"
                     /translation="MRPCKYPYSGRRKKQETPSPIFSARPIFDEVPIVEEVKVEFGVE
                     ASMGRIYPETLIHLDISGYGNRVHSVHRFPGILLSVGESIQLKMLFYKRLRNFTTDRF
                     LTFRESDWKFFIRDLVNEFKH"
     gene            84655..85059
                     /locus_tag="VXF95_000215"
     CDS             84655..85059
                     /locus_tag="VXF95_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1080826.1"
                     /translation="MNKAKELLKELQDLDMDIQSRIDEINELEAGLLSSPKWSEVKVQ
                     GGQTRKVDDVYTQLVVMKEAIEQDTKEVINRKLELGRMINRLKNPKYRAVLRMTYINK
                     GTADSVCYDLNMSRTTYYRLKNEAVLALEEVI"
     gene            85140..85222
                     /locus_tag="VXF95_000216"
     tRNA            85140..85222
                     /locus_tag="VXF95_000216"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:85171..85173,aa:Tyr,seq:gta)
     gene            85527..85967
                     /locus_tag="VXF95_000217"
     CDS             85527..85967
                     /locus_tag="VXF95_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HEV1080827.1"
                     /translation="MSGLRIKQKRFADEYIISGNATEAYKKAGYRVSSDRVAGVEGHK
                     LLKNPKIKSYIDERLKQLDSEKIADQQEVLGYLTSVMRGETQEQTLISIGELGQTITD
                     IDVGAKDRIKAAELLGKRHRLWTDKVEADVSGTVVFANESDIPD"
     gene            85945..87243
                     /locus_tag="VXF95_000218"
     CDS             85945..87243
                     /locus_tag="VXF95_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV1080828.1"
                     /translation="MSQTYQIKQNDIVVDLPKTVGAGYGQFWHSRSLYRVVKGSRGSK
                     KSKTTALNYVVRLLKYSWANLLVIRRYSNTNKQSTYTDFKWACNVLGVTHLFKFNESL
                     PEITIKATGQKILFRGLDDELKITSITVDVGSLCWAWFEEAYQIETEDKFSTVVESIR
                     GSLDVPDFFKQITVTFNPWNERHWLKRVFFDEETRRADTFATTTTYKCNEWLDEVDIK
                     RYEDLYHTNPRRARIVCDGEWGVAEGLIYENVTVKDFNKDELLQDSANKLCIGLDFGF
                     THDPTALCCSLINDTTKEIYVFDEAYKVGLITKEVAKMIKDKGYHRSQIIADSAESRL
                     IEELRSEHGISRIKESRKGKDSIMAGVSKLQGYAIYVHPDCKNIMDEFYSYCYQRDKE
                     GNWLNKPEDKNNHLMDALRYSLQCIEGGKATVRRRSDYGL"
     gene            87255..88724
                     /locus_tag="VXF95_000219"
     CDS             87255..88724
                     /locus_tag="VXF95_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1080829.1"
                     /translation="MYQYLTYPRDGYDEGSLKKDLIYKLITIHSTESSHLKKLKSYYL
                     GEHAILEHTRRNVNAPNYKTVANHAKDIADTATGYFMGNPIKYNNTADGDIDELLTAF
                     DGAEIDQVDAQNALNMAIYGRAYEYIYAKEGMAELDSTSIDPENTFMVYDDSIERKPL
                     FAVYYYEVKDDTKDTTKHQAEVFTENLHYHMVLRSTDSGTTQSEEATPHNLGQIPIIE
                     YRNNHFAIGDYEQQISLIDAYNSLMGNRVNDKEQAVESILVLYGTQLADTPEDAKVAM
                     KILSEEGLLELPGDSARAEFLKNTLDESATEILRTALKEDIYTFSHVPNLTDENFAGN
                     TSGVAMEFKLMGLEMITKTKEANYKRGLRQRIAIFAHYLGMKQIALESHSIVPQFSRG
                     LPKNLLEISQIVNNLEGKVTNRQLISLLPFVEDPDAELEALEEEKKKNMEDMPMFNQD
                     NTKPEDEVEDEESGVLGEEESQSDLPADGQGRKAGRSVR"
     gene            88633..90183
                     /locus_tag="VXF95_000220"
     CDS             88633..90183
                     /locus_tag="VXF95_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HEV1080830.1"
                     /translation="MKNQEYWAKRKANLIYQQMDKAEKQADQFDKVYQEAKTYLDKEV
                     NKIFDKFQRDYGLSQVEARQVLKNMKDKKNLNELRKVLEARPNDPNIQRLLADLDSPA
                     YSFRMKRLERLSDDLDRMRESIYHSEKTGSDAFYSDLMKDSYYKATFDLQQQTGLAYG
                     FSGLPESEIKHLQSFSWVGDGSTYSTNIWKNTGKLTSSIKDELLISLMTGRDTRETAQ
                     AIAERFNVGQNDARRLVRTESAFFHNQMELLNYEEADIEKYIFVAVLDKRTSRICQEH
                     DNQVYDRDKAVPGVNCPPMHPWCRSTTVGYDEDADYSKLKRRARNPETGKVEYVPADM
                     TYKEWYSKYVAKDVKNEIQDYKKSDKTVSRYNTPKLFSDVSNAWDEIGRGGLSKEQLV
                     DLLESEYELGNFSSDIAKLIGVSSAYIDVSSLATSLVRHGQQYSLDEFMLIKEAVQKP
                     YLILDNSERVEKSIISYVKIPNKDKVIMEAVMVPRDEMLVIHFNKVGIRQVKKNEKNM
                     STLYKKGK"
     gene            90334..90507
                     /locus_tag="VXF95_000221"
     CDS             90334..90507
                     /locus_tag="VXF95_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080831.1"
                     /translation="MDTARIGITNVEFSGTGENDSATVKLELNIYGADTFSAIELLPK
                     ILTDIHSLSYEVD"
     gene            90652..90864
                     /locus_tag="VXF95_000222"
     CDS             90652..90864
                     /locus_tag="VXF95_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080832.1"
                     /translation="MEEWKERFKKEYYELKERFQKLDMMIGKYEKGQLEFESKCPIDL
                     LKGQRSTMWNYLRILEQRAKIEEIKL"
     gene            91034..91618
                     /locus_tag="VXF95_000223"
     CDS             91034..91618
                     /locus_tag="VXF95_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HEV1080833.1"
                     /translation="MSEEINATVSTESTETVDTQGNVDSVQEEKHERTFTRAEIGKML
                     SAERSKWEAEQEAKENEAKKLAKMNADEKQKYQLDQREQELADREKAIARKELTAEAK
                     AMLSERDLPVELVNVVDLTSAETVSQSVAVLQKSWEQAVQKGVQEKLKGGAPMKQAPV
                     DSDGITKEEFARMGYQSRNELYQKNPELYKKLKG"
     gene            91625..92470
                     /locus_tag="VXF95_000224"
     CDS             91625..92470
                     /locus_tag="VXF95_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000123890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N4-gp56 family major capsid protein"
                     /protein_id="HEV1080834.1"
                     /translation="MTAGQTKLATMVNPEVMADMVAAKLPKLIKFTPLAYVETKLEGQ
                     PGSTLTVPAWEYAGDATEIEEGQAITPDQLTTKKTTMTIKKAGKGYEITDESLLSGLG
                     DPLGQATYQLGLAIANKIDNDLVAVAKTATQHITETPTTLEAIDKALDIFEDEEDAQY
                     VAIINPKDATKLKTAVAKEWIKGSELGANMVVSGTFGEVDGVQIVRSKKVDEGKGFLV
                     KVSPSQTQTDDANKYGAFVILLKRDVAIETDRDILKKTTVITGDEHYGVYLYDPTRVV
                     KFGGA"
     gene            92482..92664
                     /locus_tag="VXF95_000225"
     CDS             92482..92664
                     /locus_tag="VXF95_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho termination factor N-terminal
                     domain-containing protein"
                     /protein_id="HEV1080835.1"
                     /translation="MSLLLRRHYIQEEQVNQYSDLENKTLEELKDLAKEAGVAGAYKL
                     TKAEIVEVLEELKSEI"
     gene            92654..92842
                     /locus_tag="VXF95_000226"
     CDS             92654..92842
                     /locus_tag="VXF95_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080836.1"
                     /translation="MKFKIKQDFYDWESNVKRLAGEELEITEERYAELADNIASNGVA
                     ISDVLEEIFPKPEFLEED"
     gene            92844..93155
                     /locus_tag="VXF95_000227"
     CDS             92844..93155
                     /locus_tag="VXF95_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HEV1080837.1"
                     /translation="MSIELLKKLTGEEDTQLLMLLQTRATNLILSETNRTSLTPALSL
                     LIPEVAIELHNRSGAEGERSRTEGGIAVVYGENGLSTGLLQRIRMHRLARVAGHVFEA
                     E"
     gene            93136..93474
                     /locus_tag="VXF95_000228"
     CDS             93136..93474
                     /locus_tag="VXF95_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080838.1"
                     /translation="MFLKQSRLKPYPMRRFEKTVTEEGVAKEGYAKEAETVRLELWPA
                     SSKLQSELYGERVNDILNANANKSATIKVKDGVCIDSQTEVTHRVISKKVYTHHQVLE
                     LERVRATRGR"
     gene            93449..93964
                     /locus_tag="VXF95_000229"
     CDS             93449..93964
                     /locus_tag="VXF95_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000015942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1080839.1"
                     /translation="MSGLLGADRLIAKCRRLASKKTGEDIVLRAVHNATIKVVQADAR
                     RLAPARDGELITSIKTRAKMDGDKAIGEVYTNLKYAPYVEFGTGPKGQASHSGISPEV
                     SVTYKSSPWYVHEDQINVGPYHFQKIGEFYKMYGQPAQPYLYPALRDNQERVSKNISN
                     YVRRKIREQIK"
     gene            93961..94329
                     /locus_tag="VXF95_000230"
     CDS             93961..94329
                     /locus_tag="VXF95_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080840.1"
                     /translation="MINIKPVIYKELQKVADNVTDTYPSDWETFPVVIFLEEQNKPGD
                     WFDDQEQKSSIRYKVDIFDDTSTSELAVKINQIFESLGLRRTDCQDVPDPSHLRHKVM
                     RFEGVVDLDSELVFQFRMEN"
     gene            94332..94745
                     /locus_tag="VXF95_000231"
     CDS             94332..94745
                     /locus_tag="VXF95_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1080841.1"
                     /translation="MLANGITLSYGEAKGTYTKLVGLKEVPEFGIELEKVENTTLEDT
                     VKKYEFGIGDIGELEYKFSYNNSSATAPYRVLRKAADDKKKLYFEQAYPDGTKVNFEG
                     QVSVKLGGGGVNAVIEFTLKIALQSELEFTDGVGG"
     gene            94750..95130
                     /locus_tag="VXF95_000232"
     CDS             94750..95130
                     /locus_tag="VXF95_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001185634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080842.1"
                     /translation="MALKYTTWKVTDEKELKLRLTSHQAATVEEKIGMNLLKIFMPEA
                     GEEFTLPPLKVMLLLVHGALQQYEHGYSFEDVYDLYDEYVDNGGDQTTFMTEVLMPLF
                     EVSGFTPRGSKNKKTSKKKMTVVE"
     gene            95169..95519
                     /locus_tag="VXF95_000233"
     CDS             95169..95519
                     /locus_tag="VXF95_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080843.1"
                     /translation="MFLDIGGKPLDFWDLTVLEIREMIESYNRVKTQERKEKIIDSYR
                     LSQMISNHVSLLLSNDAKIVEFWEYAPELFVEEQQAVELERQKQALLLHKERMREFAE
                     RHNRKRKEEVNGNS"
     gene            95506..99120
                     /locus_tag="VXF95_000234"
     CDS             95506..99120
                     /locus_tag="VXF95_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080844.1"
                     /translation="MATLDELKVMIDAEIAPFRKKMKEVENQVKGTSDRVKNATAKVR
                     EQSNSIGSAFGKLAKFAGFAILGKKLLDVGMYSTQTALEVSASMNQIKRQMGESSQSF
                     LKWVNDNANAMNMGVGEATNYGAVYSNLFSGFIKDTNKLGAYTAKMLQTSAVVAEGSG
                     RTITDVMERIRSGLLGNTEAIEDLGINVNVAMIKSTEAFKRFSNGQSWDQLDFQTQQQ
                     IRLMAILEQATAKYGDTLSNSVNGRISLFKSLMKDAALNLGNSMLPIINAIMPVLNSF
                     AMVLKNVTAKLAEFIALMFNKKATVKDGVGGAVGDMGNAMKDAAGGAGDLADAVDDAG
                     DSAGGLADNLGDSAKNAKKAAKELLGLLGFDEINILQKPKDDDAGGSGGGGKGGKGKG
                     GGGGPFKDILPEVELTDMDNKFKSIFDGLGDKLKGLFDLFKKGFDAAFRPEGIERIKT
                     ALDQIAKTMGEIATDPRVVNAFNRMAEKIAYALGQVTGSITTIGLGIGVFLAESIANG
                     LGRQKERIIRALVALFDNVGNLSEAVGNIAQDFSSAFYDVITSTGAVRIGSAIVSTLL
                     SLTSTIVEVGSKLAGSLFKGFEKVVVTSAPKISSVFQSLLDTVAPVFESIERSVNKFG
                     DGLSRVYDEHVVPAINSIANAFNGLIDIIQILWEGSWKPFAEFLSNTFGISIETVADL
                     LGGIILEALKLLADTIKLVTDGFTAFSDWCKENKEIISTIASVIGTLATVWQGIKFLS
                     WAEQAGGLAGAFELLSSKVSFIVSGIKNLGLALKALTFDKLVSFGETIYLNALYAKDF
                     VVNSGKTIAQLGKTALELGKSALAWTAHTAKMGLATAAEFAHSVAAGVATAATWAFNA
                     ALAVLTSPITLVIAAIAALIGIGVLLYQNWDTVVEFAKTAWQGLCDFISGICQAIGEF
                     FSGLWTKLQEIFEPIGQWFSEKFQQAWDAIGNIFGNLGSWFGGRWNDSKNALAEANTW
                     LGDKFKSGRDKVNSAFEKVGSWFGDRWNDIKDGVKEADTWFGEKFESAKKKTQNPFQK
                     IGSWFGDRWKDMQDALKEIPNWFKNLFNDAMDNAKNIVKSGIDKLKSFFNFDWSLPKI
                     KLPHFNISGSFSLMPPRIPSFSVDWYARGGVFNSPSIIGVGEAGQEAVMPLERNTGWI
                     SILAQKLAERMPANNVPTGYSLPAGDIVIQIAGHEFGRVAIQEINKEHERAGQTLLKI
                     "
     gene            99129..99479
                     /locus_tag="VXF95_000235"
     CDS             99129..99479
                     /locus_tag="VXF95_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080845.1"
                     /translation="MAQLTINGVAVKPPKSFQVGIQDIDGETGRNANGDMMRDRITTK
                     RKLDCEWGMMTQGELSQLLHAVSSEFFEVSYPDPMDGQVTKTFYVGDRTAPRYTFTEK
                     FKPWSGAKFNLVER"
     gene            99484..>101608
                     /locus_tag="VXF95_000236"
     CDS             99484..>101608
                     /locus_tag="VXF95_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000339678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV1080846.1"
                     /translation="MDALTRRQFDRAMFAKERTLAIRVGDYASRDIKEASFEYGYIKG
                     DTYKPGGTCAGSGKITFTSIITTFNKLDTLHPEIGLLVGDTYQWVKMGEYFINDIEID
                     RNRNTTTLELMDGMFKLNREYVTDLHFPAEVREVIQEICLKTGIELANDYFGISAMRY
                     HIEQVPEGKKLSFRDMLSAMTQMIGMSCFFNREGKMEIRDLTESNITINADSYFLHGL
                     TKSEIEYQIAGITCKTDKKSLTVGMKTGRSLELDNVFMTQSALNDLYYKLKNLTYYPY
                     NLNYQGHLLLEVGQWVTIQTNKKETFKVPVLSQSFTFKGGLRGRISADSKAGNDTQYS
                     YEGTITKHIKQQDGIEAKIQAQIEAADKDFDQKVDKIKKDFNDQVELAKARAEEVKRE
                     LSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVARLEAFKSQ
                     TTSAQTALSGDLDALKRTIANDIRPKQAQAETEIAKQVEALSRTKNELAGVKSAQATY
                     EETTTRRLSELTNLANGKASKSELTQTAEELASKIASVQVGGRNYIRGTKRMMLARGL
                     WASGTFRPSGAGTAKTIDVSDSPVTGFDKAIRLTSSNARDQIGIAQDGFYISQGTYTM
                     SCWVKGRRGQKVKLQTYWQVHDNSGISPIFTLKDENWTKLSFTSARNRAGVASIGYVY
                     LVNAEVGEYLDVLAPQLEDGSLATSS"
BASE COUNT        31303 a        18182 c        22776 g        29347 t
ORIGIN      
        1 agatttagcc aaagagtcta ttagtgctag aataatagat tagaattatt ttagaaaaac
       61 gaagtgagca gcttataaat tcaagtcccc aaatagattc atactagtat cttttgcaaa
      121 aaataaaggg cgacttcctt catgaatatc aatttcatct ataaggaagg tagctaattg
      181 aactaactta tttattctgt ttgtcgctag aaaaatcaga cctccttgtg aagattgagg
      241 agatactgaa tgaaaatcaa agaagaaact agcaagctag tagcagattg cccaaaacac
      301 cgctttgagg ttgtagataa gactgacgta tataatccaa ggtgaagcga ctgtggtttg
      361 aagagatttt caaagagtat aggctagaga gtagtgtttt tatgtccttc tagtagaaaa
      421 tgctagacag aagaatgggg aacttggata ggagaaatag attgagaaag gaggttagaa
      481 gagatgatta ttacaaaaat tagccgttta ggaacttatg tgggagtaaa tccacatttt
      541 gcaacattaa tagattttct agaaaaaaca ggactagaaa atttaacaga aggttcgatt
      601 gctatcgatg gtaatcgatt gtttgggaat tgctttactt atctagcaga tggtcaagca
      661 ggggctttct ttgaaacaca ccaaaaatat ttggatattc atttagtttt ggaaaacgaa
      721 gaagccatgg ctgttacatc gccggaaaat gtaagcgtta cccaagaata tgatgaagag
      781 aaagatattg aattatacac agggaaagtg gaacagttgg ttcatttgag agctggtgaa
      841 tgcctcatca cttttccaga agatttacat caacccaagg ttcgtataaa tgatgaacct
      901 gtgaaaaaag ttgtctttaa agttgcgatt tcttaatgta gaaagagaag aacgatgaaa
      961 aaaatgagaa agtttttatg tctagctgga attgcgctag cggctgttgc cttggtagct
     1021 tgttcaggaa aaaaagaagc tacaactagt actgaaccac caacagaatt atctggtgag
     1081 attacaatgt ggcactcctt tactcaagga ccccgtttag aaagtattca aaaatcagca
     1141 gatgctttca tgcaaaagca tccaaaaacg aaaatcaaga ttgaaacatt ttcttggaat
     1201 gacttctata ctaaatggac tacaggttta gcaaatggaa atgtgccaga tatcagtaca
     1261 gctcttccta accaagtaat ggaaatggtc aactcagatg ctttggttcc gctaaatgat
     1321 tctatcaagc gtattggaca agataaattt aacgaaactg ccttaaatga agcaaaaatc
     1381 ggagatgatt actactctgt tcctctttat tcacatgcac aagtcatgtg ggttagaaca
     1441 gatttgttaa aagaacataa tattgaggtt cctaaaactt gggatcaact ctatgaagct
     1501 tctaaaaaat tgaaagaagc tggagtttat ggcttgtctg ttccgtttgg aacaaatgac
     1561 ttaatggcaa cacgtttctt gaacttctac gtacgtagtg gtggaggaag cctcttaaca
     1621 aaagatctta aagcagactt gacaagccaa cttgctcaag atggtattaa atactgggtt
     1681 aaattgtata aagaaatctc acctcaagat tctttgaact ttaatgtcct tcaacaagct
     1741 accttgttct atcaaggaaa aacagcattt gactttaact ctggcttcca tatcggagga
     1801 attaatgcca acagtcctca attgattgat tcgattgatg cttatcctat tccaaaaatc
     1861 aaagagtctg ataaagacca aggaattgaa acctcaaaca ttccaatggt tgtttggaaa
     1921 aattcaaaac atccagaagt tgctaaagca ttcttagaag cactttataa tgaagaagac
     1981 tacgttaaat tccttgattc aactccagta ggtatgttgc caactattag ggggattagc
     2041 gattctgcag cctataaaga aaatgaaact cgtaagaaat ttaaacatgc tgaagaagta
     2101 attactgaag ctgttaaaaa aggtactgct attggttatg aaaatggacc aagtgtacaa
     2161 gctggtatgt tgactaacca acacattatt gaacaaatgt tccaagatat cattacaaat
     2221 ggaacagatc ctatgaaagc agcaaaagaa gcagaaaaac aattaaatga tttatttgag
     2281 gctgttcagt agatgtaaaa gactagaaaa taggtgggct agtgagctga aaagttctag
     2341 cccaatcttg taaaagaagg gagaaggaga atggttaaag aacgtaattt aactcgctgg
     2401 atatttgttt tgccagctat gattatcgta ggattactct ttgtttatcc gtttttctcg
     2461 agtatttttt atagctttac caataagcat ttgattatgc ctaattataa atttgttggt
     2521 ttggctaact ataaagctgt gctatcagat cccaacttct ttaatgcgtt ctttaattca
     2581 attaagtgga ccgttttctc attagttggt caagttttag tagggtttgt attggcttta
     2641 gctcttcaca gagtacgcca cttcaagaaa ttatatagga ccttattgat tgttccttgg
     2701 gcatttccta ccatcgttat tgccttctct tggcagtgga ttctaaacgg ggtttatggc
     2761 tacttaccta atctaatcgt aaaattaggt ttaatggaac atacacctgc atttttgaca
     2821 gatagtacat gggcattcct atgtttggtg tttatcaaca tttggtttgg agcaccaatg
     2881 attatggtta atgtgctttc agctttgcaa acagtaccag aagaacaatt tgaggctgct
     2941 aagatagatg gtgcttcaag ttggcaggtg ttcaagttta tcgtctttcc acatattaaa
     3001 gtggttgtag gacttctagt tgttttgaga actgtatgga tctttaataa ctttgacatt
     3061 atctacctca ttactggtgg tggaccagcc aatgctacaa cgacgcttcc aatttttgct
     3121 tacaacctgg gttggggaac taaattgttg ggtcgtgctt cagcagttac agtattgctc
     3181 tttatcttct tggtggcgat ttgctttatc tactttgcta tcatcagtaa gtgggaaaag
     3241 gagggtagaa aataatgaag aagaaatcca gtatttattt agatattctc tcacatgtac
     3301 ttttagttgg tgcgaccatc gttgcaattt tcccattggt atggattatc atatcttctg
     3361 tcaaagggaa aggggaatta actcagtatc caacacgatt ttggcctgaa cagtttacat
     3421 tagattattt cactcatgtt atcaacgatt tgcacttcat tgataacatt cgaaacagtt
     3481 taatcattgc cttggctaca accctcattg cgattattat ttctgctatg gcagcctatg
     3541 gtattgttcg attctttcct aaattgggag caatcatgtc gagactactc gtcattacct
     3601 acattttccc accaattttg ttagcaattc cctattcaat tgccattgct aaagttgggt
     3661 taacaaatag tttatttggc ttgatgatgg tttatctatc ttttagtgtt ccatatgcag
     3721 tttggctctt agttggattt ttccaaacag ttccaattgg aattgaagaa gcggctagaa
     3781 ttgatggtgc aaataaattt gttacgtttt ataaggttgt gctaccgatt gtagcaccag
     3841 gtattgtagc aacagctatt tatacattta tcaatgcttg gaatgaattc ctgtatgcct
     3901 tgattttaat taacaataca ggaaagatga cagtagcagt agcccttcgt tcacttaatg
     3961 gttcagaaat actagactgg ggagatatga tggcagcgtc tgttattgta gttcttccat
     4021 caattatttt cttctctatc atccaaaata agattgcaag tggattatca gaaggatctg
     4081 tgaagtagac gaaagaagga aaaaaatgaa taaaagaggt ctttattcaa aactaggaat
     4141 ttctgttgta ggcattagtc ttttaatggg agtccccact ttgattcatg cgaatgaatt
     4201 aaactatggt caactgtcca tatctcctat ttttcaagga ggttcatatc aactgaacaa
     4261 taagagtata gatatcagct ctttgttatt agataaattg tctggagaga gtcagacagt
     4321 agtaatgaaa tttaaagcag ataaaccaaa ctctcttcaa gctttgtttg gcctatctaa
     4381 tagtaaagca ggctttaaaa ataattactt ttcaattttc atgagagatt ctggtgagat
     4441 aggtgtagaa ataagagacg cccaaaaggg aataaattat ttattttcta gaccagcttc
     4501 attatgggga aagcataaag gacaggcagt tgaaaataca ctagtatttg tatctgattc
     4561 taaagataaa acatacacaa tgtatgttaa tggaatagaa gtgttctctg aaacagttga
     4621 tacatttttg ccaatttcaa atataaatgg tatagataag gcaacactag gagctgttaa
     4681 tcgtgaaggt aaggaacatt acctcgcaaa aggaagtatt gatgaaatca gtctatttaa
     4741 caaagcaatt agtgatcagg aagtttcaaa tattcccttg tcaaatccat ttcagttaat
     4801 tttccaatca ggagattcta ctcaagctaa ctattttaga ataccgacac tatatacatt
     4861 aagtagtgga agagttctat caagtattga tgcacgttat ggtgggactc atgattctaa
     4921 aagtaagatt aatattgcca cttcttatag tgatgataat gggaaaacgt ggagtgagcc
     4981 aatttttgct atgaagttta atgactatga ggagcagtta gtttactggc cacgagataa
     5041 taaattaaag aatagtcaaa ttagtggaag tgcttcattc atagattcat ccattgttga
     5101 agataaaaaa tctgggaaaa cgatattact agctgatgtt atgcctgcgg gtattggaaa
     5161 taataatgca aataaagccg actcaggttt taaagaaata aatggtcatt attatttaaa
     5221 actaaagaag aatggagata acgatttccg ttatacagtt agagaaaatg gtgtcgttta
     5281 tgatgaaaca actaataaac ctacaaatta tactataaat gataagtatg aagttttgga
     5341 gggaggaaag tctttaacag tcgaacaata ttcggttgat tttgatagtg gctctttaag
     5401 agaaaaacat aatggaaaac aggtccctat gaatgttttc tacaaagatt cgttatttaa
     5461 agtgactcct actaattata tagcaatgac aactagtcag aatagaggag agagttggga
     5521 acaatttaag ttgttgcctc cgttcttagg agaaaaacat aatggaactt acttatgtcc
     5581 cggacaaggt ttagcattaa aatcaagtaa cagattgatt tttgcaacat atactagtgg
     5641 agaactaacc tatctcattt ctgatgatag tggtcaaaca tggaagaaat cctcagcttc
     5701 aattccgttt gaaaatgcaa cagcagaagc acaaatggtt gaactgagag atggtgtgat
     5761 tagaacattc tttagaacca ctacaggtaa gatagcttat atgactagta gagattctgg
     5821 agaaacatgg tcggaagttt cgtatattga tggaatccaa caaacttcat atggcacaca
     5881 agtatctgca attaaatact ctcaattaat tgatggaaaa gaagcagtca ttttgagtac
     5941 accaaattct agaagtggcc gtaagggagg tcaattagtt gtcggtttag tcaataaaga
     6001 agatgatagt attgattgga aataccacta tgatattgat ttgccttcgt atggttatgc
     6061 ctattctgcg attacagaat tgccaaatca tcacataggt gtactgtttg aaaaatatga
     6121 ttcgtggtcg agaaatgaat tgcatttaag caatgtagtt cagtatatag atttggaaat
     6181 taatgattta acaaaataaa ggagaaaaaa catggttaaa tacggtgttg ttggagcagg
     6241 gtattttgga gctgaattgg ctcgctacat gcaaaagaat gatggagcag agattactct
     6301 tctctatgat ccagataatg cagaggcgat tgcagaagaa ttgggagcaa aagtagcaag
     6361 ttccttagat gagttggttt ctagcgatga agtagattgt gttatcgtcg caactccaaa
     6421 taatcttcat aaggaaccgg ttattaaggc tgcacagcat ggtaaaaatg ttttctgtga
     6481 aaaaccaatt gcgctttctt atcaagattg tcgcgagatg gtagatgcgt gtaaagaaaa
     6541 caatgtaacc tttatggcag gacatattat gaatttcttt aatggtgttc atcatgcaaa
     6601 agaactcatt aatcaaggag ttatcggaga cgttctatat tgtcatacag ctcgtaatgg
     6661 ttgggaagaa caacaaccgt cagtatcatg gaaaaaaatt cgtgaaaaat caggtggtca
     6721 cttgtatcac cacatccatg aattggattg cgttcaattc cttatggggg gcatgcctga
     6781 aactgtaacc atgacaggtg gaaatgtggc ccatgaaggt gaacatttcg gtgatgaaga
     6841 tgatatgatt tttgtcaata tggaattttc taataagcgt tttgctttgt tagaatgggg
     6901 ttcagcttat cgttggggtg aacattatgt cttaatccaa ggaagcaaag gtgccatccg
     6961 cttagactta ttcaactgta aaggaactct taagctagat gggcaagaaa gctatttctt
     7021 gattcacgaa tcgcaagaag aagatgatga tcggactcgt atctatcata gtacagagat
     7081 ggatggagca attgcttatg gtaaaccagg taaacgtact ccattatggc tatcatctgt
     7141 cattgataaa gaaatgcgct atctgcatga gattatggaa ggagctccag tatcagaaga
     7201 atttgcaaaa cttttgacag gtgaagctgc cctagaagca attgctactg cagatgcttg
     7261 tacccagtct atgtttgaag atcgcaaagt aaaattgtca gaaattgtaa aataaatttt
     7321 ggtattctcc tatttatagg tcgacttgct cctctgaaag tacttttaga ggagctgttt
     7381 gactttgcta gtttttgaaa ctgaaatcta ttatactaca aactattgaa agcgttttaa
     7441 ttttaaggta taataatctc atagaaataa agaaaaggag gaaagaggat gccacagatt
     7501 agcaaagaag ccttgattga gcaaatcaaa gatggaatca tcgtttcttg tcaggctctt
     7561 cctcatgaac cgctttatac agaagcggga ggggtgattc ccttgctggt caaagcggct
     7621 gagcaaggtg gagcagtcgg tatccgagca aacagtgttc gcgatatcaa ggaaattaag
     7681 gaagtcacta aacttccaat cattgggatt atcaaacgtg attatccacc tcaggaaccc
     7741 ttcatcacgg ctactatgaa agaagttgat gaattggcag aactggacat cgaggtgatt
     7801 gctctggatt gtaccaagcg tgaacgctac gatggtttgg aaattcaaga gttcattcgt
     7861 caggttaagg agaaatatcc taatcagctt ttgatggctg atactagtat cttcgaagaa
     7921 gggctagcag ctgtagaagc aggaattgac tttgtcggaa caaccttatc aggctacaca
     7981 tcctacagtc caaaagtaga cggtccagat tttgaattga ttaagaaact ctgtgatgcc
     8041 ggtgtagatg tcattgcaga aggaaaaatt catacaccag aacaagccaa acaaatcctt
     8101 gaatatggag tgcgaggcat cgttgttggt ggcgccatta ctagaccaaa agagattaca
     8161 gaacgcttcg ttgctagtct taaataagat gtgaggggga gttttatgtt taaagtttta
     8221 caaaaagttg gaaaagcttt tatgttacct atagctatac ttcctgcagc aggtctactt
     8281 ttggggattg gtggtgcact ttcaaaccca accacgatag caacttatcc aatactagac
     8341 aatagtattt ttcaatcaat attccaagta atgagctctg caggagaggt tgtattcagt
     8401 aatttgtcac tacttctctg tgtgggatta tgtattggct tagcgaaacg agataaagga
     8461 accgctgcgt tagcaggagt aactggttac ttagttatga ctgcaacgat caaagctttg
     8521 gtaaaacttt ttatggcaga aggatctgca attgatactg gagttattgg agcattagtt
     8581 gtcggaatag ttgccgtata tttgcacaac cgatataaca atattcaatt accttccgct
     8641 ttaggattct ttggaggttc acgcttcgtt cctattgtta catcgttctc ttctatcttg
     8701 attggctttg tcttctttgt tatttggcca cctttccaac aacttcttgt ttctacaggt
     8761 ggatatattt ctcaggcggg tccaattgga acttttctat atggattttt aatgagactt
     8821 tctggagcag taggcttaca tcatataatt taccctatgt tttggtatac tgaacttggt
     8881 ggtgttgaaa ctgttgcagg acaaacagtg gttggagctc aaaaaatatt ttttgctcaa
     8941 ttagccgatc cggcccattc tggattattt acagaaggaa caaggttttt tgcaggtcgt
     9001 ttctcaacaa tgatgttcgg tttaccggct gcctgtttag cgatgtacca tagtgttcct
     9061 aaaaatcgtc gtaaaaaata cgcgggtttg ttttttggag ttgctttaac atcttttatt
     9121 accggtatta cagaaccaat tgaatttatg tttctattcg tcagtccggt tctatatgtt
     9181 gttcacgcat tccttgatgg tgttagcttc tttattgcag acgtcttaaa tatttcaata
     9241 ggaaacacat tttcaggagg tgtaatcgat ttcactttat ttggaatttt gcaggggaac
     9301 gctaagacga attgggttct tcagattcca attggactta tttggagtgt tttgtattat
     9361 attattttta gatggttcat tactcaattc aacgttctaa cgccaggacg aggagaagaa
     9421 gtagattcta aagaaatttc tgaatccgca gattcaactt caaatactgc agattattta
     9481 aaacaggata gcctacaaat tatcagagcc ttgggtggat caaataatat agaagatgta
     9541 gatgcttgtg tgacacgttt acgtgtagct gtaaaagaag ttaatcaagt tgataaagca
     9601 cttttaaaac aaattggtgc agttgatgtc ttagaagtga agggtggcat tcaagcaatc
     9661 tatggagcaa aagcaatctt atataaaaat agtattaatg aaattttagg tgtagatgat
     9721 taagtactta ctgacttaat aaaaaacaga ggagagtgat ggatgagtag gatgaaatga
     9781 aatcgcatac aagaaataaa gaactcatta tccaagttgg atacgcttat tacataggag
     9841 aatacaaatg aaatttagaa aattagcttg tacagtactt gcgggtgctg cggttcttgg
     9901 tcttgctgct tgtggcaatt ctggcggaag taaagatgct gccaaatcag gtggtgacgg
     9961 tgccaaaaca gaaatcactt ggtgggcatt cccagtattt acccaagaaa aaactggtga
    10021 cggtgttgga acttatgaaa aatcaatcat cgaagcgttt gaaaaagcaa acccagatat
    10081 aaaagtgaaa ttggaaacca tcgacttcaa gtcaggtcct gaaaaaatca caacagccat
    10141 cgaagcagga acagctccag acgtactctt tgatgcacca ggacgtatca tccaatacgg
    10201 taaaaacggt aaattggctg agttgaatga cctcttcaca gatgaatttg ttaaagatgt
    10261 caacaatgaa aacatcgtac aagcaagtaa agctggagac aaggcttata tgtatccgat
    10321 tagttctgcc ccattctaca tggcaatgaa caagaaaatg ttagaagatg ctggagtagc
    10381 aaaccttgta aaagaaggtt ggacaactga tgattttgaa aaagtattga aagcacttaa
    10441 agacaagggt tacacaccag gttcattgtt cagttctggt caagggggag accaaggaac
    10501 acgtgccttt atctctaacc tttatagcgg ttctgtaaca gatgaaaaag ttagcaaata
    10561 tacaactgat gatcctaaat tcgtcaaagg tcttgaaaaa gcaactagct ggattaaaga
    10621 caatttgatc aataatggtt cacaatttga cggtggggca gatatccaaa actttgccaa
    10681 tggtcaaaca tcttacacaa tcctttgggc accagctcaa aatggtatcc aagctaaact
    10741 tttagaagca agtaaggtag aagtggtaga agtaccattc ccatcagacg aaggtaagcc
    10801 agctcttgaa taccttgtaa acgggtttgc agtattcaac aataaagacg acaagaaagt
    10861 cgctgcatct aagaaattca tccagtttat cgcagatgac aaggagtggg gacctaaaga
    10921 cgtagttcgt acaggtgctt tcccagtccg tacttcattt ggaaaacttt atgaagacaa
    10981 acgcatggaa acaataagcg gctggactca atactactca ccatactaca acactattga
    11041 tggatttgct gaaatgagaa cactttggtt cccaatgttg caatctgtat caaatggtga
    11101 cgaaaaacca gcagatgctt tgaaagcctt cactgaaaaa gcgaacgaaa caatcaaaaa
    11161 agctatgaaa caatagtcct tagttattct ataaaaagta gttttttaaa gaacctaaga
    11221 gtgtataccc ccttttccct ctacacagat agtgtaagaa aagggggctt ttgtttaaaa
    11281 tgtaagaaac tgtcacgaaa ttaaaatgaa gttcttacat aagcgaatca taaaaaattt
    11341 cattttgatt ttaaaacagt tcaagaaagt caaaaaatta ttctatttga aagagaggtg
    11401 ccgactgtga aagtcaataa aatccgtatg cgggaaacag tgatttccta cgctttccta
    11461 gcaccagtat tattcttctt tgtcatcttt gtgttggctc cgatggtgat gggcttcatt
    11521 acaagtttct ttaactactc aatgactaaa tttgagtttg taggcttgga taactatatc
    11581 cgtatgttta aagatcctgt ctttacaaaa tctctgatta acacagttat tttggttatt
    11641 ggatctgtac cagttgttgt tctattctca ctctttgtag catctcagac ctatcatcaa
    11701 aatgtcattg ccagatcctt ctaccgtttc gtcttcttcc ttcctgttgt aacgggtagt
    11761 gttgccgtga cagttgtttg gaaatggatt tatgacccac tatcagggat tctaaacttt
    11821 gtccttaagt ccagccacat catcagccaa aacatttctt ggttgggaga taaaaactgg
    11881 gcattgatgg cgattatgat tattctcttg accacttcag ttggtcagcc catcatcctt
    11941 tatatcgctg ccatggggaa tattgacaat tcactggttg aagcggcgcg tgttgatggt
    12001 gcaactgagt ttcaagtttt ttggaagatt aaatggccaa gccttcttcc aacaactctt
    12061 tatattgcaa tcatcacaac aattaactca ttccagtgtt ttgccttgat tcagcttttg
    12121 acatctggtg gtccaaacta ctcaacaagt accttgatgt actaccttta cgaaaaagcc
    12181 ttccaattga cagaatacgg ctatgccaac acaattggtg tcttcttggc agtcatgatt
    12241 gctatcgtaa gctttgttca atttaaagta cttggaaacg acgtagaata ctaaagaaag
    12301 gagacagcta tgcaatctac agaaaaaaaa ccattaacag cctttactgt tatttcaaca
    12361 atcattttgc tcttgttgac tgtgctgttc atctttccat tctactggat tttgacaggg
    12421 gcattcaaat cacaacctga tacaattgtt attcctcctc agtggttccc taaaatgcca
    12481 accatggaaa acttccaaca actcatggtg cagaaccctg ccttgcaatg gatgtggaac
    12541 tcagtattta tctcattggt aaccatgttc ttagtttgtg caacctcatc tctagcaggt
    12601 tatgtattgg ctaaaaaacg tttctatggt caacgcattc tatttgctat ctttatcgct
    12661 gctatggcgc ttccaaaaca agttgtcctt gtaccattgg tacgtatcgt caacttcatg
    12721 ggaatccacg atactctctg ggcagttatc ttgcctttga ttggatggcc attcggtgtc
    12781 ttcctcatga aacaatttag tgaaaatatt cctacagagt tgcttgaatc agctaaaatc
    12841 gacggttgtg gtgagattcg taccttctgg agtgtagcct tcccgattgt gaaaccaggg
    12901 tttgcagccc ttgcaatctt taccttcatc aatacttgga atgactactt catgcaattg
    12961 gtaatgttga cttcacgtaa caatttgacc atctcacttg gggttgcgac catgcaggct
    13021 gaaatggcaa ccaactatgg tttgattatg gcaggagctg cccttgctgc tgttccaatc
    13081 gtcacagtct tcctagtctt ccaaaaatcc ttcacacagg gtattactat gggagcggtc
    13141 aaaggataat actctgagaa aatctcttca aactacgtca gcgtcacctt gccatactta
    13201 agtattgcct gcggttagct tcctagtttg ttcttcaatt ttcattgagt ataggaaaat
    13261 caatctatca agatacagaa gtatatttta tagatttaga gaatatagag gttataagtg
    13321 tctacaaaat ggagggtatg cagttacttt atgaagtttt gtcagacact tataaactta
    13381 agaatggttt tagttaacta tcagaaacga aggaaagagt atgatttttg acgatttgaa
    13441 aaacatcacc ttttacaaag ggattcatcc taatttagac aaggctatcg actatctcta
    13501 ccaacatcgt aaggattctt tcgaattagg aaagtatgat attgatggag ataaagtctt
    13561 tctagttgtt caggaaaatg tcctcaatca agctgaaaat gatcaatttg agtatcataa
    13621 gaactatgca gatttgcatt tgctggtaga aggacatgaa tattcgagct acggttcacg
    13681 tatcaaagac gaggcagtag cattcgacga agcgagtgac attggctttg ttcattgtca
    13741 tgaacactac ccactcttgt tgggttatca caattttgcg attttcttcc caggtgagcc
    13801 acatcagcca aatggttatg caggcatgga agaaaaggtt cggaaatatc tctttaaaat
    13861 tttgattgat taaaaatagg atgaattgtt tttttgtaaa gctttgacaa tactctacca
    13921 tgaaattgat ctttgtgagg tagggaaatg agaataaaat atttaaaaat tggtatcttc
    13981 taagtatgct gcaagagcta gtttcttgga tggacaggga attacagttg atgagatggc
    14041 ttggataatt aggggcattg tgaatggatt gattggtaga tacataaaat taggtactta
    14101 tgcagccaag tatggtatta gtatggcgcg ttcgatctta agtagggcag ctgcaactgc
    14161 agcagcaaga gtaggattat cgaccaagat ttctggatgg attttacgag tagctgtgaa
    14221 tgtagctgat gtatatggta attttgccaa caatattgct gcagcttggg atgcacatga
    14281 taaaattcct aacaatggtc gtataaactt ttaaaatgcg agaatgaaag cactttgtat
    14341 ttttttattg aatatgttag cttggacagt gcttgcaatg ataattcgtg gagggctaga
    14401 tggatttgat gagcatactt ggagtactat tttaattgct tcgctgttcg gggtatatga
    14461 ttataagccc atagataaaa atagaaaaaa gtccaaaaga aaaaagaaaa aagaaaaaat
    14521 agatttgttc atggtaggga cttatgaaag ctttactgac aaaaaagaaa acagtttaca
    14581 aagaaaaatg atggaggagc aaacatggca caaaaaggag taagccttat caaggcagca
    14641 tttgatacag acaactttct catgcgtttt agtgagaaag tcttggacat cgtgacagcc
    14701 aatcttcttt ttgtcgtctc ttgtttgccc atcgtgacga ttggagtggc taaaatcagc
    14761 ctctacgaga ccatgttcga agttaagaag agcagacggg tgcctgtttt taaaatctat
    14821 ctaagatctt tcaagcaaaa tctgaaacta ggtcttcagc tgggtttaat ggagttagga
    14881 attgtgtttc ttaccctttc agatctctat cttttctggg gtcaaacagc tctgcccttc
    14941 caattgctga aagccatttg tttaggtatt ctgatttttc ttactatcgt gatgctggct
    15001 agttacccta tcgcggcacg ttatgaccta tcttggaaag aaattcttca aaaaggattg
    15061 atgttggcta gttttaactt tccttggttc ttcctcatgt tagccattct tgtcctcatt
    15121 gtgatggttc tttatctgtc cgccttcagt ctactcttag gtggctcagt cttcttactt
    15181 tttgggtttg gactattggt ctttatccag actggattga tggagaaaat tttcgcaaaa
    15241 taccaatagg agccttattt ctgaaactac tttcaaacgc tccaaacgct attctataag
    15301 cgagaaacta aaatctaagt gtctataaga tattgaaagc cttttcggta aagtgtatac
    15361 taaagaagta aagaaaaatc tgctttagca gaaaataaaa ataataggag aaaatctatg
    15421 tcagatttga aaaaatacga aggtgtcatt ccagccttct acgcatgtta tgatgatcaa
    15481 ggagaagtaa gcccagaacg tacgcgtgcc ttggttcaat acttcattga taaaggtgtt
    15541 caaggtcttt atgtcaatgg ttcttctggt gaatgtatct accaaagtgt tgaagaccgc
    15601 aagttaatct tggaagaagt catggcggta gccaaaggta aattgaccat cattgctcat
    15661 gttgcctgca acaatactaa agatagtatg gaacttgctc gccatgctga aagcttggga
    15721 gtagatgcta ttgcaacgat tccaccaatt tatttccgct tgccagaata ctcagttgcc
    15781 aaatactgga acgatatcag ttctgcagct ccaaacacag actacgtgat ttacaacatt
    15841 cctcaattgg caggggttgc tttgactcca agcctttaca cagaaatgtt gaaaaatcct
    15901 cgtgttatcg gtgttaagaa ctcttctatg ccagttcaag atatccaaac ctttgtcagc
    15961 cttggtgggg aagaccatat cgtctttaat ggtcctgatg agcagttcct aggaggacgc
    16021 ctcatgggtg ctagggctgg tatcggtggt acttatggtg ctatgccaga actcttcttg
    16081 aaactcaatc agttgattgc ggataaggac ctagaaacag cgcgtgaatt gcagtatgct
    16141 atcaacgcaa tcattggtaa actcacttct gctcatggaa atatgtacgg tgtcattaaa
    16201 gaagtcttga aaatcaatga aggcttgaat attggatctg ttcgttcacc attgacacca
    16261 gtgactgaag aagatcgtcc agttgtagaa gcggctgctg ccttgattcg tgaaaccaag
    16321 gagcgcttcc tctaatataa aaggaggtat ttatgacata ctacgttgca attgatatcg
    16381 gtggaaccaa catcaagtat ggtttggttg atcaagaggg gcaacttctt gaatcgcatg
    16441 aaatgccaac tgaggcgcat aagggtggac ctcatatctt acaaaagacc aaagatatcg
    16501 tagctagtta tttagaaaaa ggcccagtag caggtgttgc catatcttct gctgggatgg
    16561 tggatccgga taagggtgag attttctatg ctgggcctca aatccctaac tacgcaggca
    16621 cccagttcaa aaaggaaatc gaagaaagct ttactattcc ttgtgagatt gaaaatgatg
    16681 tcaactgtgc aggtcttgct gaggcagtat ctggttcagg caagggagca agtgtgacac
    16741 tttgcttgac cattggaacc ggtatcggtg gttgcttgat tatggatagg aaagtcttcc
    16801 atggttttag caattcagcc tgtgaagtcg ggtatatgca tatgcaggat ggagcttttc
    16861 aggatctcgc ttctacaaca gctttagtga aatatgtagc tgaagcccat ggagaagatg
    16921 ttgatcagtg gaatggccga cgtatcttta aggaagctac tgaaggaaac aaaatctgca
    16981 tggaaggtat tgaccgtatg gttgactatc taggaaaagg tctggcaaat atttgttatg
    17041 tggccaatcc agaagtggtt attcttggtg gtggtatcat ggggcaagag gctatcctca
    17101 aacctaagat ccgcacagcc ttgaaagagg cattggtacc aagtttagca gaaaaaacac
    17161 gattagaatt tgcccatcac caaaatacag cagggatgtt gggtgcatat tatcatttta
    17221 agacaaaaca atcctagttt ggctcagcca aactaggatt ttcttacacg tttttgtcta
    17281 cgatagccgt tgagtttttt attttcccag tagctattaa agattttttc cttgctttcg
    17341 cgattgattt ccaaaaagta ggcataaatc aaatcgataa agaagagcat aggaagttga
    17401 gcggatattc gttggatgta ggagggttgg ctgtgggtgg ctacaagaac agtctctgta
    17461 taggtctggc tatctttatt gggaacactt gtaaagagta cagtctttgc ccccatctcc
    17521 ttggcatcta atagactatc taaaatagaa ggagttgagc ctgaaagtga gaaacccagt
    17581 actagacaat tttcatccat gatgctggtt gtccaggcaa agccgtcttg gtctgtcaaa
    17641 gcttcgcaga ccacacctag tcgcataaaa cgtaatttca tttcacgggc gacgaggcca
    17701 gaactccctg ttccaaagaa gtagatacgc tcagcatctt cgattagctg ggcaattcgc
    17761 tctagttgga tttcgtcaat caagtcttgt gtttgttccc tcatgttgct ataacttctg
    17821 aggactcgtt tggtcagtgg actgtgcttg gaaacttggt tggcttgatt ttctgcctga
    17881 tgttggtatt ggaaaataaa ttctcggtag ccagtaaagc cacacttttt agcaaagcgg
    17941 gtcaaagcag cttgagaaat atgtaatttt tgggtgactt gttgagaaga taaatcatct
    18001 gtaatcgttt cagcttgcaa aaaatagcga gcgatttctt gctctaggtc tgtcatttct
    18061 tcaaaatgtg aatcaatgat agttgcgata tctggtttgt ccatagggaa agctccttta
    18121 catgagtcat actggaagac tagatcaggg aatagtcaca cttcattata acacataata
    18181 taaggataga taaataaaaa cgcatctctg ttttaaaaac gaaaaaatcg aaaaagcttc
    18241 tctcttttcc ataattttct actcaaattg tggtacaatt aagagtaaga ttttaagtta
    18301 gaaatgagac tgatttgtat gagaaaattt aacagccatt cgattccgat tcggcttaat
    18361 ttattgtttt caatcgtcat tttactcttt atggccatta ttggtcgttt gttgtatatg
    18421 caggttttga acaaggattt ttacgaaaaa aagctagcct cagctagtca gaccaagatt
    18481 acaagcagtt cagcccgtgg ggaaatttat gatgctagtg gaaaaccttt ggtagaaaat
    18541 acgttaaagc aggttgtttc ctttacgcgt agcaataaaa tgacggctac agacttaaaa
    18601 gaaacagcta aaaagttact gacttatgtg agcatcagtt ctccaaattt gacagaacgc
    18661 cagctggcgg attactattt ggctgatcct gaaatctata aaaaaacagt ggaagctctc
    18721 ccaagcgaga aacgcttgga ttcagatggc aatcgtctat ccgaatcaga actgtataac
    18781 aatgcggtcg atagtgtaca aacgagtcaa ctaaactata cagaggatga aaagaaagaa
    18841 atctatcttt ttagtcagtt aaatgctgtt ggaaactttg cgacaggaac cattgcgaca
    18901 gatcctctaa atgattctca ggtggctgtt attgcctcta tttcaaagga gatgcctggc
    18961 attagtattt ctacttcttg ggatagaaag gttttggaaa cttccctttc ttctatagtt
    19021 gggagtgtat ccagtgaaaa agctggtctc ccagcggaag aagcagaagc ctatcttaaa
    19081 aaaggctatt ctctaaatga tcgtgtagga acctcctatt tggaaaagca atatgaagag
    19141 accttacaag gaaaacgctc ggtaaaagaa atccatctgg ataaatatgg caatatggaa
    19201 agcgtggata caattgagga aggtagtaag ggaaacaata tcaaactgac cattgatttg
    19261 gctttccaag atagcgtgga tgctttactg aaaagttatt tcaattccga gctagaaaat
    19321 ggtggagcca agtattctga aggtgtctat gcagtcgccc ttaacccaaa aacaggtgcg
    19381 gttttgtcta tgtcagggat taaacatgac ttgaaaacgg gagagttgac gcctgattcc
    19441 ttgggaacgg taaccaatgt ctttgtgccg ggttctgttg tcaaggcggc gaccatcagc
    19501 tctggttggg agaatggagt cttatcaggg aatcagacct tgacagacca accgattgtc
    19561 ttccaaggtt cagctccgat taattcttgg tacactcagg cttacggttc attcccgatt
    19621 acagctgtgg aagccttgga gtattcttct aatgcctata tggttcaaac ggctttgggc
    19681 attatgggtc agacctatca acccaatatg tttgttctaa ctaacaattt agaatccgcc
    19741 atggggaaac ttcgctcgac atttgcggaa tatggtcttg gagcctcaac aggcattgac
    19801 cttccagatg agtcaactgg ttttatacca aaagagtata attttgctaa ttacattacc
    19861 aatgcctttg gtcagtttga taactacact cctatgcaat tggcccagta cgttggaacc
    19921 attgccaaca acggtgttcg gattgcacct cacattgtcg aggggattta tggaaacaat
    19981 gaacaaggcg gcttagggaa cttaatccaa tctgttgaat ccaaggaaat gaataaaatt
    20041 aatatttctg agtctgatgt ttccatcctc caacaaggct tttatcaagt gtcacatggt
    20101 ggtagtgctt tgacaaccgg tcgtgccttt tcaaatggcg caagcgtatc gattagtggt
    20161 aaaacaggta ctgccgaaag ttatgttgag ggtggtcaag aagctaacaa tactaatgct
    20221 gtggcctatg caccatcaga taatcctcaa atcgctgtag ctgttgtctt ccctcataac
    20281 accaacctta caaatggtgt cggaccttcc attgcgcgcg atattatcaa cctctataac
    20341 caacatcatc caatgaatta gaaaggaaca tatgctttat ccaacaccta ttgctaagct
    20401 aattgacagt tattctaagt taccgggtat cgggattaag acggctacac gtctggcctt
    20461 ctatactatt ggaatgtctg atgacgatgt caatgaattt gctaaaaatc tcctttctgc
    20521 taagagagag ctgacctact gttccatctg cggtcgcctg actgatgacg atccttgctc
    20581 tatctgtacc gatccgactc gtgaccagac aacgatttta gttctcgaag atagtcgcga
    20641 tgtggcagcc atggagaata tccaagaata ccatggactc tatcatgtct tgcatggact
    20701 catttctccc atgaatggta ttagtccaga tgatatcaat ctcaagagcc tcatgactcg
    20761 tcttatggat agtgaagttt cagaggtaat cgtagcaaca aatgctacag cagatggtga
    20821 agcgacatcc atgtatcttt cacgtttgct caagccagct ggtatcaagg ttacgcgtct
    20881 agcacgaggt ctcgctgtcg gagcggacat tgagtatgcg gatgaagtga cgctcttacg
    20941 agccattgaa aatcgaacag agttgtaagt gtaggcaaat ttacgaactc cattcattta
    21001 taaaaaatca aagaggctga aaatcgttcc tatcggcctc tttttgtata gtgtgatgag
    21061 taggatcagg ttcaagtttt aaaaaaccaa gcaaatatga tatactaaag agcgagtatt
    21121 ctagtagaat taggacgaat aatatgaaac aaacgattat tcttttatat ggtggacgga
    21181 gtgcggaacg cgaagtctct gtcctttcag ctgagagtgt catgcgtgcg gtcgattacg
    21241 accgtttcac agtcaagact ttctttatca gtcagtcagg tgactttatc aaaacacagg
    21301 aatttagtca tgatccgggg caagaagacc gtctcatgac caatgaaacc attgattggg
    21361 ataagaaagt tgcaccaagt gctatctacg aagaaggtgc agtggtcttt ccagtccttc
    21421 acgggccaat gggagaagat ggctctgttc aaggattctt ggaagttttg aaaatgcctt
    21481 acgttggttg caacattttg tcatcaagtc ttgccatgga taaaatcacg actaagcgtg
    21541 ttctggaatc tgctggtatt gcccaagttc cttatgtggc tatcgttgaa ggcgatgatg
    21601 tgactgctaa aatcgctgaa gtggaagaaa aattggctta tccagtcttc actaagccgt
    21661 caaacatggg gtctagtgtc ggtatttcta agtctgaaaa ccaagaagaa ctccgtcaag
    21721 ccttagaact tgccttccga tatgatagcc gtgtcttggt tgagcaagga gtgaatgccc
    21781 gtgaaattga ggttggcctc ttgggtaact acgatgtcaa gagcacgcta ccaggagaag
    21841 ttgtcaagga tgttgccttt tatgactacg atgccaagta tattgataac aagattacta
    21901 tggatattcc tgccaaaatc agtgatgatg tggtggctgt catgcgtcaa aatgcagaaa
    21961 cagccttccg tgccattggt ggccttggtc tatctcgttg cgatttcttc tatacagata
    22021 agggagagat ttttctcaac gagctcaata ccatgccagg tttcacccag tggtctatgt
    22081 acccactact ttgggacaat atggggatca gctacccaga actaatcgag cgtttggttg
    22141 accttgccaa ggaaagtttt gacaagcgcg aagcgcattt gatataaaat gaaagagagg
    22201 gtagaagcca gaaccatcac tgcacggtga ctagagttct cggacttcag ccctttttaa
    22261 aggagtagaa atgaaattaa caatccatga aattgcccaa gttgttggag ccaaaaatga
    22321 tatcagtatc tttgaggaca cccagttaga aaaagctgag tttgatagtc gtttgattgg
    22381 aactggagat ttatttgtgc cacttaaagg tgcgcgtgat ggccatgact ttattgaaac
    22441 agcctttgaa aatggtgcag cagtaacctt gtctgagaaa gaggtctcaa atcatcctta
    22501 cattctagta gatgatgttt tgacagcctt tcaatcccta gcatcctact atcttgaaaa
    22561 aacgactgtt gatgtctttg ctgttacagg ttcaaatggc aagacaacga ctaaggatat
    22621 gttggcgcat ttactgtcaa caagatacaa gacctacaaa acacaaggca attacaataa
    22681 cgagattggc cttccttaca cagttcttca tatgcctgaa gggacagaaa agttggtctt
    22741 ggagatgggg caggatcact tgggagatat tcatctcttg tctgaattgg ctcgtccaaa
    22801 aacagccatc gtgaccttgg ttggagaagc ccatttggcc tttttcaaag accgttcaga
    22861 gattgctaag ggaaaaatgc aaattgcaga cggaatggct tcaggttcct tgcttttagc
    22921 gccggctgac cctatcgtag aggactattt gccaactgat aaaaaggtgg ttcgttttgg
    22981 tcaaggagca gagctggaaa ttactgactt ggttgagcgc aaagatagtc tgaccttcaa
    23041 ggccaatttc ttagagcaag tccttgattt gccagtgact ggcaagtaca atgcgacaaa
    23101 tgctatgatt gcatcctatg ttgccttgca agaaggagtt tcagaggagc aaattcatca
    23161 ggccttccaa ggtcttgaat tgacgcgtaa tcgtactgag tggaagaaag cagccaatgg
    23221 agcagatatc ctgtcagacg tatataatgc caatccaact gctatgaagc tgattttaga
    23281 gactttctct gccattccag ccaatgaagg tggcaagaaa attgcagtgt tggcggatat
    23341 gaaggagctt ggtgaccagt ctattcaact ccataaccag atgattttga gcctttctcc
    23401 agatgtgctt gataccgtta ttttctatgg agaaaatatt gctgaattag cccaattggc
    23461 tagtcaaatg ttcccaatag gccacgttta ctacttcaag aaaacagaag accaagacca
    23521 atttgaagac ctagtcaagc aggtcaaaga aagccttgga gtccacgacc aaatcctgct
    23581 caaaggctct aactctatga atctagccaa gttggtagaa agtttagaaa atgaaaccaa
    23641 gtgattttgt taagtatctg caaagaatga ttgcccttac agatactggc ttaaccttta
    23701 caaaagatcc ttttgaccgt gagcgctacg aagacttgcg aagtctgtta tctgaaatgt
    23761 tgaatcaggt atcagacctg gatgcagaag aagtagcaga agtcttgaaa ccaacttcag
    23821 cttatgcgac tcccttaatg gacgtccgtg cttggattgt tgaggatgag aagatttgtc
    23881 tggttagggg acaaggagag gatagttggg ctttgccagg tggctttggt gaagtcggct
    23941 attctccaac tgaaaatatt ctcaaggaaa ttgaagaaga aaccggtttt aaagccaaag
    24001 ttgaaagact gctagctgtt tttgatacca atcgtttcca actacagagc aaacaatatg
    24061 caaagtttgt ttttgaatgt aagcttctcg atggacaatt ccaagaaaat caagaaatcg
    24121 ctgcccttca attttttgca attgaccaac tgccgaattt atctgaaaaa cgcattacca
    24181 aggagcaaat cgagattctt tggcaggttt atcaaggtca gagggagcaa tatcttgact
    24241 aagaagatga ttatcgtatt tctaaatcca tttttgacaa ctagcatggt ataataatat
    24301 gcaggaaaat tttgaatcat gaggaagact agatgaattt atgggatatt ttctttacga
    24361 ctcaggcaac cgagccgccc aaatttgacc ttttttggta tgttagccta tttacgctct
    24421 tagccttaac cttttataca gcccatcgct atcgtgaaaa gaaggtttac caacgatttt
    24481 tccaaatctt gcagactgtt cagttaatcc ttctttatgg ttggtactgg gtcaatcata
    24541 tgccactgtc agaaagccta cccttttacc attgccgtat ggctatgttt gtggtactct
    24601 tgcttcctgg tcagtccaaa tataaacaat actttgcatt attgggaaca tttgggacat
    24661 tagcagcctt tgtttatcca gtgccagatg cttacccttt tccacatatc accattctat
    24721 cctttatctt tggtcattta gcactcttgg ggaactctct agtttatcta ttgagacagt
    24781 ataatgcgcg attgctggat gtgaagggaa tttttctcat gacctttgcc ctaaatgcct
    24841 tgatttttgt ggtcaatttg gtgacaggtg gcgattacgg atttttgaca aaaccgccat
    24901 tggttgggga tcacggtcta gtagctaatt atttacttgt ttcaattgtg ctggtagcta
    24961 ctatcagttt gactaagaaa atcttagaat tctttttagc tcaagaagca gaaaaaatga
    25021 ttgcaaagga agcttaacac agagctttct tttttgctct tagagagttt ttacaagcag
    25081 cttataaaat aagaatttct gaatagacaa actcaaaaaa tggctgggaa atttaggaaa
    25141 aaagcaagca cgattaaatt ttttgtgtta taatattttg tgaatagcta tgcctatgtt
    25201 tagctatgga ataatacgaa gtgcgaaact tggaagatag agaggaagcg atgtaatggc
    25261 tagagaaggc ttttttacag gtctagatat tggaacaagc tctgtcaagg tgcttgtggc
    25321 cgagcagaga aatggtgaat taaatgtaat tggcgtgagt aatgccaaaa gtaaaggtgt
    25381 aaaggatgga attattgttg atattgatgc agcagcaact gctatcaagt cagccatttc
    25441 ccaagcggaa gaaaaggcag gcatttcgat taaatcagta aatgtcggct tgcctggtaa
    25501 tcttttgcag gtagaaccaa ctcaggggat gattccagta acatctgata ctaaggaaat
    25561 tacggatcaa gatgttgaaa atgttgtcaa atcagctttg acaaagagta tgacacctga
    25621 ccgtgaagtc attaccttta ttcctgaaga atttattgtg gatggtttcc aagggattcg
    25681 tgacccacgt ggcatgatgg gggttcgcct tgaaatgcgt ggtttgcttt atacaggacc
    25741 tcgtactatc ttgcacaatt tgcgtaagac ggttgagcgt gcaggtgttc aggttgaaaa
    25801 tgttatcatt tcaccactag caatggttca gtctgttttg aacgaagggg aacgtgaatt
    25861 tggtgctaca gtgattgata tgggggcagg tcaaacgact gtcgctacaa tccgtaatca
    25921 agaactccag ttcacacata ttctccaaga aggtggagat tatgtaacta aagatatctc
    25981 caaggttttg aaaacctctc gcaaattagc ggaaggcttg aaactgaatt acggggaagc
    26041 ctatccgcct cttgcaagca aagaaacctt ccaagtagag gttattggag aagtagaagc
    26101 agtcgaagtg acggaagcct acttgtcaga aattatttct gcacgaatca agcacatcct
    26161 tgaacaaatc aagcaagaat tagatagaag gcgtctattg gacctccctg gtggtattgt
    26221 cttaatcggt gggaatgcca ttttaccagg tatggttgag cttgctcagg aagtctttgg
    26281 cgtccgtgtc aagctttatg ttccaaatca agttggtatc cgtaatccag cctttgcgca
    26341 tgtgattagt ttatcagaat ttgcgggtca attaacagaa gttaatcttt tggctcaggg
    26401 agcgataaaa ggtgagaatg acttaagtca tcagccaatt agttttggtg ggatgctgca
    26461 aaaaacagct cagtttgtac aatcaacgcc tgttcaacca gctcctgctc cagaagtaga
    26521 gtcggtggcg cctacagaac caatggcgga tttccaacaa gcttcacaaa ataaaccgaa
    26581 attagcagat cgtttccgtg gcttgatcgg aagcatgttt gacgaataaa gaggaaaaat
    26641 aaattatgac attttcattt gatacagctg ctgctcaagg ggcagtgatt aaagtaattg
    26701 gtgtcggtgg aggtggtggc aatgccatca accgtatggt cgacgaaggt gttacaggcg
    26761 tagaatttat cgcagcaaac acagatgtac aagcattgag tagtacaaaa gctgagactg
    26821 ttattcagtt gggacctaaa ttgactcgtg gtttgggtgc aggaggtcaa cctgaggttg
    26881 gtcgtaaagc cgctgaagaa agcgaagaaa cactgacgga agctattagt ggtgccgata
    26941 tggtcttcat cactgctggt atgggaggag gctctggaac tggagctgct cctgttattg
    27001 ctcgtatcgc caaagattta ggtgcgctta cagttggtgt tgtaacacgt ccctttggtt
    27061 ttgaaggaag taagcgtgga caatttgctg tagaaggaat caatcaactt cgtgagcatg
    27121 tagacactct attgattatc tcaaacaaca atttgcttga aattgttgat aagaaaacac
    27181 cgcttttgga ggctcttagc gaagcggata acgttcttcg tcaaggtgtt caagggatta
    27241 ccgatttgat taccaatcca ggattgatta accttgactt tgccgatgtg aaaacggtaa
    27301 tggcaaacaa agggaatgct cttatgggta ttggtatcgg tagtggagaa gaacgtgtgg
    27361 tagaagcggc acgtaaggca atctattcac cacttcttga aacaactatt gacggtgctg
    27421 aggatgttat cgtcaacgtt actggtggtc ttgacttaac cttgattgag gcagaagagg
    27481 cttcacaaat tgtgaaccag gcagcaggtc aaggagtgaa catctggctc ggtacttcaa
    27541 ttgatgaaag tatgcgtgat gaaattcgtg taacagttgt tgcaacgggt gttcgtcaag
    27601 accgcgtaga aaaggttgtg tctccacaag ctagaactgc tactaactac cgtgagacag
    27661 tgaaaccagc tcattcacat ggctttgatc gtcattttga tatggcagaa acagttgaat
    27721 tgccaaaaca aaatccacgt cgtttggaac caactcaggc atctgctttt ggtgattggg
    27781 atcttcgccg tgaatcgatt gttcgtacaa cagattcagt cgtttctcca gtcgagcgct
    27841 ttgaagcccc aatttcacaa gatgaagatg aattggatac acctccattt ttcaaaaatc
    27901 gttaagtaaa tgaatgtaaa agaaaataca gaacttgttt ttcgagaagt tgcagaggct
    27961 agtctgagtg ctcatcgaga gagtggttcg gtctctgtca ttgcagttac caagtatgta
    28021 gatgtaccga cagcggaagc cttgcttccg ctaggtgttc atcatatcgg tgaaaatcgt
    28081 gtagataagt ttctggaaaa atatgaagct ttaaaagatc gagatgtgac ttggcatttg
    28141 attggtacct tgcaaagacg taaggtgaaa gatatcattc aatacgttga ttatttccat
    28201 gcattggact cagtaaagct agcaggggaa attcaaaaaa gaagtgaccg agtcatcaag
    28261 tgtttccttc aagtaaatat ttctaaagaa gaaagcaaac acggtttttc gagagaggaa
    28321 ctgctggaaa tcttgccaga gttagccaga ctagataaga ttgaatatgt tggtttaatg
    28381 acgatggcac cttttgaggc tagcagtgag cagttgaaag agattttcaa ggcggcccaa
    28441 gatttacaaa gagaaattca agagaaacaa attccaaata tgcctatgac cgagttaagt
    28501 atgggaatga gtcgtgatta taaagaagcg attcaattcg gttccacttt tgttcgtata
    28561 ggtacatcat tttttaagta ggagagaacc atgtctttaa aagatagatt cgatagattt
    28621 atagattatt ttacggagga tgaggattca agtctccctt atgaaaaaag agatgagcct
    28681 gtgtttactc cagtaaattc ttcacaggaa ccggctctcc caatgaatca accttcacag
    28741 tcggctggta caaaagagaa caatatcacc agacttcatg caagacaaca ggaattggca
    28801 aatcagagtc agcgtgcaac ggataaggtc attatagatg ttcgttatcc tagaaaatat
    28861 gaggatgcaa cagaaattgt tgatttattg gcaggaaacg aaagtatctt gattgatttt
    28921 cagtatatga cagaggtgca ggctcgtcgt tgtttggact atttggatgg agcttgtcat
    28981 gttttagctg gaaatttgaa aaaggtagct tctaccatgt atttgttgac accagtgaat
    29041 gttattgtaa atgttgaaga tatccgttta ccagatgaag atcaacaggg tgagttcggt
    29101 tttgatatga agcgaaatag agtacgataa tgattttttt aattcgtatg atttataatg
    29161 cagtggatat ttactccctg attttggtag ccttcgctgt catgtcttgg tttccaggtg
    29221 cctacgaatc cagtttaggt cgttggattg tagcgttggt gaaaccagtg cttgctccct
    29281 tgcaacgcct gcctttacag atagcgggtc ttgatttatc tgtttgggtt gcgattgttt
    29341 tggttcgatt tttaggagaa aacctagtgc gttttctggc gatgatagga tgaataaagg
    29401 gatttatcag catttctcca tagaagatcg tccatttctt gacaagggaa tggaatggat
    29461 aaagaaggta gaagatagct atgctccttt tttaactcct tttatcaatc ctcatcagga
    29521 gaagctatta aagattttgg ccaaaaccta tggtcttgct tgtagcagta gtggggaatt
    29581 cgtctcgagt gagtatgttc gagttttatt atacccagat tatttccaac cagagttttc
    29641 agattttgaa atatctctcc aggaaattgt gtattccaat aaatttgaat atttaacgca
    29701 tgctaagatt ttagggacag tcatcaatca attagggatt gaacggaaac tttttggaga
    29761 tatcctagta gatgaagaac gggcgcagat tatgattaat cagcagtttc ttcttctctt
    29821 tcaagatgga ctaaagaaaa ttggtcgtat acctgtttcg ctggaggaac gtcctttcac
    29881 cgagaaaata gataagctag aacagtatcg agaactggat ttatctgtgt ctagttttcg
    29941 attagatgtt cttttatcaa atgttttgaa actatctagg aatcaagcaa accagttgat
    30001 tgaaaagaaa cttgtccaag taaattatca tgtggtagac aaatcagatt acactgttca
    30061 agttggagac ttgattagtg tgagaaaatt tggtcgcttg agattacttc aagataaggg
    30121 acaaacgaaa aaagagaaga aaaaaataac cgtccagtta ttattaagta agtgaggaat
    30181 agaatgccaa ttacatcatt agaaataaag gacaagactt ttggaactcg attcagaggt
    30241 tttgatccag aagaagtcga tgaattttta gatattgtgg ttcgtgatta cgaagatctt
    30301 gtgcgtgcga atcatgataa aaatttgcgt attaagagtt tagaagagcg tttgtcttac
    30361 tttgatgaaa taaaagattc attgagccag tctgtattga ttgcccagga tacagctgag
    30421 cgagtgaaac aggcggcgca tgaacgttca aacaatatca ttcatcaagc agagcaagat
    30481 gcgcaacgct tgttggaaga agctaaatat aaggcaaacg agattcttcg tcaagcaact
    30541 gataatgcta agaaagtcgc tgttgaaaca gaagaattga agaacaagag ccgtgtcttc
    30601 caccaacgtc tcaaatctac aattgagagt cagttggcta ttgttgaatc ttcagattgg
    30661 gaagatattc tccgtccaac agctacttat cttcaaacca gtgatgaagc ctttaaagaa
    30721 gtggttagcg aagtacttgg agaaccgatt ccagttccaa ttgaagaaga accaattgat
    30781 atgacacgtc agttctctca agcagaaatg gaagaattac aagctcgtat tgaggtagcc
    30841 gataaagaat tgtctgaatt tgaagctcag attaaacagg aagtggaagc tccaactcct
    30901 gtagtgagtc ctcaagttga agaagagcct ctgctcatcc agttggccca atgtatgaag
    30961 aaccagaagt agctccagtg catccgacag gtccaacacc agctacagaa actgttgatt
    31021 cagcaccggg atttgaagca ccgcaagaat ctgttacaat tttataagaa atattctgag
    31081 aacaatatct tatccttata ttcccagcga gcaggagatg gtgtgagtcc tgcattccct
    31141 atcgataaga ttatcctctc aaaaactcaa gtctgaatct agtaagattt gacgttcccc
    31201 acgttacggg ataagaggga gaaagactaa aactttttcc gaataaaggt ggtaccacga
    31261 ttttcgtcct ttttggaagt cgtggttttt aatttgttat tatttataaa ggagatacca
    31321 tgaaactcaa agacaccctt aatcttggga aaactgaatt cccaatgcgt gcaggccttc
    31381 ctaccaaaga gccagtttgg caaaaggaat gggaagatgc aaaactttat caacgtcgtc
    31441 aagaattgaa ccaaggaaaa cctcatttca ccttgcatga tggccctcca tacgctaacg
    31501 gaaatatcca cgttggacat gctatgaaca agatttcaaa agatattatt gttcgttcta
    31561 agtctatgtc aggattttac gcaccattta ttcctggttg ggatactcat ggtctgccaa
    31621 tcgagcaagt attgtcaaaa caaggtgtca aacgtaaaga aatggacttg gttgagtact
    31681 tgaaactttg ccgtgagtac gctctttctc aagtagataa acaacgtgaa gattttaaac
    31741 gtttgggtgt ttctggtgac tgggaaaatc catatgtgac cttgactcct gactatgaag
    31801 cagctcaaat tcgtgtattt ggtgagatgg ctaataaggg ttatatctac cgtggtgcca
    31861 agccagttta ctggtcatgg tcatctgagt cagcccttgc tgaagcagag attgaatacc
    31921 atgacttggt ttcaacttcc ctttactatg ccaacaaggt aaaagatggc aaaggagttc
    31981 tagatacaga tacttatatc gttgtctgga caacgactcc atttaccatc acagcttctc
    32041 gtggtttgac ggttggtgca gatattgatt acgttttggt tcaacctgct ggtgaagctc
    32101 gtaagtttgt cgttgctgct gaattattga ctagcttgtc tgagaaattt ggctgggctg
    32161 atgttcaagt tttggaaact taccgtggcc aagaactcaa ccacatcgta acagaacacc
    32221 catgggatac agctgtagaa gagttggtaa ttcttggtga ccacgttacg actgactctg
    32281 gtacaggtat tgtccataca gcccctggtt ttggtgagga cgattacaat gttggtattg
    32341 ctaataatct tgaagtcgca gtgactgttg atgaacgtgg tatcatgatg aagaatgctg
    32401 gtcctgaatt tgaaggtcaa ttctatgaaa aggtagttcc aactgttatt gaaaaacttg
    32461 gtaacctcct tcttgcccaa gaagaaatct ctcactcata tccatttgac tggcgtacta
    32521 agaaaccaat catctggcgt gcagttccac aatggtttgc ctcagtttct aaattccgtc
    32581 aagaaatctt ggacgaaatt gaaaaagtga aattccactc agaatggggt aaagtccgtc
    32641 tttacaatat gatccgtgac cgtggtgact gggttatctc tcgtcaacgt gcttggggtg
    32701 ttccacttcc tatcttctac gctgaagatg gtacagctat catggtagct gaaactattg
    32761 aacacgtagc tcaacttttt gaagaacatg gttcaagcat ttggtgggaa cgtgatgcca
    32821 aagacctctt gccagaagga tttactcatc caggttcacc aaacggcgag ttcaaaaaag
    32881 aaactgatat catggacgtt tggtttgact caggttcatc atggaatgga gtggtggtaa
    32941 accgtcctga attgacttac ccagccgacc tttacctaga aggttctgac caataccgtg
    33001 gttggtttaa ctcatcactt atcacatctg ttgccaacca tggcgtagca ccttacaaac
    33061 aaatcttgtc acaaggtttt gcccttgatg gtaaaggtga gaagatgtct aaatctcttg
    33121 gaaataccat tgctccaagc gatgttgaaa aacaattcgg tgctgaaatc ttgcgtctct
    33181 gggtaacaag tgttgactca agcaatgacg tgcgtatctc tatggatatt ttaagccaag
    33241 tttctgaaac ttaccgtaag attcgtaaca ctcttcgttt cttgattgcc aatacatctg
    33301 actttaaccc agctcaagat acagtcgctt acgatgagct tcgttcagtt gataagtaca
    33361 tgacgattcg ctttaaccag cttgtcaaga ccattcgtga tgcctatgca gactttgaat
    33421 tcttgacgat ctacaaggcc ttggtgaact ttatcaacgt tgacttgtca gccttctacc
    33481 ttgattttgc caaagatgtt gtttacattg aaggtgccaa atcactggaa cgccgtcaaa
    33541 tgcagactgt cttctatgac attcttgtca aaatcaccaa actcttgaca ccaatccttc
    33601 ctcacactgc ggaagaaatt tggtcatatc ttgagtttga aacagaagac ttcgtccaat
    33661 tgtcagaatt accagaagtt caaacttttg ctaaccaaga agaaatcttg gatacatggg
    33721 cagccttcat ggactttcgt ggacaagcac aaaaagcctt ggaagaagct cgtaatgcaa
    33781 aagttatcgg taaatcactt gaagcacact tgacagttta tccaaatgaa gtggtgaaaa
    33841 ctctactcga agcagtaaac agcaatgtag ctcaactttt gatcgtgtct gagttgacca
    33901 tcgcagaagg accagctccg gaagctgccc ttagcttcga agatgtagcc ttcacagttg
    33961 aacgtgctgc tggtgaagta tgtgaccgtt gccgtcgtat tgacccaaca acagcagaac
    34021 gcagctacca ggcagttatc tgtgaccact gtgcaagcat cgtagaagaa aactttgcgg
    34081 aagcagtcgc agaaggattt gaagagaaat aagattgaaa agtctaggca aaattcaatt
    34141 tgagaagaaa agacaactaa ttttatagtc tattaaacgc attgtatcac gtttttgaac
    34201 acctgatacg atgcgttttt atttattttg aaaatttgtg aggtgtgact ttttatactc
    34261 aacaagaatc aaagagaaac ttagcaagct aacagtagta agataaaata ggaatttgat
    34321 attagggata agattggtaa atagtgtaat atttttacaa caataaattt atatagttat
    34381 ttctggttgc tgaaaagtat tatattatat tttatttcat attatacaaa tttttatttt
    34441 ataatatcag aaaatacttt tttaaaaaag caaatatgat acaattttat ttgaaaaaaa
    34501 ataaaaaagg agattttatt atgaaatcaa aaagacttgc tttaattagt ggtatcgtcg
    34561 gtcttgtggg aggaatttta cttcttattt gtccttttgt cttgttggga acagcggtaa
    34621 atacagctgc tacaactctt aatggaggag ctactgcagg ggctttttca ggtgttgcct
    34681 tactcttgaa tgccttgaag attgcaaatc ttgttcttgg tatcattgct attgtttact
    34741 ataaaggaga taagcatgta ggtgcagctc cgtctgtact aatgattgtt tctggtgaag
    34801 ttagtctcat tccattctta ggatgggttg gggggattct tgctattatc ggaggatctc
    34861 tattccttgc aacattgaag aaattcaaat cagaagaata aaaggtattt tagcatgaaa
    34921 agaataaaaa cgtttatcgg tataggagta gctctattat ctctttctct tctagttgca
    34981 tgtggaacat aaagttcaaa gaatacttca acaagtaatg atgagaagac agtagcaaca
    35041 tccaatagtt caaaagaaac aatcactttc gatacaccgg ttgtaacaga cgatgcgatt
    35101 gaatcaatac gcacttatgc agattatata gatctttata aaaatatttt tgatgattat
    35161 tttactaaaa ctgaggaagg tttcaaaggc acagttatgg aaaataatga ctcgtttact
    35221 aaactaaaag agtcaactca aaaattattc gatgcgcaga aaaaaaggtt aaataatgaa
    35281 gatagaatag aaacaaccaa aaacaatgtg attgccaaac attgtcaaac agtcctttcc
    35341 tttttggttt tgactagctt ttttgtgaaa aattgtgtaa aatagaatag ataaacgagg
    35401 ggaaacctcg gaaaatttaa aggagaatcc atctaatggt aaaattggtt tttgctcgcc
    35461 acggtgagtc tgaatggaac aaagctaacc ttttcactgg ttgggctgat gttgatttgt
    35521 ctgaaaaagg tacacaacaa gcgattgacg ctggtaaatt gatcaaagaa gctggtatca
    35581 aatttgacca agcttacact tcagtattga aacgtgctat caaaacaact aacttggctc
    35641 ttgaagcttc tgaccaattg tgggttccag ttgaaaaatc atggcgcttg aacgaacgtc
    35701 actacggtgg tttgactggt aaaaacaaag ctgaagctgc tgaacaattt ggtgatgagc
    35761 aagttcacat ctggcgtcgt tcatacgatg tattgcctcc aaacatggac cgtgatgatg
    35821 agcactcagc tcacacagac cgtcgttacg cttcacttga cgactcagtt attccagatg
    35881 ctgaaaactt gaaagtgact ttggaacgtg ctcttccatt ctgggaagat aaaatcgctc
    35941 cagctcttaa agatggtaaa aacgtattcg taggagctca cggtaactca atccgtgccc
    36001 ttgtaaaaca catcaaaggt ttgtcagatg acgagatcat ggacgtggaa atccctaact
    36061 tcccaccatt ggtattcgaa ttcgacgaaa aattgaacgt cgtttctgaa tactaccttg
    36121 gaaaataaaa aattgtaagt ctagaattga tttctaggct ttttatgtta gtatggaagt
    36181 atgataagga ataaaaaaca agattatgta ctggcctaca agcaaccagc ttcaaccact
    36241 tacatgggtt gggaagaaga agctttaccg ataggcaatg gttctttagg agcaaaagta
    36301 tttggcctta taggggctga acggattcaa tttaatgaaa aaagtctctg gtctggaggt
    36361 ccacttcctg atagttcaga ttatcagggt ggaaatcttc aggatcagta tgtttttttg
    36421 gctgagattc ggcaggcttt ggagaagaga gattacaatc tggctaagga actggctgag
    36481 cagcacctaa ttgggccaaa aacgagtcaa tatgggacct atctgtcttt tggggatatt
    36541 cacattgagt tcagccagca aggtacgact ttgtctcagg tgacggacta tcagagacag
    36601 ctgaatatta gtaaggcact tgcgacgact tcttatgtct ataagggaac gcgatttgaa
    36661 cgtaaagctt ttgcgagttt tccagatgat ctcttggttc aatgttttac taaggaaggg
    36721 ttggaaactc tagattttac tatagaacta tccttgacct gtgatttggc ttctgatgga
    36781 aagtatgagc aggaaaaatc tgattacaag gagtgtaagt tggatattac tgattctcat
    36841 atcttgatga agggaagagt taaggataat gatctgcggt ttgctagtta tctagcttgg
    36901 gaaacggatg gagatattag agtttggtca gatagggttc agatatcagg agccagttat
    36961 gccaatctct tcttggccgc taagacggat tttgcccaaa atcctgctag caattatcgc
    37021 aagaaactag atttagagca acaggtgata gacttggtgg acacagctaa agaaaagggc
    37081 tatacccaat tgaaatcaag gcatatcgag gactaccaag ccttattcca gcgtgttcaa
    37141 ttggatttgg aagctgatgt tgacgcatcc actacagatg atttgttaaa aaattataag
    37201 ccacaagaag ggcaggcttt ggaggagctg ttcttccagt atggacggta tttattgatt
    37261 agttcgtcca gagactgccc agatgctcta ccagctaacc tacagggagt ctggaatgca
    37321 gtcgacaatc ctccttggaa ttcggactat cacttaaatg tcaatctgca gatgaattat
    37381 tggccagcct atgttaccaa tctcctagag gcggtctttc cggtcatcaa ctatgtagat
    37441 gatttgcgtg tctatggtcg tctagcggct gtaaagtatg caggaatcgt ctctcagaaa
    37501 ggtgaggaga atggttggtt ggttcatact caagcgactc cctttggttg gacggcacct
    37561 ggttgggatt actattgggg ttggtcacca gctgccaatg cgtggatgat gcaaaccgtt
    37621 tatgaaacct attcatttta tagggaccaa gactatctca gggagaaaat ttatcccatg
    37681 ttgagggaaa cggttcgttt ttggaatgcc tttttacata aggatcagca ggcgcagcgt
    37741 tgggtgtctt ctccgtctta ttccccagaa catgggccga tttcgattgg caatacttat
    37801 gaccaatctc tgatttggca gttatttcat gattttattc aggctgctca ggaattggga
    37861 ctggatgagg acttgttgac tgatgttaag gagaagtctg atttactaaa tcctttgcaa
    37921 atcactcaat ctggtcgaat cagggagtgg tatgaggagg aagagcagta ttttcaaaat
    37981 gagaaagtgg aggcccagca tcggcatgct tcccatctag tgggactcta tcctggcaat
    38041 ctctttagct acaagggaca agagtatatt gaagcggcgc gtgctagcct caatgatcgt
    38101 ggaaatggcg gcacaggctg gtccaaggct aataagatca atctctgggc gcgtttggga
    38161 gatggcaatc gagcccataa attattggca gagcagttaa agacatccac cttgccaaat
    38221 ctttggtgta gccatcctcc ttttcagata gatggtaatt ttggtgctac tagtggcatg
    38281 gcagaaatgt tactccagtc tcatgcagct tatctggtac ctctagctgc cctacctgat
    38341 gcttggtcaa caggttctgt ttcaggctta atggcacgtg gacattttga agtgagcatg
    38401 agctgggaag ataaaaaact cttacagttg accattttat caaggagtgg aggagatttg
    38461 cgagtttctt atccagatat tgagaagagt gtgattaaaa tgaatcaaga aaaaataaaa
    38521 gcgaaatgca tggggaaaga ttgtatttcg gtggcaacag cagaaggtga tcttgttcaa
    38581 ttttattttt aataaggatt taagaatata agcagttttc aactagttga aaaagcgtta
    38641 taatgataat aggaagtaat actcaatgaa aatcaaagag cacaaactag gaagctagcc
    38701 gcaggttgct caaaacagtg ttttgaggtt gcagatggaa gctgacgtgg tttgaagaga
    38761 gattttcgag gagtataatt tgtttgatag agggtgggtc tgatggctta tattgagatg
    38821 aaacactgtt acaagcgtta tcaggttggg gacacggaga ttgtggccaa tcgtgatgtg
    38881 aattttgaga ttgaaaaggg ggagctggtt attatccttg gagcttcagg tgcaggcaag
    38941 tcaacagttc ttaaccttct tgggggaatg gataccaatg atgaagggga aatctggatt
    39001 gatggtgtta atattgcgga ttatagttcc caccagcgca ccaattaccg tagaaatgat
    39061 gtggggtttg tttttcagtt ttataatcta gtttctaatc tgacagctaa ggaaaatgtg
    39121 gaactggctt ctgaaattgt gacagatgcc ttgaatcctg atcaggtctt gacagatgta
    39181 ggtctggctc atcgtctcaa taactttcca gcccagcttt ctggagggga gcaacagcga
    39241 gtctccattg cacgcgcggt agccaaaaat cctaaaattc tcctttgtga tgaaccgact
    39301 ggagccttgg attatcagac gggcaagcag gttttgaaaa ttctccaaga catgtctcgt
    39361 caaaagggag cgacggtgat catcgtgact cataatggag ctttggcgcc cattgctgat
    39421 cgcgtgattc aaatgcacga tgccagtgtc aaggatgtgg tgctcaacca gcatcctcag
    39481 gatattgaca gtttggagta ctagcatgat caagcgaaaa acttattgga aggacttaat
    39541 tcagtccttc acaggctcca aggggcgttt tttatccatc ttgatcctga tgatgttggg
    39601 atctctagcc ttagtaggcc tcaaagtaac cagtcccaac atggaggcga cagctaatgc
    39661 ttatttaaca actgctcaaa ccttggattt ggcagtcatg tctaactatg gcttggatca
    39721 agcagaccaa gaagaactaa aacagacgga gggcgcagag gtcgagtttg gctatttgac
    39781 agatgtgact atggataatg ggcaggatgc cattcggctg tactccaaac cagagcgaat
    39841 ttcaaccttt cagctaagaa agggacgact tcctcagtca gacaaggaaa tcgctttggc
    39901 cactcatttg caaggccaat acagcgtggg acaggagatt agttttaaag aaaaagaaga
    39961 ggatcattcc tctttaaaag accatactta taccattact ggttttgtgg attcggctga
    40021 aatcctctcc cagcgagata tgggctacgc aggaagtgga agtgggactc tgacagccta
    40081 tggggtgatt ttacctagtc agtttgatca gaaagtctac aatatagctc gtttgaaata
    40141 tcaagattta gcaggtttaa atgccttttc atcagcttat gaagaaaaat ccaagcaaca
    40201 tcaggaagac cttgaacaaa ctttatcaga taatggcaag gtacgtctgc aacttttgaa
    40261 aaaagaagga caagagtctc tagacaaggg gcaagagacc cttgacaagg ctcagactaa
    40321 tttgcaggaa ggcaagcgtc gtttagcagc tgctcaagct cgtatacagg ctcaagaaag
    40381 tcaactagcc ttgtttcctc aagttcagag agagcaggct agtgctcaac ttacccaagc
    40441 caagcaggaa ttgggcaagg aagaggacaa actaaagcaa gctgaacaaa atctagccca
    40501 agaaaaggaa aaattagaaa aacatcagca agtcttggac gatttggcgg agccaaggta
    40561 tcaggtctat aatcgtcaga ccatgccagg tggtcagggc tatcttatgt atagcaatgc
    40621 ttcatccagt attcgagcag tgggcaatat ctttcctgtg gtactttatg ccgtagcatc
    40681 catagtgacc tttacgacca tgactcgctt tgtagacgaa gagcgaactc atgcagggat
    40741 ttttaaggcc ttgggttacc gtagtaagga tattatcacc aagtttctcc tttatggact
    40801 agtagctggg actgtcggaa cggctctagg tagtatactt ggtcattatt tgctagccag
    40861 tgtaatttca agtgtcatta caaaaggcat ggtggtggga gaaacccaga ttcagttcta
    40921 ttggacctat agcttactag ctcttgtctt gagttggttg gcgagtgtgt taccagccta
    40981 tctggtggct tggagggaac ttcatgccga agcagcccag cttctacttc ctaaacctcc
    41041 tgtcaaagga gctaaaatct tattggagcg tatcggtttt atctggcgtc gtctcagttt
    41101 tactcataag gtaacagccc gcaacatctt tcgttataag cagagaatgt tgatgacaat
    41161 ctttggtgtg gcaggttctg tagctctgct ctttgcaggt ttgggaatcc aatcttctgt
    41221 agcaggagtt ccgtctaaac agtttcaaca aatccaacag tatcagatgc ttgtctctga
    41281 aaatcctagt gcgaccgatc aggacaaggt agagctagca gaagtgttga aagggcagga
    41341 gatactagcc taccagaaaa tctattctaa aacgctagac aaggatttca aaggcaaggc
    41401 tggtcttcaa aacattactc ttatgatgat agagaaggaa gatttgactc cctttatcca
    41461 tcttcaacat catcagcagg agctgacatt aaaagatggc atcgttatta cagctaaact
    41521 cgcccagctg gcaggtgtca aggttgggca gactttagaa attgaaggta aggaactaaa
    41581 ggtcgctgct attactgaga actacgttgg tcactttatt tatatgagtc aggctagcta
    41641 tgagcaactt tacggacagc taccccaagc caacacttat ctggtctcat taagggatac
    41701 cagtgcaact agtatcgaaa gtcaggcggg cttgcttatg aatcaatctg cggtgtccag
    41761 cgttgtccaa aatgtttcag ccattcgact cttcgactct atcgctagct cactcaatca
    41821 gaccatgacc atcttggtca tcgtatcggt tctattagct attgtcatcc tttacaattt
    41881 gaccaatatc aacgtagctg agagaatccg tgaactctcc actatcaagg ttctcggttt
    41941 tcataataat gaagtcacac tctacattta ccgtgagacg attgtgctgt cccttgtggg
    42001 aatcgtactt ggtctggtag ctggtttcta tttacaccaa tttttgattc aaatgatttc
    42061 gccttcgact attctctttt atccgcaggt aggctgggaa gtctatgtaa tcccagtggt
    42121 agcagtaagc atcattttga ccttgcttgg tttcttcgtc aattattatc tgagaaaggt
    42181 tgatatgtta gaagccctga aatctgtaga gtaaggtagt tatttttagc tgattgaact
    42241 tctatttact aatattcaaa aatcctccgt ttcaaagagc agggaactct ttgtgacaga
    42301 ggattttttc tatagggctt tagcagctgc aattgcggct tcgaagtttg gctcagaatt
    42361 gatattatcc acgtattcaa cgtagcgaat cgtattgtca gtatcgagga caaagactgc
    42421 gcgtgctaat aggtgccatt cgttgatcaa gagggcataa tcgtgcccga aagaatggtc
    42481 aaagtagtct gaaagcataa tggcattgtc aaggccttca gcaccgcacc aacgtttttg
    42541 agcaaaaggt aggtccattg aaacagtcaa tacgaccgtg ttgtccagtc cagccaattc
    42601 ttcattaaaa cgacgtgttt gagttgagca gatgcctgta tcgatagaag gaacgacact
    42661 caagactttt ttcttgccat caaaatcagc cagagatttt ttagaaagat ctgttgtagt
    42721 aagagaaaaa tcaagcgcct tgtcgccgac ttgtagttgt ttacctgtaa agctcacagg
    42781 atttccgaga aaagttacca taggatactc caatcttttt tcttccattg tatctgaaac
    42841 agtcagaatt ttccaatgat ttgaccggaa atgtgggcat agaaaaaacg ccagctcaca
    42901 tgagaatgac gtttttcaaa ggcttatttt gccaatcctt cagcaatctt gtcaaggttg
    42961 tatttcatca tgctgtagta gctgtcgcct tctttacctt gttctgcgat agagtcagta
    43021 aagatttgtg cgtagattgg gatgtttgtg tcttgagaaa cggttttcat tggacggtca
    43081 tccacacttg attctacaaa gagtgatgga acttttgttt ggcgaagttt ttcaaccaag
    43141 gtcttgattt gttcaggagt tccttcttct tcagtattga tttcccagat gtaggcactt
    43201 ggaacaccat aggctttaga gaagtatttg aatgctcctt cgctggttac aatgagtttc
    43261 ttttcagcag ggatcttatt aaatttatcc ttactttctt tatcaagttt gtctaactta
    43321 tcagtatatt ctttgagatt tttttcatag aattctttat tgttagggtc tttggcgctc
    43381 aattgtttgg cgatattttt agcaaaaata ataccgtttt caaggttaag ccaagcgtgt
    43441 gggtcttctt ttcctttttc attttgacct tcaaggtaga taacatcaac gccgtcgctg
    43501 actgcgaagt agtctttgtt ttcagttttc ttggcatttt ctaccaattt tgtaaaccaa
    43561 gcattgccac ctgtttcaag gttgataccg ttatagaaaa tcaaatcagc ctcagaagtt
    43621 ttcttaacgt cttcaggaag tggttcgtat tcgtgtgggt cttgcccaat cggaacgata
    43681 ctatgaaggt caattttgtc accagcaata tttttagtaa tatcagcgat gattgagttt
    43741 gtagcaacaa cttttagttt ttgaccagaa gttgtatctt tttttccgct agcacatgct
    43801 acaagaatga ttgcagaaag aaagagaacg agtaatgtac ctaatttttt cattagatcc
    43861 tccaatttat tagggctttg ccccttattt taacaaatgt ttatttttca gtttcaaata
    43921 tcgttgtttg ggagcgataa agaagctaat gagaaagaaa ctagcagctg taagcacgat
    43981 actagaacct gccgcaacat taaaactata gccaataaag agtcccaaaa ctgaagcagt
    44041 agctccgaag gttgaggaaa ggaaaatcat acttttcaga ctattagcat acagataagc
    44101 agttgcagct ggggtaatca gcatggctac aatcaggata gttccgacac tttgcatggc
    44161 tgtcacagac acgagagtca ggagtaccat gagaaggtag tgatagaaat tgacaggcat
    44221 tcccatggct ttagccaaga gttcatcaaa ggaagttatc aagagttgct tgaagaaaat
    44281 ccagattaac aagaggatgg ctgcccccac acccatagta ataaacatat ccgtatcttg
    44341 gacggccaga atattaccaa aaaggatatg gaaaaggtca gttgaacttt tagcgacacc
    44401 aatcaagatg ataccgaggg ctaagaaaga agaaaaggta atgccgatgg cggtatcgct
    44461 tttgataatc gagtttcctt tgatgtaggt aatgatgatg gcagctagca atccaaagac
    44521 aatggctccg ataaagaagt caaggcccaa gatgaaggag agggctacac ctggtaagac
    44581 agcatgtgaa atggcatctc ccatgagtga catcccgcgt agaataatga aacatcccac
    44641 agctccagct acaatcccga cgacaatagc tgttatcaag gcattttgta ggaaatggaa
    44701 tttttgcaat ccatcgataa attctgcaat cataggtcac ctccattgaa aaagagttga
    44761 ttaccgtaag cttcttttag attggtttcg gtaaaagttt cttttgttgg accaaaggca
    44821 atcacttctc gattgacaag taagacttga tcgaagtagt ggggaatctt gctgaggtcg
    44881 tggtgaacga tgagaaccgt cttcccagct tttttcaaat ctctcagcgt attcatgatg
    44941 atttcctcac tgacagagtc aatcccagca aagggttcat ccaagaggat atagtcggct
    45001 tcctgcacca aacatctggc aatcaagacc cgctggaatt gacctccaga cagttgacta
    45061 atttgacgtt cagcgtagtc agctaggccg acgatttcaa gggcctcttg cactttcttc
    45121 caatgtttag cctttaaact tcgaaagaga ggaatagagg gaaatagtcc taacgagacg
    45181 cattccttga ccttgatggg aaagttgtag tcgatattga ttttttgttc gacataggca
    45241 attcggtgta aggatttttt aacttccttg tcatcgagaa atgcctgacc ttgatgtggg
    45301 ataattccca acataccttt taatagtgtt gatttcccag cgccgtttgg accaatgatg
    45361 ccggtaattg ttggtccatg gagcactagt gaaatatcct taagtgccaa cgtttctttg
    45421 taggagacac tgaggttttc gatacgtatc ataaacttgt attcctcctg tctcttaata
    45481 tacattaaaa aaaaaattaa gtcaagttaa tttttgaaaa aattaaaata ataactgaaa
    45541 aatagattct aaaaataact ttcaggataa atttctaaat tataaaacgc atagtatcaa
    45601 gtgtaaaaaa cttggaatta tgcgttttat catggaaaga ttttttataa tagctaaaaa
    45661 ataatagtta aatggttatt aattgcattc cctagtgatt tttgttaaga taaatgcaaa
    45721 tacaaatgaa agcgagaaca agatgacacg ttatcaagat gatttttatg atgctatcaa
    45781 tggagaatgg caacagacag ctgaaatccc agcagataag tctcaaactg gaggttttgt
    45841 tgatttagac caggaaattg aagacctgat gctggcgaca acagacaagt ggttagcagg
    45901 tgaagaagtg cctgaggatg ctatcttgga aaactttgtc aaataccacc gcctagttcg
    45961 tgattttgac aagagagaag ctgacggtat cacacctgtc ttaccactcc ttaaagaatt
    46021 ccaagaattg gaaacttttg cggattttac agctaaacta gcagagtttg agcttgcagg
    46081 aaaaccaaac ttccttcctt ttggtgtatc gccagacttt atggatgcta gaatcaatgt
    46141 tctatgggct agcgctccaa gcacaatctt gccagatacg acctactatg cagaagaaca
    46201 tcctcagcgc gaagagctct tgactctttg gaaagaaagc agcgcaaatc tcctcaaggc
    46261 ttatgatttc tctgatgaag aaattgaaga cttgctagaa aaaagacttg aattggaccg
    46321 ccgagttgcg gcagtggtgc tctctaatga agaaagttca gaatatgcta aactctatca
    46381 tccatattct tacgaagatt ttaagaaatt cgcgcctgcc ctacctttgg atgacttctt
    46441 caaagcagtt attgggcaat taccagacaa ggttattgta gacgaggaac gtttctggca
    46501 agcagcagag caattctaca gtgaggaagc ctggtctctc cttaaagcaa ccttgatttt
    46561 gagtgttgtc aatctttcaa ccagctattt aacagaggat atccgtgttt tgtctggtgc
    46621 ctacagccgt gccctttctg gagttccaga ggcaaaagat aaggtcaaag cagcttatca
    46681 tctagcacaa gaacctttca agcaagccct gggtctttgg tacgcccgtg agaagttctc
    46741 tccagaagcc aaggcggatg tggagaaaaa agtggcaacc atgattgatg tctataagga
    46801 gcgtctgctt aagaatgact ggctcactcc agaaacctgt aaacaggcta tcgtgaagct
    46861 caatgtgatc aaaccttata ttggctatcc agaagaattg cctgcacgtt acaaggataa
    46921 ggtagtgaat gaaactgcca gtctttttga gaatgctcta gcctttgcgc gtgtggaaat
    46981 caagcacagt tggagtaagt ggaaccagcc tgtagactat aaggaatggg gcatgcctgc
    47041 tcatatggtc aatgcctact acaatcctca gaagaacctg attgtctttc cagcggccat
    47101 tttacaggcg cctttctatg acttgcatca gtcatcttct gctaactacg gtggtattgg
    47161 ggcagtgatt gcccatgaaa tttcccacgc ctttgatact aacggggctt cctttgacga
    47221 aaatggtagc ctcaaggatt ggtggacaga gagcgactat gctgccttta aggagaaaac
    47281 acaaaaagtc attgaccaat ttgatggaca ggattcttat ggagcaacca ttaacggtaa
    47341 attgactgta tcagaaaacg tggctgactt gggaggaatc gcagcagcgc ttgaagcagc
    47401 taagagagaa gcagacttct cagcagaaga gttcttctac aacttcggtc gcatctggcg
    47461 catgaaaggt cgaccagaat ttatgaaact tttggctagc gtcgatgtgc acgcaccagc
    47521 caaactccgt gtcaatgtgc aagtaccaaa cttcgacgat ttctttacaa cctatgatgt
    47581 caaagaagga gacggaatgt ggcgttcacc agaggagcgc gtgattattt ggtaatacaa
    47641 aaaatctagt catcagaaaa aaggcatcca atcacgtgtg aaaaccttga taggatgcct
    47701 tttgtaatag aaagatttgc tggatagttt acttaaattt cgattgtcat catcttgcta
    47761 gaaaaaggga ttgaaggcct tttcgtgagc gatagtagta gctggaccat gtcctggata
    47821 gacatcgtag tttggtaggg tgaagagttg ggtctggata ctatgaagga gttgctccat
    47881 gctaccagtc ggaaggtcgg tccgtccgat agtttcgcgg aatagagcat ctcccgtcaa
    47941 gactaggtga gcatcaggaa agactaggga aacaccaccg atagagtgcc ctggggtcgg
    48001 tagaacctta aaacgaaatt cctctagttg gtattcttcg tgaaagacaa aggtgtgttc
    48061 tgcaggtttt gtgaccacat ctgccatatc atcgtggcga gggagaccgg agagattatc
    48121 gacaggagtg tagagccagc tggcttcgct ctctgcgata tagacaggag gattgccaaa
    48181 cgtctcgcga accaagtcca gactcatgat atggtcataa tgggcgtggg tcaagagaat
    48241 agcacagatc ggtttgttga tcttctcgat tgtctgacga atggcttccc aatgactacc
    48301 aggatcgacg acgatgaggt gcttttcgcc ttctagataa taggtatttt cataggcaac
    48361 aggattcacg gttttatgga ttttcatact agctccaatc tcaaagaatg tactaatact
    48421 cttcgaaaat ctcttcaaac cgcgtcaact ttatctgcaa cctcaaagca gtgctttgaa
    48481 cagcctgcgg ctagctttct agtttgctct ttgattttca ttgagtataa attaagtata
    48541 gcacagttag ggagaatagg taaggattta aaatgaactt aaaaaccagc atgactagat
    48601 gaagacaggc tggttatcaa tttatcaata ttggaaaggt gtcaattgcc cttcataggt
    48661 tgcataaact ccgtcattag cttgtttgat agacgtgatg tttagagtgc taccgtagtt
    48721 ggcttatcat ttgtcgctat attcactata agttatccta ctgggcaggt tctggtcgtt
    48781 agcatagtat tgaacgagtt ttttatagct ttgctggctg aataggaaca ggcagcaaac
    48841 tcctaacatt aggagagcaa agatagaaat agcagttttt ttcataggta ttctccttat
    48901 aaactaaagg atagaagaaa gtatcttgag gatttttata ctcttcaaaa atctcttcaa
    48961 accgcgtcaa caatctcttc aaaccgcgtc aacgtcgcct tgccgtatat atgtgactga
    49021 ctttgtcagt cttatctaca acctcaaagc agtgctttga gcaacctgcg gctagtttcc
    49081 tagtttgctc tttgattttc attgagtatt aattccaaaa tccagtcaag gtaccagtgt
    49141 atgtgatacg agttccaccg tttatctttc gtatcttcaa tggaattggg gaaatcagaa
    49201 agtctttggg ttacaatatg gtttccgttc ttctatctct ccttctatca cctaagttta
    49261 aaatctaact tcgtagtata ttatgggcca ataattcaga attatcaagc aattttgaat
    49321 tatttttttc ttattctgtt ccaatctagt tttcatattc ttaaaaaagt gataaaatgg
    49381 taggaagaat tggagagtag agatgccgaa agaagtgaat ttaacaggcg aagaagttgt
    49441 cgctttaacc aaagaatatt taacggaaga ggatgttcat tttgtccata aggccttggt
    49501 ctatgctgtt gaatgccaca gtggtcaata tcgcaaatca ggcgagcctt atatcattca
    49561 ccctatccaa gtggcaggta ttttagctaa gctaaagctg gatgctgtaa cagtagcttg
    49621 tggattcttg catgatgtgg tggaagatac agatgcgacc ttggacgatt tggaaagaga
    49681 gtttggtcct gatgtgcggg tgattgttga cggagttacc aagcttggca aggtcgagta
    49741 caaatcgatc gaggagcaat tagcggaaaa tcatcgcaag atgctcatgg ccatgtctga
    49801 ggacatccgc gttattttgg tcaaactgtc tgaccgcttg cacaatatgc ggaccctgaa
    49861 acatcttcga aaagacaagc aggagcgtat ttccaaagaa accatggaaa tctatgcccc
    49921 acttgcccat cgtttgggga tttccagtgt caaatgggaa ttagaagact tgtctttccg
    49981 ttatctcaat ccaacggagt tttacaagat tacccatatg atgaaggaaa agcgcaggga
    50041 gcgtgaggcc ttggtggatg aggtagtcac aaaattagag gagtatacga cagaacgtca
    50101 cttgaaaggg aagatttatg gtcgtcccaa gcatatttac tcaattttcc gcaaaatgca
    50161 ggacaagaga aaacggtttg aggaaatcta tgatctgatt gctattcgtt gtattttaga
    50221 tacccaaagt gatgtttatg ccatgcttgg ttacgtgcat gaattttgga aaccgatgcc
    50281 aggtcgcttc aaagactata ttgccaaccg caaggccaat ggttatcagt ctatccatac
    50341 gactgtttat ggaccaaaag ggccgattga attccagatt cgaaccaagg aaatgcacga
    50401 ggtggctgag tacggggttg cggctcactg ggcttataag aaaggtataa aggggcaagt
    50461 taacagcaag gaatcagcta ttggaatgaa ctggatcaag gagatgatgg agctccaaga
    50521 ccaggctgat gatgctaagg aatttgtgga ctctgttaag gaaaactatt tggctgagga
    50581 gatttacgtt tttaccccag atggagctgt ccgttccctt cccaaagatt caggaccgat
    50641 tgattttgcc tacgaaatcc ataccaaggt cggtgaaaaa gcaactggtg ccaaggtcaa
    50701 tggccgcatg gttccactga caaccaagtt aaagacaggg gatcaggttg aaattatcgc
    50761 caacccgaac tcctttggac ctagccgtga ctggctcaat atggtcaaga ctagcaaggc
    50821 gcgcaataag attcgccagt tctttaaaaa ccaagataag gaattgtctg tcaacaaggg
    50881 tcgtgagatg ctgatggctc agttccaaga aaatggctat gtggcaaata aatttatgga
    50941 caagcgccac atggatcaag ttctgcaaaa gaccagttac aagacagaag actccctctt
    51001 tgcggccatt ggttttgggg aaatcggtgc gattaccgtc tttaatcgtc tgactgaaaa
    51061 ggaacgccgt gaggaagagc gtgccaaggc caaggctgag gcagaggagc ttgtcaaagg
    51121 tggcgaggtc aaggttgaaa ataaagaaac tctcaaggtc aagcatgagg ggggagtggt
    51181 tattgaaggt gcttctggtc tcctagtgcg gattgctaag tgttgtaacc ccgtgcctgg
    51241 tgacgatatt gttggctaca ttaccaaggg tcgtggtgtg gctattcacc gtgtggactg
    51301 tatgaacctg cgtgcccaag aaaactacga gcaacgtctc cttgatgtgg aatgggaaga
    51361 ccagtactct agctcaaata aggagtatat ggcccatatc gatatctacg gtctcaaccg
    51421 tacaggactg ttgaacgatg tactgcaagt tctttcaaat acaaccaaga atatttcaac
    51481 ggtcaatgcc caaccaacca aggatatgaa gtttgctaat atccatgtgt ccttcggtat
    51541 tgccaacctc tctacactga ccacggttgt cgataaaatt aagagtgtgc cagaagttta
    51601 ctctgtcaaa cggaccaacg gctagttgtc ctagctctta ctagaaaggc tattatgaaa
    51661 atcattatcc aacgggttaa aaaagcccaa gtgagtatag aaggccagat tcagggaaaa
    51721 atcaatcagg gacttttatt gctggttggt gttggaccag aggaccaaga ggaagatttg
    51781 gactatgctg tgagaaaact ggtcaatatg cggatttttt cagacgcaga aggcaagatg
    51841 aacctgtctg tcaaagatat tgaaggagaa atcctctcta tttctcagtt taccctcttt
    51901 gcggatacta agaaaggcaa tcgtccagcc tttacagggg cagctaaacc tgatatggca
    51961 tcagacttct atgatgcttt caatcaaaaa ttagcgcaag aagtgcccgt tcagacaggc
    52021 atctttggag cagatatgca ggttgaactg gttaataacg gacctgttac cattatccta
    52081 gatactaaaa agagataaga aagaccaagc ccagtcggct tggtctttct catcgatcat
    52141 aaaatactcc aaaaagaaat cggttcttga tatgcttggg ggaagtctct tttcaggctt
    52201 tggcagatgc gataggaagg gatgagatat cctaggatga ggagagttcc ctgaaggaaa
    52261 agtggaatat cacttaaaga caccaaggag agaatcatca ggctatccca taggagaatt
    52321 tgtaaagcaa aacgccagaa tctcggtcta atctgggaat agagttaact aaagtggtca
    52381 caaagttggt ttgaaagata ggtcaatagc acaggatgaa agaaaatgag ccaaccacta
    52441 taaatcaaaa tccagtccca agtaagcccc ccttttaaat gtcaaaaatg ccagcatgat
    52501 tccatcaatg acaaggagtt gaatggtttt gatgaagatg atttttttca tgctaaaacc
    52561 tccttttttc atctgttagt gacgtaatgc tttatataat tattatacag tattcagtcg
    52621 ggatatgaaa acgtttacta tcgtttttga tataaaaaat agataagaaa accctgaaaa
    52681 taaaactttc agggttggta ggggacttga gaaattagtt gattttctcg acatagagtt
    52741 gttttgcaat gtccatattc acttgtaaat cctcgtcgtt actgaggata gtgaaggtat
    52801 tgctgaagcc atcaaactgc ttgacttgga gctggtcacc gatgtgaagt gagtgcttgt
    52861 ccagataatg gagaatgtca aaactatcgt gcacccgagt caggcggtag gcgccagctt
    52921 ccttgatatc agctagtggg aggttattga tttcaacgag gagttctccc ttggcaggaa
    52981 tagttcctcc gtgggggcag gttttaggga aacctagcag tttatctagt ctttccacga
    53041 acaggtcaga gacagtgtgt tccaagacct cagcttcctc gtgaatctgg tcacttgtat
    53101 agtctaaatg atgaactaga aaaacttcaa tcaagcggtg cttacgatag agctcagaga
    53161 ccagtttgag accgaggtca gtcagtagat agccacattc cttgtccttt aggatgagat
    53221 tttcactttt cattcgtttg atcatttcag ttacggcagg gggagagact tgcatgcgag
    53281 ccgcaatttc cttgttggta atcttatgca ggtctatgcc aatttcataa atacatttta
    53341 gatagtcttc tttgtttggg gtcattcgtt tcctcttgtc taatatcttt atctagtata
    53401 tcaaaaaaag ctagatttct ctagctgtga ctttttatgt tatacttatt gcaagagaaa
    53461 aaacgaggag atggatatga cgaaaatagc tcttctttca gatattcatg gaaataccac
    53521 cgccttggag gctgttttgg cagatgctca gcagctagga gtggatgaat actggctttt
    53581 gggagatatt ctcatgccag ggacaggacg tagaaggatt ttggacttgt tggatcaact
    53641 accgattacg gctagagttt tgggaaactg ggaagacagt ctttggcatg gtgtccgtaa
    53701 ggaattggat agtactcgcc ctagtcaacg ctatctcttg cgccagtgcc agtatgtttt
    53761 agaggaaatt tccctagaag aaattgaagt gctccacaat caacctcttc aaattcatcg
    53821 tcagtttggg gatttgacgg tgggaattag ccatcatctg cctgataaga actgggggcg
    53881 agagttgatt catactggca aacaagagga gtttgaccgc ttggtgactc atcctccctg
    53941 tgatattgct gtttatggac atattcacca gcagttgctt cgttacggga ctggtgggca
    54001 attgattgtc aatccgggtt cgattggcca acctttcttt ttggacgctc agctacggaa
    54061 ggacttgcgg gcccagtata tgattttgga gtttgatgac aagggcctgg tagatatgga
    54121 cttccgacgg gtagattacg atgtggcagc tgaattgcag ctggctaaag acctgagact
    54181 tccctatttt gaggtttact atgaaagtct ggtcaatggg atccaccata ctcatcatca
    54241 ggaatttttg agagaattgg ctcagaaaga gggttgcgat cgggagttag acgactggtt
    54301 gaaaagtggt aacgattgac attacaacta aaaagggtat aataatagaa aaagaagagt
    54361 agaggcaggg tagcctcgta aaaaggagaa gaggatgcaa attccaagta gatttaccat
    54421 tgcaactcat atgctgataa tcattgccct cgaggggaag gaaagcaagg tgaccagtga
    54481 ttttctggct gctagtgttg gggtcaatcc tgtcattatc agaaagatct tgtcccagtt
    54541 gaagaaggca gagctgattt cagtagcgcg tggaacgggc ggaacagaga ttgtcaagga
    54601 ccttaaggat attagtcttt tagatgttta tcaggcggtc gaatgtcttg gtaagacagg
    54661 tcaactcttc agtttccatg acaatccgaa tccaaattgc cctgtaggag ctcatattca
    54721 tgatgttttg gatcaaaaat tggagagaat tcagttgact atggaggcag aacttggtca
    54781 gaccagtcta gaaaaagtcg tggccgatgc agagagtcag atgaaggatt aagagggata
    54841 aatgccctct ttttttcttt ggataattat gataaaatgt agctattaaa ggagtaagaa
    54901 atgtatctcg ttatagaaat tgtattagcc tttatagtgt cattttggaa ggataataga
    54961 agtttgtgga atccagtatt atttttatta tccctcattt caagttattt ttatctatcc
    55021 tacctttttt ataaaaatgg atacgagaat gttcagttag ctttttatgt atttgccttt
    55081 gtcttacttc cttttttgct ttttctaagt ggcatctttt taatctataa tggggtcatt
    55141 ttgttgaaac gagagggacg ttccaagccc cattatctct caatgctctt tgatttttat
    55201 tgactattag attctattta aaaagactta gaatgcacat gaaagtatgt attctaggtc
    55261 ttttgttttg tatacattta attttcaaga gtattatcta tttttccatg catggtaacg
    55321 agtatcaatc aataactggg taaggcgacc caaggtttct ctttcttctg gagtgaggga
    55381 ttgagcttgg acaaagagat gatgaatgta ttcaagcgcc tttaaggaag ccaagtcatt
    55441 gatagagcta ataccagcat caagaatagt gccaaagaag aggtcgaagt agagctgaag
    55501 ttcttcgtca gggactgtgg ccacccattc tttaaaggtt gtgtctactt gccggctatc
    55561 actgttggtc ttatccagtt gaacgaagtg cttgtcctca atctgccaac taaaggtatc
    55621 gtgctgggcg atgccaccca gggcagtact ctgaacgatg atttggtgag caggaatttc
    55681 cagcatcata ccgataatgg aaccttgtgg aatgaatatc ttgcttctat ccattatcct
    55741 ttgataaccc gcagtctgtg tcaattcttg atggagacca ggtgcatcaa atgtataaac
    55801 tgctgtgatc tgattttgca aactttgctc aatttggcta gcagcataga tagcgagatt
    55861 tcctcccttg gaatgcccag ccagaataac cttttgctta ggatgatggg caaaaaagtt
    55921 ctttaaatag cgaagggcgt gcttttgagc aggaatttcc ttcatatagg tcaggtggaa
    55981 atcttccttc cagccaatga tactgtcatc tgtcccacga aagacaatca gataggtatc
    56041 gaggctgaca cgataagtca tagccgcaaa ttgcttttgc agttcagggt cgatgtcgtt
    56101 gataaaatgg gagagtttgc aatttttgaa gcgcttgtgt tgagccaatt catctaataa
    56161 ttgaaggcga tttttgctag taagcatggt gggctctctt ggaacctgag gtgctagatc
    56221 taaaagacgt tgaggaagtg tggagaccag attatcaaag gagaggtagg tgatttctat
    56281 taaggttaga atgtctaact cattcaaggg aaggtcgtaa taagaatcat atgcgacatc
    56341 tttcagatag tcaaaaatat tggccataag agctcctttc tttttattta tcttagcaaa
    56401 tttccctcaa attagctagt agcatagcct gtttgtactg gctaaaaaca ggctatttca
    56461 aattcagttt cagaccatct agcatggaaa aatctgttat aataatggaa aaggagaagc
    56521 gcatgcacaa gattttatta atagaagatg atcaggtcat tcgtcaacag attgggaaaa
    56581 tgctctctga atggggattt gaagtggtcc tggtagaaga ctttatggaa gttttgagtc
    56641 tatttgttca gtcggaacct catctggtcc tcatggatat tggtttgccc ttgtttaatg
    56701 gttatcactg gtgtcaggaa atccgcaaga tttccaaggt acctatcatg tttctttctt
    56761 cgagagacca ggctatggat attgtcatgg caatcaatat gggggcggat gactttgtga
    56821 ccaagccttt tgaccagcag gttcttttag ctaaggttca gggcttgttg cgtcgttcct
    56881 atgagtttgg gcgtgatgag agtttgctgg aatatgctgg tgttatcctc aataccaaat
    56941 ccatggattt acattatcaa gggcaagtct tgaatttgac caagaatgaa ttccagattt
    57001 tacgcgtgtt atttgagcat gcaggcaaca tcgtagcacg tgacgacctg atgcgggaac
    57061 tttggaacag tgactttttc attgatgata ataccctctc tgtcaatgtg gctcgtttgc
    57121 gtaaaaagtt ggaggagcag ggattggtag gatttatcga gaccaagaaa ggaatagggt
    57181 acggattgaa gcatgcttga ttggaaacaa ttttttctag cctatctgcg ctcccgtagt
    57241 cgtcttttta tctatctgct ttctttggca tttcttgtct tactctttca gtttttattt
    57301 gccagtctag gaatttactt cctctacttt ttcttcttgt gttgctttgt aaccatatta
    57361 tttttcactt gggacatatt ggtggaaacg caggtctatc gccaggaact tctctatgga
    57421 gagagggaag ccaagtctcc tttggaaata gctttagcag aaaaattaga agcgcgtgag
    57481 atggaactct atcagcagag gtcaaaagca gaaagaaaac tgacggattt gctggattac
    57541 tataccttgt gggtccatca gataaagacc cccattgcag ccagtcaact cttagttgca
    57601 gaagtggtcg accgccaact gaagcagcaa ctagaacagg aaattttcaa aatcgactcc
    57661 tataccaacc tagttttaca gtacctgcgt ttagaaagtt tccatgatga tttggtctta
    57721 aagcaggttc aaattgagga cttggtcaag gaaataattc gtaaatatgc tcttttcttt
    57781 attcaaaaag gcttaaatgt caatctacat gaccttgata aagaaatcgt gacggataaa
    57841 aagtggctgc tagtggttat tgagcaaatc atctcaaaca gtctcaagta caccaaggaa
    57901 ggtggtctgg agatttatat ggatgaccaa gagctttgta tcaaagatac gggaatcggg
    57961 ataaaaaaca gtgatgtcct ccgagtattt gaacgtggct tttcaggata caatggccgt
    58021 ttgacccagc agtcctctgg acttggcctt tatctatcta agaaaatttc tgaagaactg
    58081 gggcaccaga ttcgtatcga gtctgaggtc ggaaaaggaa cgacagtgcg gattcagttt
    58141 gctcaagtga acttagtcct tgagtaaaaa tagatgagaa aaagcctcca gattggaggc
    58201 ttttatgcta gactcttatt tctcaacgcg tgatttgttg gcgatatcag ctaggatagc
    58261 ttgaacaaaa ttatcaactg agacagtttg tgtttctttt tggccgtagc gacgaacgtt
    58321 gactgtttcg tcttccattt ctttgtctcc aacaattaat tggtaaggaa tcttgctggt
    58381 ttgtgaagca cgaatcttga actgcatttt ttcattgcgc tcatctacgt ctgcacggac
    58441 accgcggtca cggagtttct tggccacttc ccaagcgtag tccacgtgtt tttcgttaga
    58501 tactgggatg agggttactt ggtgtggtgc cagccatgtt gggaaggccc ccttgtagtt
    58561 ctcaatcaag atagctgtga agcgttccat agttgagata accccacggt ggatcatgac
    58621 tggacggtga tcttcgccat cagctccgat gtatttgagg tcgaagcgtt ctggcaacaa
    58681 gaaatcaagt tggatagtag aaagggtttc ttcttttcca agggcagttt taatctggat
    58741 atccaatttt ggtccgtaga aggctgcttc accttcggct tcaaagtagt ccacgcccat
    58801 ttcatcaaga gctgcacgaa gcatggtttg ggcattttcc cacatctcat cgttatcaaa
    58861 gtacttatga gtatcttgag ggtcacgaag agagaggcgg aagcggtagt cagtcaagtt
    58921 gaagtcttca taaacatcga taatcaactg aagggcacgt tggaattctt cttggatttg
    58981 ttctggagta acgaataggt gaccgtcgtt gagtgacatt tcacgtacac gttgaaggcc
    59041 agtgagggca ccagattttt cgtaacggtg catcataccg atttcagcga tacggattgg
    59101 caattcacgg taagagtgaa catggtgttt gaaaacttgg atgtggtgcg gacagttcat
    59161 tggacgaagg acaaattctt ccccgtcacc catgtccatg gttgggaaca tgtcttcttg
    59221 gtaatgatcc cagtgaccag aagtcttgta aagctcaaca gaagcaagtg gtggagtgta
    59281 gacgtgttgg tagccagaag ccaactcttt gtttacgatg tagcgttcca attcacgacg
    59341 gatagtcgca ccatttggca accagaatgg caaaccttgt cccacttctt gtgaaatcat
    59401 aaagaggtca agctctttac caagtttacg gtggtcacgt tccttagctt cttcacgcat
    59461 ttgaaggtag tttttcaagt ctttcttgtc aaaccaagct gtaccgtaga tacgttgcat
    59521 catagcgttg tcgctgtttc cacgccagta cgcaccagct acatggagaa ggtggaagat
    59581 ttggatacga cctgttgatg gaacgtgagg tccacggcag aggtctacat attcaccctg
    59641 acgatagata gtcaaaccgc cttcgtcttc tgagtgttct tcaatcaatt ccaacttgta
    59701 agggtcattt ttgaagattt cacgtgcctc gtctttagtc acttcttcac gaatagatgg
    59761 gaagttttct ttgacgattt tttgcatttc ttcttcgata cgaggaaggt cttcgttaga
    59821 gatttgacca gctgtgttgt cagtatcgta gtagaaacca tcttcgatgg ctggaccaac
    59881 tcccaagtga atgtctggga aaagacgacg agctgcttgg gcgaacaagt gagctgctga
    59941 gtgacgcaag attggaaggg catcttcgtg atcaggtgtc acaatttcga tgcttccatc
    60001 ttcagtgata gcgcgagtag tgtcgatgag tttgccgttg aatttaccag ccaaggcttt
    60061 tttagctagg gaattgctga tagattgggc aatttcaaaa gttgttacgc cagattcgaa
    60121 ttcacgaaca gcgccatctg ggaaagtaat gttaatcatg atgttctcct tttttattat
    60181 ttcatagttt ctaagcattg attttttatc agcagactac ttccaagtcc taacgttcaa
    60241 ttgcttttct ttatcagaga ggaagttttc catttccgtc agaatgtcta tatccaaacg
    60301 ttgagaaagt tctaatagcc accagatatt ttctgaaagt ttttgttcca gtgtgtaggg
    60361 tgtttcatca tagtagcgtc cttgctttgt catcaccagt cgttggaaat ttccaatatc
    60421 attagataaa gccaagaggt cttcttctac cgtccacttg aaatcatgat gcttaacttc
    60481 cagttcgtga taagcttgtc ggattgccca actgcgctcc actaattctt gcaactccat
    60541 aattagtatc ctaataaaaa aatgcgacat cctcgaaagg acgtcgcaac gtggttccac
    60601 cttcatttat gtacctcaaa agagagggac acctctgatc ggctctaacg tggccaccgt
    60661 tttatgtttt cataaaaaac tcaagagtag tatcagttta gacttcctat gcgtttccag
    60721 caaccacgca ctctctagta gaaagggact aagtgacttg tctctatgga ttattatagc
    60781 atgattgtga gatttttcaa ggattttgtg aaagtttttt gtttttcata ttttgtagaa
    60841 tatgcttgat gctaatacca gaatccatgc ccaccagagc aactgtttca tagattagca
    60901 agtaaattag tataaactca ccaaaggtta tgatagtaaa gtaaaagagc agtccgttac
    60961 caactaacca tcaaagtgag aaacggaaac ggtagctata gagtaacgat acaatcaaga
    61021 ttaccagagg tgtaaagaag agaagattgt ttatatagtg taaaggggtc agaaacaact
    61081 agcaagaaca actcataaag tggctaataa aagaataata tgaccagata gtaggggaga
    61141 tgggaataga atctacgcat gataatcacc tcgttttaaa aaaacagaca acttagatct
    61201 cttgctatga ttattatagc atgtttaaaa caagaaagta aatttgttga caaagaagat
    61261 ttttcttttc actagaatca tagttagttt tcttggtaga aatattttga taataattaa
    61321 gcaagactat tgatattgat tattaagagt gtcacatttg ttgtaactaa aataattaca
    61381 acaatagagg tataaaaaat gaaactagca gttattgcag caaatggaca agcggggaaa
    61441 gcaattgttg aagaagcagt caaacgagga catgaagtaa cggctattgt tcgttctgaa
    61501 aacaaaagtc aagctgagtc tattattaaa aaagatttat ttgagttgac aaaagatgat
    61561 cttactggat ttgatgctgt tatttcagcg tttggtgctt atacaccaga tacgctaccg
    61621 ctccacagca aatcaatcga actatttaat cagcttcttg ctggaacaca gacacgtttt
    61681 ctagttgtag gggagcagaa agtctttata tagatgaaac aaaaacgaca cgacttttag
    61741 atacgtctga ttttcctgaa gaatttaagt cactagcaaa agctcaagcg gatgaattgg
    61801 atcttcttcg tacaaaaaat aatctcaact ggacttttgt cagtcctgct gtagatttta
    61861 ttcccgatgg tgaaaaaaca ggaaactaca ttctagcagg agaaattttt actactaatg
    61921 aaaaaggaat aagccagatt agttatgcag attatgctat tggattggta gatgaacttg
    61981 aaaaaggtca tcatataaaa gaacgtatct ctttacttga aaaataataa ctatgagagt
    62041 attaatgttt gacagaaaat ttaaatcttg gtaaaatagg gattgtcgta aagacaaata
    62101 acttcttctt ggttacaggc atgccaacct gtcactcgga tgaagccaaa taaaaaggag
    62161 aaacatcatg gcaatctcaa aagagaaaaa aaatgaaatc attgcacaat atgcacgtca
    62221 cgaaggtgat acaggttcag tagaggttca agttgctgtc cttacttggg aaatcaacca
    62281 ccttaacgaa cacatcaaac aacacaaaaa agaccacgct acttaccgtg gattgatgaa
    62341 aaaaatcggt cgccgtcgta acttgcttgc atacttgcgt aaaaacgacg ttaaccgtta
    62401 ccgtgagttg atcaactctc taggacttcg tcgctaattc aagatacaaa tgctgtcaaa
    62461 agcacaaagc aaaaatagga aaattgacga agaaacttca gtttctagga gattttatct
    62521 tttttgccaa gtgcttaggc cgtgttcaat tgagcatatc ttgataatga agctactcta
    62581 aattgggtag cttttttgcg ttgtcacctt acctcgatat actcaagtat aatctttggt
    62641 tacggttcct agcactgtaa ggtaaaataa accagctttt ctcccttcgg ggagattttt
    62701 tttgtttcac tgaaagtttc gtacgatctt cgcctcgtcg cctagtctat aaacgattta
    62761 tccagcaaga atcatgatgc taagggcgtc aaaaatccgt atgaaaatag ggaaatggca
    62821 cagtgttcga tgaacgcaag gagtttcatc tttttcacta ggattttagt ccgggctcaa
    62881 atcagctctc tgacttcaga gggctttttt attgaggttt tatcggtcac aattttggag
    62941 actacaaaaa cctcaaatgg tatcagctaa ttacaccata aaggtgcgca gttactcggc
    63001 ttttcaagcc gagtagctgt atgcaagccc cctagaagag cccactcttt acaaagtaaa
    63061 gtatagtatg ttatacttta catggaagta gtcactgaat tccagttaga aattactttg
    63121 taactacgtt ttgaggagga gtaaaatgct ttcctacgtt cgacattacc cactagcgat
    63181 agctaaatta atgtgtctgt gctctcctaa aatctgctga tttattactg actaatacag
    63241 gaggtttttt tatgggacag acaatcatat ctgctattgg tgtttatatt tccaccagta
    63301 tcgattattt aattatttta attattttat ttgcacaact atcacagaat aaacagaaat
    63361 ggcatattta tgcggggcaa tatctaggca caggcttact tgtaggggcg agtttagttg
    63421 ctgcttatgt cgttaatttc gtgcctgaag aatggatggt tggattgctt ggtttaatcc
    63481 ctatctattt agggattcgc tttgcaattc ttggagaaga tgcggaagaa gaagaggaag
    63541 aaattattga aagattggaa caaagcaagg caaatcaact gttttggaca gttacattgc
    63601 tgacaattgc gtctggcgga gataatttag gtatctatat accttatttt gcttcgttag
    63661 attggtcaca gaccctcgtg gccttgcttg tgtttgtaat cggcataatt atcttttgcg
    63721 agattagtcg ggtgttatcc tctattccgt taatattcga gacaattgaa aaatacgagc
    63781 gaatcattgt gccattagta ttcattctac ttggactata catcatgtat gaaaatggca
    63841 cgatagagac ttttctgatc gtgtagattt ttttgtttca ctaggatttt agcccgagct
    63901 caaatcagct ctctgatttt cagagggctt tttcattgag tataaatgga caatcttaaa
    63961 gttactctat tgtagagtgg cttttgattt gattaggaga ttcttataaa tatagtaaaa
    64021 tgaaacaaaa acaggacaaa tcgatcgtga cagtcaaatc gatttctaaa aatgttttaa
    64081 gaagtagagg tgtactattc tagtttcaat ttgatatata aatgaaaacc ttagctgttt
    64141 ggccaaggtt catttcttct atgcaagttc ttctcttttc ttatctgggt tccagatgaa
    64201 gcttgcgata aagctaaaga tgatggttag gatagcgagg ataatagcaa ggatgagggc
    64261 agggatgcgg ataaaccacc agagtggatt tggtttttta tcattgtgcc attgtttcgt
    64321 ttcttcgtcc agacgttgga attctgtttg aatacgattg gcgactgttt caatgccttc
    64381 atcattcatt ttcttgatat ctgagatatc gattggattt ccaaagttca tatcgacacg
    64441 ttcacggcta atcaagccct tcaaagtcat gggaccggtg taggtaaccg gcatgatacg
    64501 gaccttggcc attttggcaa tcagtgctgc gccccccttg acatcgtttg agtggcggct
    64561 accacttgga aacatgatga gagagcggtc actttttttg agaacgttga taggatattt
    64621 gatggctgag gcgctgggat tttcacggtc gatgggaaag gcgccacaca tacgaatcca
    64681 ccaaccaaag atacggttgg taaagagttc tttttttgcc ataaagatga actgttttgg
    64741 cttggtcgca aaggccatat aaacaggatc ccaccaggta cggtgaggcg caactaaaat
    64801 ataattttca tcttgattag gaattttatc agtattatga tagtgagcat tgccattgat
    64861 ggaccataag agcaatacaa ctaatccacg caaataagta taaaacatgc gatctccttc
    64921 gattgttttc ttgttattat tataccttat caaaggaggg ctggcaaact tttcccttga
    64981 ctagatgcat atttgggatg aaattagaat tctgttaaaa aaaatgatat aatagaattt
    65041 atggataaaa ataagattat gggattaacc caaagagaag tcaaggaaag acaggctgag
    65101 ggtttggtca atgactttac cgcatcagcc agtaccagca cttggcaaat cgttaaacga
    65161 aatgtcttta ccctttttaa cgctttgaac tttgccattg ctttggccct tgcctttgtg
    65221 caggcttgga gcaatctggt cttctttgct gttatctgct ttaacgcttt ttctgggatt
    65281 gtgaccgagc tacgagccaa acacatggtg gacaagctca atctcatgac caaggaaaag
    65341 gtcaaaacca tccgtgatgg tcaggaagtt gctcttaatc ctgaagaatt agtgctagga
    65401 gatgtcattc gtttgtctgc aggagagcag attcctagtg atgccttggt tttggaaggc
    65461 tttgcggaag tcaatgaagc catgttaacg ggagaaagtg atttggtgca aaaggaagtt
    65521 gacggcttac ttttgtcagg aagtttccta gccagtgggt cagttttatc tcaagttcac
    65581 catgtcggtg cagacaacta tgctgccaaa ctcatgcttg aggctaagac cgttaaaccc
    65641 atcaactccc gtatcatgaa atcgctggac aagttggctg gttttactgg gaagattatc
    65701 attccctttg gtctggctct cttgctggaa gccttgcttt taaaaggcct gcctctcaag
    65761 tcatccgttg taaactcgtc gacagctctt ttgggaatgt tgcctaaggg aattgccctt
    65821 ttgaccatta cttcgctctt gactgcagtg attaagttgg gcttgaaaaa ggtcttggtg
    65881 caggagatgt actctgttga gaccttggcg cgcgtggata tgctctgtct ggacaagacg
    65941 ggcaccatca cccaaggaaa gatgcaggtg gaggctgttc ttccactgac ggaaacttac
    66001 ggtgaagagg ctattgccag catcttgact agctacatgg cccatagtga ggataagaat
    66061 ccaactgccc aagccattcg ccagcgtttt gtgggagatg ttgcttatcc tatgatttcc
    66121 aatcttccct tctcgagcga ccgcaagtgg ggggctatgg agttagaagg cttggggaca
    66181 gttttcttag gggcacctga gatgttgctg gattctgaag tcccagaagc cagggaggcc
    66241 ttggagagag gatcacgtgt cttggtctta gctctcagtc aggagaaatt agaccatcac
    66301 aaaccacaga aaccatctga tattcaggct ctagccttgc tggaaatctt ggatcctatt
    66361 cgagagggag cggcagagac gctgaactat ctccgttctc aggaagtggg gctcaagatt
    66421 atctctggtg acaatccagt tacggtatcc agcattgccc agaaggctgg ttttgcggac
    66481 tatcacagct atgtcgattg ttcaaaaatc acggatgagg aattgattgc tctggcggag
    66541 gagacagcga ttttcggacg tgtttcccct catcaaaaga aactcattat ccaaacgctg
    66601 aaaaaagcgg gtcatacaac agctatgact ggggatggag ttaatgatat cctggctctt
    66661 cgtgaggcgg attgttctat cgtaatggcg gagggagacc cggcaacccg tcagattgcc
    66721 aacctggttc tcttgaactc agactttaat gatgttcctg agattctttt tgaaggtcgt
    66781 cgtgtggtca ataacattgc ccacatcgct ccgattttct tgataaagac catctattcc
    66841 ttcctgttag cagtcatctg tattgccagt gctttactag gtcggtcaga gtggattttg
    66901 attttcccct tcattccgat ccagattacc atgattgacc agtttgtgga aggtttccca
    66961 ccatttgttc tgacttttga gcgaaatatc aaacctgttg agccaaattt cctcagaaaa
    67021 tccatgcttc gtgccctacc aagtgccctc atggtcgtgt ttagcgttct ttttgtgaaa
    67081 atctttggaa cgagtcaagg ttggtctgag ttagaaatct caactctcct ctattatctc
    67141 ttggggtcaa ttggtttctt atccgtattt agagcctgca tgccattcac tctatggcga
    67201 gtcctcttga ttgtctggtc agtaggaggc ttcctagcca cagctctctt cccaagaatc
    67261 caaaaactgc ttgaaatttc aaccttgaca gaacaaacgt tgcctgttta tggtgtcatg
    67321 atgttggtct ttacagtgat tttcatcctg actagtcgct atcaagctag aaaataaaga
    67381 aagactgcaa tctgtggatt gcagtttttt atacgatgga tctatcgtag atctgatgtg
    67441 caaggcctac gtgtctatta tctatcggtg aacccaagag tgattctcaa gcctgcttgg
    67501 attgaggtaa tagattcaaa tatctgtagt tagactattt gaagtttgat gtaagaaaga
    67561 gaaagcgaca gattgaagta attttaactc tcttctattg ctagaacaaa tggtcggata
    67621 ggttggtagt ttgaaaatga agatgcaatc tattgttaaa tggaacatag tgttatttat
    67681 tagaaaatcg tttggtttat ttcttatcaa atacgaaaag caacttaaat atttcaacta
    67741 aaatagatgt tatgaagaaa aggtaaaatg attttggtat agtgaggttc tgttctattt
    67801 gatatcatat ttttgataaa aacaaaaatg tccattgcaa aggacaaaat gcgaagtata
    67861 ttattttttg aaagcgatat aatggaatca taaaggaggt gtatcgtgtc tagaaaacaa
    67921 gaacaaatgg aaacgttgtt gctccttttg cgagatagta aggattatat atctgctaaa
    67981 gtattgggag aaaaattaaa ttgctctgat aaaacggttt atcgccttgt caaggtaatc
    68041 aacaaagatt gtccggtaga agcattcatt ttatctgaaa aaggcagagg tttcaaatta
    68101 aatccaagaa gttccctcgt ggacgttgat gggaatttta cagaggcttt tgatcctgaa
    68161 gtaaggcgtg aaaaattact agaacgtctc ttgttgactg ctcctaagcc acattctatt
    68221 tatgatttag gagaggaatt ctacgtaagc gagtcagtag tactaaaaga tcgtcagata
    68281 ttacaagaga gtctagcaat ttatgggtta gatttaaaaa tgagacaacg aaagcttttt
    68341 attgatgggg atgaggctca aattcgttca gccattctaa atctactgcc aatgtttaat
    68401 cagttggatt tagagcaaat tacacagaat aaggttcagc ctcttgacgg agaacttgct
    68461 cacttttgtt tgggattact gattacactt gagagagaat tgggggtaaa cattccctat
    68521 ccatataata taaatatttt ctctcacctg tatattttta tcagtaggaa tcgtcgtagt
    68581 actagtattc atgttgtagc accttcaaaa cctactattg ttgatgagaa aatttacagt
    68641 gtctgtcaaa aaattattca agaaattgaa caatatttta agatgaaggt tgatgcagtt
    68701 gagattgact atcttaatta ctttgactaa aatacagaaa tacgctagac cctttaaaaa
    68761 tctagcgtta tcgacatgcc gtcttttgta acaataattt cttttatgat atttttgaca
    68821 atttttgaag catcttcgta gcttaatttt tcaacatcga agtcctttag tagccgtgtt
    68881 agctttctct ttcggatgct cagaacattc gatttttgat tttcgagctg ttcttccagg
    68941 aattgccttt ctgttttgat tttatcattt ttctcgtcca actctttccg agtgatgatt
    69001 tcgtccaagt acaattctgt taattttgag acttgattat ttatccgttc gagttgtttc
    69061 tttatctcct cgaccttgat agtctcttct ttcttagcga gtgtctcatt tttatatttt
    69121 ggatcaaatt taattctttc aagttccttg attacacccc tttcaagttc ctctttagag
    69181 taccaccctg attcgcatct tttttctaaa tctttgctgt gtcggttcct gcattggtat
    69241 ttatgatgag agattccatt cttgtctttt cttgtatatc tcagaccaag tgaagcacca
    69301 caatatccgc atttcattaa tccagaaagc atatactttg ccctgaacgg ccttggattg
    69361 ttatattttt cataggctga aatctgcctt ctttcgactt caagctggac taagtcaaac
    69421 aattcttgag tgataattgg ttcatgctgc ccctcgtata ccttatcttt gtactttact
    69481 tttcccaaat aggtttcatt tttcagcaag tatttcgtga ttgtttcgcc ccaaggtctt
    69541 tttcttccaa cgtgaccttc agcatttaag tctctgatga tcttgactac tggcttaccg
    69601 ttcaagtatt ccgtgaaaat acggttgaca atgagcgctt gggtcggatt cactgataag
    69661 acgccagttt cttttgagta atcatagccg aatgctattg tcgtccatga catggatttt
    69721 ccattctttg cccgtccttc ttttcctaac atcatacgct ctttaatctg ctcacgctcc
    69781 agctgagcga atactgatag cataccgatt gaagccttgc cgaaaggcgt agaagtgtca
    69841 aagttttctt gcaagctgat aaatgccaca tcgtttttag caaacacatc ttcaatcaga
    69901 aacagagtat ctttctggct acgactgagg cggtctagct tgtagactag cactatatcg
    69961 actttcttgc gcttcacgtc tgagattaaa cgctccaatt caggtctttg agtgttagca
    70021 cctgagaaac caccatcaac gtagacatcg tagattttcc agtctttgat tttacagtag
    70081 gcttcaagct tgtctttctg ctcatcgata gagtaaccct cttccacctg cgaagtagtg
    70141 gacaccctga cgtagattgc gactttattc gttgttttca ttgaatttgt accccttttt
    70201 tgataaaata ggtacaagaa aacgtctcaa aaggtaatat cttttgaaaa gtttttcttg
    70261 ccactagcct cacgctcgga gtcgccaaac tttgagagcg tgaggctttt tttgtttgca
    70321 attatttcca ttttggaaac agttggtttt attctttcga taagtgttgt tgaagaatta
    70381 aggccacgtt ggctttctct tcctctgtca taggaggttc gtttggatcg tctaccgaaa
    70441 actcgatagc atgccattta tcatttactc taatccactc tcttcgtctg tggcatttgc
    70501 aatctaggtt gtgtttaatc acttccatcg gtctactttc gttactcatg ttatttctcc
    70561 ctatacaaat ccacgacttc gccgataatt cggaagtcgg tgtctggtgt aattggcata
    70621 tctttatatt cagggtttag gctatgtagg taagcctggt cttcatcaat aacaagctgc
    70681 ttgatataag catcgccgtt gtagttgaat actccgataa ctccgtcatt caaatctaca
    70741 cttgtctgaa tgaataccag gtcaccatcg tggtagtcag gctccatgga gtcacctttg
    70801 atggggatga caaagtcagc atcaacatct actggtaact caatccgttc cactcgtaca
    70861 tcattcaaat actggcctgt acctgcggaa gctgggtggt cgtagtagtc gtaactgtag
    70921 agccgaatag cttctgatac ttcgtttatc ttcgtttctt cttcgttttt ttgctctttc
    70981 agttgcctct ttgcataatt caggactttg ccctgtctag gtggttctag ttcgtcgtag
    71041 atggtttgaa tttggggagt attagaagaa gagtcattga ccatgaaatt attagttata
    71101 aatctaggat ctaatacaga tttaggaact ccaaaaaaat ctgcaatttt ttgaacatta
    71161 ccagggattg gcaaagaagt tccttttaca taccctgtca atgtactagg cggtattcct
    71221 gttgctcgag acagctcagc ttgtttacaa tttctatcag ataaaattga gttaagattt
    71281 gcagaaaaga ctttcatatc ctctttatct tgaggagtta atttccctcg tcctcttgcc
    71341 atatttttac ctcctatctt ctttactata taataccgtt tattttcgat tttgtaaata
    71401 aaaaattcga aaaaattacg aaaaaattcg aaaaatcatt gacatacgat ttaaatcgta
    71461 gtataatata atcaagctta aggaaataac aaaaacaaac cggagggaaa caccatgaac
    71521 acattaaacg agaaagcaat caacatcttt aaagcagtag ctaaggaaac tttaatccaa
    71581 ggcacttacg aggaaaactt cctttacagc cagcttgaag cattctgtac taactgccgt
    71641 caattcgctt ttggatggac agagttagca gaggagattg aacgccaaga gcgttacctt
    71701 ctcgattctg gtttcactca agaggaaatc gatgacattc gttttgatgc agcatttgca
    71761 ggaatgcttg ataaattaaa tgtagcctga ttggtatcac caaggttcga atccttggca
    71821 ggttgttgct ccaagagcaa aataaaaaag acaaggaggt gggaagatga acgaactaga
    71881 aagaacagcc ctcaacgaga tattgaggac tgtgacatat attgctgaga aagtggatga
    71941 gattgactct aagatttctc aatcagaaga agatgtaaaa atcaacgctt catctgcatc
    72001 gtaatcagca gcaataaatt gagtcgccga aagaatgaac ttctttaaat catcgatatc
    72061 tttaccatcg tgtctgcgga cataatgagt ctcatcattg cctatccagg caacagattt
    72121 tgccaagact tgaatttttg gaaaatcgtt taagtatgta gaaattactt gcccaagcat
    72181 aattgatttg atttttcctt catcagatgg atttttggaa attgcgtagt cctttatcag
    72241 gaattcggct gctttgcgat agccgacacc tgctatttgg tctaatgcct ctctttctgc
    72301 aattgttgct tgagaataga tttcaacaaa aacgggagaa actttttcta tgttttcagg
    72361 gagttttacc ttgattggag ggcggtagct gtattcagca attatacaag gtttagatgt
    72421 agatgtgaaa atatactcaa cagcaaagta ttttttacaa gttgagcgtg agcaacgaaa
    72481 agtaacaaca aagcgagcat ctccactaga gtaactgtcc tcactgtctg aaacgtatat
    72541 catttcaggc gagatattct ttccgcaatg tgggcaatat tcaggatatt caaattttac
    72601 tgtctggcga ctcgcgccag agaatgaaac gatagtggtt ttcatagctt ttttctccaa
    72661 tcatttttat tttgattata ccacatttga aaggtagtta gaattggaag ataaaattat
    72721 cgaacttgct gactacttca tcagcgaatc tacaacgtac agagaagcta aaatagtgtg
    72781 tgagaagcta ttgaaacaag tcagccacga gattgaactc agggcaatgg aaagtaggac
    72841 gagggtatga aagaaaaact aaacgaattt ctaaaattca gaagccagtt tacaaaacga
    72901 gaatggattg aaattaacca agttgtcgaa gctcgtttaa atgaaaaagc cgaccagttg
    72961 aaactggacg actcagatgt agaaatcatt tctaaaagac taggacggtc tatctaaaga
    73021 aagggtcaaa caaatggcgt ctaacagaac tatatcagta aatacatcag agaatgatgt
    73081 attgttgacg gcaagaaaaa accaccctgc tgtattcgtc gatggaatgt ttctcgacgg
    73141 agttgagcga gtggaattta ccaatcatta tctggagaag tgtgaagttg ttttaacgtt
    73201 taacgataga gttgaaacca atcccttccc tctaaacgat attactttat tagaaaagtt
    73261 atttggtcag agttcgaacg gtcaatcttt acgggatatt gtcgtgcaaa ctcttgaaga
    73321 tgctgattag catctaaacc atcaaaaaaa gaaacatgaa cactaaaact ttcttttccg
    73381 tttttcttgg ttctatcaaa ttctttgcca aggacaatta gagaagcttc taattgataa
    73441 tcagtcataa catcacctcc tttctagctt tattatagca gaattgcgag gaacaaatag
    73501 aaaaataagg aggtaggaac gtgccgaaaa tgacattgag agcaataaga acaaattata
    73561 acttatctgc aaaagaagtt gccgataaac ttaacattca tcaacaaaca ctgttgaagt
    73621 atgagcatga tagttcaaaa attccaatgg atcttttaga taaacttgct cgactataca
    73681 atgttgaaaa ggattttatt tttttaggca aaaaatacga attaaatcat aatctaggag
    73741 aggtgtgaat gaacgagcga gagttataga aaggggatta aatatgaggt atgcagtata
    73801 taatcaggaa tactcatggg aattacacat ctttgaataa tgcttatgct caagacaaac
    73861 gtttaaaggc aacaacgata ggtatcctta cagtaatctt gatgaataag tctgattggg
    73921 ttgtgtatcc tgacgagatt gcacgacgtc taggaataag caggcgcacc gtagatgagc
    73981 actttaagct tttagagaaa gcaggctatc tcagagtata tcgcttaggg ttaggcagag
    74041 gtaaaggcgt aacggtatat agattttttt cagatatgcc tatttcagat gattactttg
    74101 agtatctaaa aactaatctt gagaaagagt tatccacaga taacggagtt taaaaataca
    74161 gttggaaaat attgccatgt gtaaaattgc catgtgtaaa attgccatgt gtaaaattgc
    74221 catgtgtaaa attgccctct aataagtact aactatacaa caagtactaa ctatacaata
    74281 atctaagcct aacggcacta acttagtaat aactactaac ttacaacaaa ctaatacttc
    74341 tctaaaaaat aaaagagaga aatttcaatt ttaggacttt gaaaaatagg aaaggagaaa
    74401 aaatgagacc aagaaaatat ccgtatagtg ggaaaaaaga gtccaccttt gtaaaggccg
    74461 accctgagtt agttgaaaaa cttttaagaa acactagttt tcttgagtgt ttacaaaaaa
    74521 agcctatcaa ttttcagata gactcagaag aatttaagcg tcttagctat gaagccattc
    74581 atgatacttc tcaagtaact caatagtagt tattacagaa gtcaaaccac tgaccttccc
    74641 cagttgcaat ccgtctgtat ggtcaatctg tttagtagct tcattagctt tagcagagat
    74701 agcttgcata tcttcagctg ttaaagattc tcgaaaatct ttaaaggatt tcataaaaac
    74761 tcctcctttc tattggaatt ttgactaaaa cggtgagagg tcctagtcga gattattata
    74821 gcaatttagg aggatattac atcggtcttg aggctgattt ttggaggcaa tattggaaga
    74881 taaaatcata gaacttgctg actacttcat cagcgaatct acaacgtaca gagaagctaa
    74941 aatagcgtgt gagaagctat tgaaacaagt cagccatgag atagaactca gggcaatgga
    75001 aagtaagaca gtctagaaga caacaaaaag cacctgacgg caatcaggcg catactaaaa
    75061 aactttacaa gaggattata acatgaatat gaacttaaat acaaatgaaa ttttaacaac
    75121 tactgaatat gatatgtttc gcaaaattag taatagaaaa ataactgaaa atcctaaatt
    75181 ggaagaggag ctactttctg agggacaacg tcagccgatt ttggtaaatg aaaaaatgga
    75241 agttatcgac gggcaacatc gtctttatta cttgagaaaa catagaaaac cagtgcgcta
    75301 cataattgat ccgaccgcta atttcaagac agtaatttcg atgaatacat cagctgtcaa
    75361 ctgggcatta caagattatg tgtattcgtt cgctttagag ggagatcctg aatttgttaa
    75421 attagctaaa tttttagacg agaacgaatt gcttagtgac aagatggtaa tcgtagctgg
    75481 ttcaggaaga cgtgatggta cggcagcaca cgtagtcaaa aaattaaaaa aaggcgatta
    75541 tgtattttca aacgaaaaac agttaagaga attttgtaag ttctacgaac gcgttttaaa
    75601 cgaaacaaaa ctgcctaaca aaccattttt acaatctgtt ttatggactt tgtatacaac
    75661 atcagttttt gatgaaaaca gaatgttgac acaattgaag aaatcagatt tgacatcaga
    75721 agatatcgaa ggatttgcaa agaaaaaatt gctattaact tttttagagc tatacaacgg
    75781 aagatggagt gacgatcatc cttctttaat tcaatacttt atcaacagaa aagggtcgtt
    75841 aacaattcct agtttgccta aacaagatga agataattaa aaaagtagga agataaaatg
    75901 aaagtcacag tatatgttta cggccgaaaa ttagaaccag atgaaccaat tatcatccca
    75961 gaaaatcatc gtttttatga catttggaac ggaattgtaa atgaaatgct cgacaacgag
    76021 gaggatgtag cttaatgaaa ctacttacta aattaaaact cagactcgaa ggagttctta
    76081 aatcagtcaa ccttgactgg agagaggtag cagtcgaact tatgaacgac ctatttgagg
    76141 agcgcaagcg tcgctttgct ttcgagcaag aaaactatga cttgaagcaa caattggcaa
    76201 tctacaaaga aaaagaacaa ggagaacaat atgtttaaag cactaaaaac aatcaaaaaa
    76261 atcaaacagc ttcagaaaga aatgcacgac gcaagcgtag cattcctact tatgcaagac
    76321 ctcggtttgg ttcctgatag cgaaaaagga agaaccatag ctaaatcgtt ttatgatgta
    76381 agccacatgc tcaaggacgt cctgggcggc aagtcggtag atgaagccat gaaacgtcta
    76441 aatagcgaag tgaaaattga agatgtggag caggaagatg actagaattg aacttgaaaa
    76501 ccgtgtatgg cttttggcta atcatgaaga aaaaaacgaa ttgctggatc ttgggctaac
    76561 atccaaggct agatatgtga agcgagttct ggaactagga aaggtgtatg ctcatgtttg
    76621 attacgacag agacataatg caaccgcctg aagaacgaga agaacgtgac ccagctgatt
    76681 ggattttcag cgctggtcaa tggatctatg taggagattg ttagcctatg aatagagagc
    76741 atttagagcg tgaaaattgg aatttgaaga agacgaaagg tagaaagaaa tgaaaaaacg
    76801 attatattac aaaaaatgga aacaagaact tagagaggca atgagagaag aaattgatgg
    76861 cgattatcta accgagaaaa tggttagaaa aatgagtatt agcgatatgt cacactattt
    76921 gaaccaatta gcattagaag aagctggata ctgtgggaca atgtttaatt actaaaagaa
    76981 aaaggagaga aaatgactaa taatcaatta gcaacacaga caaaacgtaa catcactact
    77041 gacccaagtt tattgaccgg ggcagacatc aaaaagtatt ttgacccaca aaacctactg
    77101 actgaaaaac aagtaggtca ggcgctagcc ttgtgtaaag gtcgcaatct taacccattt
    77161 gctaacgagg tctacattgt agcttacaca aaccgtaatg ggggtaaaga gtttagcttg
    77221 attgtctcta aagaggcttt cttgaaacgt gccgcccaat gtaaagacta tgaaggcttt
    77281 gaggctggag tagtggtagt agacagtgag ggtgttatgc acgaacgcaa aggggcaatc
    77341 atgctcccag aagatacact gataggcgga tgggctagag tgcaccgcaa aaatttcaag
    77401 gtacctgtgg aaattgttgt cagtcgtgag gaatatgaca agaaacaaag tacatggaac
    77461 accatgccag ctaccatgat caggaaagtg gctctagtaa atgctcttag agaggctttc
    77521 cctgaggact tggggaacat gtacacagag gacgacggtg gagagacatt tgaccgtatc
    77581 aaagacgtca cacctcaaga gagccgtgag gatgtcgtag cacgcaagat ggctgaaatt
    77641 gagcaattca acaaagagca agaggcaaat catgcagatc ccgaacctgc tcaaactgag
    77701 gaaacaatcc agggcgaatt gctagacggt gaacttgaat attaggagga caacatgcaa
    77761 gaattacagg ttattgatga taagaaaatc aataaaatct atgagatgat cacaacggat
    77821 gaacttacta gagagtcttt tgaaaaagac ctcatagagg ctactgagaa gtacaaggac
    77881 tatattccta cagctggaac tctcaaagac gacaaggcaa agcgggctga atttaacaag
    77941 ttaattgagt ctaaaaatcg tatccgtatt gacactaaaa acttactatc agagacagct
    78001 aacacatggg atagttatgc taagtcaatt attgacccat ttgcaaccgt agttagtgaa
    78061 tttgacaaag gtatcaagga aatcgaagaa catcaaagac aactaaaaat agatacggtt
    78121 aagagttacc tagccaacaa atcggctgag tacatgctgg atcctcgtct ctttgatgaa
    78181 aaggcccttg agtatgtcaa agctagcgat tttatggcag atggcgtgac gcttaaaaaa
    78241 gccactatga agtcacttga tgacatggtc acatttgaat ttcagaaaca acaagaattt
    78301 gaaaaagcca agtcagctat ttcagggtta tgtgctgagt acggcatgac tgactcacct
    78361 tacattagac agctgaaaga cttgactctt gctgaagtct ttcaacaaat caaagctgat
    78421 tatgagtttg aaaaggaaga actcagacag gctccaaaat caacggaaac cccaaatttt
    78481 gacccagaaa cgggcaaaat cttggacggt ggacaaatcc tccaaaatga gcctaacgct
    78541 cttagagggg ctgaaaatga cctaaaacga tatgcccaaa aaatgacttt agaggtgtat
    78601 tttgtagaca cagccgaaaa agaccgtttc aaggctggtc taagtcaact cggatttgat
    78661 tttaaaaaga actatcaagt cagcggttat caacgtatcg agccattaac tcaggctgaa
    78721 ctaaatgaac aatgtgggtg gtaagtatga cagaaattga aaaaatttca gaagaattgg
    78781 ctgaatatgg ggtgcctgat gagttaatag gaaaaataga ggacctatta gcgactctgt
    78841 atggcgaaaa aaggaaattg gagatagaaa aatcttggat atttctccag agtcaatggg
    78901 gaggtaacca tggacatcag aaaaatatct gacagcgtag ccatctactc ggacggcaag
    78961 aaattgcagg ttatccacaa cctaggggat gagtttatcc tagattttaa ggtgggagag
    79021 gatagcgtct ggaacctcaa tggccaagtc gtagaaatta ttgacatgat tgagcctgtc
    79081 tttaaagttt tcagcttttg ctcaaaatct ggagagggta tgcaacgctt aaaacatgct
    79141 atcgtccact ttgaaaaatt tgagcagtac atcagagata atcaggaaga cctgatgatc
    79201 tggtggcaca atccaggagg ggaatatgat taaaaccgta tttttttcat gtgattatcc
    79261 acatcatgag gtgattgacg accaaataaa tagctggctt gccgaaaatc caggcattaa
    79321 gttgattgac atcaaatttc aatcaaatgt gtctgctgtc gctgacagtg gagtcagtgc
    79381 tgaatattgg catacatccg cattgattat ttacaaagtt ccctcagaga acaatataag
    79441 cagtattaat tcaaatggtt taggtttcat aatcagctgt gagaaatgtg gtagcttatc
    79501 aataatcaag ggaaaagatg taggtcaaaa tgtatgttat gaatgcaaag gagagaaata
    79561 atgaatgatt ttatcaaaga gattgggatg gctatcctat ggatgttttt agggtatctc
    79621 ttgggagagc gtagcactag agggggacaa atcagatgat caataacgtc acactggttg
    79681 ggaggcttgt agcgcctcct gatctacgaa aaacgcctaa taatgtatct agtttacagg
    79741 gcacgcttgc agtcaatcgc aatttcaaaa acgaaaatgg agagcgtgag gctgatttta
    79801 tcaattttca agcttggaga ggtacagctg acatcattgc tcagtattgc agcaagggct
    79861 cacttattgg cctcacaggg cgcttacaag ttaggtctta cgagaaagac ggtcagcgtc
    79921 gatatgtgac tgaagtaatc gctgagagtg tagctctgct agagagtcgc aacagtcagc
    79981 acggacaagg caacagtttc caaaatggga atagctcacc ttttaccgat cctaacccct
    80041 ttgacctccc aaatgacggt ttgccgtttt aggaggtata tatgtcaaaa attaaaattc
    80101 ttgacgcttg ctgtggcagt cgtatgtttt ggtttgataa aaacgaaagt cacacaattt
    80161 ttatggacat taggcaagaa acatttgaga tacatgacaa aaaggtcaat gtagaccctg
    80221 atattatcgg tgattttcgt gacatgcctt ttgaagacaa cacatttaat ctagttgtgt
    80281 ttgatccacc acatctaaaa tgggctggac ctaattcgat aatgaaagct cagtatggac
    80341 agctggacaa agttacctgg tcggaagatt tggccaaggg ttttgaagaa tgtctgagag
    80401 ttctaaaagt tggcggcaca ctagtcttta aatggtctga ccgtcagata aatgtaaaga
    80461 aattactaga ggtgatacca ttcaagccct tatttggtca gcaaagaggc accacacact
    80521 ggctaacgtt tgtaaagttt gaggaggaca agaatggagt ggacggattg ggtggattgg
    80581 aaacctgaaa ccaaaacgga cattaaaacc aaaattgaaa atgacgggta cacttttcca
    80641 cactatgaca agaaaaacaa cggcgtcaag tacgtcatct ctacactgga catcaaacga
    80701 gactgtctaa gacttggagt accgtttgaa gatgtgtacc ctttgcaaac gacacttttt
    80761 taacaggaga aagaacatgg caagtaaaat caatgcgaca gaacgtattg ctatcatcat
    80821 tgagaaacaa aaaatagagg tcgttacgac tctaaactat gatatgagca ttagctttga
    80881 taacaaagac acggctccta cactagatga caatggtgac ctttttgaac cggtctacaa
    80941 gtgcaaagtt aaggcaattc ccaaaaatga tgtatttttc acctcattaa cacgagtcaa
    81001 gagcaacatc aagacgctac aagaggttaa aaaattcttt gagttcgtaa acgaaaacag
    81061 agaaaatctc tttgagatgg caggatttaa gggggctctt gaatgaaatt gaccctaaac
    81121 attgagccta aacctcaatc acggccaagg tttgcaagac gtgggagttt taccacaact
    81181 tacgaagaca aggatatgaa aacatggcgc aatcattgcc agctgctcat tgctaatcag
    81241 tacatgggtc agcctatcct tgagggagct ttgagggcac ggcttagatt ttatatcaaa
    81301 cctcctcagt acatttccaa ggtcaagaag aaccagcagg ccctcctaga tgaaatcatc
    81361 ccagtaggca aaaagcctga cattgacaac tacgaaaaag ccctatatga cagtatgtca
    81421 gggatcgtat tccaagacga cggtcagata gctctgcatg atgtaggcaa gttctacagt
    81481 ctaaatccac ggatagaggt tgagattgag gtcatgaaat ccctgagtat ttgaagaaat
    81541 gaggagcaga tggctgacta cgcattatat caaggtgatg tgtttgttac gcttggaaca
    81601 ttagcgcaga tcagtagcga gacaggaatt actgaaagga tgttaaagta ttacacttac
    81661 acatcacacc aaagacgaca cccaaacggt agggccgtta ttaaaattga ggaggaagat
    81721 aatgagaatt aagacggaaa gcggaggagt tggaagatga tggaagagtt aaagcaaaaa
    81781 gttaatgcag tatacaactg gacggtagaa gacgggaagc cgcaacctcc ccagcaagat
    81841 ttaccacaag tggtgaaaga ccgggcggac tatttttggg aaatggcaga agatggtatg
    81901 acgtttatgg gagcgatgga atgcatcttt gctgatgaaa agcctacaga ctatgatttg
    81961 ggagctacta aggattggtt gccaaaatct aaggagtttg atgattgggt tggctattcg
    82021 ccaagcatgg ctcaggtagt tattgcagtt tatttgattt atggaggaag cgaagatgaa
    82081 taagcaggaa ttgattgatt attgtaacgt tttaaaagaa agtaaaagta gatttatcaa
    82141 ttgtattgat gtagacagaa tcatagatac aatcaaacaa ctagacgaac cagaaaaagt
    82201 caaagttccg cggtttgtgg ctgaatggat tgaggaagct agaaaagctt gtaaagacgt
    82261 ggtagaatta ttcgaatttg atttcacgaa cgatgaagtt agaaaatggt ttatgcaaga
    82321 aagaccattt gatttagtag ctagagcatg gcttgatggc tacgaggtcg aggaagagaa
    82381 gcggtatttg gtgactttaa aaaataggca gcctttggtc aaatcgcaat cagggagtac
    82441 tctttatttt agtcaagata taacagctag gaattataaa ggtactcaaa aagaactaga
    82501 agacgcaaac ttcggctggg tgtttgattg tgaaggaatt gagattgagg gggtggagtg
    82561 atgtcatgta gtgaaaattt aaaaaaagaa aaagaattga ctgctgctat ttcaaatttc
    82621 aagatagaag tcttacaaaa tgatgataaa ttgagcagtc tatcattaag caacatcaaa
    82681 aggcaagcaa gggatctata tgaatgctta gtatggttgc agtataatgc ggaggaatca
    82741 ggtagatgag ttatgatttg gaaatattag taaaaataga gagtggagat tatatttgta
    82801 tcgctgaacc taaatatagt tctccgacct acaatcttgg aagaatgttt agagttgcta
    82861 tgaactggga ttttgatcaa gacactacgt acaacatcgc tgatgtttta gataacattc
    82921 aacgcggtat ctctgaacta gaacggtacc ctgaaaagta tgtgcagtat gaacctgaaa
    82981 atagatgggg aacagttagc gttgcattgg aggttttaaa gtcactgaaa gagtgtattt
    83041 tagaacaaga tattgatacg aaatatttat atatgaggtg gtaatatgaa acgattcata
    83101 gctatctgga ttctgctatc tgctggattg aatatctggc agagtatcta cattaaaaag
    83161 ttagaagaaa agcgtccgat tgtcgtctat aaagctgata acgcaggcgc tgagatattc
    83221 ggtaaagtcg tcgagaaagg acggcatggc aagctatata cgcttaccat tcgtgactac
    83281 ggggtgttcg tggttacgaa ggacgtgtac gataaagtga aagttgggga tgaggtgtta
    83341 ctatgacaga aactattaaa ctaccagact attatgagcc tgattggaaa aatgcaaggt
    83401 acgggtcgtt ggaagagctt aaagaattgt tgctctttaa gcgtattgtg aaatgggata
    83461 aggacttttt gctgcttgaa gacggcacaa aggtcactat tgaaatgtct gaaagtgatt
    83521 gctgtgcctc agcaggtggg gagttccaag atgtatcact tgacgctgtg attactaata
    83581 ttgaaattgg agaactggaa gaaatccccg accattgggg aactggttat aaaaacaaag
    83641 taactatctt ccataatcag aaccctgtag ctattgccaa ttgtgaagca gagcataacg
    83701 gctattatta cagcgtatgc tctttagtga ttggtgatat tcattttcca gttgttaatg
    83761 cttaggagga tttaacatga caccaagata tagagcgtgg ataaaaacag aaaaacgtat
    83821 gtttttttca gatgacattc ttgctattga ctacgaaaac aaagaaatag tgacacaaca
    83881 agtttatttt gagaatggtt taccagacga tagagatatc tattgttatg attttgacga
    83941 aatcgaactc atgcaatcaa caggactcaa agacaagaac ggcaaggaaa tctttgaagg
    84001 cgatattgta cgaactacta gatttttggg tagagctgac gaaattggcg gtttctatga
    84061 gtatgacaag gaatttatag ggattgttaa gcagcttgag ggttcttggg taattgatac
    84121 gggcagtgac gcagtatgtt tatggactga aattgaagaa aatgaaatca tcggcaacat
    84181 ctatgaaaat aaggagtttg gaggacgcaa atgagacctt gtaaatatcc atattcagga
    84241 agaagaaaaa aacaagaaac gccgtcgcca atattttctg cacgaccaat ttttgacgaa
    84301 gttccaattg tagaagaagt taaggttgag ttcggagttg aagctagtat ggggcgcata
    84361 tatccagaaa cgttaataca tttagatatt tctggatacg gaaatagagt gcattcagta
    84421 catcgcttcc ccggtatttt actgagtgtt ggtgagtcaa tccaactaaa gatgcttttc
    84481 tataaaagac ttagaaattt tactacagat cgtttcttga cgtttagaga atctgattgg
    84541 aagttcttta tccgggacct ggtcaacgaa tttaagcatt aaaaaaagcc aagacactct
    84601 ctgcctcagc taatagttct cgcaaagact attatatcac aaaggagaca gagagtgaac
    84661 aaggctaaag agctcttgaa agagttgcag gatctggaca tggacatcca aagccgtata
    84721 gacgaaatta acgagcttga ggcaggtttg ctctcaagcc ctaaatggtc cgaggttaaa
    84781 gtccaaggtg gacagactag aaaagttgat gatgtctata ctcagttggt agtgatgaaa
    84841 gaggctatag agcaggatac taaagaggtc attaacagaa aacttgaatt aggtagaatg
    84901 atcaataggc ttaaaaatcc aaagtacagg gcagtattaa gaatgactta catcaacaaa
    84961 ggcaccgctg atagcgtttg ttatgatttg aatatgagtc gtacaaccta ctacaggtta
    85021 aaaaatgagg cggtcttagc tttggaagaa gttatctaac ctcatagtga gcttatggga
    85081 ctttttggaa cagcacggtt ctaaaaatct gttagaatgg tagtatcaag aattgaaaag
    85141 agaggtctca gaattggtag atggttacct gtaatgtcag ggggctgtaa tggccttgga
    85201 ggttcaagtc ctcccctctc ctttgagtgt ttgtgtccca gaatgagtta aatcttctgg
    85261 gtggggattc acatatcact cattaactcc tatcactcat taacttaaaa atggttgcgg
    85321 aagcgactgg acctcgcatg attgcgtagc taattatatt ccggataagt tataagctag
    85381 agggtttgat tccctcagag gttttaaaga ctacaaaaaa taaaaaagaa gtcaaaattt
    85441 aatacgcacg caaggttgta gtcgccttgc aagaaggtcg cacatcgtgt ggcttttttg
    85501 attgtttgaa aggtggtgat ggaaaattga gtggattgag aataaaacaa aagagatttg
    85561 cagatgagta catcatctca ggtaatgcga cggaagccta taagaaagca ggttatcgtg
    85621 tttctagtga tagagtggca ggcgttgaag gacataagtt actaaagaat cctaagatta
    85681 aaagctatat agatgaacga ctgaaacaac ttgattctga gaaaattgca gatcagcaag
    85741 aagttcttgg ttatctaaca tcagtaatgc gaggagagac gcaagagcag accttgataa
    85801 gcatcggaga attgggtcaa acgattacgg atattgacgt tggagcaaaa gacagaatca
    85861 aggcagccga actattagga aaacgtcata ggctttggac agacaaagta gaggcagacg
    85921 tttctggaac ggtggtgttt gcaaatgagt cagacatacc agattaagca aaacgatatt
    85981 gtcgttgact tacctaagac agtaggagct gggtacggac agttctggca ctcaagaagt
    86041 ctttatcgtg tagtcaaagg gtcccgtggt tcgaagaagt ccaagacaac cgctttaaac
    86101 tatgttgtcc gtcttttgaa atattcctgg gccaacttgc ttgttattcg taggtattcg
    86161 aatacaaata agcaatcaac ttatacggat tttaaatggg cgtgtaatgt gttgggggtg
    86221 actcatttgt ttaaattcaa tgagtctttg cctgaaataa ccataaaagc gactggtcaa
    86281 aaaatcctat tccgtggttt ggatgatgaa ctcaaaatca catctatcac ggtcgatgtc
    86341 ggcagtcttt gttgggcatg gttcgaggaa gcatatcaaa ttgagactga agacaagttc
    86401 agcacggttg ttgagtctat ccgtggtagc ttagatgtac ctgatttctt taaacaaatc
    86461 acagtcacat ttaacccgtg gaatgagagg cattggctca agcgtgtatt cttcgatgaa
    86521 gagacgagac gggctgacac attcgctact acaaccactt ataaatgcaa tgagtggctt
    86581 gatgaagtcg atatcaaacg ctatgaggat ttgtatcata cgaaccccag acgtgctaga
    86641 atcgtttgtg atggcgaatg gggagttgct gagggtttaa tctatgaaaa cgtgactgtc
    86701 aaggatttca ataaagatga attactacaa gattcagcta ataaattatg tatcggtctt
    86761 gactttggtt ttactcatga tccaactgct ttgtgttgtt cgttgataaa tgatacgacg
    86821 aaagagattt atgtctttga tgaggcgtat aaagtcggat tgataaccaa agaagttgcg
    86881 aagatgataa aggacaaagg ttatcatcgc tcacaaatca ttgctgatag cgcagagtca
    86941 cggctgattg aagagctcag gtcagaacat ggcatatcta gaataaaaga gagtcggaaa
    87001 ggtaaggata gtattatggc aggcgtatcc aaattgcaag gatacgctat ttatgtgcat
    87061 ccagattgta aaaacatcat ggatgaattt tatagttact gctaccagcg agataaagaa
    87121 ggcaactggt tgaataaacc agaggataaa aacaaccact tgatggacgc tttgcgttac
    87181 agccttcaat gtatcgaagg tggaaaagca accgtccgca gacgttctga ttatggtcta
    87241 tagagaggaa agacatgtac caatatttaa cctatccacg ggatggatat gatgagggtt
    87301 ctttgaagaa agacctgatt tacaaattga taacgataca tagcactgaa agctcacatt
    87361 tgaagaagct taaaagctac tatttgggtg agcatgctat cttagaacac acgagacgca
    87421 acgtgaacgc acctaattac aagacggtag ccaatcatgc caaggatatc gcagacacgg
    87481 ctacgggcta ttttatgggc aatcctatca agtataacaa tactgctgac ggtgatatcg
    87541 atgaactact tacagccttt gatggtgctg agattgacca agtagatgct cagaatgctt
    87601 tgaacatggc tatctatggt cgtgcttacg agtacatcta tgctaaagag ggtatggctg
    87661 agttggattc aactagtatt gatccggaga atactttcat ggtctacgat gatagtattg
    87721 agcggaagcc tttgtttgcg gtctattact atgaagtaaa agacgatacg aaagacacta
    87781 ccaagcacca ggctgaggtc tttaccgaaa atctgcacta tcacatggtg ctgagaagta
    87841 cagattcagg aacaactcag agcgaggagg caacacctca caaccttggt caaatcccaa
    87901 ttatcgagta tcgcaacaat cactttgcaa ttggtgacta tgagcaacaa attagcttga
    87961 tagacgctta taattccttg atggggaatc gtgtcaatga taaggaacag gctgtagagt
    88021 ctatacttgt cttgtatggc acgcagttag cagacactcc agaagacgct aaggtagcaa
    88081 tgaagattct ttctgaagaa ggtcttttgg aattgccggg cgatagtgca agggctgagt
    88141 tcttgaagaa tacgctggac gaaagtgcta ctgaaatctt gcgtacagct cttaaagagg
    88201 acatctacac atttagccat gtgcctaatt tgactgatga gaatttcgca gggaatacat
    88261 caggtgtagc catggaattt aagctgatgg gccttgaaat gattactaag accaaggaag
    88321 cgaactataa gcgaggattg cgtcagcgta ttgcgatttt tgctcattac ttaggcatga
    88381 agcagattgc tttagagtct cattcaatcg ttccacaatt cagtcgtggt ttgcctaaga
    88441 acttgttaga aatctctcag atcgtgaaca accttgaagg taaagtgacg aatagacagc
    88501 ttatttctct cttgccgttt gtggaagacc ctgatgctga gctagaagcc ttggaagaag
    88561 agaaaaagaa gaacatggaa gacatgccga tgtttaacca agacaacacg aaacccgaag
    88621 acgaggtaga ggatgaagaa tcaggagtat tgggcgaaga ggaaagccaa tctgatttac
    88681 cagcagatgg acaaggccga aaagcaggca gatcagttcg ataaggtcta tcaggaagcc
    88741 aagacttact tggataagga agtcaataag atttttgata agttccaacg tgattatggt
    88801 ctaagtcagg tagaagctag acaagtcttg aagaacatga aagacaagaa aaatctgaat
    88861 gaacttcgta aagtacttga agcgagaccg aatgatccaa atatccaaag actactggct
    88921 gacttagata gtccggctta ttctttccgt atgaagcgtc tagaacgttt gagtgatgat
    88981 ttagaccgta tgcgtgaatc tatctatcat tcagaaaaga caggctcaga cgccttttat
    89041 agcgacttga tgaaggatag ttactacaag gctacctttg acctgcagca gcagacagga
    89101 ctagcatacg gcttttctgg gcttcctgag agcgagatta aacatctaca gtctttcagt
    89161 tgggtaggag atggaagtac gtactcaaca aacatctgga agaatacagg gaagcttaca
    89221 tcaagcataa aagatgaatt actcataagc cttatgacag gccgagatac acgagaaact
    89281 gcacaagcaa ttgctgagcg gttcaatgtg gggcagaacg atgcaaggcg tttggttcgg
    89341 acagaatcag ccttttttca taaccaaatg gagctactca actatgagga agcggatata
    89401 gagaagtata tctttgtggc cgtcttagac aagcgtacat cacgcatttg tcaggagcat
    89461 gacaatcagg tctatgatag ggataaggct gtccctggtg tcaattgtcc gcctatgcac
    89521 ccttggtgta ggtctactac tgtcggatac gatgaggacg cagactacag caagttgaag
    89581 cgcagagcaa ggaatccaga gacaggtaaa gttgagtacg tgcctgccga tatgacttat
    89641 aaagagtggt atagcaagta tgttgcgaaa gatgtaaaaa atgaaataca agattataag
    89701 aaaagtgaca aaaccgtttc aagatataat accccaaaat tgttttctga tgttagtaac
    89761 gcatgggatg aaattgggag gggtggatta tcgaaagaac aacttgtaga cttgctagaa
    89821 tctgaatatg aattaggtaa tttttcgagc gatatagcaa aattgatagg agtaagttct
    89881 gcttatatag atgttagtag tttagctact tcattagtga gacatggaca acagtattcc
    89941 ttagatgaat ttatgttaat aaaagaggcg gttcaaaaac cttatttgat tctagataat
    90001 tcagagaggg ttgaaaaatc aattatttca tatgtaaaaa tacctaacaa agataaggtc
    90061 attatggaag cggtgatggt gccacgagat gaaatgctag tcattcactt taacaaggtg
    90121 gggattcgtc aagttaaaaa gaatgaaaaa aatatgtcga cgctttacaa aaagggaaaa
    90181 taatgctata ctcttggtaa agatagaggt tgagaatctg tcaccaacgc gccacttata
    90241 gtgggtcgag aaatgcagga gccccgacag tcctgcctat ctgtgcacta aacaatcgtt
    90301 tagtgctttt tttgtactca gaaaggattg aaaatggaca cagcaagaat tgggataact
    90361 aacgtagaat tttcaggaac aggcgaaaat gactcagcga cagtgaaatt agagttaaat
    90421 atttatgggg cggatacgtt cagcgcgatt gagttactac ctaaaatatt aaccgacatt
    90481 cattcattat cgtatgaagt tgattgattg tgacattaaa aggagtgaaa acatgtttat
    90541 atgggattgg gtatcaatcg cctttgggtg gttggtattt ttgttgttaa tatttattat
    90601 tatggccgta atcagcggaa taattaaagg tgtaaagaaa ggaacagaaa aatggaagaa
    90661 tggaaagaaa gatttaaaaa agaatactac gaattgaaag aacgattcca gaagttagat
    90721 atgatgattg ggaaatacga aaaagggcaa ctagagtttg aatctaaatg tccgattgat
    90781 ttgttaaaag gtcagcgttc aaccatgtgg aattatttaa gaattctaga acaacgtgca
    90841 aaaattgaag aaattaaact ataaaaatta accgcatcga aatcgaggcg gttttcttat
    90901 gctctaaccg tatggaatcc cgtacggttt ttatattgtc caaactgtgc cgatgacatt
    90961 aaaagctgta ctgttccgtc gccggacgta aagcgagatt atcgagtggc gacgtaatcg
    91021 ctggaggaca attatgtcag aagaaatcaa tgcaactgta tctactgaat caactgagac
    91081 tgtcgacact caaggaaatg ttgattcagt gcaggaagaa aagcacgaac gaactttcac
    91141 tcgtgctgaa atcggtaaga tgctatctgc cgagcgctct aaatgggaag ctgagcaaga
    91201 agccaaggaa aacgaagcca agaaacttgc caagatgaac gctgacgaga aacagaaata
    91261 tcagttggat cagcgtgagc aagaactagc tgaccgtgag aaggctattg ctcgcaagga
    91321 attgaccgca gaagctaaag caatgctaag tgaacgtgac ttacctgttg agttagtaaa
    91381 tgtagttgat ttgacaagcg cagagacggt atcgcagtct gtcgctgtat tgcagaaatc
    91441 atgggagcaa gccgtgcaaa aaggcgttca agaaaaacta aaaggcggag ctccaatgaa
    91501 acaagcgcca gtcgatagtg acggtatcac aaaagaagaa tttgctcgta tgggttatca
    91561 gagtcgaaat gagctctatc aaaagaaccc agagctttat aagaaattga aaggataata
    91621 gaaaatgaca gcaggacaaa ctaaattagc cactatggtt aatccagaag taatggcgga
    91681 tatggtagcc gctaaattac ctaaattgat taaatttaca ccgctagcgt atgtagagac
    91741 aaagcttgaa ggtcaaccag gtagcacttt aacagtgcca gcatgggagt atgcaggaga
    91801 cgctactgaa attgaagaag gccaagcaat tacgccagac caattgacta ctaaaaagac
    91861 tactatgacc atcaaaaaag caggtaaagg ttatgaaatt accgatgagt ctcttttgtc
    91921 aggtcttggt gacccactag gtcaagcgac ttaccagctt ggtttagcta ttgccaacaa
    91981 gatcgataat gatttggtag cggtagctaa aactgcaaca caacatatta cagaaactcc
    92041 aacaactctt gaggcaatcg ataaagctct agatatcttt gaggacgaag aagatgcaca
    92101 gtatgttgct atcatcaacc ctaaagatgc tactaagcta aaaactgcag tagcaaaaga
    92161 atggattaaa ggttcagagc ttggagcaaa tatggttgtt tctggaacct tcggtgaagt
    92221 tgatggtgtg caaatcgtgc gctctaaaaa agttgatgaa ggtaaaggct tccttgttaa
    92281 agtgtcacca agtcaaactc agacagacga cgctaacaaa tatggagctt ttgttatctt
    92341 gcttaaacgt gatgtggcta tcgaaacaga ccgcgatatc ttgaagaaga ctaccgtaat
    92401 cacaggtgat gaacactacg gcgtttacct ttacgaccct acacgagttg taaaattcgg
    92461 tggcgcgtaa gaggtgacga tatgagttta ttgctacgac gtcattatat tcaagaagag
    92521 caggttaacc agtattctga tttagagaat aaaactctag aagagttgaa ggatctagcg
    92581 aaagaagcag gtgtagcagg cgcttataag ttgacaaaag ccgaaattgt agaagttttg
    92641 gaggaactaa aaagtgaaat ttaaaatcaa acaagatttc tatgattggg aatcaaatgt
    92701 gaaacgactg gcaggagagg aacttgagat tactgaggag cgctatgctg agctggctga
    92761 caatattgcc agcaacggtg tcgctatctc agatgttctt gaggaaatct ttcctaaacc
    92821 tgagttctta gaagaggatt gatatgtcta tagagttgct gaagaaatta acaggcgaag
    92881 aagatactca gcttctcatg ttgctccaaa caagggctac aaatcttatc ttgtcagaga
    92941 ctaatcgcac atctttgaca cctgctttaa gtcttttaat acctgaggtt gctatcgagc
    93001 tccacaaccg ctcaggagcg gaaggagagc gttctagaac cgaaggtggt atagcagtag
    93061 tctacggaga aaatggcctg tctacgggtc ttctacagcg aatacgcatg cacaggctag
    93121 caagggtggc aggtcatgtt tttgaagcag agtagactga aaccttatcc aatgcgacgg
    93181 tttgaaaaga ctgtcactga ggaaggtgtc gcgaaagaag ggtatgccaa ggaagctgag
    93241 acagtccgcc ttgaattgtg gccagctagt agcaagctac aatctgaatt gtatggcgag
    93301 cgtgtcaatg atattttgaa cgcaaatgcc aacaagtcag ctacaatcaa agtgaaagat
    93361 ggtgtgtgta tcgatagcca gacagaagtg actcacaggg ttatttctaa aaaggtctac
    93421 acacatcatc aagttttgga gttagagcgt gtcagggcta ctaggggcag ataggctcat
    93481 agctaaatgt agacgattgg ctagtaaaaa aactggcgag gatatcgtct tacgtgcggt
    93541 acacaatgct actataaagg ttgtccaagc agatgcaaga agactcgcac cagcgagaga
    93601 tggagagctt ataactagta tcaaaactag ggcaaaaatg gacggagata aggctatagg
    93661 cgaggtttac accaacctaa aatacgctcc ttacgttgag tttggaacgg gaccaaaagg
    93721 acaagctagc cattctggta tctctccaga ggtcagcgta acttacaagt ctagtccgtg
    93781 gtatgtgcat gaagaccaaa tcaatgtagg accttaccac tttcaaaaga ttggggagtt
    93841 ctacaagatg tatggtcaac ctgcccagcc ttatctttat ccagctttga gagacaatca
    93901 agagcgtgtg tctaagaata tttcgaatta tgtccgtaga aagataagag aacaaataaa
    93961 atgattaata tcaagcctgt tatttataaa gaattgcaaa aggtcgcaga taatgtgact
    94021 gatacttatc ctagcgattg ggagactttc ccagtcgtta tttttttaga agaacaaaac
    94081 aagccgggtg attggtttga tgaccaggaa caaaaatcat ctatccgcta taaggtggat
    94141 atctttgatg ataccagcac tagtgagtta gctgttaaaa tcaatcagat ttttgagtct
    94201 ttaggtttgc gaagaaccga ctgccaagac gtgccagacc cgtctcattt gagacataag
    94261 gtcatgcgct ttgaaggtgt cgttgattta gactcagagc ttgtttttca atttagaatg
    94321 gagaattaaa catgttagca aatggaatta cgctatctta tggcgaagct aaaggaactt
    94381 atactaaact tgttggattg aaagaagtgc cagagtttgg tattgaactc gaaaaagtag
    94441 aaaatactac tcttgaagat acagtgaaga agtacgagtt tggtattggg gacataggag
    94501 aacttgagta caagttctct tataataatt caagcgcaac tgctccttat cgtgtattgc
    94561 gtaaggcagc agacgacaag aagaaactct acttcgagca agcataccca gacggtacta
    94621 aggtcaattt tgaaggccaa gtatctgtta agcttggcgg tggcggtgtc aatgccgtta
    94681 tcgagttcac acttaagatt gccttgcagt cagagttgga atttacagac ggtgttggag
    94741 gttaattaaa tggcgttaaa atacacaact tggaaagtta ctgacgaaaa agagttgaag
    94801 ctacgtttga catctcatca agctgcaact gtggaagaaa aaatcggcat gaacttgtta
    94861 aagattttca tgcctgaagc tggcgaagag ttcactttac cgcctttgaa agttatgctg
    94921 ttgttagttc atggagcctt gcagcagtat gaacatgggt attcctttga agatgtctac
    94981 gacctatacg atgaatacgt ggacaatggg ggagaccaaa caactttcat gacagaggtt
    95041 ttaatgccac tatttgaagt atcgggtttt actccacgag gaagcaagaa caagaaaact
    95101 tccaagaaga aaatgacagt agtcgagtaa tcttaacagt aacgcagatt attgagaggc
    95161 tttatcctat gtttttggac attggaggca agcctcttga tttttgggat ttgacggtgc
    95221 ttgaaatcag agaaatgatt gaaagctaca accgtgtcaa aacccaagag cgtaaagaga
    95281 agattattga ctcatacaga ctttcgcaga tgatttccaa tcacgtttct ttattactgt
    95341 ccaatgacgc taagattgtt gagttctggg agtatgcgcc tgagttattt gtagaagaac
    95401 aacaagcggt agaactggaa cgacagaaac aagcactttt gttgcataag gaacggatgc
    95461 gtgaatttgc agagagacat aatcgaaaaa ggaaggagga agtaaatggc aactcttgat
    95521 gaattgaaag tcatgattga cgctgagata gcgcctttca ggaaaaagat gaaagaagtc
    95581 gagaatcagg tcaaaggaac atctgaccga gtgaaaaatg ccactgccaa agttcgtgaa
    95641 cagtcgaact caatcggtag tgcgtttggt aagctggcta agttcgctgg ttttgcaatc
    95701 cttggtaaga aattacttga tgttgggatg tattcaacgc agacggctct tgaagtatca
    95761 gcgtctatga accaaatcaa gcgacagatg ggcgagagtt cgcaatcttt cttaaaatgg
    95821 gttaacgata acgccaacgc tatgaatatg ggtgtgggtg aggctactaa ctacggtgcg
    95881 gtctactcaa acttattttc tgggtttatc aaagatacca acaagctagg cgcctatacc
    95941 gctaagatgt tgcagacatc ggcagttgtt gctgaaggtt cagggcgcac gattacagac
    96001 gttatggagc ggattcgctc aggtctacta gggaacaccg aagcgattga ggatctagga
    96061 atcaacgtca atgtggctat gattaagtcc actgaagctt ttaaacgttt ctcaaatggt
    96121 caaagttggg accaactcga ctttcaaacc cagcaacaaa tccgtcttat ggctatcctg
    96181 gagcaagcta cagccaagta tggggatacc ttgtctaatt ctgtaaatgg tcgtatcagc
    96241 ctatttaagt cgctgatgaa ggacgcagca ttgaaccttg gtaactctat gttaccgatt
    96301 atcaatgcca ttatgcctgt cttgaactct tttgctatgg tcttaaagaa cgttactgct
    96361 aaactcgctg agtttatcgc tttgatgttc aacaagaaag caacagtgaa agatggtgtt
    96421 ggtggagcag ttggagacat gggtaacgcc atgaaggatg ctgcaggcgg agcaggagac
    96481 cttgctgacg cagtagacga cgctggagat tcagcaggag gacttgctga caatcttgga
    96541 gactccgcca aaaacgctaa gaaggccgct aaagagttgc taggtctttt gggatttgat
    96601 gagattaaca tcttgcaaaa accaaaagat gacgacgcag gcgggtctgg aggcggtggc
    96661 aaaggtggta aaggaaaggg aggcggtggc ggacctttca aagacatctt gccagaagtc
    96721 gagttgaccg acatggacaa caaattcaag agcatttttg atggtcttgg agataagctc
    96781 aaagggttgt ttgacctctt caagaaaggt tttgatgcag catttagacc agaaggtata
    96841 gaacgcatta agactgcctt agaccaaata gctaagacaa tgggagaaat cgccactgac
    96901 ccaagggttg tgaatgcctt taaccgaatg gctgagaaaa ttgcttatgc tttagggcaa
    96961 gtgacaggct caataacaac tatcgggcta ggtatcggtg ttttccttgc cgaaagtatt
    97021 gcaaatggcc ttggaaggca aaaagaacgc attatcaggg cgctagtcgc tttgtttgat
    97081 aatgttggta acctttccga ggcagtagga aacatagctc aggacttttc tagtgctttc
    97141 tacgacgtca ttacctcaac tggtgcggtt cgtatcggta gcgctattgt gtcaactctg
    97201 ttgagtttga catctaccat tgttgaagtt ggtagtaaat tagcaggaag tttgtttaaa
    97261 ggttttgaaa aagtcgttgt gacaagcgct cctaaaattt catcagtctt ccaaagttta
    97321 ttagatactg ttgcgcctgt atttgagagc attgaaaggt ctgttaacaa atttggcgat
    97381 ggcttaagtc gtgtttatga tgaacatgta gtccctgcta ttaactctat tgctaatgct
    97441 tttaatgggc taattgacat tattcaaata ctttgggaag gaagttggaa gccttttgca
    97501 gagttcttgt ctaacacatt cggcataagt attgaaaccg tcgctgattt actaggcggt
    97561 atcatactag aggcattgaa gttactagct gatacaatca agctagtaac cgatggtttt
    97621 actgcttttt cagattggtg taaagaaaat aaagagatta tctccacaat cgctagtgtg
    97681 attggtacgc ttgcaaccgt gtggcaagga attaagttct tgtcttgggc tgaacaagct
    97741 ggaggacttg caggggcatt cgaattatta agtagtaagg tttcctttat tgttagcgga
    97801 attaaaaatc ttggactagc tttgaaagct ttgacatttg ataaattggt cagcttcgga
    97861 gaaaccatct atttgaatgc gttgtatgca aaagattttg ttgtcaattc aggtaaaaca
    97921 attgcacagc tagggaaaac tgctttagaa cttggtaaat cagctctagc atggactgct
    97981 catacagcga aaatgggatt agcaaccgcg gcggaatttg cacattctgt tgcagcagga
    98041 gtcgctacag ctgcaacatg ggcttttaat gcagcgttag cagttttgac aagtccaata
    98101 accttagtta ttgcagcaat cgcagcctta attggtatcg gtgtcttgct ctaccaaaat
    98161 tgggacactg ttgttgagtt tgctaaaact gcatggcaag gactatgtga ttttatcagt
    98221 ggtatttgtc aagcgattgg cgaatttttc agcggtctat ggacgaaact ccaagaaatc
    98281 tttgagccaa taggtcaatg gtttagcgag aagttccagc aagcatggga tgctattgga
    98341 aatatatttg gcaacttagg ctcttggttt ggtggccgtt ggaatgattc taaaaacgca
    98401 cttgccgaag caaatacttg gcttggtgat aagttcaagt caggtcggga taaagtgaac
    98461 tcagcttttg aaaaagttgg ctcttggttc ggtgaccgtt ggaatgatat caaagatgga
    98521 gtgaaagaag ctgatacatg gtttggagag aaatttgaga gtgcaaaaaa gaaaactcag
    98581 aatcctttcc aaaaaatcgg ttcttggttt ggcgatagat ggaaagatat gcaagatgcc
    98641 ttgaaagaaa tccccaactg gttcaagaat ctgtttaatg atgcaatgga taatgctaaa
    98701 aacatcgtta aaagtggtat cgataaacta aaaagcttct ttaactttga ttggagctta
    98761 ccaaaaatca aactccctca ctttaatata tctggtagct tcagcttgat gcctcctaga
    98821 attccatcat tctctgtaga ttggtatgca cgaggtggtg tattcaactc tcctagcatc
    98881 attggggtcg gagaagctgg tcaagaagcg gtaatgcctc ttgaacggaa tacaggatgg
    98941 atttctatct tggctcaaaa actggctgaa agaatgcctg ctaataatgt acctacaggt
    99001 tattcattac cggctggcga catcgttatc caaatcgcag gacatgagtt cggtcgggta
    99061 gcaatccaag aaatcaacaa ggagcatgaa cgagcaggtc aaaccttgct caagatttag
    99121 gaggttaaat ggcacaattg acaatcaatg gggtggctgt gaagcctccc aaatcttttc
    99181 aagtcggtat tcaagatatc gatggagaga cagggcgtaa tgccaatggc gacatgatgc
    99241 gtgaccgtat cacgaccaaa cgcaaactag actgtgaatg gggtatgatg actcagggag
    99301 aattaagtca gcttttacat gctgtatcat ctgaattttt tgaggtgtct tatccagacc
    99361 ccatggatgg ccaagtcaca aagactttct atgtcggtga taggacagct cctagatata
    99421 cctttactga gaagtttaaa ccttggtctg gcgctaaatt taatctggta gagaggtaag
    99481 aaaatggacg ctttaactag acgacaattt gacagagcca tgtttgccaa ggaaaggacg
    99541 ctggctattc gtgttggtga ttatgcttca cgggatatca aagaggctag ttttgagtat
    99601 ggctacatta agggcgatac ttataagcct ggtggaacct gcgctggtag cggtaaaatt
    99661 acctttacca gtatcattac cacgttcaat aagctggata ccctgcaccc tgagattggt
    99721 ctactggttg gggataccta ccagtgggtc aagatggggg aatacttcat caacgatatt
    99781 gagattgacc gaaaccgaaa cactaccaca cttgaactta tggatggtat gtttaagctc
    99841 aatcgtgagt atgtgacaga tttgcatttc ccagctgaag tacgagaggt tattcaggaa
    99901 atctgcctga aaacaggcat tgagttagcg aatgactatt tcggaatcag cgcgatgcgt
    99961 tatcatattg agcaagttcc tgagggcaag aaactttcct ttagggatat gctgagcgct
   100021 atgactcaga tgattgggat gtcttgtttc ttcaacagag aaggcaagat ggaaatccgt
   100081 gatttgactg agtccaatat cacgatcaac gctgacagtt acttcttgca tggcttgacc
   100141 aagagtgaga ttgagtatca gatagctggt atcacttgta agacggacaa gaagtctctg
   100201 acggtcggta tgaagacagg ccggtctttg gaactggaca atgtcttcat gacccagagc
   100261 gctttaaatg acctgtatta caaactgaaa aacctaactt actatccgta taatctcaac
   100321 taccaagggc atttactgct tgaggtcggg cagtgggtaa ccattcagac caataagaaa
   100381 gagaccttta aagttcctgt gttaagtcag agctttactt ttaaaggtgg tctgagaggg
   100441 cgtatcagcg cagatagtaa ggctggaaac gatactcagt attcttacga gggtacgatt
   100501 accaagcata ttaagcaaca agatggcatt gaagcgaaaa tccaagcgca gattgaagca
   100561 gcagataaag attttgacca aaaggttgac aaaatcaaaa aagactttaa cgatcaagta
   100621 gaactggcca aagccagagc tgaagaagtc aagagagaac tgtctgacac tatcaatcag
   100681 cgatttaata gttttgacaa cgggccattg aaagaaacta agcgcaaggc tgaggaagct
   100741 ttgcgaaatg ctggcgcaag taccctgctt gcacaggaag ctaagcggat tgggctggat
   100801 tctgtcgcta gacttgaagc gtttaagtcg cagactacga gcgcacaaac ggctctgtcg
   100861 ggtgacttgg acgctctgaa acggactatc gcgaatgata ttcgaccgaa gcaagcacag
   100921 gctgaaactg agattgccaa gcaagttgaa gcacttagcc ggactaaaaa tgaactggct
   100981 ggcgtgaagt cagcgcaagc gacgtatgag gagacgacga ctcgtagact gtcagaactg
   101041 accaacttgg ccaatggtaa agccagcaag tcagaactca cgcagacagc tgaggagcta
   101101 gctagtaaga tagcgagtgt gcaggtcggg ggtaggaatt atatccgggg tacaaagcgc
   101161 atgatgctag ccagaggatt gtgggcatca ggtactttta gaccgtcagg cgctgggacg
   101221 gcaaagacga ttgatgtatc agacagtcca gtaactggct ttgataaagc gatacgattg
   101281 acctcaagca atgctagaga ccaaataggt attgctcaag atggatttta tatctcgcaa
   101341 ggcacataca cgatgtcttg ttgggtcaaa ggcagaagag gtcaaaaggt caagctacaa
   101401 acttattggc aagtccatga taattcgggt atttcaccca tctttacatt aaaggatgaa
   101461 aattggacaa agctatcgtt tactagcgct agaaataggg ctggagtcgc atcaattggc
   101521 tatgtgtatc tcgtaaatgc tgaggtcgga gaatatttag atgttcttgc gccccagctg
   101581 gaagacggaa gtttggcaac aagctcaa
//
LOCUS       DAVLMQ010000003        90332 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000003 DAVLMQ010000000
VERSION     DAVLMQ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 90332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90332
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.003"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VXF95_000237"
     CDS             complement(<1..1954)
                     /gene="ftsH"
                     /locus_tag="VXF95_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HEV1080847.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEGTGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMLGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNRETHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDE"
     gene            complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VXF95_000238"
     CDS             complement(1970..2512)
                     /gene="hpt"
                     /locus_tag="VXF95_000238"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HEV1080848.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VXF95_000239"
     CDS             complement(2516..3793)
                     /gene="tilS"
                     /locus_tag="VXF95_000239"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HEV1080849.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEKEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3790..5058)
                     /locus_tag="VXF95_000240"
     CDS             complement(3790..5058)
                     /locus_tag="VXF95_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HEV1080850.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGELTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKVWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5178..5546)
                     /locus_tag="VXF95_000241"
     CDS             complement(5178..5546)
                     /locus_tag="VXF95_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HEV1080851.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5539..5805)
                     /locus_tag="VXF95_000242"
     CDS             complement(5539..5805)
                     /locus_tag="VXF95_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HEV1080852.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VXF95_000243"
     CDS             complement(5863..9372)
                     /gene="mfd"
                     /locus_tag="VXF95_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HEV1080853.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLMSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYDQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTNICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNIDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKELMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9373..9942)
                     /locus_tag="VXF95_000244"
     CDS             complement(9373..9942)
                     /locus_tag="VXF95_000244"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HEV1080854.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDEYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VXF95_000245"
     CDS             complement(10013..11128)
                     /gene="ychF"
                     /locus_tag="VXF95_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HEV1080855.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11248..12414)
                     /locus_tag="VXF95_000246"
     CDS             complement(11248..12414)
                     /locus_tag="VXF95_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1080856.1"
                     /translation="MKITEYTKKDGSTVYRSSVYLGIDTVTGKKVKTTISGRTKRELK
                     AKALQAQIDFEKGGATVYKAVEIKTYAELVENWLETYCHTVKKSTLMGTKFKIDKYLL
                     PAFGNYRLDKLTPPIIQKQVNQWAKDYNQLGKGFQEYPLLHSLNKRILKYAVSLQAIP
                     FNPARDVIVPRRKEKEGQKLKYLDDDNLKKFLTYLEQLPNTYKNFYDTVLYKTLLATG
                     LRIRECLALKWSDIDLKNGTLDVNKTLNIIKEITVPKTKSSIRVIDLDNKTVLMLRLY
                     KARQSQIGKEMGLTYEKVFSNSFDKHIDARMLSFRLVKHLERAGCPRFTFHAFRHTHA
                     SILLNAGLPYKEIQTRLGHAKLSMTMDIYSHLSKDNQKNATSFYEKAIEKLKSS"
     gene            complement(13120..13788)
                     /locus_tag="VXF95_000247"
     CDS             complement(13120..13788)
                     /locus_tag="VXF95_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000666925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HEV1080857.1"
                     /translation="MKFCPECGNSVVGCKFCPNCGYSINASLKTTPQKVATPSSRPST
                     VRSKRTDKVGPLEIDKNHRTYRIHGARKAKGSSGLIGGTAKVVGKTTLALGTGGLSLI
                     PSLIKKDKNDTDWYSFDDLVSYELVINDQSVVSGGVGQALVAGAVFGVIGAVAGGIVA
                     KRKATTKILNMTIRITSNDFTKPVVFIDLIKKPVKNTSKEYKEAIENAQKIIGALDVI
                     THNS"
     gene            complement(13807..14523)
                     /locus_tag="VXF95_000248"
     CDS             complement(13807..14523)
                     /locus_tag="VXF95_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080858.1"
                     /translation="MADNIKRLLSAKGLNPRQLAIALDFKYTTVNDWVNAKTYPRIDK
                     IEMLANFFNVSKSDLVENKNAETPTTSPIQSIYDQLTPPRQEKALTYLKKQLLEQKNE
                     NIVSENIISLDDYRESKTLPVIGVVTAGNGITQDDNLNIEKCFYTDEIPDDYDAIAYV
                     VGNSMEPKIKNGDYLFIKNTPQVDYNTIGIFQVDGANYVKKLRQGYLESLNPECADIQ
                     LDESNDIRTIGEVVGIYREK"
     gene            14727..14918
                     /locus_tag="VXF95_000249"
     CDS             14727..14918
                     /locus_tag="VXF95_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1080859.1"
                     /translation="MRLTLKALRANSNMKQSEVAQKLGISTTTWSKWENGKSFPDVAQ
                     VKEIEKLFGVAYDDIIFLS"
     gene            14993..15370
                     /locus_tag="VXF95_000250"
     CDS             14993..15370
                     /locus_tag="VXF95_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080860.1"
                     /translation="MLYHWGLTFSEEISDLEHKGENNMNNKQVYQAQTTDHGIARALG
                     EEIRMITDVEETTYNGHGEIIVEYTSDVALTKLFDRIKALYEKGESYETKPFLHFKVL
                     EDDIEPSPNGVFTAKEVAEFLGI"
     gene            15392..16018
                     /locus_tag="VXF95_000251"
     CDS             15392..16018
                     /locus_tag="VXF95_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV1080861.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVRKFKMNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIENWEQAPKHAHSTMNNLLLKAVTDRNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            16288..16461
                     /locus_tag="VXF95_000252"
     CDS             16288..16461
                     /locus_tag="VXF95_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1080862.1"
                     /translation="MTDKIKKVGRPKGENSNTVKLTVRVSEQLNSKLEEYGKKNGLTK
                     PETLRKAFENLTK"
     gene            16615..17022
                     /locus_tag="VXF95_000253"
     CDS             16615..17022
                     /locus_tag="VXF95_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080863.1"
                     /translation="MGKQVFTQEILRNIQEENGIITVDLILDALPTWSEKAIKGRLSN
                     WRYRKVIDYRVEDGEFSEIFLLRSKQEIKEEVSAGQRLKMDLYFRQVLALTGIIESNT
                     SKDNDKTKAIELQQKAMRAIPDDIYKELSEIYE"
     gene            17516..18016
                     /locus_tag="VXF95_000254"
     CDS             17516..18016
                     /locus_tag="VXF95_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080864.1"
                     /translation="MIADQLKAISTNLEEIQEILVGDGTALAKREISRVLNDLDDVYN
                     ELTSTEYREQQETLKEQTERMKQRVVAEVIGGLEEREESYYRNYWGDTKFIKLLSNFD
                     GFLFLNTYLAEITKENTYPMEQSQLLNYVWEVIAVDIAKKKRGKKNVLDSWTDSSLYT
                     RGMMID"
     gene            18028..18168
                     /locus_tag="VXF95_000255"
     CDS             18028..18168
                     /locus_tag="VXF95_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080865.1"
                     /translation="MTLDLGKMTQAEFDEVMADIKARNPNLLQFITDFLDRKVTPGEV
                     DD"
     gene            18230..18445
                     /locus_tag="VXF95_000256"
     CDS             18230..18445
                     /locus_tag="VXF95_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080866.1"
                     /translation="MNELDISNTQAAVLIVILIGLLLYLNHRDRKKSAQIERENQQTI
                     KTPSEDLNPEYGRYIQLAGVNVWGGME"
     gene            18442..18738
                     /locus_tag="VXF95_000257"
     CDS             18442..18738
                     /locus_tag="VXF95_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001106820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080867.1"
                     /translation="MSYIVKIYLDSEKIPDEPYFTKEIFLATCMGNATKLAVTMGLLT
                     KQVLDLETKTAILKALDTIIETQKAILQGVASGQITFVNKSKREEELDEPIRER"
     gene            18716..19057
                     /locus_tag="VXF95_000258"
     CDS             18716..19057
                     /locus_tag="VXF95_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1080868.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGSEISLTTKLTERTVRDIIKR
                     LVVKHNIPIVGVRCGVFSGYFIPANKGELLDGAKAFYNQVQEESKRLAVLMNSDLESY
                     KETLKEVGGYV"
     gene            19050..19323
                     /locus_tag="VXF95_000259"
                     /pseudo
     CDS             19050..19323
                     /locus_tag="VXF95_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            19320..20180
                     /locus_tag="VXF95_000260"
     CDS             19320..20180
                     /locus_tag="VXF95_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV1080869.1"
                     /translation="MTIYEARGFQSNLVYPFDKIEPFQYIERFKPLVVPESADTEEYK
                     RTQAPYCLSGKVMPEKNGSYKRNNSSLIYRDLIFLDYDDIQGTTEDFIEAVSSALFGY
                     SYILYPTIKHSIEKPRFRLVVKSNNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPATYQKIVEHGLDYPVPKVEPRAKQGTTERYKPRVSGQRSMTMRIIDTLF
                     NGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTFSS
                     IARAEYRKRG"
     gene            20260..21714
                     /locus_tag="VXF95_000261"
     CDS             20260..21714
                     /locus_tag="VXF95_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV1080870.1"
                     /translation="MWELYSRIWELGDQWRKENSYIVNEGKKNERVEIPRPSVAIVAK
                     ALQEICHFTFIGEGVISDISKLYLYHLDLGHYVSSNDIFRKLLLKYDSRLTSNKFFLE
                     LISYIRTETKMKPPLDDYRYIPVANGVYNIKTHKLEEFSPNFVITSKIQTEYKPCARK
                     PILDGWFDFDRWLEALAVNDKEVVALLWQVINEAINPNRTRKKMVLMVGDGNNGKGTF
                     QSLLENLIGRSNISNLKPDQFGKEFYLGALEGKVCNIGDDISNKYLDEVSDLMSVISG
                     DPVQVNKKSLQPVEARFRLLCIFSGNDLPRARNKTMGWYRRLCIIPFRADFNGQKERH
                     EIKDRFIKNKELLEWVLFKVLNMPDFDSFIEPEAVQKMLSKYKNDNDYIKVWVENFYI
                     PNGWHEINHVPMFIARNKLKEFAEDIGIDKPKLGQFSNAVMAELEKTTSYKYSAKNGT
                     VSSKFYDVLDPQGFQRKRFVKGIWGIHLEDEDLG"
     gene            22315..22839
                     /locus_tag="VXF95_000262"
     CDS             22315..22839
                     /locus_tag="VXF95_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080871.1"
                     /translation="MTLKTFSDKAKTFNFTYEFKDQDTAQVAGSALMGYMIGTYVVPS
                     ISITYKNKGTLVAEYVEDHKLNKTFKRICDGFKDYYKQPEGDEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELKLLDYAERLLSDKPILMNSMTAFGTLEVLGNESINLFQKLD
                     VEGEYKGLADYSGQ"
     gene            22902..23168
                     /locus_tag="VXF95_000263"
     CDS             22902..23168
                     /locus_tag="VXF95_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080872.1"
                     /translation="MVRSLKARLEKLEEYAGKTEYATTDECISLYVDCLRFAFQQDEI
                     KIDMDDFIKTPFKDIKLADYKKSKKRMDELREMTGISEFSELEQ"
     gene            23219..23560
                     /locus_tag="VXF95_000264"
     CDS             23219..23560
                     /locus_tag="VXF95_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000035041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV1080873.1"
                     /translation="MANYLMTGNVKKASELSEITRKTAYNYLNDATFKRIYRERRSEQ
                     LKESTTLLQNASVEAVNVLREIMLDKTVSPYARQQSAQSILNMAYKAVEMVEVVEQLE
                     ILEAKILDEGD"
     gene            23547..23798
                     /locus_tag="VXF95_000265"
     CDS             23547..23798
                     /locus_tag="VXF95_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080874.1"
                     /translation="MKAIKNRLNKLNKLAVVDEVDTVFLTQIDTGHFEVRYRIGGKNP
                     KDIIEVYPTKEEAEKAISEIKNTKGLRIFWDNLALLEDN"
     gene            complement(24237..24578)
                     /locus_tag="VXF95_000266"
                     /pseudo
     CDS             complement(24237..24578)
                     /locus_tag="VXF95_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117663.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
     gene            complement(25521..25664)
                     /locus_tag="VXF95_000267"
     CDS             complement(25521..25664)
                     /locus_tag="VXF95_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080875.1"
                     /translation="MNEYKEIMENVNQAKEELKRIDELIAVRSSRIDFLEDKTLRITG
                     NQR"
     gene            26013..26198
                     /locus_tag="VXF95_000268"
                     /pseudo
     CDS             26013..26198
                     /locus_tag="VXF95_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255647.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            26480..26638
                     /locus_tag="VXF95_000269"
     CDS             26480..26638
                     /locus_tag="VXF95_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080876.1"
                     /translation="MIEDFLIDLENIQLEDMEIDFNMEIDIDLNIDFEIDVDLDGLDL
                     TLLQELEA"
     gene            complement(27070..27264)
                     /locus_tag="VXF95_000270"
     CDS             complement(27070..27264)
                     /locus_tag="VXF95_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HEV1080877.1"
                     /translation="MYQVGNFVEMKKSHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(27329..28465)
                     /gene="dnaN"
                     /locus_tag="VXF95_000271"
     CDS             complement(27329..28465)
                     /gene="dnaN"
                     /locus_tag="VXF95_000271"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HEV1080878.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(28624..29985)
                     /gene="dnaA"
                     /locus_tag="VXF95_000272"
     CDS             complement(28624..29985)
                     /gene="dnaA"
                     /locus_tag="VXF95_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HEV1080879.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAELIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(30198..30956)
                     /locus_tag="VXF95_000273"
     CDS             complement(30198..30956)
                     /locus_tag="VXF95_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HEV1080880.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLETLLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(31014..32195)
                     /locus_tag="VXF95_000274"
     CDS             complement(31014..32195)
                     /locus_tag="VXF95_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1080881.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGEIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLRSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVVVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            32378..32857
                     /gene="rlmH"
                     /locus_tag="VXF95_000275"
     CDS             32378..32857
                     /gene="rlmH"
                     /locus_tag="VXF95_000275"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HEV1080882.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRLTLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            32901..32974
                     /locus_tag="VXF95_000276"
     tRNA            32901..32974
                     /locus_tag="VXF95_000276"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32935..32937,aa:Arg,seq:tct)
     gene            33139..33264
                     /gene="comC"
                     /locus_tag="VXF95_000277"
     CDS             33139..33264
                     /gene="comC"
                     /locus_tag="VXF95_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HEV1080883.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            33285..34610
                     /locus_tag="VXF95_000278"
     CDS             33285..34610
                     /locus_tag="VXF95_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1080884.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            34607..35359
                     /locus_tag="VXF95_000279"
     CDS             34607..35359
                     /locus_tag="VXF95_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1080885.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            35411..35482
                     /locus_tag="VXF95_000280"
     tRNA            35411..35482
                     /locus_tag="VXF95_000280"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35444..35446,aa:Glu,seq:ttc)
     gene            35488..35561
                     /locus_tag="VXF95_000281"
     tRNA            35488..35561
                     /locus_tag="VXF95_000281"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35522..35524,aa:Asn,seq:gtt)
     gene            complement(35602..36144)
                     /locus_tag="VXF95_000282"
     CDS             complement(35602..36144)
                     /locus_tag="VXF95_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HEV1080886.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            36251..37428
                     /locus_tag="VXF95_000283"
                     /pseudo
     CDS             36251..37428
                     /locus_tag="VXF95_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518194.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
     gene            complement(37458..40010)
                     /locus_tag="VXF95_000284"
     CDS             complement(37458..40010)
                     /locus_tag="VXF95_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HEV1080887.1"
                     /translation="MKSFLKTYRTYFISFIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLLPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDIPAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPISYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(40072..41694)
                     /locus_tag="VXF95_000285"
     CDS             complement(40072..41694)
                     /locus_tag="VXF95_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1080888.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEDDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            41900..42925
                     /gene="trpS"
                     /locus_tag="VXF95_000286"
     CDS             41900..42925
                     /gene="trpS"
                     /locus_tag="VXF95_000286"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HEV1080889.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            43077..44555
                     /gene="guaB"
                     /locus_tag="VXF95_000287"
     CDS             43077..44555
                     /gene="guaB"
                     /locus_tag="VXF95_000287"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HEV1080890.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(44606..45703)
                     /gene="recF"
                     /locus_tag="VXF95_000288"
     CDS             complement(44606..45703)
                     /gene="recF"
                     /locus_tag="VXF95_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HEV1080891.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKAAVNGN"
     gene            complement(45706..46074)
                     /gene="yaaA"
                     /locus_tag="VXF95_000289"
     CDS             complement(45706..46074)
                     /gene="yaaA"
                     /locus_tag="VXF95_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HEV1080892.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            46233..47483
                     /locus_tag="VXF95_000290"
     CDS             46233..47483
                     /locus_tag="VXF95_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1080893.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPVVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAKLEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            47480..48763
                     /locus_tag="VXF95_000291"
     CDS             47480..48763
                     /locus_tag="VXF95_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HEV1080894.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGDVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSIGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKLTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTMDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            48805..49626
                     /locus_tag="VXF95_000292"
     CDS             48805..49626
                     /locus_tag="VXF95_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080895.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            49637..50182
                     /gene="pgsA"
                     /locus_tag="VXF95_000293"
     CDS             49637..50182
                     /gene="pgsA"
                     /locus_tag="VXF95_000293"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HEV1080896.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            50179..51006
                     /locus_tag="VXF95_000294"
     CDS             50179..51006
                     /locus_tag="VXF95_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1080897.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            50991..51830
                     /locus_tag="VXF95_000295"
     CDS             50991..51830
                     /locus_tag="VXF95_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HEV1080898.1"
                     /translation="MGIALENVNFTYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPNQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPAILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            51823..52617
                     /locus_tag="VXF95_000296"
     CDS             51823..52617
                     /locus_tag="VXF95_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1080899.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            52676..53494
                     /gene="mreC"
                     /locus_tag="VXF95_000297"
     CDS             52676..53494
                     /gene="mreC"
                     /locus_tag="VXF95_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HEV1080900.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            53494..53988
                     /gene="mreD"
                     /locus_tag="VXF95_000298"
     CDS             53494..53988
                     /gene="mreD"
                     /locus_tag="VXF95_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HEV1080901.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            54082..55260
                     /locus_tag="VXF95_000299"
     CDS             54082..55260
                     /locus_tag="VXF95_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HEV1080902.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINIVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            55484..56263
                     /gene="rpsB"
                     /locus_tag="VXF95_000300"
     CDS             55484..56263
                     /gene="rpsB"
                     /locus_tag="VXF95_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HEV1080903.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            56342..57382
                     /locus_tag="VXF95_000301"
     CDS             56342..57382
                     /locus_tag="VXF95_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HEV1080904.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            complement(57503..58429)
                     /gene="cysK"
                     /locus_tag="VXF95_000302"
     CDS             complement(57503..58429)
                     /gene="cysK"
                     /locus_tag="VXF95_000302"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HEV1080905.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKPGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVYAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDSIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEFEV"
     gene            complement(58714..59349)
                     /locus_tag="VXF95_000303"
     CDS             complement(58714..59349)
                     /locus_tag="VXF95_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HEV1080906.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            59405..60703
                     /locus_tag="VXF95_000304"
     CDS             59405..60703
                     /locus_tag="VXF95_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1080907.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTL
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLSLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLEEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVIEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            60700..61362
                     /locus_tag="VXF95_000305"
     CDS             60700..61362
                     /locus_tag="VXF95_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HEV1080908.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVEVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            61442..61990
                     /gene="raiA"
                     /locus_tag="VXF95_000306"
     CDS             61442..61990
                     /gene="raiA"
                     /locus_tag="VXF95_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HEV1080909.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNVVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            62126..64099
                     /locus_tag="VXF95_000307"
     CDS             62126..64099
                     /locus_tag="VXF95_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HEV1080910.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTSLLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGRKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNIQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            64096..64548
                     /gene="rplI"
                     /locus_tag="VXF95_000308"
     CDS             64096..64548
                     /gene="rplI"
                     /locus_tag="VXF95_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HEV1080911.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            64592..65944
                     /gene="dnaB"
                     /locus_tag="VXF95_000309"
     CDS             64592..65944
                     /gene="dnaB"
                     /locus_tag="VXF95_000309"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HEV1080912.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            65946..66212
                     /locus_tag="VXF95_000310"
     CDS             65946..66212
                     /locus_tag="VXF95_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080913.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            66301..67647
                     /gene="cbpD"
                     /locus_tag="VXF95_000311"
     CDS             66301..67647
                     /gene="cbpD"
                     /locus_tag="VXF95_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HEV1080914.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDGGSVGNSQSSTSTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGHSVLSSTGGTHYFKTKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAVNTTVDGYRVNSDGERV"
     regulatory      67730..67832
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            67905..68195
                     /locus_tag="VXF95_000312"
     CDS             67905..68195
                     /locus_tag="VXF95_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HEV1080915.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAGQEADNVFANVKINVGEILSIDEKLEKYTETPH"
     gene            68158..68916
                     /locus_tag="VXF95_000313"
     CDS             68158..68916
                     /locus_tag="VXF95_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1080916.1"
                     /translation="MRNLRSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     KPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRS"
     gene            68955..69962
                     /locus_tag="VXF95_000314"
     CDS             68955..69962
                     /locus_tag="VXF95_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1080917.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            69962..70690
                     /locus_tag="VXF95_000315"
     CDS             69962..70690
                     /locus_tag="VXF95_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1080918.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            70809..71267
                     /locus_tag="VXF95_000316"
     CDS             70809..71267
                     /locus_tag="VXF95_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HEV1080919.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            71269..73701
                     /locus_tag="VXF95_000317"
     CDS             71269..73701
                     /locus_tag="VXF95_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1080920.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYEMDRLEEVALELTETDYSQDETFTELPFSRRLQVLFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKAKHVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            74022..74675
                     /gene="rr06"
                     /locus_tag="VXF95_000318"
     CDS             74022..74675
                     /gene="rr06"
                     /locus_tag="VXF95_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HEV1080921.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDLWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            74672..76012
                     /gene="hk06"
                     /locus_tag="VXF95_000319"
     CDS             74672..76012
                     /gene="hk06"
                     /locus_tag="VXF95_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HEV1080922.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDVYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGEVGKQINGMYEHLLKV
                     IHELESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIA
                     KSINKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIEN
                     QLTDATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQE
                     LEHLFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            76107..76634
                     /locus_tag="VXF95_000320"
     CDS             76107..76634
                     /locus_tag="VXF95_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HEV1080923.1"
                     /translation="MVLAIILVTFLIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     LAHIVFYLSCLVEAMVHKTMFDGMSMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYMTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            76713..78863
                     /gene="pspC"
                     /locus_tag="VXF95_000321"
     CDS             76713..78863
                     /gene="pspC"
                     /locus_tag="VXF95_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein PspC,
                     choline-binding form"
                     /protein_id="HEV1080924.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATSSNMAKTEHRKAAKQVVDEYIEKMLREIQLDRRKHTQNFAFNMKLSAIKTEYLY
                     GLKEKSEAELPSEVKAKLDAAFEQFKKDTLKLGEKVAEAEKKVAEAEKKAKAQKEEDR
                     RNYPTITYKTLDLEIAESDVEVKKAELELLKEEAKTRNKDTINQAKAKVESKQAEATR
                     LKKIKTDREQAETTRLENIKTDRKKAEEEAKVKAKPKKRTKRGALGEPATPDKKENDA
                     KSSDSSVGEETLPSPSLKPGKKVAEAEKKVEEAEKKAKDQKEEDRRNYPTITYKTLEL
                     DIAESDVEVKKAELELVKEEAKESRDKEKIKQAKAEVESKKAEATRLEKIKTDRKKAE
                     EEEAKRKAAEEDKVKEKPAEQPQPAPAPQPEKPTEEPENPAPAPKPEKPAEQPKAEKP
                     ADQQAEEDYARRSEEEYNRLTQQQPPKIEKPAPAPQPEQPAQPSTPKTGWKQENGMWY
                     FYNTDGSMATGWLQNNGSWYYLNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGS
                     WYYLNANGSMATGWLQYNGSWYYLNANGDMATGWFQYNGSWYYLNANGDMATGWLQYN
                     GSWYYLNSNGAMVTGWLQNNGSWYYLNANGDMATDWVKDGDTWYYLEASGAMKASQWF
                     KVSDKWYYVNGSGALAVNTTVDSYRVNTNGEWVN"
     gene            complement(79093..80073)
                     /gene="dusB"
                     /locus_tag="VXF95_000322"
     CDS             complement(79093..80073)
                     /gene="dusB"
                     /locus_tag="VXF95_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HEV1080925.1"
                     /translation="MTNLNTPFMIGNVEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLID
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(80060..80932)
                     /gene="hslO"
                     /locus_tag="VXF95_000323"
     CDS             complement(80060..80932)
                     /gene="hslO"
                     /locus_tag="VXF95_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HEV1080926.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGVEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            81097..82524
                     /locus_tag="VXF95_000324"
     CDS             81097..82524
                     /locus_tag="VXF95_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080927.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSVGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            82683..84191
                     /gene="glpK"
                     /locus_tag="VXF95_000325"
     CDS             82683..84191
                     /gene="glpK"
                     /locus_tag="VXF95_000325"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HEV1080928.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQVDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEVDD"
     gene            84233..86059
                     /gene="glpO"
                     /locus_tag="VXF95_000326"
     CDS             84233..86059
                     /gene="glpO"
                     /locus_tag="VXF95_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HEV1080929.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVKAALAQNDLAELKN"
     gene            86127..86831
                     /locus_tag="VXF95_000327"
     CDS             86127..86831
                     /locus_tag="VXF95_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HEV1080930.1"
                     /translation="MMSELFGEFLGTLILILLGNGVVAGVVLPKTKSNSAGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEVEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            87128..87331
                     /locus_tag="VXF95_000328"
     CDS             87128..87331
                     /locus_tag="VXF95_000328"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080931.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEGKKQELLNRLNK"
     gene            complement(87418..88005)
                     /locus_tag="VXF95_000329"
     CDS             complement(87418..88005)
                     /locus_tag="VXF95_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080932.1"
                     /translation="MFVFADDSLSANSKVVSGEAQFENGSSVRFGDTQVNILSDEVLE
                     VVNPDGSVDTIERRADGVYINGAFYMAYQKNEIDLNISFRSYDPNVWNYVNTIHGNKQ
                     ANTFANFMTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSPYPYYITS
                     TYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            89172..>90332
                     /gene="ltrA"
                     /locus_tag="VXF95_000330"
     CDS             89172..>90332
                     /gene="ltrA"
                     /locus_tag="VXF95_000330"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HEV1080933.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLRVEITKPNGGIRQLGIPTVMDRMIQQAIVQVISPICEP
                     HFSDTSYGFRPNRSCEKAIMKFLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRHKTLVGTPQGGNLSPLLSNVMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAAAKRVMYSASRFIEKRLGLKVNMTKAKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKLKLKKLTQRKWSIDLTRRIEQLNLSIRGWINYFSLGNMK
                     RIVASIDERLRTRLRVIIWKQWKKKSRRLWGLLKLGVPKWIADKVSGWGDHYQ"
BASE COUNT        28576 a        15665 c        18418 g        27673 t
ORIGIN      
        1 tttcgtcatt catttttgac tttacttcat cataggatag tgcatgagat tcctcttcta
       61 ctgcttcagg catctttcct gtttcgtaaa gagctttaat ttgtgtacta tccaatgttt
      121 cgtatttcaa taatgcttct gcaattaact tgtgagtttc acgatttgac tgaataattt
      181 cagcagcttt atttcgtgcc tcatttaata atgaacgaac ctcttcatca atttcataag
      241 ctgtttgttc tgaaattgat ttttgaggac tctgtgcacc aagcatagca tggtttcctt
      301 catattgtac tgggccaagt ttttcactca taccgtactc tgtaaccatt gcacgtgcca
      361 tttgtgtcgc ttgttcaaag tcgtttgaag ctcctgtagt ttggacatta aagataattt
      421 cttcagctac acgtccaccc attaagccag ccaattgctc tttcatatct tctttagata
      481 gaagcatttg atcctcttta ggaagtgcaa tcatgtatcc gcctgcacgg ccgcgtggta
      541 caattgtaac cttatggaca acgcgagcat tcgacaagac tagaccaaca atggtatgtc
      601 ctgcctcatg gtaagcaacc aattctcgtt ctttttgtga aactgtctta tctttcttag
      661 aaggtccagc aataactcta tcttctgctt catcaatatc tgaagcatca attatcgatt
      721 tattgcgacg agcagcaact aaagctgctt cattcaagac attctctaaa tcagcaccaa
      781 caaagcctgg agtttgttga gccactaatt tcaaatcaac atcttctgct aaaggcttgt
      841 tcttagcgtg aactttcaag attgcttcac gacctttaac atcaggacgg ccaaccaata
      901 cttttctatc aaaacgtcct ggacgcaaaa gggcaggatc aagtacatct gaacggtttg
      961 tcgcagcgat gacgataatc ccttcatttc cctcaaaacc atccatctca atcaaaagtt
     1021 ggttcaaggt ttgttcacgt tcgtcattac ctccgccgag accgactcca cgttgacgtc
     1081 caacagcatc aatttcatcg ataaagatga tagctggtgc tgcttttttg gcatcctcaa
     1141 aaagagagcg aacacgacta gctccaactc cgacaaacat ttctacaaag tcagaacctg
     1201 agatactaaa gaatggaaca cctgcttctc cagcgactgc cttagcaagc aaagtcttac
     1261 ctgtccccgg aggtccctcc aaaagaacac ctgctggaat acgggctcca agttttgtga
     1321 atcgttttgg atcttttaag aactcaacaa cttcaactag ttcttgtttt tcttcctcag
     1381 ctccagcaac atctgaaaat cttactttaa tatcttcttt atttgctgct ttagccttac
     1441 tacgtccaaa actcattgga ttacggccat tgcctcctcc catatttccc atcatagaga
     1501 ataggaagaa gaatagaatt ccaaatggca caatggatac gagtagatta atccatatac
     1561 cacttgaact ttcatgctta acagttactt ctgctttatg gtcagtagca agtttttgca
     1621 attctgatac ggtagtatct gcaggaagaa tagtgctggt aaatttctct accttagtaa
     1681 cagatggcgt gaaaaactga atacctgttc cttctttact tgttttagga tttttataga
     1741 caccagaaac ttcgataaca ctaccatttg gttggtaagt taattctttt acattaccat
     1801 cggtaatttc ttgtaccaac tcagtatagt tgatttgctg acttcctcct gagttattcc
     1861 cagaatagaa atactggaat cctgtcacaa ggaaaaagat aaataataac catagaaaag
     1921 gatttttaat taaaccatta ttttgttttt tcattaaaga ttattctttc taatttgaat
     1981 acacttcctc tttcaatact ccaatataag gaagattacg ataattttct ttgtagtcta
     2041 aaccataacc tactacaaac tcatttggga tagtaaagca ggtatagtct gcctcaattt
     2101 ctacaacacg tccttctggt ttatccaaca aggttgcaat tttaacagaa gctgcttctc
     2161 ttgctttaaa catatctcgc aaattcttca aagtttgacc tgtatcaatg atatcttcta
     2221 caaatagaac atgtcttcct ttgatatctt gagtcacatc ttgtttaata ttgataacac
     2281 cactacttgc tgttccacca tggtagctag aaaccatcat gaagtccatt tcaatatgtg
     2341 tatcaatatg tttgaccaat tcagccataa aaggaataga tccttttaaa atcccaacta
     2401 agattggatt ttttcctgca taatctttag ttaattgagc acctagtttt ttagctgctt
     2461 ctgtaatttc atcgtgtgaa acgaggactt ttttaatatc gttttctaac attttttacc
     2521 tatctatttt ttctatataa agtacagtgt tcattatatc atttttcgtt tttttactca
     2581 aattattggt cgcaattccc aaaattgaga caatttcacc aaattgctca ataataagag
     2641 cagagtttct cttttccata gggattttca aatcaataaa taaacgtctg agtttttttc
     2701 tatgcccatt ttgaatcaaa acatctcctg tttttcgatg acgaatgtgt atggatgttt
     2761 cacgtgaaac aggtatttgt tgaattgatt caccttctaa tggaagtcca aaggaaaata
     2821 aatatccttg ataagctacc tgattttgat agtgtaacac aagttcatct tccttttcat
     2881 cagcctgcgg actgatttta caaatctgaa actgttggta ctcttttatc aattcatagc
     2941 catttttaat cggatgacga tactggcttt tagattttaa aatctgctga acttcagcaa
     3001 actgagcttt tgtaagattc aaatctggaa aacgattcag ataagtttga agtaaaactc
     3061 tttgtgtaga ctcagagtaa gaaaataact gctgtaaatc ttccacatta atattgttag
     3121 ataattcagc tattgccaaa tcataatcta aaatttcatt gccaatgcct aagattgcat
     3181 ccctaaatcg aggattttct ttttccaatt ctggtaagta agagtttcga atacgatttc
     3241 gaaaataatg attctcctga tttgatgtat cttcaaagtg aaaaattgat ggaaagtctt
     3301 ttttctgaaa atgcaagaag ggacgaatga tttctatctc tccgactact tgcttctcct
     3361 taattcctga tagatagcgc aagcgagttc ctcgaatcaa gcgcatcaaa atcgtttcca
     3421 cctgatcatc agcatggtgg gcagtgacta aagctgtcgc acctgtcttt ttcataacct
     3481 cttgaaaaaa atcataacga aaatttcgtg cacgcgcttc tgaaaattct cctgaaaaat
     3541 tgctgatata aataggaagc tctgcttcag cagccaactt ccttaattcc ttttcttccc
     3601 aatctgattc aattctctgc ttatgattca catgagccag aatcaattca atctctaact
     3661 ctttttgata agtagacaat accttaaata gaaacataga atctaatcca ccagaaagag
     3721 ctagaaccgc cttagcatgc tttttgaaat atcccttctt gagaaaatga tttaaaaaat
     3781 ctggttccct cattttagaa cctcataaac atccttggct atcttagaaa tcgtatcata
     3841 atcagaattc ttagtgaaaa tagaaagaat aaatggagaa tctgcataga caacacccgt
     3901 atcatgctta aattcatccg catctccaat tttatgagct actttaacag aaacaccttt
     3961 ggcaattcgc tgactatcaa aatctgtttt agtcaaagac tctagcacaa atccattttg
     4021 attataaata gcttccataa acttcccggc catcttagaa gaaatcaatt tttcttttgg
     4081 atcccaatca tctcccataa tggcagacat tttggatttg aatgtggcat cagattggtt
     4141 tgaaatgtaa tatcccaata gattatgagc tacattatca gattcttttg atactttcgt
     4201 aattaaatcc tttaaagaat attctttatt atcttctttt ttaggaagac taccacttcc
     4261 ctctggttta taagaacctg gaaaatcatt gactgcagat acgtatttta cagtcgtatc
     4321 taactgataa agaccctcat ttattttttc ttgcgtataa tagagatagg agagtttcaa
     4381 aacgctggct gcatacatct tttcatcttg attgatacca gcttcttttc cagtagtcag
     4441 ttgcttaaca taaatagaga aagaatcttt ctgatatttt tcagataaca tttcttgaac
     4501 tttactcatc cgattatctt cttcagaagt tgattcttta gctacccatc cagcctgatc
     4561 aatatgtaga aattctcttc cttctacaaa catggtcttg tcgattgata cttgcgaata
     4621 agctgataag gatgatttca cttcttttaa atcataagga ctattgtaca gtttaaagtc
     4681 agattctaac catacttttt ttattgttgg agttacctct gattgatcat ataaaaatcg
     4741 tttgtccgca gctataaatt gatgatttga tagcttaaat actggaatcc cttgtttatt
     4801 taagcgccac tcggttattt gaaaacttgt tttgggagtc aattccccag attccactac
     4861 taaatcttca ttcgcataaa caggaacctc tccataaacc atgggagaac ttaatttttc
     4921 tctaaaataa ataccaaagt cagattgtga aaggtaataa atttctttcg aagtatagac
     4981 gacttctttt tctgtgctaa cgacttttga aatggtcaaa aaacttggta gcaacaaaat
     5041 aattaagaat ttacgcattc ttcctttcct tttcttcttg taaacgcaat aattgatttt
     5101 tatcagccaa ttcttccaac ttttcatctg acaaacccaa aaattgctct attacgtcta
     5161 ataaattttc cattttatca cctttgaagc aagtcaggaa tcgtataaac tttttccctc
     5221 gacttagaat aatagtactt cgctcgtgta tatttagcag cataatcttc atctttcaac
     5281 ttggtagcaa atgctgtctc cttatccttt tcatcactca aagtttgata ctgagtttgc
     5341 aagtctgcta attgctgacg tctttggagt aattgctgat aactctgcgc taaattaaaa
     5401 gttggcaaga taaataatag cataatcaaa atcaataccc ctcccataaa acgattccgt
     5461 ttttgtcgtt ctttcatcag gtagcgacga cgttggtatt cattttgaat aaaagaatta
     5521 ttcaattgta caatattttt agacattttc ttctacccgt gtttcactga taatttcata
     5581 cattcctgct gcatcttctt tttttgtact atctttcatc tctagtactt ttacaagcag
     5641 caacttattg ccaaagcgaa tttcaacttg gtcattaact ttcaagtccg ttgaactttt
     5701 ggccaagatt ccattaacct tgattctacc tttatctgct acttcctttg cgactgtacg
     5761 acgcttgata attcgcgata cttttaaata tttatctaat ctcatcctta ttacctcaat
     5821 ttattattgt accattttta tctattttat agaagaaaaa tatcaaatgg aattttcttc
     5881 cttagactct tttatctcta ataaactttc tccaaaaatc agcagacctt ctaaaatttc
     5941 ataatctttc ttattttgaa catcaaatac aagctccatt aattccttat tctcagcgat
     6001 gcctgctttt aagttcgtta cggataaagc tttaaaataa tcttgagcta aaaacagtcg
     6061 ttgagtgact ttttcaaatt gaattgtaat tttattatct tttctttcca cacgttgaac
     6121 aaagaccttg tccaagtatg atttgaccaa accaatctct aaaagatagg ctactacatc
     6181 tgggtattct ccaaaacggt ctatcaactc ctcttgtaac tcttcataat tgacacggtt
     6241 gtcaatttga cgaattttct tgtaaatttc aatcttatgt cgttgatcag aaatataagt
     6301 atcaggaaga taggcatcaa tttgcaaaat caactcagca ttccctttgg ttcttgtgtt
     6361 agcgttagca ttaccgtttc gtttagcaat agcttcctct aataactgcg aatacaattc
     6421 aaaaccaaca gaatcaatga aaccagactg ggattttcct aaaagatttc ctgctccacg
     6481 aatcgaaaga tctcgcattg caatcttaaa gccagagccc aattctgtaa atcctttaat
     6541 cgcttctaat ctcttttcag agacttcact gattgatttt tctggacgat acatgagata
     6601 agcataagca atacgattac tacgaccgac tcttcctctt aactgatata aggttgacaa
     6661 gcccatatgg tccgcatttt caataaataa agtattagca tttggaatgt ccacccctgt
     6721 ctcaataata gtagtcgtca ccaagatatc gtattgtccc tcaataaagt ctaatagagt
     6781 attttccaac tggacttcac tcattcgacc atgaacatat ccaatcgaag cctccggaat
     6841 caactcctgt aattctgaaa ccttctgaac aattgtgtca actttgttgt aaagataata
     6901 aacttgacct ccacgctcca tttcacgcaa gacagcatca cgaatgacac tatcattctt
     6961 ttccaaaaca taggtctgaa caggatagcg attagtcggc ggagtttcaa taacagataa
     7021 atctctgatt cccagcatag acatatggag ggtacgaggg attggcgtag cggtcaaggt
     7081 taggacatcc acttgtttct tcagttcttt caaagtttcc ttatgcttga caccaaatcg
     7141 ctgttcctca tcaataatca tcaagcccaa atcagcaaac acaacatctt ttgacaaaac
     7201 acgatgtgtt ccaatcaaaa tatcgacttg accgtttttc aatttttcaa gtgttgcagt
     7261 ctgctctttt ttacttctaa agcgactcaa cacatcaata ttaactgcaa aattttggaa
     7321 tcgttcctta aaattcgtat agtgctgttg cgctaaaacc gtcgtcggaa ctagaatgac
     7381 aacctgtttg tgatcattga ctgctttaaa ggctgcacgc atagcaactt cagtctttcc
     7441 aaaaccaaca tccccaacta aaagtcgatc cattggctga gaagcctgca tatccctctt
     7501 gatttcctca atactacgaa gttgatcatc cgtttcaaca taagggaaag catcatcaaa
     7561 ggcatcttga tcatcatcat cagctgagaa agcaaaaccc ttcaactgac tacgttcaga
     7621 gtagagtttg attaaatcat cagctatatc ctctacctgg ttcttaacct tttgcttggc
     7681 ctttttaaaa tgaccgtcat ttaatttatt gagttttgga gctttaccat cacttgaaat
     7741 atatttggac agtagatgaa tctgttccac gggaatagaa atttgatcac cattttggta
     7801 ttggacactg acataatcac gatgaattcc cttgatttca atggtttcaa ttcctagata
     7861 ttgaccaatc ccatggatat gatggacaac atagtcccct ttttcaagtt cattgtaatc
     7921 ttttaatctc tctgcatttg aaacatgttg tcttcgaaaa cgacgcttta atttcttttg
     7981 aaaaatctca tgttcagtta tcaataaaat cttttcatct acaaaatgaa aaccatgtct
     8041 gagattaccc tctattaagt ttacagattc tttacagata tttgtcttat ctctagaatc
     8101 caatttaatc tgatattcct ctaacatatc ctccaatgtt ttacttccca ttgaattgct
     8161 agactgcaga ataatggtgt aatccatttt tttatatcgt tcaatttctt cttttagaaa
     8221 agaaaactga ttgaaaaatt cctgcatagg atattgattg aattgataaa ttttgtcaaa
     8281 tttgagattt cctaaaccct tttgaagatt agaaaaaaag gtcactggac tttgtttttt
     8341 atagatttgt tcaatatcag aaaaatactg catatcagaa aatgctttac tattctgtaa
     8401 ttcttctgta aagtactgcg ctaattctct ttcaaagact tcatactgat tcatcaattt
     8461 ttgataatca tcaaagaata ttggagtatc tttttcaata taatcaaaga cagtccatgt
     8521 cttatcatag cacaaagata aaaacttccg agagtctgca tgactttgtt tttggtgaaa
     8581 acttgaaaga atttcttcta ggtatgattt caaaataggt gataaagttt ttgaaatttg
     8641 tttttctaaa gctgactgtc ctcgttgata atccttttct ctcaaaagca tatcactagc
     8701 tggaaagata gtgagttctg tcttattttc tttcgataat tgtgtttcta cttcaaatga
     8761 cctgatacca tcaatttcat caccaaaaaa ctcaattcga caaggttcta actgggatat
     8821 ttcaaaaata tctaaaatat ctcctcgaag actaaattcg ccctgagttt gtacttgagt
     8881 aacttttcga tagccatttt cctttaactg atggataaac gcgtgttgat catattcttc
     8941 accaactgag atttttacaa tactatcttt gaatgcattg ggagacggta aaatcaatcg
     9001 acttgctgcg atattacaaa ctaaaatccc tttcttagat gaatcagtca aaaaacgcaa
     9061 ggcttcaacc cgtgaaataa ttttttcctg tgaagacatc aaaaactcca ccataggagc
     9121 atcatctacc aaaaatggat agacgagttc ctcacccaag atagatataa gatcactaac
     9181 aagtccttct gcttctccat aagttgacat caataacaca atcctatctt ctttttctaa
     9241 actgcttgca attgcaagag ccttagtaga tgttgataaa ccaagtatta gttgtctttt
     9301 cttatctgtt aaattttgat gccatttttt aatctgatca ttttctgaga ataaatctaa
     9361 taaggtcacc atttatccgt tatacctctg cattgttttc tcaaaatttt tctcttgtaa
     9421 atagtagttt acagaatcgt caactttgtc aacagactgt aaaataccga tatactcatc
     9481 cctgtcaaac ttactcaaaa catgatgaac aactgacata ccatttttag gtcttccaat
     9541 tccaatctta acacggttaa agacctgagt tcctatatgt tgaataatag acttgatacc
     9601 attatgacca cctgctgagc cttttgctct taaacgaatt ttcccaactt ccatgtcaag
     9661 atcatcgtaa atgataagta aatcgtcaat atccaaacca tagtaagtta ataaagcatg
     9721 aactgctttt ccactttcat tcataaaggt cgttggttta accagataaa ttttttctcc
     9781 atttaggaaa aaggatgcta ggtcagcttg aaatatctta tcgtgtgtaa aagtgacatt
     9841 ctgtttcttc gctagttgat caatcaacat aaaaccaaca ttgtgttttg tttcaaaata
     9901 tttatcccct ggatttccca agcctacaag taatttggtc atttattttt cctttcaaaa
     9961 gccaaaaggg ttggaatttt tttccaacct aattgacacc atttattaat ttttagacat
    10021 taaagcggaa ttccatgata tcgccatctt gaacgatata ttcttttcct tcttcacgca
    10081 agcgtccagc ttcttttacg gccttttcag atccgtattt cactagatct tcatatgaca
    10141 tggttactgc acgaataaag cctttttcaa agtctgagtg gataatacca gctgcttgag
    10201 gagccttcat accacgtttg aaagtccaag cgcgaacttc tttttcacca gctgtaaagt
    10261 aagttcccaa tccaagcaag tggtaagctg cacgcgtcaa cttatctaca cctgattctg
    10321 tcaaaccaat ggcttcaaga aactcttttt tatcttcatc atccaattca gaaatttctt
    10381 cctcagcacg cgcagaaata acgactactt cagcattttc tgtcgctgca aattcacgaa
    10441 tttgtttgac atagtcgata gagtcaggtt ctgaaaccac atcctcgtcc acattagcta
    10501 cataaagaac tggtttagtc gtcaaaagga aaagaccttt gacaaccttt tgttcctcat
    10561 ctgtaaattc aatggtacga gctgatttcc cgtcttctag gactggttta atcttttgaa
    10621 gaacattaaa ttctgctact gattctttat ctttttgcgt acgtgccatc ttttctacac
    10681 gcgcatatcg tttgttcact gattctaagt cagcaagaat taattccaga ttaattgtat
    10741 caatatctgc aagtggatct acaaaggcgt cttcacgtcc ttgctcgcgc atcacatttt
    10801 catcatcaaa agcacgaact acgtgaacaa tcgcatctac ttcacgaata ttggccaaga
    10861 atttattccc tagcccttct ccttttgaag ctccttttac aatccctgca atatccgtaa
    10921 attcaaatgt tgtgggaact gtctttttag gagttatcat ttcagttagt ttttgtaggc
    10981 gttcatctgg aacttccacc attccaacat ttggatcaat agtcgcaaat gggtagtttg
    11041 ctgcctctgc tcctgctttt gtaattgcat taaatagtgt tgatttacca acgtttggca
    11101 aaccaacgat acctgctgtc aaagccatat ttctcattct ccgttttcat ttcaatccct
    11161 aatattataa cacaaaaagg gaaaacttgc taaaattcct tgatatagct atttcccata
    11221 actgaaataa taattttatg gactttttta ggaacttttt aatttttcaa tggctttttc
    11281 ataaaatgaa gtagcatttt tctgattgtc tttggatagg tggctataaa tatccatggt
    11341 catagaaagt tttgcatgac cgagccgtgt ttgtatctct ttgtaaggta gtccagcatt
    11401 gagcaagata ctagcatgag tgtggcggaa ggcgtggaac gtaaaacgag ggcatccagc
    11461 acgttccaaa tgttttacta acctgaaact aagcattcta gcgtctatat gcttatcaaa
    11521 gctattagag aatactttct cataggtcaa ccccatttct ttccctattt gggattgtct
    11581 tgctttatag agccgtagca tgagcaccgt cttattatcc aagtcaatta ccctaatact
    11641 tgatttagtc ttagggacag tgatttcttt gataatattt aacgttttat ttacgtctag
    11701 tgtgccgttt tttaggtcaa tatcagacca tttgagggct aaacactcac gaatacgcaa
    11761 accagtcgct aaaagcgtct tatatagcac cgtatcgtag aaatttttgt aagtgtttgg
    11821 cagctgctcc aggtaagtca agaatttttt taagttatca tcatccagat atttcagttt
    11881 ttgcccttct ttttccttac gacgtggcac gataacatca cgggcagggt taaaggggat
    11941 agcttgcaaa gatacggcat atttaagtat gcgtttgttt agagagtgaa ggagcggata
    12001 ttcttggaat cctttgccta gttgattata gtcttttgcc cattgattga cttgcttttg
    12061 aatgattggg ggcgtcagtt tatccagcct ataatttccg aaagctggaa gtagatattt
    12121 atctattttg aatttggtac ccattaaggt cgatttttta accgtatggc agtacgtttc
    12181 tagccaattc tccaccagtt cggcgtaagt ctttatctca actgctttat atactgtagc
    12241 ccctcctttt tcaaagtcta tttgagcctg tagtgctttg gctttgagtt ctctcttggt
    12301 tcgccctgat atagtcgtct tgactttctt acctgttacg gtatcgatac caaggtagac
    12361 gctagagcga tagactgtag aaccgtcttt tttggtgtat tctgttattt tcatggtttt
    12421 actccttttt ccatcagcag gcaagcaatt agaaaaggtt ttgagtttat accatgcgag
    12481 ggactgcgag aatgccccta ttttcgattt taattagcca ggcggtaaat aataccagaa
    12541 taggaaataa ggcggatatg ggatttgtat gggcgttttt acatatcatc aaagagtgaa
    12601 agttggttat tatccggttg ctttttaagt ttcttttgtt tgttttttag gtcttggcaa
    12661 ccacactttt ttcggagtct tcacataaat gttggaaaaa gtcggatttt caagaatact
    12721 ggaaaaaaac aattttcttc attttctgag tccctaaaaa gcgatggggt aaacaattcc
    12781 aatcccgttt ctattagttc ttaatggttg gaaaactaac atttctaaca ccctaaaaag
    12841 gagaagggtt tagacaaggt cagaggactt gctgaagccc gagaaagcac gcgcttcagg
    12901 attgttgaac attgtggcgc gtggtaggct ataggtcgca ttttcggcac tttcggcagc
    12961 cctaaaagaa aaatagtagc gatgcgcttc atgtttgttg caattttgcc caattttacg
    13021 ctttagtctg taaatcggct ttctattctt caattttccc cgtttttgca caatagacca
    13081 tgaaaaaagg gggtattcga tgaggtggta tatttttgtt tatgaattat gggtaataac
    13141 atctaaagct ccaataatct tttgagcatt ttcaatagct tctttgtatt ctttagatgt
    13201 gtttttaaca ggttttttaa ttaaatctat aaaaacaact ggtttagtaa aatcgttaga
    13261 tgttattcgg attgtcatat tcaaaatctt ggtagttgct tttcttttag cgacgattcc
    13321 gccagctacg gctcctatta caccaaatac cgccccagct actaaagctt gtccaacacc
    13381 gccggaaaca acagactgat cgtttataac taattcgtaa gatactaaat catcgaagga
    13441 gtaccagtcg gtatcatttt tatctttttt aattaaagat ggaatcaaag acaaaccgcc
    13501 tgtcccaagc gctaaggtag tttttccaac aactttagca gttccgccaa tcagacctga
    13561 tgaacctttt gcttttcttg ctccgtgtat tctatatgta cgatgatttt tgtctatttc
    13621 aagaggtccg actttatcag tacgtttact tcttacagta gaaggtctag acgatggagt
    13681 tgctactttt tggggagttg ttttaagcga ggcattgatt gagtatccgc aattcggaca
    13741 aaacttgcaa ccgacaacag aatttccgca ttcaggacaa aatttcataa tttttttact
    13801 ccttttttac ttttctctat aaatgcccac gacttcgccg atggtgcgta tatcgttgct
    13861 ttcgtctagt tgaatatcag cacattcagg gttaaggctt tctaaatacc cttgacgcag
    13921 tttcttgacg tagttagcgc cgtctacttg gaagataccg atagtgttat agtcaacttg
    13981 aggtgtattc ttgataaata ggtagtcgcc attctttatc tttggctcca tggagttgcc
    14041 gacgacataa gcgatagcgt catagtcgtc tgggatttca tcagtataaa agcatttttc
    14101 tatgtttagg ttatcgtctt gggttatccc gtttccggcg gttacaactc cgataacagg
    14161 gagcgtcttg ctttctctgt agtcgtccag actgataatg ttttctgata ctatgttttc
    14221 gtttttctgc tccagcagct gctttttaag ataagtcaag gctttttctt gtcttggtgg
    14281 agtgagttgg tcatagatgg attggatggg ggaagtggta ggtgtttctg cgtttttatt
    14341 ttctactaag tcagactttg aaacgttgaa aaaattagcc agcatttcga ttttatctat
    14401 acgtgggtaa gttttagcat ttacccaatc gttgacggtt gtatacttaa aatctaatgc
    14461 aatagctaat tgacgagggt ttaaaccttt tgcacttaaa agtcttttga tattgtccgc
    14521 cattatttgc ttatttccta atgacatggt gcaaccgcct ttctataatt cataatttaa
    14581 ttatacggtt aaaacgtaga aaaagcaagg gaaacaaaaa aaaagaaaat aaaatcaaaa
    14641 aaagtgttga caagttatcg gttttaccgt atactgtcat tgtatccgat ttaaacggat
    14701 atccaaaaga aaggagtgag ggctatttgc gtcttacatt gaaagcgttg cgggctaata
    14761 gcaacatgaa acaatcagag gtagcacaaa aattaggaat ttctacaact acttggagta
    14821 agtgggaaaa tggaaaaagt tttcctgatg ttgcccaagt aaaagagatt gaaaaacttt
    14881 tcggtgttgc ttatgacgac attatttttt taagctaata tccgatttaa acggatatag
    14941 aaaggagcga cccaatcgca atactatatt acatctacaa gatactccac tggtgcttta
    15001 ccactgggga ttgaccttct cggaagaaat atccgaccta gaacataaag gagaaaacaa
    15061 catgaacaat aaacaagtat atcaagcaca aacaactgac cacggtatcg ctagagcatt
    15121 aggcgaagaa attcgtatga tcacagacgt tgaagaaaca acttacaatg gacacggtga
    15181 aatcattgtt gagtacacca gtgacgttgc attgacaaaa ctatttgacc gtattaaagc
    15241 actttacgaa aaaggcgaaa gctacgaaac aaaaccattt ttacatttta aagtattgga
    15301 agatgatatt gaaccaagcc caaatggagt ttttactgct aaagaggtgg cagagttttt
    15361 aggaatttga ttaacaataa ggagcaaacc aatggaacta gtctacatgg acggcaagaa
    15421 agagccgtat acactgagca gtattgtggc agagtgtgca gaagttaagc acagacattt
    15481 aaagattttg ctgaataagc acagagagga ctttgagagc ttcggaaagg tgcaatttaa
    15541 aatttcacct tcagagagtg ggcaaaatgt acgagattat attttgaacg agcaacaagc
    15601 tactttgtta atcacttact tacgaaatac agaaccagtt cgtaaattca aaatgaacct
    15661 ggtcaaagct ttctttgaaa tgcgtgagga gctttctaag tttcgtatgc agagggcgct
    15721 agaaaagcca aaaagaaaaa ccttgcatga cagtattgag aactgggaac aagcacccaa
    15781 gcacgcgcat agcactatga acaacctgct actaaaagca gtaaccgaca ggaacgctaa
    15841 gcagttaagg gaagaacgtg gaggctataa tggcatcgat agcttgacca gtgacgagct
    15901 ggagcaatat caagcctttg aagacatggt aatagccatg attggcttga atatgagtta
    15961 tcaggaaatc aaggctatgg cattcagaaa taaaaaaaca cgccaaagaa gcgcgtgatt
    16021 gcaacaaaaa aggcttagca ataaccacac cgcaaagcct ttcacactaa gactaaaacg
    16081 aatttaacaa aaagcaggca agctattatt aaagaggttt tagtaagatt tatacctaga
    16141 ttatagcata atacagcggt ttccgctagt acattgaaaa taaaataagg tacgctggga
    16201 agattttaat ttttttcggt ttaggggttg acatttaaga cgacaagaat tataataatt
    16261 tatgtcgtca agaaaggagg caatccgatg actgacaaaa taaagaaagt aggacgtccg
    16321 aagggagaaa actctaatac cgtaaaatta acagtcagag ttagcgaaca gctaaatagt
    16381 aagctggaag agtacggtaa aaagaatggt ttgacaaaac ctgaaacctt gagaaaagcc
    16441 tttgaaaatc ttactaaata aaaaatacct tgcaacttgt caaacgccaa tccgagaagt
    16501 tgcaaagtat ccgcccccac gaatgaggta cgtaaatatc ttatcatgcg tactcttatt
    16561 tgtcaaacat agaaatagag tgcgcttttt gcgtacccaa aaatgaggta aagaatggga
    16621 aaacaagtat ttacacaaga aatactaaga aacatacaag aagaaaatgg aatcatcaca
    16681 gtagacttaa tactagacgc tttaccaact tggtcagaaa aagccatcaa gggacgttta
    16741 tcaaattggc gttaccgtaa agttattgac tacagggtag aagatgggga atttagtgag
    16801 attttcctac taagaagcaa gcaggagata aaagaagagg tcagtgccgg tcaacgtttg
    16861 aaaatggatt tatattttag acaggtttta gccttaactg gaatcattga atcaaacacc
    16921 agcaaggaca acgacaagac caaggcgatt gaattgcaac agaaagcaat gagagcaata
    16981 ccagacgaca tttacaaaga gttgtcagag atttatgagt aaataacaaa actaagaaaa
    17041 actaagaaaa ccgaagtgca ggcaagcaat tagaaaaggt tttgaaaagc atagagcgcc
    17101 aactctttaa actggtactt tctcacgctt tcaatttggc gagtctgagc gtgaggctag
    17161 tacttacaag aaaaaaactg tataagtaaa aagccccacg ctcagaagtt tggcgaccga
    17221 gagcgtgagg catgtggcaa gaaaaactgt ataagaaaca accattcaaa atccccacac
    17281 tcgccatcgc tcaactttga gtgtgaggat atcctggata gtaaaaggca ttaaaaagcc
    17341 cttagggcaa ctacacaaca tagaaacaga ggtacaagta tggaagaaac aacatacgat
    17401 attatcgcta aaagcttgga tagaattagt atggaattac accaagctga cgaaaataac
    17461 gattttctag aatatgggtt ttatcaggac aattaaaagg ccaacggagg aaaatatgat
    17521 agcagatcaa ttaaaagcta tttcaacaaa tttagaagaa atacaagaaa ttcttgtagg
    17581 agatggaact gcattagcta aaagagaaat cagcagggta ttgaacgact tggacgatgt
    17641 ttataatgaa ctaactagca cagaataccg tgaacaacag gaaacactta aggaacagac
    17701 ggaaaggatg aaacagagag tagttgctga agtaatagga ggactagaag aacgagaaga
    17761 gtcttattac agaaattatt ggggtgatac taagtttata aagctacttt ccaactttga
    17821 tggatttctt ttcttaaaca cttacctagc tgaaataact aaagaaaata cctacccaat
    17881 ggaacaaagt caattattga attatgtttg ggaagtcata gcggttgata tcgcaaagaa
    17941 aaaacgagga aaaaagaacg ttttggattc atggacagat tcatccttat atactcgtgg
    18001 aatgatgatt gattaggagg caatgcaatg acactagacc taggcaaaat gacacaagca
    18061 gaatttgatg aagtaatggc tgacatcaag gcaagaaatc caaacctatt acagttcatc
    18121 actgattttt tagatagaaa ggtaacaccc ggagaggtgg acgactagtt gaatatggag
    18181 cgagctgaac aagtggaata tattaagaat tatcaagcga gggcataaca tgaatgaact
    18241 agatataagt aacacacagg ctgctgtctt aatcgtgatt ttgattggtt tactgcttta
    18301 tttaaaccac cgagaccgca aaaaaagcgc ccaaattgag cgagaaaacc aacagacgat
    18361 aaaaacacct agcgaggatt taaaccctga atatgggcga tatatccagc ttgcaggagt
    18421 caacgtatgg ggagggatgg aatgagttac atagtgaaga tataccttga tagtgaaaaa
    18481 ataccagatg aaccttattt tactaaagag atttttctag ctacgtgtat gggcaatgca
    18541 acaaagttag ctgtaactat gggcttgttg acaaaacaag tgttggattt agaaactaag
    18601 acagctatct tgaaagccct tgatacaatc atagagactc aaaaagctat tttgcaaggg
    18661 gtagcgagcg gacaaataac ctttgtaaat aaaagtaaaa gagaggagga actggatgag
    18721 cctatcagag aacgataaac gagtattaag attaatcaag gtaggggctg agaactccat
    18781 aacagggtca gaaattagcc tgacaaccaa gctaacagaa agaactgtac gtgacattat
    18841 caagcgtcta gtagttaagc acaacatccc tattgtaggg gttagatgtg gcgtttttag
    18901 tgggtacttt attccagcga ataaaggcga gttactagat ggcgctaagg ctttttacaa
    18961 ccaagtacag gaggagagca agcgcctagc ggtgttgatg aatagcgacc tagaaagcta
    19021 caaagaaacc ttgaaggagg tgggcggata tgtttagcct aagccgagaa agcgagcaag
    19081 acctagcgca tggcattctg gaggtagtgg aaagatacct ggaagcgcgt gagaaagtac
    19141 cgccaagatt gaccaagtta ataaatagta gttgaactca aagaggaatt gaaaattagt
    19201 gacaacacgc tgaataagtg ggaaagtcag ggtttaagac gctatcaacc gccggacgat
    19261 ggttcaagaa tgatttacta tttagtaact gacatctgga agtttctggg ggtggatgaa
    19321 tgacaattta cgaggctaga ggtttccaga gtaatcttgt ctatccattt gataagattg
    19381 agccgttcca gtacattgaa cgctttaagc ctttggtagt ccctgaaagt gctgatacgg
    19441 aggaatacaa aagaacccag gcgccatatt gtttaagtgg taaggttatg ccggagaaaa
    19501 acgggagtta caaacgaaac aactccagtc taatctatcg ggatttgatt ttccttgatt
    19561 atgacgatat acaggggacg actgaggact tcatagaagc cgtttctagc gctttgtttg
    19621 gctactctta tatcttatac ccgactatca aacatagcat agaaaagccc cgttttcgcc
    19681 ttgtggtgaa atctaacaac gtgatgaacg aggcaaccta taagcaggta gtaaaagaga
    19741 ttgctgacaa gattgggcta ccctttgaca tggccagttt aacctggtca caactccaag
    19801 ggctaccagt aacaacaggc gacccagcaa cttatcaaaa gattgtagag catggacttg
    19861 attatccagt ccccaaggtt gaaccaagag cgaagcaagg aactactgag cgttataaac
    19921 ctagagtaag tggccagagg tcaatgacta tgaggattat tgacacgctt ttcaacggat
    19981 ttggagacga aggagggcgc aacgtagcgc tgacacgctt tgtgggatta ctcttcaata
    20041 agtgggttga ttgtgaccta gagacagctt atgaactgac aaagatagcc aatagcgtga
    20101 cggttgaacc attgcctatt gaggagctag accgtacttt tagcagtatt gcacgggctg
    20161 aatatagaaa gagaggttag aaccatagaa ctagaagaat tagcaaacct aaaaagtgaa
    20221 atcttggagg tcagagagca agaacaacct cctagaacga tgtgggaact ttatagtagg
    20281 atttgggagc ttggggatca atggcgtaag gaaaactcct atatcgtcaa tgaaggaaag
    20341 aaaaacgaaa gggtagaaat cccacgacca agtgttgcaa tcgtagccaa agcgttacag
    20401 gaaatttgcc attttacctt tataggtgag ggggttataa gtgatattag taagttatat
    20461 ctttaccatt tggatttagg ccattatgta tcaagtaacg acattttccg aaaattgctt
    20521 ttaaaatatg actcacgttt gacttctaac aagttctttt tagaacttat ctcctatatc
    20581 cgtacagaaa ctaagatgaa accaccgctg gacgattatc gatatattcc agtagctaat
    20641 ggagtttata atattaaaac tcataaacta gaggaattta gtcctaattt tgtcattacc
    20701 agtaagatac aaacggaata caaaccatgc gccagaaagc ctattttaga tggttggttt
    20761 gattttgata gatggttaga ggctttagca gttaacgata aagaagttgt agctttattg
    20821 tggcaagtca taaatgaggc tatcaatccc aaccgaacac gtaagaaaat ggtgctaatg
    20881 gttggagatg gtaataatgg aaagggtact ttccaatcct tgctggaaaa tttaatagga
    20941 cggtcaaata ttagtaattt gaaacctgac cagtttggga aagagttcta tttaggcgct
    21001 ttggaaggaa aggtttgtaa tattggagat gatatttcta acaagtacct ggatgaagtt
    21061 tctgacctta tgagtgtaat tagtggagat ccagtgcagg tcaataaaaa aagcttgcaa
    21121 cccgtggaag cacgtttcag actattgtgt atcttttcgg gtaatgattt gcctagagct
    21181 agaaataaga ccatggggtg gtatagacgg ctttgtatca ttcctttccg tgcagatttt
    21241 aacggtcaga aagaacgtca tgaaatcaaa gaccgattta taaagaacaa agagctgcta
    21301 gagtgggttt tgtttaaagt tttaaatatg ccagattttg atagctttat agaacctgaa
    21361 gcggtacaaa aaatgcttag caagtacaaa aacgataacg attatatcaa agtttgggta
    21421 gagaatttct acataccaaa cgggtggcat gaaataaacc atgttccaat gtttattgca
    21481 agaaataaat taaaagagtt tgctgaggat ataggtatag ataaacctaa acttggacaa
    21541 tttagcaatg cagtaatggc cgaattggaa aaaacaacgt catataagta ctcagccaaa
    21601 aacggaacgg ttagctctaa gttttatgac gtacttgacc cacaaggttt tcaacgtaaa
    21661 agatttgtta aaggtatatg gggaatacac ttagaagatg aagatttagg ttaggaaatt
    21721 taatactaaa aaaccaatta caccaagggt tatagcaatt taggttatgc aaaaaataga
    21781 aacataacct aaacactaac ctttgtaaac gttgatataa aagtctttgc gagtatttag
    21841 gttagtaggt tagtttttat ttctaatatc tctatataaa aaataatata tatacgtgtt
    21901 atataggcgc gaacttaaaa agtaaaacta accctaatct aacacccttg aaacgttgat
    21961 atagtaggct tttgaagggt tattttttaa aactaatcaa aacctaatct aagagaataa
    22021 aggagcaaaa cagatggcga tgaacatttt gtcaaagagt ggctaaccgt tgagcggatc
    22081 agtgaggcgc tggatggctt tattgagaat gcgaaccata acgctatagt aagcaataaa
    22141 aaacatcgaa cggattcagg aaggttttga aatagtcttt aaagagcttg atgaactaaa
    22201 agcagtacct gacaaacact aaaacattta aacaaaatgg ggtagatagt accgaccccc
    22261 ttgcaatggt gtaactacta gtgacaccct aaaaacagaa agaggaaaaa caacatgaca
    22321 ttaaaaacat tttcagataa agcaaaaaca tttaatttca cttacgaatt taaagaccaa
    22381 gacaccgccc aagtggcagg gagtgcattg atgggctaca tgattggaac ttatgtagta
    22441 ccgtctattt caatcactta caagaataaa gggacgctag tagctgagta cgtggaggat
    22501 cacaagctaa acaagacctt caaacgtatc tgtgacggtt tcaaagacta ttacaagcaa
    22561 ccagagggag atgaagcatt tgaagaacgt tataaacggg agcgcgtgct tcaactcaaa
    22621 gagtcagagg actttgagag cttgctgaat aaggtcacag actacgagct gaaactatta
    22681 gactatgctg aacgcttgct ttctgataag cctatcctta tgaactctat gactgctttt
    22741 ggtacgttgg aagtgctggg taatgaaagt attaacctat tccaaaaatt ggacgtagag
    22801 ggcgaatata aaggccttgc tgattattct ggtcaataaa cacaggggag caatcccctt
    22861 tttttacata aatcagacag aattacacac gaggtagggg gatggttaga agtttaaaag
    22921 caagactaga aaagttagaa gagtatgctg gaaagacgga atatgcaaca actgatgaat
    22981 gtatatcttt atatgtggat tgtttaagat ttgcttttca gcaagatgaa ataaagatag
    23041 atatggatga ttttattaaa acaccattta aagatattaa gctagcagac tataagaaat
    23101 caaaaaaacg tatggatgaa cttagggaaa tgactgggat aagtgagttt tcagaattag
    23161 agcaataaag cgaggtgaac agtatttgac agaattaagc agaaaaaaag aaatatttat
    23221 ggccaattat ctcatgactg ggaatgtaaa aaaagctagt gaattaagtg agatcaccag
    23281 aaagacggct tacaattact tgaacgatgc aacctttaag agaatttacc gtgaaagacg
    23341 tagcgaacaa cttaaggagt ctactacgct gttacagaat gcaagcgttg aggcagtcaa
    23401 tgtattaagg gaaatcatgc ttgataagac agtgagcccg tatgcgagac aacaaagcgc
    23461 ccaaagcatt ctaaacatgg cttataaggc ggttgaaatg gttgaggtag tggagcaatt
    23521 agaaatatta gaggcgaaga tactagatga aggcgattaa aaaccgttta aataagttga
    23581 ataagttagc ggtggttgat gaagttgata ccgtgttttt gacgcagatt gatactggac
    23641 attttgaggt aagatatagg ataggtggaa aaaatcccaa agatattata gaagtctatc
    23701 cgacaaaaga agaagcagaa aaagctattt cagaaattaa aaatacaaaa ggattgcgga
    23761 tattctggga caatttggct ttattggagg ataattagag cttatcattt atcaagcaga
    23821 taagagaaat aataaccctc cttaactcct tgagaaacga caagcagata agcgaagttt
    23881 ttagccctct tatttcggtt ctactccttg cagaatgaca aggaaataag agagataaaa
    23941 acatccctta attgcttatc aaaccacaag gagatacggg ggctatctcc ctccccacgc
    24001 acttctatga gcttcacacc gtcattgtac attttttctc acggggaagc atttgaagct
    24061 agagcgaaca tagagaaaac gaaaaaagcc aagacactct ctgtctcagc aataatctca
    24121 ataatattat tatatcacaa aggaggccga gacatgacac cagagcaggt aaaagaaaaa
    24181 ctagagggcg ttaagtggat aaacaaattt aaaagtgtgt agattacaat ctaacacaag
    24241 aaaagaaaac gcccttttgg ttgttcttta attgcttcat caactatctg agatgtttga
    24301 taagaatatt tcattgaccg tctccaatta cacataggac acaatttatt cttacaaaaa
    24361 taggcttgat ataaacgcaa actcccatct tctcgacgaa taaatcgaag agtatctcca
    24421 caagtctcaa cgcgttctat caaggtttcc ctataaccta actctttaaa aatatctgcc
    24481 aatttcaaac ttaataattt tcgtcctcgc cagtttctat ccttgcctct tttattttta
    24541 tctaaaagaa ttttatcttg attttcccac ttctccatgt tataatttac ctgtaattac
    24601 aaagaaatac aaaaatacct ttgccttttt tctcttttta taattttttc tgaacaacta
    24661 aattataaaa gatccgttga aaaaagtcaa gggcattttt ttacctaaaa agtcagtagt
    24721 atcaagggtt tagaccctgt cgaaacccta aaaatagcat gagagttatt tcctactagt
    24781 atcaagataa gaaaaaacct actcttcgag taggtttttt acggagcttt cagctccttt
    24841 tatatatcta attaccgttt ttaccgtttt cctctatatg gaaatacaat gaataaaaac
    24901 aaaactaatg ctattgttaa cagtattttc atcggaatag ggagattatc tagccatatt
    24961 tgaatagaac caaaaagctt tatatctaaa actttatcaa aaaactttat aaaaaaatat
    25021 aagactatga cactccaaaa taaccaagct ttattcataa caaactcctt gttatttaaa
    25081 ggcagaatta aaatcgttta ctgatcaact tacactcctc tctaaataaa ttaaacaatc
    25141 ttattctcaa tataataata catttttata aacaaaaaaa caagtctata tttcggtttg
    25201 ccgataactt ttttatatca tacccgcttg ttttattcca tggtctactt gaccgcaagt
    25261 aacctaggtc gacgtacttt gtccgtgccg ctccgaaacg ctacagcctt tcggctcgtc
    25321 cctgactagc gtactttgat ctagcttacg gtcaagtagc tttcacggca taaatcgctc
    25381 agaaattaca atatactttc tactaaaaat accccaaaaa tactaccttg atacaatctg
    25441 aaactacatt tttcagtcga gtattttcgt ttctaaaaaa agataaatct ctttttaggc
    25501 tctccatttc gtttttaagc tcatctttgg tttcctgtaa ttctaagggt tttatcctct
    25561 aaaaaatcaa ttctggagct cctgacggct attaattcat ctattctctt taattcctct
    25621 tttgcttgat taacattttc cataatctct ttatactcgt tcatatcttt tatactattt
    25681 attccaacaa ccttacaaga aatattaagt tcctttaatt ttagtccgat tttttaaaaa
    25741 gaattactac aaattgatac taaaaaggta caaaaaaggg gggtaatcgt cgaggtaaag
    25801 gggggtaatc gtcgaggtcg cgaatttgta aacccttgat attactgact ttctaagggg
    25861 tcaaaatttt caatactatt aaaactatta agactattaa agagcacccc ccactctttt
    25921 aagaagtggg ggtatgctat aataaaacca gtaaaaagaa aaggcgggag cggacatcac
    25981 tttttcttta gaggcactca agagaggtaa gcatggtaac agacattgaa caagcaagaa
    26041 agaactatat ggcagactat acgccagtag accttacaga cgcacacaaa ctactagaac
    26101 tagctgaaaa gctacaaaac gaggatataa gtatcaacac ttacgagtta tacaaacatc
    26161 cagaagcaag agagaaatta ttttggcagg ttgctgaaga aatagatagg tcaaagacta
    26221 cagtatacct tataaggcaa aaagccatag aacacttagc aaatgtgggg taataggtga
    26281 gcacaaaaaa acgcctagaa caatctaagc gctaaagagt agtggacggt gtgcctgtcc
    26341 cgtcatctca tactatgaag ttgcgtagcg acactatcat ctctacctca cttctcttta
    26401 aactaattat accacaaagg agcgaactaa tggagctgga taagtttaaa acgatgatga
    26461 acgtcagaga gcggatgaca tgattgaaga ttttttgatt gatttggaga atatccaatt
    26521 agaggacatg gagatagatt ttaacatgga gatagacatc gatttaaaca tagattttga
    26581 aatagatgtt gaccttgatg gtttagattt gaccttacta caagaattag aagcgtaaat
    26641 gttggtaaat gtaggctgag gcttcatatt cgcctcccta tttcgcttgg tttcgtaccg
    26701 gacgattaaa acaccatgga taaactagaa gcccttagaa acgaatcagg gggacttttg
    26761 tgaggtcata atcttataaa ccacgcgctt catggtataa tatacctatc agcaaccagc
    26821 aataaaaaaa gcacgtttga acgtgctagt ttcttgcctg ctgaactcat cgatttagta
    26881 gcccttttgt gggctttttt tgtggacttt ttgagaattt ttaagaactt ttaatgattt
    26941 ctaatcaaat gagatttttc aaaaagtcag taatatcaag ggtttaggcg ctataaacaa
    27001 atttaaaagt gtgtagatta caatctaaca caaaaaggga taaagtgcta accctctaac
    27061 taagggttct cagtcaataa ttttattcat ttttcgctca aaatcatatc gccccatcat
    27121 gacaacatgc tcacaattac tgcattttat tttgatatct gctcctacac gtgtaatttc
    27181 ccaacgatta gcctttttac cagtcgactt gattgtacaa gcgtgtgatt ttttcatctc
    27241 aacaaaattt ccaacttgat acatactact ctccttttct ttttcgatta tatcataaaa
    27301 gaggcgagcc aggctcaacc tctttcactt aatttgtacg aactggtgta atgagctgca
    27361 tgaagtcttc gtcagtatct gctggcacaa gagtaaatgg acgaacagct gagataaagc
    27421 taatggtcac cttttcgcta tttaaagctt taagagaatc aatcaagtaa gttgggttga
    27481 aactaatggt caaatcttca ccagtaacct gatcagtatc gatttcttcg tttactttac
    27541 caacttctgg agagtgaaca tgggcgctaa caaccccatc cttaatttca agtttcacag
    27601 taccattttg agtcgcactt gataaaagac gggcacgctc cattgactgg cgtaagttta
    27661 ccacattaaa agtaatagta gtgttaaagt ctgttggaat caagcgatct gtatcaggat
    27721 agtttccttc taggagacga gtatagaagc taatattttc gcttctaaag aggatttggt
    27781 tattggcaaa gaaaatctct acagtttcga tatcatctgt aaataccgct gaaaattcgc
    27841 gtagagaacg gctaggaatt acgacatcaa aatcatcact atttttttca agagtcaatt
    27901 ttttctggct taggcgatga gagtctgttg caactgtttt taactctttg tgttgactca
    27961 atacgaagtg gacacctgtt aaaatcggac gactctcttg tgtacttgca gcaaaggctg
    28021 tttcattaat aattttcttg agtaattttg tttcaagtat taaaggagtg cttgctgaaa
    28081 tttcttggat tcgtggatat tgttcgctat cttttccttt tagggtaatt tctgatttgc
    28141 cactggttaa aacaatttga ttttgttcaa tttctttaaa atcaagagtt acatcaggta
    28201 aactagatac tacattgata aagaaagaag cttcaagaag gatcgaacct aaagaagtaa
    28261 ttaacaaacc agcatcttca tttttttgag aaataaaatt ttcaattgaa atttgaccat
    28321 ttgaaccaat taaagtaata ccttcattgg tcacgtcaat ttttactgtt gataaaatag
    28381 gaatggcatt tttagaacta atagctctct tagtagtatt taatgcttgt agaaataaat
    28441 ttttattaat tgaaaaatga atcatggatt ctcctttatt tatttttagt attagaaaga
    28501 taatagtaat aatagagtct gtgaaatctg tggaaaacag cctttaaaca agtcatatca
    28561 agttttttag cttgtttaaa aaatgtggat aaaaaagata aaaaactaaa agttatccac
    28621 aaattatttg attttctttt tgattgattc aatttctaaa cgtaaattat cgtcttgatc
    28681 aatcaaagat tttattttgg catgggcatg aatgactgtg gtatgatctt ttcccccaaa
    28741 ttccttccca atttttggaa gactattatc tgttagttct ctagataaat acatggctac
    28801 ttgacgggcc aaaacaatat tttgaaggcg tctacttccc ttcatttctt tgatactaac
    28861 accataaaag ttaccaactt cagtttggat tttatcaatt gggatgacga gcatttggct
    28921 aacatcttgt ttgcgggctc taatggcttc tgcagcaata tcaatagtga tatccttgat
    28981 tttttttact ctggcaatta aagtgatgtc gttgatggct ccctcaagat ctcgaacatt
    29041 tgaatcaaat tgcccagcta ggtattctag agtatcactt tggaaattgt agcctaaatg
    29101 ttccgtctta ctttgtaaaa tggcaatacg tgtttcaaag tcagggggtg tgatagtttg
    29161 tgtcaatccc caactaaaac gcgtgacaag cctctcctcg agcccttcta gatgttttgg
    29221 actacgatca ctcgttagga caatctgttt ttgcttgtca tgaagggcgt taaaggtatt
    29281 gaaaaattct tcctgagttg cgactttttt tccgctgagt gactgtatat catcgattaa
    29341 caaaagatca agactacgat aggtcttttt aaacttttcc atttccccaa gtcttaggtg
    29401 atcaagaaag tcattaataa agctttcggc agggatatat ttaacacgcg cattaggaat
    29461 attttttaga atttcatttc caatagcgtt taataagtga gtcttaccaa ggcctggtcc
    29521 tccatagata aaaagagggt tataggtcag agccaaatct tcagagacag ctaaagcggc
    29581 tgatacagcc caaacatttc catccccttg aataaaatta tcaaaggtat acttttcttt
    29641 taatcccgta tctgaataag gaatagatac taactttgga ctatagtcat aaagagttaa
    29701 atttgtagct tcttcaactt gtgagctagt cgtatcttga ggtttggtga aaatatagtg
    29761 gggagttatt tcagcgtcat aaatttcaaa accagctact acaataatat cttttagttg
    29821 tttttcccag accatttcca tttcagagcg aggtagaaat atagtggcaa cattttcctc
    29881 taccttgatg agttcagctt gaatagcata gaaatcatac atggatcgag tcagtctttc
    29941 ttgtgcaaat tctaatatac gattccaaaa ttgtttttct ttcaatcctt tctcctcctt
    30001 tactatttaa aagtttaata ctagagatat tttaccatag atagcaagaa ttttccacaa
    30061 gctgtgaaaa ataatccaca atgttaccaa actttatcca caggttgggg ataaaagaag
    30121 aaattattga tttattaagc tttttatcga aaaacatagt ggataacctt gtgagataaa
    30181 aaaataaaag aacagcctta tttcaggctg ttgataattc tactatattc ttcttgattt
    30241 gaaaaagaaa taatgatttt tccactgtct tttttagata gtttaatttc tacatctaaa
    30301 ccgagtagtt ttcttaactg tttttcttca ttttgtatga aatgattagt tttttgctgt
    30361 ttcttttgtt ttttctctgt cagaagagtt tctaacttcc ttacagaaat atcttcttct
    30421 ataatccgtt gaaagaaata gtcttgttgt tccttattta acccaactag ggaacgcgca
    30481 tgggcttgtg atagtttgcc attttctact tctgagagaa tctgttctgg caaggaaagt
    30541 aaacgaatgg agttgctgat atatggacga gacttgccca tcttatctgc aatttcagca
    30601 tgggtgaatc ctttctctac gagagattca taggcgcgtg cttcttctat tgggtttaaa
    30661 ttttctctct gtaaattttc aataatggac tggaccatca tctcttggtc tgaaatctgt
    30721 ttaacaacag ctgggataga ccgtagacca gctaaaagtg aagcccgata gcgtctctct
    30781 cctgcaagga tttcataacc aataacagga gattgacgaa caataatcgg ttgaatgacc
    30841 ccattttctt tgatagactg tgctagttca tctagttttt ctctatcaaa ttcttttcgg
    30901 ggttgatagg gatttttttg tatatctgtg atagaaatca tttcaaattt ttccatgatt
    30961 ctacactaac acatcttttc tcttatgtaa agctttcttt acatagatgt caatcaagat
    31021 tctaaatcac ctgaactctt gttaagtttg atagaggtag tttcttcttt cccgttacga
    31081 tagtaggtta tcttaatggt gtctccgata gaatggttgt aaagagcact ttgtaagtct
    31141 gttgatgaag caatctcttt gtcatctact tttgtaatta catcgtattt ttcaaggtga
    31201 ccattggcag gcatattact ttgtaccgaa cgaacaacta caccagatgt aacattactt
    31261 ggaatattga gtcttctgat gtcgcttgta ctcacattag ataaattaac catctggatt
    31321 cccaaagctg gacgcgtcac ttttccgttt ttttctaact gttcaataat attgatagca
    31381 tcatttgcag gaattgcgaa accaagacct tctacagatg ttcctccatt tgtagcaatt
    31441 ttacttgagg taattccgat aacctgccct tgaatattga tcagtgggcc gccagagtta
    31501 cctgggttaa tagcagtatc agtttggatg gcttttgtag aaatagcttg tccatcttcc
    31561 gatcttaagg atacatttct attgagactg gatacgatac cttgagtgac agtatttgca
    31621 tattcagaac ctaacgggct accgatggca atagcagttt ctcctacagt taacttacta
    31681 gaatcaccaa actcagctac tgttgtcact ttttctgaag agattttgac gacagcaata
    31741 tcagagaaag tgtcagctcc gacaatttct ccaggtactt tagtcccatc tgacaatcta
    31801 atatctactt tgctggcgcc atttataacg tgattgttgg tgacgatgta agcttcttta
    31861 tcattctttt tataaataac tccagatcct tcactagaga ttcgctgaga atctgtgtca
    31921 gtatcatcat tgccaaatac gctattttgt ctgtttgccg aataagtaat aacagaaaca
    31981 acagcatctt ttactttgtt aacagcctgt gttgttgaat tttcgttctt ataggcagtt
    32041 tgtgtaatag tactattgtt gttagagttg tttacactac ttttttgagt tagttgagtt
    32101 attgaaaaac tacccaaggc tccactaaaa aagctaatga cgataacgac taataattga
    32161 aaccattttt tgtaaaatgt ttttagatgt ttcatatttg cctccatatg tttgaattac
    32221 tgaaagtata aactgactag cttaattata acttaaacac aaaagtttta cacaaactgt
    32281 ggataactct tttgaaactg tgattttctt aattgaaatc tattttttat tttgtgaata
    32341 agatgtgaaa aaatagagaa tatgttagaa tagagtcatg aaaattaaag ttgtaacagt
    32401 tgggaaactg aaagaaaagt atttaaaaga tggtatcgca gagtattcaa aacgaatttc
    32461 tagatttgct aagtttgaaa tgattgagtt atcagatgaa aaaacaccag ataaggccag
    32521 tgaatcagaa aatcaaaaga ttttagaaat agaaggtcag agaattttat caaaaattgc
    32581 tgaccgtgat ttcgttattg tgttagccat tgaagggaaa actttcttct cagaagaatt
    32641 tagtaagcag ttagaagaaa cttctataaa aggattttct actcttactt ttattattgg
    32701 gggaagttta ggattgtcat catctgtaaa aaatagagcc aatctttctg tcagttttgg
    32761 tcgcctaacc ttaccccatc agttaatgag actagttctt gttgaacaaa tctatcgcgc
    32821 ttttacgatt cagcagggat tcccctacca taaatagaaa attgactttt aattgaattt
    32881 ttggtagaat aattgtatta ggtctcatag ctcagctgga tagagcattc gccttctaag
    32941 cgaacggtcg caggttcgaa tcctgctggg atcaatataa tagcaaagct gggaattttc
    33001 ccggcttttt tcttaaaaaa gtacactttg ggagaaaaaa atgacagttg agagaatttt
    33061 atctaaaacg aaattccatt ttgtataatg ttttttgtaa gttagcttac aagaaaaaac
    33121 attttaggag attttattat gaaaaacaca gttaaattgg aacagtttgt agctttgaag
    33181 gaaaaagact tacaaaagat taaaggtggg gagatgaggt tgtcaaaatt cttccgtgat
    33241 tttattttac aaagaaaaaa gtaatgaaat aaggggaaag agtaatggat ttatttggat
    33301 ttgggacggt tattgttcat tttttaatta ttagtcacag ttaccatttt atttgtaaag
    33361 gtcaaataaa tagaaaagaa ttattcgttt ttggtgctta tacattacta acagaaatag
    33421 tatttgattt tcccttatat attctatatt tagatgggtt agggattgaa agatttttat
    33481 ttcctttggg attatattcc tattttcgat ggatgaaaca gtatgagagg gatagaggac
    33541 tattcctaag tttactacta tctcttttat atgagagcac tcataacttt ctgtccgtaa
    33601 ctttctcctc tataacagga gataattttg ttttacaata tcatttccca ttctttttcg
    33661 ttgtgacggt gttaacctat tttgttacat taaaaatcat ttactatttc catttggaac
    33721 tagcctattt tgacgaggac tacctttatc ctttcttgaa aaaagtattt tttgctttac
    33781 tattgctaca tattgtatct ttcgtttcag atatggtaag tacgattaaa catttgaata
    33841 gttttggaag tattttgtca tctattgtct ttatctctct ccttttgacc ttctttgcaa
    33901 tgaattctca taaagttcaa atggagaaag agattgcttt gaagcagaag aaatttgaac
    33961 agaaacattt acagaattac acagatgaaa ttgttggtct gtataatgaa atccgtggtt
    34021 ttcgacatga ttatgctgga atgcttgtca gcatgcagat ggcaattgac agtggtaatt
    34081 tacaggaaat tgacagaatt tacaatgaag ttttagtcaa agcaaatcat aaattgcgtt
    34141 cagataagta cacttacttt gatttgaaca acatagaaga ctcagcttta cgaagtttgg
    34201 ttgctcagtc aattgtctat gctcgaaata atggtgtaga gtttacactg gaagtaaaag
    34261 atacgattac caagcttcca attgaactat tggatttggt tcgtatcatg agcgttttat
    34321 tgaataatgc tgtcgaagga tcggctgata gctataaaaa gcagatggaa gtagcagtta
    34381 ttaagatgga aactgaaaca gttattgtga ttcagaattc atgtaaaatg acgatgactc
    34441 cttcaggaga tctatttgcc ttaggattct ccactaaggg aagaaatcgc ggagtcggat
    34501 taaataatgt gaaagaacta ctagataagt acaacaatat tattttagaa acagagatgg
    34561 aaggcagtac atttagacaa atcattagat ttaagaggga atttgaatga aagttttaat
    34621 tttagaagat gttattgaac atcaagtgag actagagaga atattggatg aaatttcgaa
    34681 agaatcgaat attccaatat catacaagac aacgggaaaa gtccgtgaat ttgaagaata
    34741 cattgaaaat gatgaagtaa atcagcttta tttcctagat atcgatattc atggaattga
    34801 gaaaaaggga tttgaagtgg ctcagctcat tcgtcattac aatccttacg ctattatcgt
    34861 ctttatcact agtcgatcag agtttgcgac tctaacctat aaatatcagg tatcagccct
    34921 agattttgtt gataaggata tcaatgatga gatgtttaag aagagaattg agcaaaatat
    34981 cttctacacg aagagtatgt tacttgaaaa tgaagatgtt gtagattatt tcgactacaa
    35041 ttacaaggga aatgatttaa aaattcctta ccatgatatt ttgtatattg aaacaacagg
    35101 ggtatctcat aaattgcgca ttattggtaa gaattttgca aaagagtttt atggtaccat
    35161 gacagatatt caggaaaagg acaaacatac tcagcgattt tattctcctc acaagtcatt
    35221 tttggtaaat ataggcaata tcagagaaat tgatcgaaaa aacttagaaa ttgttttcta
    35281 tgaagaccat cgttgtccta tttcaagatt aaaaattaga aaattaaaag atattttaga
    35341 gaaaaaatct caaaagtgat tgacaattag caagaaattg atataatggt tatatctgct
    35401 acagatagaa ggtccgttgg tcaaggggtt aagacaccgc cttttcacgg cggtaacacg
    35461 ggttcgaatc ccgtacggac tattttatcc gccatagctc agttggtagt agcgcatgac
    35521 tgttaatcat gatgtcgtag gttcgagtcc tactggcgga gtatagataa aagggaacac
    35581 agctgtgttc ctctttttgt atcaatttgt atcaccaagc attttcataa ggaagtctgt
    35641 tatttcttga gaactttctt tttttccatg tgcaatccaa gtttggcaga caccaaaaag
    35701 tgcatgagtt agatagatgc tactatattc taattcggtg gtatttagat tcagttgcat
    35761 aaatcgcttt tgtaaatctg tactaagcat gatatgaagt ttatttcgta agaaattttg
    35821 gatttcttta gtcccatttt cagaaagaag ggcagccaga agtggttctg actctagata
    35881 ttcaaaaact tctaaaatag cgtctctttt gtgatgagca tgtttttgaa aaatatattc
    35941 aaatgtatgg aatagcttgc tttgatagtg ctcaatcata tcatacttat ccttatagtg
    36001 agtatagaag ctggaacgac taattccggc tttttctact aatttgacag tagaaatttt
    36061 atcaaatggc tgttccatca gtaattgtac catagcattt tcaatagttc gctttgtttt
    36121 taagcgtttg ttactttctt gcatatttcc tccttgtaaa caaattagac tatatgtcta
    36181 aaaatagatt ttttatcttg taatttagat tttttaatgt ataatctatt atatcaaaat
    36241 tttagacaat atgtttaaaa aaggagaaac taagtttaaa gaatggaaag caattttaaa
    36301 aaaaaccaac ctttattatt gtcatgatcg ggatttctct tattccagat ctgtacaata
    36361 tcatattttt gtcatcaatg tgggatccat atgggcaatt gtctgactta cctgtggcag
    36421 ttgtaaataa tgataaagag gcttcctata atggtaatac tatggcaata ggaaaagaca
    36481 tggtgtccaa tttaaaagaa aataaaacct tggattttca ttttgtagat gaagaggaag
    36541 gaaagaaggg attggaagat ggcgattact atatggtagt gactttacca agtgatttat
    36601 ctgaaaaaac aactacatta tccaatattc aatcgacagc agcttatcaa tcattgacaa
    36661 gtgagcaaca aactgagata agtgattctg tatctcaaaa tttaactgct agtattcaat
    36721 cggctcagtc aattgtagct ttagtacaag atttacaggg aagtttagaa aacttacaaa
    36781 atcaatcttc taatctttcg actttaaaaa atcaatctaa tcaagtatca cctattactt
    36841 ctacttcttt gataggattg tcaagtggat taacagagat acaaggagat gttactagca
    36901 aattagttcc tgccagtcag tcgattgcat caggtgtaaa cgcatatact acaggtgttg
    36961 ataaagtttc tcaggacgtc atccagagag ccgttgggct tggttgaaat ctcgagctga
    37021 aataaatggt attatagctg ttttggcagg aattttggta tatggaggag ttcatcttat
    37081 tggtttaact gctaatcatg agatgagaat atttattctc atcatcctaa caagtttagt
    37141 attcatgtct atggtgacca ctttaacaac gtggaatagc cgtataggag ctttcttctc
    37201 acttattttg cttttactac agttagcatc aagtgcaggt acttatccac ttgctttgac
    37261 aaatgatttc tttagatcta ttaatccctg gttaccaatg agctattcag tttcgggatt
    37321 acgacaaaca atctccatca acaagtcatt ttcctagctg tcatactagc tctatttact
    37381 ggtttaggta tgctagccta tcaacataag aaaatggaag aagattaaaa aaatcgaccg
    37441 attaactggt cgatttttta tgccttagat gactttcgtc tgtgattata gattccaaat
    37501 agtaagagag aagtaaagga acagattgct ccagtaataa aaccattggg aatgaaggaa
    37561 agtgtaatag ttcctttccc cttgggaatg tcaactttca taaatccagt ttgagcttgt
    37621 ttaatttcta ttttcttacc atcttggtag gcagaccaac ctttgtcata aggaatggtg
    37681 aagaaaatag atgtatcttg ttggacatca tatgtagcaa aaaccttgtt tttagaagtt
    37741 gatactgtga caggttgttc tttaattttt tgaattgcct cggtgaaagt tttggtatct
    37801 aaacgataga aggtaggaga ttcaaatgat acttgtgaat ttccagggaa actaacattg
    37861 atattgaaag tttttttctc tttagtatat cctagattaa agaaggagaa gacattatca
    37921 gttgtaaaag tctttttttc accatttaca aggatgtcaa ccttcttttg tttatcgtta
    37981 gaaaagtgaa ggtttatgaa agagagataa acttggctgt tttctggaac ttcaatttga
    38041 tactggattg ctgcatcttc atttgaagaa cttgtgacac taatcaaatc attagtattt
    38101 tctatttttt ctgttttttc ataagatatt ggagaaaaat aatcaaaatt gacgttagca
    38161 agttgattta aaaatgaggc ctgattatcc aaggtatgtt cattgaactt gacatcattg
    38221 taaacagatt gactagcaac tgcaatcgga agagagtatt gattttcata tagggtaaga
    38281 ttatcttttt gatagatatc tttaaaacca tacttatcaa taggactgtc tgagatattg
    38341 tactggatac caaataaact atcagccaaa atactattat ttgcatatcg gagattgaga
    38401 ttagtcccag aggatttaaa accaagttta tctaaagtag agcttgatga acgatttcga
    38461 acagatgaaa attgagagat tccattgtag ttgaatttca tactgtcatt tcctgtctga
    38521 gtttgtagtt tttcagtacg agtaaattga tttccaatat atgttgagaa agattccata
    38581 gctgggatat ctcgactata agcacttcga gaagcaaatc cccattcctt agcaattccg
    38641 tccatttgag atgaagcatt taaactcatt tcaaccagta taaataaaga gattagaatg
    38701 gcaaatagat tcacagatat aaactttttg ataactgcaa ggagtaaaag agaatagaca
    38761 accaaaaatt caagagtaag cagaatattc aaatctgtta aaaaagaata atgcgatttt
    38821 agatagatgg tagctaaaaa tcctgctact acaagaaaaa gcgaaactaa aaaattccag
    38881 actttaagtt ctttcagacg ctttaagact tctgctgctg tgtaaattaa caaggtagag
    38941 aaaatccaag catagcgatg taaaaacatg tttggagtat gcatgccttg ccaaaataag
    39001 tcaagagctt ctatgtaaaa gcttgcaatt agaaatgcaa agaatattac atatatgagt
    39061 ttcacgtgaa acttaataga tttcagcgta aaaaataaaa tggtcaaaat aaagggaagt
    39121 agtccaacaa aaatcattgg gatggcccca tactttgttg tgtcaaagga accaatgaat
    39181 tgcttagcaa agagatcaag ataccagcta ctttcagttt gaaactttgt aacttcagtc
    39241 aatttttccc catgtgtctg taaatcaaat agagtgggaa gagtcataat caaactagcc
    39301 ataccagcta aaaaggagat aactatgaaa tcaagaacag atgattttcg agtcttaaag
    39361 tcccacgaaa tttgacagag ataccagaaa ataagaaaca atactgtcat atatccaaaa
    39421 taataatttt gaataaataa gattgacaga cttgtaaagt acaataggag tttcttttca
    39481 gttatcagta gatgtaaacc agttataatt aaaggaatca agataaaaac atctagccag
    39541 gtttttatct ctaattgact gacagtgaaa ctcatcagag cataggaagt agataaggct
    39601 agttttaaag tctgagggat agattgaaac aatttattca aactaaaaaa ggttgacaga
    39661 ccaatcaatc caaattttaa gagagtggtc agatagacag catctggcat attcgttaga
    39721 tcaaaaaagt aaactagagg cgcgagaaaa ctacccaagt aataactaga tagggcatag
    39781 aagtttagcc ctagaccact tgtaaaggtg taaaacagac tactatttcc atgtaggata
    39841 tttcgtaagg ctacatcaaa aataacgtat tgatgaaagc catctcctaa tagaggagag
    39901 ttgtcgctat tccagtagat accttgagat agatatactc cagacataat cactacagga
    39961 atgatgaaag aaataaaata ggttcgatat gtttttaaaa atgatttcat gttacctcgt
    40021 agaatgatag aaaactcagt tggttaaccc aactgagttt tgaagtttta tttagtcttt
    40081 ccaaagttct ttaacttttg cttgtacttc tgcattttct aggaattcat cgtaggtttc
    40141 atcgatacgg tcaatgacgc catttttaga taagacaatg atatggttag ccaaagtttg
    40201 aataaactcg tggtcatggc tggcaaagat gattgattct ttaaagtttt tcaatccatc
    40261 attcaagctt gagatagatt ccaagtccaa gtgatttgtt ggatcatcaa gtacaaggac
    40321 atttgatttt aagagcatga gttttgaaag catgacacga actttttctc cccctgacaa
    40381 gacatttaca ggtttgttaa cttcatctcc agagaagagc atacggccga ggaaaccacg
    40441 taggaaagta ttgtcatcat cttctttact tgcgaattga cgcaaccagt caagaattga
    40501 ttctcctcct gcaaaatcag ctgagttatc ttttggtagg taagattgac tagttgtaac
    40561 tccccacttg acagttcctt catagtcaat atctcccatg attgcacgaa ttaatgcagt
    40621 cgtttgaata tcattttgtc caataagtgc tgtcttatca tctggacgca agatgaaact
    40681 aatattatcc aagatagttt caccatcaat ctttacagtt agattttcta ctgtcaagag
    40741 atcattacca atctcacgtt ccgctttaaa gttgataaat ggatatttac gactagatgg
    40801 tacaatctct tctagctcaa tcttatcaag cattttctta cgtgatgttg cctgccttga
    40861 cttagaagca ttggcagaga aacgagcaac gaattcttgc aattgtttaa ttttttcttc
    40921 tgctttagca ttacggtctg ctagcaattt agcagcaagc tcagaagatt ccttccagaa
    40981 gtcgtagttt ccgacataga gtttgatttt tccaaagtca aggtcggcca tgtgagtaca
    41041 aactttgttt aagaagtgac ggtcgtggga tactacgata actgtgttat caaagtcaat
    41101 caagaagtct tctaaccaag taatcgattg gatatccaaa ccgttagtag gctcgtccaa
    41161 gagaagaaca tctggtttac caaaaagtgc tttggcgagg agaaccttta ctttttcacc
    41221 gttggccaat tcgctcatgt tttggtagtg taattcttct ggaatgttta ggttttgaag
    41281 tagttgagag gcttcactct ctgcttccca acctccaagt tcggcaaact ctccttcgag
    41341 ttcggcagca cgaaccccgt cctcgtctga gaaatcttcc ttcatgtaga tagcatcttt
    41401 ctctttcatg atgctataaa gtttttcatt tcccatgata acgacatcaa tggcacgttc
    41461 atcttcgtag tcaaagtgat tttgacgaag aacagagaga cgttcatctg gaccaagaga
    41521 gatgtgacca gtagtaggtt cgatatctcc agctaaaatt tttaaaaagg ttgattttcc
    41581 ggcaccatta gcaccgatta atccgtaagt atttccttct gtaaatttga tattgacatc
    41641 atcaaaaagt ttgcgatcac taaaacgtag tgaaacatca gatactgtaa gcaatgtttt
    41701 tctcctatat gtgtaatata tttattctac tagaaaatac agaaatattc aaatttttat
    41761 ttgtcaattt tgtgtaaatt atatttacag tatcctttac acaaatctgt aaaaagcaag
    41821 gctgatttat tttgataaat tacggttatt tcattaaaaa aatgctataa ttgaaaggac
    41881 tatatcgaag gagaacaaaa tgactaaacc cattatttta acaggagacc gtccaacagg
    41941 aaaattgcat attggacatt atgttggaag tctcaaaaat cgagtattat tacaggaaga
    42001 ggataagtat gatatgtttg tgttcttggc tgaccaacaa gccttgacag atcatgccaa
    42061 agatcctcaa accattgtag agtctatcgg aaatgtggct ttggattatc ttgcagttgg
    42121 attggatcca aataagtcaa ctatttttat tcaaagccag attccagagt tggctgagtt
    42181 gtctatgtat tatatgaatc tagtttcgtt agcacgtttg gagcgaaatc caacagtcaa
    42241 gacagagatt tctcagaaag gatttggaga aagcattccg acaggattct tggtctatcc
    42301 aatcgctcaa gcagctgata tcacagcttt caaggctaat tatgttcctg ttgggacaga
    42361 tcagaaacca atgattgagc aaactcgtga aattgttcgt tcttttaaca atgcatataa
    42421 ctgtgatgtc ttggtagagc cggaaggtat ttatccagaa aatgagagag cagggcgttt
    42481 gcctggttta gatggaaatg ctaaaatgtc taaatcacta aataatggta tttatttagc
    42541 tgatgatgcg gatactttgc gtaaaaaagt aatgagtatg tatacagatc cagatcatat
    42601 ccgcgttgag gatccaggta agattgaggg aaatatggtt ttccattatc tagatgtttt
    42661 tggtcgtcca gaagatgctc aagaaattgc tgatatgaaa gaacgttatc aacgaggtgg
    42721 tcttggtgat gtgaagacca agcgttatct acttgaaata ttagaacgtg aactgggtcc
    42781 tattcgtgag cgccgtattg aatttgctaa ggatatggga gaagtttata atatgattca
    42841 aaaaggtagt gaaagagcgc gtgaagttgc gggtcaaacc ctatctgagg taaaaggggc
    42901 aatgggactt cattacttta actaagttta ttttacaaga aactatcatt tctatctcga
    42961 agaaaagata gttttttatt tacccctgta acatttgaca aatttttata gaatggtatg
    43021 atagatacaa tataaaaaga gtcaagctca aaaagaaaga aaagaggaaa cttcgaatgt
    43081 ctaattggga cactaaattt ttgaaaaaag gttttacctt tgatgatgta ttgcttattc
    43141 cagctgaaag tcatgtgttg cctaacgatg cagatttaac aactaaattg gcagataatt
    43201 tgactttaaa tatcccaatt attaccgctg ccatggacac agttacagag agtcaaatgg
    43261 ccattgctat tgctcgtgca ggtggtctcg gagttatcca taaaaacatg tcaattgctc
    43321 aacaagcaga cgaggttcgt aaggtaaaac gttctgaaaa tggagttatt attgatccgt
    43381 tcttcttgac gcctgaacat acaattgctg aagcagatga gcttatgggt cgttaccgca
    43441 tcagtggtgt tccagttgtt gaaacacttg aaaatcgtaa attggttggt attttgacaa
    43501 accgagatct tcgttttatt tcagattata atcaaccaat ttcaaaccat atgactagtg
    43561 aaaatcttgt tactgctcct gtgggtacgg atcttgcaac ggctgagagt attcttcaag
    43621 agcatcgtat tgaaaaactt ccgttggtcg atgaagaagg cagtctttct ggtttgatca
    43681 ctatcaaaga tattgaaaaa gttattgagt ttccaaatgc ggctaaagat gagtttggtc
    43741 gtcttctagt tgcaggtgca gtaggtgtta cttcagatac atttgaacgt gcagaggctc
    43801 tttttgaggc aggagcggat gcgattgtta ttgatactgc acatggtcat tctgcaggtg
    43861 tcttgcgtaa aattgccgag attcgtgctc atttcccaga tcggactttg attgctggaa
    43921 atattgctac tgctgaaggt gcacgtgccc tttatgaagc gggtgtagac gttgttaagg
    43981 ttggtattgg accaggttct atctgtacta ctcgtgtgat tgctggtgtt ggtgttccgc
    44041 aagtaacagc tatctacgat gctgcagctg ttgcgcgcga atatggtaaa acgattattg
    44101 ctgacggtgg gatcaagtat tctggagata ttgtaaaagc acttgctgca ggtggaaatg
    44161 ctgttatgct tggatctatg tttgctggaa ctgatgaagc tccaggcgaa actgaaatct
    44221 tccaaggacg taaattcaag acttaccgtg gtatgggatc aattgctgct atgaagaaag
    44281 gttcaagcga ccgttatttc caaggttctg tcaatgaagc aaacaagctc gttccagaag
    44341 gaattgaagg tcgtgttgct tataaaggag cggcagctga tattgttttc caaatgattg
    44401 gtggtattcg ctctggtatg ggttactgtg gtgcagctaa ccttaaagaa ctacacgata
    44461 atgctcaatt tattgaaatg tctggtgctg gtttgaaaga aagccatcct catgatgtgc
    44521 aaattactaa tgaggcacca aattattcta tgtaaaaaac aatgaaaaga actccagtga
    44581 aaacaggagt tcttttacaa tgttgtcaat ttccatttac agcagcttta ccatcctgaa
    44641 tagtgaagat acttagattt tctggcagat tttgaagatg gtctaagctt gttgttgtga
    44701 taaaggtttg gattgattga gaaatcgttt ctaataattt taactgtcta gtgttgtcaa
    44761 gttcactcat cacatcgtca agcagtaata tcggagattc tgtggtaatg ctttccatta
    44821 attcgatttc tgctaatttt atcgagagga cgagactacg atgttgacct tggcttccga
    44881 aactagcatc catcccattt atataaaaag aaatgtcatc tcgatgagga ccgacaccag
    44941 tattcttttt aaataaatct ctggatctac ttttttctaa agcaattttg aaagattcgg
    45001 ataagttttg tttgtcagtt atattgacag aagattgata ggatattgac aactcttcga
    45061 tctgattaga gagttcaaaa tgtttcttac gcccaaatga ttctagtttt tttatgaaat
    45121 ctaagcggtg attcattaca cgacatccat aatcaactag ctgatcatct aacacagaaa
    45181 ggaatgtttc atctattttt tgagctgatt ttaggtaagt gtttctttgc tttaggatgt
    45241 ggttataatt ggttaagtca gataaataga ttggcttaat ttgcccaagt tccatatcaa
    45301 tgaattttcg tcgaatcgaa ggtgctcctt taattagttg taaatcttca ggagcaaata
    45361 agacaacatt catgtgtcct acataatctg aaaggcgtgc ctgttttaag tgattaactt
    45421 ttgttacacg gcctttttgt gttagttcga tttctagggg aatggatcca gtttttttct
    45481 gaacgagacc tgaaagatga agttgttcct catcaaaatg aatgagattt ttatctgttc
    45541 gagttcgatg actacgcgtt aaggctaaaa aatagatagc ctctaacatg tttgtttttc
    45601 cttgtgcatt acgtcccaaa aagacattca atttaggatt aaagtctatt ttcgtttctt
    45661 tgtaattacg aaaagtcttg agagatagat gttgtagcca catgattatc taccagggaa
    45721 tcgtggagct tgttggcttt taggtgatga agcaggtttc gatttgtctt ttttaactcc
    45781 cttattcatc tttttgacaa gtttagcgat ccgttctttt tcaactttat cagcttggta
    45841 ttcatcttgt tcttcagaag taggttgtgt caacaagatg tcaatgttca tgtcagggat
    45901 gtcaacttta tcgccaatac gaagtttttt tccacgacga ctctctaatt ccctattaaa
    45961 gtaaacagaa tgttcagaga gaaatgattt aatagctcct ccgctatgtg taattccaag
    46021 ttctttgagt agtgcttgga gggtaataaa ttcttcaaat aatttgtatt ccataattca
    46081 cctcaatctt tggtattata ccatattttc ctaaaaatag tgagagagac agcgagaaat
    46141 gtaagcgatt tttatttcaa aagtgttaca gggaacaaga aaatttcagg ttttcgtgat
    46201 ataatagaag tctgtatata aggaggtaaa tcatggagtt agtgcatgga atttcaacac
    46261 attttatcca atcaaaaaag tttaaaacaa acaaaattac cgtgcgtttt accgctccat
    46321 tatcccttga tacgattgca ggtcacatgt tgagtgcaag tatgctagag actgctaatc
    46381 agatgtaccc cacttctcaa gatttgagga gacacttggc cagtctatac ggtacagata
    46441 tgtcaaccaa ttgtttcaga agagggcaaa gccacattat agaattgaca tttacctatg
    46501 ttcgtgatga gtttttaagt aggaaaaacg tgctaacctc tcagattttg gaacttgtaa
    46561 aagaaactct tttttcaccc gtagtagttg ataatgggtt tgatccggcc ttatttgaaa
    46621 ttgagaaaaa acaattgcta gcaagtttag cagctgatat ggatgattct ttttattttg
    46681 cacataaaga attggataaa ttgttttttc atgatgaacg tcttcaattg gaatatagtg
    46741 atttacgaaa tcgtatttta gctgaaactc cacaaagttc ttattcttgt ttccaagaat
    46801 ttttagccaa tgatcgaata gatttctttt tcctaggtga ttttaatgag gttgaaattc
    46861 aaaatgtatt agaatcattt ggctttaaag gtcgaaaagg agatgtgaag gttcagtatt
    46921 gtcaacctta ttctaatatc cttcaggaag gtatggttcg gaaaaatgtg ggacaatcca
    46981 ttttggaatt aggttatcat taccgttcta aatatggtga tgaacaacat ttacccatga
    47041 ttgtaatgaa tggtttactt ggtggatttg ctcactctaa gctctttaca aatgtccgtg
    47101 aaaatgctgg attagcttat accatttcaa gtgagcttga tttatttagt ggattcttga
    47161 ggatgtatgc tggtatcaat cgagaaaatc gtaaccaggc tcgtaaaatg atgaataatc
    47221 aactgcttga tttaaaaaaa ggttatttta cagagtttga gttaaatcag accaaggaaa
    47281 tgattcgttg gtcgttgtta ctttctcaag ataatcaatc ttcattgatt gaacgtgctt
    47341 atcaaaatgc cttatttgga aaatcttcag cagactttaa aagttggatt gcaaagcttg
    47401 aacaaattga caaagatgct atttgtagag tagctaataa tgtgaaacta caagcgattt
    47461 actttatgga aggaatagaa tgacaaaggt tgtttttgaa gaaaaatact atccagctgt
    47521 aaaagaaaag gtttatcgaa ctcgtttggc caacggattg acagttgctc ttttgcctaa
    47581 aaaggaattt aaagaggttt acgggagtgt cactgtacag tttggttcgg tagatacgtt
    47641 tgtcacagaa gttgacggag atgtaaaaca atatcctgga ggaattgctc attttcttga
    47701 acataaatta tttgagagag aagattctag tgatttgatg tcggctttta cgagtatagg
    47761 tgcagatagt aatgccttta caagctttac aaaaacaaac tatctttttt cagcaacgga
    47821 ttatttttta gaaaatttag atttacttga tgaattggta acatcagcac actttactga
    47881 agcttccatt ctgacagagc aggatattat tcagcaagaa cgagaaatgt accaagatga
    47941 tccagattcg tgtttattct tttcaacttt agcgaatttg tatcctggta cacctttagc
    48001 aactgatata gttggaagtg aggagtccat ttcccaaatc aatctaacta atttgcaaga
    48061 aaattttaca aagttttaca aacctgtaaa catgtctctg tttttagttg gtaattttga
    48121 tgtggagcga gtacaggact attttgaaag caaagaactg aaagattcag attttcagga
    48181 agtagcaaga gaaaagttgt ttttacagcc tgtaaagcta acagatagta tgagaatgga
    48241 agtatcttct cccaaactag cgattggagt tagaggtaag cgagaagttt ctgaagcgga
    48301 ttgctatcga catcatattt tattaaaatt attgtttgca atgatgtttg gttggacttc
    48361 ggatcgtttt caaaaatgtt atgaatcagg taaaattgat gcgtccttat ctctggaagt
    48421 tgaaataaca agtcgctttc attttgtcat gttgacaatg gatacgaaag agccagttgc
    48481 tttgtctcat caatttagga aggctattcg taattttaca aaggatttag atattacaga
    48541 ggaacattta gatattatca aaagagagat gtttggcgaa tttttcagta gcatgaactc
    48601 tcttgaattt attgcaacgc aatatgatgc ttttgaaaat ggtgagacaa tttttgattt
    48661 gccgaaaatt ttacaggaaa ttactttaga ggatgtcctt gatgctggac atcatttaat
    48721 agatgatggt gacatagttg attttacaat atttccatcg tagtaaccta tcataataga
    48781 cactagaaag aagggatgac aagtatgaga aaaaaaacaa ttggagaggt tttacgatta
    48841 gctagaatca atcagggatt gagtttagat gaattgcaga aaaagacaga aatccagtta
    48901 gatatgttgg aagcaatgga agcagacgat ttcgatcaac ttccaagtcc tttttacacg
    48961 cgttctttct tgaaaaaata tgcatgggct gttgagttag atgaccaaat tgttttggat
    49021 gcttatgatt ctgggagtat gattacttat gaggaagtag atgttgatga agatgagttg
    49081 acaggtcgta gacgttcaag taagaaaaag aagaaaaaaa catcattttt acctttattt
    49141 tattttatcc tttttgcttt atcgatttta atttttgtga cttattatgt ttggaactat
    49201 attcaaactc aaccagagga gccttctctt tctaattaca gtgtggttca atcaacaagt
    49261 tcaactagct ctgttcccca ctcctcaagt agtagttctt ctagtataga atcagctata
    49321 agtgtatcag gcgaaggaaa tcatgtagaa atcgcttata agacaagtaa ggaaacagtt
    49381 aaattgcaat tggcagtttc agatgttaca agttgggtca gtgtttcaga aagcgaactt
    49441 gagggcggtg taaccttatc gccaaagaag aaaagtgcag aagcaacagt tgcaactaaa
    49501 agtcctgtaa caattacgtt aggtgttgta aaaggtgttg atttgacagt agataatcag
    49561 actgttgatt tatcgaaatt aacagctcag actggacaaa tcactgtaac ctttactaaa
    49621 aattaaggaa aaacgaatga aaaaagaaca aattcccaat ctcttaacaa taggtcgaat
    49681 tctctttata cctattttta tctttatttt aacgatagga aattcgatag agagtcatat
    49741 agttgcagct attatctttg ctgttgccag tattaccgac tatttagatg gatatttagc
    49801 tcgtaaatgg aatgtggtca gtaattttgg taaatttgca gatcctatgg cggataagtt
    49861 actagttatg tcggctttta ttatgttgat tgagttaggt atggctccgg cttggattgt
    49921 tgcagtgatt atatgtcgtg agttagctgt gacaggttta aggcttttat tggttgaaac
    49981 tggtggaaca attttagcag cagcaatgcc tggaaaaatt aaaactttta gtcagatgtt
    50041 tgctattatt ttcttgctat tacattggac tttgcttggt caagttctac tttatgtagc
    50101 cttatttttc actatctact ctggctatga ctattttaag ggtagtgcct atgtatttaa
    50161 agggacattt ggttcgaaat gaaatcaata attgatgtaa aaaatctttc ttttcgctat
    50221 aaagaaaatc agaactacta cgatgtgaag gatattacgt ttcacgtgaa acgtggagaa
    50281 tggctttcga ttgtagggca taatggtagt ggtaaatcaa cgacggttcg attaattgat
    50341 ggcttactgg aagcagaatc cggagagatt gtaattgatg gccaacgttt gactgaggaa
    50401 aatgtttgga atatacgtcg tcaaatcggt atggtttttc aaaatccaga caatcaattt
    50461 gttggagcga ctgttgaaga tgatgttgct tttggtttgg aaaatcaggg actttctcgt
    50521 caagaaatga aaaagagagt ggaagaagct ctggctttag ttggcatgtt ggactttaaa
    50581 aagagagagc cagcgcgtct atcaggtggt caaaagcaac gtgtggccat tgcaggtgtt
    50641 gtagccctaa gaccagctat tttaatctta gatgaagcaa cgagtatgtt ggatcctgag
    50701 gggcgtagag aacttattgg gacagtaaaa ggaattcgaa aagactatga tatgacggtc
    50761 atttctatta cccatgattt ggaagaagtc gccatgagtg atcgcgtatt ggtcatgaaa
    50821 aaaggggaaa ttgaatcaac tagtagtcca agggagcttt tctctcgaaa tgatttagat
    50881 caaattggat tagacgatcc ttttgctaat caattaaaaa aatctttgag ccagaatggc
    50941 tatgatttac ctgaaaatta tttgacagaa agtgagctag aggataagct atgggaattg
    51001 ctctagaaaa tgtgaatttt acatatcaag aaggtactcc cttagcttca gcagctttgt
    51061 cggatgtttc tttgacgatt gaagatggct cttatacagc tttaattggg cacacaggta
    51121 gtggtaaatc aactatttta caactcttaa atggtttatt ggtgccaaat caagggagtg
    51181 tgagggtttt tgatacctta atcacctcga cttctaaaaa taaagatatt cgtcaaatta
    51241 gaaaacaggt tggcttggta tttcagtttg ctgaaaatca gatttttgaa gaaacggttt
    51301 tgaaggacgt tgcttttgga ccgcaaaatt ttggagtttc tgaagaagat gctgtgaaga
    51361 ctgcgcgtga gaaactggct ctggttggaa ttgatgaatc actttttgat cgtagtccgt
    51421 ttgagctgtc agggggacaa atgagacgtg ttgccattgc aggcatactt gccatggagc
    51481 cagctatatt agtcttagat gagccaacag ctggtctaga tcctctaggg agaaaagagt
    51541 tgatgaccct gttcaaaaaa ctccaccagt cagggatgac catcgtcttg gtaacgcatt
    51601 tgatggatga tgttgctgaa tatgcgaatc aagtctatgt aatggaaaag ggacgtttag
    51661 taaagggggg caaaccaagt gatgtctttc aagacgttgt ttttatggaa gaagttcagt
    51721 tgggagtacc taaaattacg gccttttgta aacgattggc tgatagaggc gtgtcattta
    51781 aacgattacc gattaagata gaggagttca aggagtcgct aaatggatag tatgatttta
    51841 gggcgttata tcccagggga ttcgattgtt caccgattgg atccacgtag caaattgctt
    51901 gctatgatgc tactgatttt gattgtgttt tgggctaata accccttgac gaatctgatt
    51961 ctttttatag cgacagggat atttattgcc ttgtcaggag tatctctttc attttttatt
    52021 cagggcttga agtctatgtt tttcttgatt gccttcacaa ctatttttca actatttttc
    52081 atttctaatg ggaatgtttt atttgagttt tcgtttgtga gaatcacgga ttatgctttg
    52141 caacaagctg ggattatttt ttgtcgcttt gtattgatta ttttcttttc aactttgtta
    52201 accttaacaa ccatgccttt aagtttggca tcagctgtcg aagctttatt agcaccttta
    52261 aagcgtgtga aagttccagt tcatgaaatt ggattgatgc tgtctatgag tttgcgtttt
    52321 gtcccaacct tgatggatga tacgacgcgg attatgaatg cacagaaagc tcgtggagtg
    52381 gattttggag aaggaagcat cgttcaaaaa gtaaaggcga tgattcccat tttgattcct
    52441 ctttttgcga caagtttaaa acgtgcagat tccttggcta tcgctatgga agcgcgtggc
    52501 tatcagggtg gaaaaggcag aagtcaatac cgacaattga aatggactct aaaggatacg
    52561 ctgaccattc ttgttattct cgtacttggt tgttgtttat ttttcttaaa atcttagtag
    52621 ctttcaggaa ttgataaaaa gttactgtaa cagtttttga tataaaggta ggaatatgaa
    52681 ccgttttaaa aaatcaaaat atgtcattat tgtttttgtc actgttctgc ttgtgtcagc
    52741 tctcttagcg acgacttatt caagtacaat tgtgacaaaa ttaggagatg gaatctcatt
    52801 ggttgataga gttgtacaaa aaccttttca gtggtttgat tctgtcaaat cagatttggc
    52861 tcatttgaca cgaacatata atgaaaatga aagtttgaag aaacagcttt accaattaga
    52921 agttaaatca aatgaggtgg aaagtttaaa gacagaaaat gaacaactgc gccaattgct
    52981 tgatatgaag tctaaattgc aagccacaaa gactttagca gcagatgtta ttatgcgttc
    53041 tccggtatct tggaagcagg agttgacctt agatgcaggt agatcaaaag gtgcttctga
    53101 gaacatgtta gctattgcaa atggtggctt gattgggagt gtttcaaaag tagaggagaa
    53161 ctctactata gtcaaccttc tgacaaatac ggaaaatgct gataagattt ctgttaaaat
    53221 tcaacatggc tctactacaa tttatggaat tattattggc tatgacaagg aaaatgacgt
    53281 tcttaaaatt agccaattaa atagtaatag cgatattagt gcgggagata aggtgactac
    53341 tggtggatta ggaaacttta acgttgctga tattcctgtt ggtgaagtgg ttgccacaac
    53401 gcatagtaca gactatttga cacgagaagt aactgttaaa ttgagtgcag atactcataa
    53461 tgtagatgtg atagaattag tggggaattc ataatgagac agttgaagcg agttggagta
    53521 tttttattgc ttcctttctt tgttctaatt gacgcccata ttagccagct tctgggctca
    53581 tttttccccc atgtacattt ggctagtcat tttctttttc tatttctctt atttgagacg
    53641 atagaagtat cagagtatct ctacctagtc tattgttttg ttataggctt ggtttatgat
    53701 gtttactttt tccatctaat agggattaca actctcttat ttatcttatt gggagccttc
    53761 cttcataaat tgaatagtgt tattttgttg aatcgttgga caagaatgct agctatgatt
    53821 gtgctgacat tcctgtttga aatgggtagt tatcttttgg cttttatggt agggttgaca
    53881 gtagatagca tgtcgatttt tatagtctat agcttggtac cgacgatgat tttaaatttt
    53941 ttatggatta ctgtttttca atttattttt gaaaaatatt atctataaga acgacatata
    54001 aatgtaacaa aggcgtaata tttattaggc ctttttttgg tatactagta ttgtctttaa
    54061 aagaaggagt atctacgtaa tatgaagaaa aaaatcttag cgtcactttt attaagtaca
    54121 gtaatggttt ctcaagtagc tgttttaaca actgcgcatg cagaaacgac tgatgacaaa
    54181 attgctgctc aagataataa aattagtaac ttaacagcac aacaacaaga agcccaaaaa
    54241 caagttgacc aaattcagga gcaagtatca gctattcaag ctgagcagtc taacttgcaa
    54301 gctgaaaatg atagattaca agcagaatct aagaaactcg agggtgagat tacagaactt
    54361 tctaaaaaca ttgtttctcg taaccaatcg ttggaaaaac aagctcgtag tgctcaaaca
    54421 aatggagccg taactagcta tatcaatacc attgtaaact caaaatcaat tacagaagct
    54481 atttcacgtg ttgctgcaat gagtgaaatc gtatctgcaa acaacaaaat gttagaacaa
    54541 caaaaggcag ataaaaaagc tatttctgaa aaacaagtag caaataatga tgctatcaat
    54601 attgtaattg ctaatcaaca aaaattggct gatgatgctc aagcattgac tacgaaacag
    54661 gcagaactaa aagctgctga attaagtctt gctgctgaga aagcgacagc tgaaggggaa
    54721 aaagcaagtc tattagagca aaaagcagca gctgaggcag aggctcgtgc agctgcggtg
    54781 gcagaagcag cttataaaga aaaacgagct agccaacaac aatcagtact tgcttcagca
    54841 aacactaact taacagctca agtgcaagca gtatctgaat ctgcagcagc acctgtccgt
    54901 gcaaaagttc gtccaacata cagtacaaac gcttcaagtt atccaattgg agaatgtaca
    54961 tggggagtaa aaacattggc accttgggct ggagactact ggggtaatgg agcacagtgg
    55021 gctacaagtg cagcagcagc aggtttccgt acaggttcaa cacctcaagt tggagcaatt
    55081 gcatgttgga atgatggtgg atatggtcac gtagcggttg ttacagctgt tgaatcaaca
    55141 acacgtatcc aagtatcaga atcaaattat gcaggtaatc gtacaattgg aaatcaccgt
    55201 ggatggttca atccaacaac aacttctgaa ggttttgtta catatattta tgcagattaa
    55261 tttacagagg gactcgaata gagccctctt ttcaggtttt accgtgacaa tccctattaa
    55321 aaattatatc aaaatagctt gaaaatattg gaaaagtatg gtaaaatgaa aattgtcgtg
    55381 tgaacgataa tactcattct tgatgaattg tgaagcagtt gcccttgggt cgttttgcga
    55441 gttgaagtca agaagaggaa aaaaacaaaa aggagaaata ctcatggcag taatttcaat
    55501 gaaacaactt cttgaggctg gtgtacactt tggtcaccaa acccgtcgct ggaatcctaa
    55561 gatggctaag tacatcttta ctgaacgtaa cggaatccac gttatcgact tgcaacaaac
    55621 tgtaaaatac gctgaccaag catacgactt catgcgtgat gcagcagcta acgatgcagt
    55681 tgtattgttc gttggtacta agaaacaagc agctgatgca gttgctgaag aagcagtacg
    55741 ttcaggtcaa tacttcatca accaccgttg gttgggtgga actcttacaa actggggaac
    55801 aatccaaaaa cgtatcgctc gtttgaaaga aattaaacgt atggaagaag atggaacttt
    55861 cgaagttctt cctaagaaag aagttgcact tcttaacaaa caacgtgcgc gtcttgaaaa
    55921 attcttgggt ggtatcgaag atatgcctcg tatcccagat gtgatgtacg tagttgaccc
    55981 acataaagag caaatcgctg ttaaagaagc taaaaaattg ggaatcccag ttgtagcgat
    56041 ggttgacacc aatactgatc cagatgatat cgatgtaatc atcccagcta acgatgacgc
    56101 tatccgtgct gttaaattga tcacagctaa attggctgac gctattatcg aaggacgtca
    56161 aggtgaggat gcagtagcag ttgaagcaga atttgcagct tcagaaactc aagcagattc
    56221 aattgaagaa atcgttgaag ttgtagaagg tgacaacgct taatttatac aaatagtaat
    56281 tacctaggag ggcggggctt agcccggctc tcctattttc aaaaaatata ggagaattaa
    56341 aatggcagaa attacagcta aacttgtaaa agagttgcgt gaaaaatctg gtgccggtgt
    56401 tatggacgct aaaaaagcgc ttgtagaaac agacggtgac atcgaaaaag cgattgaatt
    56461 gcttcgtgaa aaaggtatgg ctaaggcagc taagaaagct gaccgtgttg ctgcagaagg
    56521 tttgactggt gtttatgtta acggtaatgt tgcagcagtt attgaagtaa acgctgaaac
    56581 tgacttcgtt gcaaaaaacg ctcaattcgt tgaattggta aatactacag ctaaagtcat
    56641 tgctgaagga aaacctgcta acaatgaaga agctcttgct ttgataatgc cttcaggtga
    56701 aactcttgaa gctgcatacg tatctgcaac agcaactatc ggagagaaaa tctcattccg
    56761 tcgctttgca ttgattgaaa aaacagacgc acaacacttt ggagcatacc aacataacgg
    56821 tggacgtatc ggtgttattt cagttgttga aggtggagac gaagcacttg ctaaacaatt
    56881 gtcaatgcac atcgcagcga tgaaaccaac agttctttct tacaaagaat tggatgagca
    56941 attcgttaaa gatgagttgg cacaattgaa tcacgttatc gaccaagaca acgaaagccg
    57001 tgcaatggtt aataaaccag ctcttccaca cttgaagtat ggatcaaaag ctcaattaac
    57061 tgatgatgtt attgctcaag ctgaagctga catcaaagct gaattggctg cagaaggcaa
    57121 accagaaaaa atctgggaca aaattattcc aggtaaaatg gatcgcttca tgcttgataa
    57181 cactaaagtt gaccaagctt acacacttct tgcacaagtt tacatcatgg atgacagcaa
    57241 gacagttgaa gcataccttg aatcagttaa cgcttcggta gttgagtttg ctcgctttga
    57301 agttggtgaa ggtatcgaga aagctgcaaa cgacttcgaa gctgaagttg cagctacaat
    57361 ggcagcagcc ttgaataact aataatagaa aggaagcaaa ttgcttcctt ttttgtatgc
    57421 agtcgatcct tatagggaga gcttcctatt ttcaaggtaa aaataaaaag ccctataata
    57481 agggccaatt gtatttagga gactaaactt caaattcata gagtgctgta gagagataac
    57541 gttcaccgtt atctggtgct agagcaagga cttttttacc tgtacctaat tttttggcaa
    57601 cctcgatggc tccgtagata gctgcagctg aggaaatccc tacaaggaag ccttcttttc
    57661 caccaatttc acgtccgagt gcaagagcat catctgatgt tacacgaacg atactatcat
    57721 aggctttagt atcaagtgta tcaggaataa atccagctga gataccttga attttgtgag
    57781 gaccaggttt ttcaccagat agaatagcag attcatcagc ttccactgca taaacttgaa
    57841 tgttagaatt ttctgatttg agtgcatgag aaacaccaga aatcgttcca ccggtaccta
    57901 ctccagcaac aaaggcatct aatccatctt taccgaaagc agctagtatc tcagctcctg
    57961 ttgttctttc gtgtacttct ggattagctg gattgtcaaa ttgaagagga aggaaaccat
    58021 cacgttcagc agcgatttct tgagccttag caatagcacc tttcattccc tcgctaccag
    58081 gagttaggac gagttcagca ccataagctt ggataatttt acgtcgttct acactcatag
    58141 tttcaggcat aacgatgacg actttatacc ctttagcagc acctacccat gaaagtccaa
    58201 taccagtgtt tccacttgtt gcttcaacaa tagtagaacc aggtttcaga ataccatctt
    58261 gttcagcttt ttcaatcatg ctaagggcaa tacggtcttt tacagatgaa ccaggattaa
    58321 atgcttcaag ctttatatag acgtctgcag caccttctgg cacgatgttg ttaagtttaa
    58381 caatcggtgt ttgaccgatt aattcagtaa tgttgttata aatagacata tgaatacctc
    58441 tttgtataag atatctttag tataacgcta tctataccat ttgtaaaata tagaaatcct
    58501 atcgaagcga taggatttct atatatcata gatcaaagtc attaattttc aagtgattgc
    58561 gttcagctaa ttctagtaaa taggtgtgaa ggaaaacgat atcaggtttc gtttgaattg
    58621 cttcattttc tagtatattt tggtacgcat ctttttattt tgctcgctaa agtagttgtg
    58681 agaatgtcaa cgaaacgctg tattattcat tgtttacact aagtttacag gaacttcaac
    58741 ctctcgtaaa ccttggtcag ttaaagtgac ttttccatta aaaaactcca caagtgcagc
    58801 tttaatagtt tctttttctt ccttatcaac ataaatcatc gtatcgactt gatctgtaaa
    58861 gtttgtatcc agctccatga gatcatgttc tttaaggaag ttactgtact cttggtactg
    58921 agcataagac atttgaatag caatgccagc ctgttctttt atttcaataa taccaatttc
    58981 tttgacagct aaggcgacac tgccggcgta agcacgaatt agtcctccag cgcctagttt
    59041 aataccacca aagtagcgtg tcacgaccac acagacattg gtgagattgt gattttctag
    59101 taccccaagc atgggaacac cagcagtacc actaggctca ccatcatcac ttgtacgttt
    59161 aatttcacta cgttctccaa taataaaggc agagcagtta tgtgtcgctt tgtagtgttc
    59221 ttttttgatg gcagtaatga agtcacgagc ctcttcttcg ctataaacac gcttggcatg
    59281 gcagataaag cgagattttt tgatttcttc ttggacttgg ccgtcctctt taattgtcct
    59341 aaattccatg atttaattgt actaaaaaat aatctaaagt gctagttttt acgaataaag
    59401 aagtatgaaa gtaaatttag attatctcgg tcgtttattt actgagaatg aattaacaga
    59461 agaagaacgt cagttggcgg agaaacttcc agcaatgaga aaggagaagg ggaaactttt
    59521 ctgtcaacgc tgtaatagta ctattctaga agaatggtat ttgcccatcg gtgcttacta
    59581 ttgtcgagag tgcttgctga tgaagcgagt cagaagtgat caaactttat actattttcc
    59641 gcaggaggat tttccgaagc aagatgttct caaatggcgc ggccaattaa ctccttttca
    59701 agagaaggtg tcagagggac tgcttcaagc agtagacaag cagaagccaa ccttagttca
    59761 tgcggtaaca ggagctggaa agacagaaat gatttatcaa gtagtggcta aagtgatcaa
    59821 tgcgggtggt gcagtgtgtt tggctagtcc tcgcatagat gtttgtttgg agctgtacaa
    59881 gcgcctgcaa caggattttt cttgcggtat agctttgcta catggagaat cggaacctta
    59941 ttttcgaaca ccactagttg ttgcaacaac ccatcagtta ttgaagtttt atcaagcttt
    60001 tgatttgctg atagtggatg aagtagatgc ttttccttat gttgataatc ccacgcttta
    60061 ccacgctgtc aagaatagtg taaaggagaa tggattgaga atctttttaa cagcgacttc
    60121 gaccaatgag ttagataaaa aggtccgttt aggagaacta aaaagactga gtttaccgag
    60181 acggtttcat ggaaatccgt tgattattcc aaaaccaatt tggttatcgg attttaatcg
    60241 ctacttagac aagaatcgtt tgtcaccaaa gttaaagtcc tatattgaga agcagagaaa
    60301 gacagcttat ccgttactca tttttgcttc ggaaattaag aaaggggagc agttagaaga
    60361 aatcttacag gagcaatttc caaatgagaa aattggcttt gtatcttctg taacagagga
    60421 tcgattagag caagtacaag cttttcgaga tggagaactg acaatactta tcagtacgac
    60481 aatcttggag cgtggagtta ccttcccttg tgtggatgtt ttcgtaatag aggccaatca
    60541 tcgtttgttt accaagtcta gtttgattca gattggtgga cgagttggac gaagcatgga
    60601 tagaccgaca ggagatttgc ttttcttcca tgatgggtta aatgcttcaa tcaagaaggc
    60661 gattaaggaa attcagatga tgaataagga ggctggtcta tgaagtgctt gttatgtggg
    60721 cagactatga agactgtttt aacttttagt agtctcttac ttctgaggaa tgatgactct
    60781 tgtctttgtt cagactgtga ttctactttt gaaagaattg gggaagagaa ctgtccaaat
    60841 tgtatgaaaa cagagttgtc aacaaagtgt caagattgtc aactttggtg taaagaagga
    60901 gttgaagtca gtcatagagc gatttttact tacaatcaag ctatgaagga ttttttcagt
    60961 cggtataagt ttgatggaga cttcctgtta agaaaagttt tcgcttcatt tttaagtgag
    61021 gagttgaaaa agtacaaaga gtatcaattt gttgtaattc ccctaagtcc tgatagatat
    61081 gctaacagag gatttaatca ggttgagggc ttggtagagg cagcaggctt tgagtatcta
    61141 gatttattag agaaaagaga agagagagcc agttcttcta aaaatcgttc agagcgcttg
    61201 gggacagaac ttcctttctt tattaaaagt ggagtcacta ttcctaaaaa aatcctactt
    61261 atagatgata tctatactac aggagcaact ataaatcgtg ttaagaaact gttggaagaa
    61321 gccggtgcta aggatgtaaa aacattttcc cttgtaagat gaggaaaaaa tttgcaaaaa
    61381 tagaatgaaa gcgttataat aaaatcataa aaacaaaaat gtttagaaag aaggtattca
    61441 tatgattaaa tatagtatcc gtggtgaaaa cctagaagta acagaagcaa ttcgtgatta
    61501 tgtagtttct aaactcgaaa agatcgaaaa gtacttccaa ccagaacaag agttggatgc
    61561 ccgaattaac ttaaaagttt atcgtgaaaa aacggctaaa gtggaagtaa cgattccgct
    61621 tggatctatt actctccgcg cagaagatgt atctcaagat atgtatggtt caattgacct
    61681 tgtaactgat aaaattgaac gtcagattcg taaaaataaa acaaaaatcg agcgtaaaaa
    61741 taaaaataag gtagcaactg gtcaattatt tacagatgct ttggtggaag attcaaatgt
    61801 tgtccagtct aaagttgttc gttcaaaaca aattgattta aaaccaatgg atttggaaga
    61861 agcaattcta caaatggatt tattggggca tgatttcttt atctatgtgg atgttgaaga
    61921 tcagacaacc aatgtgattt atcgtcgtga ggatggcgaa attggtttgt tagaggttaa
    61981 agaatcttaa tttcaatatg tgtaaaggta ggtttactga attgtaaact acctttttct
    62041 tataattgat agaattactg attacacctt taaaaagtcg ctttttgagg ggtattatgg
    62101 tataatgggt gccaagaggt tttgaatgaa aaaattttat gtaagtccaa tttttcctat
    62161 tctagtagga ttgattgcgt ttggagtctt atccactttc attatttttg ttaataataa
    62221 tctgttgacg gttttaattt tgtttctttt tgtaggaggc tatgtttttt tatttaagaa
    62281 actgagagtg cattatacaa ggagtgatgt agaacagata cagtatgtaa accaccaagc
    62341 ggaagaaagt ttgacatctc tattggaaca aatgcctgta ggtgttatga aattgaattt
    62401 atcttctgga gaggttgagt ggtttaatcc ctatgctgaa ttgattttga ccaaggaaga
    62461 tggtgatttt gatttagaag ctgttcaaac gattatcaag gcttcagtag gaaatccgtc
    62521 tacttatgcc aagcttggtg agaagcgtta tgctgttcat atggatgctt cttccggtgt
    62581 tttgtatttt gtagatgtat ccagggaaca agccataaca gatgaattgg taacaagtcg
    62641 accagtgatt gggattgtct ctgtggataa ttatgatgat ttggaggatg caacttctga
    62701 gtcagatatt agtcaaatca atagttttgt agctaatttt atatcagagt tttcagaaaa
    62761 atacatgatg ttttctcgtc gggtaagtat ggatcgattt tatctattta ctgactacac
    62821 ggtgcttgag ggcttgatga atgataaatt ttctgttatt gatgctttca gagaagagtc
    62881 gaaacagaga cagttgccct tgaccttaag tatgggattt tcttatggcg atggaaatca
    62941 tgatgagata gggaaagttg ctttgctcaa tttgaacttg gctgaagtac gtggtggcga
    63001 ccaggtggtt gttaaggaaa acgacgaaac gaaaaatcca gtttattttg gtggtgggtc
    63061 tgctgcttca atcaagcgta cacggactcg tacgcgcgct atgatgacag ctatttcaga
    63121 taagattcgg agtgtagatc aggtttttgt agtcggtcac aaaaatttag acatggatgc
    63181 tttgggctct gctgtaggta tgcagttgtt cgccagcaat gtgattgaaa atagctatgc
    63241 tctttatgat gaagaacaaa tgtctccaga tattgaacga gctgtttcat tcatagaaaa
    63301 agaaggagtt acgaagttgt tgtctgttaa ggatgcaatg gggatggtga ccaatcgttc
    63361 tttgttgatt cttgtagacc attcaaagac agccttaaca ttatcaaaag aattttatga
    63421 tttatttacc caaaccattg ttattgacca ccatagaagg gatcaggatt ttccagataa
    63481 tgcagtcatt acttatatcg aaagtggtgc aagtagtgcc agtgagttgg taacggaatt
    63541 gattcagttc cagaattcta agaaaaatcg tttgagtcgt atgcaagcaa gtgttttgat
    63601 ggctggtatg atgttggata ctaaaaattt cacctcgcga gtaactagtc ggacatttga
    63661 tgttgctagc tatctcagaa cgcgcggaag tgatagtatt gctatccagg aaatcgctgc
    63721 gacagatttt gaagaatatc gtgaggtcaa tgaacttatt ttacaggggc gtaaattagg
    63781 ttcagatgta ctaatagcag aggctaagga cacgaaatgc tatgatacag ttgttattag
    63841 taaggcagca gatgccatgt tagccatgtc aggtattgaa gcgagttttg ttcttgcgaa
    63901 gaatatacaa ggatttatct ctatctcagc tcgaagtcgt agtaaactga atgtacaacg
    63961 gattatggaa gagttaggcg gtggaggcca ctttaatttg gcagcagctc aaattaaaga
    64021 tgtaaccttg tcagaagcag gtgaaaaact gacagaaatt gtattaaatg aaataaagga
    64081 aaaggagaaa gaagaatgaa agtaatcttt ttagcagatg ttaaaggaaa aggtaaaaaa
    64141 ggcgaaatta aggaagtacc aacagggtat gcgcaaaatt ttcttatcaa aaagaatcta
    64201 gccaaagaag cgactgctca agctgtaggt gaacttcgtg gtaaacaaaa atcggaagaa
    64261 aaagctcacg ctgagatgat tgcagaagga aaagcaatta aagcacaact tgaagcagaa
    64321 gaaactgttg tagaatttgt tgaaaaagtt ggtccagatg gtcgtacctt tggttctatt
    64381 accaataaga agattgcaga agaattgcaa aagcaatttg gaattaagat tgataaacgt
    64441 catattcaag tacaagctcc gattcgagcg gttggtttga ttgatgtgcc agtgaaaatc
    64501 tatcaagata tcacaagtgt aatcaatctt cgtgtgaaag aaggataagt ttacaccttc
    64561 ttgacaagat tgtaaaagga agggaagtct gatggcagaa gtagaagagt tacgagtaca
    64621 acctcaagat atcttagctg agcaatccgt tttaggggct atctttattg atgagagtaa
    64681 acttgttttt gtgcgagaat acattgagtc tcgggacttt tttaagtatg cccatcgttt
    64741 gattttccaa gccatggtcg atttatccga tcgtggtgat gccatagatg caacaacggt
    64801 tcgtactatc cttgataatc aaggtgattt acagaatatt ggtggcttgt cttacttggt
    64861 tgagattgtt aattctgtgc caacttctgc taatgcggag tattatgcta agattgttgc
    64921 agaaaaagca atgctacgtc gtttaattgc caagttgaca gagtctgtca accaagctta
    64981 cgaagcgtca caaccagctg atgaaattat tgctcaggca gaaaaagggt tgattgatgt
    65041 cagtgaaaat gcaaatcgaa gcgggtttaa gaacattcga gatgtgttga atctcaactt
    65101 tggaaatctg gaagctcgct cgcaacaaac gaccgatatt acaggtattg cgacaggtta
    65161 tcgtgatttg gatcatatga caacaggact tcatgaggag gagttgatta tcttagcagc
    65221 tcgtccagca gttggtaaga cagcatttgc cttgaatatc gctcagaata ttgggactaa
    65281 gttggacaaa acggttgcta ttttttcact cgaaatgggt gcggaaagct tggtagaccg
    65341 tatgttagct gcagaaggct tggtggagtc acattctatc cgtacagggc aattgacaga
    65401 tgaggagtgg caaaaatata ctattgctca gggtaatcta gctaacgcca gtatctatat
    65461 cgatgatacg ccaggtattc ggattacaga gattcgttct cgttctcgta aattggctca
    65521 agaaactgga aatcttggtt tgattttgat agactatttg caacttatca cgggaactgg
    65581 tcgagaaaat cgtcaacaag aagtttctga aatttctcgt cagttgaaaa tactagccaa
    65641 ggaattgaag gttccagtaa tcgctctgag tcagctttct cgtggtgtag aacaacgtca
    65701 ggacaagaga ccggtcttgt ctgatattcg tgaatctggg tctattgagc aggacgctga
    65761 tatcgtagct tttctctatc gcgatgacta ctatgaacgt ggtggtgaag aagaggaggg
    65821 tatcccaaat aataaggtgg aagttattat cgagaaaaac cgtagtggag ctcgtggaac
    65881 agtggaattg attttccaaa aagaatacaa taaattttca agtatctcaa agagggaggc
    65941 ataagatgtc agatgcattt acagatgtag ccaagatgaa aaaaatcaaa gaagaaatca
    66001 aggcacatga gggacaagtc gtagaaatga ctttggagaa tggtcgtaag cgccaaaaaa
    66061 atagattggg taagctaatt gaagtttatc catccctatt tattgtggag tttggggatg
    66121 tggaaggaga taaacaagtt aatgtttacg ttgaatcctt tacttactca gatattctta
    66181 cagaaaagaa tttgattcat tatcttgact aaagtgagaa attttctcac tttttctttt
    66241 ttctccgaat aatttaggtg aaggcaatca tcgctttata ttatttttca aggaggaaga
    66301 atgaaaattt taccgtttat agcaagagga acaagttatt acttgaagat gtcagttaaa
    66361 aagcttgttc cttttttagt agtaggattg atgctagcag ctggtgatag tgtctatgcc
    66421 tattccagag gaaatggatc gattgcgcgt ggggatgatt atcctgctta ttataaaaat
    66481 gggagccagg agattgatca gtggcgcatg tattctcgtc agtgtacttc ttttgtagcc
    66541 tttcgtttga gtaatgtcaa tggttttgaa attccggcag cttatggaaa tgcgaatgaa
    66601 tggggacatc gtgctcgtcg ggaaggttat cgtgtagata atacaccgac gattggttcc
    66661 attacttggt ctactgcagg aacttatggt catgttgcct gggtgtcaaa tgtaatggga
    66721 gatcagattg agattgagga atataactat ggttatacag aatcctataa taaacgagtt
    66781 ataaaagcaa acacgatgac aggatttatt cattttaaag atttggatgg tggcagtgtt
    66841 gggaatagtc aatcctcaac ttcaacaggc ggaactcatt attttaagac caagtctgct
    66901 attaaaactg aacccctagt tagtgcaact gtgattgatt actattatcc tggagagaag
    66961 gttcattatg atcagatact tgaaaaagac ggctataagt ggttgagtta tactgcctat
    67021 aatggaagct atcgttatgt tcaattggag gctgtgaata aaaatcctct aggtcattct
    67081 gttctttctt caacaggagg aactcattat tttaagacca agtctgctat caaaactgaa
    67141 cccctagtta gtgcaactgt gattgattac tattatcctg gagagaaggt tcattatgat
    67201 cagatacttg aaaaagacgg ctacaagtgg ttgagttata cggcttataa cggaagtcgt
    67261 cgctatatac agctagaggg agtgacttct tcacaaaatt atcagaatca atcaggaaat
    67321 atctctagct atggatccaa taatagttca actgtcggtt ggaagaaaat aaatggtagt
    67381 tggtatcatt tcaaatcaaa tggttctaaa tcaacaggat ggctgaaaga cggttctagc
    67441 tggtattatt tgaaattatc tggtgaaatg cagacaggat ggttaaagga gaatggctcg
    67501 tggtattatc tgggtagttc aggggcaatg aaaacaggct ggtaccaggt ctctggtaag
    67561 tggtattatt cttactcttc aggcgcctta gctgttaata cgacggtgga tggctacaga
    67621 gtaaacagtg atggagaacg agtatagaaa attggagtag gagaaatttc ctgctctttt
    67681 ctgtaagcag tttccttgac atttttctta ttttgcgcta tcatatatac atataatata
    67741 tgggagtctg tgtacagtct gagaggaagt gttaaacttc gaccgcacct gatctgggta
    67801 atgccagcgg agggaacgat acttagtcta attttgcacc ttttccatgt atggtaaagg
    67861 tttttctttt ttttttaaaa ggaaaacgag aagaggaggt tcttatgaaa gcaagcattg
    67921 ccttgcaagt tttaccccta gcacagggga ttgatcggat agctgttatt gatcaggtca
    67981 ttgcttatct gcaaactcaa gaagtgacga tggtagtgac accatttgaa acggtcttgg
    68041 aaggggagtt tgatgagctt atgcgcattc taaaagaagc gctggaagtg gcagggcagg
    68101 aggcagacaa tgtctttgcc aatgtcaaaa taaatgtagg agagatttta agtattgatg
    68161 agaaacttga gaagtatact gagacgccac attagtctat tgggctttct cggagtcttg
    68221 tcaatctggc agttagcagg ttttcttaaa cttctcccca agtttatcct gccgacacct
    68281 cttgaaattc tccagccctt tgttcgtgac agagaatttc tctggcacca tagctgggcg
    68341 accttgagag tggctttact ggggctgatt ttgggagttt tgattgcctg tcttatggct
    68401 gtgctcatgg atagtttgac ttggctcaat gacctgattt accctatgat ggtggtcatt
    68461 cagaccattc cgaccattgc catagctcct atcctggtct tgtggctagg ttatgggatt
    68521 ttgcccaaga ttgtcttgat tatcttaacg acaacctttc ccatcatcgt tagtattttg
    68581 gacggtttta ggcattgcga caaggatatg ctgaccttgt ttagtctgat gcgggccaag
    68641 ccttggcaaa tcctgtggca ttttaaaatt ccagtcagcc tgccctactt ttatgctggt
    68701 ctgagggtca gtgtctccta cgcttttatc acaacagtgg tatctgagtg gttgggaggc
    68761 tttgaggggc ttggtgttta tatgattcag tccaagaaat tgtttcagta tgataccatg
    68821 ttcgctatta ttattctggt atcgattatc agccttttgg gtatgaagtt ggtcgatatt
    68881 agtgaaaaat atgtgattaa atggaaacgt tcgtagaatt agaatgtttc tgaaaaagaa
    68941 aagaggaaat caaaatgaag aaaacatgga aagtgttttt aacgcttgta acagctcttg
    69001 tagctgttgt gcttgtggcc tgtggtcaag gaactgcttc taaagacaac aaagaggcag
    69061 aacttaagaa ggttgacttt atcctagact ggacaccaaa taccaaccac acagggcttt
    69121 atgttgccaa ggaaaaaggt tatttcaaag aagctggagt ggatgttgat ttgaaattgc
    69181 caccagaaga aagttcttct gacttggtta tcaacggaaa ggcaccattt gcagtgtatt
    69241 tccaagacta catggctaag aaattggaaa aaggagcagg aatcactgcc gttgcagcta
    69301 ttgttgaaca caatacatca ggaatcatct ctcgtaaatc tgataatgta agcagtccaa
    69361 aagacttggt tggtaagaaa tatgggacat ggaatgaccc aactgaactt gctatgttga
    69421 aaaccttggt agaatctcaa ggtggagact ttgagaaggt tgaaaaagta ccaaataacg
    69481 actcaaactc aatcacaccg attgccaatg gcgtctttga tactgcttgg atttactacg
    69541 gttgggatgg tatccttgct aaatctcaag gtgtagatgc taacttcatg tacttgaaag
    69601 actatgtcaa ggagtttgac tactattcac cagttatcat cgcaaacaac gactatctga
    69661 aagataacaa agaagaagct cgcaaagtca tccaagccat caaaaaaggc taccaatatg
    69721 ccatggaaca tccagaagaa gctgcagata ttctcatcaa gaatgcacct gaactcaagg
    69781 aaaaacgtga ctttgtcatc gaatctcaaa aatacttgtc aaaagaatac gcaagcgaca
    69841 aggaaaaatg gggtcaattt gacgcagctc gctggaatgc tttctacaaa tgggataaag
    69901 aaaatggtat ccttaaagaa gacttgacag acaaaggctt caccaacgaa tttgtgaaat
    69961 aatgacagaa attagactag agcacgtcag ttatgcctat ggtcaggaga ggattttaga
    70021 ggatatcaac ctacaggtga cttcaggcga agtggtttcc atcctaggcc caagtggtgt
    70081 tggaaagacc accctcttta atctaatcgc tgggatttta gaagttcagt cagggagaat
    70141 tgtccttgat ggtgaagaaa atcccaaggg gcgcgtgagt tatatgttgc aaaaggatct
    70201 gctcttggag cacaagacgg tgcttggaaa tatcattctg cccctcttga ttcaaaaggt
    70261 ggataaggca gaagctattt cccgagcgga taaaattctt gcgaccttcc agctgacagc
    70321 tgtaagagac aagtatcctc atgaacttag cggtgggatg cgccagcgtg tagccttact
    70381 ccggacctac ctttttgggc acaagctctt tctcttagat gaggccttta gcgccttgga
    70441 tgagatgaca aagatggaac tccacgcttg gtatcttgag attcacaagc agttgcagct
    70501 aacaaccctg atcatcacgc atagtattga ggaggccctc aatctcagcg accgcatcta
    70561 tatcttgaaa aatcgccctg ggcagattgt ttcagaaatt aaactagatt ggtctgaaga
    70621 tgaggacaag gaagtccaaa agattgccta caaacgtcaa atcttggcag aattaggctt
    70681 agataagtag aaaaataggg agttggtgaa gattatcctt taccagcgcc ctttttcttt
    70741 taaaaatgag aaaatttcgg tataatagtc aaacaaggtc aaggtttaaa gagagaggtg
    70801 ggtttgttat aagatttaaa aatacatcgg atcatattga ggcctacatc aaggcgattt
    70861 tagatcaatc tggtatcgtg gagttgcaac ggagtcagtt ggcagatacc tttcaggttg
    70921 ttcctagtca gattaactac gtgatcaaga cacgctttac ggaaagtaga ggctacttgg
    70981 ttgaaagtaa gcgtggtggc ggaggctaca ttcgtatagg acggattgag ttttctagtc
    71041 atcatgaaat gctccgggag ctgctttact cgattggtga gcgagtcagt caagaaattt
    71101 atgaggatat tctccagctt ttggttgagc aggaattgat gaccaagcag gagatgaatt
    71161 tgctagaatc agtagctttg gatcgcgttt taggagaaga agctccagtt gttcgagcaa
    71221 acatgctacg tcagatcata caagaggtag atagaaaagg gaagtaagat gaactattca
    71281 aaagcattga atgaatgtat cgaaagtgcc tacatggttg ctggacattt tggagctcgt
    71341 tatctagagt cttggcactt gttgattgcc atgtctaatc acagttatag tgtagcaggg
    71401 gcaactttaa atgattatcc gtatgagatg gaccgtttag aagaggtggc tttggaactg
    71461 actgaaacgg actatagcca ggatgaaacc tttacggaat tgccgttctc ccgtcgtttg
    71521 caggttcttt ttgacgaagc agagtatgta gcgtcagtgg tccatgctaa ggtgctaggg
    71581 acagagcacg tcctctatgc gattttgcat gatggcaatg ccttggcgac tcgtatcttg
    71641 gagagggctg gtttttctta tgaagacaag aaagatcagg tcaagattgc tgctcttcgt
    71701 cgaaatttag aagaacgggc aggctggact cgtgaagatc tcaaggcttt acgccaacgc
    71761 catcgtacag tagctgacaa gcaaaattct atggccaata tgatgggcat gccgcagact
    71821 cctagtggtg gtctcgagga ctatacgcat gatttgacag agcaagcgcg ttctggcaag
    71881 ttagaaccag tcatcggtcg ggacaaggaa atctcacgta tgattcaaat cttgagccgg
    71941 aagactaaga acaaccctgt cttggttggg gatgctggtg tcgggaaaac agctctggcg
    72001 cttggtcttg ctcagcgtat tgctagtggt gacgtgtctg cggaaatggc taagatgcgc
    72061 gtgttagaac ttgatttgat gaatgtcgtt gcagggacac gcttccgtgg tgactttgaa
    72121 gaacgcatga ataatatcat caaggatatt gaagaagatg gccaagtcat cctctttatc
    72181 gatgaactcc acaccatcat gggttctggt agcgggattg attcgactct ggatgcggcc
    72241 aatatcttga aaccagcctt ggcgcgtgga actttgagaa cggttggtgc cactactcag
    72301 gaagaatatc aaaaacatat cgaaaaagat gcggcacttt ctcgtcgttt cgctaaagtg
    72361 acgattgaag aaccaagtgt ggcagatagt atgactattt tacaaggttt gaaggcgact
    72421 tatgagaaac atcaccgtgt acaaatcaca gatgaagcgg ttgaaacagc ggttaagatg
    72481 gctcatcgtt atttaaccag tcgtcacttg ccagactctg ctatcgacct cttggacgaa
    72541 gcagcagcaa cagtgcaaaa taaggcaaag catgtaaaag cagacgattc agatttgagt
    72601 ccagctgaca aggccctgat ggatggcaag tggaaacagg cagcccagct aatcgcaaaa
    72661 gaagaggaag tacctgtcta caaagacttg gtgacagagt ctgatatttt gaccaccttg
    72721 agtcgcttgt caggaatccc cgttcaaaaa ctgactcaaa cggatgctaa gaagtattta
    72781 aatcttgaag cagaactcca taaacgtgtc atcggtcaag atcaagctgt ttcaagcatt
    72841 agtcgtgcca ttcgccgtaa tcagtcagga attcgcagtc acaagcgtcc gatcggttcc
    72901 tttatgttcc taggacccac aggtgtcggt aagaccgagt tggccaaggc tttggcagaa
    72961 gttctctttg atgacgaatc agcccttatc cgctttgata tgagtgagta tatggagaaa
    73021 ttcgcagcca gccgtctaaa tggagctcct ccaggctatg tgggttacga agaaggtggg
    73081 gagttgacag agaaggttcg caataaaccc tattccgttc tcctctttga tgaggtagag
    73141 aaggctcacc cagatatctt taatgttctc ttgcaggttc tggatgacgg tgtcttgaca
    73201 gatagcaagg gacgcaaggt cgatttttca aataccatta tcattatgac atcgaaccta
    73261 ggtgcgactg cccttcgtga tgataagact gttggttttg gggctaagga tattcgtttt
    73321 gaccaggaaa atatggaaaa acgcatgttt gaagaactga aaaaagctta tagaccggaa
    73381 ttcatcaacc gtattgatga gaaggtggtc ttccatagcc tatctagtga ccatatgcag
    73441 gaagtggtga agattatggt caagccttta gtggcaagtt tggctgaaaa aggcattgac
    73501 ttgaaattac aagcttcagc tctgaaattg ttagcaaatc aaggatatga cccagagatg
    73561 ggagctcgcc cacttcgcag aaccctgcaa acagaagtgg aggacaagtt ggcagaactt
    73621 cttctcaagg gagatttagt ggcaggcagc acacttaaga ttggtgtcaa agcaggccag
    73681 ttaaaatttg atattgcata aaagaataaa agtatcagca tctgaccata agtcacagtg
    73741 gagtgaaact caatgaaaat caaagagcaa actaggcagc tagccgcagg ttgctcaaaa
    73801 cactggtttg aggttgtaga tagagctgac gtggtttgaa gagattttcg aagagtataa
    73861 gctgcaagat gaatgatttt cttgtattga cgttgttgtt gacaaaaagt agcggataaa
    73921 tgaaatccat tccattatca tagatgatag gctggtagga aattttcaaa tagcatatag
    73981 gaaatagatg tatggagttc tggtagtaga aagggagaga gatgaacatt ttagttgcag
    74041 atgacgagga aatgattaga gaaggaattg cagcatttct gacagaagag ggttatcatg
    74101 tcattatggc taaggatgga caagaggtct tggaaaaatt tcaagatctc cctatccatc
    74161 tcatggtact ggatttaatg atgcctagga agagtggttt tgaagtgtta aaagaaatca
    74221 atcaaaagca cgatattcct gtcatcgtct tgagtgctct gggagatgaa actactcagt
    74281 cacaggtatt tgatctctat gctgatgatc atgtgacaaa acctttttct ttggtactgc
    74341 ttgtcaagcg tattaaggcg cttatcagac gttactacgt catagaggat ctttggcgat
    74401 atcaggatgt aacagtggat tttacctctt acaaagcaca ttataaaaat gaagaaattg
    74461 atctcaaacc aaaggaatta ctggtactaa agtgtttgat tcagcataaa aatcaagttt
    74521 taagtagaga gcagatattg gaagaaattt caaaagatgt agctgattta ccttgtgata
    74581 gggtcgttga tgtctatatt cgtactcttc gcaaaaaatt agctttagat tgtatcgtga
    74641 ctgtgaaaaa tgttgggtat aagattagct tatgataaaa aatcctaaat tattaaccaa
    74701 gtctttttta agaagttttg caattctagg tggtgttggt ctagtcattc atatagctat
    74761 ttatttgacc tttccttttt attatattca actggagggg gaaaagttta atgagagcgc
    74821 aagagtgttt acggagtatt taaagactaa gacatctgat gaaattccaa gcttactcca
    74881 gtcttattca aagtccttga ccatatctgc tcaccttaaa agagatattg tagataagcg
    74941 gctccctctt gtgcatgact tggatattaa agatggaaag ctatcaaatt atatcgtgat
    75001 gttagatatg tctgttagta cagcagatgg taaacaggta accgtacaat ttgttcacgg
    75061 ggtggatgtc tacaaagaag caaagaatat tttgcttttg tatctcccat atacattttt
    75121 ggttacaatt gctttttcct ttgttttttc ttatttttat actaaacgct tgctcaatcc
    75181 tcttttttac atttcagaag tgactagtaa aatgcaagat ttggatgaca atattcgttt
    75241 tgatgaaagt aggaaagatg aagttggtga agttggtgaa gttggaaaac agattaatgg
    75301 tatgtatgag cacttgttga aggttattca tgaattggaa agtcgtaatg agcaaattgt
    75361 aaaattgcaa aatcaaaagg tttcctttgt ccgcggagca tcacatgagt tgaaaacccc
    75421 tttagccagt cttagaatta tcctagagaa tatgcagcat aatattggag attacaaaga
    75481 tcatccaaaa tatattgcaa agagtataaa taagattgac cagatgagcc acttattgga
    75541 agaagtactg gagtcttcta aattccaaga gtggacagag tgtcgtgaga ctttgactgt
    75601 taagccagtt ttagtagata ttttatcacg ttatcaagaa ttagctcatt caataggtgt
    75661 tacaattgaa aatcaattga cagatgctac cagggtcgtc atgagtctta gggcattgga
    75721 taaggttttg acaaacctga ttagtaatgc aattaaatat tcagataaaa atgggcgcgt
    75781 aatcatatcc gagcaagatg gctatctctc tatcaaaaat acatgtgcgc ctctaagtga
    75841 ccaagaacta gaacatttat ttgatatatt ctatcattct caaatcgtga cagataagga
    75901 tgaaagttcc ggtttgggtc tttacattgt gaataatatt ttagaaagct atcaaatgga
    75961 ctatagtttt ctcccttatg aacacggtat ggaatttaag attagcttgt agacagatta
    76021 gttttttatt aaagttcata tagggttaac ataagtgtat tattctttat atagataaaa
    76081 atatagataa aagaaaggat actaatatgg tattagcgat tattttagta acattcctta
    76141 ttcgattgat ttttttaaag cgttcgatag agaatgagaa acgaatcctt agcaatggcg
    76201 ggaaagaatt tggagttgag aatacaaaac gattaacgtt ggctcatatt gttttttatc
    76261 tctcttgcct cgttgaagca atggtgcata agacaatgtt tgatggtatg agcatggttg
    76321 gtttagtctt gcttattttt tctatgctga tgttgatgtt ggtgattcac ttgttgggag
    76381 atatttggac agtgaagctt atgcttgtca ataatcacaa atatgtagat catatcttgt
    76441 ttaggacagt aaaacatcct aattactttt taaatatttt acctgagttg attggcttga
    76501 ccttgttgag tcatgcctat atgacttttg ttttagtttt tccagtttat gcagttattt
    76561 tgtatcgacg aatagctgaa gaggaaaagc tattacatga agttataatc ccaaatggaa
    76621 gcataaagag ataaatacaa aattcgattt atatacagtt catattgaag tgatatagta
    76681 aggttaaaga aaaaatatag aaggaaataa acatgtttgc atcaaaaagc gaaagaaaag
    76741 tacattattc aattcgtaaa tttagtattg gagtagctag tgtagtagtt gccagtcttg
    76801 ttatgggaag tgtggttcat gcgacagaga acgagggaag tacccaagca gccacttctt
    76861 ctaatatggc aaagacagaa cataggaaag ctgctaaaca agtcgtcgat gaatatatag
    76921 aaaaaatgtt gagggagatt caattagata gaagaaaaca tacccaaaat ttcgccttca
    76981 acatgaagtt gagcgcaatt aaaacggagt atttgtatgg attaaaagag aagtcggaag
    77041 ctgagttgcc gtcagaagta aaagcaaagt tagacgcagc ttttgagcag tttaaaaaag
    77101 atacattgaa actaggagaa aaggtagcag aagctgagaa gaaggttgca gaagctgaga
    77161 aaaaagccaa ggctcaaaaa gaagaagatc gccgtaacta cccaaccatt acttacaaaa
    77221 cgcttgacct tgaaattgct gagtccgatg tggaagttaa aaaagcggag cttgaactat
    77281 tgaaagagga agctaaaact cgaaacaagg acacaattaa ccaagcaaaa gcgaaagttg
    77341 agagtaaaca agctgaggct acaaggttaa aaaaaatcaa gacagatcgt gaacaagctg
    77401 agactacaag gttagaaaac atcaagacag atcgtaaaaa agcagaagaa gaagctaaag
    77461 ttaaagctaa accaaagaag cggacaaaac gaggagctct tggagagcca gcaacacctg
    77521 ataaaaaaga aaatgatgcg aagtcttcag attctagcgt aggtgaagaa actcttccaa
    77581 gcccatccct gaaaccagga aaaaaggtag cagaagctga gaagaaggtt gaagaagctg
    77641 agaaaaaagc caaggatcaa aaagaagaag atcgccgtaa ttacccaacc attacttaca
    77701 aaacgcttga acttgacatt gctgagtccg atgtggaagt taaaaaagcg gagcttgaac
    77761 tagtaaaaga ggaagctaag gaatctcgag acaaggaaaa aattaagcaa gcaaaagcgg
    77821 aagttgagag taaaaaagct gaggctacaa ggttagaaaa aatcaagaca gatcgtaaaa
    77881 aagcagaaga agaagaagct aaacgaaaag cagcagaaga agataaagtt aaagaaaaac
    77941 cagctgaaca accacaacca gcgccggctc ctcaaccaga aaaaccaact gaagagcctg
    78001 agaatccagc tccagctcca aaaccagaga agccagctga acaaccaaaa gcagaaaaac
    78061 cagctgatca acaagctgaa gaagactatg ctcgtagatc agaagaagaa tataatcgct
    78121 tgactcaaca gcaaccgcca aaaattgaaa aaccagctcc agcaccacaa ccagagcaac
    78181 cagcacaacc atctactcca aaaacaggct ggaaacaaga aaacggtatg tggtacttct
    78241 acaatactga tggttcaatg gcgacaggat ggctccaaaa caatggctca tggtactacc
    78301 tcaacagcaa tggcgctatg gcgacaggat ggctccaaaa caatggttca tggtactatc
    78361 taaacgctaa tggttcaatg gcaacaggat ggctccaaaa caatggttca tggtactacc
    78421 tcaacgctaa tggttcaatg gcgacaggat ggctccaata caatggttca tggtactacc
    78481 tcaacgctaa tggtgatatg gcgacaggat ggttccaata caatggttca tggtactacc
    78541 tcaacgctaa tggtgatatg gcgacaggat ggctccaata caatggttca tggtactacc
    78601 tcaacagcaa tggtgctatg gtaacaggat ggctccaaaa caatggctca tggtactacc
    78661 taaacgctaa tggtgatatg gcgacagatt gggtgaaaga tggagatacc tggtactatc
    78721 ttgaagcatc aggtgctatg aaagcaagcc aatggttcaa agtatcagat aaatggtact
    78781 atgtcaatgg ctcaggtgcc cttgcagtca acacaactgt agatagctat agagtcaata
    78841 ccaatggtga atgggtaaac taaacctaat ataactagtt aatactgact tcctgtaaga
    78901 actctttaaa gtattcccta caaataccat atcctttcag tagataatat acccttgtag
    78961 gaagtttaga ttaaaaaata actctgtaat ctctagccgg atttatagcg ctagagacta
    79021 cggagttttt ttgatgagga aagaatggcg gcattcaaga ggctctttaa gagagttacg
    79081 ggttttaaac tattaagcct tctccaattg caagagggct tcaatctctg ccagggtgct
    79141 agcttgcgaa atggctccac ggagtttggc agcgccagat gttccacgga gatagtgagg
    79201 agcgaggccg cggaattcac gaactgcgac gttttctcct ttgaggtcaa tcaatcgttt
    79261 caagtgttcg taggcgatct tcatcttgtc ttcaaaggtc aaatcaggta ggatttctcc
    79321 tgtttcaaag taatggttga tttggttgaa gaggtaagga tttcccatgg cagctcggcc
    79381 aatcatgact gcgtcagcac caacttcttc gatgcgttgc ttggcttctt gtacagtacg
    79441 gatatcaccg ttggcgatga atggaatctt ggttagagct tgggcaacct tgtaaagggt
    79501 ctcaaggtct gcgtggccag tatacatttg ttcacgggta cggccatgca tggcgagggc
    79561 agaaacacct gcagcttcag cagcgagggc attttctact gccagagatg ggtccgccca
    79621 gccggtacgc attttgacag taagtgggat atcaaggaca gactggacct tgttgatgat
    79681 ggagtaaatc ttgtctggat ccttgagcca catagcacca gcttcgttct tcacgatttt
    79741 gttgacaggg cagcccatgt tgatatcgac gatatcggtc ttggtgtttt cttggataaa
    79801 ttctgctgcg cgtgctaggc tgtcttcatc gctaccaaaa agttggatag agacagggtt
    79861 ttcgccctca tcgatatgaa gcatgtgcag ggttttttcg ttgttgtatt ggattccctt
    79921 gtcagagacc atttccatta caacgagtcc agctccgagc tcttttgcga tggtacgaaa
    79981 ggctgagttg gtcacgccag ccataggcgc taaaacggta cgattgggaa tctcaacatt
    80041 gccaatcata aaaggtgtat taagatttgt cacgaatgag ttcctccagg tccttttcat
    80101 caaagttgta agtagtttgg cagaattgac aagtgatttc taccccgtgg tcttcctctt
    80161 tcatttcctg taagtctgag cttggaaggc tggcaagagc gttcataaag cgttcatggc
    80221 tacagtcaca ttggaaacgg atttcttctt cagaaagacg cttgtaggct tcgtccccgt
    80281 agatagcctt gaggagggct tcgatatggt cgtcgctttc gagaagagta gagatagctg
    80341 gcatttcttg gatgcgtttt tcaaagcgag caatctcttc tttcttggct cctggcaaga
    80401 cttgaactag gaaaccacct gcaaccttga ccttgtcttc ctcgtccaaa aggacattga
    80461 ggccgaccgc tgaaggcgtt tgttggcttt cagtaaggta aaaggcaagg tcttcaccga
    80521 tttctccaga gatgagggga gttatagagt tgtaaggatt tccagtaccg tagtctgtga
    80581 taacgaggaa ttgaccattt ccaacaaaag gtccgactag gacttcacca gtcgcagtct
    80641 ttttgatgtc aacaccagga ttttgaacat agcctttgac gttccccttg gtatcagcga
    80701 cggtgataat agcacctaga gagctagagc ccaacacctt aactgtaagt ttggtatttc
    80761 ctttttcatt ggctgcgaga atctggctgg cgataagagt tcgaccaagc gctacagttg
    80821 agctagcttg ggtttgatgt ttttcttgag cagtgcggac ggtttccgtg ctatcaagga
    80881 caaaagcacg aaaggctccg ctttctgata tagttttaat aattttatcc atagctacta
    80941 ttttagcata aaaatgccca aagggggagc cgtgtgttta ctgattttca ggataatgga
    81001 ccaggaaatc agcatgaaaa taaaaagaga aacagattat tttagcattt gtaagattta
    81061 tgctatgctt aaggtagaaa atgaaagggg taacaaatgt atttaggaga tttgatggag
    81121 aaagccgagt gtggtcaatt ttcaatcctt tcctttctat tacaagagtc tcagacgacc
    81181 gtcaaggctg taatggaaga aacaggattt tcaaaagcaa ccctaaccaa atatgtcacc
    81241 ctgctcaatg acaaggcttt ggatagtggc ttagagctga ctattcactc agaagatgaa
    81301 aatctgcgtc tgtctatcgg tgcagctacc aaggggagag atattcggag cttgtttttg
    81361 gagagtgctg ttaaatacca gattttggtt tatcttctct accaccaaca gtttttagcc
    81421 catcagctgg ctcaagaatt ggtgattagc gaggctacgc ttggtcgtca cttggctggt
    81481 ttaaatcaga ttttgtcaga atttgattta tccatccaaa atggacgttg gcgaggtcca
    81541 gagcatcaga ttcgctattt ctatttctgt cttttccgaa aggtctggtc gagtcaggaa
    81601 tgggaaggtc acatgcagaa accagagaga aaacaggaga ttgccaattt agaggaaatc
    81661 tgcggtgcaa gtttgtctgt ggggcagaaa ttggacttgg ttctctgggc tcacatcagt
    81721 caacaacgtc ttcgggtcaa tgcttgtcag tttcaagtca tagaagagaa aatgcgaggg
    81781 tattttgaca atatctttta tcttcgtttg ctgagaaagg ttccgtcctt ttttgctggg
    81841 caacatattc cactaggagt tgaggatggt gagatgatga tattcttctc ttttctccta
    81901 tctcatcgca ttcttcctct tcatactatg gagtatattc ttggttttgg agggcagttg
    81961 gcagatttac tgacgcaatt gattcaagaa atgaagaagg aggaactatt gggggattat
    82021 acagaggacc atgtcaccta tgaactcagt cagctttgtg ctcaagtcta tctctataag
    82081 ggctatattt tacaggatcg ctacaagtac cagttagaga atcgtcatcc atatttactg
    82141 atggaacatg attttaaaga gacagcagag gagatttttc atgctctacc tgcttttcaa
    82201 caggggacag atttagataa gaagattctc tgggaatggc tccagttaat cgaatatatg
    82261 gctgaaaacg gtggtcagca tatgcggatt ggtctggatt tgacatctgg ttttcttgtc
    82321 ttttcaagga tggcagccat tttgaaacgg tatttggaat acaatcgttt tattaccatt
    82381 gaagcttatg accctagtcg gcattatgat ttgctggtta ccaataaccc gattcataag
    82441 aaggaacaga caccagtcta ttatttaaaa aacgacttgg atatggaaga tttggcaggg
    82501 attcgtcagt tattattcac ttaaaaggct tggttaatcc aggtcttttt tgtgaaattc
    82561 acacaatctc ctcacatttt tttaaaaatt aaaaaaagtt gataaacaag aaagcgcttt
    82621 attttgtata ctagtaagtg taaagaggaa acacctcaag atctttatca ggaggacagt
    82681 acatgtcaca agaaaaatac atcatggcca ttgaccaggg aactacaagt tctcgtgcca
    82741 tcattttcaa caaaaaaggg gaaaaggtta gctcgagtca aaaagagttt acccagattt
    82801 tccctcaggc aggttgggtt gagcacaatg ccaatgaaat ttggaactct gttcagtcag
    82861 ttattgcggg tgctttcatc gaaagtggtg tcaagccaaa tcaaatcgag gcaatcggga
    82921 ttaccaacca acgtgaaaca acggttgtct gggataagaa aacaggactt cctatctaca
    82981 atgctatcgt ttggcagtca cgccagacag cacctttggc tgagcaacta aaaagccaag
    83041 gttatgtgga aaaattccat gaaaagactg gtttgattat tgatgcttac ttctctgcta
    83101 ccaaggttcg ttggattttg gatcatgtag aaggcgctca agagcgagca gaaaaagggg
    83161 aattgctctt tggtactatc gatacttggt tggtttggaa attgactgac ggtgcggctc
    83221 acgtgactga ctactcaaat gcagctcgta ccatgcttta taacattaaa gaactcaaat
    83281 gggatgatga gattttggaa atccttaaca ttccgaaggc tatacttcca gaagttcgtt
    83341 ctaactccga aatctacggc aagacagctc cattccattt ctacggtgga gaggtgccaa
    83401 tctcaggtat ggctggggac caacaagcag ccctctttgg acagttggct tttgagccag
    83461 gtatggttaa gaatacttat ggaacaggct ctttcatcat catgaatact ggggaagaga
    83521 tgcagttgtc tgaaaacaac ctcttgacaa ccattggtta cggaatcaac ggtaaggttt
    83581 attatgcctt ggaaggttct atcttcatcg caggaagtgc tattcagtgg cttcgtgacg
    83641 gtcttcgcat ggttgaaaat tcaccagaat ctgaaaaata cgctcgtgat tctcacaaca
    83701 acgatgaagt ttatgtcgtt ccagccttta caggtctagg cgctccatac tggaaccaaa
    83761 atgctcgtgg ttccgtcttt ggtttgactc gtggaacaag caaagaagac tttatcaagg
    83821 cgactttgca atctattgct tatcaagtgc gtgacatcat cgacaccatg caagtggata
    83881 ctcagaccgc cattcaagta ttgaaggtgg atggtggtgc agccatgaac aacttcctca
    83941 tgcagttcca ggcggatatt ttaggcattg atattgcacg tgctaaaaac ctggaaacaa
    84001 cagctctagg agcggccttc ctagcaggtt tgtcagtagg gtactggaaa gacttggacg
    84061 agttgaaact cttgaacgag acaggagaac tctttgagcc atctatgaac gaatctcgca
    84121 aggaacaact ctacaagggc tggaagaagg ctgtgaaagc aactcaagtc tttgcggaag
    84181 tagacgacta atactggcag aataaagcga tttatttaga aagtgtgtaa atatggaatt
    84241 ttcaaagaaa acacgtgaat tgtcaattaa aaaaatgcag gaacgcaccc tggacctctt
    84301 gattatcggt ggaggaatca caggagctgg tgtagccttg caggcggcag ctagcggtct
    84361 tgagactggt ttgattgaaa tgcaagactt tgcagaagga acatctagtc gttcaacaaa
    84421 attggttcac ggaggtcttc gctacctcaa acaatttgac gtagaggtgg tctcagatac
    84481 ggtttctgaa cgtgcagtgg ttcaacaaat cgctccacac attccaaaac cagatccaat
    84541 gctcttacca gtttacgatg aagatggagc aacctttagc ctcttccgtc ttaaagtagc
    84601 catggacttg tacgaccttt tagcaggtgt gagcaacaca ccaactgcga acaaggtttt
    84661 gagcaaggat caagtcttgg aacgccagcc aaacttgaag aaggaaggct tggtaggagg
    84721 tggagtgtat cttgacttcc gtaacaacga tgcgcgtctc gtgattgaaa acatcaaacg
    84781 tgccaaccaa gacggtgccc tcattgccaa ccacgtgaag gcagaaggct tcctctttga
    84841 cgaaagtggc aagattacag gtgttgtagc tcgtgatctc ttgacagacc aagtatttga
    84901 aatcaaggcc cgtctggtta ttaatacaac aggtccttgg agtgataaag tacgtaattt
    84961 gtctaataag ggaacgcaat tctcacaaat gcgcccaact aagggagttc acttggtagt
    85021 ggattcaagc aaaatcaagg tttcacagcc agtttacttt gacacaggtt tgggtgacgg
    85081 tcgtatggtc tttgttctcc cacgtgaaaa caagacttac tttggtacaa ctgatacaga
    85141 ctacacaggt gatttggagc atccaaaagt aactcaagaa gatgtagatt atctacttgg
    85201 cattgtcaac aaccgctttc cagaatccaa catcaccatt gatgatatcg aaagcagctg
    85261 ggcaggtctt cgtccattga ttgcagggaa cagtgcctct gactataatg gtggaaataa
    85321 cggtaccatc agtgatgaaa gctttgacaa cttgattgcg actgttgaat cttatctctc
    85381 caaagaaaaa acacgtgaag atgttgagtc tgctgtcagc aagcttgaaa gtagcacatc
    85441 tgagaaatat ttggatccat ctgcagtttc tcgtgggtct agcttggacc gtgatgacaa
    85501 tggtcttttg actcttgctg gtggtaaaat cacagactac cgtaagatgg ctgaaggagc
    85561 tatggagcgc gtggttgaca tcctcaaagc agaatttgac cgtagcttta aattgatcaa
    85621 ttctaaaact taccctgttt caggtggaga attgaaccca gcaaatgtgg attcagaaat
    85681 cgaagccttt gcgcaacttg gagtttcacg tggtttggat agcaaggaag ctcattacct
    85741 agcaaatctt tatggttcaa atgcaccgaa ggtctttgca cttgctcaca gcttggaaca
    85801 agcgccaggt cttagcttag cagacacctt gtctcttcac tatgcaatgc gcaatgagtt
    85861 gactcttagc ccagttgact tccttcttcg tcgtaccaat cacatgctct ttatgcgtga
    85921 tagcttggat agtatcgttg agccagtttt ggatgaaatg ggacgattct atgactggac
    85981 agaagaagaa aaagcaactt accgtgctga tgtaaaagca gctcttgctc aaaacgactt
    86041 agcagaatta aaaaattaag aaaaaataaa agaggtggag ggtagcaatc cttgtcgccc
    86101 gccccttttt taatggagac agaaaaatga tgagtgaatt atttggagaa tttttaggga
    86161 ctttaatcct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt ccaaaaacca
    86221 agagcaacag tgcaggttgg attgtgatta ctatgggttg ggggattgca gttgcggttg
    86281 cagtatttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg accatcggtg
    86341 tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta gcccagttcg
    86401 caggggccat gctgggtcag attttggttt ggttgcaatt caaaccgcat tatgaggtag
    86461 aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc aaggatactg
    86521 tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca atctttgctt
    86581 tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact ttgattgtcg
    86641 gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct cgtgaccttg
    86701 gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga gactggtctt
    86761 acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg cttgtattct
    86821 cacttttcta gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg tcgccttacc
    86881 gtactcaagt acagcttgcg gctagcttcc tagtttgctc tttgattttc attgagtatt
    86941 agaaaacaat tattttgata gagcttgggc aagagcccaa tttcagcaaa aaatgaagta
    87001 aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg tcaactacag
    87061 tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc aagcacctgc
    87121 aagcaacgtg ccgaaatggt caaatcctga ttatgtcaac gaattagacc caaaaatcgt
    87181 tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg aggcgcaagc
    87241 agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg agggtaaaaa
    87301 acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc ttacaaatta
    87361 cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt ttatatttta
    87421 gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt ttctatagta
    87481 ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg ttatgtagta
    87541 tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa aatatgctcc
    87601 accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa tcatataact
    87661 gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc catgtattgt
    87721 gttgacgtaa ttccaaacat taggatcgta tgatctaaaa gatatattta ggtcgatttc
    87781 attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag cacgtcgttc
    87841 aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc ttaaaatatt
    87901 tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct caccagatac
    87961 aactttagag tttgccgata agctatcatc agcaaaaaca aacaagcgac ggggaaatgc
    88021 tagacataca gaaaacagac ataactagca aacacatgca tttaaacatc ttagacataa
    88081 cggaaactcc tttgtatttt tgattttttt caacttttat tatacaataa aaccaaataa
    88141 aaagaaagcg gtaacaatat gcttaatgcg aaaatttttt atatattttt atgtttgatc
    88201 gttatcgaaa ctacaggctt gttgttgttg aaaagaggtc tcgaaatggg ttatttagac
    88261 acagaagcta ttatcctcgc agttttttca tttgcttttt acaacctatg ttcattcgct
    88321 tgggtctgct ctacaataaa aaacaataaa aaataaatag acgtattttc aaaaaaaaaa
    88381 aaaatgcata tttatcttag caaaacgacg atttaaatcg tcgttttttt gtagtacgac
    88441 gggcatgtcg tatatctgag gtgtaagtcc tcggtgggca cctgctaccg gtgaacccaa
    88501 tagcgattcc caagcctgac tatcgtgagg tagcggatta aaacggtctg gggatagacc
    88561 gttttaagtc tgacgcagga aataagaatc gtcagaggaa gagatagcga aatcgtggct
    88621 ctacgaacag gaacgtgata gcaaggcgta tatagcggat aaggaggctt caaactctaa
    88681 agtccaaaaa ggtagtcgta acctatatgt gtaaatcacg agagtaattg aattcggact
    88741 aaggtttgtg tgaaaaagat aaatctttct agagtctaaa gactctgcgt cagatttcct
    88801 attttcactg taacctttta acgtcctcat atcttgtata aacgaggaaa gatgtacgac
    88861 ttatcccgtg aggtttcatg agcgctgaaa gcgtagtaac aacgaatcat gagaagtcag
    88921 ccgagcccat agtagtgagg aaacttccgt aatggaagtg gagcgaaggg gtgaatactc
    88981 aaacagtctg gggagagact gtttgaggtc tgtcgctaga aagagaaaac gacagatcga
    89041 agtaatccta cttcacttgt gtctgtaaaa tgagtggtct gatagaactg gactttgaca
    89101 cgtaatgact agatgaaggt tcaccaatat aagatgtccc tcaggcacca aaacaagaaa
    89161 ggaatacgca catgtcaaaa ttgctagata agatattatc acgcgaaaat atgctggaag
    89221 cctacaatca agtaaaatcc aataaaggct cagctgggat tgatggaatg actatcgaag
    89281 agatggataa ttatctcaga caaaactggc gcttgactaa ggaactgata aaacagagaa
    89341 aatataagcc tcaaccagtt cttagagttg agattactaa accaaacgga ggtatccgtc
    89401 aactaggaat tccaacagtt atggatagaa tgattcaaca ggccattgtc caagttatta
    89461 gccccatttg tgaaccccat ttctcagata cgagttatgg cttcagacca aataggtcat
    89521 gtgaaaaagc catcatgaag ttcttagagt acttaaatga cggctatgag tggatagtgg
    89581 atatagacct agagaaattt ttcgatacgg ttcctcaaga tagattgatg tccttggtac
    89641 ataacattat cgaagacgga gatacggaat ccctgattcg taagtatctt cattcaggtg
    89701 ttatcattaa tggtcagcgt cataaaacgc tagttggcac gccacaggga ggaaatttat
    89761 ctcctctctt atccaatgtc atgcttaatg aattggacaa ggaattagaa aagaggggac
    89821 ttcgatttgt gcgctacgca gatgattgtg tgattacggt cggaagcgag gcagccgcta
    89881 agcgtgtgat gtattcagcc agtcgtttta ttgagaagcg actaggtttg aaagtaaata
    89941 tgaccaaggc taagattacc agaccaagag agctgaaata cttaggtttt gggttctgga
    90001 aatcatcaga tggttggaaa agtcgtcccc atcaagatag tgttcggaga tttaagctta
    90061 aattgaagaa actaacacag aggaaatgga gtatagactt aacaagacgt attgagcaac
    90121 tgaatttgtc tattcgagga tggataaact atttctcgct gggaaatatg aagcgcatag
    90181 tcgctagcat agatgagcgc ttgcgtactc gcctacgagt gattatctgg aagcaatgga
    90241 agaagaaatc gagacgacta tggggattgc ttaagttagg agttcctaaa tggatagcag
    90301 ataaggtatc tggctggggc gaccattatc aa
//
LOCUS       DAVLMQ010000004        75168 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000004 DAVLMQ010000000
VERSION     DAVLMQ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 75168)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 75168)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..75168
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.004"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            186..1667
                     /locus_tag="VXF95_000331"
     CDS             186..1667
                     /locus_tag="VXF95_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1080934.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSS
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            2029..3030
                     /locus_tag="VXF95_000332"
     CDS             2029..3030
                     /locus_tag="VXF95_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1080935.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLKKVEQ
                     AIKTLNYIPDYYARGMKKNRTETIAIIVPSIWHPFFSEFAMHVENEVYKRNNKLLLCS
                     INGTNREQDYLEMLRHNKVDGVVAITYSPIEHYLTSGIPFVSIDRTYSDIAIPCVSSD
                     NDAGGREAAKQLISKGCQHLAFVGGHNTTINETKRRRISFEKYVQEHKIPLSIFDLDE
                     TVTDYYGKLESFLEENSSIDGIFTINDFTALDVIEILKKNGKRIPHDVQIIGYDGIKM
                     AGDRDYLLSTIEQPLEEMAKEAVRILFDIIDGKTVNLQTILPVKFVEGKTTKNENKS"
     gene            3179..4096
                     /locus_tag="VXF95_000333"
     CDS             3179..4096
                     /locus_tag="VXF95_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001084977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1080936.1"
                     /translation="MNSKAKQVSLWERIKKQKLLLLMTVPGLVLTFIFKYIPMYGVLI
                     AFKDYNPLKGILGSDWIGFSEFTKFISSPNFGILLANTLKLSIYGLLLGFLPPIILAI
                     MLNQLLSEKVKKRIQLILYAPNFISVVVIVGMIFLFFSVGGPINNFLSMFGMKADFLT
                     NPDFFRPLYIFSGIWQGMGWASTLYTATLVNVDPALVEAARLDGANIFQRIWHIDIPA
                     LKPIMVIQFVLAAGGIMNVGYEKAFLMQTSLNLPTSEIISTYVYKVGLVSGDYSYSTA
                     VGLFNAVINVVLLVAVNQIVKRMNNGEGI"
     gene            4107..4997
                     /locus_tag="VXF95_000334"
     CDS             4107..4997
                     /locus_tag="VXF95_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1080937.1"
                     /translation="MKNSIMDTKFDRRILLLNKIIIVFIVLMTLLPLLYIVVASFMDP
                     KVLVSRGISFNPADWTVEGYQRVFSDQSILRGFINSLLYSFGFAALTVLLSVFTAYPL
                     SKKDLVGRRWINYFLIVTMFFGGGLVPTYLLVKELGMLNTPWAIIVPGAVNVWNIILA
                     RAYFQGLPEELVEAAVIDGANDLQIFFKIMLPLAKPIMFVLFLYAFVGQWNSYFDAMI
                     YIKDPNLEPLQLVLRKILIQSQPGQDMIGAQAAMNEMKRLAELIKYATIVISSLPLIV
                     MYPFFQKYFDKGIMAGSLKG"
     gene            5026..6642
                     /locus_tag="VXF95_000335"
     CDS             5026..6642
                     /locus_tag="VXF95_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1080938.1"
                     /translation="MKFKTFSKSAVLLTASLAVLAACGSKNTASSPDYKLEGVTFPLQ
                     EKKTLKFMTASSPLSPKDPNEKLILQRLEKETGVHIDWTNYQSDFAEKRNLDISSGDL
                     SDAIHNDGASDVDLMNWAKKGVIIPVEDLIDKYMPNLKKILDEKPEYKALMTAPDGHI
                     YSFPWIEELGDGKESIHSVNDMAWINKDWLKKLGLEMPKTTDDLIKVLEAFKNGDPNG
                     NGEADEIPFSFISGNGNEDFKFLFAAFGIGDNDDHLVVGNDGKVDFTADNDNYKEGVK
                     FIRQLQEKGLIDKEAFEHDWNSYIAKGHDQKFGVYFTWDKNNVTGSNESYDVLPVLAG
                     PSGQKHVARTNGMGFARDKMVITSVNKNLELTAKWIDAQYAPLQSVQNNWGTYGDDKQ
                     QNIFELDQASNSLKHLPLNGTAPAELRQKTEVGGPLAILDSYYGKVTTMPDDAKWRLD
                     LIKEYYVPYMSNDNNYPRVFMTQEDLDKIAHIEADMNDYIYRKRAEWIVNGNIDTEWD
                     DYKKELEKYGLSDYLAIKQKYYDQYQANKN"
     gene            6652..7971
                     /locus_tag="VXF95_000336"
     CDS             6652..7971
                     /locus_tag="VXF95_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1080939.1"
                     /translation="MGDKKYTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEETGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKDNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDIDYLEFGYDSNAQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(8179..8251)
                     /locus_tag="VXF95_000337"
     tRNA            complement(8179..8251)
                     /locus_tag="VXF95_000337"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8216..8218),aa:Lys,seq:ctt)
     gene            complement(8516..9787)
                     /locus_tag="VXF95_000338"
     CDS             complement(8516..9787)
                     /locus_tag="VXF95_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HEV1080940.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQKIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            10085..10300
                     /locus_tag="VXF95_000339"
     CDS             10085..10300
                     /locus_tag="VXF95_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080941.1"
                     /translation="MMELPSQEILIFTKQIRHWILSDQVISGKRKLFFWEDTPKEILD
                     LYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            10465..10644
                     /locus_tag="VXF95_000340"
     CDS             10465..10644
                     /locus_tag="VXF95_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080942.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSGPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            10781..10960
                     /locus_tag="VXF95_000341"
     CDS             10781..10960
                     /locus_tag="VXF95_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HEV1080943.1"
                     /translation="MPMTQKEMVKLLTAHGWIKTRGGKGSHIKMEKQGERPITILHGK
                     LNKYTERGIRKQAGL"
     gene            10997..11449
                     /locus_tag="VXF95_000342"
     CDS             10997..11449
                     /locus_tag="VXF95_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HEV1080944.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            11740..12210
                     /locus_tag="VXF95_000343"
     CDS             11740..12210
                     /locus_tag="VXF95_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HEV1080945.1"
                     /translation="MATYGFLDILEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVLSDDILFEEAVLFYNPAKSTVNEEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDVLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            12229..13332
                     /locus_tag="VXF95_000344"
     CDS             12229..13332
                     /locus_tag="VXF95_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HEV1080946.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLSGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERATTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNFWFPRL"
     gene            13298..13726
                     /locus_tag="VXF95_000345"
     CDS             13298..13726
                     /locus_tag="VXF95_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1080947.1"
                     /translation="MELEISGFPGCKIALFCEDKLLTILRDDKASIPWANMWELPGGG
                     REGDESPFECVAREVYEELGIHLTEDCLLWSKVYPSMLFADKQSVFLVGQLTQNQFDS
                     IVFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            13864..14814
                     /locus_tag="VXF95_000346"
     CDS             13864..14814
                     /locus_tag="VXF95_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000451122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HEV1080948.1"
                     /translation="METWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNVD
                     RFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTALA
                     EEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKMS
                     LFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNPG
                     MENIHVAAGDLLKGVEIEADVIVANILADILIHLIDDAYRLVKDEGYLIMSGIIKDKW
                     DMVRQSAESAGFFLETHMVQGEWNTCVFKKTKDISGVIGG"
     gene            14816..15559
                     /locus_tag="VXF95_000347"
     CDS             14816..15559
                     /locus_tag="VXF95_000347"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HEV1080949.1"
                     /translation="MQQYFVKGSAISPVTIEDKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLAQLDQ
                     FDFIIVAYEESAKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            15570..17366
                     /gene="pepF"
                     /locus_tag="VXF95_000348"
     CDS             15570..17366
                     /gene="pepF"
                     /locus_tag="VXF95_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1080950.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETD
                     ASVALTFFDDALVVADEEVLDRLGELPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            17613..18404
                     /locus_tag="VXF95_000349"
     CDS             17613..18404
                     /locus_tag="VXF95_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HEV1080951.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEGVSSDVGLDKEIDKVGLPTLERSFRALVYANLLYADANQ
                     QSVFYQGLQLEIRNVFSNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLTEVVCHPD
                     FPINRIHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLEQEQVASWIKTVD
                     FPIEEREDFSKFSNFRSCLVEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            18515..19183
                     /locus_tag="VXF95_000350"
     CDS             18515..19183
                     /locus_tag="VXF95_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HEV1080952.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGFDGLGHLGIAFAFSLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLAN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGPIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(19352..19441)
                     /locus_tag="VXF95_000351"
                     /pseudo
     CDS             complement(19352..19441)
                     /locus_tag="VXF95_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(19438..19764)
                     /gene="queF"
                     /locus_tag="VXF95_000352"
                     /pseudo
     CDS             complement(19438..19764)
                     /gene="queF"
                     /locus_tag="VXF95_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000082574.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="preQ(1) synthase"
     gene            complement(19759..19908)
                     /locus_tag="VXF95_000353"
                     /pseudo
     CDS             complement(19759..19908)
                     /locus_tag="VXF95_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730462.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase"
     gene            complement(20197..20511)
                     /gene="trxA"
                     /locus_tag="VXF95_000354"
     CDS             complement(20197..20511)
                     /gene="trxA"
                     /locus_tag="VXF95_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HEV1080953.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
     gene            complement(20528..20749)
                     /locus_tag="VXF95_000355"
     CDS             complement(20528..20749)
                     /locus_tag="VXF95_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1080954.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            complement(20848..21228)
                     /locus_tag="VXF95_000356"
     CDS             complement(20848..21228)
                     /locus_tag="VXF95_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1080955.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            complement(21371..22324)
                     /locus_tag="VXF95_000357"
     CDS             complement(21371..22324)
                     /locus_tag="VXF95_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1080956.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            complement(22392..23600)
                     /gene="sstT"
                     /locus_tag="VXF95_000358"
                     /pseudo
     CDS             complement(22392..23600)
                     /gene="sstT"
                     /locus_tag="VXF95_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            23739..24299
                     /locus_tag="VXF95_000359"
     CDS             23739..24299
                     /locus_tag="VXF95_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HEV1080957.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            24356..25264
                     /locus_tag="VXF95_000360"
     CDS             24356..25264
                     /locus_tag="VXF95_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1080958.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            25216..25806
                     /locus_tag="VXF95_000361"
     CDS             25216..25806
                     /locus_tag="VXF95_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HEV1080959.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYALTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            25809..26915
                     /gene="yqeH"
                     /locus_tag="VXF95_000362"
     CDS             25809..26915
                     /gene="yqeH"
                     /locus_tag="VXF95_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HEV1080960.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKLEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKNKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            27129..27440
                     /gene="yhbY"
                     /locus_tag="VXF95_000363"
     CDS             27129..27440
                     /gene="yhbY"
                     /locus_tag="VXF95_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HEV1080961.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            27492..28121
                     /locus_tag="VXF95_000364"
     CDS             27492..28121
                     /locus_tag="VXF95_000364"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HEV1080962.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEKNPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKV
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            28121..28714
                     /gene="yqeK"
                     /locus_tag="VXF95_000365"
     CDS             28121..28714
                     /gene="yqeK"
                     /locus_tag="VXF95_000365"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HEV1080963.1"
                     /translation="MSYQDYINCSREALLERMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKEN"
     gene            28715..29215
                     /locus_tag="VXF95_000366"
     CDS             28715..29215
                     /locus_tag="VXF95_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1080964.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLGKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEERFADVL
                     DYKHIF"
     gene            29228..29581
                     /gene="rsfS"
                     /locus_tag="VXF95_000367"
     CDS             29228..29581
                     /gene="rsfS"
                     /locus_tag="VXF95_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HEV1080965.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHVEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            29684..30430
                     /locus_tag="VXF95_000368"
     CDS             29684..30430
                     /locus_tag="VXF95_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1080966.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKEKKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFSMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYDILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            30440..31537
                     /locus_tag="VXF95_000369"
     CDS             30440..31537
                     /locus_tag="VXF95_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HEV1080967.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVRD
                     YQKIADLYTEKGAEMEKFVENLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            31775..32005
                     /locus_tag="VXF95_000370"
     CDS             31775..32005
                     /locus_tag="VXF95_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HEV1080968.1"
                     /translation="MEAVLYSTFRNHLKDYMKKVNDEFEPLTVVNKNPDEDIVVLSKS
                     EWDSIQETLRIAQNKELSDKVLRGMDKIRAGH"
     gene            32274..33887
                     /locus_tag="VXF95_000371"
     CDS             32274..33887
                     /locus_tag="VXF95_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HEV1080969.1"
                     /translation="MEFMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            34017..34643
                     /gene="gmk"
                     /locus_tag="VXF95_000372"
     CDS             34017..34643
                     /gene="gmk"
                     /locus_tag="VXF95_000372"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HEV1080970.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            34668..34982
                     /locus_tag="VXF95_000373"
     CDS             34668..34982
                     /locus_tag="VXF95_000373"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HEV1080971.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            35048..37444
                     /locus_tag="VXF95_000374"
     CDS             35048..37444
                     /locus_tag="VXF95_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HEV1080972.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKAMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARILRMDVDTTRKKGSHQALLDQFGRGKADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            37457..38392
                     /locus_tag="VXF95_000375"
     CDS             37457..38392
                     /locus_tag="VXF95_000375"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HEV1080973.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEDLMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            38385..39698
                     /gene="rsmB"
                     /locus_tag="VXF95_000376"
     CDS             38385..39698
                     /gene="rsmB"
                     /locus_tag="VXF95_000376"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HEV1080974.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLLAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSAYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNALLRRILREGWPDISSIKRKNKRDSIAYSLPVWLVAKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANNSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVADRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            39713..40453
                     /locus_tag="VXF95_000377"
     CDS             39713..40453
                     /locus_tag="VXF95_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HEV1080975.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIITSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDEE"
     gene            40450..42429
                     /gene="pknB"
                     /locus_tag="VXF95_000378"
     CDS             40450..42429
                     /gene="pknB"
                     /locus_tag="VXF95_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HEV1080976.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSVE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            42544..43302
                     /locus_tag="VXF95_000379"
     CDS             42544..43302
                     /locus_tag="VXF95_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1080977.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLMN"
     gene            43304..43753
                     /locus_tag="VXF95_000380"
     CDS             43304..43753
                     /locus_tag="VXF95_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HEV1080978.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            43815..44441
                     /locus_tag="VXF95_000381"
                     /pseudo
     CDS             43815..44441
                     /locus_tag="VXF95_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            44509..44757
                     /locus_tag="VXF95_000382"
     CDS             44509..44757
                     /locus_tag="VXF95_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080979.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
     gene            44888..46060
                     /locus_tag="VXF95_000383"
     CDS             44888..46060
                     /locus_tag="VXF95_000383"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HEV1080980.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTALSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            46060..47334
                     /locus_tag="VXF95_000384"
     CDS             46060..47334
                     /locus_tag="VXF95_000384"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HEV1080981.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRMAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(47369..48334)
                     /locus_tag="VXF95_000385"
     CDS             complement(47369..48334)
                     /locus_tag="VXF95_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1080982.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     GYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILVIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(48315..49769)
                     /locus_tag="VXF95_000386"
     CDS             complement(48315..49769)
                     /locus_tag="VXF95_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HEV1080983.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMKFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAINNDYTNWQAVGDLDFANDRT
                     AYMMECPNLVFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRVLAVSWLGLPDVSYPSDRFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNSQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            50146..52029
                     /locus_tag="VXF95_000387"
     CDS             50146..52029
                     /locus_tag="VXF95_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1080984.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     SQGNKVKAGDVLGTFDSNKIAAAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            52178..53065
                     /locus_tag="VXF95_000388"
     CDS             52178..53065
                     /locus_tag="VXF95_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1080985.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEMVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(53385..54002)
                     /locus_tag="VXF95_000389"
     CDS             complement(53385..54002)
                     /locus_tag="VXF95_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HEV1080986.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(54417..54605)
                     /locus_tag="VXF95_000390"
                     /pseudo
     CDS             complement(54417..54605)
                     /locus_tag="VXF95_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153868.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(55115..55195)
                     /locus_tag="VXF95_000391"
                     /pseudo
     CDS             complement(55115..55195)
                     /locus_tag="VXF95_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            55312..56205
                     /locus_tag="VXF95_000392"
     CDS             55312..56205
                     /locus_tag="VXF95_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1080987.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQETYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            56202..57401
                     /locus_tag="VXF95_000393"
     CDS             56202..57401
                     /locus_tag="VXF95_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1080988.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGILNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEV
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILVHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFFGVTALGAAGDNLLLKIGSYIPF
                     ISTFFMPFRTINDYAGGAEAWISLAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTF
                     KRALSYK"
     gene            complement(57754..58521)
                     /locus_tag="VXF95_000394"
     CDS             complement(57754..58521)
                     /locus_tag="VXF95_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080989.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLAISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAAYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVKELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(58538..59233)
                     /locus_tag="VXF95_000395"
     CDS             complement(58538..59233)
                     /locus_tag="VXF95_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1080990.1"
                     /translation="MSLLAFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            complement(59238..59603)
                     /locus_tag="VXF95_000396"
     CDS             complement(59238..59603)
                     /locus_tag="VXF95_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1080991.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            59743..60216
                     /gene="nrdR"
                     /locus_tag="VXF95_000397"
     CDS             59743..60216
                     /gene="nrdR"
                     /locus_tag="VXF95_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HEV1080992.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            60217..61386
                     /locus_tag="VXF95_000398"
     CDS             60217..61386
                     /locus_tag="VXF95_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HEV1080993.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLDHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSPKETTIIKEAKSKTALQFLAEIKQTRKGTTTQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEEAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            61387..62283
                     /gene="dnaI"
                     /locus_tag="VXF95_000399"
     CDS             61387..62283
                     /gene="dnaI"
                     /locus_tag="VXF95_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HEV1080994.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAIGDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTAWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKGKNGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            62280..62993
                     /locus_tag="VXF95_000400"
     CDS             62280..62993
                     /locus_tag="VXF95_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
                     /protein_id="HEV1080995.1"
                     /translation="MTETIKLMKAHTSVRRFKEQEIPQVDLNEILTAAQMASSWKNFQ
                     SYSVIVVRSQEKKDALYELVPQEAIRQSAVFLLFVGDLNRAEKGARLHTDTFQPQGVE
                     GLLISSVDAALAGQNALLAAESLGYGGVIIGLVRYKSEEVAELFNLPDYTYSVFGMAL
                     GVPNQHHDMKPRLPLENVVFEEEYQEQSTEAIQAYDRVQADYAGARATTSWSQRLAEQ
                     FGQAEPSSTRKNLEQKKLL"
     gene            63007..64317
                     /gene="der"
                     /locus_tag="VXF95_000401"
     CDS             63007..64317
                     /gene="der"
                     /locus_tag="VXF95_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HEV1080996.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPGMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            64408..64743
                     /locus_tag="VXF95_000402"
     CDS             64408..64743
                     /locus_tag="VXF95_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080997.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWIYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            64883..65233
                     /locus_tag="VXF95_000403"
     CDS             64883..65233
                     /locus_tag="VXF95_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1080998.1"
                     /translation="MEHLFKMIILLPCFYFFSWIDKDNRESKFFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGVHKGRCRN"
     gene            65482..65817
                     /locus_tag="VXF95_000404"
                     /pseudo
     CDS             65482..65817
                     /locus_tag="VXF95_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            65821..66471
                     /locus_tag="VXF95_000405"
     CDS             65821..66471
                     /locus_tag="VXF95_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1080999.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGVKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQYVKDIQS"
     gene            66482..66769
                     /locus_tag="VXF95_000406"
     CDS             66482..66769
                     /locus_tag="VXF95_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081000.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWLSFFFIPWDRAILGVRIDIFI
                     IQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFITFAILPIFGN"
     gene            66915..69428
                     /gene="secA"
                     /locus_tag="VXF95_000407"
     CDS             66915..69428
                     /gene="secA"
                     /locus_tag="VXF95_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HEV1081001.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDL
                     APEIQSMIKRTIERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            69509..70540
                     /locus_tag="VXF95_000408"
     CDS             69509..70540
                     /locus_tag="VXF95_000408"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1081002.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            70542..71573
                     /locus_tag="VXF95_000409"
     CDS             70542..71573
                     /locus_tag="VXF95_000409"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HEV1081003.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            71612..71980
                     /locus_tag="VXF95_000410"
     CDS             71612..71980
                     /locus_tag="VXF95_000410"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HEV1081004.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            71970..73073
                     /locus_tag="VXF95_000411"
     CDS             71970..73073
                     /locus_tag="VXF95_000411"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HEV1081005.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVRVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKPYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            73092..75107
                     /gene="recG"
                     /locus_tag="VXF95_000412"
     CDS             73092..75107
                     /gene="recG"
                     /locus_tag="VXF95_000412"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HEV1081006.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLNGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKDLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLDWSQEKVTAVKASLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQAYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
BASE COUNT        22470 a        14083 c        16992 g        21623 t
ORIGIN      
        1 tttgattctg tattcacgcc ctcaatagac ggtaaaataa gaaaattgtt tatatattgt
       61 ctccgtagtg ttattatacg aaataaaaga ttttaggaaa agtcgttata tcatgctata
      121 cctattcttt gtggtataat tgcaagaggt ttaatccgat aatttataaa gagagaaaga
      181 tattcatgag agatttatta tctaaaaaaa gtcataggca attagaatta ttagaattat
      241 tatttgaaca taaacgttgg tttcatcgtt ctgaactagc agagttatta aattgtacag
      301 aacgtgcagt caaagatgat ctatcccatg ttaaatctgc ttttcctgac ttgatttttc
      361 attcttctac taatggtata cgcattatta ataccgatga tagtgatatt gaaatggttt
      421 accatcattt ctttaaacat tcaactcatt tttcgatttt agaattcatc ttctttaatg
      481 aaggttgtca agctgagagt atttgtaaag aattttatat cagttcatct tcgctctatc
      541 gtattattag ccaaatcaat aaagtgatta aaaggcaatt tcaatttgaa gtcagtctga
      601 cccctgttca aatcattgga aatgagagag acattcgtta cttttttgca caatattttt
      661 cagaaaaata ttatttccta gaatggccat ttgaaaattt ttcatcagag ccactatctc
      721 aattgttaga attggtttat aaggaaacaa gctttccaat gaatttgtca acgcatagaa
      781 tgctaaagtt gctcctagtt acgaacctat atagaataaa gtttggtcat tttatggaag
      841 tagataaaga ttcttttaac gaccaaagtt tggatttttt aatgcaggca gaaggaatag
      901 aaggtgttgc tcagagtttt gaatcagaat acaatatctc tttagatgaa gaagttgttt
      961 gccaattatt tgtgtcttac tttcaaaaaa tgtttttcat agatgaaagt ctctttatga
     1021 aatgcgtaaa aaaggatagt tatgttgaaa aatcttacca tctattgagt gattttattg
     1081 atcagatttc agtcaagtat cagattgaaa tggagaataa ggataatctg atttggcatc
     1141 tgcataatac cgcacatctg tatcgtcaag agttgtttac tgagtttatt ttatttgatc
     1201 aaaaagggaa tacaatcagg aactttcaaa atatttttcc aaaatttgtt tcagatataa
     1261 aaaaagagct ttctcactat ttagagactc ttgaggtttg ttctagttca atgatggtaa
     1321 atcatctatc ttataccttc atcactcata ccaaacattt ggtgattaat ttgctacaaa
     1381 atcagcctaa actaaaggtt ttagttatga gtaattttga tcagtatcat gcaaaattcg
     1441 ttgcagagac actttcttat tactgtagca ataattttga actggaagtt tggactgaat
     1501 tagaattatc aaaggaatct ttagaagatt catcttatga tatcattatt tctaatttta
     1561 ttattcctcc tattgaaaat aagagactca tctattcaaa taatataaac acggtctcac
     1621 tcatatattt gttaaatgcc atgatgttta ttcgattaga tgagtaacca aaaataacaa
     1681 aaaaacgcta tttcgcgttt gaactgtacc tcaaaagtta gacagaaaaa gtctaatttt
     1741 tggggtgttt ttgttaagaa aataccttca atcatttaag caaaatgtac atctagattt
     1801 atagccatct aaaactcttg ctttttttgt agaagatacg aaaaaagcca tgaaaccaag
     1861 gcttttcctg ttttatgtag atgtttacac atgaaaattg aagtattttc aaaagctaat
     1921 tggagtgatt ttattcatga tgggataaat gatctggcca aaaatgattg agaaatagtt
     1981 gcttaaaaag catttgcatg atactatata ttgaaaggag gtgataatat ggtagaacaa
     2041 agaaaatcaa ttaccatgaa agatgttgct ttagaagcag gagttagtgt tggaactgtt
     2101 tcacgtgtaa ttaataaaga aaaaggcatt aaagaagtaa ctttgaaaaa agtggaacaa
     2161 gcgattaaaa ctttgaatta cattccagat tactacgcta gaggaatgaa aaaaaatcga
     2221 acagaaacga ttgcaatcat tgtaccaagt atctggcatc ccttcttttc agaatttgct
     2281 atgcatgtgg aaaatgaagt ctataagaga aataacaaat tactcttatg ttctatcaat
     2341 ggtacaaata gagagcaaga ctatctggag atgttgcgtc ataataaagt tgatggagtg
     2401 gttgccatta cctatagtcc aattgaacat tacttgacgt caggaattcc ctttgttagt
     2461 attgaccgca catactcaga tattgccatt ccttgtgttt catcagataa tgatgcaggt
     2521 ggaagagaag cagctaaaca attaattagt aaaggatgtc agcatttagc ctttgtgggc
     2581 ggacataata caaccattaa tgaaaccaaa cgtcgtagaa tttcatttga aaagtatgtc
     2641 caagagcata aaatacctct tagtattttt gatttggatg agacagttac tgactattat
     2701 ggaaagctag agagtttctt ggaagaaaat tcttctatag atggaatttt tacaatcaac
     2761 gattttacag ctttggatgt gattgaaata ctaaaaaaaa atggcaaacg tattcctcat
     2821 gatgttcaaa ttattggata cgatggaatt aaaatggctg gagatagaga ttatctactt
     2881 tcaactattg aacaaccatt ggaagaaatg gcaaaagaag cggttcgtat tttgtttgat
     2941 ataattgatg gaaagactgt taatttgcag acaatcctac cagtaaaatt tgttgaagga
     3001 aaaacaacaa aaaatgaaaa taagtcttga cagaaagcgc tatcaatgat agaatgaatt
     3061 cagataaaaa gatttatttt taaaacaaaa atgaaacgtt tcaaaaaaag aaataaagag
     3121 acagcgtcaa gcgctatctt ttctagaaaa aatgaaacgt ttcaaaaagg aggttgctat
     3181 gaatagcaaa gcgaagcaag tttctctttg ggaaagaatc aagaaacaaa aactcttgtt
     3241 attgatgact gtccccggtt tagttttaac ctttatcttt aaatacatcc ctatgtatgg
     3301 ggttttaatc gcatttaaag attacaatcc tttaaaagga attttaggga gtgattggat
     3361 tggtttttct gagtttacaa aattcatatc ctctcccaac tttggtatct tgttagccaa
     3421 cacattaaaa ttaagtatct atggtttatt gcttggcttt ttaccaccaa tcattcttgc
     3481 tattatgctc aatcaactct tgagtgaaaa agtcaaaaaa cgaattcagc tcattttata
     3541 cgcaccaaac tttatctcag tcgttgttat tgtcggtatg attttcctct tcttttcagt
     3601 gggaggacca atcaacaatt ttctttctat gtttggaatg aaggctgact tcttgacaaa
     3661 tccagacttc tttagacctt tatacatctt tagtggtatc tggcaaggaa tgggctgggc
     3721 ttcaacgctc tacacggcaa cattggtaaa tgtagatcca gccttagtag aagcagctcg
     3781 actggatgga gccaatatct tccaacgaat ctggcacatt gatattccag ctcttaagcc
     3841 tattatggtt atccaatttg ttttagctgc aggtggaatt atgaatgtcg gatatgaaaa
     3901 agcattcttg atgcagacat cgttaaattt gccaacttct gaaattatct cgacatatgt
     3961 ctataaagtt ggtcttgtat caggagacta ttcttactca acagcggttg gtttgtttaa
     4021 tgcagtgatt aacgtagtat tgcttgttgc agttaaccaa atcgttaaac gcatgaataa
     4081 tggtgaagga atttaaggag gaaagtatga aaaattcgat tatggataca aaatttgata
     4141 gacgtatctt actcttaaat aaaatcatta ttgtctttat cgttttgatg actttgcttc
     4201 ctttacttta tatcgtcgta gcatccttta tggatcctaa ggttctggtt agtagaggga
     4261 ttagctttaa tccagccgat tggactgtag aaggttacca gcgtgtattc agtgaccaat
     4321 ctattctaag aggttttatc aattctctac tatactcttt tggatttgca gctttaacag
     4381 tcttgctatc tgtgtttaca gcttatcctc tttctaagaa agacttggtt ggacgtcgtt
     4441 ggattaacta cttcttgatt gtaactatgt tctttggtgg tggtttagtc ccaacttact
     4501 tgctcgtaaa agaattggga atgctcaata ctccatgggc tatcattgtt ccaggtgctg
     4561 tcaatgtttg gaatattatt cttgctaggg cctatttcca aggattgcct gaagaattag
     4621 ttgaagctgc tgtcattgat ggtgcaaatg atttacagat tttctttaaa atcatgcttc
     4681 ctcttgcaaa accaattatg tttgttctct tcctctatgc ttttgtagga cagtggaact
     4741 catactttga tgcaatgatt tatatcaagg atccaaactt ggaaccattg caacttgtac
     4801 ttcgtaaaat tctcattcag agccaaccag gtcaagacat gattggagca caagcggcta
     4861 tgaatgaaat gaaacgttta gctgaattga ttaaatacgc aactattgtc atttccagct
     4921 tgccattgat tgttatgtat ccattcttcc aaaaatactt tgataaagga attatggctg
     4981 gttcacttaa aggataaaaa aagaaaaaat aaaaggagtt ttctcatgaa attcaaaaca
     5041 ttctcaaaat cagcagtttt gttgacagct agtttagcag tacttgcagc ctgtggctca
     5101 aaaaatacag cttcaagtcc agattataag ttggaaggtg taacattccc gcttcaagaa
     5161 aagaaaacat tgaagtttat gacagccagt tcaccgttat ctcctaaaga cccaaatgaa
     5221 aagttaattt tgcaacgttt ggagaaggaa actggcgttc atattgactg gaccaactac
     5281 caatccgact ttgcagaaaa acgtaacttg gatatttcta gtggtgattt atcagatgct
     5341 atccacaacg acggagcttc agatgtggac ttgatgaact gggctaaaaa aggtgttatt
     5401 attccagttg aagatttgat tgataaatac atgccaaatc ttaagaaaat tttggatgag
     5461 aaaccagagt acaaggcctt gatgacagca cctgatgggc acatttactc attcccatgg
     5521 attgaagagc ttggagatgg taaagagtct attcacagcg tcaacgatat ggcttggatt
     5581 aacaaagatt ggcttaagaa acttggtctt gaaatgccaa aaactactga tgatttgatt
     5641 aaagtcctag aagctttcaa aaacggggat ccaaatggaa atggagaggc tgatgaaatt
     5701 ccattttcat ttattagtgg taacggaaac gaagatttta aattcctatt tgctgcattt
     5761 ggtatagggg ataacgatga tcatttagta gtaggaaatg atggcaaagt tgacttcaca
     5821 gcagataacg ataactataa agaaggtgtc aaatttatcc gtcaattgca agaaaaaggc
     5881 ctgattgata aagaagcttt cgaacatgat tggaatagtt acattgctaa aggtcatgat
     5941 cagaaatttg gtgtttactt tacatgggat aagaataatg ttactggaag taacgaaagt
     6001 tatgatgttt taccagtact tgctggacca agtggtcaaa aacacgtagc tcgtacaaac
     6061 ggtatgggat ttgcacgtga caagatggtt attaccagtg taaacaaaaa cctagaattg
     6121 acagctaaat ggattgatgc acaatacgct ccactccaat ctgtgcaaaa taactgggga
     6181 acttacggag atgacaaaca acaaaacatc tttgaattgg atcaagcgtc aaatagtcta
     6241 aaacacttac cactaaacgg aactgcacca gcagaacttc gtcaaaagac tgaagtagga
     6301 ggaccactag ctatcctaga ttcatactat ggtaaagtaa caaccatgcc tgatgatgcc
     6361 aaatggcgtt tggatcttat caaagaatat tatgttcctt acatgagcaa tgacaataac
     6421 tatccaagag tttttatgac acaggaagat ttggacaaaa ttgcccatat cgaagcagat
     6481 atgaatgact atatctaccg taaacgtgct gaatggattg taaatggcaa tattgatact
     6541 gagtgggatg attacaagaa agaacttgaa aaatacggac tttctgatta cctcgctatt
     6601 aaacaaaaat actacgacca ataccaagca aacaaaaact agaggttgat tatgggagat
     6661 aagaaataca cagtagaaaa agccaatcgt tttatagcag aaaataaaca tctcgttaat
     6721 actcaatata agcctgaaga acatttttca gctgagattg gttggatcaa tgatccaaat
     6781 ggatttgtct attttcgtgg agaataccat ctcttttatc aattctatcc atatgatagt
     6841 gtttgggggc ctatgcactg gggacatgct aaaagtaagg acttggtgac ttgggagcac
     6901 ttgccagtgg cacttgctcc tgaccaagat tatgaccgaa atggttgttt ctcaggctct
     6961 gccattgtca aggatgatcg cctctggctc atgtacactg gacatatcga agaagaaacc
     7021 ggtgtccgcc aagtgcaaaa tatggcattt tcagatgacg ggattcactt tgaaaagatt
     7081 tcccaaaatc cagttgcaac tggatcagac ttgccagatg agttgattgc tgctgatttc
     7141 cgtgatccaa aactctttga aaaagatgga cgctattact ccgtagtagc tgccaaacac
     7201 aaggataatg tgggctgtat cgttctacta gggtccgata acctagtaga atggcagttc
     7261 gaatccatct ttttaaaagg ggtagaacac caaggcttta tgtgggaatg cccagattac
     7321 ttcgagttag atgggaaaga ttgccttatt atgtcaccca tgcgttatca gcgtgaggga
     7381 gactcatatc ataacatcaa ctcatcgctt ttgttcacgg gtaaggtaga ttggggagaa
     7441 aaatgtttta tcccagaatc agttcaagaa attgatcatg gccaagactt ctatgcgcct
     7501 caaacattgt tggacgatca aaatcgtcgt atcctgattg cttggatgca gacatggggg
     7561 cgtacccttc caacccatga ccaagaacac aaatgggcat gtgccatgac tttacctaga
     7621 attctaagat tggaagatgg caaactaaga caattccctg ttaaaaaagg ccaatatcaa
     7681 atccaaatag ataaagattg tcattaccac ttaggaaatg atatagatta tcttgaattt
     7741 ggttatgata gtaatgcgca gcaagtttac attgatcgta gccatcttat tcaaaaaatt
     7801 ctaggtgaag aagaacagga cactagtcga cggtatgtag atattgaagc taaagaattg
     7861 gaagttgttc tagataaaaa ttccatcgag atttttgtca atcaaggtga agcaagcttg
     7921 actgcaactt attacttaac ggtgccagct gagctatcac gaattgatta aaaattaagt
     7981 tatttctcct aaagaaaaag ttctctttct aaaatagtgg aaagaggact ttttgtgttt
     8041 tgggtatata agcttagttt atggtatttg taaaattggt gttggattat gatttaagct
     8101 agttttctaa agaatttgaa aaaaatttta tttaagcaaa aaaaccttgg ttccaaggct
     8161 tttcctgttg tatttagatg ccccctacag ggatcgaacc tgtgacccac ggattaagag
     8221 tccgctgctc tgccagctga gctaaggagg caaagaaaaa agctgtattg gtgccgaaac
     8281 ttcacggttt gtattgaacc cgcgcaatta agcaggtggg caactcgctc taactgaagc
     8341 tgtttccgtg tgagacggcc tacatgctgt tagaagactt ttgtttccct aataatacaa
     8401 aaaatagtcg gtcaacactt aagtgtgaag tcgtacacca cagcgtttct atatttatat
     8461 gataccactt tttcaaaaaa aatcaagagg aaagtgcagt tttttgaaaa ggatttcaga
     8521 tttttcgcaa atggtcgata gcttcctttc tttgagccaa agcccgttca tatttaccag
     8581 tatcttctgc ttggaaatag tgatgattac gaattttttc tggcagatag tcttgcttga
     8641 cccaatttcc aggatagttg tgtggataga gatagtcttg ggcattcccc agttccttgc
     8701 ttccactgta gtgcccatca cgcaggtgtc gcggaatagg caagtgccct gatgttttga
     8761 ggtcagcaag tgccttatcc atagctacat aggctgagtt ggattttgga gaaagggcca
     8821 aatcaatcac gacattggca atgagaatgc gggcttctgg gaacccaatc ttctgggcag
     8881 catccagagc agtcacggta tgaatctggg cctcaggatt ggctaagccg atatcttcat
     8941 aggcgataac agtcaagcga cgagcgagac taggcagatc cccagcctca atcaagcggg
     9001 cagtatagtg gagactggca tccacatctg agccacgaat agacttttgc agggcagata
     9061 gaacatcata gtgaccgtct ccatccttgt ccatagtgat gtagcttctc tgaagactat
     9121 tttccatgat gtctaaggtg atgtggcgaa tgccctcgtc attctcaggg gtagagagaa
     9181 cagctaagtc cagtgagtta aaggcagatc gaaggtctcc gtttgtagag gttgcgatga
     9241 aatccagcgc atcctcatct agttctattg gaaaatcaaa accacgttca gggttactta
     9301 gagctatctg cagggcctct ttgacgtctt ggttagacag aggttccaac tcgaaaattt
     9361 gaactcggct acgaatggca ggagtgacag agaagaaagg attttcagtc gttgctccaa
     9421 tcatgatgac cagtccactt tccaagagag gcaagaggaa gtcttgcttg gtcttatcta
     9481 gtcgatgaat ttcgtctagc aataggacga gaccaccaga aaatttagct tcttccgaga
     9541 tttcttgcag tcgcttttta ctatcaactg tcgcattgaa agttcgaaag gcatacttgg
     9601 tcgttccagc gatggcagag gcaatactgg ttttgccgat tccaggaggg ccatatagaa
     9661 tcatggagga caggcggttg gcttccacca tgcggcggat gatttttcca ggtccgacca
     9721 gatgctcctg accgatgacc tggtcgatgg ttttagggcg catgcgaagc gcgagattgt
     9781 ctggcatagc agtcctttct aacgtagatt tgagtagaat gactcatcta ctatatctta
     9841 ctatgtccat tctagcctat tagttgtgat atttcaatgg ttttgtaata atcagggagt
     9901 gagatagaat cttttttact atttaattta atgaggagag gtatcagcat gagagatttg
     9961 attttcctta aagctcaaaa taggatagtt gagcctaaag aagtggaagt gctgacttga
    10021 gaaataatat tgctaaatgt cattgtatga actataatga aaagagaggt gataagcaat
    10081 ggaaatgatg gaactaccaa gtcaggaaat tttgattttt acaaaacaaa ttcgtcattg
    10141 gattcttagt gatcaagtta tttcagggaa aagaaaactt ttcttctggg aagatactcc
    10201 aaaagagatt ttagatttgt acgaaaacat taaatctaaa cttgattttg cttaccaaga
    10261 agttcattct aataatgggt tgaaaaaata tgaaaaatag aataattgat gtttttgaag
    10321 tagtaaatcg cctccttgta ataactgttg aaaatcctga tttcgaagac ttgagagtta
    10381 atcatactca atgaaaatca aagagcaaac taggaaacta gccgcaggct gtacttgagt
    10441 acggtaaggc gacgttgacg tggtttgaat ttgattttcg aagagtatca gtttgtaaaa
    10501 attggagata aaaaatatag agtacgcagt ggtcctatga ttcattcaac tccgcctcaa
    10561 tctgtcttag atcgagatac ttttacaatt gactatacag atgatgaatt gctcgataaa
    10621 gaagcagttt ttactactca ttagaaaaat aggtatgaat aaattggctt cccttagaac
    10681 cacatctagg ggcttttatg tataatagaa taataagtat cactccttta caatacgtgt
    10741 aacacgtgtt ataatggtgt tgtcaggagg taaaagcgct atgcctatga cacaaaaaga
    10801 gatggttaaa ctccttacgg cccatggttg gataaagact agaggcggta aaggctccca
    10861 tattaaaatg gaaaagcaag gggaaagacc tatcacaatc cttcatggta agctgaataa
    10921 gtacactgaa agagggataa gaaagcaagc tgggttgtaa aattcagccc ctgctttttg
    10981 atatagaggt agtgaaatgt tagttacgta tccagcttta ttttattatg acgacacaga
    11041 cggaacagaa gcgacttatt ttgtccattt cccagatttt gaatactcag ctacacaagg
    11101 agaggggatt tctgaggctt tggctatggg gtcggagtgg ctagggataa ctgttgcaga
    11161 tttgatagag agtgatggag agttacctca gccatcagat attaatagct tgtctttaat
    11221 tgataatgat ccttttaaag atgatgaaga tttcgtgtca acctatgacc ttgataaatc
    11281 ttttatttct atggtatctg ttgatgtatc agaataccta ggaagtcagg aacccattaa
    11341 aaagactttg actataccaa aatgggcaga taagttggga cgagaaatgg gacttaactt
    11401 ttctcagact ttgacagacg ctattgcaga taagaaagtt caagcctaag attaagcgtg
    11461 gtatcgtggt aatagtcaat aaaaaagcac gtccacttgt gctagttact cgcctattga
    11521 ttttatagat ttattagccc tttcgcgggc tttttatatt gatttttatg agaaatgaag
    11581 aaatcagact tttaagaaaa tcattgatac caagggttta aatgaggtaa tatggtataa
    11641 ttaggacata aaataatttt gtggtaagat ggtagtatct attttagcat atttccgagc
    11701 aatcggggcg attaaagagt cgcatagaaa gaggacaaaa tggcaacata cggattttta
    11761 gatattttag aggaagagtt ggacaagaac tttccctttg actttgagat tagttgggac
    11821 aagcgtaacc atgcggtaga agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg
    11881 gagatggtgg atgaagacgg agaggtttta tcagatgaca ttctttttga ggaagcggtc
    11941 cttttctaca atcctgccaa gtcaacagtc aatgaggaag actatttgac tgttattcct
    12001 tacctgccta aaaaaggatt ttcccgtgaa tttttagctt attttgcgct tttccttaaa
    12061 gatactgctg aggttgggct agatgtcctc atggactttt tggaagaccc agaagcagag
    12121 gaatttgtca tggaatggaa ccaagaagtc tttgaagaag gaaaagttgg cttggaagag
    12181 ggagaatttt atccttatcc aagatactag gagttggttg gaggtgttat gaagaaaatt
    12241 gggacttatt tggtttatgt gctagctgtt gtctttatta tgctagcttt tgcttgtgga
    12301 acaatcgcat ttgcagagtt ggggtattcc gcagttttag cctttacttt tggttatgcc
    12361 ttcgctcttc taagcatgta tttaattttt attcttcatg agctgggtca tgctttttgt
    12421 ggctacttga caggctatcg gctggtggct tttggattag gacattttat tttgaccaaa
    12481 aagtcaggca ggtttcatct tagtagaaca gccattctga aaaatgttgg tgctcaatac
    12541 attggtttaa aagaggatga aagcgatcaa agaatcatcc tgatgctttc aggaggcttg
    12601 atggttcatc tcggcttgat attattggcg atagtgtttg gatttttgac aagaagctgg
    12661 tattttgcag ggacttggat ttttcttaat ttatctttct tcctaaataa cattttgcca
    12721 gtcgacatca ccgatggagc aaaaatttgg gaattactac aacaccctga aaataccaaa
    12781 tacgcctacc tggtattgag acattctgct caaactttgc tggctcctca agaatatgat
    12841 ttgaaagact ttgttcaagc agttcctgag gatgcacgag ggagttttgc ggatggtgta
    12901 ttaggtatgc aaggtgaagt ttccattttg gaagggaagg aagaagtagc taaacagcag
    12961 tttcaagcat tacttgagag ggcaactact ccgatgatgc agacagttgc ccaactatcc
    13021 ctgcttcata tcgccttgtt ggaaggagat tttgagcaag cggagcaata tgctagtatt
    13081 cgacaggtca aatcgtttct gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg
    13141 tatcaattaa aggtgaagaa agatgtagat cgaactcgta aggctctcaa gattgctaga
    13201 cagaaaatgg atagtagtcg aatgttgagg gacgagaaac gctattatga aaacttgtta
    13261 gccgagctgg aaaaggaaat gttagaagga actgaagatg gaactagaaa tttctggttt
    13321 cccaggctgt aagattgctt tgttttgtga ggataagctc ttgactatct tacgtgatga
    13381 taaggcaagt attccctggg ccaatatgtg ggaactgcca ggtggtggac gtgaaggtga
    13441 tgaaagtcct tttgagtgtg tagcgcgtga agtttatgaa gaactgggca ttcatctgac
    13501 tgaagattgt ctgctttgga gtaaggttta cccaagtatg ctttttgcag acaaacagtc
    13561 cgtttttcta gttggtcagt tgacacagaa ccagtttgac agtatcgtat ttggagatga
    13621 aggacagggc tatcagctga tgaatgttga ggaatttctt agttccagtc aagttgtccc
    13681 tcagttgcaa gagagattaa aagattattt aaaagtaagt gattagaaag gatggttcag
    13741 ttaaatttct aaactgaacc cgccctaaac actgtgccaa aaagataaac ttctcttaga
    13801 cacaagcgtc ttcagagaat ttcctatttt ggttttgtgt tttacgggct tggtatctta
    13861 ataatggaaa catggcaaga gttaaaagtt acagtgaagc gtgagggaga ggagttggtt
    13921 tccaatctct tgattgagct gggagcgcaa ggagtcgcaa tcgaagacag tatggactat
    13981 gtgggaaatg ttgaccgctt tggcgagatt ttcccagagg tggagcagca agaagaaatc
    14041 gttgtgacag cctactaccc tgacacggtg gatgtgacag tggttgaggc ggacttgcag
    14101 gctcgcatat cagaattgac ggattttatg gatttgggag agttaaaaat aggtacgact
    14161 gccttggctg aggaagactg ggcagacaac tggaagaaat actatgagcc agctcgtatc
    14221 actcatgatt tgaccatcgt tccctcttgg acagactatg aggcgactgc gggagaaaaa
    14281 attatcaagc tggatcctgg catggctttt ggtactggaa cccacccaac taccaagatg
    14341 agcctttttg ccttggaaca ggttcttcgt ggtggcgaaa cggtgctaga tgtggggact
    14401 ggttcagggg ttctctctat tgccagctcg cttctggggg ctaaagaaat tttcgcctat
    14461 gacctggatg atgtggcggt tcgtgtggct caggaaaata ttgagctcaa ccctggcatg
    14521 gaaaatatcc atgtagcggc tggagatttg cttaagggtg tggaaattga ggcagatgtg
    14581 attgtggcta atatcttggc ggatatcctc attcatctaa tagacgatgc ctatcgtttg
    14641 gttaaggacg aaggctacct gatcatgagt ggcattatca aggacaagtg ggacatggtg
    14701 cgccagtcgg ctgagtcagc tggatttttc ctcgaaactc acatggttca aggggaatgg
    14761 aatacctgtg tctttaagaa aaccaaggat atctctggtg tgattggagg ctagcatgca
    14821 gcagtatttt gtaaaaggca gtgctatctc tcctgtcact atcgaggaca aggaaaccag
    14881 taagcatatg tttcaggtta tgcgcttgaa agaagaggat gaggttacct tagtctttga
    14941 tgatggcatc aagcgcttgg cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt
    15001 ccaagaatta aatgacaatg tggaactacc agtccaagtg accatcgcat ctggatttcc
    15061 caagggagac aagctggagt tcatcgctca aaaagtaacc gaactgggtg ctagccaaat
    15121 ctgggccttt cctgcagact ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa
    15181 agttgaaaaa ctagaaaaaa ttgcccttgg agcagccgag caaagcaagc gtaatattgt
    15241 accaagtatt aaacttttcg agaaaaaagc agattttcta gctcagctgg accagtttga
    15301 ctttatcata gtagcctatg aagaatcagc taaagaagga gaagccgctg cgcttctgca
    15361 agcagtcact ggtcttgaaa caggagccaa actgctcttt atctttggtc cagaaggcgg
    15421 tctctcacct gcagaaatcg aaagttttga agctaaggga gccgttttgg taggcctagg
    15481 tcctcgtatt ttgcgagcag aaacagcacc gctttacgcc ttatcagccc ttagtgtttt
    15541 agtagaatta gagaaataag aggaagaaaa tggaacaaaa acaccgttca gaatttccag
    15601 agaaggaact ctgggactta acagccctat accaagaccg tgaggatttc ttgcgtgcaa
    15661 tcgagaaagc tcgtgaagac atcaaccagt ttagccgtga ttacaagggc aatcttcaca
    15721 cttttgagga tttcgagaag gcctttgcgg aattagaaca gatctacatt cagatgagcc
    15781 atattggcaa ctatgctttt atgcctcaga cgacggacta tagcaatgac gaatttgcca
    15841 atattgccca agctgggatg gaatttgaaa cagatgccag cgtagccttg accttctttg
    15901 acgatgcctt ggtggtagca gacgaggaag tcttggaccg tttgggtgaa ttgcctcact
    15961 tgacggcagc tattcgtcag gccaaaatca aaaaagccca ctatctaggg gctgatgtgg
    16021 agaaggcctt gaccaatctc ggtgaagttt tctatagtcc gcaggacatt tatactaaga
    16081 tgcgagctgg ggattttgaa atggctgact ttgaagccca tggcaagacc tataaaaaca
    16141 gctttgtcac ctatgagaat ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat
    16201 ccttccgttc cttctcagag ggacttcgta agcaccaaaa tacggctgca gcagcctatc
    16261 tggctcaggt caagtctgaa aaactcttgg ctgatatgaa gggatacgac tctgtatttg
    16321 attatcttct agctgaacaa gaagtggacc gtgtcatgtt tgaccgccag attgacctca
    16381 tcatgaagga ctttgcacca gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg
    16441 gtcttgaaaa gatgaccttt gcagactgga aattggactt ggacagcgcc ctgaatcctg
    16501 aagtgactat tgacgatgcc tatgatttgg tcatgaagtc ggtagaacct ttggggcaag
    16561 aatattgtca ggaagttgct cgttaccaag aagagcgctg ggtggacttt gctgctaaca
    16621 gtggcaagga ttccggtggt tatgcggcgg acccatatcg cgtacaccct tatgtactca
    16681 tgagctggac aggccgtttg agcgatgtct ataccttgat tcatgaaatc gggcattctg
    16741 gtcaattcat cttttcagac aatcaccaaa gctatttcaa cgcccacatg tcgacctatt
    16801 atgttgaagc accgtcaacc ttcaatgaat tgctactcag tgattactta gagaaccagt
    16861 ctaatgaccc acgtcaaaaa cgcttcgctc tggctcatcg cttgacagac acctacttcc
    16921 ataatttcat cacccacctc ttggaagccg ccttccagcg taaggtgtat acattgattg
    16981 aagaagggga gacctttgga gcaagcaagc tcaacagcat tatgaaggaa gttttgacag
    17041 atttttgggg cgatgccatt gaaatcgacg acgatgcagc tttgacttgg atgcgccaag
    17101 ctcactacta tatgggcttg tatagttaca cttactctgc tggtcttgtc atctcgacag
    17161 ctggttacct tcatcttaaa aactcagaaa ctggagctga agactggctc aatctcctca
    17221 aatcaggtgg tagcaagaca ccacttgagt cagccatgat tatcggtgct gatatttcaa
    17281 cagacaaacc actccgtgat accatccaat tcttgtctga cacagttgac cagattatcg
    17341 cctacagtgc tgagttgggg gagtaagggg aatagaaaaa ttttttagaa tgatgtttat
    17401 gggcttgtta agcgtcattc tatttgtctt agttgtagct attttcaaaa atgtcgttga
    17461 aggtcgtgat gttaaatttg aacttactgt agaactggta ttgatagtta tttacgtcat
    17521 tttatatcag attgtattta attgagaatt caatattgag tcatttaaga ctgccttttt
    17581 gaacagttgc tagaaatgta gaggtattga ccatgtatca agatttacta agaaaaatag
    17641 cagaagaaaa accaaattat aaccaggagg aaatccagtg gttgcttgat catttgggag
    17701 atccttctcc agaaattcgc gatgaccttg tttttacaag ctttgctaga gggattcagg
    17761 aagagctatt tacacaggag caatttcatt tcattgctga aggggtttca tctgatgtag
    17821 gactagataa agagattgat aaggtaggtc tgccaacact tgaacgttct tttagggcac
    17881 ttgtttatgc aaatctcttg tatgcagatg ccaaccagca atcggttttt tatcagggat
    17941 tacaattaga aattcgtaat gtcttttcaa atcaaggctt gcactatctt tcaaaagaaa
    18001 aggatacaac aggtttctca agtcagtatg gttgggttca tgcttttgca catggagccg
    18061 atttactgac agaggtggtc tgtcatccag actttcctat aaacagaatt catgaagtat
    18121 ttgacatact tggccaacta tttaaaagaa tgtcgattcg ctttacagat gatgaggatt
    18181 ggcgtttagc aagagtgatc tatgaaccta ttttacaagg gaagttggag caagaacaag
    18241 tagcttcttg gataaaaact gttgattttc cgatagaaga aagggaggat ttttccaaat
    18301 tttccaactt tagatcctgt ctggtggaag tctatgtcca acttgaccag agaaatagtt
    18361 tacaagatga gttgaaagaa gctatccagt cttttcaata ctagagatta gctaatagtt
    18421 ctatgatttt caaaaaattt ccaatcaatt ttcttgaaac cctttcctac ttttgataga
    18481 ctagtatcta gtttttgaaa aaaggagaaa gaaaatgaaa aaatttgttg ctgagttaat
    18541 cggtacgttc atgcttgtgt tcgttgggac aggagctgtt gtttttggaa atggttttga
    18601 tggccttggt caccttggaa tcgcctttgc ctttagtttg gcaatcgtgg tggcagccta
    18661 ctcaatcgga actgtttcag gtgctcactt gaacccggct gtttcgattg ctatgtttgt
    18721 aaacaaacgt ttgtcatctt cagaacttgt aaactacatc cttggtcagg ttgttggagc
    18781 tttcatcgct tctggcgctg tcttcttcct cttggctaac tcaggtatgt caactgctag
    18841 tcttggtgaa aatgccttgg caaacggtgt cactgtcttt ggtggtttct tgtttgaagt
    18901 catcgcaact ttcttgtttg tattggttat catgactgtg acttcagaaa gcaagggcaa
    18961 tggcccgatt gctggtttgg taatcggttt gtcattgatg gcgatgattc ttgtcggatt
    19021 gaagattact ggactttcag taaacccagc tcgtagcttg gcaccagctg tcttggtagg
    19081 cggcgcagcc cttcaacaag tttggatttt catccttgca ccaatcgctg gtggagttct
    19141 tgcagccctt gttgcaaaaa atttccttgg aacagaagaa taattgaaac tcaaaaagcc
    19201 ttgctcctca tcttgaggaa cagggctttt tcgtatgata ctcttcgaaa atctcttcaa
    19261 accacgtcag cttcaccttg tcgtaggtat ggttactgac ttcgtcagtt ctatctgcaa
    19321 cctcaaaaca gtgttttaag ctgacttcgt cagttctatc tgcaacctca aaacagtgtt
    19381 ttgagtaacc tgcggctaac ttcctagttt gctctttgat tttcattgag tatgacttta
    19441 gcggttgtca attttctctg gataaaggtc gtgttggaag aggcgttgtt ctgccaagcc
    19501 ctcatactta gttccttgct taccgtagtt gtagtagggg ttgattgaaa tgccaccgcg
    19561 cggagtgaat ttcccccaga cttctaaata gcgagggtct agcaagttga ccaagtcttt
    19621 cccgatggtg ttgatacagt tttcgtggaa atctccgtgg tttcggtagc taaatagata
    19681 tagtttgagg gattttgact cgacacagag tttgtcagga atgtaggaaa tatgaatcgt
    19741 cgcaaagtct ggctgagcag tgatttgtcc cagcagagac atatcgagga tatggtgacg
    19801 aatgccctgt tccttagcga tttctctatt aatttgaatt tcgaggtgat gacgttggcc
    19861 gtaggcaaag gtgacagctt cgactgtttc atagtactcc ttccaaaatg ggaaatgttc
    19921 agagcatgca aaaagctccc attagggagc taaaaaatac caaatcgagt ttttttagcg
    19981 atggcatatc ccaaacatcg taatattcta cttatatagt aaaatgaaat aagaacagga
    20041 caaatcgatc aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta
    20101 ttctagtttc aatctgctat agtctagcat attttttgaa aaatggcaaa gggcaagaaa
    20161 aaagagacca aagaaagtac ttggtctctc gtttgattag ctcaattcag caatgatggc
    20221 cttgatttgt tctgctgtgt gaacacctgc aacttgtttg acaacttggc cgtctttttt
    20281 gaagagaaga gttggaatag acatgattcc aaaagcacga gctgtgtttg gattttcatc
    20341 aacgtccatt ttaacgattt tcaagacatc ttctgaaagt tcttcagaca atttgtccaa
    20401 gattggacct tgcatacgac atggaccaca ccaagttgcc cagaagtcta ctaagaccaa
    20461 accgtctttt gtttcttgtt cgaatgttgc atctgtaatt gcttttgcca ttgtatttct
    20521 ccttttttta gttatattgg cttaaatctt gtttcatgag atagaagaag atatctccat
    20581 aagtcccatg gtagtccaaa ttatgaccct tgtaagttaa tttttggaca gggtagtagt
    20641 ctgcgacgcc gataaggcaa gcttgttgcg aacgttcaaa gtcttcataa gactcgaaag
    20701 tcacagttct ttcgttcttg ctggcatcta tataggtaat ttcaatcatg tttaaaactc
    20761 ctttgtttaa tgctaacttt attttactcc ttataaaaga gaatgtcaag aaaaatgatt
    20821 gcgcacgcaa ctttttttaa aatcatctta aatcaagaaa tccaaacctg cttccaagct
    20881 ttcttcgaca gtcttttgta gcgaggccag tgtcttttgc ccatcatttg tcaggcagat
    20941 aaaactagag cgtctatctt gatggcaaca catgcgactg agtagaccgc aatttttagc
    21001 ttccaagcga gccaccatcc tagaaactgc gctcgggctc agatgaagct tatctggcag
    21061 gtcaatctgg cgtagagatt tttcttcagc caagtccaga tagtagagca ggtagaactc
    21121 tttcaaggtc agactttgct cgctctgttg ggcaatggtc tcttccaaga gactttcaat
    21181 ttctttctga cgccgattga agtcaaacca tttttccaaa taggtcatag tgtctccttt
    21241 ctttttagag tcataaatag aagaaagtcc attaacgggc agtctctgcg tcacaagatg
    21301 attgcgcatg caataattat actacttttc aagaatgctg gcaagctctg ttttttagtg
    21361 gttttatttt ttactgtcta tatttttggt aaaaatcaac ttttacttgg atgaaggttt
    21421 tggcttcacg taggagttga agaagggtgg cgcgggtttc aaactcttct cttgtcttgg
    21481 gcagactgcg gttccggaag acttccagat aacgttcaat ttcatctagc aaatcagaag
    21541 caggattggt ctggctcagt tgacctgcaa tttttgaaaa gagttgcgct aagatcaggc
    21601 tttcactggc ggcaaggtga caagtgttaa tctgttgggc catgtttctc aggatacgac
    21661 tttgtcgttg tctcatctca aagtagtgga tatggtagtc ggtctggtga aagaggtggt
    21721 cagagtgatc caaatagacc agtctgaggg cttctttcaa aagcgtgtct aattctgcta
    21781 ccagctgtgc tcggttgcgt ccgtctcctc tggataaata gtatttgaag cgctggagga
    21841 tatcttttaa cttttcttcc accagcgtgt ggtagtgctg gatttcctct tctcgtgaag
    21901 gcatatagag attaacaagc aaggcaaatc ctgtaccaat agcaaagaga aggaattcgt
    21961 tgactaggag gtctggagag gttgactctt gaaccaagag atggctaacc aaaaccgtgc
    22021 ttggtgtgat gccaatttcc cagcccatct tgtaggctaa aggaacgtag aaggccagat
    22081 agaggccgag actccagata tgaaatccgc tcaagtgaaa agctagaaca ccgatagcca
    22141 gagctagaag catagaaaaa agacgattgc gagccagttt taaagtactt ctacgcgtat
    22201 cagataggct caagagagcg ataattccag ccgaaactgc tgacgaaaga ttgagaaaat
    22261 aagcaagcag gcaggcaaga caggtagcta agatgagctt ggtcgtacgt tggctaatag
    22321 acataagaat ttcctaataa gttagaataa aagcgtaaaa gacaagacat gagcaggctt
    22381 gccttgatga gttatttttt acgggttgct gcgtattcgg caacggcggt aaagaggaca
    22441 tctgtagaag agttaagggc tgtttcacat gagtcttgga tgacaccaat cacaaaacca
    22501 accccaacaa cttgtatggc aatatcgtta gaaataccga aaaggctaca agcaactggg
    22561 ataagaagga gggaacctcc ggcaatacct gaagcaccac aggctgagat agctgctacc
    22621 acactgagga caaaggctgt ggcaaagtca acaggaattc caagagtgtt aactgcagca
    22681 agggtcaaaa ggttaatggt aatcgctact ccagccatat tgatagtaga accgagtggg
    22741 atagaaacag aataggtatc tgggttgagt ccaaggtcat ggcagagttt catgttgaca
    22801 ggaatgttag tcgcagaact acgagtgaaa aaggctgtca caccgctgac acggaggcag
    22861 ttccaaacta gagggtaagg attgcgtctc ataaagaaga aggcaatcaa agggttgacc
    22921 acaggggcaa caaaaagcat agtcgttact aatagaacca ataaaatacc gtagttggca
    22981 aggcttccga ctcccttgtc agaaatggtt ttaaaaacaa gaccaaggat tccaaatgga
    23041 gccagattga tgatccattc gacaatttta gaagtcacgt cagcgatagt ttttagcaat
    23101 tctttactat ttttactggc ttctctcata gcgattccaa aaatgactgc ccaagataag
    23161 attctaatat agttagcagt aagcagggcg ttgactgggt tgtcaaccag tttgagcaag
    23221 aggttgctga ggacctgccc aatcccatct ggtggtgcaa tttcagtatt ggcactattt
    23281 agggtaattt caatagggac gatgaaactt gctagtacag ctacaagagc agcggcgaaa
    23341 gtccctatca taggatatac aagaaaacaa cagttttcat attgctatct tgtccctttt
    23401 gatgttggaa agggcattgg caacgagggc aaagactagg ataggagcaa cagcttttag
    23461 acctccaacg aataaatccc cgagtagccc aatccctgag agattaggaa gggtcagtcc
    23521 taggattccc cacaaagcat accaatcaag atacgcttga caaggcttgc cttattccaa
    23581 gcatgaatga ttcttttcat aataatctcc tttttgtgta gtgattatga ttatagtata
    23641 aatgatagac aaaatcaaga attttctgtc tgttttttga atatttatgg agaatgagac
    23701 tgatgaaaat atggtataat gaaataaagg agttttatat gcaaaaattt attcaggctt
    23761 atattgaaaa gctagatgtg acaaccatta tcgagaatat tctaaccaag gtcatttctc
    23821 ttttactgct tttgattgta ttttatattg ctaaaaaaat gcttcatacc atggtgcaga
    23881 gaattgtcaa accttctcta aaaatgtctc gtcatgatgt cggacgccaa aaaaccatct
    23941 cacgtttact agaaaatgtg tttaattata cgctatattt ctttttactc tactgcattt
    24001 tgtcgatttt aggtttgcca gtttctagtt tgctggctgg agctggtatt gctggggtag
    24061 cgattggtat gggagcccaa ggctttctgt ctgatgtcat caatggcttt ttcatcctct
    24121 ttgaacgtca actggatgtg ggagatgagg tcgttctgac aaatggaccg attactgtat
    24181 cgggtaaggt tgtcagtgtg ggaattcgta cgacacagct tcgtagcgag gagcaagccc
    24241 ttcactttgt ccctaaccga aatatcacag ttgttagcaa tttctcacgc acagactaga
    24301 cctgttattt taagtaattt gtggtacaat agagggagtt taataaggag aaaagatggt
    24361 tttagaaaag cagttgggca atggttgtac ctggatagac ctagacctag gaaagttgaa
    24421 taaactagaa gacctttctg aaatttacgg tttggacaag gaaaccattg aatacgcact
    24481 ggatagaaac gagcgcgccc acatggatta ccaccgtgaa agtgggacgg ttacctttat
    24541 ctataatgtc ctagacgtaa aaaaggacaa ggcctactat gagacttttc ccatgacctt
    24601 tattgtcgag catcgtcgcc tgattaccat tagtaatacc aagaacgcct atgtcattga
    24661 acagatgact cgttatctgg agagccatga cacgctttcg atttataagt ttctctttgc
    24721 cagtctggaa attatcagca atgcctacta tcctgtcatt gagcagatgg acaagagtag
    24781 ggatgaggtc aatgacctct tgcgccagcg aactaccaag aaaaacctct ttgccctgtc
    24841 tgatttggag actggtatgg tttatctgac ggcagctgcc aaacaaaatc ggattttgtt
    24901 agagcatatt caaggtcatg ccttgtatcg tagttttgat gagattgaga gagaacagtt
    24961 tgatgatgcc atgattgagg ctcatcagct ggtatccatg acagacctaa tctctcagat
    25021 tttacagcag ctttcagcct cttacaacaa tattctaaac aataatctga atgacaattt
    25081 gacaaccttg actatcattt cagtcttgct agctgttttg gcagtcgtga caggcttttt
    25141 cggaatgaat gttcccttac ctttaacaga tgagccccat gcttggctct atatcagttt
    25201 ggctagtgca ggtttgtgga ttgttttatc cttgttacta aggaaaattg cgaaaaaaag
    25261 ttaagaaaag gagccagaat ggcgattgaa aattatatac cagattttgc tgtggaagca
    25321 gtctatgctc tgacagtccc aagcctgcag gcgcagggaa tcaaggctgt tttggtcgat
    25381 ttggataata ccctcattgc ttggaacaac cctgatggaa cgccagagat gaagcaatgg
    25441 ctacatgacc ttcgggacgc gggtattggc attatcgtag tgtcaaataa caccaaaaaa
    25501 cgcgttcaac gagcagttga gaaatttggg attgattacg tttactgggc cttgaagccc
    25561 ttcacatttg gtattgaccg tgctatgaag gaattccact atgacaaaaa ggaagtggtc
    25621 atggttggcg accagctcat gacagatata cgagcagccc accgtgcagg gattcggtca
    25681 attttagtca aacccttggt ccaacatgac tcaatcaaaa cgcagattaa ccgaactcgt
    25741 gagcgtcgtg ttatgagaaa aatcactgaa aagtacggac cgattacata taaaaaagga
    25801 atttaactat ggaagaaatt ctctgtattg gttgtggagc aaccattcag acgacagata
    25861 aagctggtct tggttttacc ccccagtcgg cacttgaaaa aggtttggag actggcgaag
    25921 tctattgcca acgctgtttc cgtctccgcc actacaatga aatcacagat gtccagttga
    25981 cgaacgatga tttcctcaag ctcttgcacg aggtgggaga cagtgatgcc ttagtggtca
    26041 atgtcattga tatctttgat tttaatggat ctgtcatccc aggtttacca cgtttcgtct
    26101 cgggcaatga tgtcctcttg gtaggaaata aaaaagatat ccttcctaag tcagttaagt
    26161 ctggtaagat tagccagtgg ctcatgaaac gtgcccatga agaaggtctt cgtccagtcg
    26221 atgtggtcct aacttcagca caaaataaac atgccattaa ggaagtcatt gacaagattg
    26281 aacactaccg taagggccgc gatgtctatg tggtcggtgt gaccaacgtt ggaaaatcaa
    26341 ctctaatcaa tgctattatc caagaaatca cgggtgatca gaatgtcatc actacttcac
    26401 gcttcccagg tacaaccttg gacaaaatag agattccgct tgacgacgga tcttatattt
    26461 acgatacgcc gggaattatc caccgccacc agatggctca ctacttgacg gccaaaaacc
    26521 tcaagtatgt cagtcctaaa aaggaaatca agcctaagac ctatcagctt aatcctgagc
    26581 aaaccctatt tttaggtggt ttgggacgct ttgactttat agcaggagaa aagcaaggat
    26641 ttactgcttt ctttgataat gaactcaaac ttcatcgtag caagcttgaa ggagctagtg
    26701 ctttctacga taagcacctg ggaactcttc tgacaccacc aaatagcaag gaaaaagaag
    26761 atttcccaag gctagtccag catgtcttta ccattaaaaa taagacagac ctagtcatct
    26821 caggcctagg ttggattcgt gtaacaggca tagcaaaagt cgccgtctgg gcaccagaag
    26881 gcgtcgccgt cgtcacacga aaagcaatta tttaaaacaa aatcgctgag cgaacaaagt
    26941 gagctcatat agcgatagtt attgccgtgg tgtgattgcc aatctgtaga ttggcaaggg
    27001 gcacaattga gaccaaggct caattgtgag gtcaggaaat ccatttttca aagatgaaat
    27061 ctttggaaaa ttagttccga ccgtccctca ccacctaaaa taactatcca aaaacaagga
    27121 agaaaattat gtcattaaca tcaaaacaac gtgccttcct caacagccag gcacacaccc
    27181 tcaaacctat catccaaatc gggaaaaatg gactcaacga ccaaatcaaa accagcgtcc
    27241 gtcaagctct tgatgcgcgt gaattaatca aggttactct cttacaaaac acagatgaaa
    27301 acatccacga agtagctgaa attttggaag aagaaatcgg tgtggataca gtccaaaaaa
    27361 taggacgcat cttgattttg tttaaacaat ctagcaagaa agaaaatcgc aagatttcta
    27421 agaaagtcaa agaaatctaa gaccgaaact ccaaataact gtttttatag agaaataaag
    27481 gggactagcc tatgacaatc gaactattga ctccctttac caaggtagag ttggagccag
    27541 aaatcaagga gaaaaaacgc aaacaagttg ggattttagg ggggaatttt aaccctgttc
    27601 acaatgccca tctcattgtt gcggatcaag tacggcaaca gttgggactg gatcaagttc
    27661 tgctcatgcc tgaataccaa cctcctcacg ttgataaaaa ggaaaccatc cctgaacacc
    27721 atcgtctcaa gatgcttgag ttggcaattg agggaattga cggcctagtc attgaaacca
    27781 ttgagttgga gcgcaagggt atttcctaca cctacgacac catgaagatt ttgacagaga
    27841 agaatccaga tacggattat tactttatca tcggcgccga catggttgac tatctgccta
    27901 agtggtaccg aattgatgaa ctggttgaca tggttcagtt tgtgggggtt cagcgtccac
    27961 gctacaaggt agggacttcc tatccagtta tctgggtgga cgtaccgctc atggatatct
    28021 cgtccagcat ggtgcgggac ttcattgccc aaggtcggaa acccaacttt ctcctacctc
    28081 agccagtgct agactacatc gagaaggagg ggctctactg atgtcctatc aagactatat
    28141 caactgctcc cgtgaggcct tgttggaaag aatggcagag cttctacctg agaaacgtct
    28201 aacccattgt ctaggtgtgg agcgtgccgc tatggaatta gctcagcgct ttggtgtaga
    28261 tgttgagaaa gcaagtctag caggtcttct tcatgactat gctaaaaagt tgtcagatca
    28321 ggaatttcta gacttgattg accgttacca gctagatttc gacctcaaaa actggggtaa
    28381 taatgtctgg catggtatgg tcggaattta caaaattcag gaagatttgg atttgcatga
    28441 ttcagaaatc ctgcgagcca ttgaagtcca tacagtcggt gctggtcaaa tgacagacct
    28501 agataaggtc atctacgtcg cagactatat cgagcacaat cgagcctttc ctggagtaga
    28561 tgtggcgcgt gagattgcaa gtctatcgct caataaggcg gtggcctacg aaacagctcg
    28621 taccgtggag tatctagctc atcagggatt ccccatctat ccccaaaccc ttgaaaccta
    28681 taacgccttt gtgcactatt tgaaagagaa ctaaatgaag acggctttta taatcattga
    28741 tgttcagaat gttttagtag aaactgggtt ccagacaaaa agtctattgg gaaaaatttc
    28801 ttatttacaa aaccaggcta gaagcaagaa tattgaaatt atctatgttc aacatattga
    28861 gaactctgaa gctcaaacat cagaagattg gcagttatct gcgcttttaa atcgaaaacc
    28921 tgctgaaaag gtctttcaga agaagtataa cagtattttc aaagaaactg gcttaaaaga
    28981 atacttggat aagcagggga ttgaaaaatt agttttatgt ggtatgcaga cagaatattg
    29041 tgtggatacc tctgtcaagg ttgcctttga atatggctat cagcttattg ttccagaagg
    29101 tgctgtcaca acctttgatg gggatgacat tccagcagaa acgattaatg aattttatga
    29161 ggacatttgg gaggagcgct ttgcagatgt cctagattac aaacatattt tctaaaaaga
    29221 ggattaaatg aacgaaaaag aattactaga actagtcgtg aaagcggctg atgagaaacg
    29281 tgcggaggat atcctcgcac ttgatgtaca agatttgact agtgtgacgg actactttgt
    29341 catcactagc tcaatgaata gccgtcagtt ggacgctatc gcagctaata tccgtgaaaa
    29401 agtagctcaa gcgggcttta aaggtagcca tgtcgaaggc gatgcagctg gaggctgggt
    29461 cttactggac ctcggtgctg ttgtcgtgca tatcttttca gaagaaatgc gtgcccatta
    29521 taatctagag aagctatggc atgaggcgaa ttcagtagat atttcagaag ctcttgctta
    29581 gaagatgaac tcagttgtag tcaactgggt ttctttgctt attttagaaa aattgataga
    29641 aaggtaaagg gctagtggtg tttaccatgg agctcttagt atcatgatta tggcgactta
    29701 tgaaaccttt gcggcggtct atgatgcggt catggacgat agtttatacg acaaatggac
    29761 aaatttttct ctgcgtcatt tgcctaagac caaggagaaa aagaaactct tggaactggc
    29821 ttgtgggaca ggaattcaat cagtgcgctt ctctcaggct ggttttgatg tgactggact
    29881 tgacttgagt gcggatatgt tgaagattgc ggagaagaga gcaacttcag ccaagcaaaa
    29941 gattgctttt atagaaggta atatgctaaa tttgtccaag gcagggaaat acgattttgt
    30001 cacgtgttat tcggactcta tctgctatat gcaggatgag gtggaagtag gggacgtctt
    30061 taaggacgtg tacaatgcgc tgaatgaaga gggagttttc atctttgacg tgcactcgac
    30121 ctaccagaca gatgaagtat tccctggcta ttcctaccat gaaaatgcgg aagatttttc
    30181 catgctttgg gatacatatg aggacgaagt tcctcactcc atcgtgcatg agctgacttt
    30241 ctttatcaag gaggctgacg gttcctttag tcgccacgat gaagtacatg aggagaggac
    30301 ctatgagatc ttgacctatg atatcttgct ggaacaggct ggattcaagt ccttcaaact
    30361 ctatgcagac tttgaggata aggagccaac agaaactagc acccgttggt tttttgtggc
    30421 gcagaagtag gagattagca tgaccatcac aggtattatc gcggagttca atccttttca
    30481 taatggccat aaatacctgc tggatcaggc agagggactg aaaattgttg ccatgtcagg
    30541 gaatttcatg cagcgtggag agcctgctat tgtggataag tggacaaggg cccagatggc
    30601 gctggaaaat ggcgcagact tggtagtgga attgcctttt ttagtcagtg ttcaggcagc
    30661 tgatttcttt ggtcaaggag ctgtggatat cttggatcgc ttgggcattg atagtctagt
    30721 ttttgggaca gaggaagttc gagattatca gaaaatcgct gacttataca cagagaaagg
    30781 tgctgagatg gagaaatttg tggaaaatct gcctgattcc ctttcctatc cccagaaaac
    30841 ccaagctatg tggaaggaat ttgctggtct tgatttttca ggtaataccc ccaatcatgt
    30901 tcttgctctg gcctatgcaa aggcggttgc aggacgaaat atcaagctgc atccgattca
    30961 gcgtcagggg gcaggttacc attctgtgaa taaagatgtg gactttgcct cggcgacagc
    31021 cctccgtcaa catcagaagg accaagattt cttagaacgt tttatgcctt ctgttgccct
    31081 atttgagcag gccagtaagg tgatctggga agactatttt cccttgctcc gctatcaaat
    31141 cttgtcaaat cctgacctaa ccaccatcta tcaggtcaat caagaaatgg ctgtgcgcat
    31201 taaagaagct attaaaacag cccagtctgt ggaagaattg gtcgagttag tgactaccaa
    31261 acgttacacc aaggcgcgtg tcagacgcct attgacctat attttgatgc aggctagaga
    31321 aagtgacttg ccagaagcca ttcatgtcct tggatttact gaaaaaggta ggcaacatct
    31381 caagtctttg aaaggtcagg tcagtctagt cagccgaatt ggcaaagaac cttgggatgc
    31441 tatgactcaa aaggttgacc agatttacca actaggaaag ccaagtatag cagagcaaaa
    31501 ttttggcaga gtgccgatta gaatagaaac aaactaagtc taccgaaagg tggacttttt
    31561 gagatttttt acgaataata ctcttcgaaa atcaaattca aatcgcgtca acgtcgcctt
    31621 gccgtactca agtacagcct gcggctagtt tcctagtttg ctctttgatt ttcattgagt
    31681 ataaatagat agaaaagaaa atcttgtaca agttcctgac aatttctttc ttttcgtgta
    31741 taatagtgga aaagagctaa aacgaggtat ggttatggaa gcagtccttt actcaacatt
    31801 ccgaaatcat ttaaaggact acatgaagaa ggtaaatgat gaatttgagc ctttgacggt
    31861 ggtcaataaa aatccagatg aggacattgt agttctttca aagagcgaat gggacagtat
    31921 tcaggaaacc ctgagaatcg cccaaaataa ggagttatca gacaaggttt tacgaggaat
    31981 ggataaaatt cgcgcaggac actagtctaa tttacagaga atacctgagt gaaatcttgc
    32041 tgttgttaga aacaaacttc ttgtatttca taatcattag gaagtctact gcaaagtagg
    32101 ctttttctca agtctctact aaactactat ttctaaaaaa caagtttatt ttggtaaatg
    32161 tgttccaaat tccccaaaac atattctatt ttaggtttgt gaaaatcact tttttatggt
    32221 agaatgtaaa agaatgtatg tcattcggaa taacaataaa atgaggtaaa aacatggagt
    32281 tcatgtcgct tgcgattgct gtttttgccg tcatcattgg tttagtcatt ggatatgtca
    32341 gcatctcagc taagatgaaa tcatctcagg aagctgcaga gttgatgctt ttaaatgctg
    32401 aacaagaagc aactaattta cgtggacaag ctgagcgtga agcggattta cttgttaatg
    32461 aagccaaacg tgaaagcaag tctcttaaaa aagaagcact attggaggcc aaagaagaag
    32521 ccagaaaata ccgtgaagaa gtggacgctg aattcaaatc agaacgtcaa gaactcaaac
    32581 aaatcgaaag tcgtttgaca gagagagcta ctagccttga ccgtaaggac gacaatttga
    32641 cgagtaaaga acaaacactt gaacaaaaag aacaaagtat ttctgataga gcgaaaaacc
    32701 ttgatgcgcg tgaagagcaa ttagaggaag tcgaaagaca aaaagaagca gaactagagc
    32761 gtattggtgc tctgtctcag gcagaagcac gagatattat cttggctcag acagaggaaa
    32821 acttgaccag ggagattgcc agtcgcattc gcgaagctga gcaagaggtc aaggaacgtt
    32881 ctgacaaaat ggccaaggac atcttggttc aagctatgca acgtatcgct ggtgaatatg
    32941 tagcggagtc aacaaactca acagttcatc tgccagacga tactatgaag ggacgcatta
    33001 ttggtcgtga aggtcgtaac attcgtacct ttgaaagttt gacaggggtc gatgtgatta
    33061 tcgacgatac accagaagtg gtgaccttgt caggatttga tccgattcgt cgtgagattg
    33121 cccgtatgac tatggaaatg ttgctcaaag atggtcgtat acatccagct cgtatcgaag
    33181 agttggttga gaaaaaccgt caagagattg acaataagat tcgtgaatac ggtgaggctg
    33241 ctgcctatga aattggtgcg ccaaaccttc atccagactt gatgaagatt atgggacgtt
    33301 tgcagttccg tacttcatat ggacaaaatg ttttgcgcca ttcgattgag gttgctaagt
    33361 tggctggtat catggcgagc gaacttggtg aaaatgcggc tcttgcccgt cgtgctggat
    33421 tccttcacga tatcgggaaa gccattgacc atgaggttga aggtagccac gttgaaatcg
    33481 gtatggaatt ggcccgtaag tacaaggaac ccccagttgt ggtgaatacg attgctagtc
    33541 accacggaga tgttgaagct gagagcgtga tagcagttat cgtcgctgca gcagatgcct
    33601 tgagcgcagc ccgtccaggt gctcgtagtg agtctcttga aagctacatc aagcgtctcc
    33661 atgatttgga agaaattgct aacggctttg aaggagtgca aactagcttt gcccttcaag
    33721 caggacgtga aattcgtatc atggtcaatc caggaaaaat caaggacgac aaagtcacaa
    33781 tcttggctca caaagttcgt aagaaaattg aaaacaatct cgattatcca ggaaatatca
    33841 aggtaaccgt gattcgcgag cttcgtgcag tagattatgc taaataaata agaaagagca
    33901 gttgaaaaat tactgctttt ttgttacact agatagaaag actgtaaagg ataatctggc
    33961 tttttgccat tattctagag aaatgttatt tcacagattg actaaaagga gacacaatgg
    34021 cagaccgagg cttactaatc gttttttctg gtccttcagg ggttggaaaa ggaacggtta
    34081 gaagagagat ttttgagagt tctgaaaacc aatttcaata ttctgtatcg atgacgacac
    34141 gcgcacaacg tcctggagaa gtggacggtg ttgactattt cttccgtact cgtgaagaat
    34201 ttgaagagct gattcgtcaa ggacagatgt tggaatacgc agaatatgtc ggtaactact
    34261 atggaactcc tctgacctat gtcaatgaaa ccttggacaa gggaatcgat gttttccttg
    34321 aaattgaagt tcagggtgct cttcaggtca agaaaaaggt tccagatgct gtctttatct
    34381 tcctgacacc accagatttg gatgaattgc aagatcgctt ggtaggtcgt ggaacagata
    34441 gtgcagaagt gattgcccaa cgaatcgaaa aggccaagga agaaattgcc ctcatgcgtg
    34501 agtatgatta tgcgattgtc aacgatcagg tgcccctagc tgctgaacgt gtcaaatgtg
    34561 tgattgaagc agaacacttc tgtgtggatc gtgtcattgg tcactatcag gagatgttac
    34621 caaaatctcc aactacccga taaaatttag aaaataggta caagcaaatg atgttaaaac
    34681 cctctattga taccttgctc gacaaggttc cttcaaaata ttcactcgta atcttggaag
    34741 caaaacgtgc ccacgaattg gaagcaggtg ccccagcaac tcaaggtttc aagtctgaaa
    34801 aatcaactct tcgcgcttta gaagaaatcg aatcaggaaa cgttacaatt cacccagatc
    34861 cagaaggaaa acgtgaagca gtgcgtcgcc gtatcgaaga agagaaacgc cgcaaagaag
    34921 aagaagaaaa gaaaatcaaa gagcaaattg ctaaagaaaa agaagatggt gaaaaaattt
    34981 aaggttgggg ggactcaatc ttattttttc tattgcaaga atgtactgac aaggaggagg
    35041 tgagaagatg gccctagcta agattatcgt agatgtgccc ttgatgcaga cggaccagcc
    35101 ctatagttac aggattccgg aggaatttga gggaatgctg gaagttggga tgcgggttca
    35161 tgtacctttt ggtaagggta atcgcctgat tcaagggatt gttcttggtt tggagtccca
    35221 atcagatgga gaagagatgg agcaagattt aaaagatatt gcagaggtgc tggatttttc
    35281 tcctgttctc acgccagaac aactctggct ggctgaggag ttacgcaaat ctgtcttctc
    35341 ctacaaaatc tctatcctca aggccatgct tccaggattt ctgaattcta gctatgacaa
    35401 gattctctat cctctggaag gcttgagtca ggaagaacga gtacgcctgt ttggttcaga
    35461 agattcgcta gccttttctt cactagacct tgccaagcaa gctgaaatga tgcgtttgac
    35521 tagaaaaggc ctgcttggtc tggaatatca ggcagtcgat caaaagaagg tcaagaccca
    35581 gtcttggtat gaggttgacc atgcccaatt agaaggtgtt gagatttcta cacgtgccaa
    35641 gaaaaagttg gaactgagag attatctgct gtctcatcca gagagcgctt ccttggctag
    35701 cttgttagag tcctactcgc gagagcaagt caacttcttt gtggatcaag gtgctgttac
    35761 catagtccaa aaggaagttc aacgctcggc tgcttatttt gaaggaattg aagcaagtag
    35821 acctttggag ttaaatccag aacaaagaca ggcgcgtgat gcggttgtga gttctattgg
    35881 cagttctcaa cctccctttc tacttcaagg gattacagga agtgggaaga ccgaggttta
    35941 cttgcagatt atccaaggtg ccctggataa gggcaagaca gctattttgc tggtacctga
    36001 gatttccttg actcctcaga tgaccgagcg ttttatagca cgttttgggg acaaggtagc
    36061 cattcttcac tcaggattat ccaatggtga aaagtatgat gaatggcgca aggtggagcg
    36121 tggcgatgcc caagttgttg ttggtgccag atctgctatc tttgctcctc tgaaaaatct
    36181 gggtgtcatg attattgatg aagagcatga agcggcttat aagcaggaca gcaatccccg
    36241 ttaccatgcc agagaggtag ctattttacg ggctcagtat aatcaagcaa ctctggtact
    36301 tggatctgca acgccgagct tagagagccg ggcgcgtgct ggcaaaggcg tctatcaaca
    36361 cttacgtcta acccaacgtg ccaatccttt ggctacaatc cctgaggttc aagtgattga
    36421 ctttcgagac tatatcggac aaaatgagac gtcaaacttt acgcctcctt tgctagaggc
    36481 tatccaagac cgtctggtta aaaaagagca ggtggttctc atgctcaatc gccgtggtta
    36541 ttctagcttt gtcatgtgtc gggagtgtgg gacggtggat acttgtccca actgcgatat
    36601 ttctctgacc ttgcatatgg ataccaagac tatgaactgc cattattgtg gtttctcgaa
    36661 ggatattcct caggtctgtc ctaactgtaa gagccacagt attcgttact atgggacggg
    36721 aactcagaag gcttatgatg agctagcaga actctttccc caagctcgca ttctgaggat
    36781 ggatgtggat acgactcgaa aaaaaggcag tcaccaagcc ttgcttgatc agtttgggcg
    36841 agggaaagcg gatattttac ttggtactca gatgattgca aagggtttgg attttcccaa
    36901 tgttacccta gtcggagttc taaatgcgga tacggccttg aatctgcctg atttccgttc
    36961 ttctgagaga accttccagc tcttgactca ggtggcaggt cgagcaggtc gggctgaaaa
    37021 agcaggtcaa gtcttgatac agtcctacaa ttcgcagcac tatgctattc gatttgccaa
    37081 ggatcaagat tacgaaggct tttatgccta tgaaatggga atcagacgac aactcggcta
    37141 tccaccttac tatttcacga ttggtattac cctttctcac aagaaagaag aagaggtttt
    37201 caaacgtgcc tatgaagtca tgaacatttt gcggtcaggc ttgtcagaga ccagtcccat
    37261 tctggggcca acgccaaaac cgattgcccg tacccacaac ctctatcatt accagatttt
    37321 aattaaatac cgtttagaag atgagctggg gccgaccctc aaccaggtct tggccttgac
    37381 tcaagaacgg gaaaatagtg agctccgtct cagcattgac catgagccgc agcaattttt
    37441 ataaaaagga gaagatatga caaaactaat ctttatgggg acccccgact tttcagcaac
    37501 agtcttaaaa ggacttttga cagatgaccg ttacgaaatt ctagccgttg tgacccagcc
    37561 agaccgtgct gttggtcgta aaaaagttat ccaagaaacc ccagtcaagc aggctgccaa
    37621 ggaagcagga ctatctatct accaacctga aaaattatct ggaagtccag agatggaaga
    37681 tcttatgaag ctaggagcag atggaattgt gactgctgct tttgggcagt ttctcccaag
    37741 caaactcctt gatagcatgg actttgctgt caacgttcat gcctccctcc ttcctagaca
    37801 ccgtggtggt gcgcctatcc attatgcctt gattcaaggg gatgaggaag ctggtgtgac
    37861 catcatggaa atggttaagg aaatggatgc aggagatatg atttctcgtc gcagcattcc
    37921 gatcacagat gaggacaatg ttggcacctt gtttgaaaaa ttggcgctag ttggtcgtga
    37981 tttgcttttg gacactctgc ctgcctatat tgctggtgat atcaaacctg aaccgcagga
    38041 tacgagtcag gttaccttct ctccaaatat aaagccagag gaagaaaaac tggactggaa
    38101 caaaaccaat cgtcaactct ttaaccaaat tcgtggaatg aacccctggc ctgttgccca
    38161 tactttcctt aagggcgacc gctttaagat ttatgaagcc ctaccagtag aaggtcaggg
    38221 aaatccaggt gagattctct ctatcggcaa gaaagaattg attgtcgcaa cggctgaagg
    38281 ggctctatcc ctcaaacaag tgcagccagc tggtaagcct aagatggaca ttgcttcctt
    38341 cctcaacgga gttggacgta cattgactgt aggagaacga tttggtgact aaagtagaaa
    38401 cggctagaag tttagctcta gcagtgctag aggatgtttt tgtgaaccaa gcatactcaa
    38461 atatcgcctt aaataagcat ctaaagggaa gtcaactttt ggcagcagac aagggcttag
    38521 tgaccgagct ggtctatgga acggtagccc gtaaactgac tctggaatgg tacctatccc
    38581 actttatcga agacagagac cagttagaca gctggctcta tgtccttctt ctcatgagtg
    38641 cctaccaact ccgctatttg gacaagattc cagatcatgc tgtggtcaat gaagcagtgg
    38701 aattggccaa acttcgtaaa aaaggcagtg aaaaattggt caatgccctc cttcgccgta
    38761 tcttgcgtga aggctggcca gatatttcta gcatcaagcg aaaaaacaag cgtgactcca
    38821 ttgcctattc tctcccagtt tggctagttg ccaaactcaa ggaagaatac ggagaggaga
    38881 gagcaaaagc catctttgaa agcttgttag tgcgaaacaa agccagtatt cgtgtaacag
    38941 acctaagtcg aaaagaggaa atccaagcct tgttggaggc gaataattcc cttttagcaa
    39001 ccactggtct ggttaaggag caggggcatt ttgcagggca taatttgttt gcggatggag
    39061 ccattaccat ccaagacgag tccagtcagc tggttgctcc gacgcttgat ttacaaggtg
    39121 atgagcgagt gcttgatgcc tgtgcggctc caggtgggaa aacagcccat atagcctctt
    39181 atcttacgac aggtcaggtt actgctctgg acttgtacga ccacaagttg gatttaattc
    39241 aagaaaatgc ccaacgtctg ggagttgcag atcgggttca aactcaaaaa ttggatgcca
    39301 gaaaggtgca tgagtttttt gaccaggatt cctttgataa gattttggtg gatgctcctt
    39361 gttcaggaat cggtcttttg cgccgaaaac cagatatcaa atacaataaa gaaacggcag
    39421 atttcgcgtc cttgcaggaa attcagttag aaatattagg tagtgtttgt caaatactag
    39481 gcaaaggtgg tataataact tatagcacct gcactatcgt ctcagaggag aattttcaag
    39541 tcgttaaggc ctttttagag agtcatcccg agttcgagca ggtaaaacta gaacatgaat
    39601 gtaaggatat catgaaagac ggctgtatcc tcattacacc tgaattgtat ggaagtgatg
    39661 gattcttcat cagtcaattt cgcaagatat cggattagga aggaactgac acatggaaat
    39721 ttcattatta acagatgttg gtcagaaacg aacaaataac caagactatg tcaaccacta
    39781 tgtcaataga gctggacgta ccatgattat tttagctgat gggatgggag gtcatcgcgc
    39841 agggaatatc gctagtgaaa tggcggtcac agacctgggt gtagcttggg ttgatactca
    39901 gatcgataca gtcaatgaag tgcgtgaatg gttcgcccat tacctagaaa ttgaaaatca
    39961 aaagattcac cagcttggtc aggatgaagc ttacagaggc atgggaacta ctttggaagt
    40021 ccttgctatt attgataatc aggctatcta tgctcatatt ggtgattcgc gtatcggctt
    40081 gattcgtgga gaagaatacc atcagttgac gagtgatcat tctttggtta atgaattgct
    40141 caaggctggt caattgacac cagaagaggc agaagctcat ccgcaaaaaa atattatcac
    40201 ccagtctatt gggcaaaaag atgaaattca gcctgatttt gggacagtta tccttgagtc
    40261 aggtgactat ctcttgctca atagtgacgg cttgaccaac atgatttcag gcagtgagat
    40321 tcgtgatatt ataaccagtg atattccttt agcagataaa acggagacac ttgttcgttt
    40381 tgctaacaat gcaggaggtt tagacaacat tacggttgcc cttgtttcta tgaacgagga
    40441 ggatgaagaa tgatccaaat cggcaagatt tttgccggac gctatcggat tgtcaaacag
    40501 attggtcgag gaggcatggc ggatgtctac ctagccaaag acttaatctt agatggggaa
    40561 gaagtggcag tgaaggttct gaggaccaac taccagacgg acccgatagc tgtagctcgt
    40621 tttcagcgtg aagcgagagc tatggcagat ctagaccatc ctcatatcgt tcggataaca
    40681 gatattggtg aggaagacgg tcaacagtat cttgcaatgg agtatgttgc tggactagac
    40741 ctcaaacgct atatcaagga acattatcct ctttctaatg aagaagcagt ccgtatcatg
    40801 ggacaaattc tcttggctat gcgcttggcc catactcgag gaattgttca cagggacttg
    40861 aaacctcaaa atatcctttt gacaccagat gggacggcca aggtcacaga ctttgggatt
    40921 gctgtagcct ttgcagagac aagtctgacc cagactaact cgatgttggg ctcagttcat
    40981 tacttgtcac cagagcaggc gcgtggttcg aaggcgactg tgcagagtga tatctatgcc
    41041 atggggatta ttttctatga gatgttgaca ggccatatcc cttatgacgg ggatagcgcg
    41101 gtgaccattg ccctccagca tttccagaaa cccctgccgt ccgttattgc agaaaatcca
    41161 tctgtacctc aggctttaga aaatgttatt atcaaggcaa ctgctaaaaa gttgaccaat
    41221 cgctaccgct cggtttcaga gatgtatgtg gacttgtcta gtagcttgtc ctacaatcgt
    41281 agaaatgaaa gtaagttaat ctttgatgaa acgagcaagg cagataccaa gaccttgccg
    41341 aaggtttctc agagtacctt gacatctatt cctaaggttc aagcgcagac agaacacaaa
    41401 tcaatcaaaa acccaagcca ggctgtgaca gaggaaactt accaaccaca agcaccgaaa
    41461 aaacatagat ttaagatgcg ttacctgatt ttgttggcca gccttgtatt ggtggcagct
    41521 tctcttattt ggatactatc cagaactcct gcaaccattg ccattccaga tgtggcaggt
    41581 cagacagttg cagaggccaa ggcaacgctc aaaaaagcca attttgagat tggtgaggag
    41641 aagacagagg ctagtgaaaa ggtggaagaa gggcggatta tccgtacaga tcctggcgct
    41701 ggaactggtc gaaaagaagg aacgaaaatc aatttggttg tctcatcagg caaacaatcc
    41761 ttccaaatta gtaattatgt cggccggaaa tcttctgatg ttatcgcgga attaaaagag
    41821 aaaaaagttc cagataattt gattaaaatt gaggaagaag agtcgaatga gagtgaggct
    41881 ggaacggtcc tgaagcaaag tctaccagaa ggtacgacct atgacttgag caaggcaact
    41941 caaattgttt tgacagtagc taaaaaagct acgacgattc aattagggaa ctatattgga
    42001 cggaactcta cagaagtaat ctcagaactc aagcagaaga aggttcctga gaatttgatt
    42061 aagatagagg aagaagagtc cagcgaaagc gaaccaggaa cgattatgaa acaaagtcca
    42121 ggtgccggaa cgacttatga tgtgagtaaa cctactcaaa ttgtcttgac agtagctaaa
    42181 aaagttacaa gtgttgccat gccgagttac attggttcca gcttggagtt tactaagaac
    42241 aatttgattc aaattgttgg gattaaggaa gctaatatag aagttgtaga agtgacgaca
    42301 gcgcctgcag gtagtgtaga aggcatggtt gttgaacaaa gtcctagagc aggtgaaaag
    42361 gtagacctaa ataagactag agtcaagatt tcaatctaca aacctaaaac aacttcagct
    42421 actccttaaa agcagatgga taatcaaaat gagtaatcaa tctttgtcat gatttcatgg
    42481 caaagatttt ttttgagtcc agatttgtga tagaatagag ggagttgata aaaggaggaa
    42541 agcatggaag aatcaaaaga attaaatgcc gtcattgatg tgattatgct agcggggact
    42601 attctcctta aaagtggctc agaaatccat cgtgtagaag ataccatgat tcgaatcgcg
    42661 cattcgcagg ggattgtgga ttgcaatgtc cttgccatgc ctgccgctat ctttttctct
    42721 attgaaaata ccaatatttc gcgcatgaag cgcgtgacct cctcttctta taacatcgaa
    42781 aaagtctgcg atgtgaacca gatttctcgt cagctagttg gggggcagat tgacttagaa
    42841 acagccttta agcaattgac ggccttgcaa gctcaacccc ttccctatac taagttgcag
    42901 gtaactctgg ctgcgacctt tagtgctcct ttcttttcag ttatgtttag cggaaatatc
    42961 tacgacgcac ttggggcagg agtggcgacc ttatttggtt ttgccttttc cctctatgtg
    43021 gaaaaattta tccgaattcc ctttgtgaca gcctttgctg gagcctttgt ctttgggata
    43081 attgcccagt tttgggctcg ctacacaggt tttccttcaa cggcagattt gattatagct
    43141 ggtgcggtca tgccgtttgt accaggtatt gccttgacca atgcggtccg tgatattatg
    43201 accaaccaca taaactctgg tatgagtaag atgtttgaat ccctgctcat taccctcgct
    43261 ttaggggcag gaacttctgt cgccttggta ttgatgaact aatatgacac taacaacctt
    43321 tttattacaa gcagtagcaa gttttcttgc cattatcact tttttaatcg tactcaatgt
    43381 gcaacggtct atgctcttac ctggagggat tttgggcatg actgtctggc taatctatct
    43441 cttgctcaag gaaccgacca atgtcattgt agctaccttc attgcagcca ttattggttc
    43501 ttgtgtcagc cagattttaa gtattcttta taagacacct gctgtggtct ttatcttggc
    43561 cattttggca ccgctggttc caggttatct ctcctaccga acaactgcct tttttgtgac
    43621 aggggactat aataaagcac tggcaagtgc gaccttggtt gtcatgttgg ctttggtaat
    43681 ctctattgga atggctagcg gaacagtgat tctcagactg tatcattata taaaaacaca
    43741 tcgagtatcg tagactttac agaaataaaa gaattttctg aaaaatgaga taaataaatt
    43801 aacaacgctt tctatatgtg cgagaatacc gcacttatga agaaattgcg gctgattttg
    43861 gtatccacga aagcaactta ctccgtcgga gccaatgggt tgaagtaact cttgttcaaa
    43921 ggtggtgtta cgatttcaag aactcctctc agttctgaag acacggtaat gattgatgcg
    43981 acggaagtaa aaatcaatcg ccctaaaaaa aacaattagc gaatgattct ggtaaaaaga
    44041 aatttcacgc tatgaaggct caagcgattg tcacaagtca agggagaatt gtttctttgg
    44101 atatcactgt gaactattgt catgatatga agttgttcaa aatgagtcgc agaaatatcg
    44161 gacaagctgg taaaatcttg gctgacagtg gttatcaagg gctcatgaag atatatcctc
    44221 aagcacaaac tccacgtaaa tccagcaaac tcaagccgct aacagttgaa gataaagcct
    44281 ataaccatgc gctatctaag gagagaagca aggttgagaa catctttgcc aaagtaaaaa
    44341 cgtttaaaat gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga
    44401 atttgattgc tggcattatc aatcatgaac taggattcta gttttgcagg aagtctacta
    44461 ctttccttat tgtctgtaaa tctactgacc ttgttgttta tcccagtcat ggtttctagt
    44521 tcgggctcag agtttcaaag tggatggcaa gagcatcaat tgattgctga gaaggttagt
    44581 aaaacacttg ataagacatt tgataaggat gtcagagaaa ttccgaccag tcagttttat
    44641 caaaaatttg tagatgagat gggaaggact tactcaggaa atttgatcct ccaggagctg
    44701 ataactgtga atggagctta taaagctact tatatcggtg aactctctag caactaatca
    44761 ttctttaaaa tgatgaccaa taagaggctt gatttggtga atcaagtctt ttttctctct
    44821 tttactgcca tttgtgataa aatagtatag aacgattttt tacatgaatg ataaaacaga
    44881 ggtaaatatg acaatcggta ttgataagat tggttttgcg accagtcaat atgtcttgaa
    44941 attacaagac ttagcagaag cgaggggaat tgaccctgaa aaattaagta aaggactctt
    45001 actcaaggaa ttgagtattg cgcccctaac tgaggacatt gtgaccttgg cggccagtgc
    45061 tagtgactct attttaactg agcaagaaag acaagaagtt gacatggtca ttgtggctac
    45121 cgagtcagga attgaccaga gtaaggctgc ggccgtcttt gtgcatggct tgctgggcat
    45181 ccagcccttt gctcgtagtt tcgagattaa agaagcctgt tatggagcga ctgctgccct
    45241 tcattatgcc aaattgcatg tggaaaattc tccggagtcc aaggtcttgg tcattgccag
    45301 tgatattgcc aaatacggta ttgaaactcc aggagaacca actcaaggtg ctggaagtgt
    45361 agctatgttg attacacaaa atccacgcat gatggccttt aataatgaca atgtagctca
    45421 gacccgtgac atcatggatt tctggcgacc aaattactcg acaactcctt atgtaaatgg
    45481 tgtttattct acccaacaat acttggatag tttgaaaacg acttggcttg aatatcaaaa
    45541 acgctaccag cttactctgg atgattttgc ggctgtttgt ttccacttgc cttatcctaa
    45601 attagcgcta aaaggcttga aaaaaatcat ggataagagc ctgcctcaag agaaaaaaga
    45661 cctcttacaa aagcattttg accagtctat tctctacagt caaaaggtgg ggaatatcta
    45721 cacaggttca cttttccttg gacttttgtc tctcttggaa aatacagata gcttgaaagc
    45781 tggggataaa atcgcccttt atagttacgg aagtggagct gtggctgagt tcttcagtgg
    45841 tgaattggtt gaaggatatg aagcttattt ggataaagac cgtttgaaca agctcaacca
    45901 acgaactgcc ctatccgttg cagactatga aaaggtcttt tttgaggaag taaacttgga
    45961 tgaaacaaac tctgcccagt ttgctggcta tgaaaatcaa gattttgcct tggttgaaat
    46021 tcttgaccac caacgccgtt atagcaaggt tgaaaaataa tgaagataag ttggaatgga
    46081 ttttctaaaa aatcatacca agagcgcctc gagctgctaa aagctcaggc gctccttagt
    46141 cctgagagac aagctagtct ggagaaggat gaacagatga gtgtgactgt ggcagaccag
    46201 ctgagtgaga atgtggtggg aactttttct ctgccttatt cgctggttcc ggaggtactt
    46261 gtcaacggtc aggaatacac cgttccctat gtgacagaag aaccctctgt ggttgcggcg
    46321 gccagctatg ccagcaaaat catcaagcgt gcaggtggtt ttactgcaca agtccatcag
    46381 cgccagatga ttgggcaggt agccctttat caagttgcta atcctaaact agcgcaagag
    46441 aagattgcca gcaagaaagc ggagctcttg gagcttgcca atcaagccta tccttctatc
    46501 gttaaacgtg ggggtggggc gagtgacctg catgtcgagc agataaaagg tgaaccagac
    46561 tttctcgttg tttatattca tgttgatacc caggaagcca tgggtgccaa tatgctcaac
    46621 accatgctgg aagccttgaa accagtctta gaagaactca gtcagggaca gagtctcatg
    46681 ggaatcctgt ccaactacgc gaccgattct ctggtgactg caagctgtcg catggccttt
    46741 cgctacttga gccgccaaaa ggatcaagga cgagagattg cggagaaaat tgcattggct
    46801 agtcagtttg cgcaggctga tccttaccga gctgctactc ataataaagg aatttttaat
    46861 ggtattgatg cgattttgat tgccactggt aatgactggc gtgccatcga agctggggcc
    46921 catgcctttg ccagtcgaga tggacgctat caaggtctta gctgctggac gctggacctt
    46981 gaaagagaag aattggtcgg tgagatgacc ctgcccatgc ctgtagcgac taagggtggc
    47041 tctatcggcc tcaacccacg tgtagctctc agtcatgatc tactaggaaa tccttctgcc
    47101 agagaattag cccagattat cgtgtccatc ggtcttgctc aaaattttgc agccctcaaa
    47161 gccttggtaa gtacgggcat ccagcaaggc cacatgaaac tacaggccaa atccctagct
    47221 ctcctagctg gggctagtga atctgaagtt gctcccctag tagagcgcct catctcagat
    47281 aaaaccttta acctagagac agcccagcgc tatctcgaaa atttaagatc ataaaaactc
    47341 agacgaatcg gtctgagttt tcttgtgttt aaatactttt tcctggtaat agcgtaactg
    47401 gtaagaagta accagttgtg gcgacttcct tgccttcaat cttttgcaag agaagatcaa
    47461 tagtgagaca agcaatctct tccaaaggtt gcttgatagt agccaattga gggtagtaat
    47521 tttcgataaa gtaggtccca tcatagccga tgaccttgag ctcttttggg acagaaatgc
    47581 ccaattcttg agcgatttta atgaccagaa tagctgtcaa atcatccgaa gcaaaaatgg
    47641 catctggttt ttcccgggtc aagatattct tgatttccat ttcttttctg acgggagaaa
    47701 agtcactgga aacattgata ataggagctt ttgggagtac ggatgcaaaa ccagcgtggc
    47761 gcagtccggt tggcgaattg gaattgtcat tccctgtaat catgatgata gactgggcac
    47821 ctgtcttgac caaggtttgg gcagcaagaa ccccaccagc atagttgtca gaggagacga
    47881 cagggatgtc tggcgatagg tttcggtcaa aggaaataat cggcgctgtc acacgattgt
    47941 agtcttcgat tcctaggttg tgactaccag aaatgatgcc gtccacctga ttggcttcca
    48001 acatttcgat gtattcgcgt tccttctcag aatcatgttc actgttgcag atgatggtct
    48061 tgtaaccatt tttgaagagt tggtgttcca atttatcaat caattctgca tagaaaacat
    48121 tggaaatatt ggggaaaatc aagccgatta acttagctga ttttccttgc agactacgag
    48181 ccaggttgtt gggtttatag cccaattctc gcatggcttc attgactttt tggatggttt
    48241 tctcagatag ataccctttt ttattgataa cccgagaaac ggtagtagga ctgacgcctg
    48301 caagtttggc gacatcagtt agttttgcga ccataatcta attcatagta agttccagtt
    48361 gggtttccag atttgatcag gataccattt tggtccgcat gtgggaagac acgaccagaa
    48421 aatacttttt ctcctttatt gatgaaaatt tcaaagacag agttatcgat gaagattgta
    48481 gcagtagtag cctgattctc gatagggcaa gaacgagttg tcccaaattc ttgggcatac
    48541 tgttctccag cctggctacg atccactgtc acttgactgt ttacaagatc aaagttgatt
    48601 gaaagtccct taccttcttt atcagcaagt aagacaatct cgctctggct attagcttcc
    48661 aagttgagtt caagttcgta agtgttcttg gtttgggaac ggtttgagaa ggcttcttca
    48721 gaagcacgaa ggtccttaat agcagcgact ggatactggt agagcttgtc gtctttgata
    48781 gtgagttcct tgaccaaaga gaaggttcct tggtggtcaa aacggtcaga tgggtaagaa
    48841 acatctggca aaccaagcca gctaactgct agaacacgcc catcaggagc gttgaaggct
    48901 tgagttgcat aggcttcgaa accgtaatcc atgttttgaa gttgagacac atctaccatt
    48961 ttggcatttt tagggtcaaa ggaagcccca atcttataca tatttggaaa gatattatcg
    49021 tagtctagaa ctttcttatc caatccttgt ggacagtaga gaaggacagg ctgttcctct
    49081 acaaagacca gattaggaca ttccatcatg taggcagtac ggtcgttagc aaagtcaagg
    49141 tcgccaactg cttgccagtt tgtgtagtcg ttattgatag ccttgtagag acggacgaag
    49201 ccttttttct ccaagtcctg tccaccgacg acagcatagt attgaccttt aaagttaaaa
    49261 atttgtggat cgcggaagtg gtcagtagag tctgctggct ggtcaatcaa gatcttgtca
    49321 atctttgtaa tcttaccctc cttgtccatc aaagcaccga tctggtatgg gtgacggatc
    49381 cagttttcat cgcgaacatt tcctgtataa aataggaata agttatcgcc aaatttcatg
    49441 gcagaaccag agtaggcacc gtggctatct aatggagtat ctggtaaaac tttgattcca
    49501 gtttctttaa agtgaaccaa atcatcactt tctagctgtg cccaagattt caaaccgtgg
    49561 gctgcaccaa aaggaaaatt ctggtaaaag aggatccact tgccatcaaa gtaagaaaag
    49621 ccatttgggt cgttgagaag tcctgttttt ggctcaacat ggtaatgagt atgccatgga
    49681 gattgtgcca tattttcctt tatatgttga atttcttctt gcgtccaatc ttgataaagt
    49741 ctgtaacgac gctcagttgt ccattccatt cattcctcca aaaatcttat cacttttaat
    49801 agtaactgtt ttcgataaaa aatgcaagcc ttttatatta aaaaagagga aaaactgtca
    49861 aacgattatc ataaaataaa tacaggaaat caattaaatt tttacgaaaa tgtgaaagat
    49921 aatgaaataa aagacttttt aaccaaggtt tcaaacttgt ttttcaagga attcctgatg
    49981 aaacagtcaa aaacaatcaa tctaaagctt gctcactaag tggatagaat attttttctg
    50041 caaaacgctt gacatatttt taaaacatga taaaataata gtcgtaaggg cgaataaaat
    50101 cgctttcaaa caagaacaaa atgttatata aggagatttt tgcaaatgaa caatcaggaa
    50161 attgcaaaaa aagtcatcga tgccttgggc ggacgtgaaa atgtcaatag tgttgcccac
    50221 tgtgcgactc gtctacgtgt catggtcaaa gatgaagaga aaatcaataa agaagtgatt
    50281 gagaacttgg aaaaagttca aggtgctttc tttaactcag ggcaatacca aattatcttt
    50341 ggtacaggta cagttaacaa aatgtacgat gaagttgttg tacttggctt accaacatca
    50401 tctaaggatg acatgaaagc agaagttgct aaacaaggga actggttcca acgtgctatc
    50461 cgtactttcg gtgatgtttt cgttccaatc atcccagtta tcgtagcgac aggtctcttt
    50521 atgggtgtgc gtggtctttt caacgctctt gaaatgccac ttccaggtga ctttgcaact
    50581 tacacacaaa tcttgacaga tacagccttc atcatcttgc caggtttggt tgtgtggtca
    50641 accttccgtg tatttggtgg aaatcctgcc gttggtatcg ttcttggtat gatgcttgtc
    50701 tctggctcac ttccaaacgc ttgggcagtt gctcaaggtg gtgaagtaac agcgatgaac
    50761 ttctttggtt tcatccctgt tgttggtttg caaggttccg ttcttccagc cttcatcatc
    50821 ggggttgtcg gagctaaatt tgaaaaagct gtccgcaagg ttgttccaga tgtcattgac
    50881 ctcttggtaa caccattcgt gacacttttg gtcatgtcta tccttggact ctttgtcatt
    50941 ggaccagttt tccacgttgt tgaaaactac atccttattg ctacaaaagc gattcttagc
    51001 atgccatttg gtcttggtgg tttcttgatt ggtggggttc accaattgat cgtcgtgtca
    51061 ggtgtgcacc acatcttcaa cttgcttgaa gtgcaattac ttgctgctga ccatgctaac
    51121 ccattcaacg ctatcatcac agctgctatg acagctcaag gtgctgctac tgttgcagtt
    51181 ggtgttaaaa caaaaaatcc aaaactgaaa acacttgctt tcccggctgc tctttctgcc
    51241 tttctaggta ttacagagcc tgctatcttc ggggtgaact tgcgcttccg taaaccattc
    51301 ttcctttcat tgattgctgg tgcaatcggt ggtggattgg cttctatcct tggacttgct
    51361 ggtactggta atggtatcac catcatccct ggtacaatgc tttatgttgg taacggacaa
    51421 cttccacaat accttcttat ggtagctgta tcatttgccc ttggttttgc tcttacttac
    51481 atgtttggtt acgaagatga agtagacgca actgcagctg caaaacaagc tgaagtggct
    51541 gaagaaaaag aagaagttgc gccagcagct cttcaaaatg aaacacttgt aactcctatc
    51601 gtcggtgatg ttgtcgctct tgctgatgtc aatgacccag tcttctcaag tggagctatg
    51661 ggacaaggta tcgctgtgaa accaagccaa ggcgtggtct atgcaccagc tgatgctgaa
    51721 gtttcaattg cctttccaac agggcacgct tttggtttga aaacaagaaa tggtgctgaa
    51781 gttttgattc acgttggtat tgacactgta tctatgaacg gtgacggttt tgaagcaaaa
    51841 gtttctcaag gtaataaggt gaaagctggc gatgttcttg gaacatttga ctcaaacaaa
    51901 atcgctgcag ctggacttga tgatacaaca atggttatcg ttacaaatac agctgactac
    51961 gcttcagtag ctccagtcgc aacaggttca gttgcgaagg gggatgctgt gatcgaagtg
    52021 aaaatctaat caatcctctc taatgtgaaa acgaacaaat gacatgtttg ttcgttttta
    52081 ttagatagta agatttacag aggaaaatct aaaaaataga gacatttaga ctttcgaagt
    52141 atgctataat aaagaaaata aaaacaagag gtttatcatg acaaaattat atggaagctt
    52201 ggaagcgggc ggtacaaagt ttgtctgtgc tgtcggtgat gaaaacttta acgttgtaga
    52261 aaaaacacaa tttccaacaa caactccaat cgaaacaatc gataaaacca ttgagttctt
    52321 ctcaaaattc gataaccttg ctggtcttgc agttggttca tttgggccga ttgatattga
    52381 caaaaactca aaaacttatg gctttatcac gacgactcca aaaccaaact gggcaaatgt
    52441 ggacttgctt ggtgcccttc gtcgcgccct aaacgtgcca atgtacttca caacagacgt
    52501 aaacagctct gcttacggtg aaatggttgc ccgtaacaat gctggtggtc gtatcgaaaa
    52561 cttggtttac tacacaatcg gtacaggtat cggtgcaggc gtcatccaac gtggtgagtt
    52621 tatcggtggt gtgggtcacc ctgaaatggg tcattattat gttgctagac acccaatgga
    52681 tattgaaaaa gagtttaagg gtgtttgtcc tttccataag ggatgtctag aaggttatgc
    52741 agctggtcca agtttggaag ctcgtacagg tgtacgtggg gaaactattg aactcaacaa
    52801 ccctgtttgg gatgttcaag cctactatat cgctcaagct gcggttaatg cgacagtgac
    52861 tttccgccca gacgtgattg tctttggtgg aggggtcatg gctcaacaac atatgctgga
    52921 ccgtgtccgt gagaaattta catctcttct taatggttac ctaccagtac cagatgtgcg
    52981 tgactatatc gtgacgccag cagtcgcagg aaatggttct gccacacttg ggaactttgt
    53041 tcttgcaaaa gaagtttcaa aataaagcac aaaatccgct tgggaaacca aacggatttt
    53101 gtggttgaaa acaatatttt tgagcctttc cttaagtgat tacggacggt agcgactttc
    53161 ttcgaaattc catacctaaa ctttgagcct agtgtctcaa agtttccgaa tacctgaaac
    53221 cattagattt caggtgtttc tatcacggcg gaaaggctag gtaagtcctc gcctcactat
    53281 cgaaaaatat gcatgatttc cataccaaag tatatttagt atcaagctat agttaatcta
    53341 cgctttaaaa atccacttgg gaaaccaaac ggatttttta cgtgtcaaag catttgccag
    53401 aaaaagtcaa taatataggt cagaccgtag gtataaacca cgagggtaaa gggtttggtc
    53461 agaatgatga tggtcatgta gcgcttgaaa ctcatcttgg tcagggcagc cagcatacag
    53521 agaaagtcag ctgggctaat gggccaaatc atcataaaaa taaagaagcg gtcaaaacga
    53581 ttgcccttat ctagccagcc gatgtacttg tcgtaggtgc gcttgctgac gacagactgg
    53641 acaaaggcag ctccgtatag gcgcactaga taaaagataa tggcacagcc aatcacgatg
    53701 ccgatatagt tgtagatagt cccgatgatg tgcccgtaga taaagacccc agccaccgag
    53761 gtcaaggccc ctggaatgat agggacgaca gtctgtaaaa tctgtaaaaa gataaagaga
    53821 ggtggacccc agatgcctgc ctgctggata aaggcagaga gggtttcctt ggattgtaaa
    53881 atcccagcct gataagccca aatacagaaa atcaaactcc caaccccacc gacaatcgat
    53941 gagatattga taactcgctg cagaagggga gaaacagctt tcatttgttt atcctgtgac
    54001 atgtaaactc ctcatagata gtatatttct actataccat attttggagg agaaaggggg
    54061 aatgagtctt ttttgataag gaatagaaag taaatagccc ttcgagactt agaataggtc
    54121 tgtcaactaa aggttatatg cattctaggt ttcgaataat cgcaattcca taaatttaaa
    54181 agcattctaa gtttcgaata gcttatctga gataattttg aggcattcgc gctttcgaat
    54241 agtcattttt cctaaagttt agatgtattc tgaagctaga aagactaaaa tctaaaagta
    54301 gtaagagtct ctctctgatg gacgtaattt atggctagta tgaatccttt gaattgttag
    54361 ttaattttaa tattaatcag ttctgaaata attactaaat atagttagat ggtgaattaa
    54421 ttattgctaa atttcaagtt caagttagtc atccagaagt cttctctggg ggacttgtag
    54481 ttcaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttcctttgta
    54541 gtcgttttct tagttccctg aggtaaccat ctatgaatga gtctgttgtg attttcatta
    54601 gatcctatag tgatgtgcat aatagatata gcagattgaa actagaatag tatacatcta
    54661 cttctaaaac attgttagaa atcaatttga ctgtcctgat caatttgtcc tgtttttatt
    54721 tcattttact atataatcct tagaaaacat atgggacaag cggttgaatt ctgttccgtc
    54781 cattagtaga taaaggatta ctccttcttg aaatgacaga tgaacttgtt tcttataaaa
    54841 atgttgtctg aaactattcg cctttttcca gaagttttag aggaagaaaa ctttatgagg
    54901 aaaaaggagt tactcaaata acaattcagg attaaaaata gacagttgag gagcggaagg
    54961 tataaattaa gtttgctact gtataatgga tttatcacta atactcttcg aaaatctctt
    55021 caaaccacgt cagcttcgcc ttgccgtacg tatagttact gacttcgtca gttctatcca
    55081 caacctcaaa acagtgtttt gagctgactt cgtcagtttt atctgcaacc tcaaagctgt
    55141 actttgagca gcctacggct agctttctag tttgctcttt gcttttcatt gagtataaaa
    55201 gtgctccagg ccatatttta cacagcaata gtcttctaaa aatggacaaa aaacattgta
    55261 aaggctatca aaaaggagta taatgagtgc aagaaatttc ggaggtgaaa gatgctagaa
    55321 gtaagaagtc tagagaaaag ttttggatcc aagcaagttt tgtttggtat tgactttcaa
    55381 gcgcgaccag gtcgtatttt gggactagtc ggaaaaaatg gtgctggaaa aacaacgatt
    55441 ttccatagta ttttgaaatt cctagaatat cagggagaaa tcggtctgga tggtcaggat
    55501 attcgtcagg agacctatgc tcggattggt tatctgcctg aagaacgcag tctcatgcct
    55561 aaattgacag ttcttgaaca agttcgctac ttggcgactc taaaaggcat ggatgccaaa
    55621 gaagtcaaag aaaaactccc tcaatggatg aagaggttgg aagtgaaagg aaagctgaca
    55681 gataaaatca agagtctgtc aaaaggaaat cagcagaaga ttcagctcat tattactctg
    55741 attcatgaac cagacctgat tatcttggat gagcctttta gtggattgga cccagttaat
    55801 acagaattgc tcaaacaagt catttttcag gaaaaagagc gcggagcaac cattatcttt
    55861 tctgaccatg tcatgaccaa tgttgaggaa ctttgtgacg atattctgat gatccgagat
    55921 ggccgtgtgg tcttgcacgg accagttcag gatgtccgca atcaatacgg gaaaacgcgt
    55981 ctctttgttt caagtgaacg aagcaaggaa gaattggaaa atcttcctca tgtcaaacag
    56041 gtgagcttga ccaaacaagg cagttggaaa ttgattttgg aggatgagag cgctggaagg
    56101 gaactcttcc caatcttgac tcaaggtcaa tatatcgcaa catttgacca acaagcgcca
    56161 actatcgatg aaatctttaa actagaatca ggagtggaag tatgagaaat atgtgggttg
    56221 taatcaagga aacctatctt cgacatgtcg agtcatggag tttcttcttt atggtgattt
    56281 cgccgttcct ctttttagga atctctgtag gaattgggca tctccaaggt tcttctatgg
    56341 ctaaaaataa taaagtggca gtagtgacaa cagtgccatc tgtagcagaa ggactgaaga
    56401 atgtaaatgg tgttaacttc gactataaag atgaagcaag tgccaaagaa gcaattaaag
    56461 aagaaaaatt aaaaggttat ttgaccattg atcaagaaga tagtgttcta aaggcagttt
    56521 atcatggcga aacatcgctt gaaaatggaa ttaaatttga ggttacaggt atactcaatg
    56581 aactgcaaaa tcagcttaat cgttcaactg cttccttgtc tcaagagcag gaaaaacgct
    56641 tagcgcagac aattcaattc acagaaaaga ttgatgaagt caaggaaaat aaaaagttta
    56701 ttcaaacaat tgcagcaggt gccttaggat tctttcttta tatgattctg attacctatg
    56761 cgggtgtaac agctcaggaa gttgccagtg aaaaaggcac caaaattatg gaagtcgttt
    56821 tttctagcat aagggcaagt cactatttct atgcgcggat gatggctctg tttctagtga
    56881 ttttaacgca tattgggatc tatgttgtag gtggtctggc tgccgttttg ctctttaaag
    56941 atttgccatt cttggctcag tctggtattt tggttcactt gggagatgct atctcactga
    57001 ataccttgct ctttattttg atcagtcttt tcatgtacgt agtcttggca gccttcctag
    57061 gatctatggt ttctcgtcct gaggactcag ggaaagcctt gtcgcctttg atgattttga
    57121 ttatgggtgg tttttttgga gtgacagctc taggtgcagc tggtgacaat ctcctcttga
    57181 agattggttc ttatattccc tttatttcga ccttctttat gccgtttcga acgattaatg
    57241 actatgcggg gggagcagaa gcatggattt cacttgctat tacagtgatt tttgcggtgg
    57301 tagcaacagg atttatcgga cgcatgtatg ctagtctcgt tcttcaaacg gatgatttag
    57361 ggatttggaa aacctttaaa cgtgccttat cttataaata gaagagcctt gcgaaagcga
    57421 ggtttttaaa ggtgaaaagg gtggaatcac gaacctaatt atgtacacat tatgtaaaca
    57481 ggttgcttga aaactcaatt gtatagtgaa ctgaatctgg aataggataa tattacttct
    57541 aaaacattct tataaattga tttgaattcc aaaatctcat cgttccgttc ttatttcatt
    57601 ttgcgatata gtgaaaggaa ataagtcagc tcacaaaaaa cgcataatat caaggatttt
    57661 taacacttga tactatgcgt tttctaattt taaagacttt ttgcctggtt tcttttgttc
    57721 tatgagtatg ttacatatct aggtaaaaat tatttaaagc aaattaacct tatttctcaa
    57781 gatgtagtag gttccgagat aaaagatagc tatgaatatg agttctttaa caatggctat
    57841 acctgctccc atatagaaat ggtcattgag tcctaccagt gaattgacat agaaattaga
    57901 actaagattg aagaaaagtt caataaatcc aatgacgatt tggataccaa tgtaggctgc
    57961 aacagcgagt gctgtacggt attcattgaa aagctgtcca atggaaatag ccaggtagat
    58021 gcagaggatt cctgaaatgg tatttagtag gaaggatata cctgtaagaa agatctgagg
    58081 gagatgtgtt tctacaaatg taatcacata agaaagagga atccattctg gagctgttaa
    58141 agccagaata ataacagcac ttagagccaa tacagcggtg ctaatcaatg accagataaa
    58201 ggcaccgatt agtttggctg tgatgatatg gtgttcagaa actggcaagg tcaaagtcag
    58261 atagccttgt cggtcgtaga cactaccttt gaagcgttta ataatcaaga aaatggttga
    58321 aatcgcaagt gtaagcatca agccaccaaa gactgtggct agaaaaagta gcatagtagc
    58381 ctgactttct tggtaaggta gatttttaaa gccttgtgtc tgtattccga tgagggcaga
    58441 aaggactagc acggctgcgt agagggctaa ataccacttg ttaacatttt taaattcgta
    58501 gcgaactaaa ttccaaaaca taaataatct cctttgctta ggccttaaat tcctgacgga
    58561 agagttggtc aatggattca cctgactcgt agcgaatatc atctacattt ccttgacgga
    58621 cgacttttcc gtcttttagg aagacaattt catccaagat tggctcgata tcagaaatca
    58681 agtgggtaga aatcaaaacg gtagaagttg gtgagtagtt gttgataatg gtattgagga
    58741 tataagcacg ggctgctgga tccaccccac caatgggttc gtccaaaaca tagagacgag
    58801 catcacggct cataaccaaa atcagttgaa ccttttcttt gtttcctttt gatagtttct
    58861 tgagacgact attttcatca atgcccaggt ctgcaagtag atgatgagcg cgttcaagat
    58921 tgaaatcttt atagaaggtc ttgaagtagg ttagggcttc tttgaccttc atttgctcat
    58981 tgagataggt cgtatcaggc aaataagcta caacggcctt ggttgctggg cttgggtcca
    59041 tgtcgttgat gaggacacgt ccttgatctg gttgtaagag gccattaatt agtttaatca
    59101 gggttgtttt tcctgagccg tttggcccaa gaaggccgac aatttttcca gctggaatgt
    59161 caagagaaac attttcaagg gctggtgttg ctccatatga tttggataca ttttcaaatg
    59221 ctagtaatga cataggctta aactccttta atataatcac tgactacgcc tggtagttct
    59281 tctttttcat agccaaaatg ggtcatggag gaaacgaagt gttccaattc ttcttctgat
    59341 aattgtttgc gtgactgagc gattagctcc ttatccttag tcacaaatcg tccagttgtt
    59401 cgcttgctgt agacaaatcc ttctcgttca aggtctgata aggctctttg gatggtattg
    59461 ggattgacac cagcctcgct agctagctcc ctcacggttg gaagttgttg attgggttcc
    59521 agtgtatggg aaacaatctg aagcttgatt ttctccataa tctgtaaata gatgggtttt
    59581 ttgttgtcaa atgtccagga catcttagtc tcctttctct tattcttttg tcttaattaa
    59641 ataatacaac aaaacaaaaa acttgtcaag caaaaagaag aattgttttg ggaatcgctt
    59701 aaaaaatggt ataatgaaaa gaaaacgata aggagggaaa ggatgcgttg tccaaaatgt
    59761 ggggctacca agtcaagtgt tatcgatagt cgccaagcag aagaagggaa caccattcgt
    59821 agaagacgag agtgcgacga gtgccaacac cgttttacaa cctacgaacg agtagaagaa
    59881 agaaccttag tggttgttaa aaaagatggc acacgggaac aattctccag agataaaatc
    59941 tttaatggga ttatccgctc agcccagaaa cgtcctgtgt caagtgatga aatcaacatg
    60001 gtagtcaatc gtatcgaaca gaaactccgt ggtcgaaatg aaaatgaaat tcaaagtgag
    60061 gacattggtt cactcgtcat ggaggagttg gctgaattgg acgagattac ctatgtacgt
    60121 tttgctagtg tctatcgtag ttttaaggat gtcagtgagt tagagagctt gctccaacaa
    60181 atcacccagt cctctaaaaa gaaaaaggaa agataaatga agccaattga ccgtttttct
    60241 tatctaaaga ataatcgggt gtcgcaagat acctcatctc tggtacagtg ctacctcccg
    60301 attatcggtc aggaggcact gagcctttat ctttatacaa tcagtttttg ggataatggt
    60361 agaaaggaat atcttttttc aagtatcctc aatcatctca actttgggat ggatagactg
    60421 ataaaatcat tgaaaatctt atctgctttt aatctcttga ccctctatca aaagggggat
    60481 gtttatcagc tagccctcca tgctcctcta tctagtcaag acttcttgga gcatcctgtt
    60541 tatcgcagac tcttagagaa aaagattggc gactctgctg tggaggattt gaaagttgaa
    60601 agtgctgatg gtgaagaaat acctgtctca ctcaatcaag tctttccaga attggcagaa
    60661 ctaggcagtc aagaagacct tggtctcaag aagaaagtgg ccaatgattt tgacttggat
    60721 cattttcgtc agctgatggc tcgagatgga cttcgttttg cggatgagca gtctgatgtc
    60781 ttgaacttgt ttgctattgc tgaggagaag aagtggactt ggtttgagac ctatcaattg
    60841 gccaagtcaa cagctgtttc ccaggttatt tcaaccaaac gcatgcggga aaaaattgct
    60901 caaaaaccag tttcctcgga ctttagtcct aaggaaacaa ccattatcaa ggaagctaaa
    60961 agtaaaactg ccttgcagtt cttggcagaa atcaagcaaa cacgcaaggg aaccactacc
    61021 caaacagaaa gagaactctt gcaacagatg gctggcttgg gcttgctgga cgaagtcatc
    61081 aatatcattc ttttattgac ctttaataag gtcgattcgg caaatatcaa tgagaaatat
    61141 gccatgaagg tagccaatga ctatgcctat caaaagattc attcggcaga agaggcagtc
    61201 ttgcgcatcc gtgagcgagg acagaaagca aaaacacaaa aacagaatca gactgcccca
    61261 gtaaaaacca atgttcctaa atggagtaat cctgaatata agaatgaaac cagcgaggaa
    61321 actcgtctgg aactagaacg taagaagcaa gaactattag ctcgattaga aaaaggagga
    61381 gattagatgg aaagtgtcgg agacgtactc aaacgtcaac ccagccgttt ttattatcaa
    61441 gatttggtcc agaaaatcat gaaggaccct gatgttgcgg cttttatcca gcaagaatcc
    61501 ttgactccag aggaattaaa tcgcagtatc tccaagttta atcagtacat caccgagcgt
    61561 gacaagtttc tccgtgggga tacggattat attgccaaag gctacaagcc gattttggtt
    61621 aagaatcatg gctatgcaga tgtttcatat gaagaaactc ctgagctaat cgcggctgaa
    61681 aaagaagcgg ctattaagaa ccgtctcaag ttaatcaatc taccagccag tctcaagaaa
    61741 gctagtttgg ctcaagttga cttggatgat ttggggcgct taccagtttt tgaaaagcta
    61801 ctagccttcg tggagcaata tccagctatt cgaaaaggtc tttacttgta tggagacttt
    61861 ggtgtgggta aaagtttcat ggtggctgcc ctagctcatg atttatcaga aaaacgtggt
    61921 gtatcatcca ctctcctcca ctatcctagc tttgtcattg atgtcaaaaa tgctattggt
    61981 gatggcaatg ttaagacctt agtggatgag attaagcttt ctgaagtcct gattttagat
    62041 gatattggtg ccgagcaatc caccgcttgg gtgcgtgatg aaatcctaca ggtcattctc
    62101 caatatcgga tgcaggaaaa tttaccgacc tttttcacct ctaacttcaa ctttgaagat
    62161 ttggagaagc atttcgctaa agggaaaaat ggaaatgacg aaacctggga agccagacgg
    62221 gtcatggaac gcatccgtta tttggctgag gagactcgtt tagaaggagt aaaccgtcga
    62281 tgacagaaac cattaaattg atgaaggctc atacttcagt gcgcaggttt aaagagcaag
    62341 aaattcccca agtagactta aatgagattt tgacagcagc ccagatggca tcatcttgga
    62401 agaatttcca atcctactct gtgattgtgg tacgaagtca agagaagaaa gatgccttgt
    62461 atgaattggt acctcaagaa gccattcgcc agtctgctgt tttccttctc tttgtcggag
    62521 atttgaaccg agcagaaaag ggagcccgac ttcataccga caccttccaa ccccaaggtg
    62581 tggaaggtct cttgattagt tcggtcgatg cagctcttgc tggacaaaac gccttgttgg
    62641 cagctgaaag cttgggctat ggtggtgtga ttatcggttt ggttcgatac aagtctgaag
    62701 aagtggcaga gctctttaac ctgcctgact acacctattc tgtctttggg atggcactgg
    62761 gtgtgccaaa tcaacatcat gatatgaaac cgagactgcc actagagaat gttgtctttg
    62821 aggaagaata ccaagaacag tcaactgagg caatccaagc ttatgaccgt gttcaggctg
    62881 actatgctgg ggcgcgtgcg accacaagct ggagtcagcg cctagcagaa cagtttggtc
    62941 aagctgaacc aagctcaact agaaaaaatc ttgaacagaa gaaattattg tagaaagtga
    63001 gaaattatgg ccctaccaac tattgccatt gtaggacgtc ccaatgttgg gaaatcaacc
    63061 ctatttaatc ggatcgctgg tgagcgaatc tccattgtag aagatgtcga aggagtgaca
    63121 cgtgaccgta tttatgcaac gggtgagtgg ctcaatcgtt cttttagcat gattgataca
    63181 ggaggaattg atgatgtcga tgctcctttc atggaacaaa tcaagcacca ggcagaaatt
    63241 gccatggaag aagcagatgt tatcgtcttt gtcgtgtccg gtaaggaagg aattaccgat
    63301 gcagacgaat acgtagcccg taagctttat aagacccaca aaccagttat cctcgcagtc
    63361 aacaaggtgg acaaccctga gatgagaaat gatatctatg atttctatgc tctcggtttg
    63421 ggtgaaccac tgcctatctc atctgtccat ggaatcggta caggggatgt actagatgct
    63481 atcgtagaaa atcttccaaa tgaatatgag gaagaaaatc cagatgtcat taagtttagc
    63541 ctgattggtc gtcctaacgt tggaaaatca agcttgatca atgctatctt gggcgaagac
    63601 cgtgttattg ccagtcctgt tgctggaaca actcgtgacg ctattgatac ccactttaca
    63661 gatacagatg gtcaagagtt taccatgatt gatacggctg gtatgcgtaa gtctggtaag
    63721 gtttatgaaa atactgagaa gtactctgtc atgcgtgcca tgcgtgctat tgaccgttca
    63781 gatgtggtct taatggtcat caatgcggaa gaggggattc gtgaatacga caagcgtatc
    63841 gctggatttg ctcatgaagc tggtaaaggg atgattatcg tggtcaacaa gtgggatacg
    63901 cttgaaaaag ataaccacac tatgaaaaac tgggaagaag atatccgtga gcagttccaa
    63961 tacctgcctt acgcaccgat tatctttgta tcagctttaa ccaagcaacg tctccacaaa
    64021 cttcctggga tgattaagca aatcagcgaa agtcaaaata cacgtattcc atcagctgtc
    64081 ttgaacgatg tcatcatgga tgccattgcc atcaacccaa caccgacaga caaaggaaaa
    64141 cgtctcaaga ttttctatgc gacccaagtg gcaaccaaac caccaacctt tgttatcttt
    64201 gtcaacgaag aagaactcat gcacttttct tacctacgtt tcttggaaaa tcaaatccgc
    64261 aaggcctttg tttttgaggg aacaccgatt catctcatcg caagaaaacg caaataaaaa
    64321 agtagaatct ggaatgacag ttccggattt ttttgatata ataaaataat agaaaacgct
    64381 atcaaaagaa ggagggggat gtcggtgatg gaacatttgt ttaaattctt acttttagca
    64441 ccgtactttt attttgataa ctggattgaa aaggccaaca gaaatagtaa gttttttcca
    64501 attttttatt atttttactg gatttacatc cccttctatt ctctttttag ccttgcttgg
    64561 acagttgttt cagttctgtt tttcaatacc gtcttgagaa atgtgacaga tatcaagtta
    64621 tggggcattt ggtttctttt tattctgcta gctattggta tgaattggtt aacttattcc
    64681 tgtttcaaag aaatgtttcg cttgagacag gaactaggga agtctaaggg tggaaggcat
    64741 tgatttatat cggtttctat ttgtaggagg tggcttatgg tacctctaaa atcatttatt
    64801 acacgctatt ccaaggttta tattggtaat aacatttaat agaacgaaac taaagaaaac
    64861 aatttaaaaa aggaggcttg tgatggaaca cttgtttaaa atgataatct tattaccctg
    64921 tttttacttt ttcagctgga ttgacaagga taatagagaa agtaaatttt tcccaatttt
    64981 ttactatttt tactggattt acatcaccct ctatgctctt tttagccttg cttggacagt
    65041 tttttcagtt ctgtttttca atatcgtctt gagaaatttg acagatatca agttatgggg
    65101 tatttggcta ttattactac ttatcgcttt tgctagtgac tggttagact atatctgttt
    65161 caaaaaaatg cttgacttga gacgggaact agggaagtct aaaggtgtgc ataaaggaag
    65221 gtgtaggaac taaaaaatga ctgtatctat gatttgttta tggagctata gatacagtca
    65281 tttttatttt gattatgaaa cttgagagaa atattcatct tgtatagtgg attgaatatg
    65341 gaataataca atacaactta taaaacattg gtataaaatg ctttagatcc cctaattgat
    65401 tcgttcacat tctattacaa tctactataa taaaatgatg agagttatta caaattatag
    65461 gtttgaaaaa tcattaattt ctttttcgat tatacaagga aacgattggt tgtcatttct
    65521 aaatttttta ctcaagattt gtttgtctgg tttcttggtt tacttccgct aggaattcat
    65581 ttcaaaacag tcgcactttt ctttttactt gctcagttaa tgatgttgta cttactactg
    65641 tcttatctga tagcactgat tagtgcgggc gctggttttt ctttttttct ctattttttg
    65701 gcatttgtgg gacaagaatg gatgatggat catattgtaa cagtgtattt agtactctta
    65761 agcttattag ttatgttgat tcttagtcgc ttggaagaga aatttaagaa aggataaacg
    65821 atgagacttg aaattataaa tggacagaaa atttatggga aaagacctat tttaaatcag
    65881 ttgaatttgg tgtttcaatc aggaaaaatt tatggactta aaggtgataa tggatctggc
    65941 aagacggttc ttttaaagat acttgctggt tatattaagc ttgacaaagg aaaagttctt
    66001 caagatggta aagtttacgg ggtaaaaaat cattatattc aggatgcagg aattttaatt
    66061 gaaaaagtcg agtttttatc tcatttatcc ctgagagaaa atttggaact gttaaggtat
    66121 ttttcatcta aagttacgga aaaaagaatt gcctattgga ttcaatacta tgatttacag
    66181 gaatttgaag atgttgaata ccgtcattta tccttgggaa caaagcaaaa aatggccttg
    66241 attcaagcct ttatttcctc tccttctata ctctttctcg atgaacctat gaatgctttg
    66301 gatgagaaaa gtgtgaggtt aaccaaacag gtcattttat cttacctgaa aaaagaaaat
    66361 ggtctggtta tcctgacgtc gcacatatcg gaagatattt cagacctttg tacagatgta
    66421 ttagttgtcg aaaatggaca tatacaatat gtaaaggata tacaatccta ggagatggct
    66481 tatggcacat ctaaaatcat ttattacacg ctattccaag gtttatattg gtttagttct
    66541 gctgatctgg ctgtctttct tctttatccc ttgggataga gcgattctgg gggtaaggat
    66601 tgacatcttc atcatacaga aagtcttgct agtttttgga attctgtcca ttttgatggc
    66661 cttgctgtcc aagaaagtca gtctctttgt ttttggactg atttgctgtc tttctctttg
    66721 gattaactta tttatcacat ttgccatttt gccgattttt ggcaattaaa cagtcataaa
    66781 agtcggagag gttagcttga aaactaacct ctttttcctt ttcaaaatgg ggattcttcc
    66841 ttgaaaataa tcagtaattg tgctaaaatt aaaggaacat tctaaaatat tcggaattta
    66901 aagtaaggaa aaacatggct aatattttaa aaacaattat cgaaaatgat aaaggagaaa
    66961 tccgtcgtct ggaaaagatg gctgacaagg ttttcaaata cgaagaccaa atggctgctt
    67021 tgactgacga ccaactaaaa gcaaaaacag ttgaatttaa ggaacgttat caaaatggag
    67081 aatcactgga ttcattgctt tacgaagcat ttgcggttgt ccgtgaaggt gccaaacgtg
    67141 tcctaggtct cttcccttat aaggttcagg tcatgggggg gattgttctt caccatggtg
    67201 acgtgccaga gatgcgtaca ggggaaggga aaaccttgac tgcgaccatg ccggtatacc
    67261 tcaatgccct ttcaggtaaa ggggttcacg tagttacggt taatgaatac ctgtcagaac
    67321 gtgacgcgac tgagatgggt gaattgtact cttggcttgg tttgtcagta gggattaact
    67381 tggctaccaa atctccaatg gagaaaaaag aagcctatga gtgtgatatt acttactcaa
    67441 ctaactcaga aatcggattt gactaccttc gtgacaacat ggtcgttcgc gctgaaaaca
    67501 tggtacaacg tccgcttaac tatgccttgg tcgatgaggt tgactctatc ttgattgacg
    67561 aggctcgtac acctttgatt gtatcaggtg ccaatgcggt tgaaaccagt cagttgtatc
    67621 acatggcaga ccactatgta aaatctttga acaaagatga ctacatcatc gatgtgcagt
    67681 ctaagactat tggtttgtct gattcaggga ttgacagggc tgaaagctac ttcaaacttg
    67741 aaaacctcta tgacatcgaa aacgtggctt tgacccactt tatcgataac gcccttcgtg
    67801 ccaactacat catgcttctc gatattgact atgtggtgag cgaagagcaa gaaatcttga
    67861 ttgtcgacca atttacaggt cgtaccatgg aaggtcgtcg ttattctgat ggattgcacc
    67921 aagctattga agccaaagaa ggtgtgccaa tccaggatga aaccaagaca tctgcctcaa
    67981 tcacgtacca aaaccttttc cgtatgtaca agaaattgtc tggtatgacg ggtacaggta
    68041 agactgagga agaagaattc cgtgaaatct acaacattcg tgttattcca atcccaacaa
    68101 accgtcctgt tcaacgtatt gaccactcag accttcttta tgcaagtata gaatctaagt
    68161 ttaaagcggt tgtcgaagac gttaaggctc gttaccaaaa gggtcaacct gtcttggttg
    68221 gtacagtagc ggttgaaact agtgactaca tttctaagaa attggttgca gctggtgttc
    68281 ctcacgaagt cttgaatgcc aaaaaccact atagagaagc ccaaatcatc atgaatgctg
    68341 gtcaacgtgg tgccgttacc atcgcaacca acatggcggg tcgtggtacc gacatcaagc
    68401 ttggtgaagg tgttcgtgaa cttggaggac tttgtgttat tggtacagaa cgtcatgaaa
    68461 gtcgtcgtat cgataaccag cttcgtggac gttcaggtcg tcaaggagat ccaggtgagt
    68521 cacaattcta cctatctctt gaagatgatt tgatgaaacg ttttggttct gaacgcttga
    68581 agggaatctt tgaacgcttg aacatgtctg aagaggcgat tgagtctcgc atgttgacgc
    68641 gtcaggttga agcagctcag aaacgtgtcg aaggaaataa ctacgatacc cgtaaacaag
    68701 tccttcaata cgatgatgtc atgcgtgaac aacgtgagat tatctatgct caacgttacg
    68761 atgtcatcac tgcagatcgt gacttggcac ctgaaattca gtctatgatt aagcgcacga
    68821 ttgaacgtgt cgttgatggt catgcgcgtg ccaaacaaga tgaaaaacta gaggcaattt
    68881 tgaactttgc taagtacaac ttgcttcctg aagattctat tacgatggaa gacttgtcag
    68941 gcttgtctga taaggccatc aaggaagagc ttttccaacg tgccttgaag gtttacgata
    69001 gtcaggtttc aaaactacgc gatgaagaag cagttaaaga attccaaaaa gttttgattc
    69061 tacgagtggt ggataacaag tggacagatc atatcgatgc ccttgatcaa ttgcgtaacg
    69121 cggttggact tcgtggctat gctcagaaca accctgttgt tgagtatcag gcagaaggtt
    69181 tccgtatgtt taatgatatg attggttcga ttgagtttga tgtgacacgc ttgatgatga
    69241 aagcacaaat tcatgaacaa gaaagaccac aggcagaacg tcatatcagt acaacagcga
    69301 ctcgcaatat cgctgctcac caagcaagta tgccagaaga tttggatttg agccagattg
    69361 gacgcaatga actttgccca tgtggttctg gtaagaaatt taaaaactgt cacggtaaaa
    69421 gacaataaaa tgagatagtt tagaggcgga tatcttgtga aaagtaaatt tttactgggt
    69481 atccgtttgc tttataagga gatgagttat ggtatttaca gcaaaaagct ctaaaataaa
    69541 tatagaagaa gttcgtgcct tgtcaaaatt agaaggtcag gctttggaga ggaaatcaca
    69601 gagagatcaa gagctagaag ccattatacg tggagaagac cagcgaattc tcttggtaat
    69661 cgggccatgc tcatctgata acgaagaagc tgtccttgaa tacgctaagc gtttggcagt
    69721 cctacaagaa gaagtggcag atcgtatctt tatggttatg cgtgtttata ctgccaaacc
    69781 ccgtaccaac ggagatggct ataaaggctt gattcaccag cctaacgcga cagaagcgcc
    69841 tagtcttatc aatggaatca aagccgttcg ccatcttcac tatcgtgtca tcacagaaac
    69901 agggatgaca actgctgatg aaatgcttta tcctgaaaac cttccgcttg tagatgattt
    69961 gatttcttac atggcagttg gtgcccgttc agttgaagac cagcaacacc gctttgtggc
    70021 aagtggggca ggattttcta ctggttttaa aaatccaacc tctggaaatc tcaatgtcat
    70081 gtttaatggg atttatgctg ctcaaaacaa acaaagtttc cttttcttag gaaaagaagt
    70141 agaaacaact gggaacccgc tttcacacgc tattcttcgt ggtgctctta atgagtatgg
    70201 aaaaaatatt cccaactact attatgacaa tttaattgat accattgccc agtatgagaa
    70261 aatgggcttg gaaaatcctt ttatcatcat tgataccaat catgacaatt ctggtaagca
    70321 gtatattgaa cagatccgaa ttgtccgcca gaccttgatt aaccgtgctt ggaatgaaaa
    70381 aattaagcag ttcgttcgtg gttttatgat tgagtcttat ctggaagatg gtcgacaaaa
    70441 tgagccagaa gtatttggta agtctatcac agacccttgc ctgggttggg ataacacaga
    70501 agctcttgtc agagaaattt acaaaacgtt aggagaataa gatggcattt attgaaaaag
    70561 gtcaagaaat cgatatggaa gtcatcaagg ctgaaaccca attgtctgca gaagccttga
    70621 gactcaagga aagccgtgac agggaattgg cagatattat ttcaggggaa gatgaccgta
    70681 ttctcttggt gattggtcct tgctcttctg ataatgaaga ggcggtcttg gaatatgctc
    70741 gccgtttatc cgccttgcaa aagaaggtag cggacaagat tttcatggtc atgcgcgtgt
    70801 atactgctaa gcctcgtacc aatggagacg gctataaagg attggttcac cagccagata
    70861 cttctaaggc tccaagcctg attaacggct tgcaggctgt gcgccagttg cactaccgcg
    70921 tgattacaga gactggtttg acaacggcag atgagatgct ttatccgtca aatctgatct
    70981 tggtggatga cttggtcagc taccatgccg ttggagctcg ttctgtggaa gaccaagagc
    71041 accgctttgt ggcttctggg attgatgcac cagtagggat gaaaaatcca acctcaggaa
    71101 atttgggtgt tatgtttaac gccatctatg ctgctcaaaa caagcaaacc ttcctttatc
    71161 atgggcagga agttgagaca tcaggtaatc ctttggccca tgttatcctc cgtggagcag
    71221 tcaacgagta tggcaattat atgccgaatt actactatga aaacctactc caagccattg
    71281 aacgctatga aaccatggga cttgaaaatc cttttatcct cattgacacc aaccatgata
    71341 actcaggcaa gcaatatatg gagcagattc gaattgttcg ccagaccttg cagaatcgtg
    71401 attggaatga gaaaattaaa aagacggttc gaggatttat gattgaatct tacctagcag
    71461 atggtcgtca aaaccaacca gagatctttg gttgctctat tactgaccct tgcctaggtt
    71521 gggaaaatac agaggccttg gtagaagaga tttatgttac cttgacaaaa taagtgaaaa
    71581 ggatggagtt ggggaatctc aactcctttt gatgagaatg atagttggac acggaattga
    71641 catcgaagaa ttggcttcga tagaaagcgc agttacacga catgaaggat ttgctaagcg
    71701 tgtactgacc gctcaggaaa tggagcgctt caccagtctc aaaggacgca ggcaaataga
    71761 atatttagct ggtcgctggt cggctaagga ggccttttcc aaggctatgg gaacgggcat
    71821 tagcaagctc ggttttcagg atttggaagt cttgaacaat gaacgtgggg cgccttattt
    71881 tagtcaggca ccattttcag gaaagatttg gctgtctatc agccacaccg atcagtttgt
    71941 gacagccagt gtcattttgg aggaaaatca tgaaagctag tccacataga ccaaccaagg
    72001 ctctgattca tctgggagct attcgacaaa atattcagca aatgggggct catatccctc
    72061 aaggaacgct caagttggct gtggtcaagg ccaatgctta tggtcatgga gctgttgccg
    72121 ttgccaaggc aattcaagat gatgttgatg gcttttgcgt ttccaatatc gatgaagcca
    72181 ttgaactcag acaagctgga ctcagcaagc caatcctcat tttaggagtt tctgaaatcg
    72241 aagctgttgc tctagctaaa gaatatgact tcaccttgac agtggctgga ctggagtgga
    72301 ttcaagcact cttagataag gaagtggacc taactggatt gacagtccac ctcaagattg
    72361 attcagggat gggacggatt ggttttagag aggccagtga ggttgagcag gctcaagatt
    72421 tgctccaaca acacggtgtt cgtgttgaag gaatctttac ccactttgct actgctgatg
    72481 aggaatcaga tgactatttt aatgcccagt tagaacggtt taaaactatt ttagctagta
    72541 tgaaggaagt tccagagctg gttcatgcta gcaattctgc aacgactctt tggcatgtag
    72601 agactatttt caatgcggtt cgtatgggag atgccatgta tggcctcaat ccaagtggag
    72661 cggtcttgga tttgccttat gatttgatac cggccttgac cttggagtct gctctggttc
    72721 atgtcaagac agttccagct ggagcttgca tgggctatgg agcaacttat caagcggata
    72781 gcgagcaagt catcgcgacc gtaccaatcg ggtatgcaga tggatggaca agagacatgc
    72841 aaaatttctc tgtcttggta gatggccaag cttgcccaat tgtcggcagg gtttcgatgg
    72901 accaaatcac tattcgattg cctaagcctt acccactcgg aaccaaggta accttgattg
    72961 gctccaatgg ggataaggaa atcactgcaa ctcaggtagc gacctaccgc gtaaccatta
    73021 actatgaggt ggtttgcctc ctcagcgacc gtattccgag agaatattat tagaaaagaa
    73081 aggagtggag catgaatcta catcaaccct tgcatgtctt gcctggtgtg ggaccaaagt
    73141 cagcagaaaa atatgccaaa ctaggaattg aaaacttgca agatctcttg ctctactttc
    73201 ctttccgtta tgaagacttc aaaaccaagc aggtgctgga gctggaagac ggtgagaagg
    73261 cagttctttc tggtcaggta gtgactcctg ctagtgtcca gtattatggt ttcaagcgca
    73321 atcgcctgcg ttttagtctc aagcagggag aggtcgtttt tgcggtgaat ttctttaacc
    73381 agccctatct ggctgataaa atagagttgg gagcaaccct tgctgtcttt ggaaaatggg
    73441 accgcgctaa ggctagtctg aatgggatga aggttctggc tcaggtagaa gatgacctcc
    73501 agcctgttta tcgtctggct cagggaatca gtcaggccag tctggttaag gtcatcaaga
    73561 cggcttttga tcagggactg gacctcttga tagaagaaaa tctgccccag tctttactag
    73621 acaaatacaa actcatgtcc cgttgtcagg cagtccgagc tatgcatttt ccaaaggatt
    73681 tggcagaata caagcaggct cttcgccgta taaagtttga ggaactcttt tatttccaaa
    73741 tgcagctgca gatgctcaag tctgaaaata gagttcaggg aagtggtctg gttctggatt
    73801 ggtctcagga aaaagtgaca gcagttaaag caagtcttcc ttttgccctg acccaagctc
    73861 aggaaaagag tttgcaggaa attttaactg atatgaagtc cgaccaccac atgaatcgtc
    73921 tcctacaagg ggatgtgggg agtggaaaaa cggtagtcgc tggcttggcc atgtttgcgg
    73981 cagtgacagc aggttatcag gctgccctaa tggtaccaac agaaatcctc gcagagcaac
    74041 actttgagag tttacagaac ctttttccca atttgaaact ggctctcttg acaggttcct
    74101 tgaaagctgc agaaaagaga gaagtcttgg agaccattgc caagggtgag gctgatttga
    74161 ttataggaac tcacgctctg atacaagatg gggtggagta tgctcgtctt ggtttgatta
    74221 ttatcgatga gcagcaccgt tttggtgtag ggcaaaggcg tattttacgg gaaaaaggtg
    74281 acaatccaga tgtcctcatg atgacggcga ctcccattcc acggacgctt gccatcacag
    74341 cctttggaga tatggatgtt tccattatcg accagatgcc agcaggtcgg aagcctattg
    74401 tgacgcgctg gatcaaacat gagcaactac ctcaggtctt gacttggtta gagggggaaa
    74461 ttcaaaaagg ttcccaagcc tatgtcatct ctcctttgat tgaagaatca gaagctctag
    74521 atttgaaaaa tgccattgcc ttatcagagg agttgacgac tcattttgca ggcaaggcag
    74581 aggtggctct tctacatggt aggatgaaga gtgacgaaaa agaccagatc atgcaggatt
    74641 tcaaggagag aaagacggat attctggttt cgacgacggt tattgaggtt ggggtcaacg
    74701 ttcccaatgc gactgtcatg attatcatgg atgccgatcg cttcggtctc agtcaacttc
    74761 accagcttag aggtcgtgtc ggtcgggggg acaagcagtc ctacgctgtt ctcgttgcca
    74821 atcccaagac ggattctggg aaagaccgca tgcgcatcat gacagaaacg accaatggat
    74881 ttgtccttgc ggaggaagat ttgaaaatgc gtggttctgg tgagattttt ggaaccagac
    74941 agtcaggact tccagagttc caagtggctg atattatcga agattttccg attttagaag
    75001 aagcaagaaa ggttgctagc tacattagtt ctatagaagc ttggcaagaa gatccagagt
    75061 ggcgcatgat tgcccttcat ctggaaaaga aagaacatct ggattaagct ttctctaagg
    75121 aaaacttata ctcaatgaaa atcaaagagc aaactaggaa gctaaccg
//
LOCUS       DAVLMQ010000005        68544 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000005 DAVLMQ010000000
VERSION     DAVLMQ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68544
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.005"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(660..882)
                     /locus_tag="VXF95_000413"
                     /pseudo
     CDS             complement(660..882)
                     /locus_tag="VXF95_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838792.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(1040..1294)
                     /locus_tag="VXF95_000414"
     CDS             complement(1040..1294)
                     /locus_tag="VXF95_000414"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1081007.1"
                     /translation="MGTKIGISKNTIGNYEKRVRSTKKNTIFDLVKVFSSLIDALFSP
                     VQKDSPSDIQSIYDQRAPPRQGKVLTYAERQLYDQKNEVS"
     gene            1730..2602
                     /locus_tag="VXF95_000415"
     CDS             1730..2602
                     /locus_tag="VXF95_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HEV1081008.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLDTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2751..3092)
                     /locus_tag="VXF95_000416"
                     /pseudo
     CDS             complement(2751..3092)
                     /locus_tag="VXF95_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3235..3546
                     /locus_tag="VXF95_000417"
     CDS             3235..3546
                     /locus_tag="VXF95_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081009.1"
                     /translation="MELKDFTEKEQEMIKKRLTMSNISDKETTEKILALVPQDLIKRI
                     PFFVRKHATTRTIKRISIEHPELYAVAQTSGEIPEKEREELRQIITTIFEQKMNKHSI
                     K"
     gene            3550..4248
                     /locus_tag="VXF95_000418"
     CDS             3550..4248
                     /locus_tag="VXF95_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1081010.1"
                     /translation="MKKYFIGGLGNNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSLGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIVSDLALLISKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNGATWREEALLDTIFLENFGHELYTQAPK
                     EIASLMNEWLAYFL"
     gene            complement(4377..5192)
                     /locus_tag="VXF95_000419"
     CDS             complement(4377..5192)
                     /locus_tag="VXF95_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HEV1081011.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWITAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5189..6094)
                     /locus_tag="VXF95_000420"
     CDS             complement(5189..6094)
                     /locus_tag="VXF95_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HEV1081012.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGILFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKGFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMLLAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLAYSLLIGVIL"
     gene            complement(6424..6507)
                     /locus_tag="VXF95_000421"
                     /pseudo
     CDS             complement(6424..6507)
                     /locus_tag="VXF95_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            6551..8680
                     /locus_tag="VXF95_000422"
     CDS             6551..8680
                     /locus_tag="VXF95_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HEV1081013.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNVYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
     gene            8667..9116
                     /locus_tag="VXF95_000423"
     CDS             8667..9116
                     /locus_tag="VXF95_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HEV1081014.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTKRYRCGLCRGKLLLINQPED"
     gene            9175..9447
                     /locus_tag="VXF95_000424"
     CDS             9175..9447
                     /locus_tag="VXF95_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1081015.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(9801..9992)
                     /locus_tag="VXF95_000425"
     CDS             complement(9801..9992)
                     /locus_tag="VXF95_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081016.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNILSQQQK"
     gene            10420..11178
                     /locus_tag="VXF95_000426"
     CDS             10420..11178
                     /locus_tag="VXF95_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081017.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVVTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFDEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            11180..13168
                     /locus_tag="VXF95_000427"
     CDS             11180..13168
                     /locus_tag="VXF95_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081018.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTVTYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVVFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQTKVVITVLV
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSSESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVFRYTYFAVANQEGTELTIFEKGQNRVQPKTIFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNEGVKEQKTLILNDHQFSVKEEFNKDFIVKHVPNQF
                     NILTADYNYLVVPDLQAFLNQFPDSAIYNQFYGGMNVNVSEEEQLKVAEEYEKYLQKF
                     NAQLNTEGNYVYGSTLADASAQMSVLFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFLHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(13210..13854)
                     /locus_tag="VXF95_000428"
     CDS             complement(13210..13854)
                     /locus_tag="VXF95_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HEV1081019.1"
                     /translation="MLRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAG
                     AFSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLYAAYIQNGECKTSAQLL
                     TNKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYR
                     IPATVLIVGVALLLTGYTSARLGKAPTKTAMIRNLAIGLLTMGVTFLLGQLFSI"
     gene            complement(13826..14875)
                     /locus_tag="VXF95_000429"
                     /pseudo
     CDS             complement(13826..14875)
                     /locus_tag="VXF95_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001153810.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            15582..17057
                     /locus_tag="VXF95_000430"
     CDS             15582..17057
                     /locus_tag="VXF95_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HEV1081020.1"
                     /translation="MKELDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
     gene            complement(17023..17738)
                     /locus_tag="VXF95_000431"
                     /pseudo
     CDS             complement(17023..17738)
                     /locus_tag="VXF95_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            17994..18854
                     /gene="speE"
                     /locus_tag="VXF95_000432"
     CDS             17994..18854
                     /gene="speE"
                     /locus_tag="VXF95_000432"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HEV1081021.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            18851..20110
                     /locus_tag="VXF95_000433"
     CDS             18851..20110
                     /locus_tag="VXF95_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HEV1081022.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            20110..21237
                     /gene="nspC"
                     /locus_tag="VXF95_000434"
     CDS             20110..21237
                     /gene="nspC"
                     /locus_tag="VXF95_000434"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HEV1081023.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEVGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLGITDHIVF
                     NSERQLRKHGARCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGADDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPPLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            21234..22319
                     /gene="aguA"
                     /locus_tag="VXF95_000435"
     CDS             21234..22319
                     /gene="aguA"
                     /locus_tag="VXF95_000435"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HEV1081024.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKDAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALERPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAEVVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEERYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            22329..23204
                     /gene="aguB"
                     /locus_tag="VXF95_000436"
     CDS             22329..23204
                     /gene="aguB"
                     /locus_tag="VXF95_000436"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HEV1081025.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(23384..24193)
                     /locus_tag="VXF95_000437"
     CDS             complement(23384..24193)
                     /locus_tag="VXF95_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1081026.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKFRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            24465..24686
                     /locus_tag="VXF95_000438"
     CDS             24465..24686
                     /locus_tag="VXF95_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081027.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKEPNGYYPWQMEPVLTMP
                     VHGFCPRGTDDLVYIVGGNHLCKGSAARF"
     gene            24740..25411
                     /locus_tag="VXF95_000439"
     CDS             24740..25411
                     /locus_tag="VXF95_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1081028.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRLFNYLAKPYLPASREFFQIL
                     LLLESGVLLSAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISPPS
                     NQISLNETIEMMGRQEFPYFLLIVCFIAPIAEELIYRGVIMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(25463..25660)
                     /locus_tag="VXF95_000440"
     CDS             complement(25463..25660)
                     /locus_tag="VXF95_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1081029.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            25653..26561
                     /locus_tag="VXF95_000441"
     CDS             25653..26561
                     /locus_tag="VXF95_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1081030.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            26558..27019
                     /locus_tag="VXF95_000442"
     CDS             26558..27019
                     /locus_tag="VXF95_000442"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HEV1081031.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRVSQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            27009..27896
                     /locus_tag="VXF95_000443"
     CDS             27009..27896
                     /locus_tag="VXF95_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1081032.1"
                     /translation="MEIKIETGGLRLDKALSDLSELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVTAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIGHSVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            27899..29794
                     /gene="cbpE"
                     /locus_tag="VXF95_000444"
                     /gene_synonym="pce"
     CDS             27899..29794
                     /gene="cbpE"
                     /locus_tag="VXF95_000444"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HEV1081033.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     AAEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHLDTKNSNTKNFIKNLSPEIIVQ
                     TSSSPIGSYDSGQEINREYISWLESMGIQHINAASKDYDATVFDIRQDGLINISTSYK
                     PIPSFQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNN
                     RWFYLTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQY
                     KGQWYYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWH
                     KKANDWYFYKTDGSRAVGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVS
                     IEKSATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSV
                     NKSESEQ"
     gene            29874..31004
                     /locus_tag="VXF95_000445"
     CDS             29874..31004
                     /locus_tag="VXF95_000445"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HEV1081034.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDEVKVGDNDTLSA
                     QVAAMVQADLLVLLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDILRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            31014..32276
                     /locus_tag="VXF95_000446"
     CDS             31014..32276
                     /locus_tag="VXF95_000446"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HEV1081035.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSHESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHEDKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVA
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            32280..33077
                     /gene="proC"
                     /locus_tag="VXF95_000447"
     CDS             32280..33077
                     /gene="proC"
                     /locus_tag="VXF95_000447"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HEV1081036.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLILEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLSKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMEAVHQAYKRTQELGK"
     gene            33297..33935
                     /locus_tag="VXF95_000448"
     CDS             33297..33935
                     /locus_tag="VXF95_000448"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HEV1081037.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEVKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLEKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            33932..34822
                     /locus_tag="VXF95_000449"
     CDS             33932..34822
                     /locus_tag="VXF95_000449"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HEV1081038.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEMAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQEEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            34862..35179
                     /gene="yabA"
                     /locus_tag="VXF95_000450"
     CDS             34862..35179
                     /gene="yabA"
                     /locus_tag="VXF95_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HEV1081039.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            35182..36060
                     /gene="rsmI"
                     /locus_tag="VXF95_000451"
     CDS             35182..36060
                     /gene="rsmI"
                     /locus_tag="VXF95_000451"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HEV1081040.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESPHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     SETSLKGECLLIVEGASKGVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEENQEND"
     gene            36195..37529
                     /gene="trmFO"
                     /locus_tag="VXF95_000452"
     CDS             36195..37529
                     /gene="trmFO"
                     /locus_tag="VXF95_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HEV1081041.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVANHPLIEVVRDEITELPTDVITVIATGPLTSDALAEKIHALNDGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
     gene            37613..38350
                     /locus_tag="VXF95_000453"
     CDS             37613..38350
                     /locus_tag="VXF95_000453"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HEV1081042.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            38359..38916
                     /gene="frr"
                     /locus_tag="VXF95_000454"
     CDS             38359..38916
                     /gene="frr"
                     /locus_tag="VXF95_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HEV1081043.1"
                     /translation="MANVIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVI
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            38976..39830
                     /gene="cvfB"
                     /locus_tag="VXF95_000455"
     CDS             38976..39830
                     /gene="cvfB"
                     /locus_tag="VXF95_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HEV1081044.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTTLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            39839..40054
                     /locus_tag="VXF95_000456"
     CDS             39839..40054
                     /locus_tag="VXF95_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HEV1081045.1"
                     /translation="MRKSFYTWLMTERNPKSNSPKAILADLAFEESAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            40140..41144
                     /locus_tag="VXF95_000457"
     CDS             40140..41144
                     /locus_tag="VXF95_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HEV1081046.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMVLVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQEKLKNIYQIDFVHFSAKDVVRHPVVAQIIRAYEPAPVKKEESEELESQPLSEG
                     "
     gene            41252..41821
                     /locus_tag="VXF95_000458"
     CDS             41252..41821
                     /locus_tag="VXF95_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081047.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKSNGQFIGTIDLHKIDSVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKDNPASGKVMEKSGMRFSHAEP
                     YACMDQHEKDRIVTRVHYVLTKEDYFANK"
     gene            41889..42539
                     /locus_tag="VXF95_000459"
     CDS             41889..42539
                     /locus_tag="VXF95_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEA family DNA-binding protein"
                     /protein_id="HEV1081048.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQ
                     AEVAAVSKDLVSEKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSISKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD"
     gene            42523..44763
                     /locus_tag="VXF95_000460"
     CDS             42523..44763
                     /locus_tag="VXF95_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HEV1081049.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCL
                     FIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQNLADSVERVRILPDTIKVNGDSL
                     SFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
                     LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     TFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLI
                     SLALVYDLRKNIKKLTVLCLLITGLFLLIKHPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGLDSW
                     KIESVR"
     gene            44942..45130
                     /locus_tag="VXF95_000461"
     CDS             44942..45130
                     /locus_tag="VXF95_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081050.1"
                     /translation="MTATKSYKYDWNTVLEYSTNYHDHQYAWIPEWSRYYSYSEYKVG
                     GGWNYARYEVINYYTGGY"
     gene            45162..45749
                     /locus_tag="VXF95_000462"
     CDS             45162..45749
                     /locus_tag="VXF95_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081051.1"
                     /translation="MLNLTHVTLKTRQVILQDADFTFKKGRIYGLLAINGSGKTTLFR
                     AMSKLLPLSSGHIAVPPSLFYYESVEWLDGNLSGMDYLRLIKNIWKSDLNLRDEIAYW
                     EMADYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDICDRVVTIHQGQIEEV"
     gene            45753..46934
                     /locus_tag="VXF95_000463"
     CDS             45753..46934
                     /locus_tag="VXF95_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081052.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLPKQIDNVNLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFK
                     V"
     misc_feature    47094..47225
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            47241..47771
                     /gene="infC"
                     /locus_tag="VXF95_000464"
     CDS             47241..47771
                     /gene="infC"
                     /locus_tag="VXF95_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HEV1081053.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     gene            47804..48004
                     /gene="rpmI"
                     /locus_tag="VXF95_000465"
     CDS             47804..48004
                     /gene="rpmI"
                     /locus_tag="VXF95_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HEV1081054.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            48056..48415
                     /gene="rplT"
                     /locus_tag="VXF95_000466"
     CDS             48056..48415
                     /gene="rplT"
                     /locus_tag="VXF95_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HEV1081055.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            48473..48853
                     /locus_tag="VXF95_000467"
     CDS             48473..48853
                     /locus_tag="VXF95_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1081056.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            49103..49903
                     /locus_tag="VXF95_000468"
     CDS             49103..49903
                     /locus_tag="VXF95_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HEV1081057.1"
                     /translation="MNLTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            49866..50852
                     /locus_tag="VXF95_000469"
     CDS             49866..50852
                     /locus_tag="VXF95_000469"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HEV1081058.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            50894..53059
                     /gene="lytB"
                     /locus_tag="VXF95_000470"
     CDS             50894..53059
                     /gene="lytB"
                     /locus_tag="VXF95_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HEV1081059.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWIFDTHYQSWFYIKADANYAENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWIYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQAWYYFKSGGYMAANEWIWDKESWFYLKFDGKMAEKEWVYDSHSQAWYYFKSGGYM
                     TANEWIWDKESWFYLKSDGKIAEKEWVYDSHSQAWYYFKSGGYMTANEWIWDKESWFY
                     LKSDGKMAEKEWVYDSHSQAWYYFKSGGYMAKNETVDGYQLGSDGKWLGGKATNKNAA
                     YYQVVPVTANVYDSDGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQ
                     ALDASKDFIPYYESDGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLYFDGFKLE
                     NPFLFKDLTEDTNYSAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHS
                     ALESNWGRSKIAKDKNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGR
                     TFLGNKASGMNVEYASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(53120..54775)
                     /gene="pavA"
                     /locus_tag="VXF95_000471"
     CDS             complement(53120..54775)
                     /gene="pavA"
                     /locus_tag="VXF95_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HEV1081060.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTESLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPFANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            54880..55377
                     /gene="ybeY"
                     /locus_tag="VXF95_000472"
     CDS             54880..55377
                     /gene="ybeY"
                     /locus_tag="VXF95_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HEV1081061.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            55358..55753
                     /locus_tag="VXF95_000473"
     CDS             55358..55753
                     /locus_tag="VXF95_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HEV1081062.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFAITGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            55770..56669
                     /gene="era"
                     /locus_tag="VXF95_000474"
     CDS             55770..56669
                     /gene="era"
                     /locus_tag="VXF95_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HEV1081063.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEKEY"
     gene            56717..57541
                     /gene="mutM"
                     /locus_tag="VXF95_000475"
     CDS             56717..57541
                     /gene="mutM"
                     /locus_tag="VXF95_000475"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HEV1081064.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYPKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFYLTDKVLISHLRMEGKYFYYPDQGPERKHAHVFFHFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQSALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARSSQTLTAEEATAIHDQTIAVLSQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            57541..58146
                     /locus_tag="VXF95_000476"
     CDS             57541..58146
                     /locus_tag="VXF95_000476"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HEV1081065.1"
                     /translation="MRKIIGITGGIASGKSTVTNFLRQQGFQVVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSKQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            58133..59332
                     /locus_tag="VXF95_000477"
     CDS             58133..59332
                     /locus_tag="VXF95_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HEV1081066.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSIMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            59332..59481
                     /gene="rpmG"
                     /locus_tag="VXF95_000478"
     CDS             59332..59481
                     /gene="rpmG"
                     /locus_tag="VXF95_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1081067.1"
                     /translation="MRVKINLKCSSCDSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            59521..59754
                     /gene="secG"
                     /locus_tag="VXF95_000479"
     CDS             59521..59754
                     /gene="secG"
                     /locus_tag="VXF95_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HEV1081068.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            59856..62210
                     /gene="rnr"
                     /locus_tag="VXF95_000480"
     CDS             59856..62210
                     /gene="rnr"
                     /locus_tag="VXF95_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HEV1081069.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLTLEAKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     DGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERIIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLCIYGTASEISQE
                     ALQDIMRAVEGEPYADVLSMMLLRSMQQARYSEHNHGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGCSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKL
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            62173..62640
                     /gene="smpB"
                     /locus_tag="VXF95_000481"
     CDS             62173..62640
                     /gene="smpB"
                     /locus_tag="VXF95_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HEV1081070.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKKQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            62656..63516
                     /gene="tehB"
                     /locus_tag="VXF95_000482"
     CDS             62656..63516
                     /gene="tehB"
                     /locus_tag="VXF95_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HEV1081071.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMQTVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIGQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            63589..64542
                     /gene="coiA"
                     /locus_tag="VXF95_000483"
     CDS             63589..64542
                     /gene="coiA"
                     /locus_tag="VXF95_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HEV1081072.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQYFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            64561..66363
                     /gene="pepF"
                     /locus_tag="VXF95_000484"
     CDS             64561..66363
                     /gene="pepF"
                     /locus_tag="VXF95_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HEV1081073.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQMEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYDPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYNFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKIGLA"
     gene            66365..67078
                     /locus_tag="VXF95_000485"
     CDS             66365..67078
                     /locus_tag="VXF95_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HEV1081074.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGSLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            67145..68086
                     /gene="prsA"
                     /locus_tag="VXF95_000486"
     CDS             67145..68086
                     /gene="prsA"
                     /locus_tag="VXF95_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HEV1081075.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDVITEHQFY
                     EQVKSNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(68205..>68544)
                     /locus_tag="VXF95_000487"
     CDS             complement(68205..>68544)
                     /locus_tag="VXF95_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HEV1081076.1"
                     /translation="VGTAFKEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRK
                     GNSQDNGRMESFFGILKSEMFYGYEQTFKSLNQLEQAIIDYIDYYNNKRIKIKLKGLS
                     SVQYRTKSFG"
BASE COUNT        20518 a        12684 c        15281 g        20061 t
ORIGIN      
        1 gacttttttt ctacacaaaa ataggctcca taatatccat aggggggtta cccactacaa
       61 atattataga gcctcataat ggattgatac tcttcgaaaa tcaaattcaa accacgtcag
      121 cgtcgcctta ccgtactcaa gtacagcttg cggctagctt cctagtttgc tctttgattt
      181 tcattgagta tgaaataaga tatgcacaaa ttgattagaa agtcaaatga atttctacaa
      241 atgttttagc aatcgtaatg tacttgtcta gattcgatct gatatatttt cgatttaatg
      301 atatggtatt taaaaccttc aaagtagctt gctccattct tttacttacg tgagtgtaga
      361 tgttatttac tgttttagcg tttttgtgtt ccactctaac cattatagca ttcttctcag
      421 ctagtgtact aaggagtgtg tgcctgaaaa tatgggaact aaggggctgg tttatcggtt
      481 tctctagttt agtatttgcc ttttgcaaag tgatgttaaa tgcctttctc taaatttaca
      541 tatcactatt gtttaacaaa atctaatcta ttttaggtca cttattcttt ttttgaaatg
      601 tagaatgaac tttttcaaag tttttcgaat cttttaaaat ctgtttgttt tatatcgcca
      661 ttctccctat atagcctgac aactttcccg atggtacgaa tatggttgct ttcgtctagg
      721 tggatgtcgg ggtatttggg attgagtttt tttaaggtag ccttggcgga gtttcttgac
      781 atagttagcg ccgtctactt ggaagatgcc gatggtatta tagtcaatct gtggggtatt
      841 cttgataaat aggtagtcgc tgtttcttat ctttggctcc atggacttgc tgacgacata
      901 agcgattggg tcgtagtcgt ctgggataat ggaaactcca tatctaaatc gttgtcctgc
      961 atcgagcggc tacctgcaga gataaactac ctaacacgag agtaagtagt ctgtctgtag
     1021 tcgtccagtc tgatgatttt tacgatactt cgtttttctg atcatacagt tgcctctcgg
     1081 cataggtcag aactttacct tgtctgggtg gtgcccgttg gtcgtagata gattggatat
     1141 cgctaggaga atccttttga actggagaaa agagggcatc aatcaagcta ctgaatactt
     1201 taactaagtc aaatatagta tttttcttag tagacctaac ccttttttca taatttccaa
     1261 tggtgttttt acttatacca atcttagtac ccaattctta ttgagtccaa ccattactag
     1321 tctatattgt tttatagttg attgagtttg gaatagtacg ctgtagctgc taaaacattt
     1381 ctaggaatta atttgccttt cctaatagag ttgttcatat cttatttcaa tctactatat
     1441 ttttcgcctc taacaatcgc aatctcttct ttatctacga atgaaatcgc tttctatttt
     1501 tgtaagtaaa gcatcacacg aaatccacga aaatgaaaac ctttgttgtg ttttcgtaaa
     1561 aaatttgttg acagagcacg aaacgcctac tataattaaa tcaagcttaa ggaaataaca
     1621 aaaaaacaaa tcggagggaa agacgatgaa cacattaaat gagaaagtaa tcaatatctg
     1681 taaagcagta gttaaagaaa ctttaatcca agacatttag gagaaagaaa tgaagaaatc
     1741 aagaaaatta gccacattag gaatctgttc agctttgttt ttaggcttgg ctgcttgtca
     1801 acaacaacat gctacttctg aggggacgaa tcaaaggcaa agcagttcag cgaaagttcc
     1861 atggaaagct tcatacacca acctaaacaa ccaggtaagt acagaagagg tcaaatctct
     1921 cttatcagct cacttggatc caaatagtgt tgatgcattt tttaatctcg ttaatgacta
     1981 taataccatt gtcggctcaa ctggcttatc aggagatttc acttccttta ctcacaccga
     2041 atacgatgtt gagaaaatca gtcatctctg gaatcaaaag aagggcgatt ttgttgggac
     2101 caactgccgt atcaatagtt attgtctttt gaaaaattca gtcaccattc caaagcttga
     2161 aaagaatgac cagttgcttt tcctagataa tgatgcgatt gataaaggaa aggtctttga
     2221 ttcacaagat aaggaagagt ttgatattct attttcgaga gttccaactg aggcaactac
     2281 agatgtcaag gttcacgctg aaaagatgga aacattcttc tcacaatttc aattcaatga
     2341 aaaagctcga atgctgtctg tagtcttgca cgacaatctg gatggcgagt atctgtttgt
     2401 aggccacgtt ggggtcttag tacctgctga tgacggtttc ttatttgtag agaaattgac
     2461 tttcgaagag ccctaccaag cgattaaatt tgctagtaag gaagattgct acaagtattt
     2521 ggacaccaag tatgcggatt atacaggcga gggactggct aagcctttta tcatggataa
     2581 tgataagtgg gttaaacttt aatagtgtta tgatatgaca gtaatcttag gatttttatt
     2641 tctatttttg atgagttggt gggttatttc aatcgttaat agccagaaac cacgcaaaaa
     2701 tgaaacattt attggctatg tccaaagata cgatattgat gggaatggct atcaatcatt
     2761 accgtgtcct cagaactgag aggagttctt gaaatcgtaa aaccactttg aacaagagtt
     2821 acttcaaccc attggctccg acggattaag ttgctttcgt gaataccaaa atcagccgca
     2881 atttcttcat aagtgcggta ttctcgcaca tattgaagag tggccataag aaggtcttct
     2941 aggcttaatt taggttttcg tccacctttt gcgtgtttaa gttgataagc tgtttttaat
     3001 acagctaaca tctcttcaaa agtcgtgcgc tgaacaccaa caagacgctt aaatcgtgca
     3061 tcagttagtt gtttacttgc ttcataattc atagaactat tataccatgt tttgtttcgc
     3121 aggaaatcta atgctaaaat cttatcagtg agaagatttc ttaaagttta ttctttgtag
     3181 tttcatctgt attagtacat aatttaactt agagaaaata ggaggactaa tcgaatggaa
     3241 ttaaaagatt ttacagaaaa agaacaggaa atgattaaga aaaggcttac aatgtctaat
     3301 attagtgaca aagaaactac tgagaagatt ctggcgctag taccacaaga cttgattaag
     3361 cgaatcccgt tttttgtcag aaaacatgct acaacacgta cgattaaacg catttcaatt
     3421 gaacaccctg aactctacgc tgtagctcaa acaagtggtg agattccaga aaaagaacgc
     3481 gaagaattgc gtcagattat cacaactatc tttgaacaaa agatgaataa gcatagtatt
     3541 aagtagagaa tgaaaaaata ttttattggc ggtttgggaa ataatgccta tcatagcaag
     3601 gattttcttc aagaactaga ttcgcaggtc tattttctaa atccatatga aaagcatctt
     3661 cgagatgaaa cagaattgaa atcatggttt aaaaatgaga ttgtagagga agaatctatc
     3721 tgtctgatag gccattctct tggaggagat ttagctcgtt atttcgcatc ggaatttgaa
     3781 gaagtaaaga aactgattct tttggatggt ggctatctag atttagataa gattttacct
     3841 ttggatacag agttagagga aactaaaaat tatatcaaat ctcaaattgt ttcggactta
     3901 gctcttctta tttctaaaga gaagtccgaa gcaaagcatt ggtcagaaaa tatggagaaa
     3961 gctgtaagac agtcctatca ctggaatgtt gagtataata gatatgagtt ggctataaat
     4021 tatgaaaata tagaagcgat actccgccta cggagaaaaa tacaagcttt taagagagaa
     4081 gtgggagata ccttgtttat tagtcctcgc tatcctaatg gagctacatg gagagaggaa
     4141 gccctacttg atactatttt tttagaaaac tttggccatg agctttatac tcaagcacct
     4201 aaagaaatcg ctagtctaat gaatgagtgg ctcgcttatt ttctatgagc tacttgtatt
     4261 gctggaaatg gtataagatg aaaatctaca agtcactaat tttcatataa caaaaaacga
     4321 acaggctctt tttctgttat tcagaagaga acttgttcgt ttttatcttg attttcttaa
     4381 aaagctctat atacataggg attttctggt ttatcgactt tggtaaagct gtcgatttcc
     4441 aaggttggaa ggttttgttt gagttcttta tggtagtgat tgaccagttt tcctttggct
     4501 gttatccaag tgttgttttc atactgccgg gtattgccct tggtcagcaa tccatagaca
     4561 ccagaatctg cgatacagtg gataatgccg aagcggaaca gaaattggct attggcatga
     4621 ctggggtcgt tatagacaaa gcctgtaaac tggattgtct tgccctcaaa ctcatctgga
     4681 tagtcgtaga tagcctccat gacttccata tagttttcat tagtgatctg aatactatct
     4741 tgggataagt atttatccgc cgccgttcgc atttcctttt cataggctga ttttgaaaaa
     4801 taagaactgg tatctggttt caaatattgg cttgtcgtcc cttcgcttgt ctgaatggct
     4861 agatccgttc cttctgatag ggggaaatga taacctttag cagaaacggt ctgagaatcc
     4921 aagctaacag ttgggaaagt taagccgatg acaagtggaa tagccagaag agaaatactc
     4981 gtcatcttgg ctaatcggct gttcagatga ctgtgggttt tgacttgctt catccagata
     5041 tacaattgaa caatagccaa gataaaggaa agcaccatgg aaatataggc cagataggaa
     5101 tagtgcatgt tgatgtactg gtttagtttg cccgacagat ggaggtaaat agtcagttca
     5161 aaatagccag ctaaaactaa aaatcgaatc ataggatgac tccaatcaag agagaatagg
     5221 ctaaaacgac cagagtcaca atcgtaatga agtgactaat aaatcgtgct ttcaagtaat
     5281 ttttcatcat gagaatattt ttgatatcca gcattgggcc aatgacgaga aaggccagaa
     5341 ctggagccaa accgaaactc gagagtagag aagcacctat aaaggcatcc gcctcactac
     5401 agagcgaaag aagaaaggcc aaaagcatca agagcaggat ggcaaaaaga ggagtcgcac
     5461 tgatagaggt cagaatccga gtcggaacgt agacctgtat tatagaagca aagaggcagc
     5521 caaataccaa ataacgcccc gtatcaaaaa attcatcaat ggcctgcaca aagacttgaa
     5581 aacctttttt tgcagaactc aagtaagaaa aatcatgctc atgacaagcc agacgatttt
     5641 ctttctgaat cggttcttgc cagaaaaatc ctagaaaaat tcctagtatt acagccacaa
     5701 gaatggaacc cagagctcgt aatagggcga catggaagga gttgccaaag gcagaatagg
     5761 tcgcaaaaag aacaatggga ttgataacag gtgctgtcac aagaaaagga acggccgtgt
     5821 aacttggaac ctttttttcc agaaaacgat tgatgatggg gacgattcca cattcacagg
     5881 aagggaaaag tataccgaca aaggtcccaa aaaagattct cccccaacga tttcgaggga
     5941 gaaaatgata aaccttgtca ggtgtgatat aaacttcaat cagccctgag acaatgcttc
     6001 ctatcagaac gaagggaagg gcttcaatga taatggagag aaaaatggct ccagtttgaa
     6061 gtacactaga tgggagttgt tgaaaagcag tcatctagtt tttcttttct gctttggctt
     6121 ttttctcttt gtcatcaggg aaagtgactt gtttcaaatc agggagttta gcaaactctt
     6181 caaacatctt gtccaagtcg tctcgttttg taaatttgac agccataggt gtacctcgat
     6241 tctaaattct acctctatta tactattatt ttgcggaaaa gggagttttt taatttgttt
     6301 tcgatagttg atactcttcg aaaatctctt caaaccacgt cagcttcgcc ttaccgtagt
     6361 acggttactg acttcgtcag ttctatccac aacctcaaaa cagtgttttg agctgacttc
     6421 gtcagttcta tccacaacct taaaacagta ttttgagcag cctacggcta gcttcctagt
     6481 ttgctttttg atttttattg agtatgaaaa ggattggaga aagctttcca gcttgtggta
     6541 taatagattt atggataaaa aatatgaaaa aatctctcag gatttgggag tgacgttaaa
     6601 gcaaattgat accgttctaa gtttgacagc tgaaggggcg actattccct ttatcgcgcg
     6661 ttatcgcaag gacatgactg gtagtctgga tgaggtggcg attaaggcta ttattgattt
     6721 ggataaaagt ctgacaaatc tcaatgaccg taaggaagct gtcttagcta agattcaaga
     6781 acaaggtaag ttgaccaagg aattggaaga agctatctta gttgccgaaa aattagcaga
     6841 cgttgaagaa ctctatcttc cttataagga aaagcgtcgt accaaggcaa ccattgcccg
     6901 tgaagctgga ctctttcctc ttgctcgctt gattttgcag aatatagttg acttagagaa
     6961 agaagctgaa aagttcgtct gtgaaggatt tgcgactggc aaggaagcct tgaccggtgc
     7021 agttgatatt ttggtcgaag ccttatcgga agatgtgacc ttgcgttcta tgacttatca
     7081 ggaagtgctg agacactcta aacttacttc tcaagccaag gatgaaagtc ttgatgaaaa
     7141 gcaggttttt cagatttatt atgatttttc agagacagtt ggaactatgc aaggctatcg
     7201 taccttggct ctcaatcgtg gggagaaact tggtgtcttg aagatcggtt ttgaacatgc
     7261 gacggaccgt attcttgcct tctttgctac tcgtttcaag gtgaaaaatg tttatattga
     7321 tgaagttgtt cagcaatccg ttaagaaaaa ggtcttgcct gctatcgagc gtcgtattcg
     7381 gacagaatta actgagaaag ctgaagaagg agctatccaa cttttttctg acaatctgcg
     7441 caatctcctc ttggttgctc cactgaaagg gcgcgtggtt cttggatttg acccagcctt
     7501 tcgtacaggt gccaagttag ctgtcgtgga tgcaacagga aaaatgctga caactcaggt
     7561 tatttatcct gttaaaccag catcagctcg tcaaatcgaa gaagccaaga aagatttagc
     7621 agatttaatt ggtcaatacg gtgtagagat tattgccatt ggaaatggaa cggccagtcg
     7681 tgaaagtgaa gcttttgtag cggaagttct gaaagatttc cctgaagtca gctatgttat
     7741 cgttaatgaa agtggtgctt ctgtctattc tgccagcgaa cttgctcgtc aggagtttcc
     7801 agacttgacc gttgaaaaac gttctgccat ttctatcgcc cgtcgtttgc aagatcctct
     7861 tgcggaattg gtcaaaatcg atcctaagtc aattggtgtc ggtcaatacc aacacgatgt
     7921 cagtcagaag aaactatctg agagtctgga ctttgttgtc gatacagtgg ttaaccaagt
     7981 tggtgtcaat gtcaatacag ctagcccagc tcttctttca cacgtagctg gactcaacaa
     8041 aactatctct gaaaatattg tcaaataccg cgaggaagaa ggaaaaatca cttcacgcgc
     8101 ccaaatcaag aaagttcctc gtctgggagc caaggccttt gagcaggctg ctggtttcct
     8161 tcgtatccct gaaagtagca atatccttga taatacagga gttcacccag agaattacac
     8221 tgcagttaag gaactcttca aacgtttaga tattaaagac ctaaacgaag aagcccaaag
     8281 caaactcaag tccctttcag tcaaggaaat ggctcaagag ctagacctcg gtccagaaac
     8341 ccttaaagat atcattgcag atcttctcaa accaggtcga gatttccgtg attcctttga
     8401 cgcacctgtg cttcgccaag atgtcctaga tatcaaagac ctagtggtag gtcagaagct
     8461 agaaggtgtt gtgcgtaacg ttgttgactt cggtgccttc gttgatatcg ggattcacga
     8521 ggacggcttg attcatattt ctcatatgag tcgcaagttt atcaaacacc ctagtcaagt
     8581 ggtgtcagtt ggagatttgg tgaccgtttg ggtcaagaaa attgatactg aacgtgaaaa
     8641 agttaatctg tcgctcctcg ctccaaatga aactgactga ttatgtcaag caggtttcac
     8701 tagaagactt cgggagagct tttatccatc atgtccagtg gaataggcgt ctacgttcga
     8761 caggtgggcg atttttcccc aaagatgggc atctggattt taatcccaag gtttatcaga
     8821 aactgggtat ggaggttttt aggaaaattg tccgacatga actctgtcat tatcaccttt
     8881 atttccaagg gaagggctat caacacaagg atcgggattt taaggaactt ttgaaagcag
     8941 tggatggatt acggtttgta ccatccttgc ccaatagtaa ctctaaacca ctcaagcttt
     9001 atcgttgtca atcctgccag caaaggtatc agcgcaagcg taggattgat accaaacgct
     9061 atcgctgtgg actttgtcga ggtaaattgc ttctgataaa tcagcctgag gactgatgaa
     9121 agccgagcct ccccgtgata tactatgtct aacctagcag aaagaggaaa tatcatgaac
     9181 agtaaatttt ataaaatgag acgcaatcgc atgatttcag gagttctggc aggtctgtca
     9241 gacaagtgga attttgatgt taccctagtt cgtttcttgt ttgctatttt tacagttgca
     9301 aactttggac ttggcgtgat tatctatatc atcctagctt ctatcatgcc taccaaggaa
     9361 gaaatcgaag cagaaatgta cggaacaggc ccacgtaaac gcaaagaagc ccaagccatt
     9421 gacgacaatg aaggctggtt ttggtgaggt tctacagaag atttggaata agcaaaaagc
     9481 tttaaatcaa tagtctaaac tgcttgattt aaagcttttt tacttttata ctcaataaaa
     9541 atcaaagtgc aaactaggaa gccagccaca ggctgtaatt tagtcggcaa tgtgaagttg
     9601 acatagtttg cactttgatt tttgaatagt attaataata tttcgccagc ttcatccaca
     9661 aactatagtg gattggaact agaatagtac acctctactt ctaaaacatt gttagaaatc
     9721 gatttgacta tcctgatcga tttgtcctgt tcttatttca ttttattata aaagcagtaa
     9781 tttaaacgca gttttttaat ctatttttgc tgctgagaca atatattttt ggaaaaatgg
     9841 tggatgctga taacaactga taaccagcaa ataacataag cagtgccggt aaattctgta
     9901 ccgataaagt gtgtgtgttc aactaagagc tgaccgatga atggagagag cagatagaga
     9961 agtccgatga gtatatgttc tttgtgtttc attaaagcgc accttctttc cttataggtt
    10021 gaacgacttg caagtgttaa attgaatggt atgttatcta ggtaacctta ctaaaatgtt
    10081 agttcccgct tcctcctttt caaagtaagc cttttcacac ttatatttta caactttaaa
    10141 aataggaaat caaatcattt tctaagtaat tttgcttata tttcacccaa tcttacaaaa
    10201 atgtaagatt aaagtctctt ttgtaaggtt aggttatggc aagcggtctt tttttgatgt
    10261 aaactagact cataaagaac aaaggagtaa catcatgaaa caaatcttac ataagaaaac
    10321 tagaaaacca agtcacaaag aaattgagcg cgttcagctg ggatgcacta tgatgcaagc
    10381 tacatttcat ttgatgggat attaagaaag gagattctca tgacactttt agatgtaaaa
    10441 cacgttcaaa aaatttataa aacacgtttt cagggcaacc aagtagaagc cctcaaggat
    10501 attcacttta ccgtcgaaaa gggtgactac gttgccatca tgggtgagtc tggttctggt
    10561 aaatcaactc ttctcaatat tctagctatg ctggataaac caagtcgtgg tcaggtttac
    10621 ttgaatggaa ctgacaccgc aaccattaaa aattcacagg cctctagctt ccgtcgtgaa
    10681 aagttgggct ttgtcttcca agactttaac ttgctagata ctctatctgt aaaggacaat
    10741 atcttgcttc cgcttgtctt gtcaagaaga cctattacag agatgatgaa gaaattggtg
    10801 gtgacagctg agaatctggg aataaaccaa ttacaagaga agtaccctta cgagatttct
    10861 ggtggtcaga aacagcgtgt agcagtagcc cgcgccatca tcacagaacc tgaaattctc
    10921 cttgcggacg aaccgacagg agctcttgac tccaagtcat ctgcagcctt acttgatgtc
    10981 tttgatgaaa tcaatgagcg cggccaaacc attctcatgg taacccactc aacagcagca
    11041 gctagcagag ctaaacgtgt actctttatc aaagacggca ttctttacaa tcaaatctac
    11101 cgtggagaga agacagaacg tcagatgttc caagaaatct ctgatacctt gactgtcatg
    11161 gcaagcgagg tgaattagta tgtttcgatt aaccaataag ttagcggtat cgaacttgat
    11221 taaaaaccgc aaactctact atccttttgc gctggctgtt ctcttggcag tcactgtcac
    11281 ctatctcttt tactctctaa ccttcaatcc taagattgcg gaaatccgtg gaggaacaac
    11341 cattcaggct acacttggat ttggtatgtt tgtcgtcacc cttgcgtcag ccattatcgt
    11401 tctctatgcc aatagttttg tcatgaagaa ccgttccaag gaactaggaa tttatggcat
    11461 gttgggcttg gagaagcgtc atcttatcag tatgaccttt aaggagttag tggtatttgg
    11521 gattctaact gttggagcgg gtatcggtat tggagccttg tttgacaagt taattttcgc
    11581 tttcctgctc aaactaatga aattgaaggt tgagctggtt gctaccttcc agacgaaagt
    11641 tgtcattaca gtgcttgttg tcttcggttt gattttccta ggcctcatgt tcctgaatgc
    11701 ccttcgaatc gcccgtatga atgccctcca gctctctcgt gagaaagcta gtggagagaa
    11761 aaaaggtcgc ttccttcctc tccaaaccat tcttggttcc ataagtttag gaattggcta
    11821 ttatcttgcc cttacggtaa aagatcctct tacagcctta acaaccttct tcatagctgt
    11881 tttactggtt atctttggga cttatctctt gtttaatgca gggattaccg ttttcctcca
    11941 aatcttaaag aaaaataaga aatactatta ccaaccaaat aacctcatat ctgtttctaa
    12001 cttgattttc cgtatgaaga aaaatgcagt tggactagcc accatcgcta tcttgtcaac
    12061 aatggttttg gtaaccatgt cagcagcgac aagcattttc aattcctcag aaagctttaa
    12121 aaaagttcta aatcctcatg attttggggt ttcagggcaa aatgttgaaa aagaagactt
    12181 ggacaaactc ttgagccagt ttgcaagtga caaaggttat aagattaaag aaaaagaagt
    12241 atttcgttac acttactttg ctgttgcgaa tcaagaagga accgagttaa ctatttttga
    12301 aaaaggacaa aaccgtgtcc aaccaaaaac aattttcatg gtatttgacc aaaaagatta
    12361 tgaaaatatg actggtcaaa aactgtctct atcaggaaat gaggtcggac tctttgcaaa
    12421 gaatgaggga gttaaagaac agaaaactct aattctgaat gatcatcaat tttctgtaaa
    12481 agaagaattt aataaagatt ttattgtcaa gcatgtccca aatcagttta atattttgac
    12541 tgctgattac aattaccttg ttgtacctga tttacaagcc tttttgaacc aattcccaga
    12601 ttcggctatc tataatcagt tttacggtgg tatgaatgta aatgtcagtg aagaagagca
    12661 actcaaagtc gctgaagaat atgaaaaata cttacaaaag tttaatgctc aattaaacac
    12721 tgaaggtaac tatgtgtatg gtagcactct agcagatgct agtgctcaaa tgagtgtcct
    12781 ctttggcggt gtcttcttta tcggtatttt cctatccatt atctttatgg tcggaaccgt
    12841 tctggtcatc tactacaaac aaatttctga aggctacgaa gaccgtgagc gctttattat
    12901 cttgcagaaa gtcggtttag atcaaaagca aatcaagcaa accatcaaca aacaggtttt
    12961 aactgtattc ttccttcctt tgctctttgc cttcctacat ctagcctttg cctaccatat
    13021 gcttagtctg attttaaaag tgattggtgt actggatacg actatgatgt tgattgtgac
    13081 cttgtctatc tgcgctatct tcctcatcgc ctatgtgctg attttcatga ttacttcaag
    13141 aagttatcgc aagattgtgc aaatgtaaaa aagatacctc gacttcaaaa tcgaggtatt
    13201 tcttgttttc taaatgctga aaagttgtcc gagcaggaag gtaactccca tagttaagag
    13261 accaatagca aggttccgaa tcatagctgt tttggttggg gcttttccaa gtctagcgct
    13321 tgtgtagcca gtgagaagaa gggctacacc gacgataagg acggtagcag ggatgcggta
    13381 atcacttgga aaaatggtca ctgacagcat tggaggcaaa cttctaagga aaaaggcaac
    13441 gaagctagaa atggcagcgt gccaaggatt ggtaaattct tcatactcaa tcccatattt
    13501 ttcctctacc agagccttga gtggattttt aagaaagatc ttattggtca agagttgggc
    13561 agaagttttg cattctccat tttggatata agcagcatag agggattttt tggctagttc
    13621 cctatcttgg tctaacaaga gtttttctcg cgaaacggca gcttcctcgg tatcttttgg
    13681 agttgaaacg gatacatatt ctccaccagc cattgaaaag gcaccagcta agatagccgc
    13741 aaatcctgat aaaaagataa tccagatatt ggtcgtggca ctggcaaccc cgataaccac
    13801 accagcaatg gaaataattc catcgttagc accaagaaca cctgcgcgca ggatatttaa
    13861 acgacctgca aaatttgaat cgatttcgtg atttgtttct gacgctaaat ttcaagttca
    13921 agttagccat ccagaagtct tctctgggtg acttgtagtc caagcatttt ttaggatagt
    13981 tgttaatcca cttttcgatg aatgcgactt ccttaggagt cattttcttg gttcccttag
    14041 gtaaccatct acgaatgaac ctgttgtgat tctcattagt tcccctttcc caagaggcat
    14101 aggggtgcgc ataataaatg tgctcctcag aaaatacatc agacaagcga ttgaattccg
    14161 ttccattatc tgccgtgatg gaaagaatct tgtgttgttt taagatgagt tttagagcct
    14221 gattgaccac ctcagcactt ttatttggaa tcaatcggat gatctgatgt ctactctttc
    14281 gatccgtcaa gacaagcaag cagtagtttt tcgatctcgt aagtagaacc gtatcaatct
    14341 cataatgccc attctccaag cgaagattga tagcttcagg ccgctgtgcg atggattgac
    14401 cagcaggttt aaagttggtg ctagcctgtt tcttaagcac ttttcctttt ctagggtaaa
    14461 gcagatcctg cttgcttaac cccaattttc catgatgaat ccaatagtaa atggttgaaa
    14521 ttcccacgtt aaccccttta gccatcacca tcatttcagg cgaaaatttt tggttatgat
    14581 agtggagaat cttttccttt agttcctttg tcaagcttga tttcttgacc gagcgcttgc
    14641 gattgttttc ataagactgt tgagcatagt cggcagaata aacctctttg aagcgccctt
    14701 ttccaagaca ttgtcggact gtcccacgct tgatttcagt gtggatagtt taaggagctt
    14761 ttccaagtag agaggcaatt tctctatttg atttcccttc ttttttccat ctttcgatta
    14821 agcgacggct atcgattgtc aaatgtttgg cttttgtagt ataattttct tgcatctctg
    14881 tgcctttctt gtgtttgtgg ttgaacaaca agtataacac agaggtgttt tcttatgcct
    14941 acaagagcta tcagctagtt gaaccatcta atttttagga gggctgggtg gctaacttca
    15001 ttatagaact ttcatttacg aacatatagt aaaatgaaac aagaacagaa caaatcgatc
    15061 aggacagtaa aatctatttc taataatgtt ttagaagcag aagtgtacta ttctagtttc
    15121 aatctattat atttttgttt tttatcaaaa aatactttac aagttcttaa aaacatgata
    15181 tagtaataaa gcttagaaaa tgagatgatg ttttctagca aatataaacc cgagtaaaaa
    15241 atgcctacgg acaggcaggg ttgaatgccg aagcgtggtt gaaaagccac attattgata
    15301 gggttaaaag cctactttta taagttgatg ttaggacact tgtcctaatt cataaatttt
    15361 tagtgtggtg aaagcacacg tcatcttgtg aaacgatcaa taaagtacgt aatatttgct
    15421 actagagagt taggaaacat cgggaacaga catactcaac agaaaccaaa ataaacacgt
    15481 cagaagattg cagagcaggt gaaaacctgc tcttttttca tgagtcaacc tttagttcct
    15541 tagttttcat aaggtcctaa aaatattgaa aggagtatgt tttgaaagag ttagatcaaa
    15601 accaagcccc aatttatgag gccttggtga agttacgcaa gaaaaggatt gttccctttg
    15661 atgttccagg tcacaagcgt ggacggggaa atccagaact tgtcgaactc ttaggagaaa
    15721 aatgtgtagg cattgatgtc aattcgatga aacccttgga taatttaggc catcctattt
    15781 cgattattcg tgatgcagag gagctggctg cagatgcttt tggagctagc catgcctttc
    15841 taatgattgg tggaacaact tcatcggtgc agactatgat tctggcaacc tgcaaggcag
    15901 gagataagat tattctgcca cgaaatgtcc ataaatctgc tatcaatgcg ttggttctat
    15961 gtggtgccat tcccatctat atcgagatga gtgtagatcc taagattggt atcgctttag
    16021 gtcttgaaaa tgaccgagta gcacaggcca taaaggacca tccagatgct aaggctatcc
    16081 taatcaacaa tcctacttac tacggcatct gttcagacct aaaggggttg acagaaatgg
    16141 ctcatgaagc tggcatgatg gttttagtag atgaagccca tggagcgcat ttgcatttca
    16201 ctggtaaact tccaatttct gctatggatg caggagctga tatggcagca gtttccatgc
    16261 ataagtctgg tgggagtttg acacaaagtt cgcttctttt aatcggggag cagatgaatc
    16321 ccgaatacgt tcgtcagatt ataaacctga cccagtctac atctgcctct tacttattga
    16381 tggctagttt ggatatttca cgtcgcaact tggcccttcg tggtaaagag tcgtttgagg
    16441 aagtcattga gctatccgag tacgctcgtc atgaaatcaa tgccattggc ggttactatg
    16501 cttactcaaa agagttaata gatggtgtgt cggtctgtga ttttgatgta accaagttgt
    16561 cagtttacac tcagggaata ggcttaacag gtatcgaggt ttatgacctc ttgcgagacg
    16621 aatacgacat tcagatcgag tttggtgata tcggcaatat cttggcctat atttccatcg
    16681 gcgaccgcat ccaagacatc gagcgcttgg ttggtgctct ggctgatatt aagagactct
    16741 attcacgaga tgggaaggac ttaatagctg gagaatatat tcagcccgag ttggtgctgt
    16801 ctccacaaga agccttctat tcagagagaa aaagtttgac cttagatgag tctgttggac
    16861 aggtctgtgg agaatttgtc atgtgctatc ctccagggat tcctatcttg gctcctggtg
    16921 aacgcattac acgagaaatt gtagactata tccaattcgc caaggaacgt ggttgctccc
    16981 tccaagggac ggaagatcca gaggtcaatc atatcaacgt tattaagaga aagacaaact
    17041 ataagaaaag tcaatagttt tatctaaact atttcttatt tcaatttgat gatttggcga
    17101 tgattttaga gcacggcaaa aagcccttga attagaagcg gtcaatcgct taatttctat
    17161 cagcttatca aatcctgcct caatcctttt ctgaggatta gggtagcgtg tcaagagttg
    17221 gtaggtatat tctgaatgct ttccaacgat tttatccaac tcaggaaaga tgatatcaag
    17281 acaacgagtg tattgtactt tccaatcaga ctgtttttct tgagacgatg aatatgtcta
    17341 gccagtattt ttagttctac ttgccgatta tcgtgttgaa attgttcacg attggggtca
    17401 gaaagaagtt taagagcgat gccatgagcg tctttcttat ccgttttagt cttgcgaagt
    17461 gataatgatt tggcaaattc cttgatgagc aaaggattgc aggtgtaaac tttatatcct
    17521 tgttcatgca ggaagttcag tagattaaag gcataatgtc cggtattttc aagagcgatg
    17581 agacagtctt ggttgagttg tcgaagagac agatctaaga gttcaaaacc agctttatta
    17641 tttgaaaaag tgagtggttt aagaacagtt tttcctggaa cattcaaggc tgtaacatcg
    17701 tgtttatttt tagcgacatc aatgcccaca taaagcatgg gagtacctcc agatgtagta
    17761 tttcaagtct acttggttat ccacgaattt tttgccttgt taccttagac gagataaaac
    17821 gtctatgcgt tatcaaactc attaccaatt gaaacaaaaa actgtggtta gagcctttcg
    17881 gaaatcgtca agcgattgga gggaataaac taatccacag tggcttattc caagtatacc
    17941 acttgggctt tggcagtagc taactgcgct aaatataata taaggagaaa tagatggatt
    18001 tatggttttc tgaagttcat actccagatg tcaaattgtc tctgagaaca gccaagcaac
    18061 tttacgctgg aaaaagtgaa tggcaggata tcgaagtctt ggatacgcca gcttttggga
    18121 aaatactgat tttaaatggc catgtcttgt tctcagatgc ggatgatttc gtctacaatg
    18181 aaatgaccgt tcacgttccc atggctgtcc acccaaatcc aaagaaagta ttggttattg
    18241 ggggtggtga cggcggtgtt gcccaagtat taacactcta tcctgaactg gaacaaatcg
    18301 atatcgtgga accggatgag atgttggtcg aggtctgtcg tgagtatttc ccagactttg
    18361 ctgcagggct agatgatcct cgtgttacca tttactacca aaatgggcta cgctttttgc
    18421 gaaactgcga agatgattac gatattatca tcaacgatgc gacagatcca tttggccata
    18481 cggaaggact ctttaccaag gaattctacg gcaatagtta tcgagctctg aaggaagacg
    18541 gcatcatgat ttaccagcat gggagtccct tctttgacga ggatgagtcg gcctgccgaa
    18601 gcatgcaccg caaggtcaat caatcctttc caatcagtcg ggtttatcag gcccatattc
    18661 caactagccc agctggctat tggttgtttg gatttgcatc gaaaaaatac caccctgtca
    18721 aagattttga caaggaaggt tggaaaaaac gccagctttt cacagaatac tacactgcaa
    18781 acttacacgt gggatccttt atgttgccca agtatgttga ggacatttta gaagaagagg
    18841 aaggaaaaaa atgagtcgtt tactagttat tggttgtggg ggcgttgccc aagttgctat
    18901 ttcaaagatt tgtcaagata gcgaaacatt tacagagatt atgattgcta gccgtaccaa
    18961 gtcaaaatgc gatgacttga aagcgaagct agaaggcaaa acaagtacta aaattgaaac
    19021 tgcagcactt gatgctgaca aggttgaaga agtgattgcc ctgattgaaa gctacaaacc
    19081 agaagctgtt ttgaatgtag ctctgcctta tcaagattta accattatgg atgcttgttt
    19141 ggcaacaggt gttcactata tcgatacagc caactacgaa gcagaagaca cagaagaccc
    19201 tgagtggcgt gctatctacg aaaaacgttg taaggaactt ggttttacag cctactttga
    19261 ctactcatgg cagtgggctt atcaagagaa attcaaagaa gcaggcttga ctgctcttct
    19321 tggttctggc tttgacccag gtgtaactag tgtcttttca gcttatgccc tcaaacacta
    19381 ttttgatgaa atccattata tcgacatttt agactgtaat ggcggtgacc acggttatcc
    19441 atttgcaacc aactttaatc cagaaattaa tctccgtgag gtttctgcgc caggttctta
    19501 ctgggaagat gggaaatggg tcgaagtcga agctatgtct atcaagcgtg agtatgattt
    19561 ccctcaagtt ggacaaaaag atatgtatct ccttcaccat gaagaaatcg aatcattggc
    19621 caagaacatt ccaggtgtca aacgcattcg tttctttatg acttttggtc aatcttactt
    19681 gacgcacatg aaatgtcttg aaaatgttgg actccttcgt acggatacca ttaactttaa
    19741 cggccaagaa attgttccaa ttcaattttt gaaagccttg cttccagatc ctgctagcct
    19801 tggcccacgt actgtaggta aaaccaatat tggatgtatc tttacaggtg tcaaagatgg
    19861 cgttgaaaag actatctaca tctacaatgt ttgcgaccat caagagtgct atgcagaagt
    19921 cgggtcacaa gcaatttcat acacgacagg cgttccagcc atgattggga caaaattagt
    19981 catgaacgga acttggaaac aagctggagt gtataacctt gaggagttag atccagatcc
    20041 attcatggaa gctttgaatg agtatggttt gccatgggtt gtggttgaaa atccacaaat
    20101 ggtggactaa tgaagttaga acaagtacca acaccagcct atgttattga cttggccaag
    20161 ttagaagcta attgccgcat tctacaatat gtacaagaag aggtcggttg caaggtcttg
    20221 cttgcccaga aggcatattc cctctacaaa acttatccct tgattagcca gtatctatca
    20281 ggtacgacag ctagtggact ctatgaggcc aaattggcaa gggaagaatt tcctggtgaa
    20341 gtccatgtat ttgcgcctgc tttcaaggat gcagacttgg aggaattgct tgggataaca
    20401 gaccatatcg tctttaactc agagagacag ttgcgtaagc atggggctcg ttgtcgagag
    20461 gctggtgtca gtgttggttt gcgcctcaac cctcagtgtt caactcaagg agatcacgcg
    20521 ctctatgacc cttgtgcacc aggttctcgc tttggagtta ctatagacaa gattccgagt
    20581 gatttgctag atttggttga cggacttcat tttcataccc tttgcgagca gggagcagat
    20641 gatttacaaa caactttgaa agcagtagaa gaacagtttg gtccctactt acatgaggta
    20701 aaatggctca atatgggtgg tggtcatcat attacaagag aaggttacga tgtggatttg
    20761 ctgatttcag aaatcaagcg tatccgaaaa acttacaatc ttgaaatcta tatcgagcct
    20821 ggtgaagcca ttgcgcttaa tgcgggttat ttagcaactg aggtattaga tattgtagaa
    20881 aacggtatgg aaatcttggt tttagacgcc tctgcgacct gccatatgcc tgatgtactt
    20941 gagatgccct atcgtccacc tttgagaaat ggctttgagg cacaggaaaa agcccatacc
    21001 tacagacttt cttctaatac ctgtctgacg ggcgatgtga ttggtgatta tagttttgaa
    21061 aatccagtcc aaatcggaga cagactttat tttcaagaca tggccattta ttcttttgtc
    21121 aaaaataata cctttaatgg tattggattg ccaagtctct atctcatgga cgaacaggga
    21181 gactgtagct tactcaaagc ttttggctat caagacttta aagggagatt atcatgatgg
    21241 acagtccaaa aaaattaggc tatcacatgc cagcagagta cgaaccccat catggtaccc
    21301 tcatgatatg gccgactcga ccaggatcat ggccttttca aggaaaggat gctaaaagag
    21361 catttactca gatcatcgag actatagcag aaggggaaag agtctatctt ttggtggagc
    21421 aggcctatct atctgaagcc caatcctatc ttggggacaa ggttgtttat ttagacattc
    21481 ccaccaatga tgcctgggcg cgtgatactg gcccaaccat tctcgtcaat gataaaggta
    21541 agaaattagc cgtggattgg gccttcaatg cttggggagg cacctatgat ggtctttatc
    21601 aagattatga agaggatgac caagtagcca gtcgttttgc tgaggccttg gaaaggcctg
    21661 tctatgatgc taaacctttt gtactggaag gaggtgcaat ccatagcgat ggtcaaggaa
    21721 ctattctcgt aactgaaagt tgcttgctta gtcctggtcg caatcctaac ttgactaaag
    21781 aggagattga aaacacatta ttagaaagtc ttggtgctga aaaagttatt tggcttcctt
    21841 atggtattta tcaggatgaa accaatgaac acgtcgataa tgttgctgcc tttgttggtc
    21901 ctgctgaggt tgttttggct tggacagatg acgaaaatga tccccagtat gccatgtcaa
    21961 aagcagatct cgaactctta gaacaggaaa cagatgcaaa aggttgtcac ttcaccattc
    22021 ataaattgcc tatccctgca gttcgacaag ttgtgacaga agaagatttg ccaggctaca
    22081 tctatgaaga aggagaagaa gagcgatacg caggtgaacg actagcagct tcctacgtaa
    22141 acttttatat cgccaacaag gctgtcttgg ttccacagtt tgaggatgta aacgaccaag
    22201 tggccttaga tatcctcagc aagtgtttcc cagaccgtaa agttgtcgga ataccagcca
    22261 gagatattct cttaggtggt ggcaatatcc actgtatcac ccaacaaatt ccagaatagg
    22321 agaaaaagat gagaaatgta agagttgcaa ccattcagat gcaatgcgct aaggatgtgg
    22381 caacaaatat ccaaaccgca gagcgtttag tacgtcaggc tgctgagcaa ggagcccaaa
    22441 ttattctctt gcccgagttg tttgaacatc cctatttctg tcaggaacgt cagtatgact
    22501 actaccagta tgcccaatct gtagcggaaa atactgccat tcagcatttt aaggtgattg
    22561 ctaaggaact acaagttgtt ttaccaatca gtttctatga aaaagatggt aatgtcttgt
    22621 ataactctat tgccgtcatt gatgcagatg gggaagtgct gggcgtttat cgaaagaccc
    22681 atataccaga tgaccattat tatcaagaaa aattctattt cacgcctggt aacactggtt
    22741 tcaaggtctg gaatactcgc tatgctaaga ttggtatcgg tatctgttgg gatcaatggt
    22801 tccctgaaac agcgcgctgt cttgcattga atggtgctga attgctcttt tatcctacag
    22861 ctatcggttc agagccaatt ttggatacag atagttgtgg tcactggcaa cgtactatgc
    22921 aagggcacgc agcagcgaat attgttccag tcatcgcagc caatcgttat ggtttagagg
    22981 aggttactcc tagtgaggaa aatggcggac agagttccag tcttgacttc tacggttcct
    23041 cctttatgac ggatgaaaca ggagctattc tagaacgagc tgaaagacaa gaagaagctg
    23101 ttctgttagc tacttatgac ctagacaagg gagcaagtga acgtctaaac tggggcttgt
    23161 ttcgagatag aagaccagaa atgtatagac aaattacaga ttagtgtggg agaaatgaga
    23221 gattcattct gctagactaa cttcttatta gcaactataa gatactatgg catctagtaa
    23281 atcgattttt atgattcgct attcttgtct attgattagt ccgtatttta aatattagca
    23341 aaaaagcaaa tagcagtaac ttctgtctat ttgcttttct tttttataga atatatttct
    23401 caatagcacg cgcaacgccg tcttcttcgt tgcttgaggt aacggcatcc gcaagagatt
    23461 tgacataatc gctggcattt cccattgcaa tcccaagccc tgcaaactgg agcatttcga
    23521 tatcgttatt agcatcgccc atggccataa tctctgagga atcaatcttc aaaatctcag
    23581 caagtcgtga aagagcagta gcctttgtcg ttccaagtgg cattgcttca taaatgacag
    23641 gctgcgaacg aactccactg aatcgttggc aaagctcttc agcaaaacgc tgctcaaaat
    23701 cgtctgtttg ttcttttgtt cctaaaaaca taccttggaa catccggaac tttccactag
    23761 tcgcttcttc aagagaaatt tcagtcaggt ctgaaaatac tagtttagca tcattttcaa
    23821 taacttgatt gggcttgcca ccgagaacaa aataatgtga ctcgtcaaaa agtgtcaact
    23881 gaacatcact cttttcagca aggtcataga ggtattcgat gtcagctgga ctcagttctt
    23941 gccagtcaac caagccccag tcgctagtct ggtgagttga acaaccgttg ttaacaatca
    24001 catattcgtt ctggaggtca agccccagtt ttttgtagta ggggaggaca ccgaaaaggg
    24061 ggcgacccgt acagaggacc agtttgacac ctttttcaat ggcttggtga atagcagcga
    24121 tgtgagcctg tgggatttcc ttggcttcat tgaggagggt tccatccata tccaaggcta
    24181 gtagtttaat cataggtctt ccttctttat cttttggtat tattatagca tattttggag
    24241 aagaaattga tagaaagctt gagactaatt gattttatag tttaagatgt tttgatgaca
    24301 attcatgatt tgaagaggat atttggcaaa gatatgctat actatgtttg tcaatgttgc
    24361 aactagacaa attaaaaaac caacttaata taatagtttt tttgtaagta ggtatgagta
    24421 tcagattact caactaatct aaacaataac ggaggaaata tatcatgatt ttaatgacaa
    24481 aaaatataaa tctaacaaat gaagaattag agctgataca aggtggagca gatccctatg
    24541 gtaaagaacc taatggttat tatccttggc aaatggaacc agtattaact atgccggttc
    24601 atggattttg tcccagagga accgatgatt tagtatatat tgtaggaggt aatcatcttt
    24661 gcaaaggaag tgctgcgaga ttttaagtaa aatttattag gaatatgaag aaacaagggg
    24721 agaaaacaga ggatttaata tgaaaaaacg agctattcaa attttactag cattgtcctt
    24781 aattttttac aaatcaactt ggttttggag gcttttcaat tatctcgcaa agccctatct
    24841 accagcaagt cgtgaatttt ttcagattct acttttgctg gaaagtggtg ttcttttgtc
    24901 agcagtcatc tatctactag tttttgcagg aaagaagatt tttcatttca agtggcagtt
    24961 gaggtacttt atctaccttt tactgggcta catcatttcg tatatgtctg actttctctt
    25021 ttcgtatttc atatccccgc cttcaaatca aatttctttg aatgaaacga tagaaatgat
    25081 gggacgacag gagttccctt atttcttgct catcgtttgc ttcatcgccc ctattgctga
    25141 ggaattgatt tatcgcggtg tgattatgac aacctttttc aaaaactcgc cttggtacgg
    25201 agatgttttg ctttctgcta ttattttcgg ttatattcat atcaattttg ctttaactcc
    25261 tcttgctttt ttcatttatg ctagtggagg tcttatttta gctctattgt atcgcatgac
    25321 taaaaatctc tactatccaa tactagttca tattctcatc aatatcactg ccttctggga
    25381 tgtgtggtta ctcctatttt caggaagtta gcttactaaa aaaatgtcgg aattttccgg
    25441 cattttcttt tttcacaaat agtcaacgtt tttctttccg atactgaagt ggtgtgtagc
    25501 cacttatttt tttgaattga ttttgaaaat aagattggcg tgagaaaggc agatagtgaa
    25561 gatagttaag aagaatagga tgttcttttt tcctttttgg aaaacttcta aaatatggta
    25621 taatgaaaag ataaagaagt tgggggtaga agatgaacat tcaacaatta cgctatgttg
    25681 tggctattgc caatagtggt acttttcgtg aagctgctga aaagatgtat gttagtcagc
    25741 cgagtctgtc tatttctgtt cgtgatttgg aaaaagagtt gggctttaag atttttcgtc
    25801 ggaccagctc agggactttc ttgacccgtc gtgggatgga attttatgaa aaagcgcaag
    25861 aattggttaa aggatttgat atttttcaaa atcagtatgc caatcctgaa gaagaaaaag
    25921 atgaattttc cgttgctagc cagcactatg acttcttacc accaactatt acggcctttt
    25981 cagagcgcta tcctgactat aagaacttcc gtatttttga atcaactact gttcaaatat
    26041 tagatgaagt ggcgcaaggg catagtgaga ttgggattat ctacctcaac aatcaaaata
    26101 aaaaggggat tatgcaacgg gttgaaaagt taggtctgga ggtcatcgaa ttgattcctt
    26161 tccataccca tatttatctc tgtgagggtc atcctttagc ccagaaagag gaattagtca
    26221 tggaggattt agcggattta ccaacggttc gtttcactca agagaaagac gagtaccttt
    26281 attattcaga gaactttgtt gataccagcg ctagctcaca gatgtttaat gtgacagacc
    26341 gtgccacctt gaatggtatt ttggagcgga cggacgccta tgcgacaggt tctggatttt
    26401 tagatagtga cagtgttaat ggcattacag ttattcgtct caaggataac ctagataacc
    26461 gcatggtcta tgttaaacgt gaagaagtgg agcttagtca agctgggact ctcttcgtag
    26521 aagtcatgca agaatatttt gatcaaaaga ggaaatcatg aaaaaaagag caatagtggc
    26581 agtcattgta ctgcttttaa ttgggctgga tcagttggtc aaatcctata tcgtccagca
    26641 gattccactg ggtgaagtgc gctcctggat tcccaatttc gttagcttga cctacctgca
    26701 aaatcgaggt gcagcctttt ctatcttaca agatcagcag ctgttattcg ctgtcattac
    26761 tctggttgtc gtgataggtg ccatttggta tttacataaa cacatggagg actcattctg
    26821 gatggtcttg ggtttgactc taataatcgc gggtggtctt ggaaacttta ttgacagggt
    26881 cagtcagggc tttgttgtgg atatgttcca ccttgacttt atcaactttg caattttcaa
    26941 tgtggcagat agctatctga cggttggagt gattatttta ttgattgcaa tgctaaaaga
    27001 ggaaataaat ggaaattaaa attgaaactg gtggtctgcg tttggataag gctttgtcag
    27061 atttgtcaga attatcacgt agtctcgcga atgaacaaat taaatcaggc caggtcttgg
    27121 tcaatggtca agtcaagaaa gctaaataca cagtccaaga gggtgatgtc gtcacttacc
    27181 atgtgccaga accagaggta ttagagtatg tggctgagga tcttccgcta gaaatagtct
    27241 accaagatga ggatgtggct gtcgttaaca aacctcaggg aatggttgtg cacccgagtg
    27301 ctggtcatac cagtggaacc ctagtcaatg ccctcatgta tcatattaag gacttgtcgg
    27361 gtatcaatgg ggttctgcgt ccagggattg ttcaccgtat tgataaggat acgtcaggtc
    27421 ttctcatgat tgctaaaaac gatgatgcgc atctagcact tgcccaagaa ctcaaggata
    27481 aaaagtctct ccgcaaatat tgggcgattg ttcatggaaa tctgcctaat gatcgtggtg
    27541 taattgaagc gccgattggc cggagtgaaa aagaccgtaa gaaacaggct gtaactgcta
    27601 aagggaagcc tgcagtgacg cgttttcacg tcttggaacg ctttggcgat tatagcttag
    27661 tagagttgca actggagaca ggacgcactc atcaaatccg tgtccacatg gcttatatcg
    27721 gccattcagt cgctggtgat gaggtctatg gtcctcgcaa gactttgaaa ggacatggac
    27781 aatttcttca tgccaagact ttaggtttta ctcatccgag aacaggtaag accttggaat
    27841 ttaaagcaga tatcccagag atttttaagg aaaccttgga gagattgaga aagtaagaat
    27901 gaaaaagaaa ttaactagtt tagcacttgt aggcgctttt ttaggtttgt catggtatgg
    27961 gaatgttcag gctcaagaaa gttcaggaaa taaaatccac tttatcaatg ttcaagaagg
    28021 tggcagtgat gcgattattc ttgaaagcaa tggacatttt gccatggtgg atacaggaga
    28081 agattatgat ttcccagatg gaagtgattc tcgctatcca tggagagaag gaattgaaac
    28141 gtcttataag catgttctaa cagaccgtgt ctttcgtcgt ttgaaggaat tgggtgtcca
    28201 aaaacttgat tttattttgg tgacccatac ccacagtgat catattggaa atgttgatga
    28261 attactgtct acctatccag ttgaccgagt ctatcttaaa aaatatagtg ataatcgtat
    28321 tactaattct gaacgtctat gggataatct gtacggttat gataaggttt tacagactgc
    28381 tgcagaaaaa ggtgtttcag ttattcaaaa tatcacacaa ggggatgctc attttcagtt
    28441 tggggacatg gatattcagc tctataacta tgaaaatgaa accgattcat cgggtgaatt
    28501 aaagaaaatt tgggatgata attccaattc cttgattagt gtggtaaaag tcaatggcaa
    28561 gaaaatttac cttgggggcg acttagataa tgttcatgga gcagaagaca agtatggtcc
    28621 tctcattgga aaagttgatt tgatgaagtt taatcatcat ttagatacaa aaaattctaa
    28681 tacaaaaaat tttataaaaa atttgtctcc tgagataatt gttcaaactt cctcctcacc
    28741 aattggttcg tatgatagcg gtcaagaaat aaatagggaa tatattagtt ggcttgaatc
    28801 aatgggaatt caacatataa atgcagccag caaagactat gatgcaacag tttttgatat
    28861 tcgacaagac ggtttaataa acatttcaac ttcctacaag cctattccaa gttttcaagc
    28921 tggttggcat aagagttcat atggaaactg gtggtatcaa gcgcctgatt ctacaggaga
    28981 atatgctgtt ggttggaatg aaattaaggg tgaatggtat tactttaacc aaacgggtat
    29041 cttattacag aatcaatgga aaaaatggaa caatcgttgg ttctatttga cagactctgg
    29101 tgttgctgct aaaaattgga agaaaatcgc tggaatctgg tattatttta acaaagaaaa
    29161 ccagatggaa attggttgga ttcaagataa agagcagtgg tattatttgg atgttgatgg
    29221 ctctatgaag acaggttggc ttcaatataa ggggcaatgg tattactttg ctccatcagg
    29281 ggaaatgaaa acgggctggg taaaagataa agaagcctgg tactatatgg attctactgg
    29341 tatcatgaag acaggtgaga tagaagttgc tggacatcat tactatctag aagaatcagg
    29401 agctatgaag caaggctggc ataaaaaggc aaatgattgg tatttctaca agacagacgg
    29461 ttcacgagct gtgggttgga tcaaggacaa ggataaatgg tacttcttga aagaaaatgg
    29521 tcaattactt gtgaacggta agacaccaga aggctatact gtggattcaa gtggtgcctg
    29581 gttagtggat gtttcgatcg agaaatctgc tacaattaaa actacaagtc attcagaaat
    29641 aaaagaatcc aaagaagtag tgaaaaagga tcttgaaaat aaagaaacga gtcaacatga
    29701 aagtgttaca aattcttcaa ctagtcaaga tttgacatcc tcaacttcac aaagctctga
    29761 aacgagtgta aacaaatcgg aatcagaaca gtagtagaaa agaaggtttt agggccttct
    29821 ttttcctatc aactcttttc tatttcctgt tattcatgtt ataatggata aatatgaata
    29881 atcggagtga gactatgaaa tacaaacgga ttgtctttaa ggtgggtact tcttctctga
    29941 caaatgagga tggaagttta tcacgtagta aggtaaagga tattacccag cagttggcta
    30001 tgctgcacga ggctggtcat gagttgattt tggtgtcttc aggtgccatt gcggctggtt
    30061 ttggagcctt aggatttaaa aagcgtccga ctaagattgc tgataaacag gcttcagcag
    30121 cggtagggca agggcttttg ttggaagaat atacaaccaa tcttctcttg cgtcaaatcg
    30181 tttctgcaca aatcttgctg acccaagatg attttgtgga taagcgtcgt tataaaaatg
    30241 cccatcaggc tttgtcggtt ttactcaatc gtggggcaat tcctatcatc aatgagaatg
    30301 atagtgtcgt tattgatgag gtcaaggttg gggacaatga cactctaagt gcccaagtag
    30361 cggcgatggt ccaagcagac cttttggttc tcttgacaga tgtggacggt ctctatactg
    30421 gaaatcctaa ttcagatcca agagccaaac gcttggagag aatagagacc atcaatcgtg
    30481 agattattga tatggctggt ggagctggtt cgtcaaacgg aactgggggt atgttaacca
    30541 aaatcaaggc tgcaactatc gcgacggaat caggagttcc tgtttatatc tgctcatcct
    30601 tgaaatcaga ttccatgatt gaggcggcag aggagaccga ggatggttct tactttgttg
    30661 ctcaagagaa ggggcttcgt acccagaaac aatggcttgc cttctatgct cagagtcaag
    30721 gttctatttg ggttgataaa ggggctgcgg aagctctctc tcaacatgga aagagtcttc
    30781 tcttatctgg tattgttgaa gcagaaggag ccttttctta cggtgatatc gtgacagtat
    30841 ttgacaagga aagtggaaaa tcacttggaa aaggacgcgt gcaatttgga gcatctgctt
    30901 tggaggatat attgcgttct caaaaagcca agggtgtctt gatttaccgt gacgactgga
    30961 tttccattac tcctgaaatc caactacttt ttacagaatt ttagaggtaa actatggtga
    31021 gtagacaaga acaatttgaa caggtacagg ctgttaaaaa atcgattaac acagctagtg
    31081 aagaagtgaa aaatcaagcc ttgctagcca tggctgatca cttagtagct gctactgagg
    31141 aaattttagc ggctaatgcc ctcgatatgg cagcggctaa ggggaaaatc tcagatgtga
    31201 tgttggatcg tctttatttg gatgcagatc gtatagaagc gatggcaaga ggaattcgtg
    31261 aagtggttgc cttaccagat ccaatcggtg aagttttaga aacaagtcag cttgaaaatg
    31321 gtttggttat cacaaaaaaa cgtgtagcta tgggtgtcat cggtattatc tatgaaagcc
    31381 gtccaaatgt gacgtctgat gcggctgctt tgactcttaa gagtggaaat gcggttgttc
    31441 ttcgtagtgg taaggatgcc tatcaaacaa cccatgccat tgtcacagcc ttgaagaagg
    31501 gcttggagac gactactatt cacccaaatg tgattcaact ggtggaagat actagccatg
    31561 aaagtagtta tgctatgatg aaggccaagg gctatctaga cctcctcatt cctcgtggag
    31621 gagctggctt gatcaatgca gtggttgaga atgcgattgt acctgttatc gagacaggga
    31681 ctgggattgt ccatgtctat gtggataagg atgcagacga agacaaggcg ctgtctatca
    31741 tcaacaatgc taaaaccagt cgtccttctg tttgtaatgc catggaggtt ctgctggttc
    31801 atgaagataa ggcagcaagc atccttcctc gcttggatca aatgctggtt gcagagcgta
    31861 aggaagctgg actggaacca attcaattcc gcttggatag caaagcaagc cagtttgttt
    31921 caggtcaagc agctgagacc caagactttg acaccgagtt tttagactat gtccttgctg
    31981 ttaaggttgt gagcagttta gaagaagcgg ttgcgcacat tgaatcccac agcacccatc
    32041 attcggatgc tattgtgacg gaaaatgctg aagctgcagc atactttaca gatcaagtgg
    32101 actctgcagc ggtgtatgtt aatgcctcaa ctcgtttcac agatggagga caatttggtc
    32161 ttggttgtga aatggggatt tctactcaga aattgcacgc gcgtggtcca atgggcttga
    32221 aggaattgac tagctacaag tatgtggtca ctggtgatgg acagataagg gagtaagaga
    32281 tgaagattgg atttatcggt ttggggaata tgggtgctag tttagccaag tctgtcttgc
    32341 aggctagacc gtcagatgag attctccttg ccaatcgtag tcaagtcaag gtggatgctt
    32401 tcatcgctaa cttcggtggt cagacttcta acaatgaaga aatattcgaa gaagcagatg
    32461 tgatttttct aggtgttaag cctgctcagt tttctgaact gctttctcaa taccagacca
    32521 tccttgaaaa aagagaaagt cttcttttga tttcgatggc agctggattg atcttagaaa
    32581 aactagcaag tcttatccca agccaacacc gaattattcg tatgatgcct aatacccctg
    32641 cttctatcgg gcaaggagtg attagttatg ccttgtctcc taattgcagg gctgaggaca
    32701 gtgagctctt ttgtcagctt ttatccaagg ctggtctctt ggttgaatta ggagaaagct
    32761 taatcaatgc agcgacaggt cttgcaggct gtggaccagc ctttgtctat ctctttattg
    32821 aggccttggc agatgcaggt gttcagacgg gattaccacg agaaacagcc ttgaaaatgg
    32881 cagcccaaac tgtggtagga gctgggcaat tggtcctaga aagccagcaa catcctggag
    32941 ttttgaaaga tcaagtttgt agtccaggcg gttcgactat tgctggcgta gcaagcctag
    33001 aagcgcatgc ttttcgagga acggtcatgg aggcagttca tcaagcctat aaacgaacac
    33061 aagaactagg taaataagag gtagttttat ctgcctcttt tatggtggtt gatactcttc
    33121 gaaaatcaaa ttcaaactgc gtcagcttca ccttgccgta ctcaagtaca gcctgcggct
    33181 agcttcctag tttgctcttt gattttcatt gagtatgaaa tgagaagaca aaaagattgt
    33241 cacaaacccc tatttttttg atagaataga agtagtaaaa aagaaatgag ttagacatgt
    33301 caaaaggatt tttagtctct cttgagggac cagagggagc aggcaagacc agcgttttag
    33361 aggctctgct accaatttta gaggtaaaag gggtaaaggt gctgacgacc cgtgaacctg
    33421 gcggagtctt gattggggag aagattcggg aagtgatttt ggatccaagt catactcaga
    33481 tggatgctaa aacagagcta cttctctata ttgccagtcg cagacagcat ttggtggaaa
    33541 aagttcttcc agcccttgaa gctggcaagt tggtcatcat ggatcgtttt atcgatagtt
    33601 ctgttgccta tcagggattt ggtcgtggct tagatattga agccattgac tggctcaatc
    33661 agtttgcgac agatggcctc aaacccgatt tgacactcta ttttgacatc gaggtggaag
    33721 aagggctggc tcgtattgct gctaatagtg accgcgaggt taatcgtttg gatttggaag
    33781 ggttggactt gcataaaaaa gttcgtcaag gctacctttc tctcctggaa aaagaaggaa
    33841 atcgcattgt caagattgat gctagtctcc ctttggagca agttgtggaa actaccaagg
    33901 ctgtcttgtt tgacggaatg ggcttggcca aatgaaacaa gatcaactaa aggcttggca
    33961 accagctcag tttgaccgtt ttgtccgtat cttagaacaa gaccagctca atcacgccta
    34021 tctcttttca ggtttctttg gaagcttgga aatggcgcaa tttttagcta agagcctctt
    34081 ttgtacggat aaagttggcg tcttaccatg tgagaaatgc cgaagttgca agctgattga
    34141 acaggaagag tttccagatg tcaccttgat taagccagtc aatcaggtca tcaagacaga
    34201 acgcattcgg gaattggtgg gacagttttc tcaagcaggg attgaaagcc agcaacaggt
    34261 ctttatcatc gagcaagcgg ataaaatgca tcccaacgca gccaattctc tgctcaaggt
    34321 catcgaagaa ccccagagtg aagtttatat tttcttcttg actagcgatg aggaaaagat
    34381 gttaccgaca atccgaagtc ggactcagat cttccacttt aaaaagcaag aagaaaaact
    34441 tatcttactc ttagaacaaa tgggacttgt taagaaaaaa gcgactcttt tagctaagtt
    34501 tagtcaatcg cgagctgaag cagaaaagtt ggctaatcag gcaagttttt ggaccttggt
    34561 cgatgaaagt gaacgcctgc tgacttggtt agtagctaag aaaaaagaaa gttatctaca
    34621 ggttgccaaa ttagccaact tggcagatga taaggaaaaa caggatcagg ttttacggat
    34681 tcttgaagtt ctctgtgggc aggacctctt gcaggtaaga gtaagagtga ttctacaaga
    34741 tttactagaa gctagaaaaa tgtggcaagc taatgtcagc tttcaaaatg ccatggaata
    34801 tctggtcttg aaagaaatat aaactcaaaa atgaatgata aagaaaggaa agggctgttt
    34861 tatggacaaa aaagaattat ttgacgcgct ggatgatttt tcccaacaat tattggtaac
    34921 tttagccgat gtggaagcca tcaagaaaaa tctcaagagc ttggtagaag aaaatacagc
    34981 tcttcgcttg gaaaatagta agttgcgaga acgcttgggt gaggtggaag cagacgctcc
    35041 cgtcaaggcc aagcatgttc gcgaaagtgt ccgtcgtatt taccgtgatg gatttcacgt
    35101 atgtaatgat ttttatggac aacgtcgaga gcaggacgaa gaatgtatgt tctgtgatga
    35161 gttgttatac agggagtaag catgcagatt caaaaaagtt ttaaggggca gtctccctat
    35221 ggcaagctgt atctagtggc aacgccgatt ggcaatctag atgatatgac ttttcgtgct
    35281 atccagacct tgaaagaagt ggactggatt gctgctgagg atacgcgcaa tacaggtctt
    35341 ttgctcaagc attttgacat ttccaccaag cagatcagtt ttcatgagca caatgccaag
    35401 gaaaaaattc ctgatttgat tggtttcttg aaagcagggc aaagtattgc tcaggtctct
    35461 gatgccggtt tgcctagcat ttcagaccct ggtcatgatt tggttaaggc agctattgag
    35521 gaagaaattg cagttgttac agttccaggt gcctctgcag gaatttccgc cttgattgcc
    35581 agtggtttag cgccgcagcc acatatcttt tacggctttt taccgagaaa atcaggccag
    35641 caaaagcaat ttttcgactc gaaaaaagac tatcctgaaa ctcagatttt ttatgaatcg
    35701 ccccatcgtg tggcagatac attggaaaat atgctagaag tctacggtga ccgctcggta
    35761 gtcttggtta gagaattgac caaaatctat gaagaatacc aaagaggtac aatttctgaa
    35821 ttgctggaaa gcatctctga aacgtctctc aagggtgaat gtcttctgat tgttgaaggt
    35881 gccagcaaag gtgtggagga aaaggatgag gaagacttgt tcttagaaat ccaagcccgt
    35941 atccagcaag gcatgaagaa aaatcaagct attaaggaag tcgctaagat ttaccagtgg
    36001 aataaaagtc agctctacgc tgcctaccac gactgggaag aaaatcaaga aaatgactaa
    36061 acagggaagt ttgccttctt cccttttttt gttatactag tagaagaaaa aattagaaag
    36121 atttgtgggt gttaaacaag ccagtgcctt gttttgatat gaacttaggt tccacccaaa
    36181 gaggtattag tgtcgtgtct caatcttata tcaatgttat cggtgctggt ttggcaggtt
    36241 ctgaagcagc ttaccaaatc gcagagcgtg gtattccagt taaactatat gaaatgcgtg
    36301 gtgtcaagtc tacaccccag cataaaacag acaattttgc tgagttggtt tgttccaatt
    36361 ctttgcgtgg ggatgctttg acaaatgcag ttggtcttct caaggaagaa atgcgtcgct
    36421 tgggttctgt tatcttggaa tctgctgagg ctacacgtgt tcctgccggt ggagcccttg
    36481 cggtggatcg tgatggtttc tctcaaatgg tgaccgaaaa agttgccaac caccccttga
    36541 ttgaagtggt tcgtgatgaa attacagaat tgccgacaga tgttattacg gttatcgcta
    36601 ctggtccttt gacaagtgat gccttggctg aaaagattca tgcccttaat gacggtgatg
    36661 gtttttattt ctacgatgcg gcagcgccta ttatcgatgt caacactatc gatatgagca
    36721 aggtctacct caaatcacgt tatgataagg gagaagcggc ctacctcaat gcccctatga
    36781 ccaagcaaga atttatggat ttccatgaag ctttggtcaa tgcagaagaa gcaccgctta
    36841 attcttttga aaaagaaaag tactttgaag gatgtatgcc tatcgaagtt atggccaaac
    36901 gtggcattaa aactatgctt tatggcccta tgaagccagt cggtcttgag tatccggacg
    36961 actacacagg acctcgtgat ggagaattta aaacacctta tgcggttgtg caacttcgtc
    37021 aggataatgc agctggtagc ctctacaata tcgttggttt ccagacccac ctcaaatggg
    37081 gagaacaaaa gcgtgtcttc caaatgattc cgggtcttga aaatgcggag tttgtccgtt
    37141 atggtgtcat gcatcgcaat tcttacatgg attcaccaaa tcttcttgag cagacttacc
    37201 gttccaagaa acaaccaaat ctcttctttg ctggtcagat gacgggggtg gaaggctatg
    37261 ttgagtcggc ggcttcgggc ttagttgcgg gaattaacgc agctcgtctc ttcaaggaag
    37321 aaagcgaggt tattttcccc gagacgacag cgattggaag cttagctcat tacattaccc
    37381 atgccgacag caaacatttc caaccaatga atgtcaattt tgggatcatc aaggagttgg
    37441 aaggcgagcg tatccgtgat aagaaggctc gttatgaaaa aattgcagag cgtgcccttg
    37501 ccgacttaga ggaatttttg actgtctaat ttttttgaaa gaattgctca tgatactata
    37561 aaaatcttag aaattgtgat aaaataggta ggatgaaaga aggagagtga aaatggcgaa
    37621 tcccaagtat aaacgtattt taatcaagtt atcaggtgaa gcccttgccg gtgaacgtgg
    37681 cgtagggatt gatatccaaa cagttcaaac aatcgcaaaa gagattcaag aagttcatag
    37741 cttaggtatc gaaattgcgc ttgttattgg tggaggaaat ctctggcgtg gagaacctgc
    37801 agcagaagca ggtatggacc gtgttcaggc agattacact ggaatgcttg ggactgttat
    37861 gaatgctctt gtgatggcag attcattgca acaagttggg gttgatacgc gtgtacaaac
    37921 agctattgct atgcaacaag tggcagagcc ttatgtccgt ggacgtgccc ttcgtcacct
    37981 tgaaaaaggc cgtatcgtta tctttggtgc tggaattggt tcaccatact tctcgacaga
    38041 tacaacagcg gcccttcgtg cagctgaaat cgaagcagat gccatcctca tggctaaaaa
    38101 tggcgtcgat ggtgtgtaca atgccgatcc taagaaggac aagacagccg ttaagtttga
    38161 agaattgacc caccgtgatg ttatcaacaa aggtcttcgt atcatggact caacagcctc
    38221 aaccctctca atggacaacg acattgactt ggttgtcttc aacatgaacc aatcaggcaa
    38281 catcaaacgt gtcgtatttg gtgaaaatat cggaacaaca gtttcaaata atatcgaaga
    38341 aaaggaataa gaaagaatat ggctaacgta attattgaaa aagctaaaga gagaatgacc
    38401 cagtctcacc aatcacttgc tcgtgaattt ggtggtatcc gtgctggtcg tgccaatgca
    38461 agcttgcttg accgtgtaca tgtagaatac tatggagtcg aaactcctct taaccaaatc
    38521 gcttcaatta cgattccaga agcgcgtgtt ttgttggtaa caccatttga caagtcttca
    38581 ttgaaagaca tcgaacgtgc cttgaacgct tctgatcttg gtatcacacc ggctaatgac
    38641 ggttctgtga ttcgcttggt tatcccagct cttacagaag aaactcgtcg tgaccttgct
    38701 aaagaagtga agaaggtcgg cgaaaatgct aaagtggctg tccgcaatat ccgtcgcgat
    38761 gctatggacg aagctaagaa acaagaaaaa gcaaaagaaa tcactgaaga cgaattgaag
    38821 actcttgaaa aagatattca aaaagtaaca gacgatgctg ttaaacacat cgacgatatg
    38881 actgccaaca aagagaaaga acttttggaa gtctaaaaat aaacagaaaa actcagttgg
    38941 cattgctggc tgagttttat tcgaaagaag gaaatatgaa tacaaatctt gcaagtttta
    39001 tcgttggact gatcatcgat gaaaacgacc gtttttactt tgtgcaaaag gatggtcaaa
    39061 cctatgctct tgctaaggaa gaaggccaac atacagtagg ggatacggtc aaaggttttg
    39121 catacacgga tatgaagcaa aaactccgcc tgacaacctt agaagtgact gccactcagg
    39181 accaatttgg ttggggacgt gtcacagagg ttcgtaagga cttgggtgtc tttgtggata
    39241 caggccttcc tgacaaggaa atcgttgtgt cactcgatat tctccctgag ctcaaggaac
    39301 tctggcctaa gaagggcgac caactctaca tccgtcttga agtggataag aaagaccgta
    39361 tctggggtct cttggcttat caagaagact tccaacgtct tgctcgtcct gcctacaaca
    39421 acatgcagaa ccaaaactgg ccagccattg tttaccgtct caagctatca ggaacttttg
    39481 tttacctacc agaaaataat atgcttggtt ttattcatcc tagcgagcgt tacgcagagc
    39541 cacgtttggg gcaagtatta gatgcgcgcg ttattggttt ccgtgaagtg gaccgcactt
    39601 tgaacctctc cctcaaacca cgctcctttg aaatgttgga aaacgatgct cagatgattt
    39661 tgacttattt ggaaagcaat ggcggtttca tgaccttaaa tgacaagtca tctccagacg
    39721 acatcaaggc aacctttggc atttctaaag gtcagttcaa gaaagcttta ggtggtctta
    39781 tgaaggctgg taaaatcaag caggaccagt ttggtacaga gttgatttag ggaggcttat
    39841 gagaaaatca ttttacactt ggctcatgac cgagcgcaat cctaaaagta acagtcccaa
    39901 agcaattttg gcagacctcg cttttgaaga gtcagccttt ccaaaacata cagatgattt
    39961 tgatgaggtc agtcgctttt tggaggagca tgccagtttc tcttttaacc taggagattt
    40021 tgacagcatt tggcaggaat atctagaaca ctagcattta ttcattgggt ttgggctagt
    40081 aatttctcca tccctctgct ataataaaaa gaaataaaag gattagagag gttctttatt
    40141 tgaaggaaca ttcaatagac attcaactga gtcatccaga tgacctgttt catctttttg
    40201 gttccaatga acgccatctt cgtttgatgg aagaagagct tgatgttgtg attcatgctc
    40261 gtacggagat tgtccaggtt ttgggagaag agtctgcctg tgaggaagcc cgtcaagtta
    40321 ttcaggcttt gatggtcttg gtaaatcgtg ggatgaccgt tggtacgcca gatgtagtca
    40381 ctgcgattag catggtcaaa aatgatgaaa ttgacaagtt tgtcgccctt tacgaagaag
    40441 aaattatcaa agataatact gggaaaccta tccgtgtcaa aaccctaggg caaaagcttt
    40501 atgtggacag tgtcaaacag catgatgtga cctttggaat tgggccagca ggtacaggga
    40561 agaccttcct tgcagtgacc ttggcagtga ctgcccttaa acgtgggcaa gtcaagcgaa
    40621 ttatcctaac tcgtccagcg gtggaagcgg gagagagtct tggatttctt ccgggtgatc
    40681 ttaaggagaa ggtggatcct taccttcgtc ctgtttacga tgccttgtat caaattcttg
    40741 ggaaagacca aacgactcgt ctcatggagc gtgaaattat cgaaattgcg ccccttgcct
    40801 atatgcgtgg tcggaccttg gatgatgcct ttgtcattct cgatgaggcg caaaatacga
    40861 ccatcatgca gatgaagatg ttcttgactc gtttaggttt tcattctaag atgattgtca
    40921 atggagatat tagtcagatt gatctgccac gtaatgtcaa gtccggtttg attgatgccc
    40981 aagaaaagct caagaacatt taccaaattg actttgttca tttttcagct aaggatgtgg
    41041 ttcgccatcc agttgtcgct cagattatcc gagcttatga accagctcca gttaaaaaag
    41101 aagagagtga agaattagag tctcaacctc tgtctgaagg atagttcttt tgtacttaaa
    41161 gttatctcaa tgctaagtat aaatttgctt tttaaatgtt ttattcaata tccttatatt
    41221 agattagaaa cgtttcaagc ggaggaaacg tatggaatca atatttgtga aatttgccca
    41281 gtatccgtct atagaaacgg agcgtttatt gcttagacct gtaactttgg atgatgcgga
    41341 agcaatgttt gactatgcct cggacaaggg taatacacgt tacacttttc caaccaatca
    41401 aagcttggaa gaaaccaaga ataacattgc tcagttctat ttggctaatc ccttgggacg
    41461 ttggggaata gaactaaaaa gcaatggtca gtttattgga accattgact tgcacaagat
    41521 tgattctgtt cttaagaagg cagctattgg ctacattatc aataaaaagt attggaatca
    41581 aggattaacg acagaagcca atcgtgctgt gattgagcta gcttttgaga agatagggat
    41641 gaataagttg actgcccttc acgataagga caatcctgcg tcaggaaagg tcatggagaa
    41701 atcaggcatg cgtttttccc atgcagaacc atatgcttgt atggaccagc atgaaaaaga
    41761 tcgaatcgtt acaagagttc attatgtctt gaccaaggaa gactattttg caaataaata
    41821 agcagttgaa aagaaatttt tcgactgttt tttcttcctc ttacgaataa tctaagagag
    41881 gagaaaatat ggaagcaatt atcgagaaaa tcaaagagta taaaatcatc gtcatctgta
    41941 ctggtctggg cttgcttgta ggcggatttt tcctgctaaa gccagctcca caaacacctg
    42001 taaaggaaac gaatttgcag gctgaagttg cagctgtttc caaggatttg gtatccgaaa
    42061 aggaagtgaa caaggaagag aaggaagaac cagttgaaca agatctaatc acagtagatg
    42121 tcaaaggtgc tgtcaaatcg ccagggattt atgacttgcc tgtaggtagt cgagtcaatg
    42181 atgctgttca gaaggctggt ggcttgacag agcaagcaga cagcaagtcg ctcaatctag
    42241 ctcagaaagt tagtgatgag gctctggttt acgttcctac taagggagaa gaagcagtta
    42301 gtcaacagac tggttcgggg acagcttctt caataagcaa ggaaaagaag gtcaatctca
    42361 acaaggccag tctggaagaa ctcaagcagg tcaagggact gggaggaaaa cgagctcagg
    42421 acattatcga ccatcgtgag gcaaatggca agttcaagtc agtagacgag ctcaagaagg
    42481 tctctggcat tggtggcaaa acaatagaaa agcttaaaga ctatgttaca gtggattaag
    42541 aatttctcta ttcccctaat ttacctgagt tttctattac tttggcttta ttacgctatt
    42601 ttctcagcat cttatcttgc tttgttgggc tttgtttttc tgctagtctg tctctttatc
    42661 caatttccgt ggaaatctgc tggtaaagtt ctaataattt gcggaatctt tggattttgg
    42721 tttgtttttc aaaattggca acagagtcaa gcgagtcaaa atctggcgga ttctgttgaa
    42781 agggtacgga ttttgcctga tactattaag gttaatggtg atagtctatc ctttcgtggc
    42841 aagtctaacg gtcgtgcttt ccaagtctat tataaactcc agtccgagga ggagaaagaa
    42901 gcctttcaag ctttaaccga cctgcatgag ataggactag aagggaagct ttcggagcca
    42961 gaagggcaga gaaattttgg tggctttaat taccaagcct atctgaagac tcagggaatt
    43021 taccagactc tcaatatcaa aacaatccag tcacttcaaa agattggcag ttgggatata
    43081 ggagaaaact tgtccagttt acgtcgaaag gctgtggttt ggattaagac gcactttcca
    43141 gaccctatgc gcaattacat gacaggactc ttgctgggac atctggacac cgactttgag
    43201 gagatgaatg agctttattc cagtctagga attatccacc tctttgccct atctggtatg
    43261 caggtaggtt ttttcatgaa tggatttaag aaacttctct tgcgattggg cttgacccaa
    43321 gaaaagttga aatggctgac ttatcccttt tcccttatct atgcgggact aactggattt
    43381 tcagcatcgg ttattcgcag tctcttgcaa aagctactgg ctcaacatgg ggttaagggc
    43441 ttggataatt ttgccttgac ggtgcttgtc ctctttattg tcatgccaaa ctttttcttg
    43501 acagcaggag gagtcttgtc ctgcgcttat gcttttatcc tgaccatgac cagcaaagaa
    43561 ggggaggggc tcaaggctgt tactagtgaa agtctagtca tctccttggg catattgccc
    43621 attctatcct tctattttgc ggaatttcaa ccttggtcta tccttttgac ctttgtcttt
    43681 tcctttctat ttgacttgac cttcttaccg ctcttgtcta ttttatttgt cctttccttt
    43741 ctctatccag tcattcagct gaactttatc tttgaatggt tggagggcat tattcgcttg
    43801 gtgtcacagg tgacaagtag acctctggtc tttggacaac ccaatgcatg gtttttaatc
    43861 ctattgttaa tttccttggc tttggtctat gatttgagaa aaaacattaa aaagctaacg
    43921 gtattgtgct tattgattac agggctcttt ctcctgatca agcatccact ggaaaatgaa
    43981 atcaccatgc tggatgtggg gcaaggagaa agtattttcc tacgggatgt aactgggaaa
    44041 accattctca tagatgtagg tggtaaggca gaatcttata agaaaatcga aaaatggcaa
    44101 gaaaagatga cgaccagcaa tgcccagcga accttgattc cctatctcaa aagtcgagga
    44161 gtagctaaga ttgaccagct aattttgact aacacggaca aggagaatgt tggagatttg
    44221 tcagaggtga ccaaggcttt ccatgtaggg gagattctag tatcaaaaga cagtctgaaa
    44281 cagaaggaat ttgtggcaga actacagacg actcaaacaa aggtgcgtag tatgacagta
    44341 ggggagaact tgcccatttt tggaagtcag ttagaagttc tatctccaag gaaaatggga
    44401 gatggaggac acgatgacac cctagttctg tatgggaaat tcttggataa gcaatttctc
    44461 ttcacgggaa atttggagga gaaaggagag aaggacttgc tgaagcacta tccagacttg
    44521 aaagtaaatg ttttgaaagc tagccaacat ggcaataaaa aatcatcaag tccagccttt
    44581 ctagaaaaac tcaaaccaga gcttactctt atctcagttg gaaagagcaa tcgaatgaaa
    44641 ctcccccatc aggaaacatt gacacgactg gaaggtatca atagcaaagt ttatcgaact
    44701 gaccagcaag gagctatacg ttttaagggg ttggatagtt ggaaaatcga aagtgttcga
    44761 taggaaggat aaatgttgta gattagtgaa ataaactaaa aatttgttgc ataataatga
    44821 taaaaatggt ataatgaaaa cgtattcaat attgaggata taaaatcatt aaaaatcagc
    44881 aaaagttgtt ttattagtta gtttataatc tattggtctt cttcagtcca gtgtatctgc
    44941 tgtgacagcc actaaaagtt acaagtatga ttggaatacg gttttggaat atagtaccaa
    45001 ctatcacgac catcagtatg cttggattcc ggaatggtct cgttattaca gctattctga
    45061 gtataaagtt ggcggaggct ggaactacgc tcgttatgag gtcataaact actatactgg
    45121 aggttattaa tccttaaaga gtgagaaaag gagggctgga tatgttaaat cttactcatg
    45181 ttaccttaaa aacgcgacaa gtcatcttgc aagatgcgga ttttaccttt aaaaagggta
    45241 ggatttatgg ccttcttgct atcaatggct cgggaaagac gacactattc cgagctatga
    45301 gcaagttgct tccccttagt agtggacaca tcgcagttcc tccttctttg ttttattatg
    45361 agagcgttga atggctggat ggaaacttaa gtgggatgga ctaccttcgt ctcataaaaa
    45421 acatctggaa gtcagaccta aacttgagag atgaaatcgc ctactgggaa atggctgact
    45481 atatcagtct tcccatccgc aagtattcct tagggatgaa gcaacgcttg gtgattgcta
    45541 tgtattttct cagtcaggcc aaatgctggc tcatggatga gattacaaat ggcttagacg
    45601 agtattatcg acagaagttt tttgataggc tagcacaaat cgatagacaa gaacagctgg
    45661 ttcttttaag ttcccactat aaggaagagt tggttgatat ctgcgataga gtagtaacca
    45721 ttcatcaggg gcagatagaa gaggtttagt ttatgaaaga tgttagtcta tttttattga
    45781 aaaaagtttt caaaagtcgt ttaaactgga ttatcttact tttatttgca tctgtactcg
    45841 gtgttacctt ttatttaaat agtcagactg caaactcaca cagcttggag agcaggttgg
    45901 aaagtcgcat tgcagccaac gagagggcta tcaatgaaaa tgaagagaaa ctctcccaaa
    45961 tgtctgatac cagctcggag gaataccagt ttgctaaaaa taatttagac gtgcaaaaaa
    46021 atcttttgac gcgaaagaca gaaattctaa ctttactaaa agaagggcgc tggaaagaag
    46081 cctactatct gcagtggcaa gatgaagaga agaattatga atttgtatca aatgacccga
    46141 ctgctagctc tggcttaaaa atgggggttg accgcgaacg gaagatttac caagccctgt
    46201 atcccttgaa cataaaagca catactttgg agtttccgac ccacgggatt gatcagattg
    46261 tctggatttt agaggttatc atcccaagct tgtttgtggt tgcgattatt tttatgctaa
    46321 cacaactatt tgcagaaaga tatcaaaatc atctggacac agctcactta tatcctgttt
    46381 caaaagtgac atttgcaata tcctctcttg gagttggagt gggatatgta actgtgctgt
    46441 ttatcggaat ctgtggcttt tcttttctag tgggaagtct gataagtggt tttggacagt
    46501 tagattatcc ctacccaatt tatagcttag tgaatcaaga agtaactatt gggaaaatac
    46561 aagatgtatt atttcctggc ttgctcttag ctttcttagc ctttatcgtc attgtggaag
    46621 ttgtgtactt gattgcttac tttttcaagc aaaaaatgcc tgtcctcttt ctttcactca
    46681 ttgggattgt tggtttattg tttggcatcc aaaccattca gcctcttcaa aggattgcac
    46741 atctgattcc ctttacttac ttgcgttcag tggagatttt atctggaaga ttacctaagc
    46801 aaattgataa tgtcaatcta aattggagca tggggatggt cttgcttcct tgcctgatta
    46861 tccttttgtt agtggggatt ctatttatcg aaagctgggg aagttcacgt aaaaaggaag
    46921 tttttaaagt ttagttttcc tatagggaag ctaaagaaaa actaacatag ggagagaatc
    46981 aacttggttc tctctttttg attcgaaaac caaaccaaaa tacaaacaca aacttttcaa
    47041 aaaataactt tttatcttga caagagctag aaaacttggt atcatataaa agttgagaaa
    47101 agcagaagtg agagcttctc gccttgtgac attaagttgc ctggccctac ggatgaaaag
    47161 tttcgaagaa acgctatcat aacgtgcggg cttgtatatt tacaagtccg ctattgtttt
    47221 tctctaataa aacaaaagag gtgaaaacca tagcaaagca agacttattc atcaatgatg
    47281 agattcgtgt acgtgaagtt cgcttgattg gtcttgaagg agaacagcta ggtatcaagc
    47341 cactcagtga agcgcaagct ttggctgata acgctaatgt tgacctagta ttgattcaac
    47401 cccaagccaa accgcctgtt gcaaaaatta tggactacgg taagttcaaa tttgagtacc
    47461 agaagaagca aaaagaacaa cgtaaaaaac aaagcgttgt tactgtgaaa gaagttcgtc
    47521 taagtccaac aattgacaag ggtgactttg atacaaaact tcgtaatgca cgtaagttcc
    47581 ttgaaaaagg aaataaagtt aaggtatcta ttcgctttaa gggtcgtatg attacccata
    47641 aagagattgg tgcaaaagtt ttagccgagt ttgctgaagc aactcaagat attgccatca
    47701 tcgaacaacg tgctaaaatg gatggacgtc aaatgttcat gcaattggcg ccagcgactg
    47761 acaaaaaata attgtcagaa agttaaataa aggagaaaaa atcatgccaa aacaaaaaac
    47821 acaccgcgca tcagctaaac gtttcaaacg tacaggttct ggtggactta aacgtttccg
    47881 tgcttacact tctcaccgtt tccacggaaa aactaagaaa caacgtcgtc atcttcgtaa
    47941 agcatctatg gtgcattcag gagattacaa acgtatcaaa gcaatgctta ctcgcttgaa
    48001 ataatagctt gactgtaagt aaacaattct aggaaatatt tggaggaaat aaaacatggc
    48061 acgtgttaaa ggtggcgttg tatcacgcaa acgtcgtaaa cgtattctta aattagcaaa
    48121 aggttactat ggagctaaac acatcttgtt ccgtactgca aaagaacaag taatgaactc
    48181 ttactactat gcataccgtg accgtcgtca gaaaaaacgt gacttccgca aattgtggat
    48241 tactcgtatc aatgcggcag ctcgtatgaa cggactttca tactcacaat tgatgcatgg
    48301 tttgaaattg gctgagattg aagttaaccg taaaatgctt gctgacttgg ctgttaacga
    48361 tgcagtagct ttcacagctc ttgcagatgc agctaaagca aaacttggta aataataact
    48421 gatgagactg gaacaggatt gtccagtctt tttaaaaata aaggagaaag atatggcttc
    48481 aaaaatgcta cacacttgct tacgagtaga aaatcttgaa aaatcaatcg cattttatca
    48541 agatgctttt ggttttaaag aattgcgtcg cagagatttt ccagaccatg ccttcacgat
    48601 tgtctatcta ggtcttgagg gtgatgatta tgagttggag ttgacttata actacgatca
    48661 cggtccgtat gtggttggtg atgggtttgc ccatatcgcc ctcagtacac ctgatcttga
    48721 ggcacttcat caagaacaca gtgcaaaagg ctatgaagtg actgagccaa atggtctacc
    48781 aggaactaca ccaaactatt actttgttaa agaccctgat ggatataagg tcgaagtcat
    48841 tcgtgaaaaa taatttcgtg caagttaagt agaatattcg ttttctactt gacttttttt
    48901 agctgaaaga gtatactaat aaaaattcaa cctttaaggg gagtccagag agactcacaa
    48961 ggtgtcagat aaaagaatag tgcaattttc tagaggagac cttttgagtg tgctctcttg
    49021 tgttgtacga ttttaactga ggccttgcac tagcaaggtc ttttctttat ctggtcccct
    49081 taaaatttaa ggaggaaaag ttatgaatct cacatgtaag aagcgtttgg gtgtcattcg
    49141 gttggaaacc atgaaggtgg ttgcacaaga ggaaatcgcg ccagcaatct ttgaattagt
    49201 cctagaagga gaaatggttg aagccatgcg agcaggccaa tttcttcatc tgcgtgtacc
    49261 agacgatgcc catctcttac gtcgtcctat ttcaatttcg tctattgaca aggcaaacaa
    49321 gcagtgtcac ctcatttatc ggattgaggg agctgggact gcaatttttt caaccttaag
    49381 tcagggagac actcttgatg tgatggggcc tcagggaaat ggttttgact tgtctgacct
    49441 tgatgagcag aatcaggttc tccttgttgg tggtgggatt ggtgttccac ccttgcttga
    49501 ggtggccaag gaattgcatg aacgtggagt gaaagtagtg acagtcctcg gttttgctaa
    49561 taaggatgct gttattttga aaacggaatt ggctcagtat ggtcaggtct ttgtaacgac
    49621 agatgatggt tcttatggca tcaagggaaa tgtttccgtt gttatcaatg atttagatag
    49681 tcagtttgat gctgtttact cgtgtggggc tccaggaatg atgaagtata tcaatcaaac
    49741 ctttgatgat cacccaagag cctatttatc tctggaatct cgtatggctt gtgggatggg
    49801 agcttgctat gcctgtgttc taaaagtacc agaaagcgag acggtcagcc aacgcgtctg
    49861 tgaagatggt cctgttttcc gcacaggaac agttgtatta taaggagaaa attatgacta
    49921 caaatcgatt acaagtgtct ctacctggtt tggatttgaa aaatccgatt attccagcat
    49981 caggctgttt tggctttgga caagagtatg ccaagtacta tgatttaaac cttttaggtt
    50041 ctattatgat caaggcgaca acccttgaac cacgttttgg gaacccaact ccaagagtag
    50101 cagagacgcc tgctggtatg ctcaatgcaa ttggcttgca aaatcctggt ttagaggttg
    50161 ttttggctga aaagctacct tggctggaaa gagaatatcc aaatcttcct attattgcca
    50221 atgtagctgg tttttcaaaa caagagtatg cagctgtttc tcatgggatt tccaaggcaa
    50281 ctaatgtaaa agctatcgag ctcaatattt cttgtcccaa tgttgaccac tgtaatcatg
    50341 gacttttgat tggtcaagat ccagatttgg cttatgatgt ggtgaaagca gctgtggaag
    50401 cctcagaagt gccagtttat gtcaaattaa ccccgagtgt gaccgatatc gttactgtcg
    50461 caaaagctgc agaagatgcg ggagcaagtg gcttgaccat gatcaatact ctggttggaa
    50521 tgcgctttga cctcaaaacc agaaaaccaa tcttggccaa tggaacaggt ggaatgtcag
    50581 gtccagcagt ctttccagta gccctcaaac tcatccgcca agtagcccaa acaacagacc
    50641 tgcctatcat tggaatgggg ggagtggatt cggctgaagc tgccctagaa atgtatctgg
    50701 ctggggcatc tgctatcgga gttggaacag ctaactttac caatccttat gcctgccctg
    50761 acatcatcga aaatttacca aaagtcatgg ataaatacgg tattagcagt ctggaagaac
    50821 tccgtcagga agtaaaagag tctctgaggt aaactgcaat caatctgttc ttgatttttt
    50881 attagtttgt aatatgaatt taggagaatt ttggtacaat aaaataaata agaacagagg
    50941 aagaaggtta atgaagaaag taagatttat ttttttagct ctgctatttt tcttagctag
    51001 tccagagggt gcaatggcta gtgatggtac ttggcaagga aaacagtatc tgaaagaaga
    51061 tggcagtcaa gcagcgaatg agtggatttt tgatactcat tatcaatctt ggttctatat
    51121 aaaagcagat gctaactatg ctgaaaatga atggctaaag caaggtgacg actattttta
    51181 cctcaaatct ggtggctata tggccaaatc agaatgggta gaagacaagg gagcctttta
    51241 ttatcttgac caagatggaa agatgaaaag aaatgcttgg gtaggaactt cctatgttgg
    51301 tgcaacaggt gccaaagtaa tagaagactg gatctatgat tctcaatacg atgcttggtt
    51361 ttatatcaaa gcagatggac agcacgcaga gaaagaatgg ctccaaatta aagggaagga
    51421 ctattatttc aaatccggtg gttatctact gacaagtcag tggattaatc aagcttatgt
    51481 gaatgctagt ggtgccaaag tacagcaagg ttggcttttt gacaaacaat accaatcttg
    51541 gttttacatc aaagaaaatg gaaactatgc tgataaagaa tggattttcg agaatggtca
    51601 ctattattat ctaaaatccg gtggctacat ggcagccaat gaatggattt gggataagga
    51661 atcttggttt tatctcaaat ttgatgggaa aatagctgaa aaagaatggg tctacgattc
    51721 tcatagtcaa gcttggtact acttcaaatc cggtggctac atggcagcca atgaatggat
    51781 ttgggataag gaatcttggt tttacctcaa gtttgatggc aaaatggctg aaaaagaatg
    51841 ggtctacgat tctcatagtc aagcctggta ctacttcaaa tccggtggtt acatgacagc
    51901 caatgaatgg atttgggata aggaatcttg gttttatctc aaatctgatg ggaaaatagc
    51961 tgaaaaagaa tgggtctacg attctcatag tcaagcttgg tactacttca aatccggtgg
    52021 ttacatgaca gccaatgaat ggatttggga taaggaatct tggttttacc tcaagtctga
    52081 tggcaaaatg gctgaaaaag aatgggtcta cgattctcat agtcaagcct ggtactactt
    52141 caaatctggt ggctacatgg cgaaaaatga gacagtagat ggttatcagc ttggaagcga
    52201 tggtaaatgg cttggaggaa aagctacaaa taaaaatgct gcttactatc aagtagtgcc
    52261 tgtcacagcc aatgtttatg attcagatgg tgaaaagctt tcctatatat cgcaaggtag
    52321 tgtcgtatgg ctagataagg atagaaaaag tgatgacaag cgcttggcta ttactatttc
    52381 tggtttgtca ggctatatga aaacagaaga tttacaagcg ctagatgcta gtaaggactt
    52441 tatcccttat tatgagagtg atggccaccg tttttatcac tatgtggctc agaatgctag
    52501 tatcccagta gcttctcatc tttctgatat ggaagtaggc aagaaatatt attcggcaga
    52561 tggcctgtat tttgatggtt ttaagcttga gaatcccttc cttttcaaag atttaacaga
    52621 ggatacaaac tacagtgctg aagaattgga taaggtattt agtttgctaa acattaataa
    52681 tagccttttg gagaacaagg gcgctacttt taaggaagcc gaagaacatt accatatcaa
    52741 tgccctttat ctccttgccc atagtgccct agaaagtaac tggggaagaa gtaaaattgc
    52801 caaagataag aataatttct ttggcattac agcctatgat acgacccctt acctttctgc
    52861 caagacattt gatgatgtgg ataagggaat tttaggtgca accaagtgga ttaaggaaaa
    52921 ttatatcgat aggggaagaa ctttccttgg aaacaaggct tctggtatga atgtggaata
    52981 tgcttcagac ccttattggg gcgaaaaaat tgctagtgtg atgatgaaaa tcaatgagaa
    53041 gctaggtggc aaagattagt actataagtg aatatgattt gagtgaatag taagttaaaa
    53101 atcctgattt caagtaaaat caggattttt tcatggatgc aatttttttg gagtctggtg
    53161 tgacgcggag ggtcttttgt cctgtgtaag tgacaaagcc gggttttcca ccagttggtt
    53221 tattgagttt tttgacttca atcatatcta cctgcaccag attcgacagg cgcccttgag
    53281 agaagtaggc agctaactct gctgcgtctg tcttgactgc atcagatggg tcaagatttc
    53341 ctgagatgac aacatggctt ccaggaatgt ccttagcatg gaaccaaagt tcctccttgc
    53401 gggccatttt aaaggtcaat tcctcatttt gaagattgtt tcgtccgaca tagatgatgg
    53461 ttttgccatc gcttgctaga tattgttcta gttttttgcg tttctggatt ttctcccgtt
    53521 gtcttctgcg gataaaacct gtttgaatca attcttcgcg gatttcagcg atttcttcca
    53581 gtccagcttg gttgaggacg gtttctacac tttccagata gagaatagtg gctttggttt
    53641 cttcaatcaa atcagtcaag tatttgacag cttctttgag tttctgatac cgtttaaaat
    53701 agcgttgggc attctggttg ggagtcagag ccttatcaag cgcaatcatg ataggttggt
    53761 tggtatagta gttgtctagg ataacctggt cttggtcgtt aggcacttgg tgtaggaagg
    53821 ttgtcagcaa ttctcctttt tgacgaaatt cttcagcgtt gtctgtcgcc agtaactctt
    53881 tttcctgttt tttgagtttg tgtcggtttt tctgaagttc attttcaaca cgacgaatca
    53941 gttcactggc ctgctgtttg acgcggtcgc gctcagcctt atccttatag taggtgtcca
    54001 acaaatcaga aagatttgca aaaggctctc ccacctgatt tgcaaaagga actggactga
    54061 aggaagtctc agtcaagcat ggcttggttt cctgattgaa aaaatttcgg aaagcggaaa
    54121 gtttttcact aaccagtatc ctttccaatt catttgccgt atcgcgtccc agaccttgaa
    54181 agaggctttg aagatttttt gctgttagtt cttgggtttg caggatttca aagagctttt
    54241 catccttgat agtaaaagga ttgagagatt ctgtacttgg cggagcgata taggtcgatc
    54301 ctggaagtaa ggtgcggtag ctattttgtg aaaagccgac gtgtttgata acttcgagga
    54361 ttttatgact gcttttatcg accagtagaa tattactgtg tttccccata atttcgataa
    54421 tcaaggtagc ctggatatgg tctccaatct cgtttttatt ggaaactgta atttccacaa
    54481 tacggtcatt ttccacttgc tcaatcgact caatcagggc cccctgcaaa tactttctca
    54541 aaaccatgat aaaggtagaa ggttgggctg gattttcaaa agtcgtttgg gtcagctgaa
    54601 tgcgtccaaa aactggatgg gcagaaagga gcaggcgatg gctttggcga ttgctgcgga
    54661 tttgcaagac caactcttgt tcaaaaggct gattgatttt ctggatgcga ccattcacta
    54721 attcgcttcg caattcctca actatgtggt gtaaaaaaaa tccgtcaaat gacatcgttc
    54781 tctccttgtg attgtattcc atagtattat atcaaaaagg tagaataaaa tcatggaaat
    54841 gtggtataat aaagccaagt aaagagaaac gagaagcaca tgtatattga aatggtagat
    54901 gaaactggtc aagtttcaaa agaaatgttg caacaaaccc aagaaatttt ggaatttgca
    54961 gcccaaaaat taggaaaaga agacaaggag atggcagtca cttttgtgac caatgagcgt
    55021 agtcatgaac ttaatctgga gtaccgtgac accgaccgtc cgacagatgt catcagcctt
    55081 gagtataaac cagaattgga aattgccttt gacgaagagg atttgcttga aaatccagaa
    55141 ttggcagaga tgatgtctga gtttgatgcc tatattgggg aattgttcat ctctatcgat
    55201 aaggctcatg agcaggccga agaatatggt cacagctttg agcgtgagat gggcttcttg
    55261 gcagtacacg gctttttaca tattaacggc tatgatcact atactccgga agaagaagcg
    55321 gagatgttcg gtttacaaga agaaattttg acagcctatg gactcacaag acaataaacg
    55381 aaaatggaaa aatcgtgact tgatatccag tttagaattt gccatcacag ggatttttac
    55441 tgctatcaag gaagaacgaa atatgcgaaa acatgcagtg acggctctag tggtcatcct
    55501 tgcaggtttt gtttttcagg tgtcacgaat cgaatggctc tttcttctat tgagtatttt
    55561 cttggtagta gcctttgaga ttatcaactc tgctattgaa aatgtggtgg atttggccag
    55621 tcactatcac ttttccatgc tggctaaaaa tgccaaggat atggcggccg gcgcggtatt
    55681 agtggtttct cttttcgcag ccttaacagg cgcattgatt tttctcccac gaatctggga
    55741 tttattattt taaacagtaa gaggaaatta tgacttttaa atcaggcttt gtagccattt
    55801 taggacgtcc caatgttggg aagtcaacct ttttaaatca cgttatgggg caaaagattg
    55861 ccatcatgag tgacaaggcg cagacaacgc gcaataaaat catgggaatt tacacgactg
    55921 ataaggagca aattgtcttt atcgacacac cagggattca caaacctaaa acagctctcg
    55981 gagatttcat ggttgagtct gcctacagta cccttcgcga agtggacacc gttcttttca
    56041 tggtgcctgc tgatgaagcg cgtggtaagg gggacgatat gattatcgag cgtctcaagg
    56101 ctgccaaggt tcctgtgatt ttggtggtga ataaaatcga taaggtccat ccagaccagc
    56161 tcttgtctca gattgatgac ttccgtaatc aaatggactt taaggaaatt gttccaatct
    56221 cagcccttca gggaaataac gtgtctcgtc tagtggatat tttgagtgaa aatctggatg
    56281 aaggtttcca atatttcccg tctgatcaaa tcacagacca tccagaacgt ttcttagttt
    56341 cagaaatggt tcgcgagaaa gtcttgcacc taactcgtga agagattccg cattctgtag
    56401 cagtagttgt tgactctatg aaacgagacg aagagacaga caaggttcac atccgtgcaa
    56461 ccatcatggt cgagcgcgat agccaaaaag ggattatcat cggtaaaggt ggcgctatgc
    56521 ttaagaaaat cggtagcatg gcccgtcgtg atatcgaact catgctagga gacaaggtct
    56581 tcctagaaac ctgggtcaag gtcaagaaaa actggcgcga taaaaagcta gatttggctg
    56641 actttggcta taatgaaaaa gaatactaag tagaggtggg ctcatgcctg cttcttgttt
    56701 tacagaagga ggacttatgc ctgaattacc tgaggttgaa accgtttgtc gtggcttaga
    56761 aaaattgatt ataggaaaga agatttcgag tatagaaatt cgctacccca agatgattaa
    56821 gacggatttg gaagagtttc aaagggaatt gcctagtcag attatcgagt caatgggacg
    56881 tcgtggaaaa tatttgcttt tttatctgac agacaaggtc ttgatttccc atttgcggat
    56941 ggagggcaag tatttttact atccagacca aggacctgaa cgcaagcatg cccatgtttt
    57001 ctttcatttt gaagatggtg gcacgcttgt ttatgaggat gttcgcaagt ttggaaccat
    57061 ggaactcttg gtgcctgacc ttttagacgc ctactttatt tctaaaaaat taggtcctga
    57121 accaagcgaa caagactttg atttacaggt ctttcaatct gcccttgcca agtccaaaaa
    57181 gcctatcaaa tcccatctcc tagaccagac cttggtagct ggacttggca atatctatgt
    57241 ggatgaggtt ctctggcgag ctcaggttca tccagctaga tcttcccaga ctttgacagc
    57301 agaagaagcg acagctattc atgaccaaac cattgctgtt ttgagccagg ctgttgaaaa
    57361 aggcggttcc accattcgga cctataccaa tgcctttggg gaagatggaa gcatgcagga
    57421 ttttcatcag gtctatgata agactggtca agaatgtgta cgctgtggta ccatcattga
    57481 gaaaattcaa ctaggcggac gaggcaccca cttttgtcca aactgtcaaa ggagggactg
    57541 atgagaaaaa tcatcggaat cactggggga attgcctctg gtaagtcaac tgtgacaaat
    57601 tttctaagac agcaaggctt tcaagtagtg gatgccgacg cagtcgtcca ccaactacag
    57661 aaacctggtg gtcgtctgtt tgaggctcta gtacagcact ttgggcaaga aatcattctt
    57721 gaaaacggag aactcaatcg ccctctccta gctagtctca tcttttcaaa tcctgaagag
    57781 caaaaatggt ctaagcaaat tcaaggggag attatccgtg aggaactggc tactttgaga
    57841 gaacagttgg ctcagacaga agagattttc ttcatggata ttcccctact ttttgagcag
    57901 gactacagcg attggtttgc tgagacttgg ttggtctatg tggaccgaga tgcccaagta
    57961 gaacgcttaa tgaaaaggga ccagttgtcc aaagatgaag ctgagtctcg tctggcagcc
    58021 cagtggcctt tagaaaaaaa gaaagatttg gccagccagg ttcttgataa taatggcaat
    58081 cagaaccagc ttcttaatca agtgcatatc cttcttgagg gaggtaggca agatgacaga
    58141 gattaactgg aaggataatc tgcgtattgc ctggtttggt aattttctga caggagccag
    58201 tatttctttg gttgtacctt ttatgcccat cttcgtggaa aatctaggtg tagggagtca
    58261 gcaagtcgct ttttatgcag gcttagcaat ttctgtctct gctatttccg cggcgctctt
    58321 ttctcctatt tggggtattc ttgctgacaa atacggccga aaacccatga tgattcgggc
    58381 aggtcttgct atgactatca ctatgggagg cttggccttt gtcccaaata tctattggtt
    58441 aatctttctt cgtttactaa acggtgtatt tgcaggtttt gttcctaatg caacggcact
    58501 gatagccagt caggttccaa aggagaaatc aggctctgcc ttaggtactt tgtctacagg
    58561 cgtagttgca ggtactctaa ctggtccctt tattggtggc tttatcgcag aattatttgg
    58621 cattcgtaca gttttcttac tggttggtag ttttctattt ttagctgcta ttttgactat
    58681 ttgctttatc aaggaagatt ttcaaccagt agccaaggaa aaggctattc caacaaagga
    58741 attatttacc tcggttaaat atccctatct tttgctcaat ctctttttaa ccagttttgt
    58801 catccaattt tcagctcaat cgatcggccc tattttggct ctttatgtac gcgacttagg
    58861 gcagacagag aatcttcttt ttgtctctgg tttgattgtg tccagtatgg gcttttccag
    58921 tataatgagt gcaggagtca tgggcaagct aggtgacaag gtgggcaatc atcgtctctt
    58981 ggttgtcgcc cagttttatt cagtcatcat ctatctcctc tgtgccaatg cctctagccc
    59041 ccttcaacta ggactctatc gtttcctctt tggcttggga accggtgcct tgattcccgg
    59101 ggttaatgcc ctactcagca aaatgactcc caaagccggc atttcgaggg tctttgcctt
    59161 caatcaggta ttcttttatc tgggaggtgt tgttggtccc atggcaggtt ctgcagtagc
    59221 aggtcaattt ggctaccatg ctgtctttta tgcgacaagc ctttgtgttg cctttagttg
    59281 tctctttaac ctgattcaat ttcgaacatt attaaaagta aaggaaatct agtgcgagta
    59341 aaaattaatc tcaaatgctc ctcttgtgac agtatcaatt acctaaccag taaaaattca
    59401 aaaacccatc cagacaagat tgaggtttta aagtattgtc ccaaggaaag aaaagtaacc
    59461 ctacatcttg aatctaagta gattttatgg taaaataata gggattttaa ggagtttgat
    59521 atgtataacc tattattaac cattttatta gtattatctg ttgtgattgt gattgcaatt
    59581 ttcatgcaac caaccaaaaa ccaatccagc aatgtatttg atgccagttc aggtgatttg
    59641 tttgaacgca gtaaagctcg cggttttgaa gctgtaatgc agcgtttgac agggatttta
    59701 gtctttttct ggctagccat tgccttagca ttgacggtat tatcaagtag ataagaaaat
    59761 aatgggcagg actaggtctt tgcctctttt tatttttaaa ggatgtttga gaaggtttta
    59821 cagtaaaaga aaattaaaaa atctagaaag aaaatatgaa agatagaata aaagaatatt
    59881 tacaagacaa gggaaaggtg actgttaatg atttggctca ggctttggga aaagacagtt
    59941 ccaaggattt tcgtgagttg attaaaacct tgtccttaat ggaaagaaag caccagattc
    60001 gctttgaaga agatggcagt ctgaccttgg aagccaagaa aaaacatgag attaccctca
    60061 aggggatttt tcatgcccat aaaaatggtt ttggttttgt cagcctagaa ggggaagagg
    60121 acgacctttt tgtagggaaa aatgatgtca actatgctat tgatggtgat accgtcgagg
    60181 tagtgattaa gaaagtcgct gaccgcaata agggaacagc agcagaagcc aaaattattg
    60241 atatcctaga acacagtttg acaacagttg tcgggcaaat cgttctggat caggaaaagc
    60301 ctaagtatgc tggctatatt cgttcaaaaa atcagaaaat cagtcaaccg atttatgtta
    60361 agaaaccagc cctaaagtta gaaggaacag aagttctcaa ggtctttatc gataaatacc
    60421 caagcaagaa acatgatttc tttgtcgcga gtgttctcga tgtggtggga cactcaacgg
    60481 atgtcggaat tgatgttctt gaggttttgg aatcaatgga cattgtatcc gagtttccag
    60541 aagctgttgt taaggaagca gaaagtgtgc ctgatgctcc gtctcaaaag gatatggaag
    60601 gtcgtctgga tctaagagat gaaattacct ttaccattga cggtgcggat gccaaggact
    60661 tggacgatgc agtgcatatc aaggctctga aaaatggcaa tctggagctt ggggttcaca
    60721 tcgcagatgt ttcttattat gtgaccgagg ggtctgccct tgacaaggaa gcccttaacc
    60781 gtgcgacttc tgtttacgtg acagaccgag tggtgccaat gcttccagaa cgactatcaa
    60841 atggcatctg ctctctcaat ccccaagttg accgcctgac ccagtctgct attatggaga
    60901 ttgataaaca tggtcgtgtg gtcaactata ccattacaca aacagttatc aagaccagtt
    60961 ttcgtatgac ctatagcgat gtcaatgata tcctagctgg cgatgaagaa aagagaaaaa
    61021 aatatcataa aattgtacca agtatcgaac tcatggccaa gcttcatgaa actttagaaa
    61081 acatgcgtgt gaaacgtgga gctctcaatt ttgataccaa tgaagcgaag attttagtgg
    61141 ataaacaagg taagcctgtt gatatcgttc ttcggcagcg tggtattgcc gagcggatta
    61201 ttgagtcttt tatgttgatg gctaatgaaa cagttgccga acatttcagc aagttggatt
    61261 tgccttttat ctatcgaatt cacgaggagc ctaaggctga aaaggttcag aagtttattg
    61321 attatgcttc gagttttggc ttgtgcattt atgggactgc cagtgagatt agtcaggagg
    61381 cacttcaaga catcatgcgt gctgttgagg gagaacctta tgcagatgta ttgtccatga
    61441 tgcttcttcg ctctatgcag caggctcgtt attcggagca caatcacggc cactatggac
    61501 tagctgctga ctattatact cactttacca gtccaattcg tcgttatcca gaccttcttg
    61561 ttcaccgtat gattcgagat tacggctgtt ctaaggaaat agcagagcat tttgaacaag
    61621 tgattccaga gattgcgacc cagtcttcca accgtgaacg tcgtgccata gaagctgagc
    61681 gtgaagtcga agccatgaaa aaggctgagt atatggaaga atacgtgggt gaagagtatg
    61741 atgcagttgt atcaagtatt gtcaaattcg gtctctttgt cgaattgcca aacacagttg
    61801 aaggcttgat tcacatcact aatctacctg aattttatca tttcaatgag cgtgatttga
    61861 ctcttcgtgg agaaaaatca ggtatcactt tccgagtggg tcagcagatc cgtatccgtg
    61921 ttgaaagagc ggataaaatg actggagaga ttgatttttc attcgtacct agtgagtttg
    61981 atgtgattga aaaaggcttg aaacagtcta gtcgtagtgg cagagggcgt ggttcaaatc
    62041 gtcgttcgga taagaaggaa gacaagagaa aattaggacg ctcaaatgat aagcgtaagc
    62101 attcacaaaa agacaagaag aaaaaaggaa agaaaccttt ttacaaggaa gtagctaaga
    62161 aaggagccaa gcatggcaaa gggcgaggga aaggtcgtcg cacaaaataa aaaggcacgc
    62221 cacgactata caatcgtaga tacgctagag gcagggatgg tcctgactgg aactgaaatc
    62281 aagagtgtac gagctgctcg aattaatctc aaggatggct ttgctcaagt gaaaaatgga
    62341 gaagtttggc tgagcaatgt tcatatcgcg ccttacgaag agggcaatat ctggaaccag
    62401 gaaccagaac gtcgtcgtaa actcctgctc cataaaaagc aaattcaaaa attggaacaa
    62461 gagaccaaag ggacaggaat gaccttagtt ccccttaagg tctatataaa agatggctac
    62521 gctaagcttc ttttaggact tgccaaaggg aagcatgact atgacaaacg ggagtctatc
    62581 aaacgtcgtg agcaaaatcg agatatcgcg cgtgtgatga aagctgttaa tcagcgataa
    62641 aaagaggaat tgaaaatgga aaaattagtt gcctataaac gcatgccttt gtggaataaa
    62701 caaacaatgc ctgaagctgt tcagcaaaag cacaatacaa aagttgggac ttgggggaaa
    62761 attactgtct tgaagggagc tctcaagttt attgaattga cagaagaagg ggaagttcta
    62821 gctgaacacc tctttgaagc aggggcagac aatccaatgg cccaacctca agcctggcac
    62881 cgagtggaag ctgccacaga tgatgtggaa tggtacttgg aattttattg taaacctgag
    62941 gattattttg ctaaaaaata caataccaat cctgttcatt cagaggtcct agaggccatg
    63001 cagacagtga aacaagggaa agctttggat ttgggttgtg gtcaggggcg taattctctt
    63061 tttctagccc agcaagattt tgatgtgacg gctgtagatc aaaatggact ggctcttgaa
    63121 atcttgcaaa gcattgtgga gcaggaagat ttggacatgc ctgttggcct ttacgatatc
    63181 aattcagcta gcattggaca agaatatgat tttatcgttt caacagttgt tctcatgttt
    63241 ctacaagcgg accgcattcc agctattatt caaaatatgc aggagaaaac cagtgttggt
    63301 ggttacaacc ttatcgtttg tgccatggac acggaggatt atccttgctc ggttaatttc
    63361 ccattcacct ttaaagaagg agaactggca gactattaca aggattggga attggttaag
    63421 tacaatgaaa atccaggcca tttgcatcgt cgcgatgaga atggcaatcg tattcaacta
    63481 cgctttgcga ccttactagc taagaaaatc aagtaaacac acatgaagat taggaatttt
    63541 cctgatcttt tttctttttt acgaatgata tagaaaagga gggaattcat gtttgttgcg
    63601 agagatgcta ggggagaatt ggtaaatgtg ttagaggata aacttgagaa gcaagcatac
    63661 acctgcccag cttgtggagg ccagctccat ttgcgtcaag gaccaagtgt acggacgcat
    63721 tttgcccata aatccttaaa agactgtgat tttttctttg aaaatgaaag tccagaacac
    63781 ctggccaata aggaatccct ctatcactgg ttgaaaaaag agacaaaggt tcaattagag
    63841 tacccgcttt cagaacttaa acagattgcg gatgtatttg taaatggcaa tctagctcta
    63901 gaagttcagt gtagtccctt gcctcagaaa gtccttaaag agcgaagtga gggatatcgt
    63961 agtcagggtt accaagtact gtggttgctg ggtcaaaaac tgtggctcaa ggagcgtttg
    64021 actcgtctac agcaaggttt tctttatttc agtcaaaaca tgggctttta tgtttgggaa
    64081 ttagacaagg aaaaacaagt tttaagactc aaatacctga tttaccagga tctccgcggt
    64141 aaactccatt atcaaatcaa ggaattttcc tatggtcaag gtagtttatt ggaaatattg
    64201 cgtcttccct ataagagaca aaaaatatct cattttacag tttctgagga caaggacatc
    64261 tgtcgctata tccggcaaca actttattat caaaatctct tttggatgaa agaacaagca
    64321 gaagcctatc aaaagggaga aaatatcctg acttatggac tgaaagaatg gtatccacaa
    64381 attcgaccaa tagtgggcaa atttttccag attgaacaag acttgactag ctattatcag
    64441 tacttttata cctattacca aaaaaatcct caaaatgatt ggcaaaagct ttatccacca
    64501 gccttttatc agcaatattt cttgaaaaat atggtagaat aaaaaggatg gaggaatcta
    64561 atggtattac aaagaaatga aataaatgaa aaagatacat gggatctatc aacgatctac
    64621 ccaactgacc aggcttggga agaagcctta aaagatttaa cagaacaatt ggagacagta
    64681 gcccagtatg aaggccatct cttggatagt gcggataacc tactagaaat cactgaattt
    64741 tctcttgaaa tggaacgcca gatggagaag ctttacgttt atgctcatat gaagaatgac
    64801 caggatacac gtgaagctaa gtatcaagag tactatgcca aggccatgac actctacagc
    64861 cagttagacc aagccttttc attctatgat cctgaattta tggagattag cgaaaagcag
    64921 tatgctgact ttttagaagc tcaaccaaag ctgcaggttt atcaacacta ttttgacaag
    64981 ctcttgcaag gcaaggatca cgttctttca caacgtgaag aagaattatt ggctggagct
    65041 ggagaaatct ttggttcagc aagtgaaacc ttcgctatct tggacaatgc ggatattgtg
    65101 ttcccttatg tcctagacga tgatggtaaa gaagttcagc tatctcatgg gacttacaca
    65161 cgtttgatgg agtctaaaaa acgtgaggtt cgccgtggtg cctatcaagc tctttatgcg
    65221 acttacgaac aattccaaca cacctatgcc aaaaccttgc aaaccaatgt taaggtgcaa
    65281 aattaccgtg ctaaagttcg taactacaag agtgctcgtc atgcagccct cgcagcgaat
    65341 tttgttccag aaagtgttta tgacaatttg gtagcagcag ttcgcaagca tttgccactc
    65401 ttacatcgct atcttgagct tcgttcaaaa atcttgggga tttcagatct caagatgtac
    65461 gatgtctaca caccgctttc atctgttgaa tacaatttta cctaccaaga agccttgaaa
    65521 aaagcagaag atgctttggc agtcttgggt gaggattact tgagccgtgt caaacgtgcc
    65581 ttcagcgagc gttggattga tgtttacgaa aatcaaggca agcgttcagg tgcctactct
    65641 ggtggttctt acgataccaa tgcctttatg cttctcaact ggcaggacaa tctggacaat
    65701 ctctttactc ttgttcatga aacaggtcac agtatgcatt caagctatac tcgtgaaact
    65761 cagccttatg tttacggaga ttactctatc tttttggctg agattgcctc aactaccaat
    65821 gaaaatatct tgacggagaa attattggaa gaagtggaag acgacgcaac acgctttgct
    65881 attctcaata acttcctaga tggtttccgt ggaacagttt tccgccaaac tcaatttgct
    65941 gagtttgaac acgccattca ccaagcagat caaaatgggg aggtcttgac aagcgatttc
    66001 ctaaataaac tctacgcaga cttgaaccaa gagtattatg gtttgagtaa ggaagacaat
    66061 cctgaaatcc aatacgagtg ggctcgcatt ccacacttct actataacta ctatgtatat
    66121 caatattcaa ctggctttgc ggccgcctca gccttggctg aaaaaattgt ccatggtagt
    66181 caagaagacc gtgaccgcta tatcgactac ctcaaggcag gtaagtcgga ctatccactt
    66241 aatgtcatga gaaaagctgg tgttgatatg gagaaggaag actacctcaa cgatgccttt
    66301 gcagtctttg aacgccgttt aaatgagttt gaagcccttg ttgaaaaaat aggattggca
    66361 taaaatggtt gaatcgtata gtaagaatgc taaccataac atgcgtcgtc ctgtcgtcaa
    66421 agaagaaatt gtagacttga tgcgtcagcg tcaaaagcaa gtcacaggtt ccttgaaaga
    66481 attggaagac tttgcccgca aggaaaatat tcctattatt ccccatgaaa cggttgctta
    66541 tttccgtttt cttatggaaa ccatgcagcc taaaaatatt ctggaaattg ggacggctat
    66601 cggtttttca gctctcttga tggctgaaca tgcgccaaat gctaagatta caactattga
    66661 tcgtaatcca gaaatgattg gttttgccaa ggaaaatttt gcccagtttg acagtcgcaa
    66721 gcaaatcact ctcctagagg gagatgcggt ggatgtctta tctacactga cagagtctta
    66781 tgatttcgtc tttatggatt ctgccaagtc taaatacatc gtctttctgc cagaaatcct
    66841 caaacatttg gaagttggtg gtgtggttgt cttggatgat atttttcaag gtggtgatgt
    66901 tgccaaggat attatggaag tccgtcgtgg tcagcgaacc atttatcgag gccttcaaaa
    66961 attatttgat gcaaccttag acaatccaga actcaccgca acattagtgc ctttaggaga
    67021 tggtattctc atgcttcgta aaaatgtagc agatgttcaa ctgtctgaaa gcgaatgatt
    67081 ttcagaaaaa tttaagaaaa aatagtaaaa tagatagagt aacacttatc tcaaaggagt
    67141 agacatgaag aaaaaattat tggcaggtgc catcacacta ttatcagtag caactttagc
    67201 agcttgttcg aaagggtcag aaggggcaga ccttatcagc atgaaagggg atgtcatcac
    67261 agaacatcaa ttttatgagc aagtgaaaag caacccttca gcccaacaag tcttgttaaa
    67321 tatgaccatc caaaaagttt ttgaaaaaca atatggctca gagcttgatg ataaagaggt
    67381 tgatgatact attgccgaag aaaaaaaaca atatggcgaa aactaccaac gtgtcttgtc
    67441 acaagcaggt atgactcttg aaacacgtaa agctcaaatt cgtacaagta aattagttga
    67501 gttggcagtt aagaaggtag cagaagctga attgacagat gaagcctata agaaagcctt
    67561 tgatgagtac actccagatg taacggctca aatcatccgt cttaataatg aagataaggc
    67621 caaagaagtt ctcgaaaaag ccaaggcaga aggtgctgat tttgctcaat tagccaaaga
    67681 taattcaact gatgaaaaaa caaaagaaaa tggtggagaa attacctttg attctgcttc
    67741 aacagaagta cctgagcaag tcaaaaaagc cgctttcgct ttagatgtgg atggtgtttc
    67801 tgatgtgatt acagcaactg gcacacaagc ctacagtagc caatattaca ttgtaaaact
    67861 cactaagaaa acagaaaaat catctaatat tgatgactac aaagaaaaat taaaaactgt
    67921 tatcttgact caaaaacaaa atgattcaac atttgttcaa agcattatcg gaaaagaatt
    67981 gcaagcagcc aatatcaagg ttaaggacca agccttccaa aatatcttta cccaatatat
    68041 cggtggtgga gattcaagct caagcagtag tacatcaaac gaatagtcca aatcaatgag
    68101 tcagggaaaa aactcgactt caggaaaaaa tgaagcaaac attcccacaa taaaacgcat
    68161 agtacaaggt ttgtactgcc ccccaaaaaa gttagacaat taatttatcc gaaggattta
    68221 gttctgtatt gcacagagct aagtcctttt agttttatct taattctctt attgttgtaa
    68281 taatcaatat agtctataat ggcttgttcc aattgattaa gtgatttaaa tgtttgctca
    68341 tagccataaa acatttcgga ttttaaaatg ccaaagaaag attccatcct accgttgtct
    68401 tggctgtttc ctttgcgtga catagatgct tgaattccct tactctctag gaagcgatga
    68461 taagaatcgt gttggtattg ccagccttgg tcactatgga gaatcgtatt ctcgtagtgc
    68521 ttctctttga atgctgttcc aaca
//
LOCUS       DAVLMQ010000006        67319 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000006 DAVLMQ010000000
VERSION     DAVLMQ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67319)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67319)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67319
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.006"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(181..1932)
                     /locus_tag="VXF95_000488"
     CDS             complement(181..1932)
                     /locus_tag="VXF95_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081077.1"
                     /translation="MKRQTVNQTLKRLAVDLASHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFVDRQGSGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKKSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGSA
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     TSDQVKGAISFKHVSFGYHPEKILIKDLSIDIPAGSKVAIVGPTGAGKSTLINLLMRF
                     YPISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEASREQVI
                     AAAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATS
                     SIDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMD
                     RKGKYYQMQKAAAFSSE"
     gene            complement(1934..3658)
                     /locus_tag="VXF95_000489"
     CDS             complement(1934..3658)
                     /locus_tag="VXF95_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081078.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VLVAILTIVIVGLSRLVNPFYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFWSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISVKRIEEVFVEAPEDIHSELEQKQATRDKVLQV
                     QELTFTYPDAAQPSLRYISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGFNQEVSDQELWQALEIAQAK
                     DFVSEKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNTSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYCEIN
                     ASQHGKED"
     gene            complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VXF95_000490"
     CDS             complement(3716..4654)
                     /gene="msrB"
                     /locus_tag="VXF95_000490"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1081079.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLI
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            complement(4796..4873)
                     /locus_tag="VXF95_000491"
                     /pseudo
     CDS             complement(4796..4873)
                     /locus_tag="VXF95_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(4949..5818)
                     /locus_tag="VXF95_000492"
     CDS             complement(4949..5818)
                     /locus_tag="VXF95_000492"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HEV1081080.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(5820..7106)
                     /locus_tag="VXF95_000493"
     CDS             complement(5820..7106)
                     /locus_tag="VXF95_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HEV1081081.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(7257..7994)
                     /gene="mecA"
                     /locus_tag="VXF95_000494"
     CDS             complement(7257..7994)
                     /gene="mecA"
                     /locus_tag="VXF95_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HEV1081082.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVVFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(8194..9228)
                     /locus_tag="VXF95_000495"
     CDS             complement(8194..9228)
                     /locus_tag="VXF95_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1081083.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(9257..10690)
                     /locus_tag="VXF95_000496"
     CDS             complement(9257..10690)
                     /locus_tag="VXF95_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HEV1081084.1"
                     /translation="MIDGKRLLFSLTIVSYALTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGILARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(10706..11692)
                     /locus_tag="VXF95_000497"
     CDS             complement(10706..11692)
                     /locus_tag="VXF95_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1081085.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATDLSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAEKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGHAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(11694..12797)
                     /locus_tag="VXF95_000498"
     CDS             complement(11694..12797)
                     /locus_tag="VXF95_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HEV1081086.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLARRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYTSKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYGIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFDVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(12787..13632)
                     /locus_tag="VXF95_000499"
     CDS             complement(12787..13632)
                     /locus_tag="VXF95_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1081087.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLCYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKQVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(13911..15185)
                     /gene="psr"
                     /locus_tag="VXF95_000500"
     CDS             complement(13911..15185)
                     /gene="psr"
                     /locus_tag="VXF95_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HEV1081088.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSSPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(15182..16030)
                     /gene="pheA"
                     /locus_tag="VXF95_000501"
     CDS             complement(15182..16030)
                     /gene="pheA"
                     /locus_tag="VXF95_000501"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HEV1081089.1"
                     /translation="MKIAYLGPKGSFSHHVVQTAFPHEELQAFANITDVIKAYEQGLV
                     NYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAENPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(16027..16503)
                     /locus_tag="VXF95_000502"
     CDS             complement(16027..16503)
                     /locus_tag="VXF95_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HEV1081090.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     LRIVADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(16496..17779)
                     /gene="aroA"
                     /locus_tag="VXF95_000503"
     CDS             complement(16496..17779)
                     /gene="aroA"
                     /locus_tag="VXF95_000503"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HEV1081091.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGASVIIEKECTRNHTEDMLKQFGGHLSVDSKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(17871..18209)
                     /locus_tag="VXF95_000504"
     CDS             complement(17871..18209)
                     /locus_tag="VXF95_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HEV1081092.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAQTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(18220..19323)
                     /locus_tag="VXF95_000505"
     CDS             complement(18220..19323)
                     /locus_tag="VXF95_000505"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HEV1081093.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(19333..20499)
                     /gene="aroC"
                     /locus_tag="VXF95_000506"
     CDS             complement(19333..20499)
                     /gene="aroC"
                     /locus_tag="VXF95_000506"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HEV1081094.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(20509..21576)
                     /locus_tag="VXF95_000507"
     CDS             complement(20509..21576)
                     /locus_tag="VXF95_000507"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HEV1081095.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWKVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSATIHPVSLEEMKDYLVK"
     gene            complement(21595..22449)
                     /locus_tag="VXF95_000508"
     CDS             complement(21595..22449)
                     /locus_tag="VXF95_000508"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HEV1081096.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATATNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(22439..23116)
                     /locus_tag="VXF95_000509"
     CDS             complement(22439..23116)
                     /locus_tag="VXF95_000509"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HEV1081097.1"
                     /translation="MKLIVSVMPRSLEEAQALDATRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQFYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(23113..24276)
                     /locus_tag="VXF95_000510"
     CDS             complement(23113..24276)
                     /locus_tag="VXF95_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HEV1081098.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGFDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHRFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(24961..26595)
                     /locus_tag="VXF95_000511"
     CDS             complement(24961..26595)
                     /locus_tag="VXF95_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081099.1"
                     /translation="MRLKVIKKLVDINILYSSQEANLANLRKKQAKNPGKKVNVSARV
                     LSSYIFSSLLMLICFSNIAIHFPFEEIPIYFSSMVAILLVLAFSTSFTAFYNVFYESK
                     DLASYRPYAFKESEIIMAKGLSVLLPALAGIVPILAYFLVLYIRLAPSLWLGLPLMLL
                     SLTLLFVSVTLVMVVAVHFLAQTTVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSTEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFFPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFVGVFIAVVNNNITSLHSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIYAVQSFLPVLTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLST
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(26576..27325)
                     /locus_tag="VXF95_000512"
     CDS             complement(26576..27325)
                     /locus_tag="VXF95_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081100.1"
                     /translation="MIEFQNVSKLYGDKKALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            27504..28958
                     /locus_tag="VXF95_000513"
     CDS             27504..28958
                     /locus_tag="VXF95_000513"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HEV1081101.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAENAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHREAFQVIEVDPVDRTVELGEPFTINGWTSFTFDGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKAVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQEDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(29048..31666)
                     /gene="alaS"
                     /locus_tag="VXF95_000514"
     CDS             complement(29048..31666)
                     /gene="alaS"
                     /locus_tag="VXF95_000514"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HEV1081102.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGQ
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNHNASQLSSKLVAIVADNAEVEAVSEGTTSLIFAETPFYAEMGGQVA
                     DHGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLAIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDVKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQPKIQELLDAVAGKL"
     gene            complement(31688..32173)
                     /locus_tag="VXF95_000515"
     CDS             complement(31688..32173)
                     /locus_tag="VXF95_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HEV1081103.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSEISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(32448..32687)
                     /locus_tag="VXF95_000516"
     CDS             complement(32448..32687)
                     /locus_tag="VXF95_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081104.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTVILSHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(32932..34002)
                     /locus_tag="VXF95_000517"
     CDS             complement(32932..34002)
                     /locus_tag="VXF95_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1081105.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIEGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDPQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQDS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(33999..34772)
                     /locus_tag="VXF95_000518"
     CDS             complement(33999..34772)
                     /locus_tag="VXF95_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081106.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIITGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(34769..35575)
                     /locus_tag="VXF95_000519"
     CDS             complement(34769..35575)
                     /locus_tag="VXF95_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081107.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWIMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(35556..36713)
                     /locus_tag="VXF95_000520"
     CDS             complement(35556..36713)
                     /locus_tag="VXF95_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081108.1"
                     /translation="MKKSIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRNIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFEPEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(36874..37779)
                     /gene="murB"
                     /locus_tag="VXF95_000521"
     CDS             complement(36874..37779)
                     /gene="murB"
                     /locus_tag="VXF95_000521"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HEV1081109.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARVVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQEMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(37891..38643)
                     /locus_tag="VXF95_000522"
     CDS             complement(37891..38643)
                     /locus_tag="VXF95_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HEV1081110.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFAKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(38653..39384)
                     /gene="budA"
                     /locus_tag="VXF95_000523"
     CDS             complement(38653..39384)
                     /gene="budA"
                     /locus_tag="VXF95_000523"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HEV1081111.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKGSGDQPEIGEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADVATHQPEYSRDNV
                     AGTIVGFWTPEIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            39526..40797
                     /locus_tag="VXF95_000524"
     CDS             39526..40797
                     /locus_tag="VXF95_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HEV1081112.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFEQALYCKANQLVLTSGTQQALFILSQISFP
                     RQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRSILNLAAKYDVYIVEDDYLGDLDSKKGQTFHYLDTEEHVIYI
                     KSFSTSLFPALRITALILPNAIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQPGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(40817..41632)
                     /locus_tag="VXF95_000525"
     CDS             complement(40817..41632)
                     /locus_tag="VXF95_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1081113.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEISSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKVDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANAVALRKNSDDLKEVVDKVIQKLKDEGIYQSYLEKAASLTEVEE"
     gene            complement(41789..42442)
                     /gene="phoU"
                     /locus_tag="VXF95_000526"
     CDS             complement(41789..42442)
                     /gene="phoU"
                     /locus_tag="VXF95_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1081114.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(42454..43212)
                     /gene="pstB"
                     /locus_tag="VXF95_000527"
     CDS             complement(42454..43212)
                     /gene="pstB"
                     /locus_tag="VXF95_000527"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1081115.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(43225..44028)
                     /gene="pstB"
                     /locus_tag="VXF95_000528"
     CDS             complement(43225..44028)
                     /gene="pstB"
                     /locus_tag="VXF95_000528"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1081116.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(44039..44923)
                     /gene="pstA"
                     /locus_tag="VXF95_000529"
     CDS             complement(44039..44923)
                     /gene="pstA"
                     /locus_tag="VXF95_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1081117.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(44913..45830)
                     /gene="pstC"
                     /locus_tag="VXF95_000530"
     CDS             complement(44913..45830)
                     /gene="pstC"
                     /locus_tag="VXF95_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1081118.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGIWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(45830..46708)
                     /gene="pstS"
                     /locus_tag="VXF95_000531"
     CDS             complement(45830..46708)
                     /gene="pstS"
                     /locus_tag="VXF95_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HEV1081119.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(47282..48586)
                     /locus_tag="VXF95_000532"
     CDS             complement(47282..48586)
                     /locus_tag="VXF95_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HEV1081120.1"
                     /translation="MQFPEGFVEKYKEILGDEARNFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQTFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKSSQVEQSVEIGQEAFVKYAAGEI
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(48587..49360)
                     /locus_tag="VXF95_000533"
     CDS             complement(48587..49360)
                     /locus_tag="VXF95_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HEV1081121.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLAPFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(49350..49628)
                     /locus_tag="VXF95_000534"
     CDS             complement(49350..49628)
                     /locus_tag="VXF95_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HEV1081122.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(49628..50029)
                     /locus_tag="VXF95_000535"
     CDS             complement(49628..50029)
                     /locus_tag="VXF95_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HEV1081123.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQH
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(50239..50856)
                     /locus_tag="VXF95_000536"
     CDS             complement(50239..50856)
                     /locus_tag="VXF95_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HEV1081124.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLALVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYENFFGYLYLKSRRK"
     gene            complement(50846..51619)
                     /locus_tag="VXF95_000537"
     CDS             complement(50846..51619)
                     /locus_tag="VXF95_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HEV1081125.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRGIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(51630..52367)
                     /locus_tag="VXF95_000538"
     CDS             complement(51630..52367)
                     /locus_tag="VXF95_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HEV1081126.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHAVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSVVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(52372..53502)
                     /locus_tag="VXF95_000539"
     CDS             complement(52372..53502)
                     /locus_tag="VXF95_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HEV1081127.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     HGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(53586..53975)
                     /locus_tag="VXF95_000540"
     CDS             complement(53586..53975)
                     /locus_tag="VXF95_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HEV1081128.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(53991..54374)
                     /locus_tag="VXF95_000541"
     CDS             complement(53991..54374)
                     /locus_tag="VXF95_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HEV1081129.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(54375..55163)
                     /locus_tag="VXF95_000542"
     CDS             complement(54375..55163)
                     /locus_tag="VXF95_000542"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HEV1081130.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGVLVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(55156..56091)
                     /locus_tag="VXF95_000543"
     CDS             complement(55156..56091)
                     /locus_tag="VXF95_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HEV1081131.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINTADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(56221..56397)
                     /locus_tag="VXF95_000544"
     CDS             complement(56221..56397)
                     /locus_tag="VXF95_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HEV1081132.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(56537..57244)
                     /locus_tag="VXF95_000545"
     CDS             complement(56537..57244)
                     /locus_tag="VXF95_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HEV1081133.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESNLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            57395..58423
                     /gene="queA"
                     /locus_tag="VXF95_000546"
     CDS             57395..58423
                     /gene="queA"
                     /locus_tag="VXF95_000546"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HEV1081134.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKVETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDSMFIY"
     gene            complement(59084..60211)
                     /locus_tag="VXF95_000547"
     CDS             complement(59084..60211)
                     /locus_tag="VXF95_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_135354310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1081135.1"
                     /translation="MNTSFVHAADGIQYVRDDTRDKEEGIEYDDADNGDIIVKVATKP
                     KVVTKKISSTRIRYEKDETKDRSENPVTIDGEDGYVTTTRTYDVNPETGYVTEQVTVD
                     RKEATDTVIKVPAKSKVEEVLVPFTTEYEADNDLSAGQEQEITLGKNGKTVTTITYDV
                     DGKSGQVTESTLSQKEDSQTRVVKKGTKPQVLVQEIPIETEYLDDPTLDKGQEVGEIG
                     KITLTTIYAVDERDGTIEETTSRQITKEMVKRRIRRGTREPEKVVVPEQSSIPSYPVS
                     VTSNQGTDVAVEPAKAVAPTTGWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGS
                     MKVNQWFQVGGKWYYVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(60926..61477)
                     /locus_tag="VXF95_000548"
     CDS             complement(60926..61477)
                     /locus_tag="VXF95_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081136.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PNPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(61875..62699)
                     /gene="nadE"
                     /locus_tag="VXF95_000549"
     CDS             complement(61875..62699)
                     /gene="nadE"
                     /locus_tag="VXF95_000549"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HEV1081137.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRSETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(62696..64156)
                     /locus_tag="VXF95_000550"
     CDS             complement(62696..64156)
                     /locus_tag="VXF95_000550"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HEV1081138.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEGLRFSDSDIAYLELLGYHGAFLNYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(64272..64760)
                     /locus_tag="VXF95_000551"
     CDS             complement(64272..64760)
                     /locus_tag="VXF95_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081139.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(64750..64959)
                     /locus_tag="VXF95_000552"
     CDS             complement(64750..64959)
                     /locus_tag="VXF95_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1081140.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(65344..66072)
                     /locus_tag="VXF95_000553"
     CDS             complement(65344..66072)
                     /locus_tag="VXF95_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081141.1"
                     /translation="MKLNKLNFLKENIRNLYSSGVIYLSLLISFIPPILLTFFILKTQ
                     ETSLGIKHISNFYAMLGMLMAVIHANRVISRDFSHNTVSLFYNQQKNRMIYVLSNFLY
                     AISVSIIYALNGIVLLVIVSKLGIPGDLGLDFIVAIVVNTILLVLFYFLLSYIFYLYK
                     LKSGLVFGILVALLLFIPNILNTMMMNTSNDLFIKAIELLPFYSLPVFVASNTMSISQ
                     YLVVITTIILLYFFTLKKSKKYSF"
     gene            complement(66088..66879)
                     /locus_tag="VXF95_000554"
     CDS             complement(66088..66879)
                     /locus_tag="VXF95_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081142.1"
                     /translation="MNFALNKGEIVGLVGRNGVGKSTLMKILVQNNQPTSGNIISSDN
                     IGYLIEEPKLFLSKTGLENLKYLSNLYGVDYNQERFRSLIQELDLTQSINKKVKTYSL
                     GTKQKLALLLTLVTKPDILILDEPTNGLDIESSQIVLAVLKKLALNENVGILISSHKL
                     EDIEEICERVLFLESGLLTFQKVGKDSHNFLFEIAFSSATDRDIFITKQEFGDIVQEE
                     GLRITMSGNIQSSELFKFFNENSIKVVDFETKKETLKDIYLNRSK"
BASE COUNT        20084 a        15168 c        12468 g        19599 t
ORIGIN      
        1 ctgacttcgt cagtcttatc tacaacctca aagctgtgct ttgagcaacc tacggctagc
       61 ttcctagttt gctctttgat tttcattgag tattacagtg aacaattttt ctagctattg
      121 taacaaaaaa gtcactcgaa ggcaactttt ttcgtccata aactttcaaa agagaatggc
      181 ttattcagaa ctaaaagccg cagctttttg catttggtaa tacttaccct ttctatccat
      241 gagttcttga tggttaccat attcaacaat atcaccatct actaagacaa gaattaaatc
      301 cgcatcctga atggttgaca aacggtgagc aatgatgaaa cttgtgcggc ccttcatgag
      361 ttttgcaaag gcatcctgta ccagcacttc tgtccgtgta tcaatggaag aagttgcctc
      421 gtctaagata agaatctttg gaatagccag aaagactcgg gctatggtca agagctgagc
      481 ttggccgaca gagagagatt ctccagcatt ttccaacttg gtatcgtatc cctgtggcaa
      541 ctgttggatg aaaaagtctg cattagctgc tttggcagca gcaattactt gctctcgact
      601 ggcttcagga ttgccaaagg caatattatc atgaatggtc ccttgtgtga gccaggtttc
      661 ttgaagcacc ataccaaact gctgtctcaa tgatactcgt gtataatcat aaatggattg
      721 cccatccagc aagatatctc ccgagctaat gggataaaaa cgcataagga gattgataag
      781 agttgatttt ccagcacctg tcggaccaac gatggctacc ttactaccag ctggaatatc
      841 gatagacaag tccttaatca aaattttttc aggatggtag ccaaaagaga catgtttaaa
      901 ggaaatagct cccttaactt ggtcactggt cgtcaagact tccttacctg tttcagccac
      961 ttcagggcta tctaagactc catagatacg ctctacgcaa gccagagcac tttgcaactc
     1021 agctagcact gaagaaatat cgttaaaggg cttggtgtat tgctgaacat agttcaaaaa
     1081 agtcactaaa cgaccgacgg tcaaggctga acccatcatg atacgataag ctcctactcc
     1141 agctaaaagg gcataaatga gtgcatttac aaagcgagtc gaaggattga ccgttgaaga
     1201 ataaaagatg gctgactgag aatagcctga gtagttgtca tgagcctcac gcaatctttg
     1261 gataaattct gtttgagcat tgaaggactg gattatagtc tgctgactaa gcgattcttc
     1321 aatcaactga gtctgaattc ccctcgtctc tgtttgcttc tggaagagat gataggattt
     1381 cttggcaata aagcgtgaaa tcaccatgga cagtggcgtc aacagcaaga ctaagagagt
     1441 catgaggaga tgaatttgga gcatggctag aatactgacc aaaatcatca aaacaccaat
     1501 gaaaaattgg ttaaaaatca tggtcaagcc agctgccaac tgttcgatgt ccgtggttac
     1561 acgactaacc atctctccac taccttgcct atctacaaag gcaatcggta aacgatggag
     1621 cttatggatg attcgctccc gtaaatctct ggtataagag aagattagac gattatagag
     1681 gagaggattg gcccattgta ccagagtatt tcctattacc accaagagca tctggagaaa
     1741 aatctgccaa aaaactggtg atgaaccagc cactaggact tggtcaatga cctgcccaat
     1801 cagaataggt aggtaaattg ataagccaac ttgagcaata gttcctagaa aggctaggaa
     1861 aaggaggaaa ggatggcttg ctaaatctac ggctaaacgt ttgagcgtct ggtttacagt
     1921 ttgtcgtttc attctagtcc tcctttccat gttgggatgc attgatttca caatagactt
     1981 ggctggattt catcaagtca tcgtgcttgc caacagctag caactcacct ttttccaaga
     2041 ggagaatctg gtccgccatc tgtaaagttg aggttcgttg agagatcaaa attaagctcg
     2101 tgtttggaaa attttctcta atagctttca agagcttgga ctctgtaatg gtatccagtg
     2161 ccgaggttgc atcatctagg atgagaaacg gagcttggcg caagactgct cgggcgatag
     2221 acaatctttg tttttgtcca cctgagaaat ttcgcccccc tgcctcaact agagcatcca
     2281 agagtccttc cttttcactg acaaaatcct tagcttgcgc aatctccaag gcctgccaga
     2341 gttcctggtc agatacttct tgattgaaac ctagagtcaa gttggaacga atggttcctt
     2401 taaagagttc gaccttttga ggtacatagg caatccaaga ccgccactgc tccaaattaa
     2461 gaggactacg tccattttga taaaggtcaa tgttcccctt gtctactgga taaagtccaa
     2521 gtaagagttg caccaagctt gatttaccag aaccagttcc cccgatgata cctagaattt
     2581 gtccttgagt catatcaaag gaaatgtatc tcagagaagg ctgggccgca tcaggatagg
     2641 taaaagtcaa ttcttggact tgtaaaacct tatctctggt agcttgcttt tgttctaact
     2701 ctgaatggat atcctctgga gcctcaacaa agacttcctc gattcgcttg actgagatat
     2761 aggactggtt gagggaattg atcaacatgg ctagcttgac caattccacc aaaatctgta
     2821 agaggtaatt gataagagca atgagagcac cttgactgag cactcctcct tgaattgaaa
     2881 tatagccttg ccagataata acgagaagag ttccattgac aatcagatag gtcagaggtg
     2941 ttaataaact agaccagaaa cctgtctttt cttgtaatct agcataaact tggttaaggg
     3001 tttgaaaaat ctgtaactct cgtttttctt gaccaaaagc acgaataacc cgcatccctt
     3061 gcaattgctg gcgcgtttcc tgaaccagtt ggtccgtttt ctttctgaga ctactgtaga
     3121 aaggattgac caatcgagat aaccctacaa tgacaatggt caaaatggca accaagacta
     3181 agaaccagaa agtcaactca gctgagattc gataagccat aaaaatggca ccaaaaacga
     3241 taatgggcgc tcgtaaaaag agacgcagga attgattgat accagtctga atctggtagg
     3301 tatccgaagt caagcgagta accaaactag aagttgtcag acggtctctg ctgtcctttg
     3361 gcaaggaaag aatatgacga taaagatcgt ttgtcaattc cttagcaaaa cctactgctg
     3421 cctttgctga gtaaaattga gctatcaagg ccactaaaac gccaattact gcaaagataa
     3481 ggagcaggcc aatctgcatc cagagatgac cttgatctcc ctgaggtaaa gattggtcaa
     3541 caatcccagc aatcaccatg ggaaccaaga gctcaaaaac agcttctaac agcttgaaca
     3601 agggggctaa aattgattcc ttgatgtagg gtttgaagta agataatagg tgtttcataa
     3661 atcccttcta ttcatattct agaaatgaag aaagtgggaa gccccactct ctgttttatt
     3721 tgtttaagta aggcaataga tagccatatc ctgctttttc catctcatcc ttggccacaa
     3781 agcgtaaaga agcagaattg atacagtaac ggaggccgcc taactcccgc ggtccatctg
     3841 tgaaaacatg acccaagtga gcactgcctg aacgagaacg aacttcaatt cgctccattc
     3901 catggctcag atccttgtaa taatgaatca actctttgga aatcggacgg ctaaaacttg
     3961 gccaaccaca acctgaagca aacttatcct tggcaaaaaa gagtggctca cctgtcgtaa
     4021 tatctacata aatcccctct tcaaaggttt ggtcataggc attggtaaat ggagcctctg
     4081 tagcagcttc ttgtgtgaca cgataagact cttcagatag actggccttc aacacctctt
     4141 gactaggctt ttcatagttt gctgcatcaa tcaatggctt atcagcatcg gtcacatcga
     4201 tatgacagta acctgaagga ttcttcctga gatagtcttg gtggtagtct tcagccagaa
     4261 tgtagtggcg taattgctcc acttctactg caatctttcg acccagcatg cgttcctgct
     4321 cctgcaccac tgtgtagata gctggcaaat ctgcttcatc ctgataataa atcccagttc
     4381 gatattggcg gccacggtca ttcccttgtt gattgataga tagaggatcg ataactcgga
     4441 aataataaag taaaatctct ctgagtgaca cttccttctc atcgtaaatc acttggaccg
     4501 tttctgcatg gtctgtttcc ttgatcaact ggtaattggt cgtttcgact tgaccattag
     4561 cgtagccaac actggtttct agcactccag aaatgcgtga aaaatattcc tctaggcccc
     4621 aaaaacaacc acctgctaga taaatttctg ccatctttat ttctccttta tcacgttttt
     4681 aactaatact cttcgaaaat ctcttcaaac cacgttagcg tcaccttacc gtatatatgt
     4741 tactgacgtc gtcagttcta tctgcaacct caaaacagtg tcttgagctg acttcgtcag
     4801 ttctatccac aacctcaaaa cactgttttg agcagcctgc ggctagcttc ctagtttgct
     4861 ctttgatttt cattgagtat aaacttcttt tcacaaaaag gatatgaaac cctctggtca
     4921 agagtttccc catcctatct tctattcttt attttgcttc tacacggaca ccttgggtat
     4981 caactctcaa gtcatgcagt tttcctttga aaggttgctt ttccaattct gccttaattg
     5041 ttggcatctt gtcatgagaa gccagaacca taactgtcgg cccagcacca gaaaggtagg
     5101 ttgcataggc cccattttct ttggtcactt gcttaatcat cgcaaattct cttaccaagt
     5161 cctgacgata gcgctcatgg aagaggtctc cctcgattgc ttgcccagcg gtcaccatgt
     5221 ctcctgccaa caaggcagca accgctacat tggcgataga acttgcagca acagcttcct
     5281 tataagacaa ttttttaggc aagacactac ggctgtcgcg agtacgtaat tcatagtttg
     5341 gaatgtaagc tagaaaatca cactctggaa agtctgctac gatagcagag acttgccctt
     5401 caacagaact tgcaataacg agattaccat aaatggctgg agccacattg tcaggatgcc
     5461 cttcaatctt ggtcgctaac tgcaattttt catggtctga taagttgagt tgacccagtt
     5521 ggttggctag ttcaatccca gcaacgataa ccgagctgga agaacccaaa ccgcgcgcca
     5581 aagggacatc actggtcatt ttcaagcgtc ttggttgcaa gtctggtaca atttgcaaag
     5641 cgattttgag caagagatta cgctcatcat gtggaatcca tttgccaatc tggtgttcaa
     5701 tcagccactc atctcgttct tcgcagacct caatttgaag atacttggtt acagctacac
     5761 cgaccgagtc aaaacctggc ccgatattgg cactggttgc aggtacaata atcttcatct
     5821 tattctccta gcaccttgaa ggtattcaag aggtcgaatt ctgaaacctt cttcaattca
     5881 gctgagacat tttcaagctg ggctttatta atcttgtgtg tgatgataac gacacgcgcc
     5941 ttgtcaccct ctttgccatc ttgaaggatt tgcttaaagg aaatatcttg agcattgaag
     6001 atttcagcca acttcaagac ctgacctttt gagtctagag ccaagattga gaaatagtag
     6061 tttgctttga catcttcagg atttgccaag accaagtcac ggctatattc gttgaagtct
     6121 ttgccaatag taccatcatt caaacgacga acgatacgga caatatcagc tacaacactt
     6181 gttgcagttg gtttttgacc cgcacctggt ccgtagtaca tagactcacc aataccaata
     6241 gattctacaa agacagcgtt cattacgcca ttcacactag caagtgggtg cgctttaggt
     6301 aggaaggttg gagtcacttc tgcagcaata cctgaagaag tttcctcaat agaaccaacc
     6361 aatttcacta cgtaaccaag ctcttgagct acagctacgt cttctggtgt gatattgcgg
     6421 attcccttgt gggctacatc atcaaaggca atcttcatgc caaaggcaaa ttgactcaaa
     6481 ataaccatct tgtaggctgc atcaatccca tctacgtcat tcgtcggatc gctttctgca
     6541 aatcctagac gttgtgcttc cgcaagagca tcatcgtaag accagccttc ttccaccatc
     6601 ttggtcacca tgaagttgga agttccgttg actactccaa gcacgcgcgt aattttatca
     6661 gaagccaagg aatttgctaa agtacgaaga attggaatcc caccagcaac tgctgcttcg
     6721 tagtaaagtg ctaccttgtt agcttgagcg atttctagca attctgcgcc atggacagct
     6781 aaaaggtcct tgttagcagt aacaacgtgt tttccagctt ccaaggcacg agtgataaag
     6841 gttttagcag gctcaatacg ccccatcaat tccactacga tagtaatatc ctggtctgat
     6901 aaaatatcat ccacattggt tacaaagtta aagtcattcc ctgctgcaag caagcgattt
     6961 ttttcatctt catccttgac caatacctta gcaactttga tatctgaatg tgctgattga
     7021 ttgatttttc ctccattttc ctttaggagg aaaggcacac cacttgcaac ggtaccaaat
     7081 cctagtaaag caattttaac tgtcatcttt atctcctcga aattttctaa tatagccatt
     7141 ataacagaat tttgtgaaaa ttcctattat agtaaatcac tatttcagta taaaaagaaa
     7201 aaacgaatca gacgattcgc tcttcttaaa atctgaaaat agctttccag aaaggattag
     7261 ccgatttttt gcagattgag cactgcatcg tgactcatca agacttgacc atactcttgt
     7321 aagactgagc gactgatatc actatcgtct gcaaactcgc gcatacgggc caacagccaa
     7381 gctggatatg ggcttggatg attttcaata tccactaaaa tggtcaaata atagcgctcg
     7441 ttcattttgt agagttcaga agtttccatt tcaaaagtca ctgtcttggc aaaaactacc
     7501 aagtcagcca acttagcaaa agaaaggatg tagtagatgt aaggttcttt cttactctca
     7561 gcttcttgtt cagcctgctc ttgctcttct tccttggctt caacttgctc aagagattga
     7621 atggcttcga tatcatcctt ggttttgtct gcgatgcttt tttccagggt tttgataaat
     7681 tcatctggag acatttgagc caattcttcc atatctggca aatccgataa gtcttcaaaa
     7741 tctagatttt ggtcaatctt tgacttggtc acaaagacat ctaccttatc aggttttgga
     7801 gtcacacgga agctcaacat gcctgtatcc agaaagctat caggcatctc tagttcatcc
     7861 aagatagcat aaaagaactc ttctgttttt tcttgaggaa cgagaaagtc agcaatctcc
     7921 attccacgat ccatcaaatc ctctaaagac atcgtgattt ttaaagttgt atcactaatt
     7981 tgtttcattt tcattgctag taacctcata ctttcagttc tatctattat actagatttt
     8041 tacgatttta tcaaaagaag gctcctctat acggatagat tttccctagg gtctttctat
     8101 aggagactcc aaaagaaaat ttctgcagac agatagaaaa agccttcaaa atcagctctt
     8161 agccgatttt gaagacctta tacatcagaa tacttataat ttaaaggttg ctacaccaag
     8221 gatagaacga tttaagtttc tgagaatttg aagactttgc tcaaatttct tataacgagt
     8281 cactccgtac tcttcaacaa gaaggactgt atctctttcc aaaagagatg atacatcctg
     8341 taaatctaca aaatgcattc cttttaaagc ttcttgactc tgtttcaatt tatctaggat
     8401 agctttattt gagctaacga tggtcaattc ctgtccagta tttttgtatg acaaaacatc
     8461 tgctaggtta gcaattgttg taatctctgt tacaaaatca atttgatact gagaaaaatc
     8521 acctactcta ttgattgttg gattaaagag ataaactaac acatttccca tcacaaccaa
     8581 aatcacacaa accactccaa taacaactaa acgaagaatc agatttttca catttaagcc
     8641 aagcgctgtt tcaccatttg cgttcaattc tttagagttg atggtttcca gtttttcaat
     8701 tttcacattt gcataggcat gtttaaattt ctcaatcaac ccatcaattt ttttctctaa
     8761 caagtcattg gcatctttac ttgatgtcaa aattttcaca ccaacccctg catcgtcaat
     8821 catatagtag acggtcaatt ttttccacca atagtcattc gttgaatttt tcaaggttgt
     8881 ttctgtcgtg tctaattcac tggcaatttt tttcaactca ctgggttcta catcattgaa
     8941 aagataagct ccattcaaat taccatcaat caatttccca taaaaatcac tataaccacc
     9001 aatttgatga ttcaaaatcg ttttggccga ctcttttgga ggagtgattt tatagataag
     9061 ataagttgaa taacttgttg tatctttgac agtgttttta ttcctaactg ctttaattgt
     9121 aaatggtaca gcaatgagag caaataaagc gatgagagct aaaatatttg cttttcgctt
     9181 tttataaaga tttgcaaaca aatcagctac tgaataatgt tcaaacatga tttttttctc
     9241 ctttgtttag tagatactag ttttcctttg taagcatttt tgctacaaat ataatcacaa
     9301 gaacaattcc ccagaattgc attgtaaata aattgaagaa actttctgaa aagctgcttc
     9361 ttggcataaa gaatagatta ttcaagatga gtagggataa agcaaatagg attgtccttg
     9421 agcgataggc tacttgcagc atggctataa ataatacgcc gagtaagaaa ctaagcagaa
     9481 agactccaat cataccatag tcggtataca actccatgat ataactactt ccgataccat
     9541 gccctttcaa gtattccttg ttcaagacaa gataggatag attgtgggca taactattac
     9601 tatcaatagc tagttccaca ctattggttg tatgttcaaa ggcttttcct ccgaaaatgg
     9661 ctcccaaact cccccttgca aaataatcaa gaacaggacc aaaagtaaaa ttacggaaat
     9721 ctcggtaagg gaggctactg ttaaatagaa aacctcgagc cagaacacca aaactagttc
     9781 cttgtttata gataaagtca agtaagatat cccagaaacc tgtatgggaa acttggacat
     9841 tatcccgtac ataattaagt actcccatcg ctaacatgag aataggagaa cctacaaaaa
     9901 tcgctaactt ttctttaaac ccaatccatt ttcctttttc agtttgctcc cgcataaagt
     9961 aataaacaaa agcaaataaa atacttaaaa taaagggatt tcgtgtccca attgccaaat
    10021 gaatagtatt agctgcaata aaggagacaa gcactgctgt ggcctgcaat ttctttggct
    10081 tggttgccag atacatacac attgcataga ccgtaaaggt agacaaaatg taggtaaaat
    10141 aaggcagttt actttcaaaa tttgcatagt aggcatagta ggaagtctgc aaacgataca
    10201 agagccgttc aaataaccga atgaaataga aaggataggt tagaagaaaa actcctagtg
    10261 atacaaagcg taaccgcttg atataaacct cttttagaga atttcctata tttgctactt
    10321 ttattttctt cctagctatg aagtaacgag ccagaatgcc tcctgtggtc aagcccagaa
    10381 tcgaaaccat gacaactata aaggcaaaac gataggctat tggatgatag gtatccaaag
    10441 caccatccct aaaataatca atggtcggtc ttgataccag aaatacaaaa atggttaaat
    10501 agaaaataaa atggattaag taatacttga tatcattcca acaagcaatc aagctactaa
    10561 ccaacaagaa caataaagta gaaagtaagc taacattatt attattaaac agatacacaa
    10621 ttccacttac tagcgtcaag gcataactga ctatggtcaa actaaataat aatcgtttcc
    10681 catcaatcac ttggtcaccc ccgttctaat gtaatttttt agatttttca atatttttca
    10741 gtaataagaa tcgatataag gaaatattta tgaatagggc caaagcacta attcttctcc
    10801 ccttacggaa aattggattc ctagaaatag caaaggcatg gccttttaaa aaacgatgaa
    10861 tctgagaata ggcttcaaac tgtttatact gatcatctag caacatctta tccagaataa
    10921 agaagtgggc ataggccaat ctgaaaaaag cgacctcttt caagtcagga tagtttttca
    10981 caacttcatt ataaaacttt tggtagatat caatataggc taaatccttc tctgcatagg
    11041 gtttggtcgt aatactatcc cctctatgga aatagtaata atagggttta gtattaacca
    11101 catacttctt ggccaacttg attaaatcaa aatggtaata ggcatcttcg taaatcaacc
    11161 ccttaggaaa ggataggtca gttgcaatct gtctcttgat tagcttattg caaatcgtcc
    11221 caggtatttt ttcacctatg aggtattcct ttagaaatgt ttgagaatca cagacaaaat
    11281 agtcatcctg attggctgac tgtgggcttt catcattagc atagacattc atgacaccac
    11341 agctcgaaac atccgcatct tcttgaacta attgctcata taagctctga atcatttctg
    11401 gatggatata atcatctgag tcaataaaaa tcagataatc cccgtgagcc tgcttcatcc
    11461 catcatttcg tgcttgcgac aatccttcgt tctttttatg aagcactgac accctgtcat
    11521 cttgttcagc gattgaatca cacaagcgac cactttcatc tgttgcacca tcatcaacaa
    11581 gaataatttc cagattttga taggtctgct tctgaatgga agctatcgat ttttctaggt
    11641 actgcgccac attatagact ggcacaatca cactaattaa tgcagtttcc atgctactcc
    11701 tctaatagtt tttctacttg ttcgatttgt tttgtaattg taaattgttg aatgaattgg
    11761 ctagcctcat cgacatcaaa gtttgaggca gaagtcatgt aattagtaat cgcctgagct
    11821 gcctcttgat tgctctcaat gatttgtcca aatcgtcctt cttgggataa ttcctcagcc
    11881 cctccaacgt ccgtagagat aaaagggagt cccagactca aggcctccac atacactcca
    11941 ggaaaacctt cttgtttaga catagacaaa agaactttcg tctgagatag atactgataa
    12001 ggattttttt gataaccaag gaaatgtaca tagtcctcaa tcccatactc tttgactcgt
    12061 tttttcagtt cctcttccat atcaccagcc ccgataaaat agagatgata gttttttccc
    12121 tcttggtgta ataatcgtat cacttccact acacggtcag aacccttatt ttcctcaatc
    12181 cgtccgatag tacagatact ttgaggagca atctcgatat cgatcttctc ttgagatttt
    12241 tctagaatag tctgaaaatc atatccattg tagattgtct gtaatttaga agtataatct
    12301 ggataaactt ccttgataga attgctggtc ttttttgaaa tccctacaat tgtattcgca
    12361 gcatccaact ggcttctatg tgattctctt ttagagctat ccttaagaag ttcttcaata
    12421 cttccatgaa tccaagatat cttcttgact tctcttcttt tagagaacaa cagtggtgga
    12481 ttcataatgg taaaagaaac ttcaacatca taatcatctt ttacaagcaa acgacgagcc
    12541 agtcttggaa aataaattct cattctccac aaaaaagctc gtaaccatct ggtttggcga
    12601 taatcttgaa gggattttaa aatgcgtaca tgctttggaa cagattcata tcccttgtca
    12661 aagtgctcca tttcaagaat atcaatatca tacttttctg gatccagatt tgaaacaatg
    12721 gttgatagaa tcttctctgc accacctcca agagaaaaag accacataaa aaataagatt
    12781 tttttcttag ccaccatatt ctcccttgta ttctgtataa gacttatcca tatcagcgat
    12841 gacagcatca tgatgcggta cctgcttgtc tgctggtgga ggcgtcatat aatccccaaa
    12901 agcagttctg agatagacat catagccgat tggaataggc atctctgttc cttcaaatgg
    12961 caagaaaaga ttgtcttcaa aagatgtgat tgggtacttg tttctcatgt agccaggacc
    13021 tgagcataat tctgtaatgc catcacaatc agccaaatca tacttagtca tttctttctc
    13081 agcttttttc cagatgcgat aacagagaga ttttggagtc aaacccagta aaatgcgact
    13141 tccccatttc atgagagcac catgcttttc tggaatagtt tgcgcacaaa agagtgaata
    13201 aatcaaggcc caacgaacct gttttttccg ctcagctgga tttttcggat aataatccaa
    13261 aggcaaaaca tccaaggcca gaccatgtgg caaatccaaa tcctgctgat aaggcttgat
    13321 acaggtggtt tccttgtcac gaatggtaat aaaaagatta cgatcaacaa aatccttgtg
    13381 actctttgac aagaaataac gttcatctgc ataacgaggc cataattctg ctaatttctc
    13441 ataatcttta cgaggcataa aaaagtctag gtcgtcgtcc caaggaataa atcccttgtt
    13501 tcgaagggca ccaatagcgc ctccgccaca gagataacag agcaaatcat gttctttaca
    13561 aaaggccaca aaatattcag ccatctccag actacgagcc tgaattgctt ttaaatcagt
    13621 catattgttc attattcttt ctatcgtatc gtttcattat accacaaaca aggggtgaaa
    13681 atctattgca gactgtaaaa aatcaaagcc tgactgctat ccaaatagct atcaaacttt
    13741 gatttttctg tcttatactc ttcgaaaatc tcttcaaacc acgtcagctt caccttgccg
    13801 taggtatagg taactgactt cgtcagtctt atctacaacc tcaaaactgt gtttttagca
    13861 gcctgcggct agcttcctag tttgcacttt gattttcatt gagtattatc ttatctcaag
    13921 cccatttgag cgagcttggt ttgatatttg ttttgatcaa ccagcaagcc caagcctcca
    13981 taaacatcat aggcatctac ccagtcaccc agttctggaa tcgtcaattt ttcaatacca
    14041 ttttttgctc catccaaaac agataaaccg tttgttagga ggaaagtata gggtacgttg
    14101 gttgaggtca tagcaaaaac ctttccaaga gcttcagaac cagtgaaaag tttagtggga
    14161 tctttaattt gctctaaaat tgctgttaaa acttgttgct gtctttttgt acggccgtaa
    14221 tctgcctcat catcatcacg gaaacgagca taattgagca gggtcgagcc attcatctgc
    14281 tgttttccga ctttaatggt ttgggttgga gactcagtct cggtagcgta taaatcatct
    14341 ccgactgtag cttctgttag gggacgccca ttcaatgttg aaaattgagc atcaatcgtc
    14401 accccatcag ggaaaagcgt gtcaatcgct gtggcaaagg cctggaaatc aaccaaggcg
    14461 tagtacttaa tgtccaagtc aaaattatct ttcaagactt ggcgaaccat ttctgcccct
    14521 ttttgcccct cttgttctcc taactcgtag gctacgttta acttgttatc tgtctgtttt
    14581 ctaccgttaa tcacttgact ataaccatct atatagacca aattatcacg catgaaactg
    14641 actagcttca ttttcttatc tgagcccccg acatttaata ccataataga gtcagttcgt
    14701 gtctcaacac tgttctggcc gattcgacca tcagtaccca tgattaaaat attaactcca
    14761 tctctagtgt cctgaccatt aaagacttct acttgagctg cccgagcatc agcagttttc
    14821 tttgcgctag catcttggta accacgcaaa aacatgaata ccatggccaa agccacacag
    14881 accaaaagtg aaaaaatcac cataaaaatt cgtttaagac ggagcttccg tcttttcttt
    14941 tttggagggg aagagagtgc ttgtgatttg gattgtgagc gactccggtt cgcatagctt
    15001 ggtaagtcaa cctgctcttc tctttcttgt tccaagctag agctactatt tcccctagca
    15061 agagttagct tttcttgcaa ataggcaaac tcattttttt ctctctcatt gagatagtga
    15121 atatttttta gcaaataatc ataacgcaac tgctcatgat gacttaaggg attttcttta
    15181 ctcatcttct ctcctttcca tggtctgata ttggataaat aggataggca cccagaattt
    15241 tatactggat tccaatcgct tctaattctt tttgggcaaa gtggaccaag tccttatcgg
    15301 tataatccac atcgataatg aaaaagtatt cacccagtgc tgtcttgagt ggacgacttt
    15361 caatttttgt caagtcaatt cctcgccaag caaaggtcga cagggcctta taaagtgcac
    15421 ctggaaggtt gtcaggtaat gtcaaggcca aactcatctt ttcagtttgt gcttgcaagg
    15481 gaatactagg attttcagct cctagaaccc agaaacgtgt gaaattggct tccatttcct
    15541 gaatatcctc ggcaatcagt tccaatccat attcttcagc agaacttcta ggtgcaactg
    15601 ctgcaaaggg ctggtctgga tgttcggaaa taaaacgggc cgcataagct gtactagctg
    15661 ttacctcgat ttgagcctct ggatattgtt catcgatgaa tttctttcct tgagccaagg
    15721 cctgtggatg tgaaaaaatc ttttcaatct tagtatggcc tggaaccacc atcaactgct
    15781 gatgaatagg ctgaacgatt tctgctactg cttggatgtg agcctgatga aaaagatagt
    15841 ccaaggtttc atgaacacta ccctcaatag aattttcaac tggcaccaca gaatagttca
    15901 ctaatccttg ctcataagcc ttgatgacat ctgtaatgtt ggcaaaagcc tgcaattcct
    15961 catgaggaaa agctgtctgc acaacgtggt gtgaaaatga tcccttggga cctagataag
    16021 caattttcat cttagttcct ctataatttc ctctgggctt agcttggtca catccaaaac
    16081 ccgactagcc acttcctcat accaagcctg tctttcttga aaaatagcta ctagttcttc
    16141 cttgctatta tttagaaaaa gcggtcgctg attgtcctta tcagctacga tacgtaggta
    16201 gagggtttca aaatctgctt tcaggtagat gttatctgta ttagtcttga gtaagtcacg
    16261 atttctctga gaaataacca ctcctcctcc agttgacacg acttggtctg tttgtagtaa
    16321 atcagctagg acttctgatt ctacctgacg aaaggctgct tctccctttt cagcgaaaaa
    16381 attcgcaatg gacataccta ggcgcttctc aatcagagca tccatatcaa ggtaattagg
    16441 gtccaagcct cttgcaatag tcgattttcc agcccccata aaccctaata acaccttagc
    16501 catgaatcaa gctctccaaa tcatcaaaga aactaggata gctggtattg atggcttctg
    16561 cacggtcaag ctccacctct ccatctgcaa ccaagagggc tgcgatagct gtcatcatgc
    16621 cgatacggtg gtcaccaaac gtattgactc tagcaccgtg aagagctgat ttccctttga
    16681 taatcatccc atctgccgta ggagtaatat ctgctcccat actatttaag gcgtctgcca
    16741 caacctgaat acggtctgtt tccttgacct tgagctcctc agcatccttg ataactgtta
    16801 caccttgggc ttgagtcgca agcagggcaa taatgggcaa ttcatcaatc aatcgtggaa
    16861 tcaaagcgcc accaatctct gttcctttca agtcagaaga ctcaacagtc aaggtagaag
    16921 atttagcgac tggatcgatt tcagttattt ccaattttcc acccatggca cgaatgacat
    16981 caataatacc ggtgcgagtt tcgttgatcc ccacattctg cagcactaga cgagaatttg
    17041 gaacaatcaa acctgcgact aaccaaaagg ctgcactgga aatatctcct ggtacgacca
    17101 ccttctgtcc tgtcaatttt tgtggccctt ggactgtgat tttcttactg tccacactta
    17161 aatgaccacc aaattgtttc aacatatctt cagtatgatt acgggtgcac tctttttcga
    17221 taataactga cgccccctta gcttgtaagg ctgcaaacat caaggctgac ttgacttggg
    17281 cagaggcaat tggcaactca taatgaatag gtcttaggtt tttcgtccct tttaagcgaa
    17341 ggggaggcaa gtctcgttca gtttgccctg aaatgctgac gcccattttt ttcagtggaa
    17401 gggtcacacg gtccatagga cgtttggaaa gactatcatc tccaaacatc tctacttcga
    17461 aatctgcacc agcaaggaca cctgaaatca ggcgaatcga ggtgccagaa tttcccatat
    17521 taagggcatt ttgcggcgct tttaagccag ccatgcctac accttgaatg gtaataaccc
    17581 catctttatc ctcaatttca acaccaaggt cacgaaaaac ctgcatggtc gaaagaacgt
    17641 cttcacctcg tagaatatca taaaccttgg tctcaccctc agccaaactt ccaaagataa
    17701 tggaacggtg gctgatagac ttgtcacctg ggacgcggat actaccatgt aaatggcgaa
    17761 tgtttgtttt tagtttcata ctggacctca tacttgcaat acttttacct attttatcat
    17821 aaaaagtcag aaattcctta aaaattcctg actttaggat cgttcttttc ttatttcagc
    17881 aattctgaaa ctggttcaaa aacaattttt tcaatgtcag aaaggtaaat ggccaattgt
    17941 tgttgcttgg taaagaattc tgacaagagg ctatttcctt gaatctgttt accaaagcct
    18001 tccatcttag cttggaagga cgcatctggc atttgacctg tctgtgctag tttttgaatt
    18061 tcctcttgaa aggcaagata ttctgtaaag attttgcttg cctcagcatc tgctgcaatc
    18121 gcatctttag ctgctttaac agccttgtat tctggtaatc cgcgtagacc gcgactgagt
    18181 tcgtttgcac tatcgtaaat atttgacatg ttcttctcct tatttgatga cgactgtata
    18241 gtcggtattt tctgttatga gatgctcagc tctttccaag tcttgagcat ttttaaatga
    18301 aatttgtagg attccgtgaa tatcctcacg attttcctcg ttgatgtgga tgttaaccaa
    18361 ggaagttcca cgtagcagtt ccaaaatccg caggatgaca tcttcttcat caggaacgtc
    18421 aacatagagg tcgtaagagc tatccacacc accacgctta tggatttcca tggtctggcg
    18481 ttgttcacgc gcttggttaa aaaagttcca aatttgctct tcatctccct tactaatggc
    18541 ctgaccaatc acttccaaac gttccttgaa atcctcaatt ctatccagaa tggtctcgct
    18601 attggacaag agaatggagg tccacattcc tggctcgctt tccgcaattc gggtcatatc
    18661 tcgaaaacca cctgccgcaa agcgccttgc catctcatgc tcttgagcat agaccgcagt
    18721 ctgctccatg agactagaag ccaaaatatg aggaaaatgg ctaatctgag aagtgacacg
    18781 atcatgctcc ttggcatcaa tctcgataaa acgagcatga agacctgaaa gcagatcctt
    18841 catttcctta agcgtgtcct gacttgtcag gcttgaaggt gtaaagatat aataggcatt
    18901 ttcaaaaaga ttgacatctg ccgaagcagc ccctgtcttg tgactaccag ccatgggatg
    18961 ggccccgaca aagcgaacag acttgccagc caaatactgc tccgccgcat ccacaatggt
    19021 tgacttggtc gaaccagcat ctgaaataat aacgccttct cgcaaatcca aattggccaa
    19081 ctccttaatg aaagcaatag tttgtttgat tggcaagctg aggataatga catctgccaa
    19141 aggagcaaaa ctagcaaaat catccgttgc acggtcaatc ataccttctt tcaaggcgat
    19201 atctctcgaa gcttgactac gattataacc taaaatttca taatctggat gatcgcgttt
    19261 gataccaagt gccatagagg ctccaatcaa cccaagacct gcgatataga ttgtttttgc
    19321 cataggaact ccttaatagt tctttgtata gtctcggtgt ttggctaccg cttcttttag
    19381 ttcctcaaga ttatctgatg agaatttttc gaggatttct tgcgccagaa ccgttgctac
    19441 aactgcttcc atgaccattc ctgcagctgg aagagcagtc ggatcacttc tctccacggt
    19501 tgccttgtaa ggttcgtggg tttcgatatc cacactcata agaggtttat aaagagtagg
    19561 aatgggtttc atgaccccac gaacaacgat gggttgccca ttagtcatac caccttcaaa
    19621 accacctaga ttattggtac ggcgagtata accgtcttct ttagaccaga gaatttcatc
    19681 cataacttgg ctgcctttac gataaccagc ctcaaagcca agaccaaatt ccaccccttt
    19741 aaaggcattg atagagacaa cagcttgagc caatcttgca tccaattttc tatcccattg
    19801 gacataggaa ccaagaccaa ctggaactcc tccgacgact gtctccacaa ccccaccgat
    19861 ggtatcacca tcacgtttga tttggtcaat atagtccttg atttcctgtt ctcgttcttg
    19921 gttgacaata gaaacttcag actgggcagc tctttgctta atttcagcga ctgtcagatt
    19981 ttcaggaaca tctatttcct taccaccaaa gaccacgaca tggttggcaa tctccatatc
    20041 cagctcagcc aagaggcgtt tggctactgc accaactgcc acccgcatgg tggtttcacg
    20101 agctgatgaa cgctccaaag aatttcgcaa atcatcaaaa cggtacttaa tccccccaac
    20161 caaatcggca tgacctgggc gaggatgagt aattttccgc ttgcttttaa ggcggtcttc
    20221 aatgtcctcc gcagacatga tgtccagcca tttctggtgg tccttattga tgacatccat
    20281 agtaataggc gcccctgtcg tcttcccgtg gcgaacaccc gaagtaaaga caacctggtc
    20341 actctcaatc ttcatacgac caccacgacc gtagccaccc tgacggcgtc taagatcctc
    20401 attgatatcc tcagctgtca atggaagtcc agctggaatt ccctcaataa tagctgttag
    20461 acgggggccg tgtgattctc ctgcagttaa atatctcata cactctcctt attttaccaa
    20521 gtagtctttc atctcttcca gagaaactgg gtgaatggtc gctgaaccaa gctctggcac
    20581 caagaccaat ttcaaggtgt taccacgcgc tttcttgtca tgagtaagag cctgataaag
    20641 cttgtcaact ttccaatttt catagtcaac aggcaagccg aatttctgac acatctctgt
    20701 gatagattgg gtaatgccag ctggcatgag gcctttttcc tcagcaacct tggaaatctg
    20761 taccattccc atggcaacag cctctccatg catgaccttg ccataaccgg cagtcgcttc
    20821 gatggcatgg ccaatagtgt ggccaaaatt gaggtaaaga cgaataccat tgtccaactc
    20881 atcttcaacc accatcttgc gcttcacctg acaagaatgt tcaatcaagg tctctgcatg
    20941 ttccaaaata ctctcaacag aaccattcag tcccgtcaag agagcccaca gttctggatc
    21001 ctcaatcaag ccatacttga taacttcacc catcccttca atcaactctc tttttccgag
    21061 ggtttcaaga acaagtggat caatcagaac cccatctggt tgggcaaagg tccccaccat
    21121 atttttagca aatggtgtgt taacgcctgt ctttccaccg atagaagaat caacctgagc
    21181 tgtcaaacta gtcggaatct gaacaaagtg aataccccgc atataggtag aggctacaaa
    21241 gccagccagg tccccaacaa cgccaccacc aagagcaacg attccatcgc tacgagtcag
    21301 accttgcttg actagaaatt catagacttt ctgaacagta gttaaattct ttctttcttc
    21361 accttctaag aaatcaaaaa cagctacctg aaaaccagca tcttctaggc tgagcttgac
    21421 cttctctgca tagagagagg ctacatggtt atctgtcaca atgactacct tttgcggttg
    21481 ccagagttct cgcaaccact gaccagcctg ggccatacaa cctttttcaa tctgaatatc
    21541 ataaggatga tgaggaatat cgattctgat tttcatagga gagtctccct ttctttattg
    21601 gtatttttct gttaaagact gccaaatctc ttctgtcggc atttccttgc ctgtccacag
    21661 ttgaaaagct tctgcagctt gatagagcaa cattcccaga ccattgactg ctggattgcc
    21721 ctgacttcta gcccatttca aaaacggtgt ttcaaagggt tggtatatga tatctgcaac
    21781 taaaagagtt tctggtaaga ctatgttttc aggaacagga gaggattggc catccatgcc
    21841 cacactggtg gcattaacta gcaaatccga ctcggcaatc cttgcttgca gttcagaaac
    21901 atattctaaa gcacacaaat ccactttaaa gcctgtctgc tcctgtaact tgtctaggta
    21961 aggtcttgtt ttttccatag aaacggaacg aacaaagacc gaaatctgac tgacgccatc
    22021 caaaatagcc tgtgccaaga ttgatttagc cgcaccacct gcacccagca gggtcatctt
    22081 tttacctgaa attgtaaaag aaggcaagca cttaaaaaat cccttgccat ctgtattata
    22141 tccaattaaa ttgccattct cattgacaac cgtattaacc gcaccaatca agcgcgcttc
    22201 atcgctcagc ttatccaaat aaggaatcac ctgctcctta tagggcatgg acagattgat
    22261 gccaaacatc tggtagcgac gaatattggc cactgtttct accaagtcac tcgcttcaat
    22321 ctcccaagcc acataagcac cgttggtagc tgtcgcctca aaggctctat tgtggatgaa
    22381 gggagaaata gaatgcttaa taggattggc aacaactgca gctaaacgtg tatagccatc
    22441 aagcttcatc caaaatctcc ctgatttttt tcatgctagc tagagaaatc tgcccagggg
    22501 cactaacctc atccagactg gcaaaagacc aactcgaacc agtcacatcc gcagtgatac
    22561 gagagacctt gcccacctta cccatagaaa tggtcacata ttcctgttca ggattgaggg
    22621 ttttaaagcc tcgtgtatag ttcatcaagt ctaagacatc ctgctccgtg tgagccatca
    22681 ccgcaacctt aacaagtttt ggatttagga tcgtcaactc tgacaagatt tccatcatgt
    22741 tctcaggtgt ttcttggaaa ttatggtaac tcaaaacaag atttgggaag tccagcattt
    22801 cctcaaaaac atccttgtag ctatagtact caaaatcaat atagtctggt tgatagaatt
    22861 gcgcaacttc cttgattaga tggatatact cttctggaga aaggtcgatt tctccacctt
    22921 cggagcgagt tcgtagcgtg aaaaccaact cacggcctgc gaatttttca aaaatggctg
    22981 gagctacctg caaaatcgct tctttaggca gatagtcggc acgccattca atgatgtcgg
    23041 catccaggta cctcgtggca tccagagcct gagcctcctc taaacttctt ggcattactg
    23101 aaacgattaa tttcatttac taaccttcat actaatcacc ttgaggtaat tactactttc
    23161 atctttttta ttataggcaa aatctgctgg aagaccatat ttgtttaaaa tctggtaact
    23221 tcttcctgca aaacctttat caatttgttc tgtaaatttc tgacgggaaa cattggcagc
    23281 attggtactg gcaatgataa tccctcccgg atttaaaatc tcaagactct gggaaatcaa
    23341 cttgtgataa tccttggcca cagagaaagt ttgtttttta ttccgagcaa agctaggcgg
    23401 atctaggaca atcacatcgt aggtcaagtc tttgcgtttg gcatatttga aatactcaaa
    23461 gacatccatg actataaaac gatgctcgtc tgtgctgagc ccatttgcct gaaaatgcgc
    23521 ttgagacaat tctcgtgaac gtttggctag atcaacagaa gttgtctggc tagctcctcc
    23581 catggccgca gctactgaaa aagccgctgt gtaggaaaac atattgagca aggatttacc
    23641 catagccaag ccgtcaacta aactaccgcg aacctcatgc tggtctagga aaattcctgt
    23701 catcaagcca tcattcataa agacttgata caggacacca ttttctaaaa cagtgaaaaa
    23761 gtcaggtgct tcttgaccat aaacatgggc agattcatag tcaaaaccct taaagcggat
    23821 tttctcataa gcccctaaaa cctcagggaa aacctgtcta aaggcttctg atatagtctg
    23881 acgaatctga taaacataag agttatacca agaaaagacg gcgtagtcgc cataaaggtc
    23941 cactgtcaga cccccaaagc catctccctc ttgattaaag agacgaaagg cagttgtcaa
    24001 atcatcttga tagtaggcgt ttctcttttc tttggctttt ctaaacaacg tttcaaagaa
    24061 agtttgattg aaggccacct tgtctttgct gacaaaccag cccaagccct tgttttgctg
    24121 agaaaggtag gcagtcccaa gaaagtttcc ttcctgaccc tgcacctcta cttcctgatc
    24181 cttaagattg acattctcaa gatcactggc ttctagtaaa actagcccct tagcaagctt
    24241 cttttcaacc cttttgctga ctcttattct attcataact accattatat caaactttta
    24301 gacaattctc aaaaaagaaa ctacccttgc ttttttactc ttcttttaaa aaatggtata
    24361 ctagacttcc tgcaaaacta ggaagtaaat gtgtaagaat cacaataaaa aatgctcttc
    24421 cgtcttggag gagcatttct ttttatcaac gaaaatcaaa taacaaacta tgaaactagc
    24481 ctcaggttaa ctgtgagatt ataggtagag aggttgaatc agcaatatgt gtctgtcaaa
    24541 tttagtgaca aaggtagtag aagaaagatg aagaaataaa tctgcttcaa taggtatctg
    24601 gaaaatttga ttttatagag aagccttttg ttacaaactc aatatactat caataaataa
    24661 tattatagaa gcaacaataa ttataatttc acctatctgc atcattctat ttcgaattct
    24721 aaatatatgt tctatcaaga atacttggaa cacacacatt atagtaatta acgtttttga
    24781 aattgaaaaa tatccaaata aataaactat aaacaacaaa aatagaacta tgttatattt
    24841 cttattcaaa acattcctcc ctatattttt gattaccaat cttaatcatt tacaactaca
    24901 ttctaacaaa ctataaaagc gtttgtcgaa ttgaatttat caagcaagcg accaaccagc
    24961 tcatcttttt tctatttctg ccaatatgcg tgacaggtaa taatgatagc caaaaatagc
    25021 aagagcaagc aggaggataa gagctcctac tcccaagctg atggcaagga tagtggagag
    25081 agactgaacc aagaatatgc tcccaattac aagggccatc aggattgcac tataaataaa
    25141 caataaaact atggcgacta tgccatttga acgattcacc aggtccgtaa tgctactcca
    25201 attggttgac agatttttaa cgtccttaaa gtaatggtgg caagaaagga tgacactggc
    25261 aaggatccat gccacaataa ggtaaatcat cgaaatgatg ggcaagccta gatatagaga
    25321 aagaccaagc aaagtcagaa ctggtaaaaa ggactggaca gcatatataa tccaaaattt
    25381 cactttcaca taacgagcaa agtcaaaggg taaactctta agaaaatcaa cattttccct
    25441 ctccaaggac aaggcaattg aatgcaggct ggtgatattg ttattgacaa ctgctataaa
    25501 cactcctaca aaaaacaagg gtaaccagta tggaggatga atgtctggaa ctatctgaga
    25561 atctcggatt ttggaaatca gaccgatcat catgagataa ggaaagaaag cacttgtaaa
    25621 aagcactgta accacgccag taccctgtcc caagagggtg aggtggtagc gtaaaaccat
    25681 gcggaaaaat ccctttttag tggttgaaat tctctccttg ctgcgacgtt cttttttgac
    25741 cttctcctca ctattaagca ggatcacgtc ataaaaacga ggaaggacct tctttttggt
    25801 cagataaagc aggaagagag ttagtcctat ccaagcgagc agacccaata tggcttctgt
    25861 cgaaaaaggc tccactgcta ttttgtaaaa gatatgaaga ggataaagga gaaatggaat
    25921 gtctctaact ttgtcaacaa tacttccaaa agtcgactga agaaagaaga taaatattaa
    25981 aggtatgaga actcctatcc caatcatcac attcgaaaaa atagactgat actttctgaa
    26041 gaccgtagtt tgagccaaga aatgtactgc cactaccatc actaaagtaa cagagacaaa
    26101 taataaggtc aaggacagta gcatcaaagg caaacccaac cacagagaag gtgctagcct
    26161 aatgtagagg accagaaaat aagctaggat tggtacaatt ccagctagag ctggcaagag
    26221 gacagacaga cctttggcca ttataatctc tgattcttta aaggcatagg gcctatagga
    26281 ggccaggtcc ttactctcat aaaagacatt gtaaaatgca gtgaaagaag ttgaaaaggc
    26341 cagcaccagt aaaatagcaa ccatcgagct aaaataaata ggtatttcct caaaaggaaa
    26401 atgaatggct atattactaa aacagatgag catcaagaga ctggaaaaaa tgtaagaact
    26461 taggactcta gcggaaacat ttactttttt cccaggattc ttagcctgct tctttcgtag
    26521 attagccaga ttagcttctt gagatgaata gaggatattg atatcaacta attttttaat
    26581 gaccttgaga cgcatctgaa acctcctctt ttctaccagc aaggctaagg tagatacttt
    26641 ccaaagactg gtctgggttg tcttttctca agtcctctac cttaccacaa taaatcaaat
    26701 gccccttttt caaaatagca atccgatcac agacttgctc agctacctct agcacatgag
    26761 ttgaaaacaa aactgtctta cctttttgcg catgctcctt catcatttgc ttcaaatcaa
    26821 aggcggcctg gggatccaaa ccagtcaagg gttcgtccaa aacccaaata tcaggatcag
    26881 acaagagtgc cccgatgaca aagactttct gacgcattcc atgagaaaga gtttcaataa
    26941 cctgatagcg attttcagca aaatcaaaaa cgttcaatag cctagctaga ctagcctcca
    27001 agtcagatct actcagatca taggatgagg cgatcaattc ccaaaattca ttggccgtta
    27061 agcgtaaaaa taagtcaggc gagtctgcta cgtagccaat ctttcgttta atagccaagc
    27121 gattttccga taactcctga ccgtctacca aaatacgacc actgctgggt gaaatgatac
    27181 tgactaggga ttttatagtg gtcgattttc cagccccatt atgaccaatc aagcccataa
    27241 tctctccatt ttcaatctgc aaattgagat tactcaaggc ctttttatca ccatacaact
    27301 tactaacatt ttgaaattca atcatgggac aactcctatc tttatctgta ttatatatcg
    27361 ctatactagc actttgatac aaaaaaatca atactttatt ttaagtagtt aaaatagttt
    27421 ccttctatct tacgcaaacg tttgcgctaa tagatacttt atgatagaat aaagaacaag
    27481 attgacaagt aagaggaaac attatgcaaa atcaaacact catgcaatac tttgaatggt
    27541 atctgcccca cgacggtcaa cactggacgc gtctggctga aaatgctcca cacctagctc
    27601 atctggggat cagtcacgtc tggatgccac cagccttcaa ggcaaccaac gaaaaagatg
    27661 tcggctatgg ggtctatgac ttatttgact taggagagtt caaccaaaaa gggactgtcc
    27721 gcaccaagta tggtttcaaa gaagactatc ttcaagccat tcaagccctt aaagcgcagg
    27781 gaattcaacc tatggccgat gtggttctca accacaaggc tgctgctgat cacagggaag
    27841 cctttcaagt tattgaagtg gatcctgtag accgtacagt tgaacttgga gaacccttca
    27901 ccatcaatgg ctggactagt tttaccttcg atggtcgcca agatacctac aatgacttcc
    27961 actggcactg gtaccacttc acaggtacag actatgatgc caaacgccgt aagtctggga
    28021 tttatctgat ccaaggggac aacaagggct gggctaacga ggaattggtc gataacgaaa
    28081 acggaaacta cgactacctc atgtatgccg acctagactt taaacatcct gaagtcatcc
    28141 aaaacatcta tgactgggct gattggttca tggaaacgac tggtgtagct ggtttccgtt
    28201 tggatgccgt taagcatatt gactctttct ttatgcgcaa cttcatccgc gatatgaagg
    28261 aaaaatacgg tgacgatttc tatgtttttg gtgaattttg gaacccagac aaggaagcca
    28321 atctggacta tctcgaaaaa acggaagaac actttgacct tgtcgatgtt cgtctccatc
    28381 agaatctctt tgaagccagt caagctggcg caaactatga ccttcgtggc attttcacag
    28441 atagcctggt tgaactcaag cctgacaagg ctgtgacttt tgtcgacaac cacgataccc
    28501 aacgaggaca agcccttgag tctaccgttg aagaatggtt caagccagca gcctatgccc
    28561 tcattttgtt acgccaagac ggccttccat gtgtctttta cggagactac tatgggattt
    28621 caggccagta tgctcaagaa gatttcaaag aaatccttga ccgcctccta gccatccgaa
    28681 aagatttggc ctatggagaa caaaatgact actttgacca tgctaactgt atcggttggg
    28741 tacgttcagg tgctgaaaat caatccccaa tcgcagtcct tatctcaaat gaccaagaaa
    28801 acagcaagtc aatgtttgtc ggtcaagaat ggactaatca aacctttgta gatttacttg
    28861 gtaaccacca aggtcaagtt acaattgatg aggaaggtta tggacaattc cctgtctcag
    28921 ctagatccgt aagtgtctgg gcagtcaata ccatctaata gctcataata accaagctag
    28981 gtccaagcgg atttggcttt tttgtattca caaaaagacc tacccaaatg gatagatctt
    29041 tacttgatta caatttacct gctactgcat ccaacaattc ttggatctta ggttggttgc
    29101 ttcctcctgc catggccatg tctggtttac caccaccacg tccatcgatg attggtgcta
    29161 attctttgac aaggtttcct gcatgaaggt cttttgtctt gcttgctaca aggacattga
    29221 ctttgtcacc gatagcggca actaggacaa gaagatcaga gtagtctttt tgtttccagt
    29281 tatctgcaaa ggtacgaagg gcacctgcat cggatacaga cacttgacta gcaatgtaac
    29341 gatgaccgtt gacttcctta acatctttga agatatcgcc tgcggctgca gctgcggctt
    29401 tttctttcaa ctcagcattt tctttttgaa gttgacgaag ttgttcttga agtccttcta
    29461 ccttgtgagg tacttccttg acttgaggtg ctttcaaggt tgctgcgaca gctttaagag
    29521 catcctcttg ttcacgatag gcttcaaagg cttccttacc agtcactgcc aagatacggc
    29581 gagttcctga accgattcct tcttctttga caattttgaa gagaccaatc tcagaagtgt
    29641 tgccaacatg agtaccacca caaagttcaa tagagtagtc accaatagtc acgacacgaa
    29701 cttccttgcc gtatttctca ccaaagaggg ccatcgctcc catttcttta gcagtgtcaa
    29761 tatccgtttc aactgtctta acttcaagag cttcccagat tttttcgttg acttgctgtt
    29821 caatcgcacg caattcttca gcagttacag cttggaagtg ggtaaagtca aagcgaagga
    29881 attcaacttc gttaagagat cctgcctgtg ttgcgtggtt tccaaggata ttgtgaaggg
    29941 cagcgtgaag caaatgagtc gcagtgtggt ttttcatgac acggtgacgg cgattgctat
    30001 caattgccaa ggtatattct tggttcaagg caagcggtgc aaggacttca actgtatgaa
    30061 gggcttgacc atttggggct ttctgaacat tggtcacagt agccacaacc ttacctgact
    30121 catccaagat ttgtccgtgg tcagcgacct gtccacccat ttcagcatag aatggcgttt
    30181 ccgcaaagat aagtgaggta gttccttctg atacagcttc tacttctgca ttgtcagcaa
    30241 cgatagccac caatttagaa gacaattggc tagcattgtg gttgaagaca ctttctacag
    30301 tgatgttttg aagagtttca ttttgcatac ccattgagcc acccttgaca gctgacgcac
    30361 gcgcgcgttc ttgttgttct ttcatggctg cttcaaaacc ttcacggtct acagtcatac
    30421 cagcctcttc agcaatttct tcagtcaatt caactgggaa tccgtatgta tcatagagtt
    30481 taaagacatc ttgaccagca atgacagatt gacctttttc tttcaagtct gccacaatgc
    30541 cttgggcaaa gtgttgacct gagtgaaggg tacgggcaaa tgattcttct tcgctcttaa
    30601 cgattttctc aataaagtca cgtttctcaa gcacttctgg gtagtagctt tccatgattt
    30661 ttccaacagt tggaacgagt ttgtaaagga aaggctcgtt gatacccaat ttttgaccat
    30721 gcatagaagc acgacggaga agacgacgaa gaacataacc acgaccttca tttcctggaa
    30781 gggcaccatc accgatagca aatgaaagag aacgaatgtg gtctgcgata accttgaagc
    30841 tcatgttgtc gccatcttgg tcataaacct taccagacaa tttctcgact tcacggataa
    30901 tcggcatgaa gaggtccgtt tcaaagttgg tcttagcccc ttggataacg gccaccaaac
    30961 gctccaaacc agcgcccgta tcaatgttct tatgtggtaa ttccttgtat tcgctacgag
    31021 gaacagcagg gtctgcgtta aattgtgaca aaacgatgtt ccagatttcg atgtaacggt
    31081 cgttttcaat atcttctgca agcaggcgaa gaccgatatt ttctgggtca aaggcttccc
    31141 cacggtcaaa gaaaatctct gtatctggtc cagaaggtcc cgcaccaatt tcccagaagt
    31201 tgtcctcaat tggaatcaag tgacttggat ccactcccac ttcaatccag cggttgtaag
    31261 aatctttatc atctggatag taagtcatgt aaagtttctc agctgggaag tcaaaccatt
    31321 cagggcttgt caaaagctca taagcccaag tgatggcttc atcacggaag taatccccga
    31381 tagagaagtt ccccaacatt tcaaacatgg tatggtgacg cgcagtcttc cctacgtttt
    31441 cgatgtcgtt ggtacggata gccttttggg cattggtaat acgtggattt tcagggataa
    31501 tggtcccgtc aaagtatttc ttgagggttg ctaccccaga gttgatccac aaaagagttg
    31561 ggtcatttac aggaaccaaa cttactgatg gttctactga gtgacctttg gtcgcccaga
    31621 aatcaagcca catttggcgt acttgtgcac tagatagttg tttcatattg tctccttatt
    31681 tacttgttta atgtgattgg ctttccagca tttccacata gtcaatcgcg acacagaggg
    31741 aaatgactag gtctgcataa gcgtcttcaa gaaccgttac ggtataggta gaggtcagat
    31801 ggaagagttc cttcttaatt tccgcaatca actgatcgcg atcatccagc aatttgaaat
    31861 tcaaatccca gatattgccc tcgatacgaa gacctagatt atcaaactca tacttatctc
    31921 gccagaaggt caacttctta cgaatgacaa aactcgagcc atcccgaagc tgaatctcaa
    31981 aacgaggaag caaggtcaag atttctttac taatctcact gacttgttca ccagccgcat
    32041 catagatggt aaaggtttta ggaatcttaa aaaatgatcc ctccacctga taggcaattt
    32101 ctcccctgtc atccttgata gcgaagcgtt cgcctccaag acgaaacttt tgtttgacaa
    32161 gaaatgtttt catcaacacc tccaaaaatc aaaagacaag ctcatatcac gaagggcgaa
    32221 aaaccgcggt accaccttca ttcaatgaac ttgtcattct cttgttctta tgcaattgta
    32281 tgattgagta gcatgacttc ctagcttaga tggctcgcag caccgccatt tctctggact
    32341 aagacaagtg aaaatcaatt ctcaactttc ttattataac gtttttttaa gcttgcgtca
    32401 actggaaatg atctccgttg aattagacca attccctaca tctctgatta ctttttcagg
    32461 atatattttt tcttactgcc gtttttcttt ttatcccaaa ttttcatatt actaaacaca
    32521 gctactagaa tatttccaaa tataaaggtg cctatcaccc aatatatgga ctcagttgtt
    32581 aggtattgtc gatccaagcc atcctttaaa tgggatagta taacagtttg gttaacaatc
    32641 ataaaggttg gccagaaact ttttttgaaa aaagtagaca ttttcattat ttgttgccgc
    32701 tttctgtaag gttaatactc aataaaaatc aaaaagcaaa ctaggaagct agcctcaagc
    32761 tgtacttgag tacggcaagg caacgctgac gtggtttgaa gaatataggc ttagtatact
    32821 actaggcaag caaataagca actagaatag aaaaagatag ggttctaaaa actgacttct
    32881 attccttaaa aacgaaccag cttgactgat tcgtcttctt acgtttatct cctacttccg
    32941 atacatttta aactgtagga agaggtcgct atatttccct gtccatttat ggtcaaattt
    33001 ctcataaact tctaggtgtt tcatggtttc aacatctgga tagaaggcct tatcttcctt
    33061 tgtttcctct gggagcaatt ccttcgctgg taggtttggt gttgaatagc cgacatactc
    33121 cgcattttgg agagcgtttt caggtttcaa cataaagttg ataaaggcat aggctgagtc
    33181 ttggttttta actgttttgg gaatgaccat attgtcaaac caaagattgc tggcctctgt
    33241 cggtaccaca taacgtagat tttcattttt ttctaacatt tggctggctt caccagagaa
    33301 ggtcacgccg attgcaacat tattctgaat catgtagccc ttcatctcgt ccgcaacgat
    33361 agccttgata tttggagtca gtttgtagag cttatccact gtctcttcca actgctgcgg
    33421 atccttggag ttgaggctgt agccgaggga attgagtcct agtcccagca cctcacgcgc
    33481 cccatcaaaa agcatgatag aattcttata ctccggcttc caaaggtcat cccaatgctc
    33541 aggcgcttca tctaccatgg tttcgttgta gacaattcct aaggttcccc agaagtaagg
    33601 gatggagaat ttattacctg ggtcaaagga ctggttgaga aactctggtc cgatattttc
    33661 gattccttca atttttgaat aatcaagcgg aaccaagagg tcttcgtcct tcatcttgtt
    33721 aatcatgtat tcacttggaa tggcaatatc gtaggtcgtt ccaccctgct ttatcttagt
    33781 gtacatggct tcgttggagt caaaagtctc gtactgaact tgaattcctg tttcttctgt
    33841 aaactgagtc aagagttcag gatcgatata gtctccccag ttatagataa ccaatttttg
    33901 actatctcga ctattgattt tactatctaa atgagtcgca attccccaca agacaaggat
    33961 aatcgctgca attcctgcta aaaatgaata gatttttttc atgcttgctc ctccttctca
    34021 cgagagataa agtaataacc tacaactagg ataatactaa agagaaagac tagagcagac
    34081 agggcattga tttctaagga aatccccttg cgagcacgag agtaaatctc gactgatagg
    34141 gttgaaaagc catttcctgt tacaaagaag gtcacggcaa agtcatctaa cgaataggtg
    34201 aaggccatga aataaccagt aatgatagac ggagtcaggt aaggaagcat gatttccttg
    34261 aacatctgaa attgactagc tcccaagtca taggccgcat gaatcatgtc gccattcatt
    34321 tccttgagtc gaggcaagac catcaagacc acgataggaa tggagaaggc cacgtgacta
    34381 gatagaacgg tcaaaaagcc aagtgaaaac ttgagttggg taaagagaat caagaagcta
    34441 gcaccaatca taacgtcagg cgcaaccatg aggatattat tgagtgatag aaaggcttct
    34501 tggtatttct tacgagactg gtagatgtaa atggcaccaa aagtcccgat aatggtcgct
    34561 atcaaggctg ataggaaggc caagaaaaat gtctgagcca aaatcagcat gagtctccca
    34621 tctccaaaca tggtttcaaa gtgagtccag ctaaaacctg taaagctatt catatcatca
    34681 ccagcattaa aggcatagcc aatcaagtaa aagataggca ggtagaggac cagaaagacc
    34741 agtcccagat aaaggttggc aaattttttc atcgttctct cctttcctta gtcacccaca
    34801 tggtgatgaa catggtcagg atgagaatca caccgatagt tgaacccata ccatagttgt
    34861 cattggttag aaaattctgc tcaatagccg tccccaaggt gataacgcgg ttcccaccaa
    34921 tcaaacgggt cagcatgaag agactcaaac ttgggataaa gaccgactga accccacttc
    34981 gcacaccgtt catagataga gggaagatga catgacggaa ggtctcccac ttagttgcac
    35041 caaggtcgta actagcattg atgagattat tatccatatc gtctaagaca ttgaaaatcg
    35101 gcaaaatcat aaaggggagc tcgatgtagc ttgcgacaaa gataaatgag aaatcagtaa
    35161 atagcaactg ctgtgaacca attccgataa attccaagaa ttggttaata gagccattct
    35221 gaccaaaaat cccgataaag gcataagcct taagaagaag gttgatccaa gttggcagaa
    35281 taatcagcat aatccagagt tgacggtgtt tgagacgggt caaaaagagg gccgtcggat
    35341 aactgataag cagtgtcaca aaggtcacaa tgcctgcata aagcactgag ttgaaactca
    35401 ttttaagata ggtcaagttt tgtgacgcaa agtaagattt gtaattttct aaactgaact
    35461 ggccttcgat gttgaaaaag gattgaccga aaatcaagac caagggtgcc aatacaaaga
    35521 gggcaatcca aagcatgtag ggtactacaa agagtttaga gcttgttttc ttcatctctt
    35581 tcctcctcga ttgcattgat caaacctgct tcttgctctt cgatttctac gtactcctca
    35641 atacgagcat cgaactcttc ttcggtttca ttgagacgca tgatgtggat gtcttctggt
    35701 tcaaagtcca gaccgatttc ctcacccacg atggccttac gggttgagtg gatcatccat
    35761 tcatttccaa gttcgtcata ggcgataatt tcataatgca ccccacggaa gagctgggta
    35821 tcgaccttaa cttgaagctt gccttcttca ggaagggtaa tgcgcaagtc ctctggacga
    35881 ataacgacct caacaggttc atttggcttc atcccaccat caaccgcttc aaagcgtttg
    35941 ccgttaaatt cgaccaagta gtcctcaatc atggtacctg gcaagatgtt tgactccccg
    36001 ataaaggtgg caacaaagtg gttgattggc tcatcgtaga tgtccacagg ggttccagac
    36061 tggacaatct cgccatcatt cataacgaaa atccagtcac tcatggcaag agcttcttcc
    36121 tgatcgtgag tgacaaagac aaaggtaatg cccaatcgtt gttgcagttc acgcagttcg
    36181 tactgcatgt ctgttcttaa tttcaagtcc agcgctgaca agggctcatc caacaaaacc
    36241 acacggggtt ggttgatgat agcacgggcg atagccacac gctgacgttg tcctccagaa
    36301 agtttgcgga tggaacgttt ttcataacct tccaactgaa ccatcttgag aacttccgct
    36361 acacgttgct cgatttcttt cttatcaatg ttacgcaagc gaagtggaaa ggcaacattt
    36421 tcaaacacat tcatatgtgg gaacaaggca taggattgga agacagtatg tacgtcgcgc
    36481 ttgttggttg gaatatcatt gatacgaaca ccgtctagca tgatatctcc tgtcgtcgca
    36541 tccagtaaac ctgcaataat gtttaggata gttgatttcc ccgaaccaga tgcacctaga
    36601 agggtgtaga atttcccttc ttccaactca aagttgatgt ctttgagaac cttggtgttg
    36661 ctgtcttcaa aaactttaga gacgtttttg aattcgataa ttgatttttt caattggcat
    36721 aaattccttc tttttcatag attaaccgat cggggctctg tcaggtcgcc actacctctt
    36781 gcagggagta aaaccacctg catacatctt cgctaccaat aggctttcac ccccctttcc
    36841 atgacatagc agcagctttt caaatacagc ttcctacttg ctttcaccca agatccggac
    36901 ttctctttca agcgtaatac ctgagtgttc cttgactttt tcgataaccg attggatcaa
    36961 gtcctcgtag tctttggccg ttccatctgc gacattgatc ataaatcctg catgcttttc
    37021 tgacacttct acgccaccga tacgatagcc tttcaagcca gcttctgaaa ttaactgacc
    37081 tgcaaaatgc ccgactggac gcttaaagac cgagccacaa gatgggtatt ccaaaggttg
    37141 cttgagttca cgtaggtgcg tcaagcggtc catttcctgc ttgataacct gatgggttcc
    37201 tggggctagg gcaaatttaa ctgacaagac aactgcacca gactcctgaa tagctgaatg
    37261 gcggtaacca aaagccaagt ctttagcaga cagggtttcg atttctccat ccttggtcaa
    37321 gaccttacaa gactgcaaga tgtgagcaat ctcgccacca taggcacccg cattcataaa
    37381 gacagcaccg ccaacgcttc ctggaatacc acaagcaaac tcaaagccag tcaaactatg
    37441 acggagggca atgcgagttg tttcaatcaa gttagcccca gcttctgctt caatggtata
    37501 gccatcaaca gaaacgttat tgagcttgtc acacaagatg acaaatccac gaatcccacc
    37561 atcacgaacg atgatattgc ttgcattgcc aagaaccatc caagggatat tttcttggtt
    37621 ggcaaatttc acaacgcgag ccaactcaaa acgatttcgt ggaaagacca aataatcagc
    37681 ctctccacct acttttgtat aactatagct atgcaagggt tccttaaaac ggatatcaat
    37741 tccttctaag atttcaagca ttttttctct tacagacatg tcactcttcc ttttacaaaa
    37801 ttcattccat tataccattt ttagagacat ttgacgacca taaaaatacc ttgtttggat
    37861 tttgcataag aaaaagaggt tccccccttt ttatgatttt ttacaaaaga tttccttggt
    37921 tccataggca accagaacga gctccagtgc tagaatcact tcaaccaaga ctggatttgt
    37981 caaccagcct acttggaaaa gagatggtgc cagatcaaag aaggcatgca agccataggc
    38041 tgctaggaga taaatccatt tcttctggcg aacagcttgg taaacccaaa ctgtcaaaag
    38101 taattggaaa ccaagcgcca agattcgctc aaaaccaagc aaataaatct gccagaccga
    38161 aagtgactga atggttttta acatattttc agacagtaat tgcataacct gtggattctg
    38221 agtttgaact gccgaaagaa cgatgtaaag attgagtaaa ctaataaggc ctagaaaaat
    38281 caactccaag ccaccatgcc ctaggccata ggccaaggca tctgcctttt ccaaacttct
    38341 ctttttctcc aaccatttga agaaaacaag acgagccgtt tcctcaaaaa atgctgccat
    38401 ggctaggcca tagataatat agataagcgg atgatcttgc aagagggcaa tactaccgtc
    38461 tttttgagga tgcaaaatca agatatgcac cagtttttcc aaaatctgcg aagagacaaa
    38521 gaaagcgact gcacccaagc ccaagacagc tagattaatc tggtatttct ttttggcaaa
    38581 ccaaatgctt cctatcagaa aagctagcaa cagcaacatg gtaataatga tatgaatggt
    38641 cattttcttc tcctattctg ccttttcaat atcttttttc atctcgtcaa cattgaactt
    38701 agcaaacaag tattgacggt cttggactgg gaaacgttgg tccaactggt caactgctcc
    38761 cacctcgata atgccttcct tgatgacaaa atccatgaca tgtccaccga aggtcaaatc
    38821 atctgatatg aagtgcagat ggtagcctgc cacactgacc ccatggaaaa tctcaggcgt
    38881 ccagaaacca acaatagtcc ccgcaacatt gtcacgacta tattccggtt gatgggttgc
    38941 gacatcagca aacttggtat cgggtgttga cttaggaatc atacgcacat gcatatgtga
    39001 aaattccccc cgaatcttga tagagcggaa aagattttcc ccatcataat aagactcaat
    39061 tcgttctttc aattccttgt ctgtcatctc aaagcgctgg cggaaaatga cctctgcctg
    39121 atgcggtacc actgcagcgt aaggaataag ggcatctggt gacacttccc caatttctgg
    39181 ctggtctcct gaccctttgg cctgataagc cttgccatcc aagacaatca attccccatc
    39241 aatggaatcc aaggttccca aaccaaggtc accatgttct agcaattctc ctactgtcat
    39301 agtaccacca taaaggccag ccatcaaggc tccaagggta ttgtattgaa ataatttcac
    39361 tggttcctgc acgttcttat ccattcactt tcttgtctgt tattctataa atcttactcc
    39421 taagtatacc acatttgccc ctagatgtga acgagagaaa cgctctagac attgccaaga
    39481 aggaaaaaaa aaggtacaat gtaacaaaat caagggaggt ctggaatgaa gaaacaaagc
    39541 aagtacaaag aggtcgtttc ctatctgaaa aatggtatcg agtctggacg atttccgacg
    39601 ggtagtcgcc tgccttctat ccgtcaactg agccttgact ttcactgcag caaggacacc
    39661 attcaacgag ccctgctgga attacggcac gaacaatacc tctatgccaa gcctcagagt
    39721 ggctactatg tattagaaca agggcaacat caagacctag aaatcgaggt taccgacgaa
    39781 catgccagtg cctatgacga tttccgactc tgtgtcaatg aaaccttgat tggccgagaa
    39841 aactacctct tcaactacta tgacaatcaa gaaggattag aagacctaag acagtccatt
    39901 cacaaactcc tctttgagca agctctctac tgcaaggcta accaactagt actgacttct
    39961 ggaacccaac aagccttatt tatcctctct caaatatcct ttcctagaca agccaaggaa
    40021 atcttggtgg aacagccaac ctaccatcgg atgaatcgcc tcttgattgc acaggggctg
    40081 gactatcaaa cgattgaacg aggcattgat gggattgact tggaggagct ggaaggccac
    40141 ttcaaaacag gaaaaattaa atttttctac accattccta gatttcacta tcctctggga
    40201 cattcctatt ctgagcaaga caaacgatct attcttaact tagctgccaa gtatgatgtc
    40261 tatatcgtag aggacgatta tctgggtgat ttggactcca agaagggcca aaccttccac
    40321 tatcttgata cagaggagca tgtcatttat atcaagtcct tctcgaccag cctttttcct
    40381 gcccttcgta ttacagcact cattcttcca aatgctatca aagaagcatt tgtggcctac
    40441 aaaaatatcc tagactacga cagcaacctc attatgcaaa aggccctgtc actctatatt
    40501 gacagtcaat tgtttgaaaa aaatcgtttg gctcgcttga ccaatcatga atcttaccaa
    40561 aaacaaatcg aggaaaggat aactaaaaca ccttgtcccc ttcctcatta tcccctacac
    40621 gatggtttat tgctagacct gagacagtat cctaaaatcg ccagtctcaa acacagtcaa
    40681 ccgggcttgg acttctttga agaggcctat ttaagtacct gtccttatca atttgccaag
    40741 gtgtccctag acaatctgga aaatgtttta aactatttaa aagcagaatt ggaatgacat
    40801 ccaactctgc tttttcttat tcttcaactt cagttagact tgctgctttt tcaagatagc
    40861 tttggtaaat tccttcatcc ttaagttttt ggatgacctt gtctaccact tctttcaaat
    40921 catcactatt ttttctaaga gcaacggcat tggcgtcgcc gtccttcatc ttcaagctga
    40981 cagttgcgac agctaagcca gcgtttttag cagcataact aagtgcaaca ggctcatcca
    41041 tatgaacagc atctactttt ccagcctgca attcattgac tgcttcaccc atattagtta
    41101 gggaagttaa ttgagctttt ggcaattgtt ccttgaccat tgattctgga acagtccctt
    41161 tttgggctgc aatattagca ctttctaggc tagttaaatc cttgtatttt tccacatcag
    41221 ccttacgaac caagaaacta atcttgtttt catagtatgg gattgaaaaa tcaaagactt
    41281 cttttctctc gtcagtagca ctaattcctg caactgctag gtcagcctta ccagtttgaa
    41341 gactggtcaa aacattgtca aaactcatgc ttgagatttc caacttaacc ccaagttcat
    41401 cagcgatagc ctgagccatg tcgatgtctg caccgactac ctggttcttt ccatcaacca
    41461 atgattgaaa ttcaaagggt gcatagtcag gactggttgc cacaactaat ttcccctttt
    41521 gcttaatggc ctcaacagct gactgagaac cattagaacc tgactggcaa gctactaaga
    41581 agaaacttgc aagaaaatta cataaaacaa atatccattt ttttgatttc ataaataaac
    41641 aacctctctg ttaattttgt ataattataa cgatatccaa gttacttgtc aagtgttttt
    41701 taaattttta tctcaaaaat attttttcgt tcaaaaaaag gagccatcag ttgatttcaa
    41761 gctccttttt atacagaatt aaactatttt atagttcgac aatcttacct gtttcaaagt
    41821 agacaaccca ttcacagata tttttagcat agtcaccgat acgctccaag taggaaataa
    41881 cttggaaata atcacgaccc gtaacaatgg cttctggatt tttcttaatc tcttcagtcg
    41941 caaggtcacg gatagtttca aaatagtggt taatttgctc atccatggag gccacccggt
    42001 atgcgtcgtc aacagaacca ttaagataaa gatcaagtgc tgcttccaca acgcttttaa
    42061 cttcacgtcc cattttttta atttcttcct ctacagctgg gatgcgttct tcccccttca
    42121 tacggatggt tgcctgggca atggctacag cgtgatcccc catacgctcc acatctgata
    42181 cagccttaag gacagtcaag actgtacgca aatcttgaga gactggttgt tggagtgcga
    42241 tcatttcaaa tgatttcttt tccagtttca cttcgtattc atttacttct gcatcatctt
    42301 cgatgacctc ttttgccagg tcacggtcat gcgtgacaaa agcacgtacc gtacgattga
    42361 tttgtgagag cacttcttgt cccatagcgt agaactggtt atgtaatttc tctaaatctt
    42421 cttcaaattg agatcgtaac atctttcatc tccttatcca aattttcctg taatatagtc
    42481 ttccgtttcc ttgtgttggg gatcaaggaa catctgcttg gtatcattaa attcaatcaa
    42541 atctccatct aggaaaaatc ctgtcttatc agagatacgt gaagcttgct gcatggaacg
    42601 ggttaccaga agcatggtgt acttgtcttt tagaccatac aaggtttcct caattttacc
    42661 agctgaaatc ggatccaaag ccgaagttgg ctcatccaag aggatgattt taggactagt
    42721 tgccaagaca cgggccacgc agacacgctg ctgttgacca cctgacaatc caatagctga
    42781 atcatataga cgatccttga cctcatccca gatagaggca ccttgcaagg ctttttctac
    42841 ggcttcatcc agaacctgct tatccttaat tccattgata cgaagcccgt agacaacatt
    42901 ctcatagata gtcataggga aaggattagg ttgttggaaa accattccga tttccttacg
    42961 taattcaacc gtatctgtac gcggactgta gatgttgtga ccattgtaca ccacggatcc
    43021 agttgtggtc acctctggat tgagatctcc catgcggttg agagacttga ggagggttga
    43081 cttccctgat ccagatggac caatcaaggc tgtaatttcc ttaggttgga aagataggga
    43141 aacactattc aaagccttct ttttattata ataaacggac aggtctgata cctgtaaaat
    43201 cgcatctgtc atacggtttc ctttctaacc aaagtgacca gatacatagt cattggtgga
    43261 ctgtagcttg gcattttgga aaatagttgc agtcttgtca tactcaatca aatcacccaa
    43321 gtaaaagaag cctgtatagt cacttgcacg agcagcctgc tgcatattat gcgttacaat
    43381 gatgatggta aagtttttct tgagctcaaa catggtctct tctagttgca tggtcgcaat
    43441 cggatccaag gctgaggctg gctcatccat taagaggata tctggcttaa cagagatggc
    43501 acgagcgata cagagacgtt gttgctgacc acctgataag gtcaaggctg acttgtggag
    43561 atcgtcttta acctgatccc agagggcagc ctgacgaagg gaggtttcta cgatttcatc
    43621 taggacttgc ttatccttaa ctccagcacg ttcatgcgca aaggtaatat tacggtaaat
    43681 tgacttagca aatggattgg ggcgttgaaa aaccattcca atgtgtttac gcatttcata
    43741 aacgttgatt tctggacggt tgacatcaat tccacgatag agaatctgcc cagttacttt
    43801 agcaatatca atggtatcat tcatgcgatt gagactgcgt aagtaggtag atttccccga
    43861 tcccgacgga ccaatcaaag ctgtaatttt atttctttca aattgcatat caatcccctt
    43921 aatggattca tttttaccat agtaaacatg gacatcctta gtagaaaggg ctactttttc
    43981 ttcaggaaag gtaaggatat gcttctcatc ccagttatat gttgacatgg cttctccttt
    44041 aggcagcggt taatttcttg tgtagatagc ttccgaactt acgagctcca aagttaaaaa
    44101 tcaggataaa gatcaggagc acagcggcag aacctgctga tacaatggtt ccatctggaa
    44161 tagtgccttc actattgact ttccagatat ggacagccaa ggtttctgct tgacggaaga
    44221 tagagatggg gctagtcaca ctgaggatat tccagttaga ccagtcaaga gctggcgccg
    44281 attgccctgc tgtatagatc agagctgcag cttcgccaaa gatacgacca gatgccaaga
    44341 cgacacccgt tacaatacct ggaagcgctt ctggaataac aacatgaacc actgtctccc
    44401 agcgagaaat cccaagagcc agaccagcct cacgttgggt atggtgaacg tgtttcaaac
    44461 tatcctctac attacgcgtc atctgaggca agttaaagac tgtcaaggcc aaggcacctg
    44521 aaatgattga aaatccatac tcaaactgaa ctacaaagat caagtaacca aagagaccca
    44581 ccaccactga tggtaaagag gacaagattt caatacaagt ccgcacaaag ttggtaacag
    44641 gacctttttt agcatattca gccaagtaaa tcccagctcc catagaaaga ggtacagaaa
    44701 taatcaaggt aatgaccaat aggaaaaagg aattgtaaag ctgaatgcca atcccaccac
    44761 ctgcttgaaa agcagaagac cttccagtca agaaagacca agagatatgg ggcaagcccc
    44821 gaaccaagat atagagaatc aaggaagcca agattgtcac aatgatgcta gcaatcgtat
    44881 agaggacagc tgttgcaagt ttatctaatt tcttagcgcg cataattttt ctttcctctt
    44941 tctttcgtaa tcaatttaat cacactgtta aaaactaaac tcatcaagag cagtaccaag
    45001 gccagtgacc agagaacatt attatttaca gttcccatga cagtgttccc aattcccata
    45061 gttaatatag aagttaaagt tgcagctggt gtggtcaagg aagttgggat aacagctgag
    45121 tttccgacaa ccatctggat agctaaagcc tcaccaaagg cacgcgccat cccaaagacc
    45181 actgcagtga aaataccaga acgggccgcc ttcaagatca cacgccagat agtctgccag
    45241 cgagtggctc ccatagcgaa actggcttca cgataataac gaggaaccgc acgcaagcta
    45301 tccgttgtca taaaggttac ggtcggcaaa atcatgacaa agaggacgga aatccctgac
    45361 aaaatcccaa aaccagtccc accaaagaca ctgcgaacaa agggaacgac gacttgcaag
    45421 ccaataaatc cgtacactac tgaaggaatc ccaaccagga gttcaatagc tggttgcaaa
    45481 atcttcgccc cttttggtga tacttcggtc ataaaaactg ctgcaccaat agcaaagggg
    45541 gttgcgataa gggctgagag aatggtaacg ataaaggaac ccaaaatcat aggaagggca
    45601 ccaaattctt tactagaagg attccaaatt cctcccaaaa gaaagtcaaa gatattcaca
    45661 ccattgacaa agaaggtcga caagcctttt tgcgctacga aaaccaaaat catggccaca
    45721 aggatgacta tcaaagaaag acaggcaaag gtcaaacctt ttcctaattt ctccagacga
    45781 gaattctttg atggaagcaa cattttctta gctaattctt cttgattcat tattgtctcc
    45841 cttccaacac tgtcacagtt ccggcagcat ctttttcaac cttcatttcc ttaatcggaa
    45901 tatacttcaa tcctttgaca atcccttctt gggtctcatc cgagagaaca aaattgagaa
    45961 attctgcagc caactcattg ggctgcccca atgtatacat atgctcataa gaccacaagg
    46021 gccaattatt gctacttata ttttctggac ttaagtcata gccattcaac ttcatgcttt
    46081 tgaccgaatc atctatatag gtaagagata aataagagat agctcctgga ctttttgata
    46141 cgattgattt taccgctcca tttgaatcct gctcctgact ttgcatggca gactgacctt
    46201 ccataatgac agtatcaaag gtagcacgag aaccagagcc ggctgcccga ttgataacag
    46261 agatgggtaa gtccttacca ccaacctctt tccaattggt tacctcacct atgaagattt
    46321 gacgaagttg ctctgtcgtt aggttatcaa catcaacctc cttattgaca atcagagcca
    46381 agccagctac cgcgaccttg tggtcaacaa gagcagaagc atcaattccg tctttttcct
    46441 cagcaaatac atctgagttt cctatatcaa ctgccccaga ctgaacctgg gacaagcctg
    46501 taccagaacc tcccccttgg acattgaccg tttttccaac atggatcgtg ccaaattcat
    46561 ctgccgctac ttcaaccaag ggttgcaagg cagttgagcc aacagccgtt atggattctc
    46621 cacgatcaat ccagctagca cagcctacta aacaagccgt cagccaaaaa gcgataagag
    46681 acagagcaag cttttttctt tttttcactg tttttctcct cgaaaataat tatgaatact
    46741 gtgaattttt taagtagttc tttatgagtt gacgcatgaa ttcttaccaa atttctgcgc
    46801 aattgattat ttatataata taggctatat tactctttcc taacctcctt ttttcatatg
    46861 tggataaaat ctcttgtcta tcccttcccc cattgtcacc cattatagtc atttcgtgtc
    46921 tctttttccc ctttttaatg caagggaaat tactctcctt agatgataat ccaaaagcta
    46981 gaaaggtatc tcaaacctct ctactctccc agactagttt acaactaaaa ggaaaagatt
    47041 ctattttatg agaaatctag tttacaagcg gtaagaacgc taataactaa acttcttgta
    47101 ctctttgaaa atctcttcaa accagtgttt tgagctatct atggctagct tcctagtttg
    47161 ctctttgatt ttcattgagt agtaaaacta catgtaatgg caatcaagat atcaagaatc
    47221 atcctactaa aaaaatccat actttcacta taacatagaa taagatattt gactagcatt
    47281 ttcatttgaa tctgaggcct tttggaaaat aatttttcaa aacatttcca gtaacctttg
    47341 caaagcccaa gccattgcct ttaaccaaaa cttggtacca accatttggc agactttctg
    47401 ccagctgaac gatttctcca gccgcatact tgacaaacgc ttcttggcca atttcaaccg
    47461 actgttcgac ctgactcgat ttcaaggcta aaccaagagc gaaactgggc tcaaagcgtt
    47521 tcttcttaaa agtacccaga tgcagtccat tgcgagcaat cttgagcttc cctaaatctg
    47581 gcaaaagttc tggcaagaga taaagctggt ctccaaaagt ctgcaagata cccggtagat
    47641 tgaccttcaa atggttttgg gcaaattcct gccacaaggc aacttgttca cggctgaggt
    47701 tactcttact tgccttaaat ttaggagctg gattgttacc cttaaactgt agatgggcaa
    47761 caaactgacc ctctccctta aactgatgag ggtacatccg agccgtttct ggcaggtcaa
    47821 taccagctac cattccattg atatgctcta ctggcaacaa gtcaaaatca tactcttcca
    47881 gcaaccaatt gacaatctct tcgttttcct cgggtgccca ggtacaggtc gaataaacca
    47941 gacgaccacc ttcagctaac atggtcactg catcctccag aatttctctt tgcaagctag
    48001 cacattgact cggataatct aagctccaat agtccatagc atcaggttgc ttacgaaaca
    48061 ttccttcacc agagcaaggg gcatcaagaa cgattaagtc aaaatagcct ttaaagacct
    48121 tgaccaagcg gtcggcagat tcattggtca ccacgacatt tgtcgctcca aaacgctcca
    48181 tgttttcaac caaaatctta gcccgtttgc ttgaaatttc attggaaaca agtagcccct
    48241 cccctgctag ataggctgcc agttgagttg atttgccccc cggtgcagca gccaagtcca
    48301 agaccttcat accaggactg ggttgggcta cttgagccac catttgagca gcaggttctt
    48361 gcgaataaac taaacctgta gcatgctcag gcgatttccc tgaaaccttc ccatagtggc
    48421 cccaaggggt ttgagtaatg gcatcagaaa aggaaagttg ctcttctttt aagggattga
    48481 cccgaaaggc cgaaaccgct tcctcctcaa aagaggcaag aaaatttctt gcctcatctc
    48541 ctagtatttc tttatatttt tcaacaaatc cttctggaaa ttgcatttaa gttcttttcc
    48601 tttcgtaaat ataggactga atttcctcct gcatctcaag aggcaccatc atgacaggct
    48661 gtctggtttg aaaatcagga gcttcaccaa aaagggtcac aacccgatag cccagacttt
    48721 cccctaaaat actagctgcg gcataatccc atggttgcag ataagtgaga taggtcaaca
    48781 aacgccctga caaaatcttg gcaaaactaa tggccgcact tccatagaca cgaacaccaa
    48841 gaaccgctcg gctcaaatca gccagccccc attcattggt ttccagcata ccactattcc
    48901 ctgcaatgag aaaatctcca agtggtttag ttttaaaagg agctaggggc ctatcattta
    48961 gacaaactgg aaattcccca ccaccgtggt aacaatcccc tttgaccaca tcataaatca
    49021 gaccaaactg tccctgacca ttttcaaaat aagccatcat aacagcaaaa tcttcctgct
    49081 gggctacaaa attattggta ccatcaatgg gatcaatgac ccaaaccttg ccctcttgaa
    49141 ccgaggctcg cagacaacct tcttcagcac aaatcttatc ctcaggataa cgggacaaaa
    49201 tctcaccaac caagagttcc tgaacttctt tgtccagtct agtcaccaaa tctgttggag
    49261 aggacttggt ttcaacacgc aagtcttcct gcatatggtc aagaatgtac tgacctgctt
    49321 tcttaacaag ctctttagca aattcaaatt tactttccaa gagaaatctt tccttcccct
    49381 ttttctttgg cagcctgaac tgctcggtaa agtgaatagc cactaaccgt ttcaaattct
    49441 cgtcccaaac gtttctcttc gctcttgctt ggcacgaccg ctttgaatcc cttataggag
    49501 tccagtaact ttttagcctc tactttgcct tcataggcag cttcaacatc attaaaaaaa
    49561 gaaagcactg aagcaagttc ttcagtgctc cacgacaaat ctagtgggta actatactgt
    49621 ttgttcatta actaatacca gctctcattc ttgcttcttt tagttcttgc ttacgataac
    49681 tacgagggag aaaagcacga atctcatctt cattaaaacc gatttgcata cgcttggcat
    49741 caataataat tggacgacgc aaaagactag gatactgctc aatcaaatga agcaattccg
    49801 ataccgaaat actctctaca tcaatattca atttttgaaa aatttttgaa cgagttgaaa
    49861 tgatgtcatc agtaccattt tcggtcaagg aaaggatgtg ttgcaattct tttcttgtta
    49921 aaggactggt cataatattg tgttccacaa agggaacctt atgtttttct aaccaggcct
    49981 tagccttacg acatgatgta cagctcggtg atagaaatag tgtaatcatg cttttctctt
    50041 cttatctata ctttgctact tctattatac aaaaaaataa agcgcttgac tagggatttt
    50101 tagaaaaaaa gcctattttt tcaagaaaaa taggcttttt gcgaacgatt gacacaattg
    50161 gatttggtta attcactctt aacgatggtt ttaaatgata tatattttta tatatgtaaa
    50221 ttaaaaacat ctttcctttc acttcctacg acttttcaga tacagatagc caaagaagtt
    50281 ttcatagagg gcaaaaaaga ggaggaaggc atgaagaaag aaggtctctg gcaaaatcat
    50341 aataacagga tccttggctg gatcaaaaag ccaggtatca tctcccacaa agagaatttg
    50401 atggaaaaga gtaaagaatt ggtcaaaacc aatcaaaact cccccaagtc caatcatcac
    50461 aggtaagact actagagcca ggagactttt tcgataaaga gacaaaaagt cctttttcac
    50521 aatcctattg acaaagacat agaaacttgg cagtgtcact agagctacta gctgaaccaa
    50581 atgaaagaga ttcttgacca ctgcgaaatg gtgcagacca gctgctgacg aacgaaaatc
    50641 aggcatctgt aagacctgac taaaaggatt ggtcagataa ttcatcaaga tatgaaaatt
    50701 gtattgaatg gtttctggtt ttagatagac tcgattcgtt aagtttagcc actgaatctc
    50761 cataggatag aaaatccaag ccagataaat ggtcagaagg attgagaggg agaggagaaa
    50821 gagcatagag ccccaaaagg tcaatttagt tttcatcaaa atcccactcc gcaaggctag
    50881 aaaccacatg tgtcggtgcg attggcaggc cagctacttc ttctgcctta gtaaaacctg
    50941 tcgtcaccaa gagcgttgga atgccattgt caatcccagc ccggatatca gtcaaataat
    51001 tgtccccaac catgattaac tcttcacgtt ccaaacctaa gtgctcaacc gccttgtcca
    51061 taatgatggc atttggtttt ccgatataaa ccggcttcac tcgtgtcgct acttcaagca
    51121 gcgtaatcag tgagccagca cctggcaaaa gaccgcgttc cgtcgggatg ttgaggtcag
    51181 gattggttcc gataaaatgg gcaccctttt gaatagcaag agttgctgtg gcaaattttt
    51241 catagtcgac ttgccaatcc agaccaacta ccacgtaggc agggttttcc ttgtcttcca
    51301 cataaccagc cgccttgatg gcttccttga gtcctgcttc tccgacgaca tagacggtct
    51361 tttcaagccc caaatcattc atatagtcga tggttgccaa agtcgctgtg tagacagtcg
    51421 ataggggcgt atcgatatta aaattctgag ccaacatctc cttaacactc tctggagtgc
    51481 gagttgtatt gttggttaca aagagatagg gaatgccccg cttttgcaat tcatgaacaa
    51541 aagtctctcc agcagggatt cggtctttcc ccttataaat ggttccgtct aaatcaatta
    51601 aatagccttt atatttcatc tatttctccc taagcctttt ttatttcttg ccaagtaatg
    51661 attgcttggg cattgataac cccatcactt gtaatttcat gcttgctttc cagtccagtc
    51721 cgttcaacaa ccgatgtaat cactccacct ggtcgaactt ccttgacata cttgaggttg
    51781 attttcttgg gaatatagtg ggtcaaaaaa tccgctccca tgacctcaaa aatccagtcc
    51841 aagtatttac tgttattgac atgaccattc atatccaagt cgtaaaaacg aacatggtaa
    51901 tccttgctga tcggttcttc caaggactca tacttcggtc cacggataag ttttttatca
    51961 aaatcagact ggtaaggagc cacaatctca ggttcaacag catggacttt tcgactgtcg
    52021 cggtccatga gaacaaaggt cgccatcata tggatgagct cctgccccgc ttcattataa
    52081 atagtaaagc gacggtagca aaaaagtcga ttgtagctca aggcttccgt ttcgatggta
    52141 atttcttccg caaaacgagg caaacgaacc acctcaatat catattctgc gataatccag
    52201 accagattat agtcttccaa aatggcctta tcactaactc ccagttcaat cgactgcatc
    52261 cctgaaactt gcagtgacag caaaatcaca tctggaagtt tgatatgacc gttcatatca
    52321 gccatatcaa aaggaatttt cattttcatt tgataagtta agcccatgat cctactccaa
    52381 aataaatcgt tctgctacag tatctcccaa aaagagacct ctctttgtca tgcgaacgtg
    52441 gtcaccctca atctgcatga ggccttgttg aaccaaatct ctgacaattt ctccataaag
    52501 tccagcaaaa gactgtccaa atttttcctc aaatcgcgcc atggaaaccc cggatttctt
    52561 gcggagtccc aagaacattt cttcttccat ttgctccttt tgactcaggt gatcttctgt
    52621 aatacaagca ttgccttcct caaccgcact gagataatga cgaatgggac catgattttt
    52681 ataacgtact ccattgacat aaccagatgc ccctgcacca ataccatagt attcagcatt
    52741 gtcccagtac atgagattat gacgactttc aaagccgggt ttggagaaat tagaaatctc
    52801 ataatgctca aaacccgctc gctccagctc tgcaatgatg tactcaaaca tctccgcttc
    52861 tagttcctcc ttaggcagag gcaatttccc acgtcgcatc cggttcataa agaccgtatg
    52921 gttttctaaa atcaaactat acaaactcat gtggggaata tccagtccaa tggctttagc
    52981 cacattttcc tttacttgct ccatggtctg accaggcaga gcataaatca aatcaatgga
    53041 gatgttgtca aaaccagcca gtttcagacg atcgatattt tcataaatat ccttctccaa
    53101 atgactgcgc ccaatctttt tcaacatctt atcatcaaag gtctggacac ctagcgaaac
    53161 acgattgaca gccgaatttt tcaaaacagc tatcttatcc gcatccaaat cgcctggatt
    53221 ggcttcaatg gtcaactctt ccaagacaga caagtccaag tttttagtca agccattcag
    53281 taacacctcc agttgcggag ccgacagggc tgtcggtgtt ccaccaccga tataaagggt
    53341 tgacaacttt tcaatatcat aagaacgaaa ctcttccagc agatgctcta aatagctgtc
    53401 gactggctga tttttgatga agacctttga aaaatcacaa taataacaaa tctgggtaca
    53461 aaatgggatg tgcacatagg ctgacgttgg ttttttctgc atagtaatta ttataccaca
    53521 aagactagat tccagataaa aatcaccatc cccagataca tagtccgtcc ggagatggtg
    53581 atggtttatt cttctgttat atcaatcaca atctcttctg agtcatcaag agcttcggct
    53641 ttttcttgcc attgttcctt gagattattt aattgatttt ttgatgcttc tgtcgcttga
    53701 aaagcatagg atttagcttg agcaagtata ctgtccacag tgatttcacc tgactcaacc
    53761 tgttcttttg ttttcagaac aaaatctgta gcctgctcct taacttctgt cagtttttca
    53821 cagacttgct ccttggcata ctccggatct tctctcaaat catctagaaa atcttgagcc
    53881 tgactgcaaa cttgtttgcc cttatcactt gttaaaaaca aggcaagagc tgcacctgaa
    53941 accgttccta aaaggattga ggataattta cccataagga ttctcctttt ttattttttg
    54001 aaaaatttac ttgcaagacg aagagctgac agacttgcac cagtcttgag tgtttttgaa
    54061 ccagctgatg aagctttctt gctcaagaca cgcgcatggt cattgaggtc tgaaacagat
    54121 agagataaat ctgcaacagc actgaagagt ggatcaattg tagccacctt gacattgata
    54181 tcatctgcca agacattgac cttagccaac aactcattgg tgtgatgcaa ggtcacatcc
    54241 acatctgaag tcaaggtttt aatcgtcttt tctgtttcat cgatgacacg accaagcttt
    54301 tgtacagtaa tgatcagata gaccaaaaag acaatcaaag ctagggcaac aagaatatat
    54361 gcaacttcta acatttagtt ttcctcctct gtaatatagt aaggggcctt ctttcgattt
    54421 tgataaataa cgatcattat accgagaccg ataaggacaa ctgacagcca ttgggacact
    54481 cgaaggccga agaacatgag actatctgtt cgcatacctt cgataaccat acgaccgaaa
    54541 ccataccaaa tcaagtaaaa ggccgtgata tgacctcgtc tgagactctt ccatttccgt
    54601 ctaaaaatca gaatcaaggc aaagccaagc agattccata gagactcata aaggaaagtc
    54661 ggttgacggt agctcccctc aatatacatc tggtcacgga taaagccagg tagataatcc
    54721 agattatcca ctgttgcacc ataagcttct tggttaaaga aattacccca acgccccaaa
    54781 ctttgagcaa tcataacgct aggcgccgca atatctagaa aatcccaagt attgatgagt
    54841 ttacggtcag caaagatata gagcacaaga accccagtta tcaaaccacc gtaaatggcc
    54901 aaaccaccat tccaaatggc aaaaatctct cctaaattct gactatagta atcaaatcgg
    54961 aaaataacat agtagagacg agctcctaaa atagccaagg gaaaggctac taagataaaa
    55021 tctaaaatat cgtctggtat gatcttcttt ctaggtgctt ctttcatagt caaataaacc
    55081 gcaagaatca agcctgtcac aatacataag gcataccaac gaatggctag gggtcctagt
    55141 tgaatagcaa ttggatcaag cattttgcac ctcatttcga gcgattagac ttgtcagtcg
    55201 ttcgtcgaac aaacgggtcg catcaaagcc catttccttg gcacgataat tcatggcagc
    55261 tgcctcaatc acaacagaga tattacgacc tgttttaact ggaatacgaa tacgaggaat
    55321 ggctacgcca gaaacttcaa gttcctctgc attgtttcca agacgatcaa aggtcttatg
    55381 cgtatcgtaa ttttccaaat agacagcaag ctgaacctgt gaagaatcct tgacagcact
    55441 cgcaccgtag agactcataa catcgataat accaacccca cgaatttcaa tcaagtgttt
    55501 caaaatttca gctggttcac cccagagagt aatctcatcc ttggcaaaga tatcgacacg
    55561 gtcatcggct accaaacggt gaccacgttt gacaagctca agacctgtct cgctcttacc
    55621 aattccacta tctccctgaa tcaagacgcc catcccataa atatccatca agacaccgtg
    55681 cacactggta cgttctgcca aacgagaatc cagatagcta gataactctc cagataaacg
    55741 actggtagct gcacggctgg ttaaaatagc aatcttacat tctctagcag cctttaacat
    55801 ctcctctgga accaccaaac cacgggcaac aatgactgct ggtgtctcag gtagaaacat
    55861 ttttttcaaa acttcataac ggctgttgga aggcatgctg atcagataag accactcctt
    55921 catccccaaa agttgaatcc gctctggtgt atagtagtca aaatagcctg tcatttcaag
    55981 accaggtcgc gtaatatccg ctgtattgat ttccttttca agcaactctg gttcaccata
    56041 gacaatatct agtctaagct tttcaatcac ttcttttact aaaaccgaca tcatttcctc
    56101 cttcaaatga gttcttctct ctattatatc aaattgtagg aggaagtttc agatttttgc
    56161 aggctttgga gtatttattt aaaagaaaaa ggactagatt tctctagcct ttcattgcaa
    56221 ttagaatttt ttacgtttac gagctacttc tgatttacgt ttacgtttta cagaaggttt
    56281 ttcatagaat tcacgtttgc gtgtttcttg aagagtacca gctttagtaa ccgcacgttt
    56341 gaaacggcga agtgcgtcgt caagagattc attcttacgt actactgttt tagacatttt
    56401 tttcactccc ttcaagttca atatctattt cattctacac gtaaaaggaa taattgtcaa
    56461 gcaaaaatgc ggtttaattt tgattttttc ttccatttat acaagagttg aaagcgttca
    56521 atagaacatt gcttttttat ttttcgagta agctaagcgc ttcagcatct gcgatgatgg
    56581 ttacatcagg gtgattttgg aggctacttg caggtaggtt ctcagtcact gggccagata
    56641 ctgttccggc aatggcttct gctttcgact caccgtaagc aaaaagaata atagacttgg
    56701 catccaaaat gtttttaatc cccattgaaa tagcttgggt tgggacgtct tcaatcttgg
    56761 caaagaagcg tgcattggct tcaatagtag actggtcaag ttctactaga tgcgtttgac
    56821 tgtcaaatgg agtaccaggc tcattaaagc cgatatgccc attgcgaccg attcccaaga
    56881 tttggaggtc aactggatgg tcagccaaaa tttggttgta gcgttcaact tcagcttcag
    56941 cattgtcctt aacaccacga ggcaagaaac tttctttaaa tggtttttgg ttgaacaagt
    57001 tttcttgcat gaagtaacga taagactgtg gattgtcccc atcaaggccc acatactcat
    57061 caaggttgac actggttaga tttgaaaaat caaggttact ctcaacaatt tccttgtaaa
    57121 attcaagtgg gctacttcct gtcgcaagtc ctagagtttg agctccatta gccaattttt
    57181 ccttcaaaat ctcaaaagca acttttccac cttgaacttg gttttcaact ttaataactt
    57241 tcatcttttc atcctccatt tctatctata tttattatat ggtatagacc aatttttgtc
    57301 aagtgaaaac gatttaattt ctaaaaaaag agcgtccaaa cttgaaacgt gttataatgg
    57361 ataggattag aacttagaaa gaatgaacag atatatgaat acagctgatt ttgatttcca
    57421 cttgccagag gaattgattg cccaaacgcc ccttgaaaaa cgtgatgcct ccaaactcct
    57481 catcgtcaac cgtgagacag gagaaatgca agataaacac ttccactcta ttattgatat
    57541 gctggaacct ggtgatgccc ttgtcatgaa cgacacccga gttctccctg cccgcctcta
    57601 tggtcaaaaa gtggagacag gaggtcatgt ggaacttctc ctccttaaga acactagtgg
    57661 agacgagtgg gaagttctgg ctaaacctgc caaacgcctc aaggtcggta ctcgtatcag
    57721 ctttggtgat ggccgcctca gcgctgtcgt tacagaagaa ttgacccacg ggggacgcat
    57781 tgtccgcttt gaataccaag gaattttcct agaagtcttg gaaagtctgg gagaaatgcc
    57841 tctgccacct tatatccacg aaaaattaga tgaccgtgaa cgttatcaaa ccgtctacgc
    57901 caaggaaagc ggctctgctg cagcaccgac tgctggtctt cacttcacca aagaactgct
    57961 ggcagaaatc caagctaagg gtgttcatct agtctatctg actctccatg tcggactcgg
    58021 aacctttaga cctgtttctg tggataatct ggacgaacac gaaatgcatt cagagttcta
    58081 tcaactttct gaggaagctg ctgccaccct tcgctctgtc aaagaaaatg gtggtcgcgt
    58141 catcgctgtc ggaaccactt ctatccgcac cttggaaact attggttcca agtttgatgg
    58201 gcaaatccaa gcagattctg gttggaccaa tatctttatc aaacctgggt atgagtggaa
    58261 ggtcgtggat gccttctcaa ccaacttcca tctgccaaaa tcaactctgg tcatgttggt
    58321 ttctgccttt gcaggccgtg aattagtctt agatgcctac caccatgcga tccaagaaca
    58381 ctaccgcttc ttcagttttg gtgactccat gtttatttat tgagaaagaa tttctctaaa
    58441 tcttctaata ccaataaatc gctaagatat tatttcaaag aacatctaca attgaaactc
    58501 tagctagctg tagaagaggc ctagtacatt gaaattaaaa tgcttccccc tagcttcgaa
    58561 aatattgcca tagattgcgt tgactctcca aattgattca tctatatttt atttcagctt
    58621 cctatatttt cttcgctgtt tgtaaatcaa aatgcaagac acatgagtag caccatattt
    58681 gttactctta tctgtcctct caagagacta ttatgagtta tttcagaatc attcactact
    58741 ttgaccctga ctctccttag tctcaaaatc aaagacttat actcttcaaa aatctcttca
    58801 aaccgcgtca acgtcacctt ggattatata tgtgactgac ttcgtcagtt ctatctacaa
    58861 cctcaaagca gtactttgag caacctgcga ctagttttct agtttgctct ttgattttca
    58921 ttgagtatta aacaaaaagt gaacaaagct gaattctaat gtacagaaga ctaggcttgt
    58981 tcactttttt atagtcgcta taagatgacc ttatctatag ctttttatat ataattatat
    59041 attcagacat actattatca attttgtcgc agggaggaat ctgttaacgc acccattcac
    59101 cattatcatt gactctatag ccatctatac ttgtattgac cgctaactca cccgatgcat
    59161 ttacataata ccatttacca ccaacttgga accattgatt gactttcata gaaccattgc
    59221 tgttgaggta gtaccatgaa ccattaactt gtacccaacc tgttgccatg gagccatcag
    59281 tattataaaa ataccacata ccattttctt gtttccagcc tgttgttgga gcaactgctt
    59341 tagctggttc tactgctaca tctgttcctt ggttagatgt aacagataca ggatatgaag
    59401 gaatagatga ttgctcagga acaacaactt tttcaggttc tctcgtccct ctccttatac
    59461 gtctttttac catctcttta gtaatttgac gagaagtagt ttcttcaatt gttccatcac
    59521 gttcatctac agcatagatt gtagtaagag taattttacc aatttctcct acttcttgac
    59581 ctttatcaag agttgggtca tcgagatatt ctgtttcgat tggaatttct tggacaagaa
    59641 cttggggctt ggttcctttt ttaacaactc ttgtttgaga gtcttctttt tgacttaaag
    59701 tactctcagt tacttgtcca ctctttccat ctacatcata agttatcgtt gtaactgttt
    59761 tcccattctt tcctagagta atctcttgct cctgtcctgc agaaaggtca ttgtctgctt
    59821 catattcagt agtaaatgga acaagaactt cttcaacctt gcttttagct ggaactttga
    59881 taactgtatc cgtggcttct tttctatcaa cagtaacctg ttcggtaaca taaccagtct
    59941 ctggattaac atcgtaggtc cttgtcgtag ttacatagcc atcctctcca tcaattgtaa
    60001 caggattttc actacggtct tttgtttcat ctttttcata acgaattcgc gtacttgaaa
    60061 ttttcttggt tactacctta ggtttagtcg ctacttttac aataatatcc ccattgtcag
    60121 cgtcatcata ctctattccc tcttctttat ctctagtatc atctctgaca tattgaatcc
    60181 catcagcagc atgaacaaaa cttgtattca gattcctcct aaaaataaag ttagcccgat
    60241 taccgcagaa ccaaaaatct ttccgagttt acgtattgca tagcgcttat tagtattaga
    60301 ttttgccatt acatcctact tctagtatag catcttttct atcaaacgtt aaacaatata
    60361 ctttatatat aaaatagact tagaatgata tattgattac tgaactaaca ctttaactat
    60421 atcgtaatca atctcatata taaaggattg cagacatctt atctaaatac atgctaatat
    60481 atttagatac aaacattcca acttgataat tttcactcat ctttcatcat tccttataca
    60541 actatgcagt ataaatagaa tagttttctc atcagaatga gactatttta atattagata
    60601 atttgataga aaaaacatga ataaaattgg ttgaatttaa ttccctaact cgatagagga
    60661 ttctatttta aatttaacaa cagctaggat tacactataa aaagtacatt accacctgtt
    60721 cggctggaga atctagtcga ttagctccct cttagttaca agcttaaagc gattttttaa
    60781 ctaacactaa accagattaa agaaggaact agaacatctg tcttgtacta atcaatatgc
    60841 tattttaaag tttcaaataa acttggaatg ctaattatta tatttacaat aaatagttga
    60901 cttcgataga aacagaaaat agaattcaac attcttccct acttatacca taataaataa
    60961 gatccgcaag atagcctttt ctctctacac cattaacaat ggtttgtaga taggacattc
    61021 cagccttttc catgacacga cctgaagctg ggttgagact ggcataacgt gctctgacct
    61081 tttgaaaacc tgcttgagta aaacaaaagt ccaagatagc tttcaaagtc tctgtcatca
    61141 taccatttcc ccagtaagcc ttgcctaaca catagccaat ttcacagctt aaatcagcct
    61201 cgtctatctt aacaatgctg atatctccta tcacttgctc tgggttttct tttagacaaa
    61261 tggcccattt ataatagttg agattagtat aggaagcaac ccaattgcaa atcgagtttc
    61321 gagtgatttc gacatcagga ttgggatccc aggtaacata ggtcagattc tcagcggatg
    61381 aagcccaatt ttgaaacatg gcttctgcat cactctccac aaatcttctt aaaatcaaac
    61441 gttctgtctg taatatttgc gtaccgatag atttcatgat gctacctcac ttccttattt
    61501 ctatactcgt agtaaaaagg ctcaactcag taacagctag aaaacgagtt tgtcttctaa
    61561 tttcttgacg cagttgctgc ctggtttgaa atgcgctcta gcaagctttt tcaaacctag
    61621 tcatcgttgc aggggtaaga cgatgaaatc gaactcttcg agttactgaa tctgcctcat
    61681 tttcttattt ctaaactcgg ggttcaagat cccccagacc ttctctcact ttcttatttc
    61741 aagatgagag gctgaaaacc tccagtggag gtttttcttg ctttttaatt tcagggcaag
    61801 aagctaaaaa gtcccccgga ccttcttcgc tttctcattt ctaggctcag ggtaaaaacc
    61861 tccaatggag gtttttactc ccaaaagtca tcaaatacag tgatgggtaa gtggcgtttg
    61921 tgttggcctt tgtgccacca gttttcaatg gtcgcttgag cttctgggct gattgttttg
    61981 ccttctaggt agtcgtcaat ctctgcgtag gtgactccaa gtgcgacttc gtcagctagg
    62041 cctggtttat cttcttctag gtctgccgtt gggatttttt cataaagggc tggctctgcg
    62101 ccaagtttct gcaagagctg ttttccttgg cgtttattga ggcggtaaag agggagaata
    62161 tccgcaccgc cgtcaccaaa cttggtaaag aaacctgtga tattttccgc ggcgtggtct
    62221 gttccaatga ccgctccgct atgggaacca gcaagggcat actgagcaat catacggcaa
    62281 cgtgccttga tattcccctt gttgaagtct gaaacaggac tacctgtcgc ttcaactgca
    62341 gctgtcatgg catcagctga ttccttgata ttcacaacca agctgacatc tggctggatg
    62401 aaggctagag ctttttgagc atctgcttca tcagcttgca ctccgtatgg caggcggaca
    62461 gcgataaatt tgtagctgtc gtctcccgtt tcagatcgca gttcttccat agctaattgc
    62521 gccaaacgcc ctgccaaggt tgagtcttgt cccccagaaa tccctagtac aaaggttttt
    62581 aggaagggat gttttttcag atatcttttt aagaaatcaa tagaacgacg gatttcttcc
    62641 tgggcatcaa tcactggttt gacacccagc tcttggataa tcgtttcttg caaactcatt
    62701 cttcttctcc ttcaccaagg gcttccttgc gcatcttatc aatcaagtcc atcttatctt
    62761 gccatacatc acgagccaaa tccactggat agtgctgcgg attgagcaca cgcttatact
    62821 catcccacaa cttgtcaaat tccttacggg cataatcctg aatgtcagtc aaactaggca
    62881 agttgtaaac taatattcct tctttgaaga tatccaccaa gagaggaacg gcatcaaaat
    62941 tacgaaccgt cttcttgatg tatgtatagg tcggatggaa catcttgatt tctgtcatgt
    63001 cgctaatatc cacaccatca taagtgatat agtcgccttc tgacttgcct ttttcacgac
    63061 tggtaatgcg ccacacctgc ttcttacctg gcgtagagac tttttccgca ttattagaca
    63121 gcttaatcgt attgcgcatc tgaccagttt catcttcgat tgcaacaatc ttgtaaactg
    63181 caccaagagc tggctggtca taggctgtaa tcagcttggt acccacgccc cagacatcaa
    63241 tcttggcctt ttgcatcttg aggttgagga tagtattttc gtccaaatca ttagaagcat
    63301 aaatcttagc ctctgtaaat ccagcctcgt ccagttgttg acggactttc ttagaaatgt
    63361 aggcaatatc cccagagtca atccgcacac ccataaagtt aatctgatca cccagctcac
    63421 gcgccacctg aatggcagct ggtacaccga tgcgaagggt gtcataggta tccacaagaa
    63481 agacacaatt tttgtgggtc gcagcgtaag ccttgaaagc ttcatagtca ttgccataaa
    63541 cctgtaccaa ggcatgggca tgggttccca aaacaggaat gtcaaagagc ttacccgcac
    63601 gcacgttgct ggttccattg gcgccaccaa tcaccgctgc gcgtgttccc cagatggccg
    63661 catccatttc ttgagcccga cgtgtcccaa actccatcaa gggttcatct tcgataaccg
    63721 aacgaatacg agctgccttc gtcgccacca aggtctggta gttgacgatg ttcaaaagag
    63781 ccgtttcgac caactgacat tgggctagag gtccttccac ctgcacaatc ggttcattag
    63841 caaaaaccaa atccccttct tgggcagaac gaacggtcaa ctccaacttg aaattgcgaa
    63901 ggtaattcaa gaacgcccca tgataaccaa gcaactccaa ataggctata tcactatctg
    63961 aaaaacgcaa gccttcaaga tagttcacaa ttctttccaa acctgcaaaa accgcatagc
    64021 cgttcttaaa aggctgttgg cggaaataca cctcaaagac cgccttctta ttgtgaatcc
    64081 cttggtcaaa gtaaacctgc atcatgttga tctggtacaa gtccgtgtgc aatgtcaaac
    64141 tatcatctgg atacatactt ttcctacttc cttagctaga aacccatgaa aattttcaag
    64201 aactttcatg tattccaata aattagtact attatatcac attttagctg gattgagaaa
    64261 agagtaacaa gctattctcc actctccaat tcatccatat cttgttcaaa ttttttctga
    64321 gcccattcgc catagctctt aagaccaaga ttgccaataa agatccacgg aaggtaaatg
    64381 atataagtaa tgacccaagc agacaggtat ttaaaattca aaggattgtg ctgataaatt
    64441 tctatgttga attgataatt ctgcaacatc aaaagagccg taatagccaa ggttaggaaa
    64501 aaacaaccca aaatcgtaaa atgaaaacga ctatagtagg tcactcccag ataacgggca
    64561 cgattgaaaa agtaaaatgt ccctatgatg ataacgatta gcagcatatt agaattaaaa
    64621 aggcttggtg ctaatactga aatgatataa gataggagcg acaaagcaat gcagatatag
    64681 aaactttcag agcccgcttt attgaacagt tgttcttctc tttcgtctag taattgataa
    64741 taataaaatc tatttttcat cttcttcctc ccaaaatagt tggtctaggg ttttccctaa
    64801 acatctgcaa atagactggc agagcgagag actgggattg tattttcccg cctctattaa
    64861 accaatagtc tggcgtgtca ccccgacagc ctctgccagt tgaccttgtg ttaaatcacg
    64921 ctctacccga gctaatttta attttaaatt tttagccacc ttcgtcctcc ttatagtttt
    64981 aatactcatc tactcttaaa aaatccaaaa ccaacacaag ctatcagcta tttattataa
    65041 ccccattaat ttgcattcca gtattatctt cagccgaaaa tcagtatttt aggttgtttg
    65101 aaataaactt cctagtttac tcttttattt ttatttagta ttagctttag taagatcttt
    65161 taaacgaatt tttattgctt atatttcttg tttagtttag ttggtttcat atcactatta
    65221 tataatgctt ttggaaatga gcctagtata agtcaaaaac gtgttgaata gtgaaagcag
    65281 gagcatacca agatgactga ttttttactg tattttaggt atgcaaaata atactaaatg
    65341 aaactaaaat gaatacttct tgcttttctt gagagtgaaa aagtacaata aaatgattgt
    65401 agtgattacc acaagatact gactaataga catcgtattt gaagccacaa atacaggtaa
    65461 agaataaaaa ggaagaagtt caattgcttt gataaacaaa tcattactag tattcatcat
    65521 catcgtattt aatatattag ggataaagag tagtaaagct actaaaatac caaataccaa
    65581 gccacttttc aatttgtata aatagaaaat gtaagataat agaaaataaa acaggactaa
    65641 caaaattgta ttgactacaa tagctactat aaaatctaat cctaaatcac ctggaatacc
    65701 caatttactt actatgacta gtaacacaat gccattcaaa gcataaataa tggaaactga
    65761 gatggcatat agaaaattag acaagacgta aatcatccga ttcttctgtt gattataaaa
    65821 caaacttacc gtattgtggg aaaaatctct actaataact cgattagcat gtataacagc
    65881 cattaacata ccgagcatag cataaaagtt tgaaatatgc ttaataccaa gcgatgtctc
    65941 ttgagtcttt agaataaaga atgtaagcaa tatcggcggt ataaacgaga taagcaaact
    66001 gagatatatt acgcctgatg aatataaatt tcttatattt tccttaagaa aattcaattt
    66061 atttaatttc atgattataa ccttccttta ttttgaacga tttaagtaaa tatctttaag
    66121 cgtctctttt ttagtttcaa aatcaactac tttaatagag ttttcgttaa aaaatttaaa
    66181 aagctcacta ctttgaatat tcccagacat agtaattctc agtccctctt cctgaacaat
    66241 atccccaaat tcttgtttgg taatgaaaat gtctctatct gtagctgatg aaaaagctat
    66301 ctcaaacaag aaattatgac tatcttttcc tactttttga aatgtcaaaa gcccgctctc
    66361 caagaaaaga accctctcac aaatttcttc aatgtcttct aatttatgac tcgatattaa
    66421 aattcccacg ttttcattta aagctaattt ttttagaacc gctaaaacta tttgtgatga
    66481 ttcaatatct aaaccattag tcggttcatc taaaatcaat atatcaggtt tcgtaacgag
    66541 agttagaagc aaagctaatt tttgttttgt acccaaagaa taggtcttta cttttttatt
    66601 aatagactga gtcaaatcta actcttggat caaacttcta aatctttctt gattgtagtc
    66661 aacaccatat aaatttgaca aatattttaa attctctaaa cctgttttag ataaaaataa
    66721 ttttggttct tcgattaaat acccaatatt atcactgctt ataatattac ctgaagtcgg
    66781 ttgattattc tgaacaagaa ttttcatcaa cgtactctta ccaactccat ttctccctac
    66841 tagaccaaca atttcaccct tgttaagtgc aaaatttata tctttgagaa tgattgaatg
    66901 accataatgc ttacttacat ttataactta cattttttat tcctccatta atattcatgg
    66961 tttgctcttt gattcttatt gagtttaaaa agttgcgcct ctttttaaca acattatatc
    67021 atatatctaa cttaatgcaa tatataaatg tcattttgta aaattttatt aacaaaaaac
    67081 tctctacaac aaaataatag agagttttct gcttattaat ttttttcaaa atatctaaac
    67141 atcacttctt tgtttaattt gataggcttt gatacctaag ctccgacttt atcacttaaa
    67201 aaataaaaaa ggacagctaa tctcttgcgc atcaagggat ttcgccattc tttaatctcg
    67261 tttaagtgtt gtatatggag ctttgcataa ttttttaaaa ctaaacaact acattaaac
//
LOCUS       DAVLMQ010000007        51653 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000007 DAVLMQ010000000
VERSION     DAVLMQ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 51653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 51653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..51653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.007"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(175..252)
                     /locus_tag="VXF95_000555"
                     /pseudo
     CDS             complement(175..252)
                     /locus_tag="VXF95_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            323..979
                     /locus_tag="VXF95_000556"
     CDS             323..979
                     /locus_tag="VXF95_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HEV1081143.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTDLGGLLPNPEIFGLDFALVGMFIGI
                     FASQFQMMQRRIPVRNLLIILAVVAVSFFLLLTVVSQSLAVLFATLLGCSMGVVLDGQ
                     "
     gene            969..1292
                     /locus_tag="VXF95_000557"
     CDS             969..1292
                     /locus_tag="VXF95_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000253911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HEV1081144.1"
                     /translation="MVSKYLLLAVIFSGLVTWILRMIPFILVKYKGLPAIVERFLKFL
                     PVSIIFALILSSVVTGKVGSLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAI
                     LRLVF"
     gene            1395..2225
                     /locus_tag="VXF95_000558"
     CDS             1395..2225
                     /locus_tag="VXF95_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1081145.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            2379..3233
                     /locus_tag="VXF95_000559"
     CDS             2379..3233
                     /locus_tag="VXF95_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1081146.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIADTYISPIRLYSGLNGSTNKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            3333..4706
                     /locus_tag="VXF95_000560"
     CDS             3333..4706
                     /locus_tag="VXF95_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HEV1081147.1"
                     /translation="MVFPSEQEQIEKFEKDHVVQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLRGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEDRMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4699..5760
                     /locus_tag="VXF95_000561"
     CDS             4699..5760
                     /locus_tag="VXF95_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HEV1081148.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSDPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5762..6454
                     /locus_tag="VXF95_000562"
     CDS             5762..6454
                     /locus_tag="VXF95_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081149.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6483..7052)
                     /locus_tag="VXF95_000563"
     CDS             complement(6483..7052)
                     /locus_tag="VXF95_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HEV1081150.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPHFGAITTIGLVIALFFLGTKHGAGSFLPGIICGLLADGVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            7187..7801
                     /locus_tag="VXF95_000564"
     CDS             7187..7801
                     /locus_tag="VXF95_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HEV1081151.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7803..9449
                     /locus_tag="VXF95_000565"
     CDS             7803..9449
                     /locus_tag="VXF95_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1081152.1"
                     /translation="MKHFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGHTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVDSIQAIAQGQEGLRIDTLEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRYFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9461..10747
                     /locus_tag="VXF95_000566"
     CDS             9461..10747
                     /locus_tag="VXF95_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081153.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFAIPYYVLGQDWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRVSITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFDQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10799..11332
                     /locus_tag="VXF95_000567"
     CDS             10799..11332
                     /locus_tag="VXF95_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081154.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRAAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELT"
     gene            11410..11880
                     /gene="nrdI"
                     /locus_tag="VXF95_000568"
     CDS             11410..11880
                     /gene="nrdI"
                     /locus_tag="VXF95_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HEV1081155.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHPYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(12173..13435)
                     /locus_tag="VXF95_000569"
     CDS             complement(12173..13435)
                     /locus_tag="VXF95_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HEV1081156.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
     gene            13819..14772
                     /locus_tag="VXF95_000570"
     CDS             13819..14772
                     /locus_tag="VXF95_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element ISSpn8 family transposase"
                     /protein_id="HEV1081157.1"
                     /translation="MQEHYTPKGKHLTIDNRRLIERWKNKNKSNREIAGLLGKAPQTI
                     HTEVKRGTTLQQVRKGLYKKVYSADYAQTVYQFNRKRSVKKLILTKEIREKILHYHKQ
                     KFSPEMMVNKKQVKVGISTIYYWFHNGHLGLTKADMLYPRKRKGVKKQASPNFKPAGK
                     SIEERPDVINLRLENGHYEIDTVLLTKIKNYCLLVLTDRRSRHQIIRLIPNKTAESVN
                     QALTLLLGEHRILSITADNGSEFKRLSEVFPEEHIYYAHAYSSWERGSNENHNRLIRR
                     WLPKGTKKTTPKEVAFIENWINNYPKKCLDYKSPSEFLLGG"
     gene            complement(14990..15448)
                     /locus_tag="VXF95_000571"
     CDS             complement(14990..15448)
                     /locus_tag="VXF95_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HEV1081158.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(15445..15885)
                     /locus_tag="VXF95_000572"
     CDS             complement(15445..15885)
                     /locus_tag="VXF95_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081159.1"
                     /translation="MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPSNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            16241..18190
                     /gene="mutL"
                     /locus_tag="VXF95_000573"
     CDS             16241..18190
                     /gene="mutL"
                     /locus_tag="VXF95_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HEV1081160.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVEQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(18515..18982)
                     /locus_tag="VXF95_000574"
     CDS             complement(18515..18982)
                     /locus_tag="VXF95_000574"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HEV1081161.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(18983..20188)
                     /locus_tag="VXF95_000575"
     CDS             complement(18983..20188)
                     /locus_tag="VXF95_000575"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HEV1081162.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERSGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(20208..20843)
                     /gene="ribE"
                     /locus_tag="VXF95_000576"
     CDS             complement(20208..20843)
                     /gene="ribE"
                     /locus_tag="VXF95_000576"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HEV1081163.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLKQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(20828..21928)
                     /gene="ribD"
                     /locus_tag="VXF95_000577"
     CDS             complement(20828..21928)
                     /gene="ribD"
                     /locus_tag="VXF95_000577"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HEV1081164.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAVIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRESPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHYVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(22062..22176)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            22333..22926
                     /gene="ruvA"
                     /locus_tag="VXF95_000578"
     CDS             22333..22926
                     /gene="ruvA"
                     /locus_tag="VXF95_000578"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HEV1081165.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQEA
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            22936..23499
                     /locus_tag="VXF95_000579"
     CDS             22936..23499
                     /locus_tag="VXF95_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HEV1081166.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQSPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKCLK"
     gene            23496..24173
                     /locus_tag="VXF95_000580"
     CDS             23496..24173
                     /locus_tag="VXF95_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1081167.1"
                     /translation="MMSNKNKGILIFVILYTVLFVFDGVKLLASLMPSAIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLSGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(24310..25341)
                     /locus_tag="VXF95_000581"
     CDS             complement(24310..25341)
                     /locus_tag="VXF95_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HEV1081168.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLPHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDAYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIETGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(25596..26279)
                     /locus_tag="VXF95_000582"
     CDS             complement(25596..26279)
                     /locus_tag="VXF95_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HEV1081169.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGPDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGVALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(26291..27235)
                     /locus_tag="VXF95_000583"
     CDS             complement(26291..27235)
                     /locus_tag="VXF95_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HEV1081170.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            complement(27396..28562)
                     /locus_tag="VXF95_000584"
     CDS             complement(27396..28562)
                     /locus_tag="VXF95_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1081171.1"
                     /translation="MKITEVIKKDGSKVYRANVYLGVDQVTGKKVKTKVTGRTQKEVK
                     QKANQEKIAFQKAGSTRQKAVTIKNYQELATLWLESYKNTVKPNTQGNVKKLIDNHIL
                     PIFGAYKLDKLTTPLIQSIINELADKTNRGEKAAFLHYDKIHALNKRILQYGVTMQAI
                     PSNPARDVVLPRNTQKAKRKKVKHFENQELKKFLGYLDNLDTHRYRYYYETTLYKFLL
                     ATGCRINEALALSWSDIDLDNAVVHITKTLNRDIEINSPKSKASYRDIDIDQATVSML
                     KQYKLRQTKEAWKIGQRERVVFSDFIHEYPSSSRLKRRLQTHFKRADVPNIGFHGFRH
                     THASLLLNSGIPYKELQYRLGHSTLSMTMDIYSHLSKENAKKAVSFYETALKAL"
     gene            complement(28647..30161)
                     /locus_tag="VXF95_000585"
     CDS             complement(28647..30161)
                     /locus_tag="VXF95_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA binding domain-containing protein"
                     /protein_id="HEV1081172.1"
                     /translation="MRKYDIPKLLLSGENQGVEFKEAKNSFPKDGMKTICSFANTNNG
                     LLILGVSENTKNKDFYISGVNDPDKVLDELYSLLNNPNKINRNVINEESVEVVNIKGK
                     EIVIIPVNKVDYKDKPIYLNDNIASTYFRQGTGDFRCSQEQINSMLRDSAKESFDSTL
                     IQDFSILDLDTETIKLYREKFDNINAEHPFSKLDNEQFLIKINALRRDRKDDKIKPTV
                     AGLLIFGTHNSIKEFIPHYNVEYVLKEFSENNRFKDRVIYDGTWGEDNLFNFFYLVIE
                     KLYLTLNDNSNIQENSMNRIGISKLRIAIREAFINSLIHSDYKSEKGIMIIRYPDRYI
                     FTNGGTLRIDIKDFFSGAHSDPRNYLIQEIFRFLNLCEKAGTGIPKIMEAVKESHLKY
                     PNLRTELDSVEFTLWDTSLIDNLDIDNEYEKKILELIIEHRFVTREALEEKLKIHKNT
                     ILKYLKKLVEKQAIDKFKSGRQYVYFITQNQDPEFQKYNHINAMYSLLEEIKRK"
     gene            complement(30322..31035)
                     /locus_tag="VXF95_000586"
     CDS             complement(30322..31035)
                     /locus_tag="VXF95_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001107589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1081173.1"
                     /translation="MAKNSPQDLKNREYFSNNLNRVMKEKGIRQIDLHNALEIPKSTI
                     TGYVKGRSMPTSGNLQKLADYLGVKKSDLDPRFSDKDVYKEFLYMLDKQLDEEKYLVK
                     NVSKDKIFQKVKEREKRDKEIIELAKSKNFPISPEEFLTTITESLNEYNPKDNYEVLN
                     ALALKTSNILFWLDIVFQKTSSEFYIVFEDKEFNQEYYNKLYKKFENLFEEIKSLALQ
                     EAKKDKENLDDFALLWGID"
     gene            31146..31772
                     /locus_tag="VXF95_000587"
     CDS             31146..31772
                     /locus_tag="VXF95_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HEV1081174.1"
                     /translation="MELVYMDGKKEPYTLSSIVAECAEVKHRHLKILLNKHREDFESF
                     GKVQFKISPSESGQNVRDYILNEQQATLLITYLRNTEPVKEFKKNLVKAFFEMREELS
                     KFRMQRALEKPKRKTLHDSIETWEAKPKHAHSTMNNLLLKAVTDMNAKQLREERGGYN
                     GIDSLTSDELEQYQAFEDMVIAMIGLNMSYQEIKAMAFRNKKTRQRSA"
     gene            32144..32596
                     /locus_tag="VXF95_000588"
     CDS             32144..32596
                     /locus_tag="VXF95_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081175.1"
                     /translation="MTETTYENLTRHIDRISAEMREIGEKNGLSRLSLLANQTKFIKE
                     NLHRLLWIELPELNDSHKIEAVSKSTTGMFFHAGIFEMDAMRQAFFKRQAMHFFDNEA
                     EQQAYIEHAEKEYLEATITLKDILFNSKNGTQRVNKSCLIEKFEEAMQ"
     gene            32593..32793
                     /locus_tag="VXF95_000589"
     CDS             32593..32793
                     /locus_tag="VXF95_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081176.1"
                     /translation="MTLNLDNMTQAEFDEVMAEIKEKRPNLFQFIADFVDRKVSTEEV
                     DEYLKMKHEKQVEFIKNYQARA"
     gene            32795..33010
                     /locus_tag="VXF95_000590"
     CDS             32795..33010
                     /locus_tag="VXF95_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081177.1"
                     /translation="MNELDLTNTQSVIFMVVLIGLLLYLNHRDRKKSAQFERENQQRI
                     ETPSEDLSPDYGRYIQLAGVRVYGGTE"
     gene            33007..33348
                     /locus_tag="VXF95_000591"
     CDS             33007..33348
                     /locus_tag="VXF95_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1081178.1"
                     /translation="MSLSENDKRVLRLIKVGAENSITGAEISLITKLAERTVQDIISR
                     LITRHSVPIVGVRHGTFRGYFIPANKEELLDGAKAFYNQVQEEQKRLTVLLNADLESY
                     KETLKEVGGYV"
     gene            33341..33622
                     /locus_tag="VXF95_000592"
     CDS             33341..33622
                     /locus_tag="VXF95_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HEV1081179.1"
                     /translation="MFSLSRESEQDLAHGILEVVERYLEARDTVKPRLTGLISAQEVM
                     DELDIKYMTLQKWEKAGLRRYQPPLEDTRKIYYKISDIWKFLGVENGKV"
     gene            33757..34623
                     /locus_tag="VXF95_000593"
     CDS             33757..34623
                     /locus_tag="VXF95_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primase alpha helix C-terminal domain-containing
                     protein"
                     /protein_id="HEV1081180.1"
                     /translation="MTIYEAKGFQSNLVYPFDKIEPFQYIERFKPLVVPEGADIEEYK
                     RTQAPYCISGKVTPEKHGSYKRNNSSLIYRDLIFLDYDDIQGTSEGFIKAISSALFGY
                     SYILYPTIKHSLEKPRFRLVVKPDNVMNEATYKQVVKEIADKIGLPFDMASLTWSQLQ
                     GLPVTTGDPASYQKIVEHGLDYPVPQTTAEPVKQNAASLPYTPRPSGQKSMTMRIIDT
                     LFNGFGDEGGRNVALTRFVGLLFNKWVDCDLETAYELTKIANSVTVEPLPIEELDRTF
                     SSIARAEYRKRG"
     gene            34676..36145
                     /locus_tag="VXF95_000594"
     CDS             34676..36145
                     /locus_tag="VXF95_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase family protein"
                     /protein_id="HEV1081181.1"
                     /translation="MEQEHPPRTMKELENRIFKAGEEWRAEHTETKVNENTGDVTEKV
                     AMPQTFTVAKILSEIVTFTFISKSNIPDYSLLYIYDLDEGIYTASNDLFNLLCKTFDV
                     RIKPREWPQIKLMVRTLAKIRKPLESANLIPVQNGIINLETKELLPFSPKYVITSKIS
                     TAYHAPKRVPTDREGKTFDDWLNSIACNDSELVTLFWQIILEAINPNHTRNKFAIFYG
                     DGNNGKGTFQRFLINLIGESNISALKPAQFAEKHNLETLVGKVCNIGDEAPNEYLKNP
                     SDLMSITSGDTVLVNPKGRPAFEATFKLFNIFSGNYIPNGGNKTKGWYRRIMIVPFNA
                     DFNGEKEKPWIKNEFLANKEVLEYALYKAINQEPFTHFIEPKAVKGLLEEYQEDNDYL
                     LSWVKHEYMEKGWHELDVVPVFIVTRSLKHYAEDMGIPKPNVYGAGKETIKHLQQLTP
                     NRYSLRKKRVSPEDFEKLEAWDVDKIKMRTPQHSITKQE"
     gene            36508..36675
                     /locus_tag="VXF95_000595"
     CDS             36508..36675
                     /locus_tag="VXF95_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081182.1"
                     /translation="MKVKLFEYTRRWEKEDFEKEIDDFMATVEVLDVKFSGTPSSESF
                     NSVATVLVLYR"
     gene            36759..37289
                     /locus_tag="VXF95_000596"
     CDS             36759..37289
                     /locus_tag="VXF95_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081183.1"
                     /translation="MTLKTFSSKAKTFTFTYEFKDLDTALVAGHALLGYMTGTYCQPV
                     ISLTYKDKGTLVAEYVEDHKLNKTFKRICDSFKDYHKQPGEAEAFEERYKRERVLQLK
                     ESEDFESLLNKVTDYELELLDYADRLLSDKPIPMDSMTAFATLEMLGDESISLLQKLD
                     VEGEYKGLAGYTEHLK"
     gene            37360..37869
                     /locus_tag="VXF95_000597"
     CDS             37360..37869
                     /locus_tag="VXF95_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081184.1"
                     /translation="MKQLAIEAITKPMKLRGISKGIAELDGQRLEIDLDSLMIDFGGE
                     SFELDRIAGTKGGNRYFFLCPDCGRRCRLLYKRYLYFSCGTCLDIHKHTLNRSKTDCQ
                     YYWELALKEARKVEPGWSPRRGGYMFDSFPERPKYMKQKRYYKHYQKFINYTRKGDSF
                     WLNGLSSLR"
     gene            39076..39495
                     /locus_tag="VXF95_000598"
     CDS             39076..39495
                     /locus_tag="VXF95_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HEV1081185.1"
                     /translation="MTPEQVKEKLEGVKWINKEIKGLYLELETLEGGIIKKPTLSHSR
                     VQTSRENKTENNLISVLKLKEDTLQRIERLTEERMKISELIDKLANPLERSVLRLFYL
                     NDLVVSEVAEEIDRSNTTVYIIRQKAIEHLTGIVNGD"
     gene            39984..42815
                     /gene="uvrA"
                     /locus_tag="VXF95_000599"
     CDS             39984..42815
                     /gene="uvrA"
                     /locus_tag="VXF95_000599"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HEV1081186.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVIGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDDGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            42808..43869
                     /locus_tag="VXF95_000600"
     CDS             42808..43869
                     /locus_tag="VXF95_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1081187.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMGLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            44001..44399
                     /gene="spx"
                     /locus_tag="VXF95_000601"
     CDS             44001..44399
                     /gene="spx"
                     /locus_tag="VXF95_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HEV1081188.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            44465..45034
                     /locus_tag="VXF95_000602"
     CDS             44465..45034
                     /locus_tag="VXF95_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1081189.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLTIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            45121..45387
                     /locus_tag="VXF95_000603"
     CDS             45121..45387
                     /locus_tag="VXF95_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HEV1081190.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            45391..45810
                     /gene="ruvX"
                     /locus_tag="VXF95_000604"
     CDS             45391..45810
                     /gene="ruvX"
                     /locus_tag="VXF95_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HEV1081191.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            45826..46131
                     /locus_tag="VXF95_000605"
     CDS             45826..46131
                     /locus_tag="VXF95_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HEV1081192.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            46390..47640
                     /locus_tag="VXF95_000606"
     CDS             46390..47640
                     /locus_tag="VXF95_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1081193.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLICQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KTLEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            47637..48179
                     /locus_tag="VXF95_000607"
     CDS             47637..48179
                     /locus_tag="VXF95_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HEV1081194.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            48325..49857
                     /gene="cls"
                     /locus_tag="VXF95_000608"
     CDS             48325..49857
                     /gene="cls"
                     /locus_tag="VXF95_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HEV1081195.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            49935..50078
                     /locus_tag="VXF95_000609"
     CDS             49935..50078
                     /locus_tag="VXF95_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081196.1"
                     /translation="MLTKEEVNDMIEFKQTHLHRFREIETFVKLCKKSLKQPSQADNP
                     RTF"
     gene            50115..51653
                     /locus_tag="VXF95_000610"
     CDS             50115..51653
                     /locus_tag="VXF95_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1081197.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVSLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
BASE COUNT        15610 a         9649 c        11134 g        15260 t
ORIGIN      
        1 attcttttca gcctacttat actcttcgaa actctcttca aaccacgtca gcttcacctt
       61 gccgtaggta tggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga
      121 gctgacttcg tcagttctat ccacaatctc aaaacggtgt tttgagctga cttcgtcagt
      181 tctatccaca acctcaaaac ggtgttttga gcaacctgcg gctagtttcc tagtttgctc
      241 tttgattttc attgagtatt attaagacaa tatgaggaga aagatgaaag aaaaaggatt
      301 ttaggagggg gcgcaggcag ccatgccaac ggctcttggc tatgtcagta tcggcctggc
      361 ctgtgggact atcggtgcgc cctatgtgac acctgttgag atgggcttga tgagtctctt
      421 tgtttatgct gggagtgccc agtttgccat gttggcactg attgtggttc aagctcctgt
      481 ggcagctatt gctatgacgg tttttctaat caacttgcgt ctctttttgt tgagtttaca
      541 cgcatcgact tatttccgtc ataccagtct ttggtacaat atcggtatgt ctagtatctt
      601 gacagatgag acctatggcg ttttgatggg tgaattggcc catacagaca aggtaaatcc
      661 tatgtggatg cacggaaaca atcttaacag ctatgtggct tggtttgtgg ggacagtagt
      721 cggaacggat ctgggtggcc tgctaccaaa tccagaaatc tttggcttgg attttgccct
      781 ggttgggatg tttattggta tttttgcttc gcaatttcag atgatgcaaa gacggattcc
      841 tgtccgcaat ctgctcatta tcctagcagt tgttgcggtg tccttctttt tgctcttgac
      901 agtggtgtct cagtcactag ctgttctgtt tgcgacgcta cttggttgta gcatgggggt
      961 ggttttagat ggtcagtaag tatcttttat tagcagttat tttctctggc ttggtgactt
     1021 ggattctccg tatgattccc ttcatcttag tcaagtataa gggcttgcct gcaatcgttg
     1081 agcgtttttt gaagttcttg cccgtttcca ttatctttgc cttgattctt tcaagcgtag
     1141 tgacaggtaa ggttgggagc cttcctcaaa ttaaatggct agacttctta gccgtctttc
     1201 caacagcttg ggtagccttt cgctaccgca atctagtcgg aacagttctc tttggagtgg
     1261 tcttgattgc catcttgcgt ttggtctttt aaattaccca taaaaaaact tatcacagag
     1321 atagatatca tataatggcg taaatgctct ttttctgtta agattataag gtattctatt
     1381 ttggaggaaa tgacatgaaa aaaatcgtta aatactcatc tcttgctgcc ctaggacttg
     1441 ttgctgcagg tgtgcttgcg gcttgctcag ggggtgctaa gaaagaagga gaagcagcta
     1501 gcaagaaaga aatcatcgtt gcaaccaatg gatcaccaag gccatttatc tatgaagaaa
     1561 atggcgaatt gactggttac gagattgaag tcgttcgcgc tatctttaaa gattctgaca
     1621 aatatgatgt caagtttgaa aagacagaat ggtcaggtgt ctttgctggt cttgacgctg
     1681 accgttacaa tatggctgtc aacaatctta gctacactaa agaacgtgcg gagaaatacc
     1741 tctatgccgc accaattgcc caaaatccta atgtccttgt cgtgaagaaa gatgactcta
     1801 gtatcaagtc tctcgatgat atcggtggaa aatcgacgga agtcgttcaa gccactacat
     1861 cagctaagca gttagaagca tacaatgctg aacacacgga caacccaact atccttaact
     1921 atactaaggc agacttccaa caaatcatgg tacgtttgag cgatggacaa tttgactaca
     1981 agatttttga taaaatcggt gttgaaacag tgatcaagaa ccaaggtttg gacaacttga
     2041 aagttatcga acttccaagc gaccaacaac cgtacgttta cccacttctt gctcaaggtc
     2101 aagatgagtt gaaatcattt gtagacaaac gcatcaaaga actttataaa gatggaactc
     2161 ttgaaaaatt gtctaaacaa ttcttcggag acacttatct accggcagaa gctgatatta
     2221 aataatttct tgaaatcatc cattctgagt aaggtgggtg gtttctcagt ttttagggat
     2281 atagttttaa actatatatc tgattatcta ataacaattt gtgaaatcaa acaaattgtg
     2341 agatactagt acggtattat ttttaaggag aaagaatcat gaaaatcaaa aaatggcttg
     2401 gcctagcagc ccttgctaca gtcgcaggtt tggctcttgc agcttgcgga aactcagaaa
     2461 agaaagcaga caatgcaaca actatcaaaa tcgcaactgt taaccgtagc ggttctgaag
     2521 aaaaacgttg ggacaaaatc caagaattgg ttaaaaaaga cggaattacc ttggaattta
     2581 cagagttcac agactactca caaccaaaca aggcaactgc tgatggcgaa gtagatttga
     2641 acgctttcca acactataac ttcttgaaca actggaacaa agaaaacgga aaagaccttg
     2701 tagcgattgc agatacttac atctctccaa tccgccttta ctcaggtttg aatggaagta
     2761 ccaacaagta cactaaagta gaagacatcc cagcaaacgg agaaatcgct gtaccgaatg
     2821 acgctacaaa cgaaagccgt gcgctttact tgcttcaatc agctggcttg attaaattgg
     2881 atgtttctgg aactgctctt gcaacagttg ccaacatcaa agaaaatcca aagaacttga
     2941 aaatcactga attggacgct agccaaacag ctcgttcatt gtcatcagtt gacgctgccg
     3001 ttgtaaacaa taccttcgtt acagaagcaa aattggacta caagaaagca cttttcaaag
     3061 aacaagctga tgaaaactca aaacaatggt acaacatcat tgttgcaaaa aaagattggg
     3121 aaacatcacc taaggctgat gctatcaaga aagtaatcgc agcttaccac acagatgacg
     3181 tgaaaaaagt tatcgaagaa tcatcagatg gtttggatca accagtttgg taataagaaa
     3241 cagggaggtg ggagagaaaa ttccacctct tgcttttgta tagagtatag attgtaaaga
     3301 agactattcg ttcatagaaa ggtagagaga atatggtttt tcctagcgaa caagaacaga
     3361 ttgaaaaatt tgaaaaggat catgtagtcc aacattattt tgaggttttg cgtaccttga
     3421 tttctaagaa atcagtcttt gcccagcagg ttggactcaa ggaagtcgca aattatctgg
     3481 gtgagatttt caagcgtgtt ggagctgaag tggagattga tgagagctat acagcgccct
     3541 ttgtcatggc acatttcaag agttcgcgtc cagatgccaa gaccttgatt ttctataacc
     3601 actatgacac tgtgccagcg gatggggatc aggtctggac agaggatcct tttacgcttt
     3661 cggtccgcaa tggcttcatg tatgggcgtg gggttgatga cgacaagggt catatcacag
     3721 ctcgcttgag tgctttgaga aaatatatgc agcaccatga tgatttacct gtcaatatca
     3781 gctttatcat ggagggagcg gaggaatcgg cttcaacaga cctagataag tatttggaaa
     3841 agcatgcaga caaactccgt ggggcggatt tgttggtctg ggaacaaggg accaaaaatg
     3901 ccttggaaca gctggaaatt tctggtggca ataaggggat tgtgaccttt gatgccaagg
     3961 taaaaagcgc tgatgtggat atccactcga gttatggtgg tgttgtggaa tcagctcctt
     4021 ggtatctcct ccaagcctta cagtctcttc gtgctgcgga tggccgtatc ttggttgaag
     4081 gcttgtacga agaagtacaa gagcctaatg aacgagaaat ggccttgcta gaaacttatg
     4141 gtcaacgaaa cccagaggaa gttagtcgga tttatggatt ggagttgcct ctcttacagg
     4201 aggatcggat ggcctttcta aaacgtttct ttttcgagcc agcgcttaat atcgaaggaa
     4261 tccagtctgg ttatcaaggt cagggtgtta agactatttt acctgcagaa gccagtgcca
     4321 agctagaggt tcgtctggtt ccgggcctag aaccgcatga tgttctggaa aaaattcgga
     4381 aacagctaga caaaaatggc tttgataagg tagaattata ctataccttg ggagagatga
     4441 gctatcgaag cgatatgagc gcaccagcca ttctcaatgt gatcgagttg gccaagaaat
     4501 tctatccaca gggcgtttca gtcttgccga cgacagcggg gacaggacct atgcatacgg
     4561 tctttgatgc cctagaggta ccaatggttg cattcggtct aggaaatgcc aatagccgag
     4621 accacggtgg agatgaaaat gtgcgaatcg ctgattatta cacccatatc gaattagtag
     4681 aggagctgat tagaagctat gagtagagat attatcaagt tagatcagat cgatgtgact
     4741 tttcaccaaa agaagagaac catcacagcg gttaaggatg tgaccattca catccaagaa
     4801 ggggatatct acggaatcgt tggatattct ggagcaggga aatcaaccct tgtacgggtg
     4861 attaacctct tgcaaaaacc atctgcaggg aaaattacca ttgacgatga tgtgattttt
     4921 gatggtaagg tcaccttgac ggcagagcag ttgcgtcgta aacgtcaaga tatcgggatg
     4981 attttccagc attttaacct gatgagtcaa aagacagcag aggagaatgt agcctttgcc
     5041 cttaaacact ctggactcag caaggaagaa aagaaggcta aagtagctaa gttgttggac
     5101 ttggttggtt tggcagatcg tgctgaaaac tacccttcac aactatctgg agggcaaaaa
     5161 cagcgtgtgg caattgcgcg tgccttggcc aatgatccaa aaatcttgat ttcagacgag
     5221 tcaacttctg cccttgatcc gaagacaacc aagcagattt tggccttgtt gcaagatttg
     5281 aaccaaaaat taggcttgac tgttgtcttg attacgcatg aaatgcagat tgtcaaagac
     5341 attgccaacc gtgtggcggt tatgcaggat gggcatttga ttgaagaggg tagtgtgctt
     5401 gaaatcttct cagaccctaa acaacctttg actcaagact ttatctcaac agctacaggt
     5461 attgacgaag ccatggtcaa aatcgagaag caagaaatcg tggaacactt gtctgaaaac
     5521 agtctcttgg tgcaactcaa gtacgctgga gcttcaacag acgagccact tttgaatgaa
     5581 ttgtacaagc attaccaagt aatggctaat attctctatg ggaatatcga aattctcgat
     5641 ggtactcctg ttggagaatt ggtggtggtc ttgtcaggtg aaaaagcagc gttggcaggt
     5701 gcccaagaag ccattcgtca agcaggtgta caactaaaag tattgaaggg agtacagtaa
     5761 gatggaatca ttgattcaaa cctatttacc aaatgtctat aaaatgggtt gggctggtca
     5821 ggcaggctgg ggaacggcta tctacttaac tctttatatg acagttcttt cctttatcat
     5881 cggaggcttc ttggggctag tggcaggtct tttccttgtc ttgacagcgc caggtggtgt
     5941 cttggagaat aaagtcgtat tctggatttt agacaaaatt acctcaattt ttcgtgcggt
     6001 tccctttatc atcctcttgg caatcttgtc accactttct cacttgattg ttaaaacaag
     6061 tatcgggcca aatgcagccc ttgtcccact ttcttttgca gtctttgcct tctttgcccg
     6121 tcaggtgcag gttgtcttgg ctgaattgga tggcggtgtc attgaggcgg ctcaagcgag
     6181 cggagcgact ttctgggaca tcgtgggtgt ttacctatca gaaggtcttc cagatttgat
     6241 ccgtgtgacg actgtgacct tgatttccct tgttggggaa acagctatgg ccggtgcggt
     6301 tggagctggt ggtatcggta acgtagccat cgcttatgga tttaaccgct acaatcacga
     6361 tgtgaccatc ttggcaacca ttattatcat tttgattatc tttgcaatcc aattcttggg
     6421 agatttcttg actaagaaat tgagtcataa ataaaaagag ccgcgtggct ctttttaact
     6481 gatcagattt tctgggcaaa ttttttactc aaggcttgtc caatcaaggc acccactagg
     6541 gctccgatga caatacttgc gataaataga aggacagttc cagggtttgg agcgaccatg
     6601 atacggtcga tatattcttg ggattttcct cttgccagaa gagtagccat ataggctttg
     6661 ggcgcaatcc acataagcaa gattggtcct gttgtactaa aggcgaaaat aatgaaagaa
     6721 aggaagttct ttgttttgtc cttgtatttt cctaaatgag ctactccatc tgctaggagg
     6781 ccacagataa ttccaggaag gaaggaacca gcaccgtgtt tagttcccaa gaaaaagagg
     6841 gcaatgacaa ggccgatagt ggtaatggct ccaaagtgcg gaacttttgc gactaggatc
     6901 atatagacgc taccgccgac aagggcagta aaggcaggcg cataaaacat gtttccagtt
     6961 tggtcaaaga gattgcccaa aaggacacca atccccatgc agaggaagta aagaactgca
     7021 aaaagcagtg tagttaagat agatttcttc atgaattgtc tcctgataat tttttcacaa
     7081 ttctcatttt accatggttt ggtgggattg taaatggata ctagaagttt ttgaaaacgc
     7141 ttgaaatatg atataatggt ttcatagtta tttttagggg aatatcatgg gtagattttt
     7201 agactttgtc tttaatcgtt tctttttagg gatgattgcg acagccttct tttggctatt
     7261 aactttagca ggagggatta tccttggtct agcgccggct agtgccacct tgatgagctt
     7321 atatgcagaa catggttata gctttcggga atacagtttg aaggaggctt ggtctcttta
     7381 caagcaaaat tttgtctcaa gcaacctgat tttctatagc tttttaggtg tgggtctagt
     7441 tttgacctat ggtttgtatc tcttggtgca attgcctcat cagaccattg ttcatttgat
     7501 tgcgaccctt ttgaatgtcc tagtagttgc cctgatcttt ttggcttata cagtatcttt
     7561 aaaattacaa gtttattttg ccttgtccta tcgaaatagt ctcaaattat ccttgattgg
     7621 catctttatg agtctagcag ctgtggccaa ggttctcctt gggactgtgc tacttgtagc
     7681 aattggttac tatatgcctg ccctgctatt ttttgtagga attgggatgt ggcatttctt
     7741 tatcagtgat atgttggaac ctgtctatga aatcatccat gaaaaattgg cgacaaaata
     7801 gaatgaagca cttttggcta catacgcttc taagaaccta tagttcagtg atgatcatta
     7861 tcattgcgag ttttgcaatc ttactctctt acgctgactg ggattcacgt gaaaaggaag
     7921 cccagagagt agcccagcgt gtaactgcta gaacagtgag tgaaattgaa tattaccata
     7981 gagagtcaac ccagatagct caggctttag ttgaaaatca agctcgtatt gagggaatct
     8041 ataaatactt tagccttagc atgccagact atttttactg gcaattagag cggaaagctt
     8101 cgccttatat atcagtctct ctgtatgaaa atgttgatga cctctatgtt cgaaatgatt
     8161 ttgtaactgg agtggccatt gcttttcaag attacaagga agtctatgtt tctactaaag
     8221 acaaacgtag tggagaaaaa atcagggctg aggatttcaa accagcagga aatagttttg
     8281 ccattccagt gtcagatcca gtgtcagatc aagacttagg agtgatttac atctccttgg
     8341 atcctgctgt tttataccat gccattgata atactagagg tcatactccg atggcagtaa
     8401 cagtgacctc accttttgat acggagattt ttcatattgg tgagacagtt gataaggaga
     8461 gtgaaaattg gctagttggc ttaacttctc atggttatca ggttcaggtg gcagttccca
     8521 aaaactttgt tttacaagga acggtgacca gctctgcttt gattgtgggc ttgagccttc
     8581 tctttattgt cattctttat ctgactttga ggcagacctt tgctaattat caaaagcagg
     8641 tagtggattt ggtggattcc atccaagcta ttgcccaagg acaagaaggt cttcgcattg
     8701 atacgcttga aaaggatcag gaattgctcc taatcgcgga gacgaccaat gatatgttgg
     8761 atcgattgga aaagaatatc catgatattt accagttaga actcagtcaa aaagatgcca
     8821 atatgcgggc cttgcaggcg caaatcaacc ctcacttcat gtataatacg ctggagttct
     8881 tgcgcatgta cgcagtcatg cagagtcaag atgagttggc agatatcatt tatgaattca
     8941 gtagtctctt gcgtaacaat atttccgacg aaagagagac cctcctcaaa caggaattag
     9001 aattttgccg taaatacagc tatctctgca tggttcgcta tcccaagtcc attgcctatg
     9061 gtttcaagat agatccagag ttagagaata tgaagattcc caagtttacc ttgcaaccgc
     9121 tggtagaaaa ctatttcgcg catggtgttg accacaggcg gacagataat gtgattagca
     9181 tcaaggctct taaacaggat ggttttgtgg aaattttggt ggtcgataat ggtagaggaa
     9241 tgtcggctga aaagttggca aatatccgag aaaaattaag tcagagatat tttgaacacc
     9301 aagccagcta cagtgatcaa aggcagtcta tcgggattgt caatgtacac gagcgttttg
     9361 tgctctattt tggagaccgc tatgccatta cgatagagtc tgcagagcaa gccggtgttc
     9421 agtatcgtat tacaattcaa gatgagtaga aagggagaaa atgtataaag tattattagt
     9481 agatgatgag tacatggtga cagaaggtct gaagcgtttg attccctttg ataagtggga
     9541 tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct ctagaatatg ttcaggaaaa
     9601 tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac aaaacagggc ttgatatgat
     9661 tcgggagatg aaagagatct taccagatgc tgcctatatc ctgctctcag gttatcagga
     9721 gtttgattat gtaaaaagag caatgaacct tagtgtggtg gactatttgg tcaagcctgt
     9781 tgataaggta gagctgggaa atctgctgga gaagattgca ggtcagctcg gcgagagagg
     9841 gaagaaaagt cagactctta gtcaagaatt agacgaggct ggatttgtta gttatttagg
     9901 ggataaggag aattggtgga taggtctatc caaggaaaaa caaggttcct tcgccattcc
     9961 ctactatgtc ttgggccaag actggcagat tttcatttct gaccaacccc tagatggttt
    10021 agtcgttaca ccttttgaag ctccttatca agaacacttt gaacgttgga agctgaatgc
    10081 tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag tctgagagtc tctttgccta
    10141 ttacgaaccg atttataggg ttatcattca gggaaatctc aatcaaatcg tagaagagtt
    10201 aaatctcttg gagaaggtag ttcttgaaaa tacacctcgt gtttcgatta ctaaacagct
    10261 ttttatccag tttgtcatgg atgttttcca tttatttgaa catctcaaag ctgatgatat
    10321 gacggacatt gtcaaaacca ttcatgctat tcaatccttc gatgaattgg tttcttatat
    10381 caaggaaact ctgatcagct ttttcgatca ataccgtatg aatgaaaatg tggtcagtgt
    10441 gctggaagtc attggtcgtg attaccaaaa agagctttcc ctcaaggata tcagtaaggc
    10501 cctctttatc aatcctgtct atctagggca gttgattaag cgtgaaaccg attcgacctt
    10561 tgcagagtta ctaaataaac aacgtattaa ggctgcccag cagctcttgc tttcaactag
    10621 tgacagcatc gaagatattt gttatgctgt tggttacagt aaccttggat atttctataa
    10681 agttttccga aaattgtgcg gaaaatcgcc aaaagcctac cgaaaacagg tagaaactat
    10741 actataagat ttgtattcct ttacaaaagg tgctataata ttatcaggag gtcctatcat
    10801 gaaaaagaaa ccaatttatc tatgggtttt gctaatcttg tctgccctta tttcagttcc
    10861 gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa gcccttcgtg ctgctcagaa
    10921 acaagttgca ggggtcaatg ctcagcaatt agaagaccag cttaattata cctatagagt
    10981 agcagaagca tctcattcta tttttaatgt tgctttgatt gtgctatcta ctattttagt
    11041 ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa tatgcaaact atacttacgt
    11101 tggctatgtt ttgttagcta ttattggttc gatttatggc tatgttggtt tacaagacgc
    11161 tgtgcagttg gttcaagatg agagcatgcg tttgacagtg agtattggtt caaaagctgt
    11221 tagcattttc tatatcgtca tcaatgttct cttcctagcc cttgtcttct ataagatgtg
    11281 gcgacaacag aaagccttgg cagaagaaga ggaaacagaa gagcttacct aagtattgac
    11341 aaaaaagaac tatcaagata caatcttggt agttgttttt tgattataga taaaatcatg
    11401 gaggtacata tgaagacaat ttctttagtt tatattagtt tgagtggcaa cactgaaagt
    11461 tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca aagggattga ggttcaaaag
    11521 attcatatca aggatttggt caaggaaggc aaaaatttct atgaaatgga ccatccctat
    11581 gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg tggataacgg agatgttgag
    11641 attttgacga caccggtggg agattttatt gcctatggta acaatgctag taagtgtttt
    11701 ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat actgcctaac agccaagcaa
    11761 tacagtcaac gctttggctt ccctgtattg gctgactttg aaatgcgagg catgctggaa
    11821 gatatcaaac atgtcgcagc tattatcgca gatttgtatg agttggaaaa ggagaattaa
    11881 tactcaatga aaatcaaaga gcaaactagg aagctagtcg caggttgctc aaagcacagc
    11941 tttgaggttg cagatagagc tgacgtggtt tgaagagatt ctcgaatagt ataaagttct
    12001 tataagaggt ggttgaagtt gttcaactgt tttttgagta taaacagtct ttaagaacgt
    12061 aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat gctttttatc atagaaatat
    12121 ttgctgaatt ttctcttgaa atgaaacctt atcttcatct cgcgcttgtc ccttaccctg
    12181 cttttccgat tgcgagtgcg tagataaaga agatggcgaa gccaaagagg aaaatcaatc
    12241 ccgcaatggc aaggtgtttg agccaagaag gaagattttt gttttcacgc gttaccaagg
    12301 cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga gccaatcatg gcaaagcgga
    12361 gcatggttga aacctgacca gcgaagaact tgataatgac gataccgatg atagcagtga
    12421 tggtcatcca gatgttcaaa gatttacgat tgtcctcttt ttgactgatt agcagtcgga
    12481 gagattcctg attaacgcga gaatagccat cgataacagt tataactgtt ccaaagatac
    12541 agaggaaggc aataaaggta atcaagtaac gggaccattc gccaagaaca gaggcataca
    12601 tgcccacgaa ttgagagatg tatttggctg aagcagcttc aaccgcctgc cctgtaggat
    12661 actgaatcag tgctcccagt gccacaaaga agacggctag gatagctgtt ccaatataac
    12721 cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt gacggtcttt ctcttttcag
    12781 ctgaccaaag tgaattgatg gctgaaattt caataggagc cggcatccat cctaggaggg
    12841 agacgatgaa gggcagagct gccatttgcc aaggtgtctt ctcgacaaaa tcagaactgt
    12901 attctggatg cttgaccgcc gcaatgataa ctgcaagaac agtcgcaatg gttaaggcag
    12961 acataatcca tttgaccatg ccgtctaaaa gtttgtagcc tccaaagagt agcatagccc
    13021 aaatgattgc aacgagaatg agggaccact gagtaatgct aagtccaatc attgggaaag
    13081 cactggcgat gatagctgag cacagaatgg caacaccagc cgtgttgacc atagccgaaa
    13141 agacattgag gataaagaaa atccagagat agagttttcc tttttcggca taaccttcaa
    13201 ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa acggaaaaat ggatatttaa
    13261 agacattggc taagatgacc aagagaagta gagaccaacc gtaagaaccg ccagcttgag
    13321 ttgaggatac aatgtgggaa cctccaacag cggcagttgc cattaggatt ccaggtccca
    13381 ttgcttttag cttgcttgcc caggttgatt gatttaagga aatagcttgc gacatgataa
    13441 atactccttt ttgaattttc agaataatct gtatatgtaa tctatattct acaaaaaatt
    13501 ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat ttacaaagaa aatctgaaat
    13561 gaaagttcta taatgaagtt agccacctta ccttagtcaa gaattagatg tttcactatg
    13621 tttgagtaag ttgatgattt catttgataa caggtttgaa actgttaggc taggtggcca
    13681 aggctaatca tagccttggt ttagctgaaa aaacaggttc aagggttcct gttgtcaaat
    13741 gaaatgtgat ttaaggtata agaaaacacc tctgtgctat acttgttgtt caccacaaac
    13801 acaaggaaag gcacagagat gcaagaacat tataccccaa aagggaaaca tttgacaata
    13861 gataaccgtc gcttgattga gcggtggaag aataaaaata agtccaatcg tgaaattgca
    13921 ggcttgttag gaaaggcgcc tcaaacgatt catactgaag tcaaaagagg tacaacttta
    13981 caacaagtga gaaaagggct atacaaaaag gtctattctg ccgattacgc acaaactgtt
    14041 taccaattca atcgaaaacg gtcggtgaaa aagttaattt taacaaagga aatcagagag
    14101 aagatcttac actatcataa gcaaaaattt tcgcctgaaa tgatggttaa caagaagcaa
    14161 gtgaaagttg gtatttcaac catctactac tggtttcata atggtcattt aggattgacg
    14221 aaggccgaca tgctttatcc cagaaaaagg aaaggtgtca agaagcaagc tagtccgaac
    14281 tttaagccgg caggtaaatc tatcgaagaa cgtcctgacg ttattaatct tcgcttggaa
    14341 aatggtcatt atgaaattga taccgtccta ctgactaaga taaaaaatta ttgcctgtta
    14401 gtcttaaccg accggcggag cagacaccaa attataaggt taattccaaa taaaactgct
    14461 gaatctgtca atcaggcgct tacgttacta ttaggggagc atcgtattct gtccattact
    14521 gcagataatg gttcggagtt caaacgattg tctgaggtat ttcctgagga acatatctac
    14581 tacgcacatg cttactcttc atgggagaga ggttcaaatg aaaatcataa tcgattaatt
    14641 cggagatggt tacctaaagg aaccaagaaa acgactccga aagaagtagc ttttatcgaa
    14701 aattggatta acaactaccc taaaaaatgc ttggactaca agtcgccaag tgaatttctt
    14761 ttgggtggct aacttcaact tgaaatttgg gagaagatct gaaataactg ttatgatata
    14821 gcggattgaa actagaatag tacacctctg cttctaaaac attgttagaa atcgatttga
    14881 ctgtcctgat cgatttatcc tgttcttatt tcatttcact atagtaaggt gcagcaggat
    14941 aaagaaaaac cgagaagttt ctttctcgga tttgcttatt atgaggttcc tattttctat
    15001 gctccaagag ttgattgatg tgatctactt ttttagcctc tcttttatag agaatagccc
    15061 agatgatgag atagacaatc gcaaactcga taatgagctg gaggtagaaa atccagtgga
    15121 aagggaacca accagcaaga gttgctagtg ggacaaagcc agccagcata aggaagaaat
    15181 gagtcagagt ggcacgaagc atgctccagt cacggctgaa taagcggttg ccaaagttga
    15241 agagcatacc gatggctgcc cagataagtg tgcagtagag caagaccagg gcaccgtgaa
    15301 cctgatgctg atccatcact tggccgatga gagagtaggg atttagtggt gcgtaggtat
    15361 ttggtgcata aatgagtgaa aagaggatgg agaggatgag gccgataaga acaccggcag
    15421 ctgcatcgtg aaatacttgt tttttcatag ttctaatttc tccttgatgg tttttagata
    15481 acggcgtgaa gagtaggtga agctttcgtt tttcaagaaa atttctacca gaccgtttgg
    15541 cgtgagcttg aggtgagaga tggaatcgat attgatgatt tctgattggg aaatttggat
    15601 aaaattgctt ggcaagagtt taagaacctg atagagtcgc aaatcaatgc tgtaggtctg
    15661 actcgcggtt tctgctagaa ccttccgatt ctcgatatag aagcgctgaa tcttgccaat
    15721 ctcaactaga tagacctgat catcgatttt tcctttgatt ttttctcttt ggtccagatt
    15781 ttctgcgaac tcgatgactt tctggacttt ttcggtttct tgaggtgctt ggacaatcag
    15841 cttttcctcc tcgtaagtct cactaatctg tagttctact ttcataaatt tctctccttg
    15901 tttttcatac aaaattaatc tcacttcttg tacaccttta ttaatactct tcaaaaatct
    15961 cttcaaacca cgtcagcgtc gtcttgccgt aggatagttg ttgactttgt cagttttatc
    16021 tacaacctca aaacagtgtt ttgagctgtc tgcgtctagc tttctagttt gctctttgat
    16081 ttttattgag tataccacta ttttactccc tctggcaagg gactttgtct atgtggaggg
    16141 attgggctcc tatgtggtgg agtttttctg ttctttctga aatatggtat aatagcacta
    16201 attaatttct aggaaaatag atacagaaag gggctgaaag atgtctcata ttattgaatt
    16261 gccagagatg ctggcaaacc aaatcgcagc tggggaggtc attgaacgtc ctgccagtgt
    16321 ggttaaagag ttggtagaaa atgccattga cgcgggctct agtcagatta tcattgagat
    16381 tgaggaagct ggtctcaaga aggttcaaat cacggataac ggtcatggaa ttgcccacga
    16441 tgaggtggag ttggccctgc gtcgccatgc gaccagtaag ataaaaaatc aagcagatct
    16501 ctttcggatt cggacgcttg gttttcgtgg tgaagccttg ccttctattg cgtctgttag
    16561 tgtcttgact ctgttaacgg cggtggatgg tgctagtcat ggaaccaagt tagtcgcgcg
    16621 tgggggtgaa gttgaggaag tcatcccagc gactagtcct gtgggaacca aggtttgtgt
    16681 ggaggatctc tttttcaaca cgcctgcccg tctcaagtat atgaagagcc agcaagcgga
    16741 gttgtctcat atcattgata ttgtcaaccg tctgggcttg gcccatcctg agatttcttt
    16801 tagcttgatt agtgatggca aggaaatgac gcggacagca gggactggtc aattgcgcca
    16861 agcaatcgca gggatttacg gtttggtcag tgccaagaag atgattgaaa ttgagaactc
    16921 tgacctagat ttcgaaattt caggttttgt gtctttacct gagttgactc gggctaaccg
    16981 caattatatc agcctcttca tcaatggccg ttatatcaag aacttcctgc tcaatcgtgc
    17041 tattttggat ggtttcggaa gcaagcttat ggttggacgt tttccactgg ctgtcattca
    17101 catccatatc gacccttatc tagcggatgt caatgtgcat ccaactaagc aagaggtgcg
    17161 gatttccaag gaaaaagaac tgatgaccct ggtttcagaa gctattgcaa atagtctcaa
    17221 ggaacaaacc ttgattccag atgccttgga aaatcttgcc aaatcgaccg tgcgcaatcg
    17281 tgagaaggtg gagcaaacta ttctcccact caaagaaaat acgctctact atgagaaaac
    17341 tgagccgtca agacctagtc aaactgaagt agctgattat caggtagaat tgactgatga
    17401 agggcaggat ttgaccctgt ttgccaagga aaccttggac cgattgacca agccagcaaa
    17461 actgcatttt gcagagagaa agcctgctaa ctacgaccag ctagaccatc cagagttaga
    17521 tcttgctagc atcgataagg cttatgacaa actggagcga gaagaagcat ccagcttccc
    17581 agagttggag tttttcggac aaatgcacgg gacttatctc tttgcccaag ggcgagatgg
    17641 actttacatc atagatcagc acgctgctca ggaacgggtc aagtacgagg agtaccgtga
    17701 aagcattggc aatgttgacc agagccagca gcaactccta gtgccctata tctttgaatt
    17761 tcctgcggat gatgccctgc gtctcaagga aagaatgcct ctcttagagg aagtgggcgt
    17821 ctttctagca gagtacggag aaaatcaatt tattctacgt gaacatccta tttggatggc
    17881 agaagaagag attgaatcag gcatctatga gatgtgcgac atgctccttt tgaccaagga
    17941 agtttctatc aagaaatacc gagcagagct ggctatcatg atgtcttgca agcgatctat
    18001 caaggccaat catcgtattg atgatcattc agctagacaa ctcctctatc agctttctca
    18061 atgtgacaat ccctataact gtcctcacgg acgtcctgtt ttggtgcatt ttaccaagtc
    18121 ggatatggaa aagatgttcc gacgtattca ggaaaatcac accagtctcc gtgagttggg
    18181 gaaatattaa aagtataaaa aagtctggga aaaattttca aaatcagaaa aacgcataaa
    18241 atcaggtgtt caaaaacctt gattttatgc gttttatcat agaaatattt acttcatgtt
    18301 ttcctaattc ttttcgaaac tctttttaaa ccacgtcagt tttatcagta atctcaaaac
    18361 agtgttttga gctaattttg ccagttttgt ctgtaacatc gaagttgtgt ttgaccactc
    18421 tgcgactggt ttcctagttt gctctatgat tttcacagag tattaaattg cgattttgcc
    18481 aagtttcttt attcgtctaa aagtagagtc tgttctatgc gtctaatgta cgaattaggt
    18541 tgaccatttc aatagctcct tgtgcacact cagaaccctt atttcctgct ttagtgccag
    18601 ctcgttctat ggcttgttca attgtatctg tcgttagcac accaaacata acaggaattt
    18661 cgctatttaa actgatttgg gcgattccct tagatacctc gctacataca taatcataat
    18721 gacttgtatt ccctctaatg acagctccca agcagataat tgcatcatat tttttacttt
    18781 ttgccatttt tgatgcaatc agtggtattt caaaagctcc tggaacccag gctacctcta
    18841 tatctttctc gtttacattc tctcttttga gattatctag tgctccagat aataattttg
    18901 aagttataaa ttcattaaat ctcgctacaa caatacctat tttaatattg tttgctacta
    18961 aattaccttc ataagtgttc atttattttt cctccatatt taaaatgtga cccattcgat
    19021 ttttctttgt ttctaaataa aaactatcgt aaggattggc ttctatttcg attgatattc
    19081 tactggaaat ggtaattcca tatttttcta actgttcaac cttgtcagga ttatttgtca
    19141 gtaaatgaag tgactgaagt cccagatctt taagcatttg tgctccaata tgatattctc
    19201 ttaaatcacc ttcaaagcct aatgcaagat tggcatcaag cgtatccatg ccttgatctt
    19261 gtaaatgata ggcttttaat ttattgataa gtccaattcc tcgtccctcc tgtcgcaagt
    19321 aaagtaagac acccgaacca ttctcaacaa tcattttcat agctttatcg aattgctgtc
    19381 cacaatcgca acgtaaagag cctaaaacat ctcctgttaa acattcggag tggacccgac
    19441 ataatacatt ggcttcatcc tctatgtttc ccataataag agcaagatga tgttccccat
    19501 ttagtttatc tatatagcta attgctttga aattaccgta tctagtaggc atattgacag
    19561 ttgaaactcg ttctaccagc tgatcatata cttttctata ttcttgtaat tctttgatgg
    19621 taattagtgg aatgttgtgt ttcttcgaga actgaattaa atcatctgtt ctcatcattt
    19681 tgccatcatg attcattatt tcacaacata ggccacactc ttttagtcca gctaatttta
    19741 ataaatcaac agttgcttct gtgtgtccac ttctttctag aacaccacct ttttttgcaa
    19801 ttaaaggaaa catatgtcct ggcctgcgaa aatcagaggg tgttatatct tcagctacac
    19861 acatacgtgc ggtcagtcct ctttcctcgg cagaaatacc tgtggtcgtt tctttataat
    19921 caattgaaac tgtaaaagca gtcttatgat tatctgtatt gttttcaacc ataggtgaaa
    19981 gcattaattg attagctaaa ctttcgctca taggcataca aattaatcct ttggcataag
    20041 tagccataaa attaacattt tctgttgtag ctgcttgtgc agaacaaatt aagtctcctt
    20101 cattttctct atccttgtcg tctataacaa gaacaagtcg tcccttctgc aatgcttcta
    20161 atgcttcttg tatttttcga tattccattg actgattatc ctttctgcta aaatccattt
    20221 tgatataata gttccttaga tatttctgat tttggagagt tatccatcag tttttgcaca
    20281 tatttaccta agatatcatt ttcaagattt actgtactcc cgacttgttt actcttaaga
    20341 atggtttgtt tcaaggtatg agggataaca gatactgaaa agtttacttt ggagacttta
    20401 gcgacagtca gactaatgcc gtcaattgta atagatcctt tttcaactat taaatctaaa
    20461 atttcttttt gtgtgttgat ttgataccat acagcattat catctttttt tattgacgag
    20521 atttttcctg taccatcaat gtgtcctgta acgacgtgac ccccaagtcg accgttgaca
    20581 gataaggctc tttctagatt cacctcactt ccatgtttta atagagtaag agctgttcga
    20641 ctccatgttt cattcattac atcaactgta aaggattgat gattgaaatg agtaactgta
    20701 agacagatac catttactgc tatactatcg cctaaatgga tatccgttaa tatttttgag
    20761 gctttaattg atagtttaca attacgagag tctttctgta ttctttcaac ttttccgatt
    20821 tcttcaatta ttcctgtgaa catggataaa tcacttcact ttctatgaga tagtcatttc
    20881 ctatttgaga aaaagcataa ggtttcaatc taatagcgtc atttggcaaa gaaatgcctt
    20941 cacctccgac aggaaacttg gcactgcctc caaaaatttt tggtgcaata tatattttca
    21001 gctcatcaac aatttgttgt tccaaagcac tccaattcat tagactgccc ccttctagaa
    21061 ctaggctatc aatctgcatg tttcctagat gttgcattaa actcgataag tctatatgat
    21121 tgcctttttt ctttatggaa agtatttcac agccatgatt ttgatatagc ttcattttat
    21181 ttttgtcttc agaggaagtg gcaatgtaag ttttaatatc atttgctgtt tttacgattt
    21241 tagaggtaag aggagttcgt aaatgtgtat cgcatatgat acggatagga tttttccctt
    21301 cctccaatct acatgtcagc aaaggatcgt cttgaataac agtattgact cccaccataa
    21361 ttgcactaac atagtgtcgt aactgatgca catgctttct tgcttcttct tcagtaatcc
    21421 atttggattg atttgtttta gtggctattt ttccatccat tgacattgca tatttcataa
    21481 aaacataggg tacatgctgg gtaatatact ttctaaaact ttttattaag ttaagacact
    21541 cattttctaa aattccaaca gtaacttgaa gattattttc ctcaagtatc tttactcctt
    21601 ttccagatac aataggatta cagtctaggc ttccaatgac tactcttgta ataccactat
    21661 cgattatagc atctatacag ggaggtgttt tcccgaagtg acaacagggt tcaagtgtta
    21721 cataaagcgt cgctccgaca ggggattctc tacagttttt aagagcattt ctctcagcat
    21781 gtgggccacc aaaaaactca tgataacctt gtccgatgat gtgattatct tttacaataa
    21841 ctgcgccgac cataggattg ggattgacgt aaccagcccc tttttgtgcc agttttattg
    21901 ctaatttcat atattttgaa tcgctcatct cactacctcc aaaaaaatat accttgaata
    21961 ggggactact caaggcatac aaaagaaaac ttatgcgatt aacaaaaatg ctctgaaatg
    22021 acaagtaatc atttcagagc acgcaaaaag cacaaatata cttttatctt ctttcatcca
    22081 gactatactg tcggctttgg aatttcacca aatcatgcct ttcggctcgt gggctatacc
    22141 accggtaggg aattgcaccc tgccctgaag atagttattc aattacagat gattatagta
    22201 cttaattttg aatatgtcaa cagataaata ccgattgttt ttgatatact gtatttgtga
    22261 taatcgattc tcgctcctcg gataaagaaa atatgatata ctagataaac gaaataagag
    22321 agaaggaaca ctatgtacgc atatttaaaa ggaatcatta ccaaaattac tgccaaatac
    22381 attgttcttg aaaccaatgg tattggttat atcctgcatg tggccaatcc ttatgcctat
    22441 tcaggtcagg ttaatcagga ggctcagatt tatgtgcatc aggttgtgcg tgaggacgcc
    22501 catttgcttt atggatttcg ctcagaggat gagaaaaagc tctttcttag tctgatttcg
    22561 gtctctggga ttggtcctgt atcagctctt gctattatcg ctgctgatga caatgctggc
    22621 ttggttcaag ccattgaaac caagaacatc acctacttga ccaagttccc taaaattggc
    22681 aagaaaacag cccagcagat ggtgctggac ttggaaggca aggtagtagt tgcaggagat
    22741 gaccttcctg ccaaggtcgc agtgcaagca agtgctgaaa accaagaatt ggaagaagct
    22801 atggaagcca tgttggctct gggctacaag gcaacagagc tcaagaaaat caagaaattc
    22861 tttgaaggaa cgacagatac agctgagaac tatatcaagt cggcccttaa aatgttggtc
    22921 aaataggagc agagaatgac aaaacgttgt tcgtgggtca agatgaccaa cccactctac
    22981 atcgcctatc atgatgagga gtggggccag cccctccatg atgaccaagc gttgtttgag
    23041 ttgttgtgta tggaaaccta tcaggcaggc ctgtcttggg aaacggtact caacaaacgc
    23101 caagctttcc gagaagcctt tcatagctat caaattcact cagtcgcaga gatgactgac
    23161 actgaattgg aagccatgct ggagaatcca gctatcattc gaaatagagc caagattttt
    23221 gctacacgcg ctaacgccca agcctttcta cagttacagg cagagtacgg ctcttttgat
    23281 gcctatcttt ggtcttttgt tgaggggaaa actgtcgtta acgatgttcc tgattatcgc
    23341 caatccccag ctaaaacacc cttatctgag aaattagcca aagatctcaa aaaacgaggc
    23401 ttcaagttca caggcccagt cgccgtattg tcttttctac aggctgcagg gctagttgat
    23461 gaccacgaga atgattgtga gtggaaatgt cttaaatgat gtctaacaaa aataagggaa
    23521 ttctgatttt tgtgattctc tatacagtcc tctttgtgtt tgatggcgtt aaattgctgg
    23581 cttctttaat gccatctgcc attgcaaatt atcttgttta tgtagtttta gctttatatg
    23641 gctccttctt gttcaaggat agattgatcc aacaatggaa ggagattaga aagactaaaa
    23701 gaaaattctt ctttggagtc ttaacaggat ggctctttct cattctgatg actgttgtct
    23761 ttgaatttgt atcagagatg ttgaagcagt ttgtgggact agatggacaa ggtctaaatc
    23821 agtctaatat tcaaagtacc tttcaagaac aaccactact gatagctgtt tttgcttgtg
    23881 tcattggacc tctggtagaa gaattatttt tccgtcaggt cttattgcat tacttgcagg
    23941 aacggttgtc aggtttacta agcattattc tggtaggact tgtttttgct ttgactcata
    24001 tgcacagttt ggctctatca gagtggattg gtgcagttgg ttacttaggt ggaggccttg
    24061 ccttttctat tatttatgtg aaagaaaaag agaatatcta ctatccccta cttgttcaca
    24121 tgttaagcaa cagcctctcc ttaatcattt tagctatcag tatagtaaaa tgaaatgaga
    24181 acaggacaaa tcgatttcta acaatgtttt agaagtagag gtgtactatt ctagtttcaa
    24241 tatactgtaa tatgtgatga aaatgccagt aatgataccg agaaaaaagc tgagaaactt
    24301 ttcccagctt tatttgttat agtcaaagag aatgacttgt tcctgtgcat ctacatgagc
    24361 atggacccca aagggtacaa ttgctcttgg agttgcgtgg ccgacattca gattatagac
    24421 aatcgggata ttgctgtcaa tgatatccaa tagtgcctct ttatagtcgt catggaaagt
    24481 ttcatccata ggttttccga ccaagagtcc attgatgacc gcgaatatgc cagtgtcctt
    24541 taaagttagc aacatctttt tgaagtcttc tggcttaggc ttttcttcgc ttgtttcgag
    24601 caagaggatt ttcccttccc agtctgacaa gtcagggaaa agtttgtatt tttggcagag
    24661 ttccgtgcta tctgcgtatc gagagttgtc aaagatatcg tagagggatt cgaggcaacc
    24721 accgaggatt ttcccctcga actgggcact tccttgcaac aagtcaaaac ctgtatttgt
    24781 atgactgaca cgaggtgttc ccagggccgt gggactaaaa tcagttcgtt cctcatacca
    24841 aacgtcacta gggcggattt ctgaaattct tcccgtctca atcaattctt taaagtagtg
    24901 aaggctatag gctagcattt ctttgtctaa ttcacaaatg tctgctaaaa aggattgacc
    24961 ataaaaagtc ttgattccta atttatgcaa catgaggtgg ttcatggttg tatccgagaa
    25021 gccaagaaaa attttttgtt tgataacctt ttggagttgg tcattttcaa aaagataagg
    25081 tagcaagcga taggcatcgt ctccaccgat ggcacatagg atcatgtcga tgctatcatc
    25141 agaaaaggca tgaatcaaat cctctgcacg agcttcagga tggtccttga taaagtctaa
    25201 tccttttaac gaatggggca aaaagatggg attgagtccc agatccttga gacgttggat
    25261 acccaagtcc acttcgtgtt tgacaaaatc ctctccgata atgccactag ataaactaac
    25321 aataccaata gtagaaacca tatctcatcc tcctagaaat agattgagcc tattttatca
    25381 caaaatataa gagaaagcta tgtgggattt cagaagaata cttttaatac tcttcgaaaa
    25441 tctcttcaaa ccacgtcagt tttatttgca acctcaaagc tgtgctttga gcaacctgca
    25501 gctagcttcc tagtttgctc tttgattttc attgagtata actcaaaaaa gtaagtgaaa
    25561 aagcaaccgc acctgcagtt gcttttatcg ttttcttatt cttgatagcg tgttggtcct
    25621 gcacttgcac tacggatatt caagcgtttc ttgagataga agcgaagggc taggagggct
    25681 actccaataa tagctagtgg caatggatcc agtactgggt taaggctagc tggtaggaag
    25741 cttgttgcaa agaagacaag caaccaaagg aacatagaag ctaggataac tagtacagat
    25801 ttccagaaag gtggacgttg actgcgatcc atatctggtc catagtattg gtaaacaaag
    25861 tagtacatca agtagaaggc aaatccacca accagtccaa ctaatagaag agtaatcaat
    25921 ccatagccga aagcttgatc tgccgcaaag aaggttgtga gggcgctgac aagggcaaag
    25981 aggctagtga tgaaaagagc tgagtccata atcatcagtt ttggatcatc attttctttt
    26041 ggatgctctt tttcgtactg ctctttgaca gtgaagctat gagcccaatg agttggtgcg
    26101 ccgtataggg aacgggcagt tgtaccttta gattgctcct caaggatttg gggaatgact
    26161 tcctcaaaaa tagtctggat ttcagcgtct gttttcccat ctttgatgaa ttgttgggta
    26221 gcaatgtgaa caaactcttg gtttttctta gttaattttt gtagatcaat ttgagacata
    26281 ggaactcctc ttagaaccat tttttatgga tgagatagag agtgagcgag acactcatag
    26341 caaaggcgat aaagacgatt aaccagaagg catttggctc tccgtttagg ggaatttcat
    26401 tatccttaaa gttcatcccg taggcagaaa agaccatggt tgggatggac atgacgatgg
    26461 tcacaagggc caaggttttc atgatgttgt tctggttgtt agaaatgata gaggcaaagg
    26521 tctctgtcat agaatgcaag acgtttccat aaatatctgc catctcgatg gcctgttggg
    26581 tttcaatcag ggtgtcttca agcaggtctt cgtcctcaag gtatttcttg atattgctgg
    26641 ttgaactggt caatttctta atcacgcgct catttgtttt gagggaggcc ttgaaataga
    26701 cgatagtttt ttccaattcc atgagctcaa tcaattcttc attacgagtt gattgatgca
    26761 gttgactttc gatttgttca ctcttgcggt cgattgaacg aagggctgtt aggtaaagct
    26821 ctgcattgcg ataaagaatt tgaaagataa aacgtgaacg catgaaggta tagaaattac
    26881 gcaatcgacg gttgataaag acatcaagga caggtagtgg ttccaaacac gtagtgataa
    26941 tggtttcctc agtgatgata ataccaagcg ggatggttac gtagtaggtg cggttatttc
    27001 tttcctccgt gaccggcacg tctacgataa tcagggtata ctcgtcttca atggtaatac
    27061 gagacatttc ttccgcatcg agcggtgctc gaaggtcggc aatatcaata tcgaaggtgt
    27121 tggcgatttc gagtgattca ttttgagtcg gattgacgag attgatccaa gtacccggtt
    27181 caagcgtatc gatctcttta aattcagttg ttgtagagag aaaaacttgt ttcatatccc
    27241 ttatcctttc tcatttttca gattttttca cactgtacta ttatactaca aaatcggctt
    27301 ttttcaaata aaatcttaca aagacaccgt tgttattgga tttttacttt gtcttgaaat
    27361 gttgattttt aaatttgctc ccctttttgc tccccctata gtgcttttag tgcagtttcg
    27421 tagaatgata ctgctttttt tgcgttctct tttgagaggt gactatatat atccatggtc
    27481 attgataaag tggaatgacc taggcggtac tggagttcct tgtatggtat tccagagtta
    27541 agcaagagac tagcgtgagt gtgacggaat ccgtgaaatc caatgttagg aacatcagca
    27601 cgcttaaaat gtgtttgcaa tcttctttta agtcttgaac tgctaggata ctcatgaatg
    27661 aaatcagaaa ataccacgcg ttcacgttgc cctatcttcc aggcctcttt agtttggcgt
    27721 agtttgtact gcttcagcat gctaacagtc gcttgatcta tatctatatc ccgataacta
    27781 gccttagact ttgggctatt gatttctata tcccgattta gtgttttggt aatatgcaca
    27841 acggcattat ctaagtcaat atcagaccag gaaagagcta aagcttcatt gatacggcaa
    27901 ccagtagcca ataggaactt atagagtgtt gtctcatagt agtaacgata tctatgagta
    27961 tctaaattat cgagataacc aagaaatttt tttagttctt gattttcaaa gtgctttact
    28021 tttttccgct ttgctttctg agtgttacga ggtaaaacaa catcacgcgc aggattggac
    28081 ggtatagcct gcatggttac gccatactgt aagatacgtt tgtttaaagc gtgtatcttg
    28141 tcataatgta gaaaagccgc tttttcccct ctattagtct tgtcagcaag ttcgttgata
    28201 attgactgga taagtggagt agtgagctta tcgagcttgt aagccccaaa aataggcaat
    28261 atatgattat cgattagctt tttaacattg ccttgagtgt ttggcttaac cgtattctta
    28321 taactttcca accagagagt tgccaattct tgatagtttt ttatggtaac agccttttgt
    28381 ctggtagatc ctgctttttg aaaagctatt ttttcttgat tggctttctg cttaacttcc
    28441 ttttgtgtcc gacctgttac tttggttttt actttctttc ctgttacctg gtcaactcct
    28501 agatatacat tagcacgata aactttgcta ccgtcttttt ttataacttc agttattttc
    28561 atgatgataa acctttctaa aatacatcag caggcaagcc attatcaaaa aggttttata
    28621 tcatgctagg agctacgaga acccccttat tttcgtttta tttcttccag taaagaatac
    28681 atagcattaa tgtggttata tttttgaaat tcaggatctt ggttttgtgt aataaagtat
    28741 acgtattgtc taccagattt gaatttatcg atagcttgtt tttccactaa tttttttaaa
    28801 tattttaaaa ttgtattttt gtggattttt agtttttctt ccaaagcctc tcttgttacg
    28861 aaacggtgtt cgattattaa ctctaatatc tttttctcat attcgttatc aatatccaga
    28921 ttatctataa gggaagtatc ccataatgta aattcaactg agtctaattc agttcgtaaa
    28981 ttgggatatt ttaaatgact ctctttaact gcttccatta ttttgggtat accagttccc
    29041 gctttttcac ataaatttaa aaatctaaaa atttcttgta ttaagtagtt tcttggatca
    29101 gaatgtgccc cactaaaaaa gtcctttatg tcaattctaa gtgttccgcc atttgtgaat
    29161 atatacctgt cgggatatct aattatcatt atcccttttt cgcttttata gtcgctatga
    29221 ataaggctat taatgaatgc ctcacgaatt gcaattcgta attttgaaat tccaattcta
    29281 ttcatagaat tttcttgaat gttagagttg tcatttaaag ttagatataa tttttcaata
    29341 actaggtaaa agaaattaaa aagattatct tccccccatg taccatcata aatcacacga
    29401 tctttaaagc gattgttttc agaaaactct tttagaacat attctacgtt atagtgtgga
    29461 ataaactctt ttattgaatt atgtgtacca aaaattaata gtccagcaac tgttggcttt
    29521 attttatcgt ccttgcgatc tcttcgtaaa gcatttattt ttattaaaaa ttgttcgtta
    29581 tccaactttg aaaaagggtg ctccgcattt atattatcaa atttttctct atatagcttt
    29641 attgtttctg tatctaagtc taaaatagaa aaatcctgaa taagtgtgct atcaaaactt
    29701 tccttagcgg aatctcttaa catagagttg atttgctctt gtgaacacct aaaatcacca
    29761 gtcccctgac gaaaataggt agatgctatg ttgtcattaa gatatatagg tttatccttg
    29821 tagtctacct tgttaacagg gataatgaca atctcttttc cttttatatt tacgacttca
    29881 acactttctt cattaatcac atttctatta attttattag ggttattaag taaactatat
    29941 aattcgtcca gtactttatc gggatcatta actccagaaa tataaaaatc tttattcttt
    30001 gtattctctg agacacctag aattaacaga ccattatttg tattagcgaa ggaacaaatt
    30061 gttttcatac cgtctttagg gaaagaattt ttagcttctt tgaattcaac accttggttc
    30121 tcccctgata ataacaattt tggtatatcg tattttctca ttttttctcc aatcaatttg
    30181 cacacgcatt cgcacacgcg cgggaaaaat agtttatttt tagttagcta acagtgctat
    30241 taaaggtttt tttgaaagta gattattcgc acacgcattc gcacacgcgc ttcaggattg
    30301 ttgaacattg tggcgcgtgg gttagtctat accccaaagt aacgcaaaat catctagatt
    30361 ttctttatct ttcttagctt cttgaagagc taaagactta atttcttcaa atagattttc
    30421 aaacttttta tataatttgt tgtaatattc ttggttgaat tccttatctt caaaaactat
    30481 gtagaattca ctacttgttt tttgaaatac aatatctagc cagaatagga tattacttgt
    30541 ctttagcgca agggcattta aaacttcata gttgtctttg ggattgtatt catttaatga
    30601 ttcagtgata gtagtgagaa actcttcagg actgattggg aaatttttac tctttgctag
    30661 ttcaattatt tccttgtctc ttttctctct ctcttttact ttctgaaaaa ttttatcttt
    30721 tgaaacattt tttacgaggt atttttcttc gtctaattgt ttatctaaca tatataaaaa
    30781 ttctttgtaa acatctttgt cagaaaagcg agggtcaaga tcagattttt tcactcccaa
    30841 ataatcagca agtttttgaa gattgccaga tgttggcatt gatctacctt ttacataacc
    30901 agttattgta cttttaggaa tttctaaagc attatgcagg tctatctgtc tgataccttt
    30961 ttctttcata acacggttaa gattattaga gaaatattct ctattcttta aatcctgagg
    31021 gctatttttt gccattgtta aaaactccct tactttaatt ctacaacctg attataacac
    31081 aaaaaagaca aagtacgaaa aaaatagaac taaatcaaaa ggaaatctaa gaaaggagca
    31141 aaccaatgga attagtctac atggacggta agaaagagcc gtatacactg agcagtattg
    31201 ttgcggagtg tgcagaagtt aagcacagac atttgaagat tttgctgaat aaacatcgag
    31261 aggacttcga gagtttcgga aaggtgcaat ttaaaatttc accttcagaa agtgggcaaa
    31321 atgtacggga ctatattttg aatgagcaac aagcaacctt gctgatcact tacttacgaa
    31381 atacagaacc cgtaaaagag tttaagaaga acctggtcaa agcattcttt gaaatgcgtg
    31441 aggagctttc taagttccgt atgcagaggg cgctagaaaa gccaaaaaga aaaaccttgc
    31501 atgacagtat agagacatgg gaggcaaaac ccaagcacgc gcatagcacc atgaacaacc
    31561 tgctactaaa agcagtaact gacatgaacg ctaagcagtt aagggaagaa cgtgggggct
    31621 ataacggtat tgatagcttg accagtgacg agctggagca ataccaggca tttgaggata
    31681 tggtaatagc catgatcggc ttgaatatga gttaccaaga aatcaaggct atggcattca
    31741 gaaataaaaa aacacgccaa agaagcgcgt gagagcaaca aaaaaggctt agcaataacc
    31801 acaccgcaga gcctttcaca ctaacactaa aacgaattta acaaagcagg caagctatta
    31861 tcaaagaggt tttagtaaag atttatacct agattatagc atatttaggg caatttgacc
    31921 atacggagag cgccaactct ttaaactggt actttctcat gctctcaatt tggcgactca
    31981 gagcgtgagg ctatgaattg caagaaaaac tgtataagaa acaaccatta aaaaccccca
    32041 cactctcggt cggcaaactt ctgagcgtga ggatatccag tatagtaaaa ggcattaaaa
    32101 gctcttagag caattacaca acatagaaac aaaggtaaaa aacatgacag aaacaacata
    32161 cgagaattta actagacata tagacagaat tagcgcagaa atgcgagaaa ttggcgaaaa
    32221 aaatgggctt agtagacttt cattattggc aaatcagaca aaattcatca aagaaaattt
    32281 acaccgttta ctttggattg aacttcctga attgaatgac agccataaaa tcgaggcagt
    32341 ttctaaaagc actacgggaa tgtttttcca cgctggtatt tttgaaatgg acgctatgcg
    32401 acaagcattc tttaaacgcc aagctatgca cttttttgac aacgaagcag agcaacaggc
    32461 gtatatagaa catgctgaaa aggagtattt agaggctact ataaccttaa aagatattct
    32521 ttttaactct aaaaatggaa ctcagagagt aaataaaagt tgtcttatag agaagtttga
    32581 ggaggcaatg caatgacact aaacctagac aacatgacac aagcagagtt tgatgaagta
    32641 atggctgaaa ttaaggaaaa acgccccaac ctcttccagt ttattgctga ttttgtagat
    32701 cgaaaagtaa gcactgagga ggtagacgaa tacctgaaga tgaaacatga aaaacaagtg
    32761 gaatttatca agaattatca agcgagggca taacatgaat gagttagatt tgaccaatac
    32821 acaatcggta atctttatgg tggtattgat tggcttactg ctttacctaa accaccgaga
    32881 ccgcaaaaaa agcgcccaat ttgagcgaga aaaccaacag aggatagaaa cacctagcga
    32941 ggatttaagc cctgattatg ggcgttatat ccagcttgca ggggtaagag tttacggagg
    33001 aactgaatga gtctatcaga gaatgacaaa cgagtattaa gactaatcaa ggtaggggct
    33061 gagaactcca taacaggggc agaaatcagc cttataacta agctggcgga aagaaccgta
    33121 caagatatta tcagccgtct aatcacgcgt catagtgttc ctattgttgg ggttcgccat
    33181 gggacattta gaggatattt tatcccagct aacaaagagg agctactgga cggagcaaag
    33241 gcattctata accaagtaca ggaagaacag aaacgcctaa ctgtcctttt gaatgctgat
    33301 ttagagagtt acaaagaaac cttgaaggag gtgggcggat atgtttagcc taagccgaga
    33361 aagtgagcaa gacctagcgc atggcattct ggaggtagta gaaagatacc tggaagcgcg
    33421 tgatacagtc aagccgcgac tgacaggttt aatatcagcc caggaagtca tggacgagtt
    33481 agatataaaa tacatgacac tccaaaagtg ggaaaaagca gggctaagac ggtatcagcc
    33541 accgctagaa gatactagga aaatctatta taaaatatct gacatctgga agtttttggg
    33601 ggtggaaaat ggcaaggtat agtattcatc cggcagataa taaagggcat tatcacaata
    33661 ttaaatttta caaagagcgc aggccaaccc tagaccagct aaaggaacag caaaggctta
    33721 aaaagctgaa gaaaaaacgc aaagaggggc gatagtatga caatttatga ggctaaaggc
    33781 tttcagagta atcttgtcta tccatttgat aaaattgagc ctttccagta tattgaacga
    33841 ttcaagccct tagtagttcc tgaaggggca gatattgagg aatacaagcg aactcaagcg
    33901 ccttactgta taagtggcaa agtgacgcca gaaaagcatg gcagttacaa gcgaaacaac
    33961 tccagtctaa tctatcggga tttgattttc cttgattatg acgatataca ggggacgtct
    34021 gagggcttta taaaagccat ttctagcgct ttatttggct actcttacat cttatacccg
    34081 actatcaaac atagcttaga aaagccccgt tttcgccttg tagtgaagcc tgacaacgtg
    34141 atgaatgagg cgacctataa gcaggtagtg aaagagattg ctgacaagat tggactcccc
    34201 tttgatatgg ccagtttaac atggtcacaa ctccaagggc taccagtcac aacaggcgac
    34261 ccagcaagtt atcaaaagat tgtagagcat ggacttgatt atccagtacc acagacaacg
    34321 gctgaaccag tcaaacagaa tgcggcaagc cttccataca ctccaaggcc aagcgggcag
    34381 aaatctatga ccatgaggat cattgacacg cttttcaacg gatttggaga cgagggaggg
    34441 cgcaacgtag cactgacacg atttgtaggc ttactcttta ataagtgggt tgattgtgac
    34501 ctagagacag cctatgaact tacaaagata gccaatagcg tgacagttga accattgccg
    34561 attgaggagc tagaccgcac ttttagcagt atagcacggg ctgaatatag aaagagaggt
    34621 tagaaccata gaactagaag aattagcaaa cctaaaaagt gaaatcttgg aggtaatgga
    34681 gcaagaacac cctcctagaa cgatgaagga gcttgaaaat cgtatcttta aagctggaga
    34741 agaatggcgg gcagaacata ctgaaactaa ggtaaatgag aacacagggg acgttaccga
    34801 aaaggttgcc atgccccaaa ccttcacagt agctaaaata ctgagcgaga ttgtcacatt
    34861 tacttttatc agcaagagca atatacctga ttatagccta ctctatatct atgatttaga
    34921 cgagggtatc tataccgcta gtaatgatct attcaatctt ttgtgtaaga cctttgacgt
    34981 tagaattaaa cccagagagt ggccacagat taagttaatg gttagaacat tggcaaagat
    35041 acgaaaacct ttagaaagtg ctaacctcat tcccgtacag aacggcatta tcaacttaga
    35101 aactaaggaa ctactcccct ttagtcctaa gtatgtaatt acaagtaaga taagcacggc
    35161 ctaccacgcg cctaaacgag tcccaacaga tagagaggga aaaacttttg atgattggtt
    35221 gaactcaatc gcttgtaatg atagtgaact ggtaacactg ttttggcaga ttatccttga
    35281 agctattaac cctaaccata ctcgaaataa gtttgctatc ttctacgggg acggtaacaa
    35341 tggtaaaggg acatttcagc gcttccttat caacctgata ggggaaagca atatatcagc
    35401 cttaaagcct gcacagtttg ctgaaaagca taacttggag accttggtag gtaaggtttg
    35461 taatattggg gatgaagcac ctaacgaata cttaaaaaat ccgtctgatt taatgagtat
    35521 cactagtggc gacactgttc tagtcaatcc aaaaggacgc ccagcctttg aagctacttt
    35581 caagttattc aatatctttt cagggaatta tatccccaat ggtggcaaca agacaaaagg
    35641 ctggtatcgt agaattatga ttgtcccttt taatgctgac tttaacgggg agaaggaaaa
    35701 accttggata aaaaatgagt ttttagcaaa caaggaagtc ctagaatatg ccctctacaa
    35761 agctatcaat caagagccat ttactcactt tatcgaacct aaagcagtta aaggactcct
    35821 agaagaatac caggaagata atgactactt actttcatgg gttaagcatg aatacatgga
    35881 aaaaggttgg catgagctgg acgtagtacc tgtttttatc gttacaagat cactaaagca
    35941 ctatgccgaa gatatgggaa tacccaagcc caatgtttac ggggctggta aagaaactat
    36001 caagcactta caacagttga cacctaatcg gtattctcta agaaagaaaa gagtttctcc
    36061 agaagatttt gaaaaactag aggcatggga cgttgacaag ataaaaatgc ggacacctca
    36121 acactctatc actaaacaag aataagtgtg acgttctttt tttgcttaaa cccttgataa
    36181 tactgatttt cttgaaaaaa gtgtgacgtt gtgtgacgtt ctcaaaaaag aaggtcacac
    36241 cccttgaagc cttgatatat ctaactttag gggaataggt gtgacgttgt gacattcttt
    36301 ccaactctta tatatagaga aaaatacagt atttatatat ataggaacga taaaacaaaa
    36361 gaacgtcaca gggtcacagg ggtggtgaaa cacctagagc ctcaagggtt tgaacgtgtg
    36421 acgttctttg tcacaaaagg tcacagaagg tcacagaaaa cgaaaaatat tacataattt
    36481 accttaaaac aaagaaatga caacaacatg aaagttaaac tatttgaata tactagacga
    36541 tgggaaaaag aagactttga gaaagagatc gatgacttca tggcaactgt tgaagtgctg
    36601 gacgttaaat tttctggtac accatctagt gaatccttta attcggtggc taccgtattg
    36661 gtattataca gataacaaaa tggggtagat agtaccgacc cccttgcaat ggtgtaacta
    36721 ctagtgacac ccttaaaaac agaaagagga aaaacaacat gacattaaaa acattttcat
    36781 ctaaagccaa aacatttact ttcacttacg aatttaaaga cctagataca gctctggtag
    36841 caggtcacgc gttactggga tatatgactg gaacatattg ccagcctgta atctcattga
    36901 cctacaagga taaaggcacg ctagtagctg agtatgtgga agatcacaag ctaaacaaga
    36961 cctttaagcg tatttgtgac agttttaaag actaccacaa acaaccagga gaggctgaag
    37021 catttgaaga acgttacaaa cgggagcgcg tgctccaact caaagagtca gaggactttg
    37081 agagtttact gaataaggtc acagactacg agctggaact attagactat gctgaccgcc
    37141 tgctttctga taagcctatc cctatggact ctatgactgc ttttgctacg ttggaaatgc
    37201 tgggcgatga aagtattagc ctactccaaa agttggacgt agagggcgaa tataaaggcc
    37261 ttgctggtta tacagagcat ttgaagtaga atacagggga gcaatcccct ttttgctatc
    37321 aagtcaatag ttttgggttt ttccatatag ggggaaataa tgaagcagtt agcaatagaa
    37381 gcaatcacta aaccaatgaa gctgagagga atatctaagg gtatagccga gttggatggt
    37441 caacgtttag agattgattt ggatagttta atgattgatt ttggtggaga gtcatttgaa
    37501 ttagacagaa tagcaggaac taagggaggt aatcgatatt tttttctttg ccctgattgt
    37561 ggtagacggt gcaggttgct ttataaacgg tatttgtatt ttagttgcgg tacttgtcta
    37621 gatatccaca agcacaccct gaaccgcagt aaaacggatt gccaatacta ctgggagctt
    37681 gcactaaaag aagctagaaa ggtagaacca gggtggagtc ctagacgtgg cggatatatg
    37741 tttgatagtt ttcctgaaag accaaaatac atgaaacaga aacgatatta caagcattat
    37801 caaaagttta ttaactacac cagaaaaggg gatagctttt ggctgaatgg tttgagttct
    37861 ctaaggtaat ttgtagtagt gtgcaattta caaaacaaac aaatactaca tattagacgg
    37921 tttgaatgtt aaaaaagcta gatatatcaa ggatttaatt aagtatagcg ttccaaaaaa
    37981 agggtgcagt aagcgttcca aaaaagggtg aggtaagggt gaggttgaat atttaaaaaa
    38041 ggctaagatt aggctaaggt cacatacttc aaaatagcaa ggttttagca aggtacaggg
    38101 cttttttcta gtgatagaac cccaaggtta ccacaaggta tagctacttt tttagaacca
    38161 tagaacggta aggttacggt aaggtatcga agttttccaa tggtaaggtt ttggtaaggt
    38221 agcatatata aaaagtacaa ggttagtaca aggttacata cttaaaaata ctaaggtttt
    38281 acaaaggtag agaggtttac cgagggttag aaaaggtgag attttgctta ggtagtggca
    38341 gtaaatatgc ctgacaaatg gcagggttat gtgtgttgaa ctccgagcga acgccgagaa
    38401 agtggctata tcccccctat catttatcaa gtagataaga gcaataaaaa ccctccttaa
    38461 ccccctgaga aacgacaagc agataagaga agtttttagc cctcttattt cggatctact
    38521 ccttgcagaa tgacaagcag ataaggacga caataagcct tcttaactgc ttacaaaacg
    38581 atagggagtt aagacgaatt taaaagcccc ttattttcgt ttttctcctt gtcaaacggg
    38641 aaggaaataa gacaggaaat aacatcgctt attttgattt tgctccctga aaaactgtaa
    38701 ggagataagg agacttatta gcttccttaa tttgaatttt ctccttacaa aatgacaggg
    38761 aaataagaac taaaataact ccccttattt tcctaccaaa tgataaggag ataagagcag
    38821 tttaaaagtc tgttattttg gatttgttgc ttacaaaatg ataagcagat aagcaaagaa
    38881 ataacttgcc ttaattgctt gcagaatgac aaggaaataa gagagataaa aacatccctt
    38941 aattgcttat caaatggtat ggagaatgga cttgaaccta gagcgaagct agagaaaatg
    39001 aaaaaaagcc agcacagggc tgactccttt atgaattatt ccataaaact attatatcac
    39061 aaaggaggcc gaggcatgac accagagcaa gtaaaagaaa aactagaggg cgttaagtgg
    39121 ataaacaagg agatcaaagg cttatatttg gaattggaaa ccctggaagg tggcattatc
    39181 aaaaaaccaa cactaagcca tagcagggtg cagacaagta gagagaataa gacagagaac
    39241 aatcttataa gtgttctgaa gctaaaagag gacactttac agagaattga gcgacttact
    39301 gaagagagaa tgaaaatatc tgagctaatc gataaactgg ccaatccgct tgagcgttct
    39361 gttctaagac ttttttactt gaatgatctt gtagtttcgg aggtggctga agaaatagat
    39421 agatcaaata ctacagtata cattataagg caaaaagcta tagaacactt aacaggtatt
    39481 gtaaacgggg attgatttaa ccttaccacg gaattaggag agtatggggg agtcctaagc
    39541 cacatattcg cccgtatttc gctttgtttc gtactggaca actaaaacac catggataaa
    39601 ctacaaaccc tcagaaacga atctgggggc ttttgtgagg tcataatctt ataaaccacg
    39661 cgcttcatgg tataatatat ctatcagcaa ccagcaataa aaaagcacgt ttgaccgtgc
    39721 tagtttcttg cctgctgaac tcgtcaaatc ttagcccttt tgtggggctt ttttgctccc
    39781 ctttttgcgt actttggggg agcaagtagt aaaaagtaat gttagtaatt tttattaaaa
    39841 agcgcgtgat ataagggtta ggaagcccta aggaaacata aaataagcga ttgttgatta
    39901 tactacaaaa tcggcctttt gggtaataga atctcacttt ttttggtata atggtaagca
    39961 ataatggact agaaagaaca aagatgcaag ataaaattgt cattcatggg gcgcgtgccc
    40021 ataatttaaa aaatattgat gtggagattc cgcgagacaa gttggttgtc gtgactggct
    40081 tgtcaggttc agggaagtcc agtctggctt ttgatactct ctatgcggag ggacaacgtc
    40141 gctatgtaga gagtttgtct gcctacgctc gtcagttctt gggaaatatg gaaaaaccag
    40201 atgtagatgc cattgatggt ctcagcccag ctatttccat cgaccagaaa acgactagta
    40261 aaaatcctcg ctcgacggtg ggaacgacga ctgaaatcaa tgactatctg cgtctcctct
    40321 acgcacgtgt ggggacgcct tactgtatca acggacatgg agctatcaat gcttcttctg
    40381 tggagcaaat cgttgataag gttttggagt tacctgaacg ccagcgcttg cagatcttgg
    40441 ctcctgtcat ccgcaagaaa aaaggccaac ataagagtgt tatcgagaag gttcagaaag
    40501 acgggtatgt tcgtgttcgt gtggatgggg aagtctatga tgtgaccgaa gtgccagagt
    40561 tgtctaagag caagcaacac aatatcgatg tcgtggttga ccgtattgtt atcaaggagg
    40621 gcattcgtag ccgtctcttt gattccattg aagctgccct tcgtatcgca gaaggttatg
    40681 tgattatcga caccatggac gactctgagt tgttgttctc tgagcattat gcctgtccag
    40741 tttgtggatt tactgtccca gagttagaac ctcgtctctt ctctttcaat gctccctttg
    40801 gctcttgtag tgagtgtgac ggcttgggga ttaagctgga ggtggatact gatttggtag
    40861 tgccagatgc cagcaaaacc ttacatgagg gagcgctggc accttggaat cctatctcat
    40921 ccaactacta tccaaacatg ttagagcagg ccatgaaagt ctttggagtg gctatggata
    40981 agccttttga ggacctgtca gaagaagata agaacttgat tctctatggg tcagatggta
    41041 aggaattcca tttccactat gagaatgaat ttggtggcgt gcgcgatatc gacattccgt
    41101 ttgagggagt tatcaataat atcaaacgtc gttaccatga aaccaatagc gattacactc
    41161 gcactcagat gcgtctctac atgaatgagc tgacctgcgg aacctgtcaa ggctatcgtc
    41221 tcaatgacca ggccttgtct gtccgtgtgg gcggccagca agggccacat attggagaaa
    41281 tctcagacct gtctatcgct gaccacttgg acttggtgag ccagttaact ttgtctgaaa
    41341 atgaagccat cattgctcgt cccattctca aggaaatcaa ggatcgtttg accttcctta
    41401 ataatgtggg tcttaactat ctaaccctgt cacgttcagc aggaaccctt tcaggtgggg
    41461 aaagtcagcg cattcgtttg gcaacccaga ttggttccaa cctatcaggc gtcctctata
    41521 tcctagacga gccgtcaatc ggtcttcacc agagggacaa tgaccgcctg attgccagtc
    41581 tgaaaaagat gcgtgacttg ggcaatactc ttatcgtggt ggaacacgac gaagatacca
    41641 tgcgtgaagc tgattatctg attgacgttg gtcctggtgc cggtgttttt ggtggtgaga
    41701 ttgttgcagc aggtacacct aagcaagtgg ctcgcaacag caagtctatc acaggtcagt
    41761 acttgtcagg caaacgtgtc atcccagtac cagaagagcg ccgtgtcgga aatggtcgtt
    41821 ttattgaagt gataggagcg cgtgagaaca acttgcaaaa tgtcacggct cgctttccac
    41881 taggaaaatt tatcgcagtg acaggtgtgt cgggttcagg gaaatcgact ctaatcaaca
    41941 gcattctcaa aaaagccatt gcccagaagc tcaaccgtaa ttcagacaaa cctggtaagt
    42001 ttaagactat tacagggatt gagcatgtcg accgtttgat tgatattgac cagagcccta
    42061 tcggacggac gccgaggtct aacccagcta cctatacagg agtttttgac gatatacgtg
    42121 acctttttgc tcagacaaat gaagccaaga ttcgaggcta caagaagggg cgcttcagtt
    42181 tcaacgtcaa gggaggtcgc tgtgaagctt gctcaggtga cgggattatc aagattgaga
    42241 tgcacttctt gccagatgtt tatgtggctt gtgaagtttg ccacggaacc cgctataaca
    42301 gtgaaaccct agaagttcac tacaaggaaa agaatatttc gcaggtcttg gatatgacgg
    42361 tcaacgatgc ggtagaattt ttccaacaca ttccgaaaat tcaacgcaaa ctccagacca
    42421 tcaaggatgt aggtctaggc tatgtgacct tgggacagcc agctaccacc ctttctgggg
    42481 gagaagccca acgtatgaag ttagctagcg aactccacaa acgctcgaca ggaaaatctt
    42541 tctacattct ggatgagccg acgacagggc ttcatacaga ggacattgct cgcctgctca
    42601 aggttttagc tcgctttgta gacgacggca atacagtcct cgtcatcgag cacaatctgg
    42661 atgttatcaa gacggcagac catatcattg acttgggacc tgagggcggt gtcggtggtg
    42721 gaaccatcat cgtaacagga actccagaag aagtagctgc caacgaagcc agctatacag
    42781 gacactattt gaaaggaaag ttacatcatg aataaacgcg tacaagcatt tctagctaaa
    42841 atgcaagaaa aagaactaga tggtatcatc atcaacaatc ttaaaaacgt ctattatttg
    42901 actggttttt ggggctcaaa cggaacagtc tttatcagcc gtgaccgtca ggtcttagtg
    42961 acagactctc gctatatcat cgcagctaag caagaaacca gtggttttga gattgtggct
    43021 gatcgtgatg aattggctgt cattgcagga attgttaagg acatgggctt gactcgtatc
    43081 ggttttgaag atgagatttc agtgtcttat taccaccgta tgcaggcagc ttttgcaggt
    43141 ttgaacttgc ttccacaaac tcagtttgtg gaaggtcttc gtatgattaa ggatgaggca
    43201 gagattgcag cgattcgcaa ggcttgttct atctcagacc aagctttccg cgatgcgctt
    43261 gactttatca aaccaggaaa aactgaaatt gagattgcca acttccttga cttccgcatg
    43321 cgtgagttgg gagcatctgg cttatctttt gatacgatcc tagctagcgg tatcaattct
    43381 tctaaacccc atgcccatcc aatgcacaaa ccagtggagt tgggagaagc cattaccatg
    43441 gacttcggct gtctctatga ccactatgtc agtgatatga cccggactat ctatctaggg
    43501 catgttagcg atgagcaggc agagatttac aatacggttc taaaagctaa ccaagccttg
    43561 attgaccaag ctaaggcagg cttaggtttc cgtgactttg acaaaatccc tcgtgatatt
    43621 atcattgagg caggttatgg cgactacttt actcacggca ttggccacgg tattggtctg
    43681 gatatccatg aggaacccta ctttagccag acttctacag aaactattaa gacaggtatg
    43741 gccttgaccg atgaaccagg tatctatatc gaaggcaaat atggcgttcg tatcgaggat
    43801 gatatcctga ttacagagac aggttgtgaa ttattgaccc tagctccaaa agagttgata
    43861 gtcatttagt tgtttgtcaa gaaaaaagta cgaaaatgac gaaaaaagtc aaaaaaaatt
    43921 aaaaataggt cgcaagtcgg atgtttttta tggtataata gactaaactg atagtaacat
    43981 gtagcgaaag gggtaggtac atgattaaaa tttatacagt ctcaagttgt actagctgta
    44041 aaaaagcaaa aacctggctc aatgcccacc agttaagtta taaagaacaa aaccttggta
    44101 aagaaggaat tacgagagaa gaattactgg atattctaac caaaacagat aacggaatag
    44161 ccagcatcgt ttcatctaaa aatcgctatg ccaaagccct tggagtggat attgaagatt
    44221 tgagtgtcaa tgaagttctc aatctgatta tggaaacacc gagaatttta aagagcccaa
    44281 tccttgtaga tgaaaaacgc ctgcaagttg gctacaagga agacgatatt cgtgccttcc
    44341 taccacgctc tgtccgtaat gtagaaaatg cagaagcacg tttgcgtgca gctctataaa
    44401 catcaaggct gggagcactt cccagtctta ttctatttta atttcaaaaa gaaagaagaa
    44461 agaaatgaaa aaaatagttc ttgttagtct agctttcctt tttgtcctgg ttggttgcgg
    44521 acagaaaaaa gaaactggac cagctacaaa aacagaaaaa gatacgcttc agtcggcatt
    44581 gccagttatt gaaaatgctg agaagaatac agttgtaact aagactttgg tcttgcccaa
    44641 gtcagatgat ggtagccagc agacacaaac aattacttat aaagacaaga cttttttgag
    44701 tctaactatc caacaaaaac gtccagtctc tgatgagttg aagacttata ttgaccaaca
    44761 tggagtggag gaaactcaaa aagctcttct tgaagcggag gagaaggata agtctatcat
    44821 tgaagctcgt aaattggcag gtttcaaact tgaaacaaaa ctattgagcg caacggaact
    44881 tcaaacaacg actagttttg attttcaagt tctggatgtc aagaaggctt cccagttgga
    44941 acatctgaag aatattggtt tggaaaatct tttgaaaaat gaaccaagca aatatatttc
    45001 agatagattg gcaaatggcg cgacagaaca atagaaaatc caaataaata gactgcctga
    45061 attgtagaag gtaaggaatt atgctataat ggtactattc taaggaaaga gggtgttaga
    45121 atgggattta ctgaagaaac agtacgtttt aaattggacg attccaataa aaaagaaatt
    45181 agcgaaactt tgacagatgt ttatgcttcg ttgaacgata agggttacaa cccaattaac
    45241 caaatcgtag gttacgtatt gagtggagac cctgcctacg ttcctcgtta taataatgca
    45301 cgaaatcaaa tccgtaagta tgagcgtgat gaaatcgttg aggaattggt tcgctactac
    45361 ctcaaaggac aaggagtcga tctataacct atgagaatta tgggattgga cgtcggttca
    45421 aaaacggtag gggtggcgat tagcgatccg cttggtttta cagctcaagg gcttgaaatc
    45481 atccagataa atgaagaaca aggccaattt ggttttgacc gcgttaagga attggttgat
    45541 acttacaagg tggaacgatt tgtagtgggc ttgcctaaaa acatgaacaa tacaagtgga
    45601 ccgcgcgtag aagctagtca agcctacgga gcaaagctag aagagttttt tggtttacca
    45661 gtagactatc aggatgaacg cttgacaaca gtggctgctg agcgcatgtt gattgaacaa
    45721 gcagatatca gtcgcaataa gcgcaagaaa gtcattgata agttagcagc tcagctgatt
    45781 ttacaaaatt atttagatag aaaattttaa tataaaggag aggctatgtc acacgatcat
    45841 aaccacgacc acgaagaacg tgaactaatc acactagtag atgagcaagg aaatgaaacc
    45901 ttgtttgaaa tccttttgac aattgatgga aaagaagaat ttggtaaaaa ctatgttctt
    45961 ctagtaccag ttaacgcaga agaagacgaa gacggacaag ttgaaatcca agcttactca
    46021 ttcatcgaaa acgaagatgg aacagaaggc gaattgcaac caatcccaga agactcagaa
    46081 gacgaatgga acatgattga agaagtcttc aacagcttta tggaggagtg atacagtctg
    46141 ggagactgta tcagcccaac tcccagaaat ggggaagagt tggaacgtcc agtgaacatt
    46201 tttaccccaa ctcttagaaa ttgagaagag ttggaacatc tagtggatgt ttttagccca
    46261 tattcacatt catagtggct agttattagc taaccaggta agaggtcggg acgaaaatcc
    46321 tggccttgtt tttattagta accatacttt aatgcgataa ttgattggac ttttgtcaag
    46381 gagatgtgta tgtttgaagt agaagaatgg ctccatagtc ggattggttt aaattttcga
    46441 tcaggtttgg gccgaatgca gcaagcggtg gatttgttag gaaatcctga gcagtcttac
    46501 cctattatcc acgtaacagg gactaatggg aaaggatcta ccattgcttt tatgagggaa
    46561 ttatttatgg ggcatggcaa aaaagttgcg acctttacct cccctcatat cgtatccatc
    46621 aatgaccgaa tttgcattaa tgggcaacct atagcagacg cagactttat ccgtttggct
    46681 gatcaggtca aggagatgga gaaaacgctt ctgcaaactc ctgaccagtt gtcctttttt
    46741 gaattgctga ccttggttgc ttttctttat tttagggagc aagaggtgga tttggtttta
    46801 ttagaagtgg gaattggtgg cttacttgac acgaccaatg tggtaactgg agagcttgct
    46861 gtcatcacct ccattgggct tgaccatcaa gaaaccttgg gtgatagtct agaagcaatt
    46921 gcagagcaga aagctggtat tttcaaggct ggtaagaagg cagtgattgc gaaattgcct
    46981 ccagaagcta ggcttatctg tcagaaaaaa gccgaatctt tagctgttga cctttatcag
    47041 gcaggtcaag atttttcagt gctgaatggt gatttttcaa gctctttact aaatctttca
    47101 cagctgaaca taggcttaga aggagcctat cagcaggaga atgcggcctt ggcgttgcaa
    47161 acttttcttc tttttatggg agaaagaaag gaagctattg atgaacaggc tgtaagaaag
    47221 accttggaac aaacccattg ggctggtcgc ttggagcgta ttcgcccaca gatttacttg
    47281 gatggtgctc ataacctccc tgccttgact cgcttggttg agtttatcaa agaaaaagag
    47341 caggaaggct atcgacctca aatcctcttt ggatccttga aacgtaagga ttatcaaggg
    47401 atgttgggtt atctgactga aaatttacct caagtggaac tcaaaatgac cggctttgac
    47461 tatcaagggt ctttggacga gacagatgta acaggttacc atgtaattcc ctcttaccga
    47521 gaatttatca gcagtttcga agaaagggca gacgctcaag acttgctgtt cgttacaggg
    47581 tctctctatt ttatctcaga agtacggggc tacctgctgg accgtgagca gataaattga
    47641 cccccttttt tgaacttgtt atactagggg aattgctggt tagagaaaat ttctctaaat
    47701 tggtagcaga aaggaaattc atcatgaaat taaaaagatt cacactttct cttgcttctc
    47761 tagcaagttt tagtctctta gtagcttgtt cacaaagagc tcaacaggtt caacagcctg
    47821 ttgctcagca ggtccaacag cctgctcaac agaataccaa tactgcaaat gcaggaggta
    47881 accaaaatca agcggctcca gtacaaaacc aacctgttgc tcaaccgacc gatattgatg
    47941 ggacttatac tggtcaggat gacggagacc gtatcacttt agtggtaact ggaacgactg
    48001 gtacatggac tgagctcgaa tctgacgggg atcagaaagt caaacaggtt acatttgatt
    48061 cagcaaatca acgcatgatt attggcgatg atgtcaaaat ttacactgta aacggtaatc
    48121 aaatcgtcgt agatgatatg gatagagacc catcggacca aatcgtttta actaaataag
    48181 actatgcaag tagaaagggc tggatttttc agccttttta cttttaccta gaaaataatc
    48241 ataaatactt gccttctacc gaatacctgc gttatactag tatcaattac ttgtttttag
    48301 cattcaaact atcaaggagg ggatatgaaa tataggaaat ttcaattatt gatgtccaag
    48361 tatggcttta gtctttcgat tatgctactt gaactttgtc ttgtttttgg tctctttctt
    48421 tatttaggac gcatggctcc cattttatgg attactgtcc tcattctact gagtatcatc
    48481 acaatcattt cgatagtcaa ccgtaatacg actcctgaga ataaggtaac ctggttgtta
    48541 gtagcctttg tgccagtatt tggtcccttg ctctatctga tgtttggtga aaggcgattg
    48601 tccaaaaaag aaatcaaaca actgaagaag ctaggctcta tgcatttcca agaagcaaat
    48661 agccagctac taaaagagaa attaaaagaa agtgacaagg cagcttatgg agtcatcaag
    48721 tccttattga gtatggatac caatgctgac atctatgatc aaactgcctc tacatttttt
    48781 cctaacggag aagctatgtg gaaaaagatg gtagaagatc ttaaaaaggc tgagaaattt
    48841 attttcttgg aatattacat tatagaagaa ggtttgatgt ggaatcgcat actagatata
    48901 ctagagcaaa aggtagctca gggtgtagag gttaagatgc tctatgatga tatcggctgt
    48961 atggctactt taacaggaga ttatgcacat cgacttcgtc agctgggcat cgaggcccat
    49021 aaattcaata aagttattcc tcgtttgaca gtggcttata ataacagaga tcatagaaaa
    49081 atattgattg ttgatggtca gatagcctat actggtgggg tcaatctggc agatgagtac
    49141 attaaccacg tcgagagatt tggttattgg aaggatagtg gaattcgctt agacggacta
    49201 gcagtaaaag ccctgacacg cttatttttg accacttggt acattaatcg aggagaaatt
    49261 agtgattttg atcaatatca tttagaaaat cattctatcc cgagtgacgg tttaaccatt
    49321 ccatacggaa gtggacccaa gccaattttt cgagcgcagg tagggaaaaa agtttatcag
    49381 agtttaatca atcaagcaac ggaatcggtc tatattacga caccttattt gattatagat
    49441 tatgatttaa cagagacaat caaaaatgca gctatgagag gggtcgatgt tcgaattatc
    49501 accccttaca taccagataa gaagttcatt cagttagtca cgagaggagc ttatcccgac
    49561 cttctttctg ctggtgttcg gatttatgag tatagtccag gttttattca tagtaagcag
    49621 atgttggtag acgaagattt tgcggtggtg gggacaatca atctcgacta ccggagcttg
    49681 gtacaccatt atgaaaatgc agtcttactc tataaaactc cttctataag ggaaatcgcc
    49741 cgagattttc gaaatatatt tgcagattct caggaagtct atcctcattc tatcaaaacg
    49801 agctggtatc aaaagcttgt aaaagaaatc gcccagctat tcgcccctat cttataagaa
    49861 atctagaact taggatacaa accagaccta tttttcttgt cttttacgaa tagaaagaaa
    49921 gaggagggga attcatgcta actaaggaag aagtgaatga tatgattgag ttcaaacaga
    49981 cacatttaca ccgctttcgg gaaattgaaa cctttgtgaa actatgcaaa aaatcactca
    50041 aacagccatc gcaagctgac aatcctagga ctttttgata tactaagaca gataaattga
    50101 acaggagaaa cgatatgagt gtgtatggta gagtagaaga agttcataag gagaatcgtg
    50161 aacctctaga ataccaaatc gaacaagaat cgcatcatcg tgaatcaagt cgtcttcctt
    50221 tagtgaaaat tttactatgg agtacgcttg taacggggat aactctagga gtaccgctat
    50281 tactcgactt aatgagtgca caagaagtgc aggattttta tgcaggttgg gcgcttcatc
    50341 agacagggaa gatttacagc gactattatg gaagtcaagg tttgctttat tatttgctga
    50401 cttacgtgag tcagggcgga tttttctttg ccatctttga gtggttagcc ttggtagcag
    50461 gcggattttt cctttttaga tcagcggaca ccttgacaga gcaaggagac caagctggac
    50521 atctggtgac tattttttac atgctagtta caggtcttgc ttttggtgga ggctatgcga
    50581 ctcttttagc gcttcctttc ttattcgcag cctttagttt agttgcggct tacctaagca
    50641 atccaagcca tgataaggga tttgtacgga ttgggctagc tttggcaggc ggatttttct
    50701 ttgctccctt atcatcgctc ctgtttattg ctgtagtgag tttaggcttg ttggtcttta
    50761 accttgggca tagacgcttt gcgcatgggt tttatcagtt tcttgcagtg gctttaggtt
    50821 tttcacttgt cttttatcca actgcctact atagtgctgc aacaggaagt tttggggatg
    50881 cgattagtgg tattcgttat cctattgaca gtattcgctt tgattttact tctaaaattt
    50941 tagagaatat gtttttttat ggcttgttgt cccttggttt gggatttgtg gtttgtatct
    51001 ttttaggtct ctttcaatcc aaacccttta aactatacgt catttcggtt cctgcaagtc
    51061 ttgtggtaat tttaggtttg attttacttt tcttttcaca agagcctctg cacgcttctt
    51121 atttgatggt cgtcttccct gttttcctac ttttattggt aaccaatatt aagagtcaac
    51181 agagggggcg tagtgctaga agaagccgaa gagaaacgcc agttagccta tggagtcgtt
    51241 tcttcaaagg aaatctatat ctgctagttt ttgggtttgt ctatcttttg tctgttcctt
    51301 ttttgatgaa gtttgtcctt tatccagtac cttatcaaga acgtaatcgt cttgctgatt
    51361 tggtaaaaga ggagacaaat acggaagatg ctatctatgc atgggatgat actgcgactc
    51421 tttatcgtaa gagtgagcgc ttgtcgccat cggcgatttt gtccccgttg cactatacag
    51481 caactgagga aaatcgtaat aagttactta atgacttgaa agaaaaacaa cctaaggtga
    51541 ttgtggtaaa tgataaggtg gtagtctggt ctgaagtgga aacactctta aaagaaaatt
    51601 accaacaagt aaagactgat tactcagagt ttaaagtcta taaaattaaa taa
//
LOCUS       DAVLMQ010000008        49841 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000008 DAVLMQ010000000
VERSION     DAVLMQ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.008"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            512..808
                     /locus_tag="VXF95_000611"
     CDS             512..808
                     /locus_tag="VXF95_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000911560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1081198.1"
                     /translation="MLKFRKVVASSLAVLAFSLALPVLAVSHRGGEWTYGGHHDPYNW
                     GAFSNYYHGSQYHWAYVGSNERDNQKTVYAGAHSAAYAFVNTNLGERITFDAGW"
     gene            911..2926
                     /locus_tag="VXF95_000612"
     CDS             911..2926
                     /locus_tag="VXF95_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1081199.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSHYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDPNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMHLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFGALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLTI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNFITSTEWHDY
                     SPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLDVGEFVLLLPEHLRSEEDHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAVLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            2928..3560
                     /locus_tag="VXF95_000613"
     CDS             2928..3560
                     /locus_tag="VXF95_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081200.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLAYLDLDKRIFELSGGESQRVALAKIILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDHLK"
     gene            3701..3979
                     /locus_tag="VXF95_000614"
     CDS             3701..3979
                     /locus_tag="VXF95_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HEV1081201.1"
                     /translation="MKKFDNYIIEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(4489..4902)
                     /gene="ndk"
                     /locus_tag="VXF95_000615"
     CDS             complement(4489..4902)
                     /gene="ndk"
                     /locus_tag="VXF95_000615"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HEV1081202.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYLPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(5013..8690)
                     /gene="rpoC"
                     /locus_tag="VXF95_000616"
     CDS             complement(5013..8690)
                     /gene="rpoC"
                     /locus_tag="VXF95_000616"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HEV1081203.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPHAVNEEEYLNPTVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            complement(8723..12334)
                     /gene="rpoB"
                     /locus_tag="VXF95_000617"
     CDS             complement(8723..12334)
                     /gene="rpoB"
                     /locus_tag="VXF95_000617"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1081204.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            12750..12820
                     /locus_tag="VXF95_000618"
     tRNA            12750..12820
                     /locus_tag="VXF95_000618"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12782..12784,aa:Cys,seq:gca)
     gene            complement(13018..14349)
                     /locus_tag="VXF95_000619"
     CDS             complement(13018..14349)
                     /locus_tag="VXF95_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HEV1081205.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPVIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVYQIGEDTYIVQGTMTLNDFNNYFNVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELISQNKQFILTNDKVKNGRVTKVKIQITEVEIEEETE"
     gene            complement(14640..15464)
                     /gene="endA"
                     /locus_tag="VXF95_000620"
     CDS             complement(14640..15464)
                     /gene="endA"
                     /locus_tag="VXF95_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HEV1081206.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     APEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSNATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            complement(15503..15691)
                     /locus_tag="VXF95_000621"
     CDS             complement(15503..15691)
                     /locus_tag="VXF95_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HEV1081207.1"
                     /translation="MNKKSSYVVKRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            complement(15684..16967)
                     /gene="murA"
                     /locus_tag="VXF95_000622"
     CDS             complement(15684..16967)
                     /gene="murA"
                     /locus_tag="VXF95_000622"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1081208.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            complement(16991..17221)
                     /locus_tag="VXF95_000623"
     CDS             complement(16991..17221)
                     /locus_tag="VXF95_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HEV1081209.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTAENTRKVRV
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            complement(17279..18316)
                     /locus_tag="VXF95_000624"
     CDS             complement(17279..18316)
                     /locus_tag="VXF95_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HEV1081210.1"
                     /translation="MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLK
                     VNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQ
                     FYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
                     DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVIS
                     NVPISFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGID
                     KKVVASARAGAAIFFAPDNPVSEEEQKAHPDAKNNYQTALEAAKTIKTDMKIVPVKTL
                     QDAIDYLKNNP"
     gene            complement(18300..18788)
                     /gene="coaD"
                     /locus_tag="VXF95_000625"
     CDS             complement(18300..18788)
                     /gene="coaD"
                     /locus_tag="VXF95_000625"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HEV1081211.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDKLVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KD"
     gene            complement(18778..19317)
                     /gene="rsmD"
                     /locus_tag="VXF95_000626"
     CDS             complement(18778..19317)
                     /gene="rsmD"
                     /locus_tag="VXF95_000626"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HEV1081212.1"
                     /translation="MKIISGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAERELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            complement(19382..20374)
                     /locus_tag="VXF95_000627"
     CDS             complement(19382..20374)
                     /locus_tag="VXF95_000627"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HEV1081213.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            complement(20487..21170)
                     /locus_tag="VXF95_000628"
     CDS             complement(20487..21170)
                     /locus_tag="VXF95_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HEV1081214.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            complement(21226..21966)
                     /locus_tag="VXF95_000629"
     CDS             complement(21226..21966)
                     /locus_tag="VXF95_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HEV1081215.1"
                     /translation="MTIITSKANSVVKNAKKLHQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLAAFPQTVWISEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSQALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            22000..22278
                     /locus_tag="VXF95_000630"
     CDS             22000..22278
                     /locus_tag="VXF95_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HEV1081216.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            22356..23282
                     /gene="yidC"
                     /locus_tag="VXF95_000631"
     CDS             22356..23282
                     /gene="yidC"
                     /locus_tag="VXF95_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1081217.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPLLLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFST
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(23357..24151)
                     /gene="pflA"
                     /locus_tag="VXF95_000632"
     CDS             complement(23357..24151)
                     /gene="pflA"
                     /locus_tag="VXF95_000632"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HEV1081218.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKQLMDTESYQDYMKRVHG"
     gene            complement(24277..25527)
                     /locus_tag="VXF95_000633"
     CDS             complement(24277..25527)
                     /locus_tag="VXF95_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HEV1081219.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGLHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            complement(25594..26421)
                     /gene="purR"
                     /locus_tag="VXF95_000634"
     CDS             complement(25594..26421)
                     /gene="purR"
                     /locus_tag="VXF95_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HEV1081220.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            complement(26688..27629)
                     /locus_tag="VXF95_000635"
     CDS             complement(26688..27629)
                     /locus_tag="VXF95_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HEV1081221.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMSNKIFAMDNRSFYKPDLD"
     gene            complement(27619..28875)
                     /locus_tag="VXF95_000636"
     CDS             complement(27619..28875)
                     /locus_tag="VXF95_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HEV1081222.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYEVGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGVLFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            complement(28877..29539)
                     /locus_tag="VXF95_000637"
     CDS             complement(28877..29539)
                     /locus_tag="VXF95_000637"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HEV1081223.1"
                     /translation="MSEYKLSENNWTRVAVFAGGNRGHYRTDFDAFVGVDRGSLWVLE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQHFVQARPEKDDTDLELALLTIFEQNPQAEV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMRQIEIEDGQNLIAYCSEGTSQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            complement(29502..30158)
                     /locus_tag="VXF95_000638"
     CDS             complement(29502..30158)
                     /locus_tag="VXF95_000638"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1081224.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDSHFVP
                     QISFGAGVVESLRPHSKMVFDCHLMVSNPEHHLEDFARAGADIISIHVEATPHIHGAL
                     QKIRLLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALREEKGLNFEIEVDGGIDDQTIAQAKEAGATVFVAGSYVFKGEVNERVQTLRKQLD
                     "
     gene            complement(30169..31047)
                     /gene="rsgA"
                     /locus_tag="VXF95_000639"
     CDS             complement(30169..31047)
                     /gene="rsgA"
                     /locus_tag="VXF95_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HEV1081225.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDRGELDFYRQTYGDIGYDFVTSKEELLSLLTGKVTVFMGQTGV
                     GKSTLLNKLVPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     RAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGVIATFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            complement(31049..31921)
                     /gene="rsmA"
                     /locus_tag="VXF95_000640"
     CDS             complement(31049..31921)
                     /gene="rsmA"
                     /locus_tag="VXF95_000640"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HEV1081226.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAQVMAFEIDHRLVPILVDTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPNLPIKVVANLPYYITTPILMHLIESGIPFCEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPEPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLA
                     EFAGLADALKGQGL"
     gene            complement(32052..32360)
                     /locus_tag="VXF95_000641"
     CDS             complement(32052..32360)
                     /locus_tag="VXF95_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081227.1"
                     /translation="MCEKIRIRRVSDYPSARGGLEDILIMENMTNHLLLVQIRVHGYL
                     LDFASIEGQRQKHYRLKNLPQTVELTVDDVEEDVDLTLPENRSYQEADFFERMFRENC
                     "
     gene            complement(32353..32994)
                     /locus_tag="VXF95_000642"
     CDS             complement(32353..32994)
                     /locus_tag="VXF95_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081228.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(32996..35026)
                     /locus_tag="VXF95_000643"
     CDS             complement(32996..35026)
                     /locus_tag="VXF95_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1081229.1"
                     /translation="MKRLFILISMVLVSLYMVITSVDHREEILFGNYPSVDVTGMMTN
                     QPVASREEVTEALSHLAVEHNSLIARRIVEPNEAGETRFTYATYGEGELPEGLTISSK
                     ESAETSDLLGSYLIVSGSLDGVSLQTTLKELGYQGFVSNGEDPFSIVLLLTATPMVLL
                     SLAIFLLTFMSLTLIYRIKSLRQAGIRLIAGESLFGVALRPVLEDVRQLICSVLVSSL
                     LGLGILWYQGALFMATVQLVIIALLLYGLTLAGISTLLSVVHLLGLQENSLVDLLKGK
                     LPLKRMMTLMMVGQLLAVLVVGSSATALLPHYREMQEMERASNKWSQSSDRYRLSFGW
                     SSAFADEEGTRKDNREWQTFTEERLANTDSFYIMSNVDNFSDGAEVDLDGNRLSDYTP
                     SGNVIYVSPRYLIEEKITVSSEFMDKMQNLSEGEFGLILPESLREQSVYYQGLFTDYL
                     QNFSSESVEVTSQKHYLPQVRLAFTETGQERFLYNDGYKTTRQYLKDPIIVVLTPQAT
                     GTRPVAGMLWGTTANSALKLDRYGDSITALKEQGLYHKVSYLVKSQLFFAKVLNDKRV
                     EFYSLLIGTILTLSTAILLFDSMNLLYFEQFRRELMIKRLAGMTIYELHGKYLLAQGG
                     VLLLGLVLSSILTRDGLISALVVALFTLNALLILVRQDKKEEAGSMAVLKGK"
     gene            complement(35103..35399)
                     /locus_tag="VXF95_000644"
     CDS             complement(35103..35399)
                     /locus_tag="VXF95_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1081230.1"
                     /translation="MKQTVKKLALVASIAATLGGSVAVASAAVQYPEGGVWTYGSGNG
                     GAYSNYYHPSKYHSSTVVSRKTGSSDKGYAGAGGTSRAWIRTSWGEKVAFYYNV"
     gene            complement(35719..36618)
                     /locus_tag="VXF95_000645"
     CDS             complement(35719..36618)
                     /locus_tag="VXF95_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1081231.1"
                     /translation="MLIGQKIKEIRIEKGVSRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLAYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(36690..37250)
                     /gene="rnmV"
                     /locus_tag="VXF95_000646"
     CDS             complement(36690..37250)
                     /gene="rnmV"
                     /locus_tag="VXF95_000646"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HEV1081232.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLVGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(37250..38023)
                     /locus_tag="VXF95_000647"
     CDS             complement(37250..38023)
                     /locus_tag="VXF95_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HEV1081233.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     RALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHPKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKDLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAVATTANAERIFGLDSK"
     gene            complement(38319..38993)
                     /locus_tag="VXF95_000648"
     CDS             complement(38319..38993)
                     /locus_tag="VXF95_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HEV1081234.1"
                     /translation="MTILGKDTVQQSAKGESVTQEATPEYKPETTLGVDKGGNTGSSD
                     ANANAGGGSQAGGPAHTGSQNSAQSQASKQLATEKESAKNAIEKAAKDKQDEIKGAPL
                     SDKEKAELLARVEAEKQAALKEIENTKTMEDVKEAETIGVQAIAMVTVLKRPVAPNAA
                     PKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALASLGLVAATSGFALLGRKTR
                     RRKWNS"
     gene            complement(39256..39390)
                     /gene="rpmH"
                     /locus_tag="VXF95_000649"
     CDS             complement(39256..39390)
                     /gene="rpmH"
                     /locus_tag="VXF95_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HEV1081235.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(39535..40749)
                     /locus_tag="VXF95_000650"
     CDS             complement(39535..40749)
                     /locus_tag="VXF95_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1081236.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLEIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(40905..41198)
                     /locus_tag="VXF95_000651"
     CDS             complement(40905..41198)
                     /locus_tag="VXF95_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081237.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMICQLESLVPLLYPSFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            41360..41812
                     /locus_tag="VXF95_000652"
     CDS             41360..41812
                     /locus_tag="VXF95_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HEV1081238.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIAHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(41847..43235)
                     /locus_tag="VXF95_000653"
     CDS             complement(41847..43235)
                     /locus_tag="VXF95_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1081239.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAADKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            43301..44263
                     /locus_tag="VXF95_000654"
     CDS             43301..44263
                     /locus_tag="VXF95_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HEV1081240.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVNTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
     gene            complement(44469..45479)
                     /gene="ccpA"
                     /locus_tag="VXF95_000655"
     CDS             complement(44469..45479)
                     /gene="ccpA"
                     /locus_tag="VXF95_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HEV1081241.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGIAYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
     gene            complement(45904..46503)
                     /locus_tag="VXF95_000656"
     CDS             complement(45904..46503)
                     /locus_tag="VXF95_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081242.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRAGYFERAVKAGVDAYVL
                     KERSVADLMQTLHTVLEGRKEYSPELMEVVMTRPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(46505..47602)
                     /locus_tag="VXF95_000657"
     CDS             complement(46505..47602)
                     /locus_tag="VXF95_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1081243.1"
                     /translation="MLERLKSIHYMFWASLIFMIFPILPVVTGELPAWHLLVDILFVV
                     TYLGVLITKNQRISWLFWGIMLVYVAGNTAFVAGNYIWFFFFLSNLLIYHFGVRSLKS
                     LHVWTFLLAQVLVVGRLLIFQRIEVEFLVYMLVILTFVDLMTLGSVRIRLVEDLKEAQ
                     VKQNTQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMQAYPQVEKELR
                     EIQQISKESMREVRTIVENLKSRTLTSELETVKKMLEIAGIEVETDNQLDTASLTQEL
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTIR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(47602..48339)
                     /locus_tag="VXF95_000658"
     CDS             complement(47602..48339)
                     /locus_tag="VXF95_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081244.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQAVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSAVLFGLTIYLQGHKENA"
     gene            complement(48341..49225)
                     /locus_tag="VXF95_000659"
     CDS             complement(48341..49225)
                     /locus_tag="VXF95_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081245.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(49212..49406)
                     /locus_tag="VXF95_000660"
     CDS             complement(49212..49406)
                     /locus_tag="VXF95_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081246.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLRQFIRGALGFGFM
                     IFVVFLMGMEWLKGESHDGG"
     gene            complement(49403..49609)
                     /locus_tag="VXF95_000661"
     CDS             complement(49403..49609)
                     /locus_tag="VXF95_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081247.1"
                     /translation="MGEEEMRNKMIIAVSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT        14345 a        11359 c         9540 g        14597 t
ORIGIN      
        1 acaaggaaaa agaaaggggt ttcacgaatg aagaaaaatc gtggaattca aaaattagct
       61 atattagtat tactaggtgt ttttatgttt agtaacacaa ttccttacca acagttattc
      121 agaagaatag acaattggag attcgagtgc aatcacaaaa gaagtccaat ggtcttgatg
      181 ttgggaaggc tgattgattt cgtattactt taaaattcaa ctatttagag aaaggtattc
      241 tgatgagagc ttgtaacaat accagataga tataagaatg gagatgtttg ataaaatgct
      301 ttcatagcta accaactgtt gaaaattatg agttacaaaa tctaaagtat ttaagattgg
      361 tttataaaat taggtctctg cctgtagaaa ggaacgtgca gttagaaagg aggaaaaaat
      421 aggatactat aattcagact gagatttcta attaaaatat gtagttgcat ttcgctcatt
      481 ttcataatat ttcatttaga ggagtaataa tatgttaaaa tttagaaaag tagttgcatc
      541 atcccttgcc gttttggcat ttagtttggc tcttcctgtt ttggcagttt ctcaccgtgg
      601 tggcgagtgg acctatggag gccatcatga tccatataat tggggagcat tttcgaatta
      661 ttatcatggt tcacagtatc actgggccta tgttggaagt aatgaacgtg acaatcaaaa
      721 aacagtttat gcaggagcac atagtgcggc ctatgcgttt gttaatacaa atttggggga
      781 gcgaattaca tttgatgcgg gatggtaaag aataattgaa gaagattctt ttatcaatag
      841 tttagtaagc ttgttagttt atagagggca ggggtatttc tgccctctgt tttagaataa
      901 ggaatgcact atgaaaaaat tatttatact catatccaac ctgcttgcta gtttgttctt
      961 tgtttgggta tttaccattt ggactgatac atatgtctcc cattattacc ccaacgttgt
     1021 tgtacatgat tcttcccctg aaacaacttt tcagcatgtt gctacacgct tggaaaaact
     1081 agcagaagaa acagatagct ttattgcgat tcaacaccaa gatcctaact cagaaggtac
     1141 tacagttttt tcttatacga cctttggaga cggaaagttg cctgacgggc tacaggaaaa
     1201 aaaactagaa gatgctcaaa gtagtagtgt tgaaacaaac tattttgtat tcgatggaca
     1261 cctagatatt cacttgctaa gggaggagct aagtcaactt ggcttgacta atatgcacct
     1321 gacaattcca tctaaactat ctacgttaat ggctatcttt agtaacggat ttcagttaat
     1381 cagtctattg attttcatct taacctttgg agcactgact ttaattagtc aaattagcca
     1441 attacggtcg tcgggcattc gcctcatttc aggagagaaa cggtggtcca tttttcttag
     1501 accagttggt gaggatttga aagggatagc tgttggtttc agtttagctg gcgtgctcac
     1561 cattcttatg caaaaaattc tgtcgcttcc aacgcaatcc ctaatgacca taggagcagg
     1621 cttgctcagt tataatctca tcttgttgtc tatctccctg tttttcgctc aactcttcgc
     1681 agttgggata aaaaagatac acctgatgca gattataaaa gggcaagtgc ctgtcagagg
     1741 aatcattagt ttgattttaa tcggtcaact attagcgatt attattgtaa cactgggaat
     1801 agggagtagc ttaaagtatt cccaagcctg gcaacagcat cggattggac aagaggcttg
     1861 gagccaggaa aggcaactga ttaccctatc aatcagccgt gaaggaacga gtcctggttt
     1921 tgatgaacaa gctcaaagga aactcagaac ttggtatcaa ttgatggatc tggctgtttc
     1981 agaacaaaag gctttcttat ctagacacca gttaattgac cgtactttgc aaaatggcat
     2041 ggcttcctcc aaaaacttta taacctctac agaatggcac gattacagcc cgaatggcaa
     2101 tgtccttatc gtcacaccgc aatacttgga gcgtcaaaac attcctgtag atacaactat
     2161 tgagcaaaag atgaatcacc ttgatgtagg ggagtttgtc ttattgctgc ctgaacacct
     2221 ccgttcagag gaagatcatt ataaatctgt ttttgaagac gacttaacca gtcgcatgtc
     2281 tagtcaagat gaacgacagc aaatgactgc tacggtaggt tatttagaat caggtcagga
     2341 tcgttttgtg tataatacga cccctatttc ttaccagcag tttttgaaag atccaatcat
     2401 cattgttata acaccccaat caactggtcc acagtccatt ttgttttgga tagacgcagt
     2461 acagaactac gttctcttta atcaattgtc tgatgcccag gagcttatcc agagacaagg
     2521 cattgaaaat tgggtctcag aaatgcaaac aggttaccac aactacatca cattattgga
     2581 taatatccag agggaacgtt gggtaatgct agcaggagct gtgcttggga ttgcaacttc
     2641 aatcttgctg tttaacacta tgaataggct ctactttgaa gaatttagac gtgccatttt
     2701 tatcaaacgc attgcaggtc tcaggttctt agaaatccat cgcacttatc tctttgctca
     2761 actgggtgtg tttttactgg gatttgttgc tagtgtattt cttcaggtag aaataggagt
     2821 tgctttctta gtcttgttac tctttactgg tctatctctt ttacagttac atgtccaaat
     2881 gcagaaagaa aacaagatgt ccatgcttgt tttgaaggga ggttaatatg attgaactta
     2941 aacaggtgag taaatctttt ggagaacgag agttattttc gaatctttca atgacatttg
     3001 aggctggaaa agtctatgcc ttaattggtt caagtggtag cggaaaaaca accttgatga
     3061 acatgattgg gaaattagaa ccttatgatg ggacgatttt ttaccgaggt aaagacttgg
     3121 ccaattataa atcgagtgat tttttccgtc acgaattggg ctacctcttc cagaactttg
     3181 gcttaattga aaaccaaagt attgaagaaa accttaagct aggtctcatt ggtcaaaagt
     3241 tgagtcggtc ggaacagcgg ttgaggcaga agcaggcttt agaacaggtc ggcctggctt
     3301 atcttgacct agataagcgc atctttgagt tatcgggcgg agaatcgcaa cgagttgcct
     3361 tggcaaaaat tatcttaaag aatccaccct ttattctggc agatgagcca acagcttcaa
     3421 tagacccagc aacctctcag ttgattatgg agattttgct atctcttcga gatgataata
     3481 ggctaatcat tatcgcaaca cataatccgg caatttggga gatggctgat gaagtgttca
     3541 cgatggatca tctgaaataa aaatccttgt ttttaattgc acgatgagtt actgaaatat
     3601 tatcatgaat caagaattgg agttaattta gaattgtact ttattaatat tgaggtaact
     3661 ttttcttgat aaaggaggaa atagtggaga ggaagttaga atgaaaaaat tcgacaatta
     3721 tattattgag aagccttgcg attctaattc agataaactg caaaaaatct taataattga
     3781 aaatttggta gatgatattt tgcaatttcc tctcagaatc aataatagtg taggagagat
     3841 tttcctccta caaccgtttc aaaagaaaac tatctttatt ccatgttatt ttgaggaaga
     3901 tattgtgaaa gtcaaagatg atgataaagt tgagtggaat ttgttagaat ttcaaaaatt
     3961 tagagcattt ttggcttagt aatctgtgtt gaaggctcaa aacctatggt aaaaaagtcg
     4021 ctttgaaaac gtattgcctc caaagattta gttaaataat gatttaacac aaaaagaaat
     4081 tattgaagtt ctggaaagat gttgtttcag tattgagaaa aggtgggaaa aacttgcgat
     4141 tttcacagag aaaggaagaa aaagtataga aatatagtca attgaaacaa gaacaggaca
     4201 aaagaacctt ttgtgccata tttttctcct ttcgctttac aattggcttg aacaccttta
     4261 ttgtatcgcg tttggagttt ttttggtata accttcgacg cgcacccgca tagcgggtgt
     4321 ttttttgtct cgcacctaac ggagcgagac gaactaatag tcacttaatc aaaaaaacgc
     4381 accatatcaa aaactaaaaa gtttgatatc atgcgtcatg tcttaaacta attgactata
     4441 ctttctattc aaatgagctt ttaaccaatt gattgagcca atccactctt aaaaccaaag
     4501 agcaatttct cgcttagctg actcttctga atctgaacca tgtacaacat tttggataac
     4561 ctcattttct ccagcagctt ttgcaaagtc acctcgaata gtgcctggta aagcttcttc
     4621 tggacgagtt gcacccatca tggtccgcca agtttcgatt actttgggac cagaaatgac
     4681 acccacaaga actggacctg aagtcatgaa ttcacgaatc ggtaggtaaa aactctgacc
     4741 aaccaagtcc tgatagtgct ggtcaatcaa ctcttctgaa acctgtgaac gaaactccaa
     4801 tttttcgatt gtaaatccac gttgttcgat gcgctttaac acttcaccca ctagccctct
     4861 ttttacacca tctggtttga tgataaagaa tgtttgttcc atacccgtct cctttgtcag
     4921 cttctttctt ttattttacc acatttcgtg gaaaaatgga gaaagttttc agaagagaga
     4981 atgagagaac ccgagggttc tctcattctc tcttattcta ctgtttcttc cacagtttca
     5041 acggcagtat ccacaactac ttctgttgtt tcttcatttc cttcttcctc tactgtagga
     5101 ttaaggtatt cttcttcgtt gacagcatgt ggttcaaggt tacggtaacg ggccatacca
     5161 gtaccagctg ggatgatctt accgatgata acattttctt taagtccaag gagatggtct
     5221 ttcttaccac ggatagctgc gtcagtaagg acacgagttg tttcttggaa ggaagctgct
     5281 gacaagaaac tgtttgtttc aagtgaggct ttggtaattc ccataaggac tgggcgacct
     5341 gtcgctggaa ctccacctgc gataaggaca tctttgttgg catctgtaaa gtcattgata
     5401 tccatgaggg tacccatgag aagatctgta tcacctggat ccatgacacg gactttacgg
     5461 atcatttgac gaaccattac ctcgatgtgt ttgtcaccga tttctacccc ttggctacgg
     5521 taaacttttt gtacttcacc gagaaggtac gtttcaactg acaagacatc acgaactgca
     5581 aggagacgtt ttggttggat agaaccttct gtcagagcag caccacgcgc tacttggccc
     5641 ccaacttcga cacgcatacg agctgtaaat ggaacgacat attcaccttc gccagtttca
     5701 cccttaacaa agactttctt ggtacgagtt gatgcatctt cttcgatagc agtaacttgt
     5761 cctttaacct ctgtgataac cgcttcccct ttaggattac gggcttcaaa gatttcttgg
     5821 acacgaggaa gaccctgagt gatatcggta tttgaggcaa ccccacctgt gtggaaggta
     5881 cgcattgtaa gctgtgtacc aggttccccg atagattggg cagcaattgt accaactgct
     5941 tcaccaactt caaccgcatc accagtcgcc aagttgatac cgtaacagtg acggcagaca
     6001 ccgtgacgag tgttacatgt aaatacagaa cggatagtca cttcttccac accagcattg
     6061 acaatttcac gcgccttgtc ttctgtaatc aattcatttg gaccaataat cactgcacca
     6121 gtttctggat gtttaacagt tttcttagtg taacgaccgt tgagacgctc ttcgagagac
     6181 tcgatcatct cttttccttc tgcgatagaa cggatcaaga gaccacggtc agttccacag
     6241 tcgtcctcac ggatgataac gtcttgggca acgtcgacca aacgacgagt caagtaacct
     6301 gagtcggctg tcttaagggc cgtatcggtc atacctttac gagcaccgtg agttgagaag
     6361 aacatttcca ataccgacaa accttcgcgg aagtttgaaa ggattggcaa ttccatgata
     6421 cgtccattcg gagcagccat cagaccacgc ataccggcaa gctgtgagaa gtttgagatg
     6481 ttaccacggg ctccagagtc catcatcata acgattgggt tcttaggatc ttggttagca
     6541 atcaagcgtt tctcaagttt ttcacgggca gcacgccatt cagctgtaac agcattgtaa
     6601 cgctcgtcgt ctgtgatcat accacgacgg aattgtttgg tgatttgttc gacacgtttg
     6661 tgtgattctt caatgatttc agtcttgtca tcaacgactg ggatatcggc aatacccact
     6721 gtcaatcctg caagagttga gtggtggtaa ccgaggttct tcatgcggtc aagtagggca
     6781 gaagtttctg tcgtacggaa acgtttgaag atttcagcga tgatatttcc aaggtttttc
     6841 ttcttgaatg gagggttgag ctcaagattg ctgatagctt ccttgatatc tccaccaagt
     6901 ggcaagaagt atttagctgg aacaccttct gtcaagttgg cattgtttgg ttcttgcaag
     6961 tatggtagcc cctctggcat gatatcgttg aagagaattt taccaactgt tgtaagcaag
     7021 accttatgtc tttgctcttc tgtccaaggc ttgttgaggc tgtctgttgc gataccaaca
     7081 cgtgagtgga ggtgaacata accattgcgg taagccataa ccgcttcgtc acggtctttg
     7141 aagaccattc cttcaccttc gcgaccagct tcttccatgg tcaagtagta gttacccaaa
     7201 accatgtcct gagatggagt aactaccggt ttcccatctt tcgggttcaa gatgtgctca
     7261 gcagctagca tgaggatacg agcttctgct tgtgcttctt ctgaaagtgg tacgtggatg
     7321 gccatttggt ccccgtcaaa gtcagcattg taggcttcac agacaagtgg gtgcaagcga
     7381 agagccttac catcaattaa gactggctcg aaggcttgga tacccaaacg gtgaagggtc
     7441 ggtgcgcggt tcaaaagcac tgggtgttct ttaatcactt cttcaaggat atcccagata
     7501 cgctcatctc cgcgttccac caagcgttta gctgctttga cgttttgcac gatatcacgg
     7561 gcaacgattt cacgcataac aaatggttta aagagttcaa tcgccatttc acgtggcaca
     7621 ccacattggt acatcttaag agttggacca acggcgataa cggaacgtcc tgagaagtca
     7681 acacgtttac cgagcaagtt ttgacggaag cgtccttgtt tacctttaag catgtggctc
     7741 aatgatttca atggacggct acctggtcct gtgattggac gaccacgacg accattgtca
     7801 atcaaagcgt caactgcttc ttgaagcata cgcttctcat tttgaacgat gatacctggt
     7861 gcatttaact caagcaaacg agccaaacgg ttgttacggt tgataacacg gcggtaaagg
     7921 tcattcaagt cagatgaggc aaaacggcca ccatccaact gcaacattgg acgaagatct
     7981 ggtgggataa ccggaaggat gttaagaatc atccattcag gtttgtttcc agacttgtaa
     8041 aaggcatcca aaacatccaa acgacggatg gctttgacac gtttttgtcc agtagctgtt
     8101 ttcaattctt ctttgagttc agcaatttct ttttcaagat ctacttgctt caaaaggtct
     8161 tggatggctt ccgcacccat cttggcaaca aatgaaccat aaccatattc acgcaagcgc
     8221 tctcggtatt cgcgctctgt catgatagac ttgtgctcaa gtggtgtatc cttaggatca
     8281 atcaccacat aagccgcaaa gtagataact tcctcgaggg cacgagggct catatcaagg
     8341 gtcaagccca tacggcttgg aatccccttg aagtaccaga tgtgagatac aggagctttc
     8401 aattcgatat gtcccatacg ctcacgacga actttcgtac gcgttacttc aaccccacag
     8461 cggtcacaaa caattcctct gtaacgaatg cgtttgtact taccacaagc acattcccag
     8521 tcttttgtag gaccaaagat cacttcatca aagagtcctt cacgttctgg tttcaaggta
     8581 cggtaattga ttgtttcagg ttttttgact tctccataag accatgaacg gactttactt
     8641 ggagaagcta gggtgatttg catactttta aaacgattta catcaaccac tatttcttcc
     8701 ctttctattc taagtgaact gcttattctt gttcagcagc ttcttctgtt gcttccgctt
     8761 ttgttgcttt ctcagcttct tcagcttcaa aggctgcttt agcctcttgg gctgcttttt
     8821 cgcgggcttt ttcaaggtca tctacgtgga tgacatcttc gtccattcct tcatccaagt
     8881 cgcgaagttc cacttcttgg tcatcttcgt ctaggacacg catgtcaaga ccaagagatt
     8941 gcaattcttt gacaagaact cggaaggatt ctggaacacc tggttttgga attggtttgc
     9001 cttttgtaat agcttcatag gctttcaaac gtccgttgat atcgtcagac ttgtaagtca
     9061 agatttcttg aaggacattt gacgcaccgt aggcttcaag agcccaaacc tccatctcac
     9121 cgaaacgttg tccaccaaac tgagctttac ctccgagtgg ttgttgggta acagttgagt
     9181 aaggtccgac tgaacgcgcg tgcaatttat cgtcaaccat gtggtggagt ttgatcatgt
     9241 acatgactcc aacagaaaca cggttatcaa atggttcacc agtacgtcca tcgtaaagga
     9301 tcgttttggc atcgctatcc atacctgctt ctttaacagt tgaccaaaga tcttcagaac
     9361 ttgctccatc aaagactggt gtcgcaatgt gaataccaag agtacgagct gccataccaa
     9421 ggtgaagctc cataacctga ccgatattca tacgtgatgg caccccaagt gggttcaaca
     9481 tgatgtcgac tggagttccg tctggaaggt aaggcatgtc ttctacagga acgatacgag
     9541 agacaacccc tttgtttccg tgacgtccgg ccattttatc tccgacctta atcttacgtt
     9601 tttgagcgat gtaaacacga accaacatgt taacacctga ttgcaactca tctccattta
     9661 cacgtgtaaa gatcttaaca tcacgaacga caccatcggc accgtgtggt acacgaagag
     9721 aagtatcacg cacttcacga gacttgtctc caaagatagc gtgcaagaga cgttcttcag
     9781 ctgaaagatc tttctcaccc ttaggtgtta ctttacctac aagaatatca ccttctttaa
     9841 cctcagcacc aatacggata atccccattt cgtcaaggtc tttgagggca tcttcaccaa
     9901 cgtttggaat ttcgcgagtg atttcttcag gcccaagctt tgtatcgcgc gtttctgatt
     9961 cgtattcttc aaggtgaaca gatgtgtaga catcgtcctt caccaagcgt tcgctcatga
    10021 taacggcatc ctcgaagttg taaccttccc aagtcatgta ggcaacgatt gggttttgtc
    10081 caagcgccat ttctccattt tccatagaag gtccgtcagc gatgaaatcg cctttttcaa
    10141 cgacatcacc aacttttacg agagtgcgtt ggttgtaagc agtacctgag tttgaacgac
    10201 ggaatttttg gatgtggtaa acatccaatg aaccatcttc acgacgaact tctaccttgt
    10261 cagcatctgc gtaagtaact ttaccatcat actgagcaat cacagccgca ccagaatcgt
    10321 gggctgcttg gtattccata ccagtaccaa cgtaaggtgc ctgaggatta atcaatggca
    10381 cagcctgacg ttgcatattg gctcccatga gggcacggtt ggagtcatcg ttttccaaga
    10441 aaggaataca tgctgtcgca acggcaacta cctgttttgg tgaaacgtcc atgtagtcaa
    10501 caatattagc tggatactct tggttgaccc cttggtgacg tcccatgaca atcttctcag
    10561 caaaggttcc atcttcattc agacgagagt tagcctgagc tacagtatat tcatcttctt
    10621 catcagctgt caaccaaaca atttcgttcg tgacaacacc tgtttcacgg tcaaccttac
    10681 ggtatggtgt ttgaacaaaa ccatatttgt tcaagtgtcc gtaagatgac aagttattga
    10741 tcaaaccgat gttaggtcct tcaggtgtct cgattggaca catacgacca tagtgagtgt
    10801 agtgcacgtc acgtacttca tatccggcac ggtcacgagt caaaccacca ggtcctaagg
    10861 ctgacaaacg gcgtttgtga gacaactcag aaagcgggtt gtgttggtcc atgaactgtg
    10921 acaactgtga tgaaccaaag aattctttaa ctgcagctgt tacaggacgg atattgataa
    10981 tttgttgtgg tgtcaagact tcattgtcct gaacagacat acgttcacgg acattacgtt
    11041 ccatacgaga aagtcccaaa cgtacttggt tggcaagcaa ttcaccaacc gcacggatac
    11101 gacgatttcc aaggtggtcg atatcatcta cacggccaag tccttcagcc aagttgagga
    11161 agtagctcat ctcggcaagg atatctgcag gagtcaccgt acgaaccttg tcatctgggt
    11221 tagcattacc aatgatcgtt acgacgcgat ctggatcagt tggagcaaca accttgaatt
    11281 tttgaagaac aacaggctca gtcacaacgg ctgcatcgtt tgggatgtag acaatcttgt
    11341 tcaagtcgcc atccaaatgg ctttcaatgc tttcaatcac gctacgagtc ataatcgtac
    11401 cagcttctac caagatttct ccagtttcag ggtctaccaa tggctctgca atggtttggt
    11461 tgagcaaacg tgttttaaca ttgagttttt tattgatttt gtaacgacca actgctgcca
    11521 agtcatagcg acgtgggtca aagaagcgag ccacaagcaa gctacgtgag ctttcagctg
    11581 tcttaggctc acctggacga aggcgttcgt aaatttcttt caaggcttcg tctgtacgag
    11641 agtccattgg attcttgtgg atatcttttt caacagtgtt gcgaaccaat tcgctgtcac
    11701 caaagatatc aaagatttca tcatcacctg agaaaccaag agcacgaacc aaggttgtaa
    11761 atggaatctt acgagtacgg tcgatacgag tgtaggtgat atcttttgag tcgctttcaa
    11821 gttccaacca agctccacgg ttagggataa cagttgaacc atagcccacc ttaccatttt
    11881 tgtctacttt gtcgttaaag taaacacctg gtgagcggac caactgagaa acgataatac
    11941 gttcaccacc attgatgatg aaagtaccca tttctgtcat gattgggaaa tcaccaaaga
    12001 aaacttcttg ggtcttgatt tcgcctgttt ctttattgat caaacggaag gttacaaaaa
    12061 ttggtgctga gtagctagca tcgtggatac gagcttcttc tagcgtgtat tttggttcct
    12121 tgatttcata tccaacaaat tccaactcca ttgtgtctgt gaagtttgaa attggcaata
    12181 catcttcaaa cacttcctta agaccgtggt ctaggaaagc tttgaatgag tcagtttgaa
    12241 tttcaatcaa atttggtaag tcaagaactt ctttgattct tgaaaaacta cgacgggtac
    12301 gatgtttccc gtattgaacg tcatgtcctg ccaagatgat tctcctttgt aaataagttc
    12361 caagccttgt caatcaggct tttctaatcg ccatatggtt gtaaacccct tatcaccgtg
    12421 tcctcttgac gaattttcag aatctttaag cctctgttac aaatgctcaa aatcttgaaa
    12481 aaaagcacaa aaagagcagc taaatctgac tttttcagaa gatttaactg ctgtgagcct
    12541 tgtctggaca atatttcaga caaaacctac gacaaatgat tacccatatt ataccctatt
    12601 tagctagatt tttcaagggg tttcagtagg tttttggtaa attttttccc atagaaaact
    12661 tggcatcaca ttcgaatcac gctatggtac aaaaaactga aaaaactatt gactgaaaat
    12721 cattttcaag gtataataat aaacgttaag gcggtatagc caagtggtaa ggcacggctc
    12781 tgcaaaagct tgatcgtcgg ttcaaatccg tctaccgcct tctataactt gatttatcag
    12841 gtttcaaatg aacagaaagc ccaatttgaa gggcttttct tattttccct cgaataaata
    12901 cgtataactt taaaaacttt tggagcgagt ttgtggcaga gttctttcca tggcataatt
    12961 cccttttgaa atcaattgaa aaaagcttcg tcacgcctgg tgacaaaagc ctctagttta
    13021 ttctgtttct tcttctattt cgacttctgt gatttggatt tttaccttgg taacacgtcc
    13081 attcttcact ttatcattgg ttaagataaa ctgtttgttt tggctgatca attcatagct
    13141 gagtttctca gtcgttggaa tggttcccac tcctgtcaaa taataaccag cgatagtatc
    13201 aacgtcatca ctttccagtt caacattaaa gtaattattg aaatcattga gggtcatagt
    13261 tccttgaaca atgtaggtat cctcgccaat ctgataaaca tctattgctg ctttgtccgt
    13321 ttcatcatca atttcaccaa caatttcctc taagaggtct tccaaagtca ccaaaccagc
    13381 cataccaccg tattcatcca gcaagattgc catttgtctt tgggtatttc gcagttcttt
    13441 tagcaagtca tccacaaaaa tagtttcagg tacaaaaagt ggatcttgta aaattctctt
    13501 ccaaacaata ttgtcaaaac cgtccacaaa gcctgcctta aggagactct tggtgtgaat
    13561 gattccaatt acattgtcct tatccccatc ataaaccggg atacgagaat aattttgttt
    13621 taaaatactt tggataatgg cttgactatc atcctgaata tccaccataa aggcatccgt
    13681 tcgaggaacc ataacctctc gtgccatcag ttcatcgagc gaaaagacac cttgtagcat
    13741 ctcaatctca tcagcatcca atgtttcttc actatttgtc agcatatagg caatttcatc
    13801 acgggtcatc ttttcatccg catcatcgaa tgacatagga gtcaaatggc tcaagaaatt
    13861 ggtcgaagca gctaaaagcc aaacaaaagg actgactagt tttccgatcc caatgataac
    13921 cggcgctgta cgaattgcca aggcatcctt tagattaaga gcgattctct taggatataa
    13981 ttccccaaaa acgatggaaa tataggtcaa aaatgccaag gatagaaaag ttgccacggc
    14041 ttgtgctgtt tcgccattcc caagccaaga ggcaatcaca cgtcctagag tatcagttaa
    14101 actcgcccct gataagattg taatcagggt gattcctacc tgaatggttg ataaaaagtg
    14161 gttaggattt tctagtacct tcagcaggcg gatgtagcgt ctgtctcctt cttccgcctt
    14221 ttgttcaact cgggcacgat taagagaaac catggccatt tctgtggctg agaaaaaggc
    14281 atttaatacc gtcaagataa acaataaaac aaattgtagc aacaaattct gactacttgg
    14341 gtcttccata gttcttctcc taaaatagta tcttatcctt tattatatca caaaatttaa
    14401 tccaatacat attatttttt tcttagcgta acttccatct ctctcccaaa actggaagtt
    14461 agtctaagac ggatttccac tgatttcacg cgtttttctc atactaaaag ctaggttgtg
    14521 ggaaactgga agttagtttt agaagttgct attttttctt agtacctgtt ctagccctgc
    14581 ttaaactagt aaaaagaact cctacatcca taagtgacat aggagtttag gcttatcttt
    14641 tactgagtta cagttacttc tccagttcgg taatccagtt gaagtccctt ttgaacattg
    14701 ggaactagaa cattgaattc caattctcca tccgaagact tggcttcaat ctgtgaagct
    14761 gagggaacta aatcctcgtt tgaagcgtag taaagggtta cacggtaacg gacacgcttg
    14821 ttttggtcca aggctttacg caccttgctt tcatagtagt tttgaccagt cgaatactcg
    14881 gcttgtgcct gatttgccca ggctgtctga acagcaatgt ttttaggatt gcttgttgag
    14941 gcatcaaaac catccaaacc accgattaag gcatagccta acaaatgacc tctatcgact
    15001 gcatgggtat aagagccctt tagattcttg acctgatgcc aacctggagg agtccaagaa
    15061 gttgaaccat tcccagtttc tttacgattc ttgtactgac gagtggcatt agacaagagg
    15121 gcattagcta cggttggaac agtttccttg cccactgtct ttgttttatt gtcagcgtag
    15181 ggcttacttg aaaccttggc atctagattt gttttattac cattgacgat aaaagcacct
    15241 gagccattcc actccagact cccctttatt tgactcttga ctgcgtctgt taagacactc
    15301 tctgccaatg cttgactagg agcttcaggc gcttgttttt tctgactaag attggttttg
    15361 ggactattag gtgccgactg catctgcttg atataatagc tccctgtaga caaaagcaat
    15421 aacactagca gtccgattag tgtctgtctt gtttttttgt tcatatttct ccttatcttt
    15481 agaaaaaggc tggttctcca gcctaatttc ctgtaaattt atgaatcaat tcctgccatt
    15541 ttgctggaga caggatagcc catggatctt gacccttgcc caagattcca taacctacca
    15601 ttagaccgat tcctagagcc agagtaccta aaatcagtac tatgatgact aaaagtaaac
    15661 gcttgactac gtagcttgat ttcttattca tcttcatcac ttgcctcaat ccgctgaatc
    15721 ttagcaccta gctgcgccaa cttctcatgg aaaccgtagt aacctctatc caagtgaacc
    15781 aatttaccga ccacagtttc tccctgtgct accaaacctg tcaaaatcaa agctgcactg
    15841 gcacgaaggt cagttgaaag aacttctgct ccctgcaaag gctgtccacc aacaatacga
    15901 gctgtatcac ggataatctc agaatgcaag cccatgcggc gcatctcttc taggtgttgg
    15961 aaacgatttt caaaaactgt ctccaccatg gttgattcgc cttttgcaac tgtcatcaag
    16021 gctgtaaatt gagcctgcat atctgttgga aatcctgggt ggggcaaggt tttcacatga
    16081 acagctttta gattttccag ttgagaacga acacgaattc cttcgtcttc ttcaattact
    16141 tcaacaccca tttcaagtaa cttggcaatc aagggacggt tgtgctccca gacagcgtct
    16201 cgaatcaaga catcaccacc agtcatggca gcagctacca taaaggttcc tgcttcgata
    16261 cggtcctgga ctacattgtg agtcgtacca tgaagtttct caacaccagt aatggttata
    16321 gtctctgtac cagcaccttt gaccttggct cccatttcat taaggagaat ggctaagtca
    16381 acaatctcag gctcacgcgc agcattctca atcactgtca ccccatcagc cagagtcgct
    16441 gccatcatca agttctgcgt tgcaccaaca cttggaaagt ccatatagat atgagcacca
    16501 tgcaagcgtt ctgccttggc ttcgatgtaa ccagctgtct gactaatctt aacccccata
    16561 gcttccagac ctttcaaatg aagatcaata ggacggctac caatcgtaca accacctggc
    16621 atggatacct tggcatgacc cacacgggca aggattggcc ctaatacaac gatggaggcg
    16681 cgcatcttac tgacatactt gtaaggggct tcctcagtga tgtcgccagt agcatccacc
    16741 ttgacaagat gagcttcctc atcaaagtca accttggcat tcaaaccacc aactacctga
    16801 ttcataataa agacatccga caaaatcgga acattctgca agacggtctt tccttcactt
    16861 gctagaatag tcgctgccaa caagggtaag actgcatttt ttgctccctc gatcgtcacg
    16921 cttcctacca gacgattatc gccaccttga accacaattt tatccatact cgtttccttt
    16981 actcttgatt ttataataat cctctaagcg cttcttgcca caaatgatac aggctaataa
    17041 agaaagaact caggatgtag cctatgacaa tgctaaaaaa ggctactaat acacgaactt
    17101 ttcttgtatt ctcagctgtc acttttaaaa ccttttccca tctaacaaga tcctttaaaa
    17161 ggtaaaaact cacataaata aagagcatat gactacttag agtgaataat aattgaacca
    17221 tttgactatt ataccatctt ctctgtttgt gcgctagttt ggaaacttca ctcaaaaatt
    17281 agggattgtt tttcaagtaa tcaatcgcat cttgtagggt tttaacgggc acgattttca
    17341 tatccgtctt gattgtttta gccgcttcta gggctgtttg gtagttgttt ttcgcgtccg
    17401 gatgcgcctt ttgttcttct tcgctaacag ggttatcagg agcaaagaaa atagcagcac
    17461 ctgccctagc cgaagctaca accttcttat caatacctcc aatgtctccc acattaccat
    17521 cgcggtcaat ggtacctgta ccggcaacaa tacgaccatt acgaagatct gggtgagcta
    17581 tttgagtata gatagctaga ctaaacatga gaccagcact tgggccgcca ataccagctg
    17641 ttgaaaagct aattgggaca ttgctgatta cctctgtacg atcaatcaag ccgattccaa
    17701 tcccattttt tccattttcc aaggtgataa tctttccttc tgcagacttg gtttgcccat
    17761 cctcttcata ggtgaccttg acggagtccc ctaatttttg agaactgacg taatcaatca
    17821 agtctttgga actatcaaag gtctgatcat tgactgctgt gactgtatca gagatattga
    17881 gaatcccttt aaaggttgaa ttatccgtca cattcaaaac ataaactcca aagtacttga
    17941 gttcgatatc cttaccagct gtttttagtc cttgatactt ggccatattt tgcgatgttt
    18001 gcatgtagaa ttgattgatt cgcataaatt caacatcgga agaaccacct gtagtctcct
    18061 gagcactacg aatatctgta aaaggtgtca accaagcata aatcatatga gctaaagtag
    18121 catgttgaac accaaccgta acgaattgat aggcaccagc ttccttatct tctgtgtcat
    18181 ttactttaag gacttggcga atatcttccg aaccacctgg aacctctata tagtagggca
    18241 aaggcaccac aaatgccaag aaggtcacaa tcaaggccgc aatgacatac aagggccatc
    18301 taatcttttt tttcatttct tatttcctcc aaaatactct cgggaacatg gcaggcaata
    18361 tcctgaccaa acttcaaaag ctctcgaaca cctgatgaac tgatatagag atgttcaggc
    18421 cggctatgta aataaatagt ctctatatca gaagacagct gatgattgta gtaatcaaaa
    18481 ctagcttcat attgcaaatc cgccgcattc ctcaaccccc gtactaggaa agtagccccc
    18541 agtctttttg caacatcgac caccaattta tcatgagaag ccacgacttc aacattttcc
    18601 aaatgtccca aagccttttc tagcccccgt ttacgatttt caagagggag aaatccttgt
    18661 ttgtggggat taaaaaaaat acccacataa agcttatcaa aaagtctgct cgcccgttca
    18721 atgatatcca gatgcccatt tgtcatcgga tcaaatgagc ctgtgaataa gccaatctta
    18781 tctgacatag actgtcacct tactaattcc ataaatcttt tccttccaga tacccagaca
    18841 ggcaatttct tctggaagtt caacggcttt atccgtctcg cacacaacca taacatcttc
    18901 agaaaaaagc tctctctcag ccattttttc aatatctgct acgatttgtt ccttggcata
    18961 gggagggtct aagaaaacga ggtcaaattc cccagatacc tgttccaatg ccctttctgc
    19021 atccattttg aggagttgaa attttccaac ttccttggtc atctggatat tttcagccac
    19081 gatggtctga gccttacggt ctcgctccac caaaacagca ctggacatgc cacgcgatac
    19141 tgcttcgata gataaaccac cactacctgc ataaaggtcc aagactcgtc ccccttcaaa
    19201 gtagggacca atcatgttaa aaatggctcc cctaacctta tccgaagtag gtcttgttgt
    19261 cttgccttct agtgtcttaa ggggacgtcc cccatagatt cctgatatga ttttcatact
    19321 gtttattata ccaaattata gacaaaaaga gaaagaaaac cgaaccttgc ggttcgattc
    19381 tctacaaaat attttcgtaa gtatcgcgga cttcttgagg ccaaacactt gtttgcactt
    19441 ctccgatgtg tctcttgcga agtaggaaca tggccatacg agattgtcca attcctccac
    19501 cgattgtcaa tgggaatagg ccattcaaca aagacttgtg ccattccaat tccaagcggt
    19561 cttcatcacc tgtaatttcc acctgacgtc taagagtttc ttcatctaca cgaattccca
    19621 tagaagacaa ctcaaaggct ccacctaaag actcattcca gacaagaata tcaccattta
    19681 gacccttgta gccattctca gactcgcttg tccagtcatc atagtctggt gcacgtccat
    19741 cgtgcggttt accatctggc aactcgccac cgataccaat caaaaagacg gctccaaatt
    19801 ctttacaaat cgcattttca cgttctttcg gtgtcaagtc tgggtagcgt tctaccaatt
    19861 cttctgtatg gataaaggtg atttgttttg gcaagataga ctcgatgtca tagcgggctt
    19921 caacagctag ctcagtcagg cgaatagcct tataaatctt ctcaactgtt tcttttagat
    19981 aaacgatgtt acgcttacca tttgggataa ccttctccca gtcccactgg tcaacataaa
    20041 cagagtgggt tgcatccaag gaatcctcat ctggacgaag ggctttcatg tggacaaaga
    20101 gaccctctcc ttcaccaaag ccaaaacgag ccaaggtgtg gcgtttccat ttagcaagtg
    20161 agtgcaccac ttcataagta gcatcaggga tttggagaac cttgaccgat actggatttt
    20221 ccacaccaga caggttgtcc tgcattccgt caccgacctt actcaagata ggaccttgaa
    20281 cttcgacaac ttctagctta tctttcaaat actgggtaaa agtgtttttg acaaaggaaa
    20341 tttcttcttg ttgatggata aaacttttct tcatagacaa ctcctcaaaa atttaataaa
    20401 cgtattatac acctatttcc aagaaaagaa aagagaaaat ttaaaaaaaa atcagtgtca
    20461 ctcaaaacac tgatttcata gaccttttag tcattgcgac caaagatacg tagaatactt
    20521 aggaaaagat tgataaaatc aagatagatg ctgagagcca ttgacaccac ccagcctgtc
    20581 gctacacgac cttgtgattg ttcataggcg aggcgaatct tttggttatc ccaagcaatc
    20641 aaccctgaaa aaaccaaaac catggctacg ctaatcatat aatcaaagaa gccactagcc
    20701 aagaaaatat tgactaccat agcaatcagt aaaccaatga gagctgccat cattgctcga
    20761 ccaatcccac tcaagtcttt cttggtaaag ataccaactg ccgccatgac aaagaagaga
    20821 agggcgctcg atacaaaggc agataaaact gtacccggag tatagaaagc caccacaaaa
    20881 ctaagggtaa agccgtttaa aacggagtaa agtaaaaata ctggaagagc agctggacta
    20941 tttcttgaag ccatactact ggcaacgaaa accaaagcca actccgcaaa agtagcaatg
    21001 gtcaaccaga gacgcccctg catcaacaag taaaccaact gagactgaaa gaccgtcaac
    21061 ataaggcctg ataccaaagc agatagtccg attcccagac caacaaaggc ataaacctta
    21121 gcgtaaaatt gattgagacc tgcacggtca tgtataatag tgtgattcat ccttttctcc
    21181 ttttctgtga acatctttcc ttgattataa caaaaaaagt taaaattagc ttaaatggaa
    21241 gattaaaata ccggctgcaa ctgcaacatt caaactctcg gcctgcccct tcatgctaat
    21301 atggaccaac tggtctgcac tttcagccat aaggggacta attccttgac cctcatttcc
    21361 cataactagt acaaaatttt ctatagaagg cagttctctg taatcaacag aatctttaga
    21421 tagggttgtt gctagcactg ggatagctac ctttttagtt tcgtcaagaa gcgcttgact
    21481 agtcatccgg taaatgggca gatggaaatg actaccttgc atggaacgta gggttttgag
    21541 actgtagatg tctgccgact tatctgaaac aatcactcct gtaaaacctg ctgcatccgc
    21601 agttcgaatg atagttccta cattaccagg atcttgcaca tcttccaaaa acaagaactt
    21661 gccctgactc aaatcagctt gtcctacttc ttctttttga accaccgcca caattccctg
    21721 tggagtctga gaatccgcca aatctagcaa aatatcctct gaaatccaga cagtttgcgg
    21781 aaaagcagct aactgatctc gataattttc tagggcaaag attttctcaa tcgtcactcc
    21841 agcttggaca gcctcttcaa acaagtgcca gccttcaatc aaataggcag acttgcggta
    21901 ttttttttgg tgtaatttct tggcattttt taccacagaa ttggcttttg aggttataat
    21961 agtcatagaa atattataac acaatcaaag gggtttggta tgcaaaaggt tagaatgatt
    22021 gcccaaggta gggtacaggg agtcggcttt cgttggggtg tttacagctt ggcacttgaa
    22081 attggtggca tcacaggtcg agtatggaat aacgacgatg gcacagtgga aatcttagcc
    22141 caagcagact catctgctat catggcaaaa tttatccaag aaatccgaaa aggaccgaca
    22201 cctttttcaa aagtaagcta cttagatgtc aaactaagca actttcctcc ctactctgac
    22261 tttaaaatcg caaattaggt ctccagaact attgtatatt ttgtaaaaaa acagtagaat
    22321 agaaaggtat aatttttaaa gaaggaataa aaacagtgaa atctattaaa cgttttgcat
    22381 tctcggctat gggagtggct atgttgcttg tcttgactgg ctgtgtcaat gtcgataaaa
    22441 ccacaggtca gccaacagga tttatttgga ataccatcgg agcgcctatg gctgaagcca
    22501 tcaagtactt cgctactgat aaaggtctag gctttggtgt cgctatcatt atcgtaacca
    22561 ttatcgtacg cttgattatc ttaccacttg gtatctacca atcatggaag gcaacgcttc
    22621 actctgaaaa gatgaacgcc ctcaagcacg tccttgagcc acaccaaacg cgtctcaaag
    22681 aagcgactac tcaagaagaa aaactcgaag cccaacaagc tctctttgct gctcaaaaag
    22741 agcacggtat cagcatgttt ggcggtgtag gatgtttccc tctcctcctt caaatgcctt
    22801 tcttctctgc tatctacttt gctgcccaac atactgaagg ggttgctcaa gcaagctacc
    22861 taggcattcc tctaggttct ccaagtatga ttttggttgc ctgtgctggt gtcctttact
    22921 atcttcaatc gctcctttca cttcacggag tagaagatga aatgcaaaga gaacaaatca
    22981 agaaaatgat ttacatgagc ccactcatga tcgtcgtctt ctccctcttc tcaccagcta
    23041 gtgtcacact ttactgggtt gtcggtggtt tcatgatgat tctccaacag tttatcgtca
    23101 actatatcgt tcgtccaaaa cttcgcaaaa aagtccgtga agaactggca aagaacccac
    23161 caaaagcaag tgctttctca acaccaagtg gacgaaaaga cgttacccct gaacaaccaa
    23221 ctgctattac aagcaagaaa aaacacaaaa atcgcaacgc tggaaaacaa cgttcgagat
    23281 aagaagaaaa aggcttagct gatttgctaa gtctttttgc aagtcaaaag cccgatgttt
    23341 ccatcaggct tcttttctat ccatgtacac gtttcatata atcttgataa ctttcggtat
    23401 ccatgagttg tttagcgttc ttgacgcgat ctgctgttgg tggtttgact ccttcgaggg
    23461 aatatggaat tccaagttca cgccacttga actcacccat ggtgtgataa ggtagaattt
    23521 caaacttatc aacatttttg agggtcttga cgaacttacc aagttcaatc aagtcatcat
    23581 ctctgtctgt caatcctgga actagcacgt ggcgaatcca gacaggtttt ccaatatctg
    23641 atagatactg ggcacaagcc aagatatttt tattggtttg gctagtgaca atcttgtgct
    23701 gttcttcgtt gatttccttg atatccaaaa gaaccaagtc agtgacagcc atgagtttgt
    23761 caaacttctc aaggtaacgt ggtttattac ggaaaggaag agcacaagtg tccaaggtac
    23821 agtggattcc ttgttcctta gccttggtga agagggcaat caggaaatca atctgcaaga
    23881 gagcttctcc tccactgact gtaatcccac ccttatttcc ccagaaacca cggtagcgca
    23941 aggcctctgt caagacatca tctaccgtcc gttcacgtga cttattggac tccatagccc
    24001 aagtgtctgg gttgtggcaa tactggcaac gcatgtgaca gccctgcaaa aagacaataa
    24061 agcgaatacc gggcccatct actgacccaa agctttctgt cgaatgcacc attcctgtca
    24121 cttgtccata atcaattgtt tcttcagaca tatcgttacc ttccttgaaa acgttttata
    24181 gttttattat atcacgactt gaaggaaaaa caagattttt gcctattttt tagaaagcaa
    24241 tctgtttttc aatttcattt tcaatctatt atcagattat tcttcaaaat cgaagccata
    24301 taaggttgca aaatagtcct cagggcgctc tgcacggcgg atttgacggg ctttaccttc
    24361 ttcggtatag aggatttccg cagaacgtaa tttggcatta tactggtagc ccattgaaaa
    24421 tccgtgggca cctgtatcat gaattaccag caaatcaccg atttctgtat gaggcagttc
    24481 gcgattgact gcaaatttat cattgttttc acagagtgaa ccaaccacat ctaccgcttc
    24541 agctggtcca tctggatggg tcacgttgct aatatgatgg taagctccgt acatagctgg
    24601 acgcatgagg ttgactgctg aggcatctac acctagatag gtacggtagg tttccttctt
    24661 atgagtgact cttgtgacta gagcaccgtg aggtgccagc ataaaacgac ccaattcggt
    24721 gaaaatcttg acctgaccaa gacctgctga cgtaagaact tcttcataca ccttacgaac
    24781 tccctcacca atcaaggcga tatcgttcgg ctcctggtct ggacgataat taacaccaat
    24841 accgccagaa agattgataa agtctaacga aatgcccaac ttttccttga tttcaacagc
    24901 cagttcaaag agctgacgag ccaactctgg ataatagaga tgggtcacgg tattggacgc
    24961 taggaaggag tgaagcccaa aagtcttggc tcctttttcc ttcaagatag caaaggcttc
    25021 aaagagctgg tccttggtca tgccaaactt agcctcccca ggattgtcca taatgtctgt
    25081 ccccagttca aaaacgcctc caggattata acgacaagag atgatttctg gaatgcctgc
    25141 tactctctcc agatgttcaa tatcttcaaa ggcatccaag ttaatggtcg cacccaattc
    25201 acgtgcatag gcgtattcct tgtctggcgt gttgttggaa gagaacataa tctcagaacc
    25261 cagaaagtcc agtttatggc tcatcaaaag ctctacataa ctagagcagt ccacaccaca
    25321 accttcttct tggagaattt tcaaaatagc tggagttgga gtagccttaa ctgcaaaata
    25381 ttccttaaag cccttgttcc acgaaaaagc ttggttgaca gctcttgcct tctcacgaat
    25441 ccccttctca tcatacaagt gaaagggagt cgggaactcg gcaacaatcg cttctaactc
    25501 ttctctattg ataaatggtg ttttcataag cttccttcta ttctgtttgc aaagaaaggc
    25561 tgggacaatc gttccaacct ttagttctat ctcttattta tcttcgtcaa agatattgcc
    25621 aacctcaaca tcgatggctt ggttcttgac atcaatatta gttaccttca agagtgactt
    25681 gtagtcaaac tgcttttcac gttcttcttg ggcattgtcc gcaaagaccg ctacacctgc
    25741 cagttctgag tcgaactcgc gcaagagact aatcataccg ttgaccgttc cgccaccttt
    25801 caagaagtca tccacaatca agacacggct gcctgcctta agactacgtt ttgaaaggaa
    25861 cattttctcg atacggtcac cacttgaacc tgaaacatag ttgacgctaa cagttgaacc
    25921 ttcggtaatt ttcaggtcac ggcgcacaat gacaaaagag acattgagga cattggcaac
    25981 tgcatttgca agtggcacac ccttagttgc tacggtcata accgcgtcaa ttttttggtc
    26041 cataaagctt ttggcaataa tacgaccaat atttttcaag atggctggtg tgctaagcaa
    26101 atcagacaga tagatataac cacctggcaa gatacggtca ctttctgaca acttggtacg
    26161 caagtcttca accatttcct tagcatcctg actcgaaata gacggtgtga agatgacacc
    26221 tccgccagcc ccagtcactg tctggatatg accgatttca atttcctcaa aggcgcgttt
    26281 gataatgacg atatcttctg agatggatga tttagcagac tcatactttt cagcaaaagt
    26341 attgagacta gttagtttat aaggattatt aatcaaatag ttggaaatga caaccatccg
    26401 atcacttctt cttaatttca tttctatttc ctattccatt tttattcaaa aaatcaaaaa
    26461 gcaaactaga aagctggtcg ctggtggttc aaaacactgt tttgagattg tcaatagaac
    26521 tgacaaaccc tgtaatatac ctgcatatat acatacgaca aagcgatact accctagttt
    26581 gaagagattt tcgaagagta ttcatttttg tcttttactt attataccat attcacataa
    26641 aaaaacgaac attcttatcc taaaaaatgc tcatttttct taaattatca atctaaatct
    26701 ggtttataga aggaacgatt atccatagcg aagattttat tggacatctc tcctttatcc
    26761 accaaagcca gagctgttga catcatcatc atgcttgcat ccagattgtc aatcatatgg
    26821 ataatctctg cctccataat acgtggacgg actggacttc catattcaag caagccgtgg
    26881 tgactgagga tgacatgacg aagcaaaacg acttcttcct tggtatcatc gatgccgagt
    26941 tccataactg tcttggtaat ttcgctatca atgagagcga tatgtccaag aagattacct
    27001 cgcactgtgt actctgtctg gtctggcccc gtcaactcga taaccttagc taagtcatgc
    27061 agcataatcc ccgcatagag taagctctta ttgagctgag gataaacttc gctaatagcg
    27121 tctgccaaac gtaccatggt cgccgtatga taagccaagc ccgtttcaaa ggcatggtgg
    27181 ttggtcttgg cagctggata ggagtagaat tccttatcat acttggtgta gagatttcgg
    27241 acaatccgtt gccagacagg attttcaatt ttgaaaatca tttgcgacat gtagtcacga
    27301 atttccttga catcaactgg tgacttgacc ttgaaatcgg ctgggtcatt gggttcacca
    27361 gcttgaggca ggcggagagt aatttgattg acttgagggg tattgttata aacttctcgg
    27421 cgtcctttca tgtggacaac cttacctgcg gtaaaggcct caatgttatg aggttgggca
    27481 tcccagagct tcccatcaat ctcgccacta tcatcttgga aggtaaaggc taggtagttt
    27541 ttcccagctc gagtttgcct caggtcagct gatttgatta ggtaaaagcc ttcaaatagc
    27601 tcatcttttt tcatgtgact aatcttcata ttcttcctca ttttcttgaa aatggagtag
    27661 atcaagcgca ggctcgcctt ctgacaactc aatgtgacgg agcgtccgct cgatagctat
    27721 ggtacgacgg tttaataatt catcaatatt gccagaggca tgttggagat gtttttgtgc
    27781 cttgaccaga ataccaccaa acttgccaaa ctcggtcttg acactggcaa gagtcttgct
    27841 gatatggtcg gcactctttt ggatattaag ggtcttgaaa ccaactgata gggagttaag
    27901 aagggctgat agggtacttg gtcctgcaac gataatctgt tcttcccgtc tcaaatcatc
    27961 aaagaagacc ggattgcgga cgatttctga gtagagacct tctgtcggaa caaacaaaac
    28021 tccaaaattg gtcgtccgag gtggtgctat gtacttgttc ctaatatccc tagcaaaacg
    28081 cttgacactt gctaggagtg acttacgaca gcgttcgatt tcatccttgt cacctacttc
    28141 ataggcttct tctaagcggt aataatctgc cagtggaaac ttagagtcaa ttggtaggta
    28201 gacgtattct tggtcgcctt gtccgggtaa cttgatggca tactccactc gttcactaga
    28261 gttttcaacc gttgcgtatt ctcgttcgta ctgggcaggt gtcatgatgt cttcaataat
    28321 ttgccccagt tgcaattctc ccagaatccc tcgcgtcttg gttccagaga gaaccttgtt
    28381 aagagctccg acatcacggg caactgtctg catttctcca agaccacgat tgacagactc
    28441 cagttgttta gaaactgtct caaaggaagc ctgtaagcgt gtctgcaagg tcttttctag
    28501 tttttcctcg accgtctggc gcatttgttc caaacgttgc tcatttgatt cctgcaaggc
    28561 ttggagacgt tggtctgtct tgtctctagt ttggaggaga ttatctgtca tttcttgacg
    28621 gacttgggtc aggccttggt gcaattcaat ccgcacttct tgcaaacggt cgctgacagc
    28681 cacttccaaa tctttttggt ctaactggct ggcttgtctg gcttggtcaa agcggtaatc
    28741 caactggtct gacaaatgat ctgcctgatc ctccaagctc ttacttaagt gtttctcctg
    28801 cctatcctgt ctttgccaaa tcagaaagag accagctagg ttggcaatta ataatagaat
    28861 aagtaaactt tccatcctac ctcctgtcct tgctatgcag tacgaccaca taaccatctg
    28921 ggcaagtcac cgacacttcc ctatctatat attcgttaga agcgtacact tttttaaaga
    28981 aaaaattctc ctctgtcaac tcatacttag ctccaagaat agtcagctgg ctatcccgaa
    29041 ctggcataaa ggctagatag tcgtagtctg aacgaggttc tagctgactg gtcccttctg
    29101 aacaataggc aatcaaattt tgcccatcct caatttctat ttgacgcata tagggtgcca
    29161 acttaggatt gctaggtaga aagacattgg ccaacatatg gtcaatacgg ccacccaagg
    29221 caccgaaaat agtgacctca gcctgaggat tttgttcaaa gatggttaag agagccaatt
    29281 ccagatctgt atcatccttt tctggtcggg cttggacaaa atgctgggca cgtttttgaa
    29341 tcacctgtcg ctcttcttcc gtcacagaat caaaatctcc gactgctaga gcaagaggta
    29401 agtcttcttc caagacccag agcgagcctc gatccacccc aacaaaagca tcaaaatctg
    29461 tccgataatg accgcggttt ccgcctgcaa aaacggcaac cctagtccag ttgttttctg
    29521 agagtttgta ctcgctcatt gacttctccc ttaaagacat aggaacctgc tacaaaaaca
    29581 gtcgcaccag cttctttggc ttgagcaata gtttggtcat caatcccacc atccacttcg
    29641 atttcaaagt tcaaaccttt ttcctcacga agagcaacca actcacgaac cttatccatg
    29701 gtttctggca gaaaggcttg cccaccaaaa cctggattaa ccgtcatgac taaaacttgg
    29761 tcaactagat gaaggacgtg cttgatggct tcaactggtg tgccaggatt gataacgact
    29821 gaaggcttaa ctccgagtaa acgaattttt tggagggcgc catgaatatg aggtgttgct
    29881 tctacatgga tactgatgat gtctgcacct gcacgcgcaa aatcttccag atgatgctca
    29941 gggtttgaca ccatcaagtg gcaatcgaaa accatcttac tatgaggacg aaggctctcg
    30001 accacacctg caccaaaact gatttgcggt acaaaatgac tgtccatgat atcgatatgg
    30061 gcatattctg ccccagttgc ttctagacgt ttgatttcac gttcaaagtt ggcataatct
    30121 gctgccagaa ttgacggagc aatcttgtat tgagacatag gtttctcctt attttggaat
    30181 ttttttgctg acttttttat aggtttctct acgattttca atttcactaa ggaattgcag
    30241 gtaattatca aaacggaagg ttgcaataac accctcttca acagctggtt tgacggcaca
    30301 agacggctca tgggtatggg tacaagtacg gaacttacaa tctcggctaa cagtagcaat
    30361 ctctgggaaa gcctgattga ggtcttcagc ccttgatact tcatagtcca gagatgaaaa
    30421 gcctggtgta tctgcgattt tacccccgtt gagattgtaa aaactaacag ctcgagtggt
    30481 atggcgaccg cgacctagac tgtctgaaat ttctcccgtt tcaagattga ggtctggtac
    30541 gagtttattg agaagagttg acttcccaac acctgtctgc cccataaaga ccgtaacctt
    30601 gcctgttaac aaagacagga gttcctcttt actggtcaca aagtcatagc cgatgtcacc
    30661 ataggtctgc cggtaaaaat ccagttctcc cctatcttcc aacaaatcca ttttggaaat
    30721 atagacaatg ggatggatgc ccttgtgctc caaaagaacc aagaaacgat ccagcaaatt
    30781 gctgttaaaa tcaggttcct tgacggacat gattactaca gcttgatcga tattgacaat
    30841 aggcggacgg accagactgt ttttccgttc gtgaattttg aggatatagc cttctgaatt
    30901 ttcctcggca gagaaatcta cccagtcccc aacataaggg gtatggcctt ttttacggaa
    30961 attcccacgc gcgcgtgttt gataaacctg gccatcactc tccacatagt agaaacctgc
    31021 caaggcttta atgatttgtc cctgcatctt agagtccttg ccctttaagt gcgtctgcta
    31081 gaccggcaaa ttctgccaag ctgagagctt ccccacgcac acttggtgac aagcctgcct
    31141 ggtccaaagc cttggtcagc ttgtccttga cctcttcagt cttaccaaag taacctgtca
    31201 agttattcca caaggtcttg cggcgatggg taaaactagc cttggaaacc ttaaagaaaa
    31261 agttctcatc ttctactgct acggctggct ctggacgacg caccattttc aagatggctg
    31321 aatccacatt tggcgctggc acaaagaccg tacgaggcac gataaaggca accttggctg
    31381 tcatgtaata ctgcacggcg atagacaagc taccgtaagc cttggtgtta ggctgggctg
    31441 aaatgcggtc cgctacttct ttctgcatca tgaccacaaa ctcacaaaaa ggaatgccac
    31501 tctcaatcaa gtgcatgaga ataggcgtcg tgatgtagta aggcaaatta gccactacct
    31561 tgattggcag gttaggattt ttaaaatttt ggatatgttg cgccaaatca accttgagaa
    31621 tatcttcgtt aactacagtc acattatcaa aatcacgcag ggtatctacc aaaattggca
    31681 ccaaacggtg gtcaatctca aaagccatga cttgggctgc acgctcagcc agaaactccg
    31741 tcaaggcacc aatacctggc ccgatttcga tgacattgac ctggtcatca atttcagccg
    31801 tatccacaat tttttgaagg atattggtat ccgtcaggaa attttgcccg aaggactttt
    31861 taaaggtaaa accgtgacgc tccagcactg ccttggtcac gctataatct gcaattctca
    31921 tctattctct tttctattat ctgttactac tattgtaaca cattcccctt gtattttggg
    31981 aatgaaaatc ataccaaaaa actatctttc ctcatgaaga aagatagtct tggaaatctt
    32041 taaaagtggc cttaacagtt ctctcgaaac atgcgttcaa aaaaatcagc ttcttgataa
    32101 cttcgatttt caggtagggt caaatccaca tcctcctcca catcatccac tgtcagttca
    32161 accgtctgag gtaaattttt caaacgataa tgcttttgcc tttgcccttc aatactagca
    32221 aaatcaagca aatagccatg cactcggatt tgaaccaaaa ggagatgatt ggtcatattt
    32281 tccatgatga ggatatcttc taaaccacct ctggcactag gataatcaga taccctgcga
    32341 atacggattt tttcacacat gagcaagttt cctcatatca atgatttcat cagccttatt
    32401 ccagactagg ggattatggg tcgcaatgat gataattcga ttttcatctt tcaaatccac
    32461 caagagattc ataacctcct ctgaattttc aggatcaaga gctgctgttg gttcatctgc
    32521 caaaatcaag ggtggatttt tcaaaatagt cttagcaagg gcaactcgtt gggcctctcc
    32581 cccagataaa gtatagattt tttgttctaa atccaaatac cctagattaa ctttttctaa
    32641 agcccccact tgcctttcca aacgttctac ttttgagatt ttctgaccaa caaaacccaa
    32701 atccaaattt tctttgattg attggttttc taagaggccg aaattttgaa agagatagcc
    32761 catctggtct cgaaaatact cacgagtggg aatggttttt aaatctttcc cctgatagag
    32821 aacccttcca ccatctatct tttctagctt tcccaagata ttcagcagcg tcgtctttcc
    32881 gcttccactc tttccgatta aggcataaac cttgcccttc tccagcttga gattcaaacc
    32941 agagaaaatc gcgcggtcat taaatttctt ttccaatcct tgaatatcaa tcatcttatt
    33001 ttcctttcaa tactgccatg ctaccagctt cttctttttt gtcctgcctt actaaaatca
    33061 agagggcgtt aagcgtaaac aaagctacaa ctagagcgct aatcaaacca tctcttgtca
    33121 aaatactaga taggactaag ccaagcaaga gaactcctcc ttgcgccagt aaatacttgc
    33181 catgaagctc atagattgtc ataccagcaa gacgtttaat cataagctcc cgtctgaact
    33241 gctcaaaata gagaagattc atggaatcaa ataacaagat agccgtagac agggtcaaaa
    33301 tcgtcccaat aaggagagag taaaactcca cccgtttgtc atttagtacc ttggcaaaaa
    33361 atagctggct ttttaccaag taagaaacct tgtgatacag accttgctct tttagagctg
    33421 tgatgctgtc tccatatcga tctagtttca aggcactatt agccgtagtt ccccacaaca
    33481 tccctgcaac aggtcttgtt ccagtcgctt gcggcgttag aactacaata atcggatctt
    33541 ttaggtactg gcgtgttgtc ttgtacccat cattatagag gaaacgttcc tgtcctgttt
    33601 ctgtaaaagc tagccttacc tgtgggaggt agtgtttctg actcgtcact tctacacttt
    33661 cagatgaaaa attttgcagg taatctgtaa acaatccttg gtagtagaca gactgctctc
    33721 gcaagctctc aggcaagatc agcccaaact ctccctcaga caagttttgc atcttgtcca
    33781 taaactctga agaaacggta atcttttctt ctatcagata gcgtggtgag acatagataa
    33841 cattccctga cggtgtgtag tcactgagac gattgccatc taggtccact tctgctccat
    33901 ctgagaaatt gtcaacattg ctcataatat aaaaagagtc tgtattggct aaccgttctt
    33961 cagtaaatgt ctgccactca cgattatcct tacgcgttcc ttcttcatcg gcaaatgcac
    34021 tagaccaacc aaaggataga cggtaacggt ctgaggactg gctccattta ttgctagctc
    34081 tctccatttc ctgcatttca cggtagtggg gtaggagagc tgtcgcactc gatccgacca
    34141 ccaatacagc taagagttgc cccaccatca tcaatgtcat catacgtttg agagggagtt
    34201 tccctttcaa tagatccacc agactatttt cctgtaaacc aagtagatgg acgacactta
    34261 gtaaggtaga aatccctgcc aaggtcaatc catagagtag aagagcaatg atgaccagtt
    34321 gcaccgttgc cataaacaag gcaccttgat accagagaat ccccaatccc aaaagactgg
    34381 ataccagcac tgagcagata agctgtctca catcttctaa cactggtctg agagcaactc
    34441 caaacaagct ctcaccagct attaagcgaa tccctgcttg acgaagggat tttatccgat
    34501 aaatcagggt cagactcata aaggtcagca gaaaaatagc taaactcagt agcaccatag
    34561 gggtggccgt caatagtaag actatcgaaa atggatcttc tccattcgaa acaaagcctt
    34621 gatagccaag ttctttcaag gtggtctgta agctcactcc atccaaactt cctgacacaa
    34681 tcaagtaaga ccctaataaa tcactcgttt ctgcactctc cttggaggaa atggtcagac
    34741 cttctggaag ctctccctca ccataagttg cataggtaaa gcgtgtttct ccagcttcat
    34801 ttggctcaac gattcgacgg gcgatgagac tattatgctc taccgccaag tgactcaaag
    34861 cctctgtcac ctcttcgcga ctagctactg gttgatttgt catcattcct gtcacatcaa
    34921 cagaaggata gttaccaaat aaaatctctt ctcgatggtc aacggaagtt atcaccatat
    34981 aaagcgatac caataccatt gaaatcaaaa taaataaacg tttcatcatt tcctccaaaa
    35041 agttacttgg tcacttagtg agaaggtgac caagtaaagc taaacaatag ggctatacca
    35101 ttctaaacat tatagtagaa tgcaactttc tctccccaag aagtacgaat ccatgcacga
    35161 gaagtccctc cagcaccagc atatcccttg tcagatgaac cagtttttct gctaacaact
    35221 gttgaactat ggtattttga agggtgatag tagtttgagt aagcaccacc gttacctgaa
    35281 ccataagtcc aaacaccacc ttctgggtat tgaacggctg cagaggcaac tgctacactt
    35341 ccacctaatg ttgctgcaat gctcgctaca agagctaatt ttttaactgt ttgtttcata
    35401 ttgatactcc tctatttttg attacaagat tgttgagtta cttgctcctc tttccattat
    35461 caacgttgat actattatat taccaaatga tattctaaaa ttatttgttt ttctctaaat
    35521 tgtcaaaata gcaccctgaa atgaactttt atagtcatta tactccatct ttatcacact
    35581 atcaaggaca tcaatgtcct taaaatctaa ctatttcata ttatttttag cctatatcta
    35641 aaaaaacagt tctaaagacg aactttagaa ctgttttgat acgaggacaa ggacattttt
    35701 gtcactgatt cactatgttt ataaatattt tttgacatcc tcttgccatt cctctgtcaa
    35761 tttctttact agaaattcat ctccaattag ctgcgcaaat gttttagaag actgataaaa
    35821 tgattcagct aaactaaaat ctctttcttc tcttaatgct tgcttccaca aaaacataaa
    35881 tacaagaggt ttcttttgat aatcttgagt tttatccata atttcttgta aacacgatag
    35941 ataatcatta aaacaatcag ttactcctac cttttcaaga caacacattc ctgaaataag
    36001 agtatctcta attataaaga agttttctaa tttagttacc tttttctgtt ccaaaagaaa
    36061 gagcattagc ttttcgattt gatttataaa tttggcaaga tcttttctaa tgagcatttg
    36121 ataaaaaaac aaacgaatca acaacatatc atttgttgaa taaacttctt tttctatgat
    36181 ctgagacata tgttcctcaa gtattaactc tgcatattca ggccttctag ttctagaagt
    36241 atccaaacac gcctgcaata cttcacatgc taattgttct tctttaggaa gattatcaaa
    36301 gtatgtttta taaatctctt ccaaacacgc ttccttctta tcgtactcct cttctttacc
    36361 atagattggt tcacgtaaaa tctggtattt caattctaaa taagcaggag gaagagctga
    36421 aaaatccggc ataaggctat aaactggaac tcctagccgg cgagcaatat aggctaactt
    36481 gggcaaactc ggttgcgaag ctccactttc aattcgcgac agttgacgaa ctgtcagttc
    36541 ttgctcatct ccacaaaaat ctggacgact aactcctttt tctatccgaa tctctttaat
    36601 tttttgacca attaacatca gacgcctcct cttctacctg cttcgaaaaa tactgtgaaa
    36661 cttaaaaaat tgtaacggtc acatctttcc tactcataag atttcatagc ttcttccact
    36721 tctgccaaag taaccccaaa caactctagg cgtttgagga gttgcttgcc gttagaatag
    36781 ccgattcgga gagtctctcc gagatattcc ctacgcttac ggctgtctgc ccctactaga
    36841 aaaccaaggc gaatcaagtc gctacgacta atgtcaaact gactctcatg ttcaaattgt
    36901 tctgtcacct gagctagagc cgttttcagg tcttcatagc tggcatgctc aattcccaga
    36961 gaacgcccct tggtcttgga cttgggaaca gcttcatctc gcttgagaaa ggcatgctga
    37021 actgttggaa tgaccgtcat gatcatgcgc cgaatccgtt ccccattaaa atctgggtct
    37081 gtaaagacaa tgactccatg acgttggtgc aggcgctgaa tccgctctat atcctgatca
    37141 ttgatggcag aacctcgagt ctcataggtc tccacatcga aataacgttt gagattgacc
    37201 gtatcatcac gcccttcaac cacaattact tgggaaattt tctctttcat tacttgctgt
    37261 ccagtccaaa aattcgttct gcatttgcag tcgttgctac cgccagctct tctgtcgtca
    37321 taccacgcaa gtcagcgata aagtcgacca catagcgagt ataggctgtt ttattttcac
    37381 gaccacgctt gggtacaggt gctaagtaag gcgcatctgt ttccaccaac atcttgtcca
    37441 aaggtaactc tttagctgct tcttggaggt cagttgcctt cttaaaagtc accactcctg
    37501 agaaggaaat ggtcatacca agatccacaa acttctctgc ccactcaagc gtccctgaaa
    37561 atgaatgcat gataccacca cgaggaccaa cgccctcact cttgataatc tcataggtat
    37621 cttccagcgc atcacgggta tggacaacaa aaggcaaatc caagtcctta gatagctgaa
    37681 tctgacggcg aaaaacctgc tcctgcacct ctttgggcgc tgtcatccaa tggtaatcta
    37741 agccaatttc acctaaagcc acaaccttgg gatgttttaa cttatccaac aagtaagcct
    37801 caacttcctc tgtataagta ccagcttctg taggatgcca accaatagtc gcatagagct
    37861 gctcatactc atctaccaac tccaaggcac gctcaatcgt cggtttatca aaaccaacaa
    37921 tattcatctg tgtcacaccc atctcagcag ccaaggcaat ttcttctgcc tcacgacctg
    37981 caaattcttc tacattcaag tgtgtatgtg tatcaaaaat catctcttct aacctcgttt
    38041 tctatcttct attataccaa aaaagaggag gggcacctaa tttttcggtt tcccctcctc
    38101 tcttcaatag agagctattc tgctatcttt tctatccgat attgcccatc tcctattcca
    38161 cagttagaga cagaagagat tggctacatt gatagactat tcctattcag ctaaagtatg
    38221 tgattatctt gggttctcac ttttctcacc catcactagg attgatgact tctcaaaatc
    38281 ccccttataa tctaacttta agtagagaat agaattttct agctgttcca ttttctacgt
    38341 ctagtctttc ttcctagcaa agcaaaacca ctggttgccg ccactagacc aagactagca
    38401 agtgctgcac ttgatgctga acctgtgtta ggtaattgtt tgccagcagg tgactggtag
    38461 gtaacatctt gcattgttcc tgcagttgct tgcggtgcac ttgttgtctt aggagcagca
    38521 ttaggagcca ctggtctctt aagaactgta accatggcaa tggcttgcac tccaatcgtt
    38581 tctgcttcct tcacatcttc catagttttc gtattttcaa tctctttgag agctgcttgt
    38641 ttttctgctt ccactcttgc taaaagttct gctttttctt tatcagaaag cggtgcgcct
    38701 ttgatttcat cctgcttgtc cttggctgct ttttcaatgg catttttagc tgattctttt
    38761 tcagtagcta attgcttaga agcttgtgat tgagctgagt tttgtgaacc tgtgtgagct
    38821 ggtccacctg cctggctacc accgcctgca ttcgcattag catctgagct tccagtattg
    38881 cctcccttat ctacacctag tgtagtttct ggcttatact ctggtgtagc ttcttgagtt
    38941 acagattcac ctttcgcaga ttgttgaact gtatcttttc ctagaatcgt cactactgaa
    39001 ccatctggga atgtgattgt tgctgtacca tctccagcta cttcaacttt atagcaaaat
    39061 gaaacaataa caggacaaat cgatcaggac agtcaaatcg atttctaaca atgttttaga
    39121 aacagaggtg tactattcta gtttcaatct actataacat cgcttccgaa tccatttgca
    39181 tctactgaac ttttttacaa aaataaaaat cagtagactc gagttcctac tgatttttga
    39241 tagaattcgt ttggattatg cagccaaaac tttgcgtcct ttacgacgac gagctgccaa
    39301 tacgcgacga ccatttttag ttgacatacg gttacggaat ccgtgtttgc gcgcacgacg
    39361 aagtttactt ggttgataag tacgtttcac gatgaatacc tcctcataga ttttgtattc
    39421 gtttagccgg ctataaagtg atcagttact aaacatactt tactattcta tctgattctt
    39481 tcacttttgt caatagctct aggcaaatgt ttccagcttt ttcgaatgca agccctatct
    39541 acgatactgt ttcaagaaac gagtcatctt ttcttggatt tgggctaact catcaacacg
    39601 aggaaggtaa acgatacgga agtggtctgg ttcctgccag ttaaagcctc gaccatgaac
    39661 caagagaacc ttttcctgct tcaagaaatc aaggacaaac tgctcatcat catcgatacg
    39721 gtacatattg cggtcgattt ttgggaagat atagagcccc gccttgggtt taacggcaga
    39781 caaacctgga atatcttgaa tggcattata gatgaaattt ctttgctcgt agattcgtcc
    39841 accaggaaga agcaattcat cgactgattg gtgacccccc aaggaagttt gtacgacttg
    39901 ttgggccaaa acgttagagc aaaggcgcat attggacagc atattgagcc cttcgatata
    39961 gcccttaaca tgagtcttag ggccagacaa gaccatccaa cccacacgga aacctgctat
    40021 gcggtgggat tttgacagac cattcatgct gacacagaag acatctggtg ccaagctcgc
    40081 cacaggcgta tgcacatgtc cgtccattac catgcggtca tagatttcat ccgcaaagat
    40141 aatcaaatcg ttttgacggg caatctcaat aatctccagc aagagttcct taggataaag
    40201 ggctccagtt gggttatttg gattgataag gacaattgcc ttggtattgg aagtgatttt
    40261 tgacttgata tcgtcaatat ctgggtacca ttccacagct tcatcacaga tatagtgaac
    40321 ggcatttcct ccagctaggc tgacagccgc cgtccataga ggatagtctg gcattggcac
    40381 taagacctca tccccattgt ccaaaagccc ctgcatggac atgacaatca actcactgac
    40441 accatttcca aggtaaatat catcaatatc tacgtttggg aatttcttca gctggcaata
    40501 ctgcatgatg gccttacggg ctgagaaaat ccctttggag tcagaatagc cttcactatc
    40561 acgcgcattc ataatcaagt catgaatgac ctcgtctggc gctgtaaagc caaattctgc
    40621 tggatttcct gtattcagac gtaaaatctt ttctccattc gctcgcatcc gcatggcttc
    40681 ttccaataca ggaccacgga tatcataagc aacatgctct aacttactag acttgttata
    40741 ttctttcatc ttgtttcctc aattcatcag gatagtaaca ttataccact agaaagagaa
    40801 tgcgacaagt ttactgaaat gtgttactag tttcgtatag aagaaaaacc ttgctaaagg
    40861 cgaggttaag aacgtagaga tagcaggtat tttgcaaaga cacatcacat accaaaagat
    40921 aaacctagaa aaagcaagcc tagaaaggag tcataaagaa gattaaacat gaggaaaagc
    40981 ccccatatca tcaagtaatc ccaacgccca cttcgttttg caactagaaa taagattaga
    41041 tggtagagta catgaaaaac taaaaatcca ataaaacttg gataaagaag cggtaccaga
    41101 ctctctaatt gacagatcat gatcacttct accaagactg aaactaggat aattccataa
    41161 taaaggaaat ttgatttttg aaaagagttt ttcatcattc tcccttcctt cacttctttc
    41221 ctgctatcct ttcttttatt ttatcatata tttatataga gtttaagccc taatattctt
    41281 ttgaaaaata ctttttttgc tttacttcta tagtgaaaag gtttacaatt atagtaagaa
    41341 aatttcagga ggtttcatta tggcacaacg ttaccaaaat atcatggtcg caatcgatgg
    41401 ttctaaggaa gcggacttgg cttttgtcaa gggagttcat tctgctctac gaaacgacgc
    41461 taaactcacc atcgcacatg tcattgacac acgcgctctc caaagcgtat ccacctttga
    41521 tgctgaagtt tacgaagaac tccaagtcga cgctgaaagt ctgatgaaag agtacgaaaa
    41581 acgtgctaaa gatgctgggg tagcagatgt tcatatcgtc attgaaatgg gaaatccaaa
    41641 gaccctgcta gcacgtacta ttccagatgc cgaggaagtg gacctcatcc tcgttggcgc
    41701 aactggtctc aacgcctttg aacgcctctt ggtcggctct tcatctgaat acatactccg
    41761 ccatgctaag gtcgatttgc tggttgtgag agaacaagaa aaaaccttat aatcacaaag
    41821 aaaaggagcc cctagctcct ttttgtttac gatttatttc tctctttatg gcgttcgtaa
    41881 gccttgagct ggcgctgcag ttccttttta atagcaggtt ctggagcata tttttcttcc
    41941 caattatctg gttttaagat tttatgggtc actggatcaa aatgagcctt gccatctgga
    42001 aaaattttcc ccatattggc ctgatggaca atatcaaaaa tacgttctgg gtccaccccc
    42061 atcaagacaa aactgccgta ggtgaagtaa agcgtgtcaa tcaaggcatc cacttgccct
    42121 atcaaatctt gctgagcagg tgtcttcttg gctactttat ctgctgcctt atcaagggcc
    42181 tgatgaagtt gcgatacagc ttgaccaaaa tcttcttcag aaggactggc tgctcgaaca
    42241 aactccacca attcttctat tttaaaacca gccctatggg ttgcaccctc taaatcccaa
    42301 gctcgaggtt cttcttgggt tcgttcatcc atcatgtggt ggaaggtctt gaccttattg
    42361 aaatgatagt cacggctgac aaagactttt tctgaagaca aaacaccaaa atgttccaag
    42421 gccttgtgga tcccatcttg ttgattgcta gtggtaatgt gcttggcagc ttccttgaca
    42481 ctgctactac catttcccat agcgaccgac ataccgacgc cagccagcat ttcaaggtca
    42541 ttatctgagt caccaaaagc catgacttga ttgaggtcaa agccatattc tttcccaact
    42601 cggcgaatgc cttctaattt agaatttccc tgattgatga catccgatgc aaaaggattg
    42661 ctacgtgtca atttcaagtc ttcaaaatca gctgccgcct tctcagattc ttctggtgtc
    42721 atcagcatca aaacttggta gataggctga ttcatcaggt gaagcaggtc ctcttccttt
    42781 tggggaacaa ccttgctgac catgcgatta aaagactgac tcaccgtccg agttaaaaca
    42841 gagggaacga agcgactaat tcgttgggaa aaagaaccca gaccaaagga catgatttta
    42901 gaacccaaca tggcatcctt ggtccctagg gcaatctccg tgccctcttt tttagcatag
    42961 ctaattagat ggcgcaaatg taacttggaa atagggctcg tgaacaagac tctgtcttta
    43021 ctaaagatat actggccatt ataggttacc gcaaaatcca gatccaaatc gtccatcaat
    43081 tccttaacaa aaaaaggtcc tcgccctgtc gctacgccaa ctagtacccc ttgttctttg
    43141 acaatcttaa tcgcatcctt agtggatttc aaaacactct tgcgattgtt gaccaaggtt
    43201 ccatcgatat caaaaaaaac agctttgact tccatcctat cccaatctcc ccttttgtga
    43261 tacaatgatt ataccacatt tcagaaagag ttagtaaatc atgcctaaga aaatccttgt
    43321 tttacatacg ggtggaacta tttccatgca ggccgatgct tctggcgctg ttgtgacgag
    43381 ttcagataat cccatgaacc atgtgtccaa cccacttgaa ggaatccaag tccacgcctt
    43441 ggactttttt aaccttccaa gtccccatat caaacccaaa catatgctgg tcctctacca
    43501 gaaaattaaa gaggaagcag ataactacga tggagtggtg atcacacacg gaaccgatac
    43561 tttagaggaa acagcctatt tccttgatac catggaagtt ccccatatgc ctatcgttct
    43621 aacaggagcc atgcgtagct ccaatgagct cggtagtgat ggtgtttata attacctaag
    43681 tgctttacga gtggccagtg atgacagggc tgctgacaaa ggagttttgg tcgttatgaa
    43741 cgatgaaatc cacgctgcca agtatgtcac caaaacacat acgactaatg tcaacacctt
    43801 ccagactcca acacatggcc ccctcggtct catcatgaaa caggaaatcc tctacttcaa
    43861 aacagctgaa cctcgtgttc gctttgacct tgatcacata caaggtttag tccctatcat
    43921 ctcggcttat gctggtatga cagatgagct gattgatatg ctggatttag aacacttgga
    43981 cggtttgatt atccaagcct tcggagctgg taatattccc aaagaaacgg ctcaaaaatt
    44041 agaaagcctt ctgcaaaaag gaatcccagt cgctctggta tcacgatgct ttaacggtat
    44101 tgccgagcct gtttatgcct accagggtgg gggcgtacag ttgcaaaaag caggcgtttt
    44161 ctttgttaaa gaactcaacg cccaaaaagc ccgcttgaaa ctcctcatcg ccctcaatgc
    44221 cggactaaca ggacaggctt tgaaagacta tatggaaggc taatactctt cgaaaatctc
    44281 tgcaaaccac gtcacgtcgc cttaccgtat gtatggttac tgacttcgtc agttctatct
    44341 acaacctcaa aacagtgtgt tgcgcagcct ttaaccagcc gcctagtccg ctctatggta
    44401 ttcattaagt caacatctct tgtttaagag cacaaaatca ggaaatcttc tcgattccct
    44461 gattttttct atttacgttt tcgtgttgag ctacgttctg tcaaaccatg aggtaagaga
    44521 acttcacgtt cttccaactc ttccttatgc ataatcttgg tcaacatacg catactaatg
    44581 gcaccaaggt cataaagagg ttgggcaatc gttgtcaagt ttggacgggt aaagcgtgag
    44641 atttgtgaat catcactagt aataatttca aaatcttctg gcacagaaac acccttatca
    44701 gccaaaccgt tcaagactcc tgctgccaac tcatcacctg tcacaactgc tgcagttgca
    44761 tttgatgaaa tcaaacgctc tgctaaggcg taaccatcat catagctata tttagattca
    44821 aataccaaac cctcactata agcgattcct gcttttttca aggtttcctt gtagccaact
    44881 aaacgaacct taccattgat gtcatccact agcggaccgc taacgaaagc aatacgctca
    44941 ttttctttag caaggtaact cactgcatca attgttgctt gcttatagtc aatattgaca
    45001 cttggcaact ggtgctcaac atcgacagtt cctgcgagaa caatcggagt acgtgaacgc
    45061 gaaaattctg agcgaatttt atctgtcaag tgataaccca tatagataat gccatctacc
    45121 tgctttgaaa agagggtatt gacaacagaa acttctttct cgttatcttc atcgctatta
    45181 gctaggacaa tattgtactt gtacatttct gcaatatcat caatcccctt agccaaactc
    45241 gaaaaataac cattggtaat atttggaatc acgacaccga cagtggttgt ctttttactt
    45301 gcaagaccac gcgcaactgc atttggacga taatccaagc gatcaattac ctctagcact
    45361 tttttacggg tattctcttt tacattttta ttgccattga ccacacggct gaccgtcgcc
    45421 atggaaacac ctgcttcacg agcgacatca taaatggtta ctgtatcatc tgcattcatt
    45481 ccttttcctg tcctttctat ctcacacatt cttttacaag tagaggtact gattgaagct
    45541 ctatatctac ttacaaaagt gaagatgtga aaatttcgtt ttcatatttc tacttattcc
    45601 attctatcac taattgtaaa cactttcaag tgttttttga agattgattg aaaaaatttc
    45661 atagaaaacc taggtttagc tccttgctac caccttagac taaacaaaaa ggaggaaact
    45721 aagccctcct aaagttatag taaaatgaaa taagaacagg ataaatcgat caggacagtc
    45781 aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt caatctacta
    45841 taggtattgt tccattcact accgtcaatt ttagcacata gtcttcatga aaatattata
    45901 tcatcataac caaccagatt cttttgcgat attagctgcc tctgttcgat taccagcatc
    45961 caattttgaa agaatattgg tgacatagtt tcgaatagtt ccgtttgaga ggtaaagctg
    46021 atctgcgatt tcttggttgg ataagccccg ggcgatcccc tttaagacag caatctcttg
    46081 ttctgtcaac ggattgggac gggtcatcac cacttccatc aattcaggcg aatactcctt
    46141 gcgtccttcg aggacggtgt gcaaggtttg catgaggtct gcaacgcttc gttcctttaa
    46201 tacataagca tccactccag ccttgaccgc acgttcaaaa tacccagcac gcttgaaggt
    46261 cgtcaccaca accacctttg tttcaagcct ttctgatcgt atccactcca agacttcaag
    46321 acctgtctta acaggcattt ctacgtcaag gatggcgata tctacagact ccttttctaa
    46381 tagttggatt gcttcttgcc cattcttggc ttgaaggaca gactccacat ctggttgaag
    46441 cgtgagcaat tgacacatgg catctcgcaa catactttga tcttctgcga ctaatacttt
    46501 catcttagtt tctctcctta taaggtagtc gaacttgcac ttccgttgga tgtttctgac
    46561 tgattacact tacttctcct gaaaatggaa aaacacgatc tcggattgta tggagctcat
    46621 ctccttttag aaaagcaaag ccgcagccat catcacttac tgttaaaatg agttccttct
    46681 ctgtccgttc taattttaag taagctttag acgctttggc atgtttgatg atattggtca
    46741 ccaactcaag caaaatcata gaagccattg actccaattc ttgagtaagg ctagcagtat
    46801 ctagttggtt atccgtttcc acctcaattc cagcaatttc taacatcttt ttcacagtct
    46861 ctagttcgga tgtcaaagtt ctagacttaa gattttccac aatggttcga acttcacgca
    46921 ttgattcttt gctaatttgc tgtatttctc ttaattcctt ttccacttgt ggataagcct
    46981 gcatttgaaa tagctgcaag gctagatctg tcttgacact aagcatagca aaggtatgtc
    47041 ccagactatc atgcaaatcc tgaccgatac gattgcgctc attttctgct agcaatagat
    47101 ttatctgggt attttgcttg acctgagctt ctttcaaatc ctcgacaagg cgaattcgaa
    47161 ccgagcccaa agtcatcaaa tcgacaaaag taagaattac aagcatatag actagaaact
    47221 caacttcgat tctctgaaaa atcaaaagtc gccccacaac aaggacttga gcaaggagaa
    47281 atgtccatac atgtaaagac tttaaactac gtacgccaaa atgataaatt aagagattgg
    47341 aaaggaaaaa gaaaaaccag atataattcc cagcaacaaa ggcggtattc ccagctacat
    47401 agaccagcat gatcccccag aaaagccatg atatgcgctg gttcttagtt attaaaacac
    47461 ccaaatacgt cactacaaat agaatatcaa ccaataaatg ccaagcagga agctccccag
    47521 tcactacagg taggatgggg aaaatcataa aaattaaact tgcccaaaac atatagtgta
    47581 tgcttttcag tctttcaagc attaagcatt ctccttatga ccttgaaggt aaatggtcaa
    47641 accaaacaaa actgctgaaa aaacaagtag ataaactgtg gctgatagat tgatgccacc
    47701 ctcgtttaag aaggtcttga gcaactccat caattgatag gtcgggagac acttaccaac
    47761 tgcttgcatc cagtctggaa ataaagaaat gggcatccag agtccgccta aaacagccaa
    47821 tcctagataa agaagattgc ccacaacaga catcagctga ctagttggta agagagtcaa
    47881 ggtcaagcca agtgctacaa aagcaatact ccccacaatc agcaaaatcg cagctccaac
    47941 ccattttact agaggcatgt ctacacctct tacaaaatgt ccaactgtaa aaacaaccag
    48001 aattgagacc aaataatcaa ccagcatact tgttatcttt gatagataat attctaccat
    48061 atttacaggg ctatgacgca atgttttctg ccagttgttc atcttatcgg tatgtaaaac
    48121 agctggaaat gagaggatag ttgtcgacat catggaaaag gcagtcatgg agatgaggta
    48181 atcacgcata aaattcgcga gttcacctgg tgtgtcctga tagataccag aaaaaaataa
    48241 atagaaagcc gtcggcatcc ctaccgacaa tagataatag attaattgtc gtttggtcaa
    48301 taaaaattct atcttactaa gtgctatcca tcgtttcatc ttagttatct cccttctgcg
    48361 tctcttcaaa gattgtattc aacaaactac gattattaac ttcgatttct tgcatcctac
    48421 atcctgcttg ggctaatagt tcccagaaag catctgcttc tcgagtgact acttgtaaag
    48481 aatcttgctt tagggtccag ttttcaacca aatttgactg ctctacgact tccttgtaag
    48541 ctataggaag gataaagtgc ttttctattt cctcgctacg catagctaga ggcgtcgtat
    48601 ctcgaatcaa ctctccctta tttaagagca aaatgcggtc tgcagtgtgt tccacttcct
    48661 caatataatg ggacgaatag agaatggtga ctccttgcgc ttttaactcc tggacaattt
    48721 cccaaaaacg ttgacgagtt gaggtatcca tggacgcagt aggctcatct aaaaaaacaa
    48781 tctttggtcg cccaattaag gtcaagacga aagaaaagag acgcttttga ccgcctgata
    48841 atttttctgc caactgttct ttttgttgct tgacaaactg caatagttga tcaatttcct
    48901 gattgctcaa aggatttgga tagatacgtt gaaagaaagc aatcaactct ttaactttta
    48961 atttctgaac gattacattt tcttgaggga ggtaagccct agtatagtct aacttagaac
    49021 tcgtcactgg taaaccttga atagatactt gaccgcttgt gaccagttta tctccaagca
    49081 aacaatctaa gagtgttgtc tttccggcac catttggacc aattaaggca acacattcac
    49141 catcgttgat ttcaaaggag atattccgca aaatttcctt gtcttttatt ttcttactca
    49201 atttctcaac tttaaccacc gtcatgagac tctcctttca accactccat tcccataagg
    49261 aaaacgacga aaatcataaa tccaaacccc aaagcaccac gaatgaattg gcgaagcaag
    49321 gcttgatcaa accaatcagt aaacatttcc actaaccata ccaagagtga caggccgata
    49381 aagaaataga tgatccctct cttcattcct caaactcctt tttcacatct ctgactaatt
    49441 tcaaaccttc tctaacaagc caagacatga ttccaaagcc agcaaagacc ttccaaggaa
    49501 aatggtagaa atcctcatcc aatcccgaaa acatgagata ggtcataact cctgctacta
    49561 ctaaacttac tgcgataatc attttatttc tcatctcttc ttcccccatt tcatactaca
    49621 attatagtct tttaaaatca gaggagacag aagcttctgt cactaaaaaa tatgacaaat
    49681 gtcataaaaa attctgttca aaacaagcaa gatacactat acaataaaac acaatcagaa
    49741 aaatctaagg caacttcctc aaaagagata tcaaacccaa ttcacaccat aatgtaaact
    49801 aatacttatt taaaatcaaa aagagtaaaa atttttatca g
//
LOCUS       DAVLMQ010000009        49507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000009 DAVLMQ010000000
VERSION     DAVLMQ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.009"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..1237)
                     /gene="pcpA"
                     /locus_tag="VXF95_000662"
     CDS             complement(<1..1237)
                     /gene="pcpA"
                     /locus_tag="VXF95_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein PcpA"
                     /protein_id="HEV1081248.1"
                     /translation="MKKTTILSLTTAAVILAAYVPNEPILADTPSSEVIKETKVGSII
                     QQNNIKYKVLTVEGNIGTVQVGNGVTPVEFEAGQDGKPFTIPTKITVGDKVFTVTEVA
                     SQAFSYYPDETGRIVYYPSSITIPSSIKKIQKKGFHGSKAKTIIFDKGSQLEKIEDRA
                     FDFSELEEIELPASLEYIGTSAFSFSQKLKKLTFSSSSKLELISHEAFANLSNLEKLT
                     LPKSVKTLGSNLFRLTTSLKHVDVEEGNESFASVDGVLFSKDKTQLIYYPSQKNDESY
                     KTPKETKELASYSFNKNSYLKKLELNEGLEKIGTFAFADAIKLEEISLPNSLETIERL
                     AFYGNLELKELILPDNVKNFGKHVMNGLPKLKSLTIGNNINSLPSFFLSGVLDSLKEI
                     HIKNKSTEFSVKKDTFAIPE"
     gene            1506..1688
                     /locus_tag="VXF95_000663"
     CDS             1506..1688
                     /locus_tag="VXF95_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1081249.1"
                     /translation="MDLKFEGVDLEYKKAKNNLPESFWETYSAFANTNGGKIILGIDE
                     KNIDTYQRVNRLPAKL"
     gene            1633..2482
                     /locus_tag="VXF95_000664"
                     /pseudo
     CDS             1633..2482
                     /locus_tag="VXF95_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            complement(2534..2896)
                     /locus_tag="VXF95_000665"
     CDS             complement(2534..2896)
                     /locus_tag="VXF95_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081250.1"
                     /translation="MPKTKTLAELADVILWSFDFANDHAHAFFMDNIEWSHADSYFLS
                     FVSDDVEERYTENVYLDSLSVKQKFKFIFDFGDEWRFECQVLREIETEDEEAYLVRSV
                     GTSPEQYPDYDGFDYEEW"
     gene            complement(3187..5067)
                     /locus_tag="VXF95_000666"
     CDS             complement(3187..5067)
                     /locus_tag="VXF95_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1081251.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIQGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRHDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASTIY
                     TT"
     gene            complement(5061..5930)
                     /locus_tag="VXF95_000667"
     CDS             complement(5061..5930)
                     /locus_tag="VXF95_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1081252.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILDKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIRGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAGKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNCNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQGVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(6013..8658)
                     /locus_tag="VXF95_000668"
     CDS             complement(6013..8658)
                     /locus_tag="VXF95_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HEV1081253.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGRPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAYRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVLRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGLLAPQEIRTEFIKKEEI"
     gene            complement(8749..10029)
                     /locus_tag="VXF95_000669"
     CDS             complement(8749..10029)
                     /locus_tag="VXF95_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HEV1081254.1"
                     /translation="MIYSKEIVREWLDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETGQFDETF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADTKRLQDEIQEGIENYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            10200..12284
                     /locus_tag="VXF95_000670"
     CDS             10200..12284
                     /locus_tag="VXF95_000670"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HEV1081255.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QDGAWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDRDK
                     ASFQPHYLKIFSLRYQIETQLTPTCYGASIRLKQKQGKALSLYLHATDELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGQAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDVAPDLEGKLFQAMLETASKADP
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLDKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(12324..14003)
                     /locus_tag="VXF95_000671"
     CDS             complement(12324..14003)
                     /locus_tag="VXF95_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HEV1081256.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIHWIGNERGH
                     AGDPLWQKMNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWASDADLPIQLELDLGSPKTFDVIELREDLKLGQRIA
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGPLVEAQKVRVMITEAQSIPVLTKISLCKT
                     PGLSKKEVVQELAFAEKSLAVAKGETLHFRIERSESSSSLEAKISIQPGTGVHGVAYQ
                     DEIQVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            14758..15987
                     /gene="arcA"
                     /locus_tag="VXF95_000672"
     CDS             14758..15987
                     /gene="arcA"
                     /locus_tag="VXF95_000672"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HEV1081257.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            16048..17061
                     /gene="argF"
                     /locus_tag="VXF95_000673"
     CDS             16048..17061
                     /gene="argF"
                     /locus_tag="VXF95_000673"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000195397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HEV1081258.1"
                     /translation="MNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYL
                     AGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMF
                     DGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVY
                     CGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDA
                     DEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAF
                     HDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYI
                     PKV"
     gene            17226..18173
                     /gene="arcC"
                     /locus_tag="VXF95_000674"
     CDS             17226..18173
                     /gene="arcC"
                     /locus_tag="VXF95_000674"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HEV1081259.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNNGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIILTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            18384..19895
                     /locus_tag="VXF95_000675"
     CDS             18384..19895
                     /locus_tag="VXF95_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HEV1081260.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYEA
                     HPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            19917..21248
                     /locus_tag="VXF95_000676"
     CDS             19917..21248
                     /locus_tag="VXF95_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HEV1081261.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQASMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQTTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEIRIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            complement(21654..21944)
                     /locus_tag="VXF95_000677"
     CDS             complement(21654..21944)
                     /locus_tag="VXF95_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081262.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQINERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(21932..22184)
                     /locus_tag="VXF95_000678"
                     /pseudo
     CDS             complement(21932..22184)
                     /locus_tag="VXF95_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            22388..22465
                     /locus_tag="VXF95_000679"
                     /pseudo
     CDS             22388..22465
                     /locus_tag="VXF95_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(22583..23467)
                     /locus_tag="VXF95_000680"
     CDS             complement(22583..23467)
                     /locus_tag="VXF95_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1081263.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(23611..24762)
                     /locus_tag="VXF95_000681"
     CDS             complement(23611..24762)
                     /locus_tag="VXF95_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HEV1081264.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKVLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMVTNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPQALTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVANGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(24908..26674)
                     /locus_tag="VXF95_000682"
     CDS             complement(24908..26674)
                     /locus_tag="VXF95_000682"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HEV1081265.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHAQKGIPAFGIYGRDVQEASDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERAMVWVKEHIKEGVDRNREDLILSKEEKEKQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVKRVTGHTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELEESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(26731..29847)
                     /locus_tag="VXF95_000683"
     CDS             complement(26731..29847)
                     /locus_tag="VXF95_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1081266.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(29857..32151)
                     /locus_tag="VXF95_000684"
     CDS             complement(29857..32151)
                     /locus_tag="VXF95_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HEV1081267.1"
                     /translation="MKLWYKKAASNWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKDCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPVNLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(32210..33010)
                     /locus_tag="VXF95_000685"
     CDS             complement(32210..33010)
                     /locus_tag="VXF95_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1081268.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(33007..33780)
                     /locus_tag="VXF95_000686"
     CDS             complement(33007..33780)
                     /locus_tag="VXF95_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1081269.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(33805..34275)
                     /locus_tag="VXF95_000687"
     CDS             complement(33805..34275)
                     /locus_tag="VXF95_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1081270.1"
                     /translation="MPIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(34266..34697)
                     /locus_tag="VXF95_000688"
     CDS             complement(34266..34697)
                     /locus_tag="VXF95_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081271.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(34690..35130)
                     /locus_tag="VXF95_000689"
     CDS             complement(34690..35130)
                     /locus_tag="VXF95_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HEV1081272.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(35142..35780)
                     /locus_tag="VXF95_000690"
     CDS             complement(35142..35780)
                     /locus_tag="VXF95_000690"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HEV1081273.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(35895..37298)
                     /locus_tag="VXF95_000691"
     CDS             complement(35895..37298)
                     /locus_tag="VXF95_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HEV1081274.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDVDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLSQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSTLLPEIVSEGNVLGRIKEE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPILTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLVYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEGTAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            37474..38247
                     /locus_tag="VXF95_000692"
     CDS             37474..38247
                     /locus_tag="VXF95_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1081275.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCIYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTLPDQKLLDAVELFDGEWVSDIQ"
     gene            complement(39374..40879)
                     /gene="adcA"
                     /locus_tag="VXF95_000693"
     CDS             complement(39374..40879)
                     /gene="adcA"
                     /locus_tag="VXF95_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HEV1081276.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGEEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISIMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNIAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
     gene            complement(40889..41695)
                     /locus_tag="VXF95_000694"
     CDS             complement(40889..41695)
                     /locus_tag="VXF95_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HEV1081277.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            complement(41688..42392)
                     /locus_tag="VXF95_000695"
     CDS             complement(41688..42392)
                     /locus_tag="VXF95_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HEV1081278.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYSVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            complement(42392..42832)
                     /gene="adcR"
                     /locus_tag="VXF95_000696"
     CDS             complement(42392..42832)
                     /gene="adcR"
                     /locus_tag="VXF95_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HEV1081279.1"
                     /translation="MRQLAKDINAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            complement(42987..44255)
                     /gene="dltD"
                     /locus_tag="VXF95_000697"
     CDS             complement(42987..44255)
                     /gene="dltD"
                     /locus_tag="VXF95_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HEV1081280.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            complement(44248..44487)
                     /gene="dltC"
                     /locus_tag="VXF95_000698"
     CDS             complement(44248..44487)
                     /gene="dltC"
                     /locus_tag="VXF95_000698"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HEV1081281.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            complement(44501..45745)
                     /gene="dltB"
                     /locus_tag="VXF95_000699"
     CDS             complement(44501..45745)
                     /gene="dltB"
                     /locus_tag="VXF95_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HEV1081282.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIIIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            complement(45742..47292)
                     /gene="dltA"
                     /locus_tag="VXF95_000700"
     CDS             complement(45742..47292)
                     /gene="dltA"
                     /locus_tag="VXF95_000700"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HEV1081283.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMSGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMKNPEKTAEAFFEFEGLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            complement(47313..47444)
                     /locus_tag="VXF95_000701"
     CDS             complement(47313..47444)
                     /locus_tag="VXF95_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HEV1081284.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            complement(47758..48936)
                     /locus_tag="VXF95_000702"
     CDS             complement(47758..48936)
                     /locus_tag="VXF95_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1081285.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
BASE COUNT        14852 a        10673 c         8893 g        15089 t
ORIGIN      
        1 tttcaggaat tgcaaatgta tcttttttca cagaaaactc tgtactttta ttcttaatat
       61 gaatttcctt taatgaatct aagacgccac ttaggaagaa ggacggcaat gagttgatat
      121 tattaccaat tgttaaactt tttaattttg gtaaaccgtt cataacgtgt ttaccaaaat
      181 ttttaacatt atctggtaat ataagttctt ttaattctaa attaccgtaa aaggctaaac
      241 gttcaatagt ttctaaacta tttggtaagc taatttcttc aagtttaatc gcatccgcaa
      301 atgcaaaagt accgattttt tctaaacctt cattcaattc gagttttttc aagtaagaat
      361 ttttattaaa cgaatatgat gcaagttctt ttgtctcttt aggcgtttta taactttcgt
      421 catttttttg acttggataa taaattaatt gagttttatc ttttgaaaac aaaacaccat
      481 caactgaggc aaacgattca tttccttctt caacatcaac atgttttaag ctagtagtga
      541 gtctaaatag attacttcct aatgttttaa ccgattttgg taatgttagt ttctctaaat
      601 ttgataaatt agcaaaagcc tcatgtgata ttaattctaa ttttgaactt gaggaaaagg
      661 ttagcttttt caatttttga ctaaaagaaa atgcacttgt tccaatatat tctagagatg
      721 caggcaattc aatctcttct aattcagaaa aatcaaaagc tctatcttca attttctcca
      781 gctgactgcc tttgtcaaaa ataatagttt tagctttact tccatggaag cctttttttt
      841 gtattttttt tatgcttgat gggatagtaa tagagctagg atagtagaca attctacctg
      901 tttcatctgg ataataacta aaagcttgac tagctacttc agtaacggta aatactttat
      961 cacctactgt gatttttgta ggaatcgtga atggttttcc atcttgacca gcttcaaact
     1021 ctacaggagt aactccatta cccacttgaa cagttcctat gttaccttct acagttagaa
     1081 ccttatattt gatattattt tgttgaataa tacttccaac tttagtctct ttgattactt
     1141 ccgaactagg agtatctgct aggattggtt cattagggac atatgctgct aaaataaccg
     1201 cagctgtagt taatgataat attgtagttt ttttcattta aatttcctta catatttatt
     1261 ttctaataga tataaaatta taactttgct agccgttgtt ataaaaagtt ttattcaatc
     1321 attatctagt agaatagagt agtacatttt ataaattgtc atctctccat aaacacagta
     1381 tatcattttt aaattttaag tcaaggaaaa ttaactgagt aaaaactctc gaaattcaat
     1441 tcgctatatt atcactcaac ttgaacaaat accagaacca caaaaaacag atgtaaagga
     1501 aaaatatgga cttaaaattt gaaggggttg atttagaata caaaaaagct aaaaacaatc
     1561 ttccagagtc tttctgggaa acctactcag catttgcaaa tacaaatggc gggaaaataa
     1621 ttctcgggat agatgaaaaa aacattgaca cctaccaaag agtcaataga ctccctgcga
     1681 aattatgaag caagtaaaca attaactgat acacgattta agcgtcttgt tggtgttcag
     1741 cgcacgactt ttaaagagat gttagctgta ttaaaaacag cttatcaact taaacacgca
     1801 aaaggtggac gaaaacctaa attaagccta gaagaccttc ttatggccac tcttcaatat
     1861 gtgtgagaat accgcactta tgaagaaatt gcggctgatt ttggtatcca cgaaagcaac
     1921 ttaatccgtc ggagccaatg ggttgaagta actcttgttc aaagtggtgt tacgatttca
     1981 agaactcctc tcagctctga ggacacggta atgattgatg cgacggaagt acaaatcaat
     2041 cgccctaaaa aaacaattag cgaatcattc tggtaaaaag aaatttcacg ctatgaaggc
     2101 tcaagcgatt gtcacaagtc aagggagaat tgtttctttg gatatcactg tgaactattg
     2161 tcatgatatg aagttgttca aaatgagttg cagaaatatc agacaagttg gtaaaatctt
     2221 ggctgacagt ggttatcaag ggctcatgaa gatatgtcct caagcacaaa cttcacgtaa
     2281 atccagcaaa ctcaagccac taacagctga agataaagcc tataaccatg cgctatccaa
     2341 ggagagaagc aaggttgaga acatctttgc caaagtaaaa acgtttaaaa tgttttcaac
     2401 aacctatcga aatcatcgta aacgcttcgg attacgaatg aatttgattg ctggtattat
     2461 caatcatgaa ctaggattct agttttgcag gaagtctatt gaaatactaa gcctacacag
     2521 actgatttca attttaccat tcttcatagt caaaaccatc ataatctgga tattgttctg
     2581 gcgacgttcc aaccgaacgt acgagataag cttcttcgtc ctctgtctcg atttctctca
     2641 gcacttggca ttcaaaacgc cattcatcac cgaagtcgaa aataaactta aatttttgtt
     2701 tgacacttag gctatccaga tagacatttt ctgtgtaacg ttcttcaaca tcgtcactaa
     2761 caaagctaag aaagtaagaa tctgcatgac tccactcaat attatccatg aaaaatgcgt
     2821 gagcatgatc atttgcaaaa tcaaaactcc ataaaatcac atctgctagt tccgctaacg
     2881 tttttgtttt tggaatctat atatgtcggt agcaaccttt tttaaatttg acggaaatga
     2941 tccaagcctc tacagatgct ggcttttcag cttctatttc ttgttttact aattttaact
     3001 gtagcatttg aaaccagata attcttctgt ttcacgcgaa acaccctgcg ccaagcaagg
     3061 tgttcttgtt tttatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
     3121 gctcaaaaca ctgttttgag gttgtagatg gaagctgacg tggtttgaag agattttcga
     3181 agagtattaa gtcgtataaa tcgtcgaagc tgtcgcaatg gtatgccact ggttagctgt
     3241 agttgctgcg aaatccttgt ctgcgtagaa gtcagtaaat ggtaggattt caacttccag
     3301 ctcgtcgatg cggtcaagct ggccagccag ataaacctcg atacggcttt ctgctcgttt
     3361 gatgcgttgc aagagtccgc ccatacggat gtcaactgta tccaaaccaa agaccttgtt
     3421 ttctttcagc cattggtgac taaagagggc atggaagtct tcaatttggc ttctaagttc
     3481 tggtaattct tgtctggcga tttgttgtaa actttcttta tcatccgctt ggtaggcctg
     3541 acgaatgcgt cgtcccacat ctactttgct acttaaaata gcattcaact gggcctgagt
     3601 ttcaaagaga taagcatagt ttccagcttt ttctttaatg ttagcaagcg tctcagcagc
     3661 ctgagcgaag tgcggtttgt cctgttcagg tgtcatgtgt cggtcaagta tcggacaaag
     3721 aacatcctga taaaagacat atcggttggg attgatgcca ctgagattgc ctggtaggtc
     3781 tggtaagagg ttggcaaggt caatctgcat aaaatcctca accgttagac cagtattggt
     3841 cttgaagtgc gcagacaaac tatctaggtc atggcgatag ctgagttctg cccagatttg
     3901 caagcttggt aggatagaga actgggcagt ttcaccccca ttgtctcccc aacccgttac
     3961 gatgacttct ttaatctgat tggcacggca ggctttatta gcctcgatag ccactagacg
     4021 gctaaaatgg ttgtgaggtg taaagccaat ccacttccaa gctccccctg caaatgcaag
     4081 gtcatggcta atcttgtgat gattgcggaa attacggttg tatttttcct cgctatcctg
     4141 ataataatcc cagtaaacca gagtcacacg gtctttgaga cggtctaggt agacacgagt
     4201 ttcctctgga atttccacat cacggtcgta ctggccatcc gctgacatga gtttgaagaa
     4261 catatcactc cacatctggc agtggaaacc atatttgtca gcaatatcca gcacgcgctc
     4321 caagtgttgg cacatgagga gactacgatc cacaacaccg ttcaaaatca ggtagcgtcc
     4381 caaaccaacc aagtgggctt cgtccatccc gatattgacc ttgcgagtct tcagtttaga
     4441 caacgtggca aacatgccat caatcaggtc ataaaccttt tcttcgccaa tgagaagaat
     4501 gtcctctaca tcacggagct cctgcacttc cttgacaccc catttgacaa aggccgacaa
     4561 gtgggccaag gtctggatgc atggtacaaa ggtcatgtca aactgttgag cataggcttc
     4621 gatttcctgc aactcctctg ctgaataagc tccacggaaa tagccaaagt aaggctgtcc
     4681 ttcaatctgg taagtgtctt ccatgtaaag ctcaaaggtt gagtagccca tgagagccaa
     4741 gacctcaatc atctgcttgg cagaagccac attcagcacc gcatttcgag aacagtcaac
     4801 catgtaagcc aaatcttcgt aagctgcttg ttcctcaatc tctactttat cagcttctgc
     4861 tagaactgtt accaacaagg ataaggcacg ataaagttgg tgaggtttgc ggtaggtcaa
     4921 ttgatagtga ccttcctcac cctggataga gatagaggct tggtcagact gagtgacagc
     4981 cacttccaca tctggtagag aaatgtgacc ttttaaaacc tcaatagctt gcgtttgttt
     5041 gggactaagt cctgtaaatc ttaccattgc ttttcctcct gtagccagtt gacaagggca
     5101 ccgtagagat ttgcatctgc gtgataggtg caggcctgga taactggggc gaccgtgtat
     5161 tcttcgtagg tatcgacaaa gttatcaaca gccttcttga caccttggat aaaatctgga
     5221 ttttgactga tagagccacc cagactgatg acatctggat cgatcagata ctggatattg
     5281 agcaagcctt gcgccagatt gcagttcatg cgctcaatgg cttcttgaca aagagcatta
     5341 ccagctgcgg cctcttggta aatcttgcga ccgtcccaat cagtatgacc agatttttca
     5401 attacgtatc gtaccatatt cccagttgat gctagttgcg accagttatt aagttttcca
     5461 gcaggggcaa gggttgtcat gtagccaaat tctccaccca gaccgtggcg acctcgatga
     5521 agtctaccat tgataatcat ggctccgcca atccctgtcc caatcacgac acaggctgca
     5581 ttttcaagct ctggatgagc tagtagttca ctgagtccaa cgcagttggc atcattttct
     5641 aaatggacag gtagctgata agagctaaga gcctcatacc aagaaaagcc acggatgtag
     5701 ggcaccgcac tgaagccatc aatcacacct gtctcttgat tgactgcacc tggaacgctc
     5761 atagcaatcc cactgtaatc ctgttctgac aagcgttgat ctagccacgc tagtaaatcc
     5821 tccaagtttt caggcgttga aatacttgtc ttatccagta ttttcccatc aggagtcaga
     5881 ctggcaaact taatcccagt ccctccgata tcaatcgttg caatggtcat tgtttttacc
     5941 ataaaagagg cgaatcagca gttagttctt actttttcgc ccctcctttc ttttgatgtt
     6001 tactttttga aattaaattt cttctttttt gatgaattct gtacgaatct cttgtggagc
     6061 caatagtcct gaatgaactg gatatggtcg ctcaagtaag tcaagaatgg tttgttgatg
     6121 ttctgatatg cgcacatttt cttgactcat attatagtaa cgaaggacat agccttcttc
     6181 attttccgcc actttaaagg ctgttggaca aacttgcggt atgctgagaa cagaatggct
     6241 caagaggcta ccagtcgcaa ccacgcttcc ttcctgtcta gcaagctgaa ggctggtaaa
     6301 cggtgtctgc aaggctttgg cacgacgata ggctgagaag cgttcttggg cttggtggca
     6361 ttcaagtgca aactcgactt caaactcacg caagcattgt gcttctggcg ttgggaagta
     6421 gccccagtca cctagctcac ctgatgcacg caaaatggtc acggcaatgg tgttatcccc
     6481 aaggatttcg tattcattca atcccttgtt ggatacagtc accccttttt catcgtcata
     6541 cagactgaca aaagcttgtt ggtgttgagg attttcagga ttttcccatg aagcagctgg
     6601 tttgtttggt cgtgtcacca cctcatagat actttcagaa tcattgcttg gacgcgtgtt
     6661 atgagtcttg accaagagac ggatacggtg atccttggca gtgttagtaa agcgagtctt
     6721 gaagcggatt tgtggattgt caacgaagac agtcaactca gtttccagag gaatgtttgt
     6781 caattcttct gaccgtccag cctcacgctt cataaactcg atgatacctt gttgctcttc
     6841 ttctagcttt tcatccgcac tgacaggcac ggtcaattca tgtttgagca agattttagc
     6901 atagcgatct gtgttttcca atacctcgtg gcccttaagc tctgcaaaga ttggctctgt
     6961 tccttttggt tggaaataga tatactcgtt tccgatgtca ccccggtctt caaagcggat
     7021 aaagtcttca taggcttcgt gagttgtctt gtcatagact gtgatgttgt catccacact
     7081 caccgttacg aatggtgtat caatcactcc gttttggtaa ataccctcac ggtgttcttg
     7141 ttttccttcc agcaattgga aggttgtcca agaaagcggt gctaggtgaa ctggaatggt
     7201 cacacgcact tgtcgagcaa tacgagcttg gcggaactta tcttttggta aatcgtattc
     7261 aaaattagct ccgaggtctt cgattgtagc ctctacagga cgaccatcca agtcctccac
     7321 acggtaactt ggcaagataa gagcagccat ctttttgtag ccttctgttg ggtgcaattc
     7381 cttgaaatca caagtcgcca catcaatcac tgtgctgaca gtatcgacct tatcatgcaa
     7441 gcctgtgtta atgacagtaa agagatagtc actttgagcc ttatccgtag caattttacc
     7501 cttccactca ttgagcaaat tacttttaac aaagtttcct acttggttga ccttggcaaa
     7561 acgcgtttcc atctcgcggt gaacttcgtc cacgctacag ccacagatac tatcatgtgg
     7621 cgcattctgc aaaagtgttt tccaagcata ggtcaactgg tccttgtggt tgtgtccacc
     7681 agtgataata gtcaagggtt ctaccacttg ctctaggagg ttgctatttt cttggaaggc
     7741 ttgttttagg taaatgcggg atgaagaagt gttggcaagt gtgtaccagc catctgtttc
     7801 ctgactggtc aactcacctg taacagttga taagtgttca ggaagcgcac cttctacagc
     7861 ttgaacatat tcatcaaaag aactatgaac aaagattaca tccgggaaga gttcatttgc
     7921 cacacgaatg gcttcgctca gatttttctg gacaggctgg tggtcacagc cgttcatcat
     7981 caaccattgg ttggtcgaag cgtaggcacg cacatctgac aatttttgtt tccagaaggt
     8041 caaggcctca tctttgtcaa ctgggatttc attcccatta ctgtaccagt tggcaaagag
     8101 aatacctaaa acacgactac catccacacc ctgccagtac atttctgaaa actgggatgt
     8161 aaactgctca tcttcaagga cttggttgtc aaatccaatc ggcttcacac cacgaccaaa
     8221 ggccgccacg tgaatgcctg atttttgaag aatttgaggc gcttgtccca tatttccaaa
     8281 ggtatctgga aagtagccaa tctgggttga tttaccccat ttggcagctt cttgttgacc
     8341 aatcaaggta ttgcggacat tggcttcact ggagatcaag tagtcatcct gcaagatgta
     8401 aaagggacca attttaagtt tgccctcgtc aatgtagcgt tggaccttgt cacgattttc
     8461 agggcgaatt tgtaagtagt cgtcaaggac aatagtttgt ccatccaagt ggaaactctt
     8521 gaactcaggg tcattttcaa agagatcaaa gagattgtca aacaattcca ccaactgcat
     8581 acgatggctt tcaaaaggca agtaccactc acggtcccag tgactatgtg agataatatg
     8641 tacaacaaca ttttccatga agtaaaacct cattctaaat ttaaatttta acgttttaaa
     8701 tgtaaacttg tgattctgat aagaatcggt tgagctaaag cgagcccctt agcgaatatc
     8761 caagtaatcc aagaccaact cacagaacat catgttagcc caggagaacc attcacgaga
     8821 gtagagggtc ggatcatcta cgtggaagct ttcgtgcatg acacctgtac caccatcgca
     8881 ggcaaccagc tgatccagca agaatttttt ctctgcctta tctcttgttg tcaatccttg
     8941 gatagaaagg gcgattggcc agatatagcg atagaaggta tgagaacttc cgagaccgct
     9001 agcgtattct ccttggtaga agtatggatt ttcagagctc aaaatggtac gacgagtagc
     9061 ttgatacact tcatcatcga ccgaacagta gcccagatag ggcgcagcta gtagacttgg
     9121 tacatttgga tcatccatga tgctggcatt tcctaggcca tccacttcaa aagcgtaaat
     9181 cttttcgccc ttgctgttgg tggtgtaagc gtagttttcg attccttctt ggatttcatc
     9241 ctgaagacgc ttggtatcag caataacact ctggctatca gctaggttta atgctgcgaa
     9301 gatttcttgc acataaccca agactactac agcaaacata tttgacggaa tcaagtaact
     9361 atactggcaa cagtcatcac tcggacgaaa ggctgaccaa gtcatacctg tcactgcaaa
     9421 gtcaggtcca aagccatcat ttaccaaggt gtcttcctta cggtccgtat ctcggacaaa
     9481 acgataagga gagttcttgt ggtcttgttc aactgtccat agatggagaa tttccttagt
     9541 cgctgcgaca aaagtctcat caaactgacc agtctcgcca gtctctttcc agaggagata
     9601 agccaactgc aaaggatagc aaagcgagtc cacctcatac ttgcgttccc aaatccagcc
     9661 attaaggtcg gtgtggtcgg tctcgtggtg ccccttccag ttttcctcta tgttgaagga
     9721 attggcataa ggatccttga gtaccaaggt catctgacgt ttgaccaaac ctgcaatggt
     9781 ctgacgcagg agggcatctc ttttagctac atgaaggtag ggtctgagtt gggctgtcga
     9841 atcccgaagc cacatagcag gaatatcccc agtcaagaca aaagttgaac catcttctaa
     9901 gatttcaacc gtattgtcca aggtatcggt gtagcaacgc tcgaaaacat ccacccactc
     9961 tggatggtcc ttagcccgct ctgctacttc atctagccat tctctaacaa tttctttcga
    10021 ataaatcatc gtgcaatttc ctctttcaaa caagtttcat tttcagtata tagcttttga
    10081 gacagaaaat acatacacaa atgatagtca tttttctaca aaatagttat ttttgaaact
    10141 ccttttctaa aggccctctt tttctgatat aatgtagaaa aacagctaaa ggaaagacta
    10201 tgaaaccact acttgaaacc atcgataccc gctttggtac tgctagcaag catgccttct
    10261 ctcggggaaa taccctgcca tacacaggcg tgccttttgg aatgaattac tttgtgcccc
    10321 agaccagtga ccaggatgga gcttggtttt ttgatccgca tctgcctatc tttcagggga
    10381 ttcgattaac tcaccagccc agtccttgga ttggggacta ctcttggctc cttctgacac
    10441 ccgtcaccag tcaactgggt ggagacagcc tctttcaccg ccaatcttcc tatgataggg
    10501 ataaggcctc tttccaacct cattatctaa agattttctc cctgcgctat cagattgaaa
    10561 cccagctcac accgacttgc tacggtgctt ctattcgttt gaagcaaaag caaggcaaag
    10621 ccctctccct ctatcttcac gcaacagatg aactgacagt agagcaagta gataagcgaa
    10681 ctcttgccct gcgacaagaa ggtaaaactg aaaccaacaa aaattcgcta acgatgttta
    10741 ctgccctgca aatgaacacg gatattcttg ctatcagcca agaagctggg gactggcgaa
    10801 ttgacttagc aagtagtcaa accgagatgc aactagccac ttctttcatc tctccttctc
    10861 aagctctaat caatctacct caagaagatt ttgatagctg taaaacaagt gcccaagcgg
    10921 attgggaaaa tctcctccat cgttttgaca ttatagagac aggagaggct gaccgaacct
    10981 tctttgacca ctgcctctac agactcttcc tcttcccaca gactttttat gaggttgatg
    11041 agtcagggca agccatccac atggatctgg ctactggtac tgtcaagcct ggtgtcctct
    11101 ttagcaacaa tggtttctgg gataccttcc gcaccacctt ccccctcttt gcccttatca
    11161 taccggagca ctatcaacgc tttttagaag gtttcctcaa tagctaccgc gatactggtt
    11221 tccttccaaa atggctggct ccagatgaac ggggtatgat gccaggtaca cttttagacg
    11281 gtattatcgc agatagcgcc tgcaaggacg tggcccctga cctagaagga aaactcttcc
    11341 aagccatgct cgaaacagcc agcaaagccg accctctcgg aatcaatggc cgccacggac
    11401 tagcccaata ccaagaacta ggttacctct ctaccgacca ccacgaaagt gttagccata
    11461 ctctagacta tgcctatagt gacttttgta tcgctagctg tgccaaaaaa ctagagaaca
    11521 tagaaatcgc tgaaacctac aaggctgctt cacaaaatta ccgccagcta tttgacgctg
    11581 agacaggtta catgcgagca cgagacaatc aaggaaactt tcaccctgac ttctctcctt
    11641 atagttgggg gcgagactac gctgaatgct ctgccattca agctacttta ggcgttctcc
    11701 acgacatccc tggcttaatc caactgatgg gtggaaaaga aacctttagc aactatcttt
    11761 tgaaagcttg tcaagatgct cccctctttg aaacaacagg ctatggttac gaaattcacg
    11821 aaatgagcga gatggctact gctccttttg gacaaatagc catttccaac cagcctagtt
    11881 tccacattcc ttatctcttc cgctacagcg attaccctga ctacactgcc cttcttatca
    11941 agacgctccg tcagaaagct tttcacccaa gttgggaagc ctatcctgga gatgaagaca
    12001 atggtagtct ctctgcttgg tacatctggt cagctctcgg attttatcca acctgtccag
    12061 gaaaaccaag ctatgacctc ggaatccctc tctttgacca tctacgagtc tacctcgcta
    12121 aagaagataa atggctggat atccatacta aacaaaacca caaccatttt aactttgtca
    12181 aagaatgccg actggacaaa acactcgtat caactattca acaccaagac ctcttaaaag
    12241 ctgaacaact aactttcacc ctcagctggt taccaagtca ctaataacca aaagaacctt
    12301 tgcatcgcgc aaaggttctt cttttatgaa acttggactt gaagttgatc cacaagctga
    12361 ccatccaccg ttaggttcag atagaaatcc aaggttttat ctcctgcgaa atacagggtt
    12421 ggtagatgca aatctttttt gctttcccct gcttggaatt gaaggacttg aatctcatcc
    12481 tgataggcga caccatggac acctgtcccc ggttgaatcg aaatcttagc ctctaaagag
    12541 gagctacttt cactacgttc aatcctaaaa tgaagagtct ctccctttgc cacagctagg
    12601 cttttttctg caaatgctag ttcctgaaca acttcttttt ttgataatcc aggagtttta
    12661 caaagggaaa tcttggtcaa tacaggaata gattgtgcct cggtaatcat cacgcgcacc
    12721 ttttgtgcct ctactagcgg acctcgcaag aggcgcttat gaccaactgt gaagcccctg
    12781 ccaaattcct gccagacacc atccacctct acttgcacat gaaaagcagc gattcgttgc
    12841 cctagcttca aatcttctct taactcaatt acatcaaaag ttttaggaga acctaaatcg
    12901 agttctaact ggatgggcaa gtctgcatcg cttgcccaag agctggtctc aaggccgtct
    12961 gtcaaatggc gacaagcaaa gtctgcggaa agagctggac cagatacctc agctcccaga
    13021 gccaaatctt ctttatagag ctcattgcga taggtcgcaa attcataaag tcgttcaata
    13081 tcctttgcat caaagagccc agcttgattc ggcggaatat taagcaagag tggagttcct
    13141 cgccctactg agtgaaagta gatttcgacc aactcctcga gagacttagg atcctgatcc
    13201 tcatggtaga accagcctgg acggatggaa acatctgcct ctccgatcga aaaaatcgtg
    13261 cccgagggat ccccgtgctg aagatagttc agctctgctt ctgttcctag tttatcagga
    13321 ttcatctttt gccacagtgg atcacctgca tgccctcgtt cattgccaat ccagtggata
    13381 ctggtgcctt ctgttgaaaa aatcaaacaa tcgccctgca agtcacgaat ggtttcaaac
    13441 catttttcaa attcataatt aaccttttgc gcgccctctc ctctggcacc atccatccaa
    13501 acctcagcga acttaccagc attcccatag ttaggatttg ataagatttc cttcaactga
    13561 gccagataat aggcattgta gtccgcttct cggtccacat gatagagggg actatgggca
    13621 tcccacggtg acaggtagac ccccatatcc atatcaaact ctgtggcagc ttgggatact
    13681 tcaaggagca agtcgccctt tcctctcctc caaggactga ccttaaccga ataatctgtg
    13741 tgagctgtcg gataaaggac aaagccatcg tggtgcttga ccaccaaaat caactttttg
    13801 aagcccgttt ccttgagcac acgaacccac tcacgcgcat ccaactgact cgggttaaag
    13861 cgctcaggat cctcctgtcc agtcccccat tcttggtcat aaaaggtatt aggaccgaag
    13921 tggataaaag ctgctagttc atctcccaga taagctagct gagtctgact tggtaacggt
    13981 ccatgcggtt tgattttctt catcgttata tatctccttc tttagcaact tctcttattc
    14041 acaaggttat ccacaggttg tggataataa accatgatct aacagtcagc tctttccaac
    14101 tccaactggt aggctcagga tttttctcct caatattccc tcttcaaaca gctctgtcat
    14161 atggttctgc taacacctct cagaatgcta ctctccataa ttattctcag gcttctttca
    14221 ggtcattgtg tgaagaccat tcactatcca gacttttcca cagattgtga ataagtgatt
    14281 attctaagct atcacctcgt cgactataac aaaaaataaa aagagggtca ataagataat
    14341 tatctcttcc taaatactca gaaaagattc tataatttgt acaattgaac aagaaatgct
    14401 tctccaaaat ctatcttcaa aagaatgttg catcttttta tcctttcaca caaacatttc
    14461 tctttataca gatccaagtg ataaccagat gataattgga cactttttgg tcatttgtat
    14521 attttttgaa aaatttttta aaaaaatttt atatcctttt tatagaagtt tatgcatttg
    14581 tatctatgta ttctatccta tgttatgtat aataacataa aattgtgcta aacatcataa
    14641 tttatattat tttccgagaa attatagcca ttgacattac ctaggaattg cgttataaca
    14701 tacatgtaag cggtacccaa aatggtgcca agtcaaaatt tttaaggagg aaaatacatg
    14761 tcttctcatc caattcaggt cttctcagaa attgggaaac tgaaaaaagt tatgttgcac
    14821 cgtccaggca aggagttaga aaacttgttg ccggactatc ttgaaaggct tctttttgat
    14881 gatattcctt tcttggaaga tgctcaaaaa gaacatgatg catttgccca agctcttcgc
    14941 gatgaaggaa ttgaggttct ctacctagaa caactcgctg ctgaatcatt gacctctcca
    15001 gaaatccgcg atcaatttat cgaggaatac ttagacgaag ccaacatccg tgatcgtcaa
    15061 accaaggttg ctattcgtga attacttcac ggcatcaagg acaaccaaga attggttgaa
    15121 aaaacaatgg ctgggattca aaaagttgaa ttgccagaaa ttcctgacga agctaaagat
    15181 ctaactgact tagttgaatc agagtatcca tttgcaattg acccgatgcc aaacctctat
    15241 ttcactcgcg acccatttgc aacaattgga aacgccgtat cgcttaacca catgtttgca
    15301 gacactcgta accgtgaaac actctacggt aagtatatct tcaaatacca cccaatctat
    15361 ggcggaaaag tggatttggt ctacaaccgt gaagaagata cgcgtatcga aggtggagac
    15421 gagctagttc tttctaaaga cgtccttgca gtaggtatct ctcaacgtac agacgcagct
    15481 tctatcgaaa aacttttggt caacatcttc aagaaaaatg ttggcttcaa gaaagttttg
    15541 gcctttgaat ttgctaacaa ccgtaaattc atgcacttgg atactgtctt cactatggta
    15601 gactatgaca agttcactat tcacccagaa atcgaaggcg accttcacgt ttactcagtt
    15661 acttacgaaa acgaaaaact taaaattgtt gaagagaaag gtgacttagc tgaacttctt
    15721 gctcaaaacc ttggtgtaga aaaagttcat ttgattcgtt gcggtggtgg caatatcgta
    15781 gcagctgcgc gtgaacaatg gaacgacggt tctaacactt tgaccatcgc acctggtgtg
    15841 gtagttgttt atgaccgcaa taccgtgacc aataagattt tggaagaata cgggcttcgc
    15901 ttgattaaga ttcgcggaag tgaattggtt cggggccgtg gtggacctcg ttgtatgtct
    15961 atgccatttg aacgtgaaga agtgtaatag ctgttcggca ttcgtcaata gaaaatgtaa
    16021 aaaatagaaa gaggaaataa taaaatgata aattcagtat tccaaggacg cagcttctta
    16081 gcagaaaaag actttacccg tgcagagtta gaatacctta ttggtctttc agctcacttg
    16141 aaagatttga aaaaacgcaa tattcaacac cactaccttg ctggcaagaa tatcgctctc
    16201 ctatttgaaa aaacatctac tcgtactcgt gcagccttta caactgcggc tatcgacctt
    16261 ggtgctcacc cagaatacct cggagcaaat gatattcagt tgggtaaaaa agaatctact
    16321 gaagatactg ctaaagtatt gggacgtatg tttgacggga ttgaattccg cggattcagc
    16381 caacgtatgg ttgaagaatt ggcagaattc tcaggcgttc cagtatggaa cggtctaact
    16441 gacgaatggc acccaactca aatgctcgct gactacttga ctgttcaaga aaacttcggt
    16501 cgcttggaag gcttgacatt ggtatactgt ggtgatggac gtaacaacgt tgccaacagc
    16561 ttgctcgtaa caggtgctat ccttggtgtc aatgttcaca tcttctcacc aaaagaactc
    16621 ttcccagaaa aagaaatcgt tgaattagca gaaggatttg ctaaagaaag tggcgcacat
    16681 gttctcatca ctgaagatgc tgatgaagca gttaaagatg cagacgttct ttacacagac
    16741 gtttgggtat caatgggtga agaagacaaa ttcgcagaac gtgtagctct tcttaaacct
    16801 taccaagtca atatggactt agttaaaaaa gcaggcaatg aaaacttgat cttcctacac
    16861 tgcttgccag cattccacga tactcacact gtttatggta aagacgttgc tgaaaaattt
    16921 ggtgtagaag aaatggaagt aacagacgaa gtcttccgca gcaagtacgc tcgccacttc
    16981 gatcaagcag aaaaccgtat gcacactatc aaagctgtta tggctgctac acttggtaac
    17041 ctttatattc ctaaagtata attttagata ataaaccgtc taccaacagc tatgagggct
    17101 gcgactaata gctttagtcc ggtcctcttt tatgtaatgg taatctatta tttcttataa
    17161 aatatgtgaa aaatcattaa attgaaatct aaacgcattc tattgagtgt gataaaggag
    17221 aatttatggc aaatcgtaaa attgtagtag ctttgggagg aaatgcgatt ctttcttctg
    17281 acccatcagc aaaggctcaa caagaagctt tagttgaaac agctaagcat cttgtaaaat
    17341 tgattaaaaa tggagatgat ctgattatca ctcacggtaa tggacctcaa gttgggaatc
    17401 tcttgctcca acatttggca tcagactctg aaaagaaccc tgccttccca ctcgactcac
    17461 ttgtcgctat gacagaaggt agcatcggtt tctggttgaa aaatgctttg caaaatgctc
    17521 tcttggatga aggcatcgaa aaaaatgttg cctctgttgt aacgcaagtt gtcgtagata
    17581 aaaatgatcc agcttttgtt aacttgagta aaccaatcgg tcctttctat tcagaagaag
    17641 aagcaaaagc agaagccgaa aaaagcggag cgactttcaa ggaagatgct ggccgtggct
    17701 ggcgtaaggt cgttgcctca ccaaaacctg ttgacatcaa agaaattgaa accatccgta
    17761 ctcttttaaa taatggtcaa gtcgtcgtag ctgcaggtgg tggcggtatt cccgtcgtca
    17821 aagaaaacaa tggacatttg actggtgtcg aagcggttat tgataaagac ttcgcttccc
    17881 aacgtttggc agaattggtt gatgcagacc tcttcatcat tttgacaggt gtagattatg
    17941 tatttgttaa ctacaacaag ccaaaccagg aaaaattgga acatgtgaat gttgcccagc
    18001 tggaagaata tatcaaacaa gatcagtttg caccaggtag catgcttcca aaagtagaag
    18061 cagctatcgc ttttgtcaat ggtcgtccag aaggaaaagc agttattact tcccttgaaa
    18121 atctaggcgc cttgattgaa tctgaaagcg gaacaattat tgaaaaagga taagttgttt
    18181 tactaataag atgtattcta tttctagtat ctttatatca aattagaaat tattcttgaa
    18241 aacatgtaca atatttcaaa agatattagt tttttagact ttaatatggt aaaacaaata
    18301 taaatagaaa gcgttttctt gaatgtttat ttaagaaagt agttggtttt ttacactttg
    18361 ttagacatca ggaggaaaaa caaatgagtg aaaaagctaa aaaagggttt aagatgcctt
    18421 catcttacac cgtattattg ataatcattg ctattatggc cgtgctaact tggtttatcc
    18481 ctgcgggggc ctttatagaa ggtatttacg aggctcatcc tcaaaatcca caagggattt
    18541 gggatgtcct catggcaccg attcgggcta tgctaggtac tcatccagag gaaggttcgc
    18601 tcattaaaga aacgagtgca gcgattgatg tagccttctt catccttatg gttggtggtt
    18661 tccttggcat tgtcaacaaa actggtgctc ttgacgtagg gattgcctct atcgtgaaga
    18721 agtataaggg ccgcgaaaaa atgttaattt tggtactgat gcctttgttt gccctcggtg
    18781 gtacaactta tggtatgggt gaagaaacaa tggccttcta tccactcctt gtgccagtta
    18841 tgatggccgt tggttttgat agcctgactg gtgttgcaat tattttgctc ggttctcaaa
    18901 tcggctgttt ggcatctact ctgaatccat ttgcgacagg tattgcttca gcgactgcgg
    18961 gagttggtac aggggacggt atcgtacttc gtctgatctt ctgggttacc ttgactgctc
    19021 ttagtacttg gtttgtttac cgttatgcgg ataagattca aaaagatccg actaagtcac
    19081 tggtttatag tactcgcaaa gaagatttga aacactttaa cgtagaagaa tcttcatctg
    19141 tagaatctac acttagcagc aaacaaaaat cagttctctt cttatttgtg ttgacattca
    19201 tcttgatggt attgagcttc attccatgga cagaccttgg cgttaccatt tttgatgact
    19261 ttaatgcttg gttgactggt cttccagtta ttggtaatat tgtcggttca tctacttctg
    19321 cactaggtac ttggtacttc ccagaaggcg caatgctctt tgcctttatg ggtatcctga
    19381 ttggtgttat ttatggtctt aaagaagata agattatctc ttccttcatg aatggtgctg
    19441 ctgacttgct cagtgttgcc ttgatcgtag cgattgctcg tggtattcaa gttatcatga
    19501 acgacggtat gattaccgat acaatcctca actggggtaa agaaggcttg agcggtctat
    19561 cttcacaagt ctttatcgtt gtaacttata tcttctatct acctatgtca ttcttgatcc
    19621 catcttcatc tggtcttgcc agcgcaacta tgggtatcat ggctccactt ggagaatttg
    19681 taaatgtccg tcctagcttg attatcactg cttaccaatc tgcttcaggt gtcttgaact
    19741 tgattgcacc aacatctggt attgtgatgg gagctcttgc acttggacgt atcaacattg
    19801 gtacttggtg gaaattcatg ggcaaactcg tagtcgctat tattgtagtg accatcgccc
    19861 ttcttctcct tggaaccttc cttccattcc tataaaatag tgagtgaggt gattccatga
    19921 aaatagatat aacaaatcaa gttaaagatg aatttcttat atcattaaaa accttgattt
    19981 cctatccttc agtactcaat gaaggagaaa atggaacacc ttttggacaa gcaatccaag
    20041 atgtcctaga aaaaacttta gagatttgtc gagacatagg tttcactacc tatcttgacc
    20101 ctaaaggtta ttacggatat gcagaaatcg gtcagggagc agagcttctg gccattctct
    20161 gtcatttgga tgttgttcca tcaggtgatg aagcagattg gcagacaccg ccatttgaag
    20221 caactatcaa agacggctgg gtattcggac gtggtgtcca agatgataaa ggcccttcgc
    20281 tcgcagctct ctatgcagta aaaagcttgc tggaccaagg tattcagttc aaaaagcgcg
    20341 tacgctttat ctttggtacc gatgaggaaa ccctctggcg ctgcatggca cgctacaata
    20401 ccatcgaaga acaggccagc atgggctttg cacctgactc atcttttcct ctgacctatg
    20461 ctgaaaaagg gcttctacag gtcaaacttc atggccctgg atcggatcaa ctagagcttg
    20521 aagtaggagg cgcctttaac gttgtaccag acaaggccaa ctaccaaggt cccctctatg
    20581 aacaggtttg taacggtctc aaagaaactg gttatgatta ccaaaccact gaacaaaccg
    20641 taacggttct cggagtgcca aagcatgcta aggatgctag tcaaggtatc aatgctgtca
    20701 tccgactagc taccattctt gctcctctcc aagaacaccc tgctctcagc tttcttgcaa
    20761 cacaagcagg tcaagacggc acaggaagac aaatctttgg tgatatagca gatgaacctt
    20821 ctggtcacct atcctttaat gtcgcaggtc tcatgatcaa tcatgaacgt tctgaaatcc
    20881 gtattgacat tcggactcct gtcttagctg acaaggaaga actagtagag ttgcttacaa
    20941 gatgtgcaca aaactaccaa ctccgctacg aagagtttga ctatctagcg cctctatacg
    21001 tcgcaaaaga cagtaaactc gttagcacac tgatgcaaat ctaccaagaa aagactggcg
    21061 ataacagtcc tgctatttca tccggtggtg ccacttttgc tcgcaccatg ccaaattgtg
    21121 tagccttcgg cgccttattc ccaggagcga agcagacaga acatcaggca aatgaatgtg
    21181 ccgttctaga agatttgtac cgtgctatgg atatttatgc cgaagccgtc tatcgacttg
    21241 caacttaatc aggcaactgt ttctacaaaa aaaaatcgac cgattaatga actgcacccc
    21301 aaaagttaga cagaataaat ctaacttttg gggtgtttta ttatgaaatt gaattatgaa
    21361 gataaagttc agatctatga actaagaaag caaggacaaa gcttcaaaca gctttcaaaa
    21421 agatttggtg tggatgtttc tggtctaaag tcatctgaat ctttgagatg agctttataa
    21481 atcgcttttt tcagtttttg cactggtatt tcgataaact caaacttttt agccgttgta
    21541 ttgcctgatt ttatagtatg ttgaaactag aatagtacac ctctacttct aaaacatttt
    21601 tagaaatcaa tttgactgtc ctgattgatt tgtcctgttc ttatttcatt ttactatatt
    21661 tgagccactt cgtctttaac ggctttattc ataagctctt gtaatttttc tttactatca
    21721 attacttctg attttccgtt gtaatttatt gtaataggtt ttaacttacc taatttctcg
    21781 acacgctcat taatttgatc ttttttgaag gctgcatatg tttttcctaa gattttttcg
    21841 aaaatatatt tatcagatag cggtttgcct tcttcttcag cttggttttt gtattgattt
    21901 gaaacataag gaacaaatcc ttcatagtaa cctaatgctc ccataagttc aaaagcttgt
    21961 tttctaattc aaaccattgc aactcagatt tcagcttttc agataaatcc tgctcatcca
    22021 aataatgact tgaaattagt gctgaactcg tttctgtatc ctgtacaggc tgagcaccca
    22081 taccagcaaa aaaataaact cgttcctagc aagaccgaac aagctcctat tgcatatttc
    22141 ctcaaagaaa aacgctgctt tctctcaaat tgaaattctt tcatcccatc tcccatcatt
    22201 cattattact gtatattttg tatatcagaa atagtttgta ttcacaaatc tttctagtta
    22261 ttcccttatc attcctaatt aagggagata acatacaata atttttagtt aaatgtatat
    22321 cgatgttttt tgtttttctt aataaacgca atacaaaaag agcctgttgc caagctcttt
    22381 atactcaatg aaaatcaaag agcaaactag gaaactagct acaggttgct caaaacaccg
    22441 ttttgaggta gtagataaga ctgacgaagt cagctcaaaa cactgttttg aggttgcaga
    22501 tagaactgac gaagtcagta acatctatac ggcaagacga cgctgacgtg gtttgaagag
    22561 attttcgaag agtattagtc tattatttct tctcagcgcg aagggctgac aagatttgtg
    22621 tacggatatc atccacacca tttggagtat ttggtaaaaa gatggtttga tttcctttag
    22681 aggcaaaggt attcaaggta tccaaatact ggttggtcaa gaggatagac atgatttgtt
    22741 cttctgtcat gccaacattg gcttccttga gttcggtgat agactctgcc aatccatcca
    22801 caatcgcctt acgttgttgg gcaatcccca caccatgaag gcggtctttt tctgcttctg
    22861 cttcagctgc agtgacaatt ttaatcttgt cagcttccgc caattcttgt gctgcgaccc
    22921 gcttacgttg cgccgcattg atttcattca tggattgctt aacttctgca tccggttcga
    22981 ccttggtaat caaggttttc acgataatgt agccgtaagt ggtcatttct tctgctactt
    23041 ggtgttgaac ctcaagggca atctcatctt ttttctcaaa caattcatcc aaggttaatt
    23101 ttggaacaga agagcgaaga gcatcttcga tataagattt aatctgagat tctggacgta
    23161 tgagtttata gtaagcatct gtcacgctct gctcgttgac acggtactga gtcgctacat
    23221 tcatcataac gaacacattg tccttggtct tagtctcaac cacaatatca ctttgcaaca
    23281 agcgcaactg aatccgtgct gcaatcgagt caatcccaaa aggcaagcga atatgaatac
    23341 cgctattagc aaccttttgg tatttcccaa agcgttcaat aatcgccacc gactgctgac
    23401 gaaccacata aactgtactc agtgtgacta tcaccaatag gagcacacaa acaatcagaa
    23461 aaatcatgaa aaatattgcc ataatggaac ctccacaagt atttttctag tattatagca
    23521 catttaaaga aggctgtgcc gtttttactg cgattttttc tgaaatgtca ataattagag
    23581 gtgaattgtc ctattgtcgt ccaatccttg ctaaaataac tctttataaa aggcaatcgt
    23641 ttcttctaag gttggcataa atggatttcc tggtgcgcag gcatcaatca aggcattctt
    23701 agaaaggtat tcaaagtcga aatctttttc ttcaatacca agttcagtca gtttcttagg
    23761 aatacctact gtctcagaaa gcttctcaat ctcagcaatc gcataatcgg cacattcttg
    23821 atctgattta ccttctacat gaagtcccaa ggctttggca acattgcgga aagcttctgg
    23881 tacacgttta gcattttcac gttctataac tggtagcaac atggcacagc aaacaccatg
    23941 tggcaaatta tatactgcac cgagttggtg agccattgag tgaacatagc caagaccagc
    24001 attattaaag ctcataccac caaggaagat ggcattgacc ataccttcac gcgcttcaat
    24061 atcatgtccg tttgctacag cacgaggaag atattccttg ataagctcaa tagcaccaat
    24121 agacagtttc ttggttacat cataagcacc aggtgttacc aaagcttcaa cagcgtgagt
    24181 cagagcatcc ataccagtag cagcagtcaa ggcttgaggt ttggaaagca tgagttcagg
    24241 gtcattgaca gaaatcaagg caaggctatt cttgtcaacc attaccatct taaccttgcg
    24301 ttcttcatca gtaatcacat agttaatggt aatttctgct gatgtacctg ccgtagtatt
    24361 gatagctaca acaggaaggc cttttttagc agacttatga agcccttcat aatcctgtgg
    24421 ttttccacca tttgtaacca tgatagaaat acaactagct gcatcctgtg gagaaccccc
    24481 gccaagactg atgataaaat cacatccatg ttcttgcaaa gcagctaccc catctgtgac
    24541 attcttacaa gtagggtttg gctctacatc gctaaagatg acatattcga ttccttctgt
    24601 atccagtggt tttaaaacct taggtaaaat gtcactgcct tcgatgtact tatctgtcac
    24661 caaaagtgcc tttttatagc caagttcctt gatataagga cccacttcat ttacaacacc
    24721 ttttccaata aggttgactg ccggaacata aaatgtagcc atataatttt cctcctgcgc
    24781 ctttgcgcta tctatttaac atcattatat tactttttgt attcgttttt aattatttgt
    24841 gaattgttta acaaatcttt ttaaaaggat aggagggacg taagttcacc tcctatataa
    24901 acaagtttta tttatgtagt ggtcccaaca actgacatgc acgatagtct gctgattcta
    24961 gatcttctgt tccaaataag gaccaatttt taggtctaaa gatatcttcc tcaggtacat
    25021 tatgcatatt gacaggaatt ctcaacatag aagccaaggt aatcaagtct gctccaatgt
    25081 gtccatatgt tatggctccg tgattagctc cccaattatt catgacgtca tagacagact
    25141 tgaaagcacc ttttcctgtc aaacgtggag caaaccaagt agttggccat cctggatctg
    25201 tacgattatc taaagtatgg tgaacatctt caggaagttc aagtgtgtaa ccttctgcaa
    25261 tttgtaacac tggaccaacc ccttttagaa gattgagacg taccattgtt actggcatat
    25321 cccccttcgt caagaaacga gttgagaatc ctcctccacg gaagtattcg cggtttgctg
    25381 gtgggaagtc tgtattttca agcatagcct gcacttcact ttcttccaac tcccagaatg
    25441 gtttcataac aggtttgcca tctcgagtag cttgacctgt accatccaat gtacaagaac
    25501 cagagttgat tagatgtaag aagccagctg cagcacgacc ctctaaagta tgtcccgtta
    25561 cacgtttaac agcctctgga ctccaataag tacgcacatc agcaaatatt tgtggagtat
    25621 ttgttaatag ataattaaag agcatagaca caccatttag tgaatcattc tctgtcgcaa
    25681 atacaaatgg ttttcgaata ccattccagt caaactgagt attgaggaaa gtttccataa
    25741 agtccccatt tgggaaatga tctgtccact ggcgttgacc ttggaaacca gctactaaag
    25801 catggtgacc aactgcttct tcttcaaaac caagttcagc aagtcttggg ttaccaacca
    25861 ttaagtcacg tccaatcatg aacatcttaa taacaaattc ccattgtttt tctttctctt
    25921 ctttagaaag aatcaaatcc tcacgatttc ggtcaacccc ttctttgata tgttctttta
    25981 cccaaaccat agcacgttcg aactcttctg ggtcataaat accacggtcc atacggcgcg
    26041 tgaactccgt catatctacc gattcatttc gcattcctaa gtattcttgg aagaaatctg
    26101 gatttacaat agaaccacca atccccatcg aaacactacc cattgatagg taagcagtgt
    26161 ctctcatcaa gccagttgca agagctgcac gcgcataacg taaaagtttt tctttgacat
    26221 cttctggaat agctgtgtca ctagcttcct gaacatctct tccataaatc ccaaaggctg
    26281 gaatcccttt ttgagcatgt gaagctagta cagctgcaag atagacagct cctgggcgtt
    26341 ctgtcccatt aaatccccaa atagcatgag gaatatctgg agacatatcc atagtttcac
    26401 taccataaca ccagcatggt gtaactgtaa ttgttgcgca aacatttgat tttttaaaca
    26461 actcatggga agctgcagcc tctggaacac gaccaatggt agatggagaa atcacacatt
    26521 ccacaggttc cccatctgga tatttcaatg tgcttgaaat caaatctgcc acacttttag
    26581 ccatgttcat tgtttgtact tcaagtgatt cgcgtacacc ttgacgacga ccatcaatag
    26641 tcggacgaat cccaatacgt ggatgttgaa tcatactatt ttcctcttat ttttctgttt
    26701 ctttcatact accgatgata atttttaaaa ttacttataa gtataaacct ctacctctgc
    26761 caaacttaaa ggaattcctg cgtttctcaa agaaattcta accttttttc ccttcagccc
    26821 ttttaagtct atggatagat tattgctttc taaactgtca atatgttgtt taaaaacttc
    26881 atgattattt gaatcatata taataatatc aaaatttgat aatctctgaa tttcagcatc
    26941 tgttctatta taaataatta acttttctaa ttcttcggtt tgtgctaaat ctatctccca
    27001 ccatgaagga gaatctcctt tggtatgagt cactgaatga tgaccataat ctccgttttt
    27061 atttccatca actgctagac gagaaaaacc attgtaatcc gttgaactct gtcgagtttc
    27121 tttggttaat gcaatattag aaagtttctt cggagttctc tttgaaccat agacttcaac
    27181 ttccgctaaa cttaacggaa tagctgctga ttttaattct attttgacta gcttagcccc
    27241 tacagaaggt acttttaaag ataacaaacc atcaactact ttatcaaaat gtcttctaaa
    27301 aacttcttct cctgatgaag atagaaaaat aacatcaaaa ttagataaac gctgaggttc
    27361 ggcatctgtt ctattataaa tatcaacttt agaaaccgta aactcttctc ccagatcgac
    27421 ctgccaccaa gcgttagaat ctgccttagt atgagtcacc gaatgatgtc cgtaatctcc
    27481 atctttatta ccatcaactg ctaaagcagc tacaccctca taattggttg aactttgagt
    27541 agctacctta tttgtagaga ctactttatc ttctgttatt ttatctatat cctcttcaga
    27601 ttgcttacca tctgattctc taaaaacctc tacttctgct aaactcaaag gcactccact
    27661 cgttagtaat ttaactttaa tataccttgc tcctttttct ttgaaatcta gactaacaga
    27721 ttcacccgac aaattattaa catgtttctt agcaacttcg tttctattat tgtcatatag
    27781 aatcacatca aaattagata gacgttgagt ctcagcatct gtgcgattat aaattttaac
    27841 aagcccaact ttatccattt ttttcaaatc gacttcccac caagaaggat tatctgccct
    27901 agtgtgtgtt accgaaccag agttaaaatt accatttctg ttaccatcca cagctctatt
    27961 agggtctcca ttgtaatcta cagaactttg tgttgttggt tttgcatatg ctatattcaa
    28021 attaccatca ttaaatttat ctggtgttgg gaaagggact gggcctgtcc cttcagtatt
    28081 tatagacatc tctaccattc cattatgatt aaccgtaatg gtataaacat gggtattctc
    28141 atcccaattt tctgtataag tataatgatt tttatcgcca cttatattta tctgaggttt
    28201 atgaccagta tgccctttta atgtaagtgt tgttgtccta aagtcattat ctacaggatt
    28261 gatggaataa tttttgctta tccagttcgc taactctaat tcttctttct tccaactttt
    28321 tgatgcatca aaatttcctg ataatgccca catagctgtc ttatctgtcc tgtaattgtt
    28381 caataaaata tgtaaattat ttggattttc tttaacaaca gcgtaagtat gtggcgtcaa
    28441 atctaacgat aacgactttg tattattagt atacataggc aacattactt gctgattttt
    28501 attgatatta gcattactat tataaatata ccaggaatta cctacacgct gagcataccc
    28561 atctccttca taaagttttg gataaagcga gtttaaatag ttgactttac tagacaattc
    28621 ctcactattt ttagtcaaaa tttttgcatt agggaatata gatgaaatct tttccttatc
    28681 aattttctca tgtattacag gaagaatatg atatctccca ttattatata aaggcattgt
    28741 ttcatcattc gaataaagtc cttgataaaa tccgtttaat gaactaatcc taccttctcc
    28801 attccaaaat acagcttttg ttctatttac aacttcttcc ttacttggag ctggattttg
    28861 tatagcatgt ctaaagaaag gaataatacc tttagtaaat gctggagttg gtacatcatt
    28921 tgtcataaat gtatacgcgg cacattcaaa attataaact gtgcctcccc cagtatatac
    28981 attcatcatt tccatagcaa tcattgattc tggttccgat gcataggatc tcatatccct
    29041 agctcttcca gtttcaaatg tgtttgtata atgtttttcc caccatttcc atgtatctgt
    29101 tgatgagccc cagttatcac ataagccact caaccaaaat ccactaacga tagaatctgt
    29161 acccgcatca tctcttattg gcgtattttt agttgccaac accaaatttt tatgatattt
    29221 ttgactcgct tcaaagaatg tcggatcatt cataatagtt tcccagaacc atttttcatg
    29281 atcatgccag ataaaatgcg ctccatattt ggcacaaact tccaaatatt tagcactatg
    29341 cggagctaac tggttattgt aaatccaata attctcaata tttaaaacac cttttaacac
    29401 actatacttt tggaattgtt catctaacca ctctggagga actgtattac gctctccagc
    29461 cgacataata accaagaaaa ctggaatgtt tagactttga gcttcctcca acatcttgac
    29521 ataccattct ctcaattctt tcgtatctcg tggaatacaa cttgttggtt tacagacttt
    29581 tgcaggatga agttcaatcg ctgcatatgg ttttacatct tcaggaatag cttcccatgc
    29641 tcccttcaat gtgttccccc accataatcc gttaccatta tcattgccat acaacggaga
    29701 aagcaacaat ggcgattcat tattaatcgt cgttctcatt tgaacacgat tatcagcctt
    29761 aactcctgct aacaatccaa aacataacat cccaatacat acaaacagta ttgtgattaa
    29821 ttttcttttt attttttctt tattcatgac ttatacctaa aaatttaact caataatttt
    29881 ttctgaatta aataccaatt caatattttg tacatcagta tttttgccat atattcttac
    29941 tcttactttt tgatctttgt ttcctccttc caattttagg aatgttatat ccccattttt
    30001 ccaagcaaac gataccttat atcctcctct tactctgaaa cctttcactt ctccttctga
    30061 ccaagcagaa ggtaaagctg gaattagtga taaccaatta tgatggctct gtactaataa
    30121 ttcacaaatt ccactcacca aacctaaatt accatcaatt tgaaatggtg gatggtcaag
    30181 aaataaattg ccaagagtcg cattatttaa caaaccatta atctggttat aagcaggttc
    30241 accttgatat agtctcgcaa aaaaatgaat cagccatgca gcactccaac ctgtttgtgt
    30301 actagcatgc aaaccactta ctaaccaatt attaatcgct tgctccctct cctgtgaaga
    30361 taaaaagtta gcgtttgata atctcctatt gatagtgatt ttagctgctt ctgctaattc
    30421 cggagtttta tgaatatcaa tctcattata aggataaagc ccaaatagag gtgaaatgtg
    30481 tctatgccca ggctctactt cttcataatc ttctaaccat tcttggattt gcccattact
    30541 acctattttt gttttaggta gtttcttttt taactccttc acacgactaa taaaatccga
    30601 attgtctcct aattgttttg caatgccaat gcatgaatca caaaaatatc ttagaatttg
    30661 attatcaatt gtagatgata gacaagcatt tccttcaata ccatttttta agcgatattt
    30721 attttccggt gagacacttg gacctgtcat caagtagcca tccacctcaa ataaataatc
    30781 ttcaaagaaa agaaatgctt cttttatcat ttcaaaatgt tccgtaagaa tacgctcatc
    30841 ttggaaatat aaatagtgtt cccaaatatg agtacataac catggaatag ttaataccca
    30901 aattgcagcc cccatggcat gagattgggg agccgtatcg ccaaaaccat ccgtattatg
    30961 atgtgctgta aaacctctag ctccatacat tttcttagcg gttagtcttc ccggttctct
    31021 cattctttcg agcatatcaa ataatggata ttctacttct ggtaaatcac atggacctac
    31081 catccaataa ttcatttgag tattaatatt aatcgtatat ttagaacccc aaattggatt
    31141 taattcatca caccatattc cttgaagatt gacaggtaaa ccattcggtt gactagacga
    31201 tattaacaga tatcttccat aatgaaataa caagttagtc aagtagttac tatacttttt
    31261 agtgttttca agaagtagat tcgttggaat gctaagacaa tctttactat agtctagttt
    31321 aaaatcaact ctattaaatt gctcctgata tttttttaca tgttcatctt tttctgtaaa
    31381 gtaatcaata ctactaaatt ctccctgaag agaagaaata tctatatttc cccaataatc
    31441 cgtcattgat ttgagataaa gaaatacctc tgtagcattc cgaataacta ttgtctctcc
    31501 caatacactt acttcaccat ccgtaacttt agaatgacat actactttaa actgaacacc
    31561 ttttctacct ccagcagagg ccgacattaa aattgtactt gaatccagtt tagatacttc
    31621 gtcattaaac cgtttatttc tacccaaatt aatgtttaaa tttaatgtgt tttgaactga
    31681 tgacactata cggcaacata aaatattctt attaaaactc gtaaaatatt ctctttttat
    31741 ttgtaaatta caactattag gctcaaacac aacattagaa atagctgtat ctaaatctag
    31801 ctctctttca tacaatgaaa gagcacaaga ctgaatatct atatgctcaa tgtaaagttc
    31861 cccaagtaat tcatagtggc tttgatctct tggggtagca aacattgtta actttatcaa
    31921 ttcttcggct ttctgaattt ctccatctaa aagatattcc cgaatttttt taagatgcaa
    31981 tagtgagtct ggattatttc tatctgactt tcctctatac caaatagtct catcgtttag
    32041 ttgaatacat tcttttgtag ctgaaccata aatcatacca cctaaatgac cgttcccaat
    32101 cggcaaggct tcattccaat ttgaggcagc tttcttatac cataatttca ctctttacct
    32161 ctcttccaaa atggaggtga tatcccaaat accacctcca cactttctac tacttcaaaa
    32221 ttcctaaaac aactaggata actccaatag ccataacact aaagattagt acaaccggat
    32281 tctttccttt tctaattaat ttacacatta ataaagtcaa agccataggg ataaatcctg
    32341 gaattaattt tgtaatcatt tcttgaacag aaataacaag ttccccctgc ttaaattcta
    32401 atccaaaatt aataccaacc attgatggaa tcaaaccacc cactagtact agccctaatg
    32461 ctgtcgccat actcgtaacg cgattcaatg ttccttttgt attattttct tggataagac
    32521 tagaaccctt agtataccca tatttcaaac cgaaatattt aacaggaata ttaataatat
    32581 taaacaatat taaggcgata aagataccta aagcaccgcc gtctttagaa taagacgcac
    32641 caatactaaa acagatagga actagtgtca gccagaacaa actatctcct agaccagcca
    32701 gtggccccat caagccaact ttaataccag taattgaagc tgcaccttca tttccttctt
    32761 gttcttccat agcggaagta actccaagaa taaatggtgc cgctgtttga tgagtattga
    32821 aaaactcaag gtgacgtttc attgcaggag aagctgaatc tttgtctggg tatagttttt
    32881 tcaatactgg aagaattgta tatagaaaac ctaggttctg cattctctca tagttccatg
    32941 aagaaccata cataaaactt cgtttgaaaa cttttttaag ttcaacttta gttactttat
    33001 tattcatcat agatcaagat cctcctcaac atcactactt gaagttgttt cttgtggttt
    33061 acttccaatc atatcgtaga agtatgctac cgcaatacca actagtgaga tcccaatggt
    33121 tgacattcct ccatacacag aacaaatgaa tccaatcaac aagaataccc acatattttt
    33181 cttgagcatc atatttaaaa gcataccaaa accaattgaa ggtagtaaag cacctgcaga
    33241 gttaagtccc tgcataacga ttggtggaac cttagcaaac aagtctgcca catattcccc
    33301 tccaagcata atagctagga aaattggtac aattttaaat aaagtgatta aaaccaaact
    33361 tgaataatga taaaaaccga tctttgaata atctccgttt ttagcatcat tatcagcttt
    33421 tttcacaaaa taaacatcta aagtttttgc aagaacatcc aactgttgag tagcaactgc
    33481 aattggaact gctatagcga taccagcagt ttctccttga ccagacaaaa taccaaatgc
    33541 agtaccaata atcgcacctg aaatagtatc tggtggagtg taacctccaa tacctgttac
    33601 accgagccaa gttaattcaa gagctgaacc aataagaaca ccttgggtga aatctcctaa
    33661 gactaagcca accattgcac ttgtaactaa cggacggtga atcataaata acggtccatt
    33721 atagtcaata gtggcaataa tcccaactaa tgtcaccagt aatgcttgtg tgaatagcat
    33781 atactgtacc tccttaaatt atttttataa aaatttttcc aacattgtaa ctttatcatt
    33841 aggaaccatt tgaatttcaa ctctcgttcc cttatcaact attttcttaa aataatattt
    33901 gtcttcttca cctagagcta cacctcccgt taccttttca ttttcctccg ttttactcat
    33961 ctgtcctaca ttgaggtact ccaattttaa atttccttca atagaatcat acacatcttt
    34021 tggatttgta tatatcagca ttgttctctt ttttattggc acagagttta aaacttccac
    34081 aaaccgtttt acactaaaga aaacaatttt taaacctacc ggtgcagaaa tctttaaaat
    34141 agattgtcgt gttttatctt ctgagatgcg atcattaaca atgataactt gctcaatatc
    34201 atactttttt agccacgtag tgacaacttg accatgtacc agacggtcat caatacgaac
    34261 aaactctata ggcataaatc ctcttcctcc tctacgttaa gttgttgttt aacattaaac
    34321 aaactatttt gagcattttg aacaatttct tctaaattga tttttgaatc ataacttgat
    34381 attaattcca ctaggagagg gatattaaac cctgttacaa tatcaactga atccaaattt
    34441 aaaaaccgtg acaaagccac attattagga cttcctccaa tcaagtcagt caaaacgata
    34501 acctcttgat ttgagtctaa cagttcattt acttgatttt taaaataatg ttcaaactct
    34561 acaatattct ctccaggcat caaacctaat gtcctaactc tatcatttgt tgtctcacca
    34621 acaaacattt ctgcggtcat gagagctccg ctagcaaaat taccatgact ggcaactaaa
    34681 attcctctat taaacatttt ctctttcaac aactactcct ttcttaagga taatattagc
    34741 ataaagtgaa gtttctcctg tagcaacaat agcataagct ttcttactac gttcataaaa
    34801 gtcttctctt ctaagataag taatcgtttt aagatctgta ccatgacctt caatcatctg
    34861 tctataggta ccccatatct taggaatatc atcacccgaa acaacgttca taaactgaat
    34921 tgaactatcg acgtaactat ctaatggcat taaatacaga atggaatcta ataattctgg
    34981 aatatttaca ccatcacaac gaattagctt atttgcacat gaggcagaag gataattcgc
    35041 gtcagctaat actatttcat ctccatgtcc catttccatt aaagtcttca ataaatctgg
    35101 agaaatattt ttcggtatat gttttaacat taatatcctc cctattttct ctgaccgtat
    35161 gttttaaatt tttctgccat caattccatc tcctcatcag gaagaactac tggctctcca
    35221 aaattcttag ctaaacaata aatttttgca caatattcaa cttcttcaac aatattaaat
    35281 gcattcaata aattttgtgc acctgctaaa attccatgat tcgctagtaa aactgctcta
    35341 cgaccttcca ttgctttagc tgcattcaca gccaattctt tcgtgccata tgttgcatac
    35401 tcagctaccc gaacatcttt ccctgccact gcaatcatat aatgactcgc tggaagtggt
    35461 tctctgagac aagctaatac tgttgcataa gttgtatgag catggataat tgcatcgata
    35521 tcatcacgag tttgatattg aatcaaatgc atataccatt cgctagatgg caagcgttct
    35581 ccctctacaa catttccatt aatatccatc actacaatat cggattcttt gatttcaaag
    35641 aaatcaatac ccgacggggt aattgccatc aattgttttt cacgatcgaa aacgctgaga
    35701 ttcccacctg ttcctttcgt caaatctgtt tctactagct tcttaccata tttaattaat
    35761 tcttgtttta catctgacat ccttgtcctc ctcatatcaa aacactaaat atttttcaat
    35821 tcaccaatta tccccccttc ctgcacaaaa gctaagaagg gggagggagg caaatttaca
    35881 aactctcaat ctttttaatt cttttgggag taataactct ctaattgtag aaactcctca
    35941 ataacatggt gagcctcttc catccctttt aattgtccca tagctatgag ctgcacaaca
    36001 atattcccca cagctgtacc ctcagtcaaa cctgtaagaa cctctttacc agttctatca
    36061 gcaatcattt ggttaaagta actggctcta gcacctcctc caatcacata tatcctctta
    36121 taaaccttat gagttagttc ttctagtaac tctatcgctt tcctatacgt ttcagctagg
    36181 ctttcataaa caatcttaaa tagttgtcca tctgtccact ctctagtttc atgatgataa
    36241 actagatatt ctgtcaaagt cttgtgcata tcagattctg ttgcaaattc agttgattca
    36301 gtatcaatca gaggaagatt ttctttttct ttctccacca ttgtcctaat atcatcaaaa
    36361 gaataggctt tccctcttcg ttcaaatgaa cgtcttagtt cctctatgat ccacaaccct
    36421 gtacaattct tcagaaatgt aatcactcca tctttaccga cttcatttgt aaatccataa
    36481 ctgaaggatt cggtagtaag aatcggtgaa gtaagttcca ctccaaccaa agaccaagta
    36541 cctgatgaaa taaataaact accttctgtc ttaggtactg agacaatcgc gcttgctgta
    36601 tcatgactac aaacattcac aacaggaata tcgcctaaac catactcctc ttttatcctt
    36661 ccaagaacat ttccctctga aacaatttca ggaagtaaag ttgaatccaa ttcaaatagt
    36721 tttaagatat tctgattcca attttgactc ctaggatcaa ataattgagt tgttgaagca
    36781 atgctttttt ctgtagcaaa cttacctgtc aagagataat taaacaaatc tggcattaaa
    36841 agaatcttat tggtcttata gaaagagtca ggagattctt gacgtgcctt aaagagttga
    36901 aacaaggtat ttatctccat aatctgattt cctgtctctg aatacagttt ttctaattca
    36961 gtcatttcag atatttcctt taacactccc tttgttcttt catcacgata atgaacaggt
    37021 tgtgataaca gcttaccttc attatcaatc agtccaaaat caactcccca tgtgtcaata
    37081 ccgatagata aaatcttgta actagtatta gccaagcgga tactttcaag aattttagct
    37141 agtagaaagt caacatccca agataaatgc ccttttactc taataggtag attagaaaag
    37201 cgatttattt cttccattac tagtttattt tcagaaaggt aaccaacgat tgctcttcca
    37261 gaagtcgcac ctaaatctat tgctaaaacc gcttccattt ttcttctctc ttcgtccttg
    37321 attaacttta ttataatccc cacgttttat tttttcaata tgtgaacgct tacttgaata
    37381 atgttcaaat gttaacccaa tattcataaa aataattcac attcctccaa tttgtgctat
    37441 aatatagttg aaatgataaa ttaggaggag cttatgataa aagatgaacg tgtacttgaa
    37501 ttgattgaaa tcatcaaaaa gaaaaaaaga attgccgtaa aagagctggc agaaatcact
    37561 ttctccagca caagtacctt acgtcgtgat ttaattttct tagaaaatca aggtcttatc
    37621 aaaagaaagc acggatacgt gaccctgtcc tctatgaaca caattgaact ttctcatcaa
    37681 atacgggaag gagaaagtac taggcaaaaa agactaatcg ctagtctcgc taaagacttt
    37741 attcggtctg gtatgtgtat ctatctagat tctagtacta ctgtctacga actttgtccc
    37801 tatctttctg aacttgataa tttgattatt tttacaaatg gtttacatac tgcacaaacc
    37861 ctatctgaaa ctgttaaaga tagctccaaa atctttatca catctggcga ggtcaaacat
    37921 caatcctgtt ccgtggtcaa ctatgataag gaaaattctt tattagatca ttttaatatc
    37981 gatttagcat tttgttcagc aagaggtatt gatgaccaat atgtttatga agcttctctc
    38041 agccaagcta tttcaaaaaa gaatattatt gacaaagccc atgaaaccat cttactgatt
    38101 gatagttcta aattttacaa gactggattt tttaaaatta atcccctatc caaatacaca
    38161 acctttattt ctgacacctt gccagaccaa aaattattag acgcagtcga attatttgat
    38221 ggagaatggg tttctgatat tcaataaaaa tcaaatagga agctagtctc agcttgctca
    38281 cagtacagat ttgaaaactg atgaagtcaa ggcccccatg gacacggcaa gacgaagctg
    38341 acatgatgtg aagagatttt cgaagagtat cgttctgtct gctgactgat ttacaaatat
    38401 tcaccacatg acattatttt cttagcaacc ctaaaaacag aggctggaca aaaactcaat
    38461 ttcaggagaa atggggcaaa tattcccaca ataaaacgca tagtatcaag tttttgcaca
    38521 cctgatatta tgcgtttttc tgattttaaa gactttgtcg cctagaccct atatttcaag
    38581 aattaagtga ccttgatgat ctaaatgtat tgtggtatac tatttttgtc atcggttacc
    38641 gattacgttc ctatgggttc gtgagaggag gtgaaactaa tgagccttat catagagctc
    38701 gctcttacta ttatagcgga tgttatagct ggaattatct tgtatttcgt ctgcagatgg
    38761 ctagatagta aggagtagac cgactgacta gcctataaac acccgttaaa tcgctaagat
    38821 acgtcaaaaa agcccttaac tacggccata gttaggggct ttggtgttct aatgaacctt
    38881 atcaattaac tacattttag catataagtc ctaatatttc aagcattaag caatgttgat
    38941 gatctaaatt taatgtgata tactattttt gtcatcggtt accgattacg ttccttacgg
    39001 ttcgtgagag gaggtgaaac taatgagcct tataccagag cttgctctta ctattatagc
    39061 agatgttata gctggaatta tcttgtattt cgtctgcaaa tggctagatg gtaagaagta
    39121 gaccgactga ctagcctata aacacccgtt aaatcgctaa gatacgtcaa aaaagccctt
    39181 aactatggca ctagttaggg gctttggtgt tctaatgaac cttatacact aactacattc
    39241 tagcatataa gcccagatat ttcaagagtt ttatttattt tttcaggttc ccttagttct
    39301 gaaaggtcta taatgaagtt agccatctag tatcaaaaaa ccgactagct cttatgaact
    39361 agtcgatttc tcatcaatgc gccaacattt cttgagcgat ttcttggcca gataggttat
    39421 ctgggtagta ggttggccag ttgtccattt cttcaaagag ggcttcttgg cttgtgcctc
    39481 caaagaagat atggaaatgt tctgccttaa ctggggcgat attgtggtca ctaaactgaa
    39541 catacttgaa ttgtccagcg tcagcatctg tggcttcaaa gaggaaacgc acgccacgat
    39601 tgcctttctt gtaagtcaaa attttcttac cgacatactt gtaagtatat ttcttgcttt
    39661 gtccaccttg aacaaattcc atagtattat cagtaatgtt aatcttagtc acatctgtct
    39721 gatagccttt tgtatagtaa gccttgtact cagcctgggt catcttacca gtcaacttag
    39781 ccttgtagtc aaagacttgg tcaaacgtgc cgtcttcaag gaaaggataa actgattgcc
    39841 agttacctgc atagtcactc aaggtgcggt ccttgacagc tgcatcctcg aagtaaccat
    39901 tttggactgt cttggtatcc tctgcctttt caggctcgat cgctgggcct tcttggtctg
    39961 ttgtttgttt caaagccttg aggtttttct ccatgataga gatgtaattt tctccagcct
    40021 tggtgtcctc ttctgtcaga ctttctaaag gattgaggac atcagttttg acacctgctt
    40081 cttttgaaag tgtgttagca agggcttgtg aggcattttc ttcaaaatag atataggcga
    40141 ttttattttt cttgacatac tctgtcaatt ctgccaagcg agcagctgat ggctctgcat
    40201 ctggagaaag tcctgagatt gcgacttgtt tgagtccata gtccaaggca agatagttaa
    40261 aggctgcgtg ttgagtcaca aagctctttt gttttgcttg agacaagcct tctgcgtaag
    40321 ccttatccaa ggcttgcaat ttttcgatat aggcagctgc attcttctca aaggtctctt
    40381 ttttatcagg ataatctgct gacaagctgt cgcggatgtg ctctactagt ttaatggcac
    40441 gaactggtga taaccaaaca tgggggtcaa actcatggtg atgaccttct tctccatggt
    40501 catggtctcc ctcttcttcc tcgccacctg gcaagagcaa catatcgcct gtcgccttga
    40561 tggttttcac ttttttctta tccaaggtat ctagcaattt aggtacccat gtttccatgt
    40621 tttcattttc ataaacgaag gtatctgcat cttggatttt ggcaactgcc ttggcagatg
    40681 gttcgtattc atgaggttct gtcccagcac cgattaggag ttctacatta gccgtatctc
    40741 ctgcgacttg cttggtaaat tcatagacag ggtaaaaggt tgtcacgata ttgagtttac
    40801 catctgcctg tttttgattg gaacaagcca ctaaaaacaa ggcacataga ctggctagta
    40861 ataagctaat ttttttcacg ttcgtctcct atttgataaa acgtcttact aaactgatta
    40921 gtataaagac agttacaaaa ataatggtaa tacttgcact tgcaggtgtt tctgcatagt
    40981 aggaaatgta aagtcctgct accattccca aaaagccaat cgcactggca agcagcataa
    41041 ccgatttaaa gtttttcccc agacgcaggg caatactagc tggcaagacc ataatggtcg
    41101 ataccagaag agctcctgct gcaggaatca taagggcaat agccacccct gtcaccatgt
    41161 taaaaagaat ggacatggta cgaactggca agccatccac aaaggccgta tcttcgtcaa
    41221 aagttaagat atacatagga cgaagaaaga gaaaggtcaa aatcaaaaca accgccgcaa
    41281 tgacaaagag ggaaatgacc tgttcttcac tgatagtcac gatcgaacca aagagatatt
    41341 ggtccaaact cattgaactc gagcttttac ccttgctcat gacaatcaga gaaacagcca
    41401 aacctgttga catgaggata gctgtcccga tttccataaa gctcttgtaa accgtacgga
    41461 gatactccag aaagaccgcc gcaatcaaga caatggcaat agtagaaaca gttggagaaa
    41521 tccccaaaac cagaccaaag gctacacctg aaagtgagac gtggctaagg gtatcactca
    41581 tcaaactctg acgacgcaag atgaggaagg ttcccaatac cggtgagaaa agactcatag
    41641 caataaccgc caaaaaggcg cgttgtataa agtcataaga taataaacta agcatggccc
    41701 acctcctgcc cattctcatg aacgttgaaa caacgccatg gcgagtcttg gttacggact
    41761 agatgaatat tgcgatccgc ataatcctta acttcttcag ggtcatgggt aatcatcaaa
    41821 acagccttgc catgatgatg ggcgctgtgg tgcatgagtt cgtaaaattc atttttactt
    41881 cctgcatcca tccccgttgt cggctcgtct aggataaaca catcagggtc agaagcaaac
    41941 atacgcgcaa tcaccgctcg ctgcttttgt cccccagata gagaccccaa gcgtttgtct
    42001 cgatgttccc acatgccaac tgagtccaga ctggccttga tatgctcctc atcatgagca
    42061 ttcaaacgac ggaaccagcc ttttctcgga tagcgacccg acttgacaaa ttcatagacc
    42121 gtacttggaa aaccagcatt aaaactggca atttgttgag gaagataggc tattctcaat
    42181 ttcttacctt gcgtatttgt ctttgaaata gccacctttc caatgcgtgg ttgcagaatt
    42241 ccaagactgg ccttgatgag cgtcgtctta gccgctccat tttccccagt caaggtaaca
    42301 aattccccac tatcaacact ataattgata tgttcaagaa caggctcctt atcataatag
    42361 aaggacaaat cctctaccgt aatatatctc attatttgat ttctcctact aaagcagtca
    42421 aaaaccgctg aatcactttt tgttcatttg gagtaaactg agtcgccact tgttcatagg
    42481 ttaaaagtgt atgctcatgg tgatggtggt gctcctcagc gattggacga gccaagtcag
    42541 tcaactgata aaaaatcaca cgcgcatctt tagaatcttt agatgtttcc aacatccctt
    42601 ccttgaccaa agacttaatg gccttggtaa ctgccgcctg actgacattg agacgacggg
    42661 ccaattctga atttgttaaa gattcctctg acaagagcat aaggatatgc tcctgagtat
    42721 tggtcagggc cacctcgcta gtgcaatgac ctattaggat ttcatgctga ttttccgcct
    42781 gcaaaatcac ctcattcaaa aaagcattga tatcctttgc tagctgtctc atatctgact
    42841 cctttccttt tagacttctc ttttttaaga gaaaaatact attctttgac attttgttta
    42901 ccagttaatt atatcacaag caaaaaaaga gtcaagaaaa aacgtgaaaa ctagtttcat
    42961 tcttgaactc ttctatatta tattatctat tgaaattctt tgacatctcc atcataagtc
    43021 gcccaatctt tgctgaaaaa gcgctcattc agatggtaag tcggagctgg tgtgggattg
    43081 gataggaaag gatcaactgc cttgtcaaaa gccaaccaac ccaaccaacc aaggtgaatg
    43141 gtgtccttca taaagaaagg ctccccaccg tccttagaaa aatctgctat attggtaaaa
    43201 ccttgacttt ctaactggta gcgaatcttc tgcaccgttt gttggtacat atcctctcgt
    43261 agaccagcat agtccatcca ttttttatta acaggtggaa tgataaaaat cgggtttacc
    43321 ttagatttag aaaactgtgt taaaaccaac tgcaagtcat tatactctgg cgacttgaga
    43381 taggtaaagc ttttctgaga atcctttaat ttcttcaaat ccttcttgat ctgctcatta
    43441 tagaaataat tttccattcc catctcatta ttggaagtat ttttttcagc atctgctttg
    43501 acaacatctt ctattgcttg ataagaaaac tggtctggca agatttttaa atacttagct
    43561 acatgcttat cgtagttaac atagcctcta accgaaaact gaccaaaaaa ggaggcttgg
    43621 cgttcattaa aacgagccaa taattcaatc atttcattgt ctgctgtcga caattcttct
    43681 ttacttgcca acttctgaac caggtccttc atagctacgt ttgggaactg ttgcagtaag
    43741 cgagtcgctg catattgact agcctgatcc ccagattgat gtttcagaaa actagtcaac
    43801 tggtctccat taaaatactg ctggaaggct gctggatcat agccattttt actgaaccac
    43861 tgaggtgaga taacatacac aacttgttta ttctccagct gtggtaacat ctgttgcatt
    43921 ccaaaatatt ggttaagcga tgcagctccc ccctgtccta aaagataagg acggtaggaa
    43981 cgattgtatt tctcagctaa taccgcagga tgagcaccgt caaaacgaag ccattcacta
    44041 gagccaaaga agggaacaaa acgcacattt ggatcagata gtgctctgac tttttgactt
    44101 cgctccttaa aactatcgat agtagtagcc actgctgaac gcttttcagc tcctagatta
    44161 tgatgcatct cagtaggata aaagaaaatg agcagaaaaa ccaacaaacc agcgatcaag
    44221 accggtccga agatcatcca taagcgttta agcattttgt agctccacaa taccagctat
    44281 gattttatta gctgtattcc agtcgtcacg accaaactct gttacaggga cacgaatgtc
    44341 aaaacggttc tcaatctcca caatcaactc aaccgttccc atactatcca agacacctgc
    44401 atcaaaaaga tcttcatcca tcatgtcaga aacatcttcc ataaacaact catcaataat
    44461 ttcaataact tctgatttga tatccatatt ttatttcctt ttatttttta aaccatagat
    44521 tattcaagaa tccagaaaag attaagaatg acaacatgac aacatggaaa gtgacaacca
    44581 tgccaagcaa ctgaatccag cgattctcag gtagggcagc cttccctgct tttttccgtt
    44641 ccttattgag cgtttttttc ttgcgaaccc aggcatcatt gatgaccaag cctagtccat
    44701 gaaagagtcc ataggcgata tagtaccagg tcacaccatg ccaaaatccc ataatcagca
    44761 tatttacaat gtaggccatg cttgaggtta cattacgatt tttaaagact ttctttctgg
    44821 ttaacaccat caccattcgc ataaagacaa agtcacggaa ccagaaggac agactcatat
    44881 gccagcgatt ccaaaactcc tttaaatccc ttgataaaaa gggcttgtta aagttgatag
    44941 ggctacggat tcccatcaag tttgagatgg ccaaagcaaa catagaataa cctgcaaagt
    45001 caaagaagag ctccagacca aaagtataca taactgccaa ggcatagaga ttaaagaagc
    45061 cacctgactg caaggctaaa ttcttcagag gaggtagtaa ggtctctcct aaaacatgag
    45121 ctaggataaa cttatacaaa aagccccaca tgatatagcg gacagattca tccagcatat
    45181 ccatcaactc atctcgctca ggaatagcct gataattttc attaaatcgc ttaaagcgat
    45241 cgattggacc actcgagaaa gttggcatga agagaaggaa acggaggaat tcccagaggg
    45301 taaaatcctt aatcactcca tctctcagct cgatgataat cccaaccgaa cgaaaggtca
    45361 ggtaagaaat tcccaagaac ccaagcaaag actgcgttcc attgatagct ggttgcacct
    45421 tgacaaagat aatcggaagt agggacagaa aactaactaa gtagaagacc cacttgccat
    45481 ccttgctttt tcgataatgc ttgtagaaaa gcaggagcaa tatttcccag caaaggtaaa
    45541 tacccaaggc agctagttga ttggtctttc cacccaccaa catggtgaca ataaagaaga
    45601 gacttaccaa cacttcatac caggcaaagc gtttcttgaa aaagaggcct ataaagatgg
    45661 gcaaggttgc agcaatcaca taaacaaaat actgaggatt gccatatggc tctaaatgag
    45721 gaagctgttg aaaaaactcc atcatctctt attcacctcg ttaatcaatc ctttgatgtc
    45781 aatctttcca tttggagtta gtggcaaact gtctcggtaa aggaatttag atggcatcat
    45841 gtaggacatc atgatgtctg tcaggtcttc cttgatggcc ttggtaatat cgatatctcg
    45901 ctcaaactgc tcacgaacac cgtcttttaa gatgacataa gccaatagat tttgtacctt
    45961 gtggtccttg ttatagcgcg gtactgcgac agcagattcg ataaagcgag acttgttgag
    46021 gttttgagag acatcttcta actcaatgcg gtaaccgtta aacttaatct ggaagtccat
    46081 gcgtccgccg tagagaagca agccctcatc tgtcatggtt cccacatcgc ctgtgtgata
    46141 ggctggcaga ccttcaaact caaagaaggc ttctgctgtt ttttcaggat ttttcatata
    46201 accttttgaa acagctggcc cagaaacaat gatttctccc tgctcaccat ttggcagttt
    46261 atttccttcc tcgtcaatga taaaggttgg agaatcagcc ttggtatagc cgattggtag
    46321 gcgtttgaga gtcgctaaca tctcgtctgt cacggcaact gctgacagag ctactgtcgc
    46381 ttctgttggg ccgtaagcat tgatgatacg ggcatttggg aaacgctcgc gcagtttttg
    46441 agctgttttg accgtcaatt cttcaccatc aaagtagaaa tgcgtgattc cagacatttt
    46501 ctcactgttg aagtattcag acaacatggc catatctgca aaggatggtg ttgatgtcca
    46561 gatagcgatt ggcaatgaaa agatagccgc aaagagttgc ttaaagtcct gagtgatgac
    46621 tgaaggaaga gtgaaaagcg taccaccaag tgccaaggtc ggtgcccaat acatgacaga
    46681 caagtcaaaa gaataaggtg gctgtgccag catttgcgga cgactcggtg tcgcaaattc
    46741 cttatccgta atcatccagt ttgtaaagct gaggagatta tcatgtgaaa tctgcactcc
    46801 cttaggctta ccagtcgtac cagaagtaaa gataatgtag taattatcat ctcccttgac
    46861 tggatgcgtg atttcatagt tgttcccttg ggcaaaggct tcttgaacct gagctagatt
    46921 tatcattggt gtagaaacct gctccaaggg aaaggctgaa atggcaataa tcaagcttgg
    46981 ctctgctact tctaaaatag ctgaaactcg ctccaaggcc gaatggctat caattggaat
    47041 gtaggcatga cctgacttag tcagcgctac aaaggttgcc aacatttcat attcttggcc
    47101 accaaaaaca accacaggag acttctcagg caagcctagt tggtcaatga ctgcagccaa
    47161 actatccgaa tcagccttta aatcgccata agtgtgttcc tgccccaaaa cattatagac
    47221 aggatagcta ggctgtgtct gagcaaaatg ctcaatggtt tcaatcatat ctgctattgg
    47281 tttatttgac acaataggga ttctccttca agttaaaatt cattatagat aaagcttcct
    47341 tgaccctgac caagatagct aaagaagtaa agcagcccta gaaagataag aaaatacaag
    47401 gctgtccgac caagaaagag gtacaattct tttctctgtt tcatcaagaa aaaccattca
    47461 tttctgtaat ttttcgctaa aataagagtg attcttacta gcttattttt ctaccattgt
    47521 accactttat atagtatctt ttcaattgtt taccgtatgt ttccaataga tttcagctta
    47581 ttttaaggat tatacagttt ttctatgtat attttcaaat agagtgatcc tgcttcaaaa
    47641 ctccatttca ggagacaatg aagtaaatct tcccataata aaacacacaa tatcaagttt
    47701 tttcaacacc tgatactatg cgcttttctg atttttaaag actttttaac cactctctca
    47761 tttaaaataa tctcgtctga tataaattaa aatagcttct atcatcagac aaatggctga
    47821 tagccaaaaa ctgatgctaa taccaaaact ctcagtaata tagctcatta gcaaaacaaa
    47881 tactgaaaat gctaatgtag aaatcacttc aagaacggaa tagacattaa ctaaatgatt
    47941 ttcctctact gtttcctgaa gaaatacact ttcaggaact tcttttagtt gcgataacat
    48001 accaactaaa gctgaaaata ataaaaacat ctgtgcgttt ggaaaatata gaatagtcag
    48061 tgtcactatt gccatagcta caagaggaaa aagaatactt tcccatttag cagcaaggaa
    48121 cttttcagat agcctaaaag caattaagcc actaattata ataccaatag agtatgctgt
    48181 attagaatat ccccagtaac tttccgtttt atttaataac tccgttacaa aaacaagtat
    48241 aatggaagaa acccaaatcg tatttgaaaa aatttccaat aaatttgctg atacaaaaag
    48301 tcttaatcta ggatttctag caactaactt ccaacctttg agcaaaattt caagattagt
    48361 ttctgactct aacacctcca cttcagcgtt aggaagaaat aacatcagaa agctagaaat
    48421 gatatacaag actaaaatga taaacgtggt aggtaacaga ccaattgttg caaataagag
    48481 tccacctaat ccccaaccta tcaattgaac agcttcacca gtcattgata aggctgaatt
    48541 agccttaccc aaatcggtcg catagcgtgg cacaatagca taggaaacgg gtgctgcaaa
    48601 accatctagt atggaaattg caacaacaaa tagataggtc accaaaggcg ctacggattg
    48661 cattacggta aacattccta ccagtatcgc caataatata gtctttccaa attgagataa
    48721 agataaaacc ctatttagcg ctaacctttt agtaaccaac ggaactaaaa gactcgcaac
    48781 aaaagaggat attcctatta agataggaac tagtgatgtg gcaattactg attttgaaat
    48841 aatgtatatg ttagcaatga ttgttactct aaagaaaata tctgctaaat ttgcaaataa
    48901 ttgagagact aacaacttga caaatgaatt agacatgtag cgctccccct ttagttacaa
    48961 actttggaat taaatttgat ttttaatatt ttagcataaa atagcagaaa acaaaagtga
    49021 ggttttttac atgaaaaaac aaaaactatt gcctttatta ttcctaattt taggaggaat
    49081 tatgattatc gttgttggct agtactaaga agttagttag ttagtagaat aattacatct
    49141 tcaatcgaaa aagagactgg gaaaaagtct taaaaatcag aaaaacgctc aaatcctttg
    49201 gcgctctaag cttttctaat gatagatttt agatagtcaa aaaaatatct gaaaagttcc
    49261 cagatcgtcg tctcagcatc aaaaatacgt gaaatttgca taattaaaat aaatttcagg
    49321 ggagttaatc gagtagggga taatctctag cccctctcac accaccgtac atgccgttcg
    49381 gcatacggcg gttcaactaa cttttaacgc atgtcgttca aggtaataat ccaaacacga
    49441 aaccagtcca cgtttttcaa ggactggttt tgatatagca cgtttaagta ccgacttctg
    49501 agctact
//
LOCUS       DAVLMQ010000010        48156 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000010 DAVLMQ010000000
VERSION     DAVLMQ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 48156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.010"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(7..303)
                     /locus_tag="VXF95_000703"
     CDS             complement(7..303)
                     /locus_tag="VXF95_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081286.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VXF95_000704"
     CDS             complement(287..2446)
                     /gene="pfbA"
                     /locus_tag="VXF95_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HEV1081287.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNN
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHAIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SFIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3577..4803)
                     /locus_tag="VXF95_000705"
     CDS             complement(3577..4803)
                     /locus_tag="VXF95_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HEV1081288.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVLEVGPGDEVIVPAMTYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWRANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVHYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4846..5538)
                     /locus_tag="VXF95_000706"
     CDS             complement(4846..5538)
                     /locus_tag="VXF95_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1081289.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGSLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSPEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMHYNLAYLREFSFFGDI
                     KIMFQTVFEVLK"
     gene            complement(5711..7462)
                     /locus_tag="VXF95_000707"
     CDS             complement(5711..7462)
                     /locus_tag="VXF95_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081290.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGFSIG
                     ITVGTMYAFIQYINRLFDPLIEVTQNFSTLQTAMVSAGRVFALIDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQETSDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGLSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMADTL"
     gene            complement(7452..9197)
                     /locus_tag="VXF95_000708"
     CDS             complement(7452..9197)
                     /locus_tag="VXF95_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1081291.1"
                     /translation="MSIIQKLWWFFKLEKRRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSSAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLVFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     CLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTDLRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSAVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILDPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9403..9699)
                     /locus_tag="VXF95_000709"
     CDS             complement(9403..9699)
                     /locus_tag="VXF95_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HEV1081292.1"
                     /translation="MSASDVALKLRGQGIFQMKQVKRAVQEQNGQLIVVQMGDENSKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9852..10307)
                     /locus_tag="VXF95_000710"
                     /pseudo
     CDS             complement(9852..10307)
                     /locus_tag="VXF95_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10440..11267
                     /gene="xth"
                     /locus_tag="VXF95_000711"
     CDS             10440..11267
                     /gene="xth"
                     /locus_tag="VXF95_000711"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HEV1081293.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAENADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTVTFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDVKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11279..11422
                     /locus_tag="VXF95_000712"
     CDS             11279..11422
                     /locus_tag="VXF95_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1081294.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCDLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11422..11661
                     /locus_tag="VXF95_000713"
     CDS             11422..11661
                     /locus_tag="VXF95_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HEV1081295.1"
                     /translation="MLEEGTKDQLAELTYLFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDHYIYPHEFAVLDPDSYFLRFSE"
     regulatory      12045..12140
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12540..13121
                     /locus_tag="VXF95_000714"
     CDS             12540..13121
                     /locus_tag="VXF95_000714"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HEV1081296.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGKVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13121..14383
                     /locus_tag="VXF95_000715"
     CDS             13121..14383
                     /locus_tag="VXF95_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HEV1081297.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIAMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14470..15336)
                     /locus_tag="VXF95_000716"
     CDS             complement(14470..15336)
                     /locus_tag="VXF95_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-2 restriction enzyme DpnII"
                     /protein_id="HEV1081298.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEETKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15323..16093)
                     /locus_tag="VXF95_000717"
     CDS             complement(15323..16093)
                     /locus_tag="VXF95_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1081299.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16119..16973)
                     /locus_tag="VXF95_000718"
     CDS             complement(16119..16973)
                     /locus_tag="VXF95_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HEV1081300.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELIPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17130..17534)
                     /locus_tag="VXF95_000719"
     CDS             complement(17130..17534)
                     /locus_tag="VXF95_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HEV1081301.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGRRSEDRQVRI"
     gene            complement(17604..19085)
                     /locus_tag="VXF95_000720"
     CDS             complement(17604..19085)
                     /locus_tag="VXF95_000720"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HEV1081302.1"
                     /translation="MILVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSQKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAAAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARTNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQAAFMRFVEQVGISLD"
     gene            complement(19104..20282)
                     /locus_tag="VXF95_000721"
     CDS             complement(19104..20282)
                     /locus_tag="VXF95_000721"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HEV1081303.1"
                     /translation="MAQHLTTEVLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAVDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEAFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20447..21454
                     /gene="galR"
                     /locus_tag="VXF95_000722"
     CDS             20447..21454
                     /gene="galR"
                     /locus_tag="VXF95_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HEV1081304.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFKNYSQARGIYHDELVFQGR
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21500..22537)
                     /locus_tag="VXF95_000723"
     CDS             complement(21500..22537)
                     /locus_tag="VXF95_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1081305.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAVTTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLQSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22538..22891)
                     /locus_tag="VXF95_000724"
     CDS             complement(22538..22891)
                     /locus_tag="VXF95_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HEV1081306.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23135..24025)
                     /locus_tag="VXF95_000725"
     CDS             complement(23135..24025)
                     /locus_tag="VXF95_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HEV1081307.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALPRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     VSLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24158..24694
                     /locus_tag="VXF95_000726"
     CDS             24158..24694
                     /locus_tag="VXF95_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1081308.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIINLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24861..25667)
                     /locus_tag="VXF95_000727"
     CDS             complement(24861..25667)
                     /locus_tag="VXF95_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HEV1081309.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLLN"
     gene            complement(26012..27532)
                     /locus_tag="VXF95_000728"
     CDS             complement(26012..27532)
                     /locus_tag="VXF95_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HEV1081310.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALMAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
     gene            complement(27525..28253)
                     /locus_tag="VXF95_000729"
     CDS             complement(27525..28253)
                     /locus_tag="VXF95_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081311.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            complement(28268..29032)
                     /locus_tag="VXF95_000730"
     CDS             complement(28268..29032)
                     /locus_tag="VXF95_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HEV1081312.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            complement(29036..29479)
                     /locus_tag="VXF95_000731"
     CDS             complement(29036..29479)
                     /locus_tag="VXF95_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1081313.1"
                     /translation="MKDSHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            complement(30161..30457)
                     /locus_tag="VXF95_000732"
     CDS             complement(30161..30457)
                     /locus_tag="VXF95_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1081314.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETTKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            complement(30479..31543)
                     /gene="pepA"
                     /locus_tag="VXF95_000733"
     CDS             complement(30479..31543)
                     /gene="pepA"
                     /locus_tag="VXF95_000733"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HEV1081315.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKAEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            31943..32644
                     /locus_tag="VXF95_000734"
     CDS             31943..32644
                     /locus_tag="VXF95_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1081316.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYKVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLKENQIDAVLHYAGEIVVSESIENPSKYFTANVAGRNQV
                     LKVLSEVGTQKIMFSSTASLYGNNCIDKPATEDTLIDPVNPYTETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQNDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            32660..32770
                     /locus_tag="VXF95_000735"
     CDS             32660..32770
                     /locus_tag="VXF95_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="HEV1081317.1"
                     /translation="MNYLFQEDSSSQIFNLGTKKGYTIKEIFKTAEELLN"
     gene            33067..34026
                     /locus_tag="VXF95_000736"
     CDS             33067..34026
                     /locus_tag="VXF95_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081318.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSESLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKCYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            34016..34972
                     /locus_tag="VXF95_000737"
     CDS             34016..34972
                     /locus_tag="VXF95_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HEV1081319.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            34969..35721
                     /locus_tag="VXF95_000738"
     CDS             34969..35721
                     /locus_tag="VXF95_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081320.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGS
                     TDQIMQADLLSQLYEIPITLADINDKKICIYS"
     gene            35817..36782
                     /locus_tag="VXF95_000739"
     CDS             35817..36782
                     /locus_tag="VXF95_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1081321.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(37007..37249)
                     /gene="yidD"
                     /locus_tag="VXF95_000740"
     CDS             complement(37007..37249)
                     /gene="yidD"
                     /locus_tag="VXF95_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HEV1081322.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLARILRCHPWSKTGKDPVPDHFSLKRNQEGE"
     gene            complement(37249..37971)
                     /locus_tag="VXF95_000741"
     CDS             complement(37249..37971)
                     /locus_tag="VXF95_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1081323.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLTIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            complement(37958..38527)
                     /locus_tag="VXF95_000742"
     CDS             complement(37958..38527)
                     /locus_tag="VXF95_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HEV1081324.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            complement(38546..39274)
                     /locus_tag="VXF95_000743"
     CDS             complement(38546..39274)
                     /locus_tag="VXF95_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HEV1081325.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            complement(39274..40014)
                     /gene="xerD"
                     /locus_tag="VXF95_000744"
     CDS             complement(39274..40014)
                     /gene="xerD"
                     /locus_tag="VXF95_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HEV1081326.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLIIEMGLLPSEILVIKVADINLDFQVLRISKASQRRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            complement(40005..40466)
                     /locus_tag="VXF95_000745"
     CDS             complement(40005..40466)
                     /locus_tag="VXF95_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1081327.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDAEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            complement(40463..40984)
                     /locus_tag="VXF95_000746"
     CDS             complement(40463..40984)
                     /locus_tag="VXF95_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1081328.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWLEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            complement(40960..41931)
                     /locus_tag="VXF95_000747"
     CDS             complement(40960..41931)
                     /locus_tag="VXF95_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HEV1081329.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            complement(41928..42722)
                     /gene="racE"
                     /locus_tag="VXF95_000748"
     CDS             complement(41928..42722)
                     /gene="racE"
                     /locus_tag="VXF95_000748"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HEV1081330.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            complement(42929..43177)
                     /locus_tag="VXF95_000749"
     CDS             complement(42929..43177)
                     /locus_tag="VXF95_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HEV1081331.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            complement(43433..45058)
                     /gene="treC"
                     /locus_tag="VXF95_000750"
     CDS             complement(43433..45058)
                     /gene="treC"
                     /locus_tag="VXF95_000750"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HEV1081332.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIEKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCVGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWTPFGDTGKYYLHLFDETQA
                     DLNWRNSNVRKELFKVVNFWRDKGIKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQTLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            complement(45236..47203)
                     /gene="treP"
                     /locus_tag="VXF95_000751"
     CDS             complement(45236..47203)
                     /gene="treP"
                     /locus_tag="VXF95_000751"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HEV1081333.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFVYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            47388..48098
                     /gene="treR"
                     /locus_tag="VXF95_000752"
     CDS             47388..48098
                     /gene="treR"
                     /locus_tag="VXF95_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HEV1081334.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
BASE COUNT        14176 a        10914 c         8917 g        14149 t
ORIGIN      
        1 ctattattat ttcattttac tatactctgt taattcatat gagtttaaac cgatttcatc
       61 tttaacctcg agtaaagcag tttcaaatat ttgtttaaga gtttttgatt ctttacaatt
      121 aaccgacaaa ctttctgata aaatatgtac aacttctgag actgaataac ctatctcctc
      181 tttagaatta tataaatctg tagctccacc aataatccaa aaatactgat tttgtgaacc
      241 tacaatatcc tcattttcta cggaacttcc ttgtatcgaa caaattttat ttatctttac
      301 cataatactt caaccctttt agtgtcaaaa gtaaaccaat tcctgtcact gttaagaata
      361 gttccataat cttgttcgaa ccagtctttg gtaatttttg ttttacatct actatttctt
      421 tagatttatt aatatgattt tcagtttctc tgccatctcc aactatttta tagtttactt
      481 cttctgtctt attatcttgt ttattgtcga tcttgtcatt catttgtcta ttatctttac
      541 ttgagttaaa ctctccgttc ttctggttac tatcaattac attatttgaa ttagattgtt
      601 tttcctcttt gtttttttct ttttcgtttt tatcacttaa attatttgtt acaattttgt
      661 aaagcccatt ctccgttaca atattgaaat taccatcgct atcacgtata acaggttctt
      721 tcccatttgc attagatttg atgaatgata tatacttacc ggataaatta taaaattggt
      781 tatttaaaac ggttatttta ccctttgaat cctcaataac aattccttct ttaccaccga
      841 atatactatt ctctgagact actaaattat cactaactcg taataattca atatttggtt
      901 gttctgtttc cttagaatta ttattaatta cattttttgt tacagtaata tctgatactt
      961 ttcctaaata ttctgcacta tcttttgcaa ctcgtatcgc ttttgtttta ggatcggcaa
     1021 tattaaatat attttcggcg ataaccacct gtttatttaa atctaatagg tctttagtgt
     1081 ttttatagct ataagcattt actaaagctg ctccgttttc tcgataatgt acactctctc
     1141 ctttaacttt cttatcaaag cgatttcctt tgattaatac atcagtgaat cctgtaaaac
     1201 gtacacctgc atacatcatg ttatcaaaat gattatttaa aattttaata ttagaggggt
     1261 tctgtgttga caatgtttga tagtgtgtgc caattgctgt tactaattcc ccagatttat
     1321 cacttttgcc aaaataggaa ttttgaatag tcacattttc agattttttc ccatcatcat
     1381 tcaaggcata aggaaaacct tttctagtta atggttcaat ctgaatgctc tccttactta
     1441 tgatttgccc atccttcatc gttttgggta aggcttgccc aagaaaacga gaattatcaa
     1501 ctaatacatt tttcgaacct gcaatttgaa tagcatgccc ttgataacta tccttgaatg
     1561 ttacattttt tatagttacg ttatttgaat tcccaatagc aaatgcacct gaagaattta
     1621 taagtggtag attttttgct ttagttcctt cttcattcaa agcaccgttc atatcaatcg
     1681 taccaccaga ataactaata tcttctgttg ggccccattc tacttgcgca ccatcatccg
     1741 taaataaacc tgtcataaaa acaatggaag ggtgattctt aatatttata ccatttagaa
     1801 ttgtagcttt ctcattcaat tctaagtgtg tatgactttt taaaaaaaca atttctttta
     1861 ctaaataagt tccttcagga aaatatacat ttcctccacc tagcccttga gctgcagcat
     1921 ctattgcatc ttgaattgct tgtcgatcat catgaatccc atcacctact gcaccataat
     1981 cttttacact taaagcagta tcttcaaatt cttttttgat aattctgtca cttataacat
     2041 cttccttata actcttattt tcattagtag atgttactgt agattcaact gttctgttgt
     2101 ctaattgtga attggaacga atagtaccat tagagctgat attattaaca cttaacgaat
     2161 tatctaaacc attagtggtt gaattagagg caatcatttc agcagaacga ttctgattaa
     2221 cagttggtga attatctaaa tcattagtaa ttgcattaga agactctttt gtagccatcg
     2281 gtgaagaact agtaacaact tcatccgata aaataccttg gcttcccaaa attgaaattg
     2341 ccaatagtac cgagcaagtc cccaccttta atttacgaat actgaatacc tcattaggaa
     2401 caaaatattt catcagaacc tccaattttt ttactatttt taacaattga ttattacttt
     2461 tcttaaaata gatagaatga caccgctgtc attatcttta tcatatattt tccaaattga
     2521 attgtcaagg aataacacaa gaaaatatta aaatttatac tcttcggaaa tctcttcaaa
     2581 ctaggtcagt gccgccttgc cctaagtcta ggttactgac ttggtcagtt ctatagtaga
     2641 ctgaaactat aatagtacac ctctacttct aaaacattgt tagaaatcga tttgactgtc
     2701 ccgatcgatt tgtcctattc ttatttcctt ttactatatc tacaacctca aagcagggtt
     2761 ttgagctatc tatggccaac ttcctagttt gctctttagc cttccattca aaagtgatgc
     2821 tatctttctt agcttgaata taaaatatcc catttactat atttaaattt attgatatgt
     2881 tgtaaattat aaatgaaaga acaaatacct tgtcatacaa gcattcgcca gggatattta
     2941 catgaatatc gctcatatgg cggattgaaa ctaaaacact acaatatatt tcttaaatag
     3001 accttctata aaagctagat ttaacctcga taaaaataga tgcagtgctt ctaaaatact
     3061 ggaatagggc atataggtaa tagtagacaa gtgttttata gattgtctcg caggagatct
     3121 aatgatgtat agcaagcatc actaaacata tagaatattt gcattattat aatatcaaca
     3181 tgttataaat tctatcatgc aaaagaatga ctagaacatg aaagacaggc acaaaacttt
     3241 gaacaatatt ctgaaaacaa aaaaaagacg cgagtttcca caatctcact catggaaact
     3301 cacgtctttc aaaaaatagg gtgaattgaa aactagaaca agacactaga ttttctaaat
     3361 gatgtctagt aaggattcta aatgctacac caaattgctc acatcttatt tcaaaccacg
     3421 ggactcccac aagaaaggaa aatcctataa aaattctctc tctgaggaga aagaggcctc
     3481 aactacaggt gtaaactatt atcaattgaa aacaacagtt tttacactca attagacttt
     3541 ttagggacag gatcactttc gcttgactgt agtttgtcat ttttttgata aagttagcac
     3601 tttttcagaa actgttttga aagtctcaat gatatagtct acttcttcat cgcttaattt
     3661 agtatgaaga gggagggtaa tttcattctc aaagaaggca taggctttag gatagttcgt
     3721 catatcaaat ccaagattct tataggctgt caagagagga agcggtttgt agtgaacatt
     3781 acttgcaatt cctgctttag ccaattcttg gatgatgagg ttgcgttctt ctaggcttgc
     3841 tccttctaca cgggtgatgt agaggtggcg tgaagattcg acagtttcag tcttgtgtgc
     3901 caaaggatgg atgcgagaac ctgcaaaacc actatcatag cggtccacaa tgtccttacg
     3961 gcgttgcaac aaacttggat agcggtccaa ttgtaccaaa ccaagtgaag ccatgatatc
     4021 ggtcatgttg cacttatagg ctggtgtaac gatatcgtat tcccatgacc ccagttgcat
     4081 cttggcaaga gcatccttag tttgcccgtg aagggaaagg atttggaatt ccttgtacat
     4141 ctcttcgtca tcaatcactg gattggctct ccaagtcgca cttccacctt ctgccgttgt
     4201 aaagttctta acggcatgga atgagaagga agtaaagtca gcgatagaac cagaaggttg
     4261 tcctttataa gtagatccca aagcgtgggc actatcagag acaatgacaa tacggttaaa
     4321 ggccttttgc cacttgcttg aagcagtaaa gaagtcacgt tttttctcca cgacttggaa
     4381 caaacggtca taatcgcaaa caatccctgc gagctctact gggataatca ccttagtttt
     4441 ctcagtgata gcttgctcaa gcaggtcata gtccatctca aacgtatctg cttggatatc
     4501 caccatgaca ggggttgctc ccacgtgcgt aatgacacta catgaagccg tataggtcat
     4561 ggctggaacg atgacttcat caccaggtcc cacttccaaa acgcgtaaaa tcaactccag
     4621 agcggctgtc gcagagttga gacaaacagt cttaggtgtc tgtgtgtaaa gagacaagcg
     4681 gcgctccagt tcttttgttt taggacctgt tgtgatccaa ccagaacgca gggtatccgc
     4741 tacttcagca atttctgctt ctgtgatatc aggcggtgaa aatggaatat tgtaatttgg
     4801 cattgatttg ctccttttat ctgtactcat tttcttatga ctactttatt ttagtacctc
     4861 aaacacggtt tgaaacatga ttttgatgtc cccaaagaaa ctaaactctc ggagataggc
     4921 gaggttatag tgcatctttt caggaagaac atgctccaca taggcctgat caactgacag
     4981 acctttctcc gtcatttgac tgatgatggt gtcctcatcc ttgtagttga tgctggctgg
     5041 agaggtaatc cctgcttgca agagcaaggt tgccatcatt tcagggctat actgctctgt
     5101 ataacgtggc acttcaggtc gtgtaccgac aaaggacatc tcacctttaa ggacattgac
     5161 caactgaggc agttcgtcca aacggacacg tcggatgaaa tttccaacct tggtaatgcg
     5221 gctatcgtta gcagaagtca ccagacttcc ttttttatcc gcatccgtca ccatggtacg
     5281 aaacttccaa atcttgaacc gacggttgta ctgggtcaca cgctcttgct tgtaaatcac
     5341 tggccctttg ctatccaact tgatccaaat gctcaagatg agaaagatgg gagaggtcag
     5401 aaccagtaag accaaggcca aaacccagtc caagcaacgc ttgaaaatca gcgaaccctt
     5461 ccttttagag acaagctggt agtaagactc aacctcgctt gatttcattt ccacaggcaa
     5521 gtcttcccat ttcagcatgc tgttctcctt tgtttttatt atactatttg tcaacatttt
     5581 tcattatacc acaaaatgga aaaggcggtg aaagaaatct gtaatttgaa ggatttcctt
     5641 ctagtactca atgaaaatca aagtacagct ttgagattgc agataaagct gacatggttt
     5701 aaagagattt tcaaagagta tcggccatgg cccctgcctg caaactatac atcttgtgat
     5761 aggttcctcc cagagccaag agttcctcat gggttccact ctcgataatg cgtcccttat
     5821 ccaagacata gatgcagttg gcatcttgaa tagtagaaag gcggtgagcg atagcaatag
     5881 ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac caagctttct gtttcagagt
     5941 caatattggc tgtcgcttca tccaaaatca ggattttagg ctggctggcg actgttctag
     6001 caaaggcaag aagctggcgt tgcccagtag agaagctcaa accacgctcg gaaacagggg
     6061 agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc atccacaaag gctgccgcag
     6121 cctgaacctg ctcatcactg gtttcttggt acatggcgat attggactta atagttccat
     6181 gatagaggaa gggttcctgc aagaccaaac cgatgttttt tctcagctct tcttgactga
     6241 aatccctgat atccacatca tccaagagaa ctctccctga ctggaattca taaaagcgca
     6301 tgaggacatt gataatagac gatttccctg aacctgtatg acctacaaag gcaatggttt
     6361 cacccttatt aacagagaaa gaaatgtcat ccagaatcgg atgtttaccg tcatatgaga
     6421 aacacacatg ttcaaaacgg atattgcctt cttggacttt ggcttgccca ttttcttgaa
     6481 gaggttcata ggtcctctcg tctatcaggg caaagacacg acctgcagaa accatagccg
     6541 tttgcagagt tgaaaagttt tgcgtcacct caatcaaggg gtcaaaaagg cggttgatgt
     6601 actggataaa ggcatacatg gtcccgaccg ttatcccgat agaaaaacca cggtagccaa
     6661 agtaggccat caagactgca tagcctagaa gtttcagcaa actcatggca ggtctcaaaa
     6721 agagggcatc caaggctaca gaacggttgg cgtagaccaa gtgttcttgg ttgatttcat
     6781 caaattctgc ctgcaggcgc ttctcttgat taaaagcctg aataatcctg attccctcga
     6841 tattctctgc cagcttacta ttgatatctg acaagagact tctggttttc tcgatgattt
     6901 tcactgactt ttttcgatag agattgacca aaaggaaaat caaagggaga aagagcaaga
     6961 ctaaagccgt caaacgaaaa tccagcacca acatggtata aagggttgtc agaaagataa
     7021 aaactgctga gataaagctg gataaaatcc cagaaaacat atcactaatc gtctcggtat
     7081 cgttggtcaa acgagaaacg atagaacctg ctggcgtctt gtcaaagtaa gacatgccca
     7141 gtttctccat attggcaaag gcatcccgac gaatatccct aacaatactg taagacacgc
     7201 gcgcaaagag aagattgcct acatactgaa ctacagtttg taggatgtag agaccatagt
     7261 agaccagcaa aacggtaacg gctagttggt taagattgct gagatactgg tcgataaagt
     7321 gggaagccac gaggggtatg acacttttaa tgaccgtcgt cgctaggaga aaactgagtg
     7381 ccaaaaaggt caggagtcta taaggcttga gataagacat caagcgcttc aatacagccc
     7441 attgttcttg tttattctgc atcttcttct cctttcattt ctaactgctg agactggtag
     7501 gtttgggcat accagccatc catcgctagc aagtcttcgt gcctgcctcg ttcgataatt
     7561 tgaccatttt gtagaactaa aataaaatct gcatggacaa cagcactgag gcgatgggca
     7621 gtgataatgg ttgtcttgtc ctttcgcgtc tccttgaggt tgtcgataat cgcatactct
     7681 gtcttggcat ctacggcgga taaggaatca tccaaaatca agatatcagg gtctaaaatc
     7741 atagcccgac tcatagccaa ccgttgcttt tgaccaccag aaagactgac tcctttttca
     7801 ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat cttggtaaac tcgggctagc
     7861 ttagtagctt cctcgaccgc tgaaaggggc aagttaggat tgccaaagcg gatattgtct
     7921 aggattgaag ttgcaaagag aaactggtcc tgaggaacat agcccatgag actgcgaagg
     7981 tctgtcagac gatagtcccg aatatcgtga ccgtttagat aaatggcacc cttatccaca
     8041 tcgtattcac gcaagaggag cttgattaag gacgttttcc cagagcctgt ctgcccaacc
     8101 aagcccagtg tttgcccttt tgccaaacta aagtgaatat ccgtcagtgt ttcctcattt
     8161 tcaaaagcaa agctgtcaat ggcatactcc aaacacccat tttcaatacc atccagagga
     8221 aactcagggt cttgtacagg agattcctga gacaaaagat tttcaatccg ctggtaagaa
     8281 accttccctc gctgagtagt attaaagagg aagccgatgg ccataagagg ccagaccagc
     8341 atatccaaat agctgataaa ggtgactaga ttcccaactg taatctgccc ttcctgaacc
     8401 atcaaggagc caaccaaaag cgttaaaaca taggacgaac caacaaacac gagaaccata
     8461 gggtcaaaga gactatcata tttcatggtt tgcaggttct tttggaaggt taattcattg
     8521 actgcctgaa aagacttcaa ctcgtctgcc tgataaccga aagacttggt cactttgata
     8581 cctgatacgg actcctgtac cttgttattg agttcagaaa aagcagcttg ggattcgcca
     8641 aaggccttat gagtctttct ccctaggcga ctagtcgcat aggccatgaa aggtaggggg
     8701 agaatggcaa caagagtcat ctgccatgag atgctaaaga gcatggtcaa caaagtcacc
     8761 agagccgtga tagaggcatc caccgcagac atgacaccgc cacctgctaa acgagtcaag
     8821 gcattgatat cattggttgc gtgtgccatc agatcacccg tccgataggt ttgataaaag
     8881 gctgatgaca tttttgtgaa atgcttaaac aagcgagacc gcatgatctg tcccaagcaa
     8941 taagaggtcc caaggatata catacgccac acatagcgca aatagtacat accaaaggct
     9001 gcaagtagca agtaaaatag gctaagaagg aggtcctgct gggttaattg ccccgatgtg
     9061 atggcatcaa tgacccgccc cataaccata ggaggaatga gattgagaac ggaaaccaag
     9121 accagggcca caatcccgac tagataacgg cgtttttcta acttgaaaaa ccaccaaagt
     9181 ttttgaataa tggacataaa atccctttct gattgcaaat ggaaacctga agccaatact
     9241 caatgaaaat caaagagcaa actaggaaac tagccgcagg ctgctcaaag cactgctttg
     9301 aggttgtaga tagaactgac gaagtcagta acctacatac ggcaaggcga cgttgacgcg
     9361 gtttgaagag attttcgaag agtacaagac cccaggtttt tcttattcat aagttacgac
     9421 tgtaacagca cccttgtcat attcagcaat aaagatattg gctacattgt catgcccttg
     9481 tttactgagg ttatcaagca accactcttc gctacgacca atcgattcca agacatctac
     9541 ttgaatcaca ccgtcagtca caactggata cttagaattt tcatctccca tttgcacaac
     9601 gatgagttgc ccattttgct cttgcacagc tcgtttgact tgcttcatct ggaaaatccc
     9661 ttggccacga agtttgaggg ctacatccga tgcagacaaa ccaactgaac gacaggctta
     9721 tgggtcaata ttcccatttt tgataaggag agttggctta ccatcaatca aacgtttcac
     9781 aaagtgaaca ttgttgttga gctatttgag agtcaagacc agtttgatta aaatttcgat
     9841 ataattaagt gtcatttgtt cacatccacc agttcaattg cgtctgtctt atacaattcg
     9901 actttctcta acaggtactt gtctggctca cttccgttta gggcacgata atagcgatct
     9961 cccaccttga taagtgcgcc atctgtgttt gtggaagtat taacatagac ttctgacttg
    10021 tctactccca aatctttgga aacaacctcg atgaaatgaa gtgaagtttg aaatttattg
    10081 ttagaaactt gattgttttg ataagtcgtg atgctgacca aaagcagagc taaataaggc
    10141 cagagctgaa atcatgacca actcacgaaa ttcggttccc tttttatcat ggtatgcctt
    10201 gaaagcaaaa aaactgtcat agctaataga acaatcccaa agccaaccat gataccattt
    10261 tgctgaccga tttggctgag tacatagtca taagagtaga atttcatgta ttttcactcc
    10321 ctttcataaa atcattctta attataaacg aaagagagta atttttcaaa ccatacgttg
    10381 gggaaataga tctttttttg gtataataaa atctataatc tgaatgaaaa ggtaacttta
    10441 tgaaacttat ctcatggaat attgattccc taaacgctgc cctaactagt gactcagctc
    10501 gtgccaaatt gtcccaagaa gtcctacaaa ccttggtcgc tgaaaatgct gatatcattg
    10561 ctatccaaga aaccaagctt tctgccaaag gacctacaaa gaaacacgtg gaaattttag
    10621 aagaactctt cccaggctac gaaaacacgt ggcgctcttc ccaagagcct gcccgtaaag
    10681 gctatgctgg aaccatgttc ctttataaga aagaacttac acccactgtc actttcccag
    10741 aaatcggtgc cccttctacc atggacttgg aaggccgcat catcactcta gaatttgatg
    10801 catttttcgt gacccaagtt tacacaccaa atgctggcga tggtcttaaa cgcttggaag
    10861 aacgccaagt ctgggatgtt aaatatgctg agtatttggc tgaactagac aaagaaaaac
    10921 cagtccttgc gaccggtgac tacaacgtag cccacaatga aatcgacctt gcaaatcctg
    10981 ctagcaaccg ccgttcacct ggatttactg acgaggaacg tgctggattt accaacctat
    11041 tggcaactgg atttactgat accttccgcc atgttcatgg cgatgttcct gaacgctaca
    11101 cttggtgggc acaacgcagc aaaacttcta aaatcaacaa tacaggctgg agaatcgact
    11161 actggctcac aagtaaccgt atcgctgaca aggtcactaa atctgatatg attgactcag
    11221 gtgctcgcca agaccataca ccgattgtct tggaaattga cttgtaagga ttttctatat
    11281 ggactacaat gcggtcattc ccgagttgct tgtatcgaat atcgaacagt cccggtcctt
    11341 ctactgtgat ttactgggtt ttaggattga ataccaacgt ccagaagaaa actttctctt
    11401 tctcttgaag agtgtcaact aatgttagag gagggaacaa aggatcaact agctgaactg
    11461 acctatctat ttggtcgtgg agtcaatctc tcctttggca taaaggatgt ttcaaaactc
    11521 tatcaaagag tgatgaaggc aaactatcct atttatcgtc ccttgaccaa aagaaagttt
    11581 cgtgtcagtg atcactatat ctatcctcat gaatttgcag ttttggatcc agatagctat
    11641 tttttaagat ttagcgagta gaataataaa aattgggaaa agtctttaaa gttagaaaaa
    11701 ggcatattgt caggtgtcta aaaacttgat agtatgcctt ttatgatgga aaaatcttct
    11761 aatactcttc gaaaatctct tcaagccacg tcaacgtcgc cttaccgtag gtatatgata
    11821 ctgactctgt caattctatc cacaacctca aaacaatgtt ttgaggttgt ggatagcttc
    11881 ctagtttgct ctttgatttt catttagtat aaatgttagc ttacaatgga gtttttgttc
    11941 acccctctct tctgtttgtt cgttttttaa accaaaatac taacaaaata gttgatttct
    12001 aaagttattt agtgtaaaat aaaaacattt gctcaagcct atttaaaatt gaatatcgtt
    12061 ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa ggtgccggaa cacctaacaa
    12121 taagtaagtc agcagtgaga tatggccgtt tttgccatgt ctatttgggg gacttactta
    12181 gagattaagt aggtcttttt tgaatatttt taatatttcc cttaattagt gcggacggga
    12241 ggtgaaatta tcctgtgaat aatttcagga atccagggaa tttcatccct aatttttgag
    12301 cccctagctc tttcatttct aggcttaggc taaaatagtt ccccgaacta ttttactctc
    12361 aaaaatcccg tcatagacaa taacaagatt attgtctatg ataccactac aacgggaaat
    12421 atttgataag actcgcttcg ctcgtaatag ttttatcaaa tatatagtat tagcaaaagg
    12481 gatcactata gaaacattta aacaacaagt aaattaactt ttagacttta ggaggtctta
    12541 tgaaattatt agaagaacgc atcctcaagg atgggcatat cttgggtgat aacatcctca
    12601 aggtagattc ctttttaacc caccaagttg actttagctt gatgcgagag attggtaagg
    12661 tttttgcgga aaaatttgct gctactggca ttaccaaggt cgtaaccatt gaagcatcgg
    12721 gtattgcccc agccgttttt acagctgaag ccttaaacgt tcccatgatt ttcgccaaaa
    12781 aagctaagaa catcaccatg aacgaaggca tcttaactgc tcaagtctac tcctttacca
    12841 aacaggtgac cagcaccgtt tctatcgctg gaaaattcct ctcaccagag gacaaggttt
    12901 tgattatcga cgatttcctt gctaatggcc aagctgctaa aggcttgatt caaatcatcg
    12961 aacaggccgg tgccacagtc caagctatcg gtatcgtgat tgagaaatcc ttccaagatg
    13021 gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc acttgctcgt ttggatcgtt
    13081 ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta atgcaaactc aagaaaaaca
    13141 ctcgcaagca gccgttcttg gcttgcagca cttactagcc atgtactcag gatctatcct
    13201 ggttcccatc atgattgcga cagcccttgg ctattcagct gagcagttga cctacctgat
    13261 ttctacagat atcttcatgt gtggggtggc aaccttcctc caactccaac tcaacaaata
    13321 ctttgggatt ggactcccag tcgttcttgg agttgcattc cagtcggtcg ctcccttgat
    13381 tatgattggg caaagccatg gtagtggcgc tatgtttggt gcccttatcg catctgggat
    13441 ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc aatctcttcc catctatcgt
    13501 aacaggatct gttattacca cgattggttt aaccttgatc cctgtcgcta ttggaaatat
    13561 gggaaataac gttccagagc caactggtca aagtctcttg cttgcagcta ttactgttct
    13621 gattatcctc ttgatcaaca tctttaccaa aggatttatc aagtctatct ctattttgat
    13681 tggtctggtt gttggaactg ccattgctgc tactatgggc ttggtggact tctctcctgt
    13741 tgcggtagct ccacttgtcc atgtcccaac tccactctac tttgggatgc caacctttga
    13801 aatctcatct attgccatga tgtgtatcat cgcaacggtg tctatggttg agtcaactgg
    13861 tgtttatcta gccttgtctg atatcacaaa agatccaatc gacagcacgc gccttcgcaa
    13921 cggttaccgc gcagaaggtt tggcggtact tctcggagga atctttaaca ccttccctta
    13981 caccggattt tcacaaaacg ttggtttggt taaattgtca ggcatcaaaa aacgcctgcc
    14041 aatctactac gcagctggtt tcctggttct ccttggactg cttcctaagt ttggtgccct
    14101 tgcccaaatc attccaagct ccgtcctcgg cggtgccatg ctggtgatgt ttggttttgt
    14161 atctattcaa gggatgcaaa tcctcgcccg agttgacttt gctaacaatg aacacaactt
    14221 ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc aacaacagta atctctttgt
    14281 cagcatgccg acagccttcc aaatgttctt ctcaaacgga atcgtcgtag ccagcctact
    14341 cgctattgtc ctcaatgccg tattaaatca taaaaagaaa taagaaaaag aggtgcgagc
    14401 ctcttttttg tttatcacaa attgattata aatacaatca atcccaattc ccatctaatt
    14461 gaattggacc tatttcaaat tctttaaaat attatgttcc aaatcgttaa tattatataa
    14521 gaatggtaaa atatcaaatg tttctcgtaa attattctta gccttatacc aaccttgtcc
    14581 atcagtaatc cacataaact caacattagg aatagcttta gtttcttcag caatcatttt
    14641 gtaagatcta gccgtctcat ttaattttga accacttcct gaataaaaat taacctcaat
    14701 cagataaagc acttgttcat tttttatgac aaaatcaaaa cgtttcacag tattcccatc
    14761 attcgtaata gcagataaat cgacagaaaa aatttcctct atttcatttt gttcaatctc
    14821 tttaaataaa ttctctccta aaatataccc ttcagcttca agatagcttt gaacaatatt
    14881 ttccatcgca tctccagtcc gatttttgcg cccattagta tccataccaa cctcaacacc
    14941 tgtaacgtag tcaactaaat ttgatactaa atgattttgc aataaatcaa atatacctga
    15001 tttttccaaa aacatagtat attcttcaat actatagttt cgtttactaa aatcaaaata
    15061 gaaatctttt atcggatcct taacaataat cgtatctctc aaacgtttag caataagtag
    15121 aggcacaact ttcaaaattt ctggataatt ttgatataag tctaaaaaat cctcttgtat
    15181 atttttacta ccaataagac tattcataat atttagagca acttttatac tagatacatt
    15241 tttataaacc ttaggaaaat ctgtataata agtccagtca gctactgtgt cggtcatcgt
    15301 tgacaaccac tcatcaaaat ttctagtttg tttcattttc tgcctccaac ctcttccttg
    15361 caatttttaa atattctttt tcagcatcga tacctataaa tcttctacct aaccgcttcg
    15421 caacaacacc cgtagtgcca ctaccaacaa atgggtctag aatatagtca ccctctttag
    15481 tagaggctaa aataatacgt tctaacaaat actctggttt ttgagttgga tgtttcccag
    15541 cccatttttc aactttcttt gttaaagaac cggtccagac atctttcatt tgttttccat
    15601 cattcaattc tttcattaaa tcataattgt agtaatgacg agctttttta tcattttttc
    15661 tggcccataa aatggtttca gtagaatggg taaaataacg acaagataaa ttgggggcag
    15721 ggtttgtttt ctgccaagta atattattca gaattttaaa accttcttgt tctaatgcca
    15781 ttccaactga gtatatgttg tgcaaactac ctgaaatcca taccgtccca ttaggcttca
    15841 gaacttcttt tgctaggcga atccatttac gattaaactc atgtttttct tcgaatgaag
    15901 aaattttatc ccaatctcct ttatcaacag aaactacttg tcccccagaa ttagatattc
    15961 caccattact taaaaaataa ggtggatcag caaaaatcat atccatactt tctggtttca
    16021 tttttgataa gaacttgaac gtatctgaat gaacaagaat catcttattt ttattgtagt
    16081 atggttttgt cataagaaca cctccatact tatattcgtt atttttcata atttgtgact
    16141 ataatttcag aaatttttcc tcgacttgaa gattttgctc cattagttcg ggtagcttca
    16201 acataatgta tattaaaatc cttatacaac tcctctacta aagcactaga agaatttgat
    16261 aacataacat aagctcctgt atcactcaat ctcttaaagg catctcttaa tcttacttga
    16321 tctgcaaaag agaatccctc atgagtataa gacgtaaatg cactcgtctc agacaatgga
    16381 atatatggag ggtcaaaata cacaaaatct cctgttcgaa catctacaat tgccttttca
    16441 aaatctccca ctttaatttc tagttgattg ttatttatat aaactgaaat agcagatatc
    16501 aattcctcat caacaatttt aggattctta taacgtccat atggaacatt aaattgattc
    16561 ttagaattca cacgatatag accattaaag ttcactctca acatatatag aatacgtgca
    16621 gctctttgta cttcggacat catatctatt ctttcatcac gatctgcaga acgtaaatct
    16681 aaataatatt cttttgaatt atattcctga tgaactttca aaatttcaat caattcttga
    16741 ggattgtcct taatttgttg atagcaattt attagttcag cgttaaaatc attaataact
    16801 gcatctttag gagccaaatc aaaaaataaa gctccacctc caacaaaagg ttcgaaatac
    16861 ctgttatagg ttttaggtat taattctcta ataacaggca ataattgtct tttaccacct
    16921 gtccatttcg tgaacggttg taaagtaact ttctttattt cttttatctt catgctttta
    16981 attataccat agaaattaaa acacaactct tgtattttct accacattac taaattttct
    17041 attttagaat taaatcatat caatatcaaa aaatgagtaa ggcaaatctt ataaattcca
    17101 aaattcacct cactctatta aattactctt tatatcctta cctgtctgtc ttctgaccgc
    17161 cggcctgtga caaacatggt aaaggttgct ttgcagacat ttctgccttc ttgattggtg
    17221 atatccacat ccattacaca ggttgtacga ccttgatgga cacattctcc tttaatggtc
    17281 aatacatcgt cgagttttcc tgccttaagg tagttgatag aggattggag tgtcacccca
    17341 tcaagtccca gcgagataac caccaaacca ctgatttggt cacatagcgt gaatagatag
    17401 ccaccatggg cattgccata gtagttgagc gacgagttca ctactttggt cgtcaccaca
    17461 acgtgaccat ctctcatttt ttcaatttcg taattttcaa aggcagatat agcgtcaaaa
    17521 tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac actatgatac tactttttat
    17581 aggactgtgc aaggagaaag ctcctagtct agtgaaattc cgacctgttc cacaaagcgc
    17641 ataaaggccg cctgtccctg ctctgtctgc ttgtagactc ctgcatcctc aagtacacgc
    17701 acaaagatag cccccacaga gtccttgacg attgcaaggg ctttttcttt atccgttagg
    17761 tctggatgtt gggatttgag ttggtctgcc cactcctgat gataatcggc aactgtaaca
    17821 gcttctccta caagatagct agcgacttgc tccacttctt ctttcagacg tggtggcaag
    17881 attgccaagc ccatgacctc aatcaagccg atattttcct tcttgatatg ttggacatcc
    17941 ttgtggggat gatagatgcc atcaggatgc tctgctgaag tctgattgtc tcgcaagacc
    18001 aagtccaact caaactgtcc atcacgctta cgcgctattg gtgtgatggt gtgatgcggt
    18061 gtcccgtctg tctctgctaa aatctgcaca ctagaatctg aatactgacg ccattcctgg
    18121 aaaatcttat cagctaagtt aatcaaatcc tctttggaat ccgaagtcaa gcgtaggaca
    18181 gacattggcc acttgataat tccagccttg acctgctcaa aaccagcaaa tcggaaggtc
    18241 ttttgcaagg gagccaattc cataggaaat acgtgacggc ctccctgata atgatcatga
    18301 gttagaatag agccccccac aatcggcagg tcggcattag atccagcaaa atatcctgga
    18361 aactgctcta cgatagccaa cagacgttca aaactctgac gactaatggc catgggacga
    18421 tgctggccat ctaaaaagat acaatgctca ttaaagtaag catagggcga atactggaaa
    18481 ccccattcct gaccaaccat ttcaaaacgg ataatccggt ggttggtgcg agctgggtgg
    18541 ttgacccgac catggtaacc ctcattctct aaacaaagtt gacactgagg ataattacta
    18601 gcttgcacca acttggctgc cgcaatctct ttcggatcct tttcaggctt agagagattg
    18661 atggtaattt caagttctcc ataatcagat ggaacacgat aagcgatatt tttagcaatg
    18721 gccttgagtt tgatgtagtc atttttctga ctgagttgat aaaaatcctc tatcgcttgc
    18781 tcaggagagt aggcataggc ttcccagaag tcacgattga cctgactcgg acaaggagtc
    18841 accaagtcca tcaattcagt accaaggatt tcacgcgcag tctgactatc ctcaatcgtc
    18901 tctaatcgaa cggcttcctc aactagctgg tccttgaggt caatcaattt atccagattg
    18961 gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa cacgattggt caggtagatt
    19021 cgatccattt cctcaaatga actttcagaa atgacatgtg ttacaaattt atctactaag
    19081 atcactatag agcctccttt tgactagtca aggacgcgag tgccacctgc aacttcagcg
    19141 atatagaagc ttggagcgta tccaactact tcctcgtagt gtttgcctac agcttcctta
    19201 aaggcctcaa cagtatcttt ttgaaccaag gcaatggcac agccaccaaa accagcccct
    19261 gtcatacgag caccgagaac tccttcttgt gcccaagctg tgtgaacaag agtatccaat
    19321 tccaaaccag ttacttcata atcatgctcc agagaaacgt gtgacgcatt catcaaacga
    19381 ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag ctttaagggt acgttggttt
    19441 tcaagcacag catggcgagc acgtttcaaa cgattttcat ctttaatcaa atagctatat
    19501 tggtcaacgg cccactcgtc caattcaccc agggtctgaa tatccaaggc aacttgcaat
    19561 tcttccactg ctttttcaca ctcagcacga cgttcattgt atttagagtc cgccaattca
    19621 cggcgtttgt tggtgttcat gataacaacg acattgtcct tcaaatcaag tggcaccaaa
    19681 tcatactcta aggtgttggt atcaaggtaa atagcacgtt gatcggcccc cataccaata
    19741 gcaaactggt ccatgatacc agagttgact ccgataaagt tgttttctgt ttgttttccg
    19801 attttaacca aatcgagacg ctctaatttt aaatcaaaga gatgctctgc cacgactcct
    19861 gtcaagagct ccaaggatgc tgaagaagac aagccagcac catttgggat attcccataa
    19921 acataaaaat caaaaccttt gtcaatcacg tgcccagctt cttgcaagaa atgaaggaca
    19981 ccttttggat aattggtcca gttgtgctct ttttcaaact tgaggtcagc gagaggcact
    20041 tcgataatgc ccttgtcctc aaagttagct gagtagaaac gcaagacttg gtcgtcacgc
    20101 ttacgagctg caccgtaagt tcccaaggaa atagcagcag gaaaaacgtg cccaccgttg
    20161 tagtctgtgt gttcaccaat caaattaata cggcctggtg aaaagaaggt ttggtctgct
    20221 tcttgaccaa aaacagcaag aaagtctttg cgaaggactt cagtagtaag atgttgtgcc
    20281 atatgaattc tcctttgact gtccgttaag ccatcttaac gtgtaatcgt tttctttcta
    20341 ttgtatccaa gaaatttccc aaggtcaatc ctttttacta aaattttact aaaatatcag
    20401 taaaaagaag aaaaatatga tatactaacc taatcaagga ggatttatgg ctaccttaaa
    20461 agacattgca cagctagcct ctgtctcaat cgcgaccgta tcccgtgtcc tcaaccgcga
    20521 ccagagccta tctgttacag aagaaaccag acaccgtatt ttaaccgttg ctgaagagtt
    20581 aggctacacc aaacacctca agacaggcga gtcccacaag cccaagcaaa agattgccat
    20641 tatccaatgg gtcagcgaac aaggggagct agacgacctc tactactacc agattcgcct
    20701 aggaatagaa aaaagagccc aagagttgga ctacgatatc ttgcgctatt ttaatgacca
    20761 tccttttacc ttaagcgagg aagtgattgg gattctctgc atcggaaaat ttagccgagc
    20821 tcagatttct gcctttgaag aataccaaaa gcctcttgta tttctagaca gcgatacact
    20881 ttccctggga catacctgta ttatcacgga tttttacact gctatgaaac aggttgtcga
    20941 ttatttcctc agtcaaggga tggaccgcat cgggattcta acagggcttg aggaaacaac
    21001 agaccaagaa gaaatcattc aggacaagcg tctagaaaac ttcaaaaact acagtcaagc
    21061 gaggggaatc tatcatgatg aactggtctt tcaaggaaga tttactgccc agtctggcta
    21121 tgacttaatg aaggaggcca ttcagagctt gggagaccaa cttccgccag catttttcgc
    21181 agccagcgat agtttagcta tcggtgccct ccgtgccctc caagaagctg gaatcagcct
    21241 gccagatcgc gtcagcctca tttcattcaa cgacaccagt ctgaccaagc aggtttatcc
    21301 tcccctctcc agcatcacag tctatactga agaaatgggg cgagcaggta tggatattct
    21361 taacaaggaa gtcctccacg gtcggaaaat ccctagcctg accatgctgg gaaccagact
    21421 gacattaaga gaaagtaccc taaatcaaga ataggataac ataaaaaacg aatagagttc
    21481 taaaactcct attcgttttt tattcgatta caatcataga cttaatggtc ttacgttcat
    21541 ccatatcttt ataggcctgg tcgatatctt ccagtttata acttgaagta aagacgcgac
    21601 ctggattgat atcaccatca aggacggctt ttagtaaaaa ttgcttatcg tatgttgtag
    21661 cagaagctgc cccacctgct acagagatat tttgcataaa tgtcgaacca agagcacgat
    21721 tattatagtg tgggactcct acaaagccca tacgccctcc attatgaaga acacctagcg
    21781 cctgttctat agcagcctcc gtaccaacac attcaagtgc tgcgtctgct cctccaccga
    21841 ggatttcacg caccttggta attccttctt gaccacgttc tgcaacaaca gctgtcgcac
    21901 ctgactccat agccatcttt tgacggtctt catgacggct cataaggata atttgtgatg
    21961 ctccacgcat cttagccgcg atgacagcac attgaccaac agccccatca ccgataacaa
    22021 caaccttgtc ccctttttga acatttgcaa cacgcgccgc atgatagcct gtcggcatga
    22081 catctgcaag agtcaaaagg gactggagca tcccttctgt atagtcagaa ggttgaccag
    22141 ggattttaac cagcgcccag tttgcatagt ggaagcgaat atattctgcc tgaaaatcac
    22201 cccccaaatt attgccaata tgattgtcgc aagaaccgtc aaatccagca agacaggcat
    22261 cacactcacc acatccatgt gtaaaaggga caatcacaaa atcacctggt ttcaccgtcg
    22321 taacggcttc cccagcttct tcaacaatcc caatcgcttc gtgtccacta tttttgtgtc
    22381 cagctttcgt ttctggatta cggtacctcc ataaatctga accacaaacg cacgcacgaa
    22441 ccacacgaat aatcacatca tccgcttcta ttatttgcgg acgttcaatg ctagcaagtc
    22501 caacctgacc tgcctttgta tatactgctg atttcattta aaattttcct tccttataaa
    22561 gtttaatttt gagatttaaa cgatttaaag ctgtctgtag ctgagacaag cgctcctcta
    22621 atttttgctt ttcctcttct aaaataccaa gcctctcctc tctcgtttca tctccctttt
    22681 ggtagagcga catatagtca actaaactat ctacagagac acccgccgaa cgaaaacact
    22741 taataaattc cagcgcttcg atatcctgat cttgaaaatc acgaatccca gtagcagtac
    22801 gagtaatcgg tggcacaaga ccaacccgtt cataataccg aatcgtatcc gctgaaattc
    22861 ccaacaaatc actggcagat ttaatattca cacgctaacc tcctctcatt tcattcactg
    22921 aattcacgct attctaactc acttatctta ttatataact ttgagttgac tccaagtcaa
    22981 gcattttgta tctaatcgaa aaatttttat cattaacaat catatatatg gagtttatac
    23041 aatgctcttc tcttaccaat ttttgaaata tttaaataat aaagaaatta ctctattcca
    23101 aataagatag tacccaagta tttttcactt ttttctaatg ttggtgctca taactccgtt
    23161 ccaagtcaca cacctttcgc ttatgggttt ggtgagtttc taggtcagca tcaatttcaa
    23221 tggtaatatt ttgaaaacca caatctttta ggaaaattcg aatagactct ttacaagttt
    23281 ccatatgttc catttctttt agacaaacat ggacaatggc atttttttcc aaagcatcca
    23341 tagtccagag attaagctga ttaaggctga ccacattgtc caatcgctcc aggccactct
    23401 ttacttgctt gatatcaaga ccttctggca cagcatccaa gaaaatcttg agtgtagacc
    23461 aaaaacgtgg aagggctttt gaaagaataa agaaagaaat gacaagggac aaaagaggat
    23521 ctaggatata ccagtccgta aatcgaagaa caatcgccat caggataaca gctacccacc
    23581 ctagcgtatc ttccagaaaa tgcagactca gaatagactc attctttgtc tttcccttac
    23641 caaccaccag actcgctaac agattgatag taatcgcaat aattcctaac cagagaatcc
    23701 cctcatcatt gactggttgc ggatgcaaaa tcttcgtgac attttccaaa atgactagaa
    23761 cagagcctgt tacgagaatc acagctgtta ccaaggctcc tagcaggcta aaccgcttat
    23821 agcccaaggt gtactgattg tcttcttcac gattggagat tgtttctaga aaagctgata
    23881 ttccaattgc aatcacatct cccaagtcat gcacagagtc agcaagaaca gcgctagaac
    23941 caaatactcc acctgcaata aactcaacaa tggcataagt caaatttaag aaaaaagcca
    24001 cccaaacagc atattttgcc ttcatatttc tcattccttt gttataatag gtttatgaac
    24061 accttgttca ttatcattat ccactaaaac tcaaagaaag gatagaagca aaacgtcagc
    24121 tttattcagt tctgaacaat ttgccttaag tgtccatatg actaacattg accgccgtat
    24181 cagcaaaacc aaaaaagcca tctatcaagc ttttatacaa cttttgaatg ctaagggcta
    24241 cgaggccact actgttcagg atatcattaa tctcgcagat gtgggaagat ccacctttta
    24301 ctgtcactat gagagtaagg agcttcttct ggaccagctc tgccgctacc tcttccatca
    24361 tctttttgaa agagagcaag ccatttcaac cgaggactac ctcgcccacc tctttctcca
    24421 ttttcataaa aaccaagacc atatcaccag tctgctattt tccaaaaatg actacttcct
    24481 ccgtcaactc cataaagagc tagaacacca tgtctattcc gtgctagctg ataatttaaa
    24541 agaagcccac cctaatatgc ctacttctta cctccaacac ttggtcgtgt ccaactttat
    24601 cgagacattg acctggtggc tcaaaaaagg tcaagatttc acagaccagg aagttgtcca
    24661 attttatcta gaccttctca ttcctaaaaa ttgaatatag agtaaagctt cagttgtctt
    24721 atttctaggt tactgagttt tttatctttt caacaacaaa agaggacccg ccgatcctct
    24781 ttttcatact ataaatcctt gattatcaac tatatctgtt ttaatcaaaa tctcaaaaca
    24841 gcactttcaa acatcttttc ctagttaagt aaatcagtat tctgcttagc tgccttgctc
    24901 cattgatacc aaccaactag actgttaatg agataaatta gatatttccc ttgaatttgc
    24961 aggctttctc cccaccagag atagattgaa aaaacattgg tagccgccca gaatatccac
    25021 tgttcacggt aaacagctgt catgaggatt tgccctaccc cattggttgc atctgtgatt
    25081 gaatcacgat agggacgatt ggcaccaata gactgataaa tgaagccaaa ggccaaccac
    25141 caaagcacac taatggaaag atactttgtc cagcccttgc cgtccagttt acgcgcgaca
    25201 aactcctgct tttccttctt aaactgtgcc tgataaatcc aaactagaag tccaattggc
    25261 tgcatgactg tgaagtaaag tgtcgtcagc acctcaccat aaaagccttt ctgtagggcc
    25321 aaaataaggt aaataacaga gttaatcaag ccaaaaagat aattacttgc tcgaccttcc
    25381 gatacaaaga ttacacagat aatccctgtc aagctacaaa tcatcccaat ccagtcaaca
    25441 atacgatgtt cgtaaaccaa ctccagccag agaggaaaac ttcctaaaac cagcaaataa
    25501 atccactggg caaaactacg atgggcaaag aggtcatccc agatagcctt catagttcct
    25561 gaaaatccta aatcagccat agccgcaacc atacgacggt aaccacctga catttcacct
    25621 agggttgttt tgatattttc aattttcttt tgcaaataag tatgcatcat ttctcctttt
    25681 gtttttaaag agccgtgtct ggatagactt tcggacgcaa cgctctatta gataatgaac
    25741 tgcctataca caagatttct aaccttagtc gacatgagct gaaacctctt atttgttaag
    25801 tagttcacaa aatattatac acctatttta tgaatagtca actgtcttta cagtaaaatt
    25861 ttagaaaatc atgaaaattt tctctttctt tccattttaa gtgacattca gtcattctca
    25921 catcaaaaaa gcccagacga aattgtctga gcattctttt atctagtcgt ttaaggaagt
    25981 tgagttcagt atgtttaaag tctctgtccc atcatttctt caacaaacct tgttcttgga
    26041 gaaactcctt ggctacttgc tttgctgact tgccttcaac accgacttgg tagttgagct
    26101 ggctcatctg gctttctgta atcttaccag ccaatgtatt aagaactctt tccaactctg
    26161 ggtgtttctt gagaagagct tctttcatga gtggagcccc ttgataaggt gggaagagtt
    26221 gcttgtcatc ttccaagacc tgtaaatcat aacgctccaa ttccgcatca gtcgaatagg
    26281 catccgtgat ttgaatatcc cctgactgaa ttgcctgata gcgaagagct ggctgcatag
    26341 tcgccacatt gagattgaga ccatacattg attgcaagcc cttatttcca tcttcacggt
    26401 cgttaaactc aagcgtaaag cctgccttca gctgcccttc cacttttttc aaatccgaaa
    26461 tggtcttcaa gccatattct tgagcaatct ttttcggaac agctacagca taggtatttt
    26521 gataagacat aggtttgaga taggctagat gatcctgctt ggcaattcca tcacgcgcca
    26581 cttgataaac ctgctctggc tcatgactca ccttgggtga tggttgaagc aaactttcag
    26641 tcaccgtacc ggtaaattca ggataaatgt caatatcacc ttttttcaga gcttcataaa
    26701 ggaaacttgt cgtcccaaaa ttcggtttaa cagtcgcagt catgctggta ttttcttcaa
    26761 tcagcaattt atacatatta gccaaaattt ctggttctgg gcctattttc ccagcaataa
    26821 tcaagttttc cttctctttt tgagccaaaa gggctggact ataagacaga cccagtaata
    26881 aagccatcaa ggcaaaacca gagaaaatcg tccgcaattt cgctttttcc attactttta
    26941 gtaggaagtt aaaggcaata gctagcactg cagaagaaag ggccccaatc aaaatcaaac
    27001 tggcattatt acggtcaatt cccaacagga taaaggaacc cagtccccct gccccaatca
    27061 aggtcgccaa ggtagccgta ccgataatca agaccgctgc cgtccgaatt ccagacatga
    27121 taacaggcat ggcaagtgga atttcaaact tcttgagacg ctcccatctg gtcatcccaa
    27181 aggcaatccc agcctcttga agactcggat caattccctt cagcccagta atagtatttt
    27241 gtaaaatcgg aaaaatcgca taaatcacta gagctgtcaa agccggcaag gtcccaattc
    27301 ccatcaaagg gataaagagc cccaacaagg ccagagacgg gatggtctgg aaaatacctg
    27361 caatctgcaa gacccagtcg gccagcttct catgatagcg aagaaaaaca gccaagggaa
    27421 tcgcaagcaa aatagctagt aacaaggtca aaagtgacaa ctgcaaatgt tgagatagag
    27481 ctgtcaacca atcactaaaa cgatcctgaa aagttgcaat taaattagtc atgaacacta
    27541 cctccaaaca agtctgctac aaagtctgtt gcaggcactt ttaaaattgt ctcgggattc
    27601 gctacctggc gaatttctcc atcctgcaag acagcaatac ggtccgccaa cttcaaggct
    27661 tcatccgtat catgggttac aaaaatcgtt gtcatcccaa actctttatg caattctttt
    27721 gtcagaacct gcaactgttt tctcgaaata gcatccaagg ccgaaaaggg ttcatccatg
    27781 aggaaaatct tgggctgacc aatcatagct cggacaatac cgacccgttg ctgttctcca
    27841 ccagataatt cactaggtaa gcgatgccca tactcggcta ctggtaaacc aaccttagcc
    27901 aaaagctctt ctgttttctt cgtaatttct tccttgctcc accccttcat ttcaggaatg
    27961 agagcaatat tttccgcaac tgttagattt ggaaaaagag caatagcctg taaaacataa
    28021 ccagtagaaa gacgaagttc acgctcatca tagtctttga tgcgcttccc atccatataa
    28081 atatttccat cagttggttc caaaagacgg ttaatcatct tgagcatggt cgtcttacct
    28141 gacccagaag gccctactaa aaccataaat tccccatcct caatctgtaa gttgacatct
    28201 ctcaagacat ccttttctgt gtagcgcagt gctacatttt tgtattcaat cattctttgt
    28261 cctcaattta aaacttccct cgattagtca agtcttctac cttaggcatg acttccttat
    28321 tatcccaatg ctccacaatt ttcccgttct ctaaacggaa gatatcgtac tgggcataag
    28381 caacgccatc aatctgagtc tgaccatagc taaccacata gtttccttgt cctaagagtt
    28441 ggaaaacaaa gtcaaaagtg acactatatt cagccacata gtttttataa gcagcacttc
    28501 cttgtccaat ctcatgatta tgctgaatca aatcgtctgc cacataatca ctccactgct
    28561 ctagctcccc attttggaaa atttctgtca agaaacggcg aaccagcttt ttattttctg
    28621 ctttcttatc caaatccttg atttcaaaat ctccaaaaat ttgatctagt tgatcatttt
    28681 caggtgttcg atagtagtca atgacatccc aatgctcaac aatacgacca ttctcatccg
    28741 cacggaaagt atccgtcgtc acccattgag cttctccacc attcagatat tgatgaacat
    28801 gaacaaagac cagattgcca tcctcaatgg tgcggacaat cttaatctga cgctctggat
    28861 gacgctcaaa gaaatctgca aagaaggctg caaatccttc tttcccgtca ggaacacctg
    28921 tcgaatgttg gatataggta tcccctacag actgggcttg agcctcagca actcgtccgt
    28981 cttgaatggc atggatgtat aggttgtgag catttttcac ttgttgtgac atattctaaa
    29041 cctcatttcc cttctctttc aaattcgcca aaattctttc ttgaaaacct tcaaattggt
    29101 gaatttcttc ctctgaaaat cctttgtaaa agatagtatc caatttctga ctgacacgat
    29161 gccccacttc tttctgggac ttgcctaact ccgttaaaac taaatacttc ttacgcttgt
    29221 cttttccaca cggactaaca attacaagct tttgttcctc tagctttttt atcatagtcg
    29281 tcagcgtatt attcgcaagc ccagtcgcaa gcgcgatatc tgtcgcagtt gcgcagccag
    29341 tttcactatt ccataaaacc gctaaaatct tgccctgttc acccctataa agagcctcag
    29401 gatcttgact cagtaacttt tgaaaaatcc gcccattcaa caaacgaata tgatgggcta
    29461 gcaaatgact atctttcata acacctccaa tttatttcga tgtcgaaatg aataaaataa
    29521 ttgtaacact catcgttcta actgtcaact atttcgattt ggaaataatt tttgataatt
    29581 attcacacca ccatactccg gctcaactaa cttttaacga gagtttctaa attccttcgt
    29641 cctccagtct acaaaagcct tccatccgta ctatcctatt ttttatgagg ggacacattt
    29701 ttcctatcag atcatttatt ttaaagatag aagtaaatca taattgcttc catctgttct
    29761 tttatagtat attgaagttg gactagggca ctgtatcttc taaaacattg atagaaagcg
    29821 atttgaattt cccaatcaat ttgttcgtct ttatagcatt tcgaaactgg aataggacac
    29881 catgactgct aaaagatttc tataaattca tttgatttcc ctaatcaatt tgttcatatc
    29941 ttatttcatt ccgctataat ttcaccttac cctatctttt tcgtagcacc cttcaaacag
    30001 cctatcccct accgtttgac gattcctcac ttcactccac ttccattaca gaagtttctt
    30061 cactactatg gtctcggctg acttctcatg attccttgtt actactattt gaacgctcac
    30121 gagataggtc ttataaaaaa tgctttgatc cacaatggaa tcaaagcatt ttaaaaagtt
    30181 cctcatacat aagtgcagaa gtcgcagttc ctctgtactt ggcttcttct cttttgataa
    30241 agcgagccaa gttgagcaac tcaggtgctg gatgtttggg atttaggagc aattcacgat
    30301 tgaccaggcc tgagagacga actgcctgca attgctcatt tgtagtaggc agttttttag
    30361 tagtctctag gagagcagca actaaatctt cactcaaatc atgtcgagca tgattgtaaa
    30421 gatcttttat aaggctttct aggtttggtt ctgccatccc taccacctcc cttatggttt
    30481 aataatgttt aatcaaatca accgttgaac gatccaattt cttcaccaag gcttgtaaga
    30541 aagcttgcgc ttctaggaag tcatccattg catagagggt ttggtgagaa tggatataac
    30601 gagcgcagac accgatagtt gttgatggga caccaccatt tttcagatga gctgcacctg
    30661 catctgttcc gcctttacca cagtagtatt ggtacttgat accagcttct tcagccgttg
    30721 tcaaaaggaa atccttcatc cctgggagaa gcaagtgacc tggatcatag aaacgaatca
    30781 aggttccatc tccaatcttg ccttgaccac cgtagacatc acctgctggg gagcaatcaa
    30841 ctgctaggaa gacttctggg tcaaacttgg ttgtagaggt atgagcgcca cgcagaccaa
    30901 cttcttcttg gacgttagaa cccagataga gttcattgcc gagtttttga cctgataaag
    30961 cttcagctag ctcgcttacc atgaggacac cgtagcggtt atcccaagct tttgagatga
    31021 tatttttttc attggctgtc aaaattgcag aactatctgg tacgatggta tcaccaggac
    31081 ggatgccaaa actttctgcc tcagccttgt ccgcaaaacc accatcaaaa acgatatcgg
    31141 caatggctgg catggttggt cccccctttc cacgagtcaa atgcggagga acagaacctg
    31201 aaatcacagg aatttcatga ccatcacgag tcaagagttt gaaacgttgg ctgctaacca
    31261 ccatggggtt ccagccaccg atttctacga cacggaaggt accatctggc ttgatttcgc
    31321 tgaccataaa accaacttcg tccatatgag aagcgaccaa gacgcgcggt gcatccacag
    31381 cttctgaatg tttgatacca aaaataccac ccaagccatc tgtcaccact tcatccacat
    31441 gcggtgtcaa cttttcacga agataagcac ggacaggcgc ttcatgacct gagactgcag
    31501 caagttctgt tacttcttta atttttgaaa ataatgttgt catttcagtt ccttctttct
    31561 ttcatccatt ttaccacttt ttataggaga aggatagtgg gaaggtggat ttctaagtta
    31621 gtatcttagt cctgctctat cttagaaaag gatagtattc tcttgcatgt agtgcaaaat
    31681 ctagtaaaca ttccaaaatt aactcgaata tttatttcca aacaaaaaac aatacaccat
    31741 caaagttgtt tggatttttc atgaaattta cagaaaatag ttgacttccc tttcttcttt
    31801 ctttaaatat atagttggtt gagtttggaa tagtacgctg tagctgctaa aacatttcta
    31861 gaaattaatt tgactttcct aatagagttg ttcatatctt atttcaattt actatagtac
    31921 aaaactagaa aaggaaaaaa tcatgaccaa aacaattctt gttacaggtg ggactagcta
    31981 cattggctcc cataccgtta aagctctttt aaatgctggc tataaggtgc atgtcctcga
    32041 taatctctcc acaggaaatc gagcggctgt ggatagtcgt gctagcttta aagaactgga
    32101 tgtttatgat gctagcgcct taaaggctta cttaaaagaa aatcagattg atgctgtcct
    32161 ccattatgca ggtgaaattg ttgtgagcga aagtattgaa aatccaagta aatacttcac
    32221 tgccaacgtt gctggtagga accaagttct caaagtctta tctgaagttg gcactcaaaa
    32281 aatcatgttc tcttcgactg cttctctcta tggaaataac tgtattgaca agccggcgac
    32341 tgaagatacc ctgatcgacc ctgtcaaccc ttatacagag acaaaactga tgggcgaacg
    32401 aatgatttac tggatggcca atcgctacga ctggaaatat gttattttcc gttactttaa
    32461 tgttgctggg gctgaaatgg atgcttcaaa cggtctgcgt gtgaaaaatc caactcacat
    32521 cattccaaat atcaacaaga ccgcattggg acaaaatgat agcttaaaaa tatttggaga
    32581 tgactacgat acacgtgacg gttcatgtat tcgagattac atttatgtct tggaccttgc
    32641 ataggctcat gttaaaggaa tgaactacct atttcaagaa gacagttctt ctcaaatctt
    32701 taacttagga actaaaaaag gctatactat caaagaaatc tttaaaactg ctgaagaatt
    32761 actaaattaa aaaatcccac acgagattgt tgctcgacgt gctagtgacc cagccagtgt
    32821 cctagcagat gcttcaaaag ctaaacaata tcttgattgg acggctagct actccctcga
    32881 agatattatt ttatcagatt aaggtaaaaa cattttagaa taggataaca aaggagaaag
    32941 tcttgttgct ctctccttgt tgtatttatt aaattgtcag aaattttatt gacagattag
    33001 aaaaataatg ttacatttat atccgcagat atctttcgat accaaatcta catgaaagga
    33061 cggggtatga aactttctca ttatttaatt ggcttacttc tactcctagt ctttctctct
    33121 attagcattg ggaccagtga tttttcatgg ggaaagctat ttgatttcga ccagcagacc
    33181 tggctcctct ttcaagagtc ccgtctccca agaactatca gtattctcct gactgcctct
    33241 agtatgagta tggcaggcct tctcatgcag actattaccc aaaatcagtt tgctgcaccg
    33301 agtacagttg gaacgactga agccgccaaa ctgggaatgg tgctgagcct ttttgtcttt
    33361 ccatcggcta gtctgaccca aaagatgctc ttcgcttttg tttcatccat cgtattcacc
    33421 ctcttcttcc tagcctttat gaccattttt actgtaaagg aaaggtggat gttgcctctg
    33481 attgggatca tctatagcgg gattatcggc tcagtcacag aagttatcgc ctatcgtttc
    33541 aatctggttc agagtatgac tgcctggacc cagggctcct tctccatgat tcagacccat
    33601 cagtatgagt ggctcttctt aggcctcatc atcctgataa ccgtttggaa attatcccaa
    33661 accttcacca tcatgaatct agggaaagaa accagcgaga gtttggggat ttcctactcc
    33721 ctacttgaaa aactggccct ctttctggtg gcgctaacga caagcgtcac catgattacc
    33781 gtgggtggcc taccatttct cggagttatc gttcccaatc ttgttcgcaa gtgctatgga
    33841 gataatctaa gtcaaaccaa actcatggtc gcactggttg gtgccaatct agttctggct
    33901 tgcgatatcc tatcccgagt tctgattagg ccctatgagt tgtctgtcag tctcttgcta
    33961 ggaatcatcg gtagtctcgt ctttatccta cttctctgga gagggggacg aaaagatgca
    34021 gactaaaagc aaacatacca agctcttctg gattctcatt attcttgcca tcggagcttg
    34081 tcttctctac ttttggccca tcactcactt gtcagccttt gcttggaagt tgcgttccca
    34141 aaagatcatc gtttatctct tggtagccat cgcgactggg atttcgacca ttagttttca
    34201 aaccttgacg gaaaatcgct tcctgacgcc tagtattttg ggaattgaat ccttctacgt
    34261 cctactacaa accctactac tggtttttga aagcaagttt cttcaacttg gcaaatcccc
    34321 tatcttagaa ttcctagtct tacttcttgt ccagtccctc ttctttctcg ccttacaagg
    34381 ttacttgaag acactgatga agcaagacct ggtcttcatc ctgctgatct gtctagcgct
    34441 cagaagtctc tttcgaaata tcagcacctt ccttcaagtc ctaatggatc caaacgaata
    34501 cgataaactg caaaatagtc tttttgcctc ctttcaacat cttaacactt ccatcctagc
    34561 catcggttct ctgatcatcc tcgctttgac aatctttttc tttcgaaaag cagtcgttct
    34621 agatgtcttg cacctgcaaa gagaaacggc tcagatattg ggactcgatg ttgaaaaaga
    34681 acagaaagag ctcctctggg gaatcgtgct tttgacctca acggccactg ccttggtagg
    34741 acctatggcc ttcttcggct ttatgctggc caacctcacc tacctgattg tcaaagacta
    34801 tcagcacaag ttactcttta tagtggccat tctggttgga tttattagct taaccttggg
    34861 gcaagccttg attgaacgag tctttgcact ggaaattcgt atcagtatga tcattgagag
    34921 tgtgggtggc ttcttattct ttatcttact atataggagg gctcgtcagt gaaactggaa
    34981 aacattgaca aatccattca aaaacaggat attttgcaag gcatttcgct tgaagtcagt
    35041 cctcaaaaac tgacagcctt tattggtcca aatggtgctg gaaaatcgac tctcctctcc
    35101 atcatgagca gactaaccaa gaaagatcag ggagttctca gtatcaaagg acgtgaaatc
    35161 gagagctgga attcgcaaga actggcccaa gaactaacca tcctaaaaca gaaaatcaat
    35221 taccaagcca aattgactgt tgaagaactg gtcagttttg gacgttttcc ctacagccga
    35281 ggtcgactta gatcagaaga ctgggaaaaa atccgagaaa ctctgaacta tttggaactg
    35341 accaacttaa aagaccgcta catcaatagc ctgtcagggg ggcaactcca gcgcgtcttt
    35401 atcgctatgg tactggccca ggatacggac tttatcttgc tggacgaacc actcaacaat
    35461 ctcgatatca agcaaagcgt cagcatgatg caaattcttc gacgactggt ggaggaactc
    35521 ggcaagacca ttatcatcgt cctccacgat atcaacatgg ccagtcagta tgcagatgaa
    35581 attgtcgcct tcaaggacgg tcaggtcttt agcaagggaa gcaccgatca aatcatgcag
    35641 gctgacctgc tcagccaact ttatgagatt cccatcacgc tagctgatat caatgacaaa
    35701 aagatctgta tctatagcta gtaacataaa agctcaagtt agagaacctt cagtctctta
    35761 atcaataaga tcaagagact ccctaaatcg ttatcacatt ttaaaaagga gaaattatga
    35821 aaacatccct taaactttat ttcactgccc tagtggccag cttcttgctc ctacttggtg
    35881 catgtagtac aaactcaagc actagtcaga cagagaccag tagctctgct ccaacagagg
    35941 taaccattaa aagttcactg gacgaggtca aactttccaa agttcctgaa aagattgtga
    36001 cctttgacct cggcgctgcg gatactattc gcgctttagg atttgaaaaa aatatcgtcg
    36061 gaatgcctac aaaaactgtt ccgacttatc taaaagacct agtgggaact gtcaaaaatg
    36121 ttggttctat gaaagaacct gatttagaag ctatcgccgc ccttgagcct gatttgatta
    36181 tcgcttcacc acgtacacaa aaattcgtag acaaattcaa agaaatcgcc ccaaccgttc
    36241 tcttccaagc aagcaaggac gactactgga cttctaccaa ggctaatatc gaatccttag
    36301 caagtgcctt cggcgaaact ggtacacaga aagccaagga agaattggcc aagctagaca
    36361 agagcatcca agaagtcgct actaaaaatg aaagctctga caaaaaggcc cttgcgatcc
    36421 tccttaatga aggaaaaatg gcagcctttg gtgccaaatc tcgtttctct ttcttgtacc
    36481 aaaccttgaa attcaaacca actgatacaa catttgaaga ctcacgccac ggacaagaag
    36541 tcagctttga aagtgtcaaa gaaatcaacc ctgacatcct ctttgtcatc aaccgtaccc
    36601 ttgccatcgg tggggacaac tctagcaacg acggtgtcct agaaaatgcc cttatcgctg
    36661 aaacacctgc tgctaaaaat ggtaagatta tccaactaac accagacctc tggtatctaa
    36721 gcggaggcgg acttgaatca acaaaactca tgattgaaga catacaaaaa gctttgaaat
    36781 aagccacttc aaactcaatt taatactcaa tgaaaatcaa agagcaaact aggaaactag
    36841 ccgcaggttg ctcaaaacac tgttttgagg ttgcagatga aagctgacgc ggtttgaagg
    36901 gattttcgaa gagtataaaa ttttgacatt ctaaaacgca tcctatcaag ttcactcaaa
    36961 cctgatagga tgcgttttta tcattttgaa atctatttac cccacctcat tccccttctt
    37021 gatttcgttt aagggaaaag tggtctggaa cggggtcctt acctgttttc gaccagggat
    37081 gacaacgtaa aatccgagcc aagcccatca ataccccctt aaaaccatgt ttttcaatag
    37141 cctgaatcat gtagttggaa caagtcagct caaagcgaca agagggtgga aagactggtg
    37201 agataaaacg ttggtaaaag cgcacaggcg ctattaaaat tcgtttcatt atttcttagt
    37261 tacagccatg gtgtgtagtt ggctgatttc ttttttatta agacgacggg attctcctgg
    37321 acggagtcct gtcaagtcta ggtgtccgaa acgagtccga gacaacttat ctacttggag
    37381 accaacagct tcaaacatct ttttaacctg atggttacgc ccttcatgga tggtcaactg
    37441 caccacagag cgatttttga ctgggtccac tttgagaatt tcataaacag ctggcttggt
    37501 tttcttacca tcaatctcaa gaccacgggt caaggggcgg agattgtcct tattggccac
    37561 acctttaaca cgcgcgacat aaaccttgtc aatctcatta cgagggtgaa tcatctcgtc
    37621 tgtaaagtcc ccatcattgg tcaaaatcaa gacacctgat gtatcccagt ccaaacgacc
    37681 cacagggtaa atacgttctt tgacattggg caagaggtcg acaaccgtct tgcgaccctt
    37741 atcatctgtc acactggaaa tcacaccgcg tggtttgtta agcagatagt aaaccttttc
    37801 ttcgttgtag ataggttgac cttcaacttc gaccttgtcg cctgacttga tagtggttgc
    37861 tagttcacgc accacttggc cgttaaccgt caccaagcct tgcttaatca gctcttctgc
    37921 ttttctccta ctggccacac ctgcgtgggc aatatactta ttgattctca tcttcttcta
    37981 tcctttcacc aaataattgg ctttcttggg cttgaatctc aagctcatca atcactggta
    38041 attcttctaa atggtttatc cccatgtaat ctaggaaata atccgtagtc acatagaggt
    38101 tggggcgccc caatacttcc tttttcccgt cttcctttat caggtcaaaa gcctgcaact
    38161 ttgccaaggc tccactcgag ttaaccccac ggatggcatc aatttctatc cgcgtaatcg
    38221 gctgtttgta ggcaataatg gacaaggtct caagggcagc ccgagacaag ctctggttga
    38281 taggcgcctt agagtattcc ttcaaaatct ctgcaaattg aggcttggtc accaatctat
    38341 aagcaccact tgtctcaatc aaagccaaac tggaatctgg gtccttttca tacttctggg
    38401 ctaattttcc taaactttgc tggatgcctg tcggtggcag agagaggagt tcagctaact
    38461 ggcggacccg aatcccatct tcacccgcta caaacaagag cgcttctatt tttgctaaag
    38521 tactcatctt tcctctctat caagtctagc tttgaggcac ttgactttct tccttctttt
    38581 ccatgagata gatatctcca aaactctcct cttgcacgag gatcagctcc tgggttttga
    38641 ttaactctag ggttgccaaa aagagggtga tgacctcttg gacattctgg gcttccttga
    38701 acaaatcctg caagcgcaat tgatctcgtc caatcaagga ttctttcaca ataatcatca
    38761 tgtcctcaat cttatactca tcccgcaaga tagtcgtgtg attttgtgca aactcctctt
    38821 ttttcttggc taggatattt gaaaaagcca aaaagaggtc aatggtcgtc ttgtcatgca
    38881 caagctccgc atcttcgtaa atcaactctg tcggcgcttt ggaataatac tgggcccgtt
    38941 cttggtgctt ggcttccaag tgctcaccca agagcttgaa cttgcgatat tcttcgattt
    39001 gagagaggag gtcctgctcc aggtcatccc ccaagtctgt cacttctgct accttcggaa
    39061 ggagtttacg actcttaatc agcatgagct gactagccat gaccatgtac tcacccgtca
    39121 cttccagacg catggcctgc agggttgaga cataggctag atactgttcg atgacttccg
    39181 taatgggcac atcgtagata tccatctggt acttagaaac cagatgcaag agtaagtcca
    39241 ggggtccttc aaaatctttt aatttaatat ccattatcta tatttttcta aggtcaggac
    39301 tgtttttaat cctaattttt ttgcaatttc gtacaaatcg accttgtttt ctatttgtct
    39361 tagaataaac tgttcacgta agacttgagc tgataaggat ggaaaacctt tctccttgac
    39421 aaaagattct aactgacgaa aggcccactg acgagaatag ggtttccctc ctctttcaaa
    39481 aagataggtc tgccccatca agggttccaa ttctgaaagc aaggccgtgg gaatggtgac
    39541 aatcctccgt tgggaagcct tgctgattcg caacacctga aaatccagat tgatgtccgc
    39601 aaccttgatg actaaaatct cactgggcaa gagccccatt tctatgatta agagcgctag
    39661 caagcggccc tctggatggt cgctttcctg ccaaaaagag tctaggtata gaatctctgg
    39721 cttttccgtc ttcttttcag cttgtttggc taattccaag cggtaaaagc tgtccacctc
    39781 tcctttttga tagagaaagt atagaaattg gttacaggcc gaaatctttc gcttctgggc
    39841 gctgattttt agattggcta gctgggcttg gtaaatcttg agactggtct cagaaatccg
    39901 ctcacctacc atgtctaaaa attgctccaa atcatactta taggactgct tggaattgac
    39961 agacaagccc tgcttttcct ctaaaaaggc tgaaatcctg tctctcattg gcatcgaatc
    40021 tcatattcct tactaaagtc atgcaagagg gcattaacgg ccttgaggat ggacttgcgc
    40081 gtaataatcc cttggaaaat accctctgca tccacaaccg gtaagaagga ctcatctact
    40141 agcttgtgca agacctccgt aatggtgaaa tcaggcgaaa caaccgctac gtccgttttt
    40201 gtcatatgaa cgatatccgt atccgccatg atttcttggc tcaagtcatg ctccatctga
    40261 taagccataa tatctctgag tccaatcgtc ccaacaaact gtttttcatc tgtcacaacg
    40321 ggaacacggg tataggtcat ctgactgagc aagagggtcg catgatccgc attgtgagta
    40381 tcaatcaaca cagctagatt tttagcaggg gtcaaaaaag tttcctcctg ccccaacaag
    40441 aaagtctcaa actccttggc aatcatcggc taaactcctt ggacaaacct ggatacacct
    40501 cgtgatctcg tgtcaaaaag tccactttga agtaactatc atcaatctcc acacgagcat
    40561 agagacattc tctgatggta cctcgtggtt gactgataga gcctggattt agaaagagga
    40621 tcttgccttc caaccaagca cttggcacat gcaagtgacc atagaggcag atagcggcct
    40681 cttcctcctg agcccagtag tccaactttt gaaagttgaa attgatgtca aacaagtgac
    40741 catgagtttg gataatcttg gtcgaaccaa gctcagtcac cagacgttct gggtagccgg
    40801 cgtagaagtc catgttccct ttaacaacgc ggatgccctc ccaaagtgga gaatccggac
    40861 gtagttcaga atcgccgtta tgaaaaacgg catcgacttt gcccacatag cgatcacgga
    40921 cttcttccac aatcaagcta tcgccatggg aatcgctcat tacaatgatg gtttgctttg
    40981 ccatgatgga aatacctcca aaagtttctt aacggctaag gcacggtgag attgactatt
    41041 tttttcttcc agggttaatt cagctgatga ctcacctgtc tctcctacaa ggaagagggg
    41101 atcatagcca aagccatttt cacccttagg ttcaaagtta atataacctg accagtctgc
    41161 ttcaacaact aaactttcct tatttgggct ggctacgact agggttgtgt ggaactgagc
    41221 cgagcggtcc ttgagttcaa agaccatggc caattcgtgc aagagtttgg cattattttc
    41281 acggtcagtt gctcccacac ctgcgaaacg agctgaccag acgcctggta agccaccaag
    41341 gacatcgact ttgagaccag aatcatctgc caaaaccatc ttgcccgtta attgagaaat
    41401 ggtttctgcc ttaaggcggg cattttcctc aaaggtcata cctgtttctg ctacttcagg
    41461 caggtcaggg tagtcattaa gattttccac atcgtagcct aacttatcaa agatagctcg
    41521 gaattccttg gttttacctt cgttacgagt cgcaatcaac aaggtttctc tgactttgct
    41581 tgtctcaaag aaatcatgaa cattgacccc ttctttaggc aattctacat acaagagttg
    41641 cccattttca accaagagca gggccccatg acgttgaata acttccaagt ttcgtcccat
    41701 ttcttgatta agcatatcta ccacaaagga gaacaaacgg taggtagaac catagcgtaa
    41761 aacagtaact gaaagcggga aaccatactc ttcatctcca aatattttgg agaattcaaa
    41821 cagaggaaaa tctgtctgat agtcgctcaa actgttaacg ccaccaaaaa tactataaga
    41881 cccaacatac cagtcctggt catccttata ttcataaatt ttatttgtca taattctaca
    41941 tgctccacat gaatctcttt ttccagccat tcttcaccaa tttgtgcaaa actttggcta
    42001 ctggctgttg tgtaaaaacg gtgatggagt ggtccagcat cgcgaccacg attgatttca
    42061 aaataattga gtaagactga gatatcccgt acgcactctg ccccactatc gatgagctga
    42121 acctttggcc ccatcacatt ttggataata gggcgaagga gtggataatg agtacagccc
    42181 aaaatcaggc tatccacctt tccaaccaag ggacgcaggg tttcatagac caccttcttg
    42241 gtaacactgg ttgacagggc acctgactca accaagggag caaacttggg acaggccaag
    42301 ctctccacct gtaagtcggg atccagatca tggattttct gacggtatat gtctgattgt
    42361 accgtcatgg gcgttccaat cactccgatt ttcccacctt gactggactt gatggctgcc
    42421 gaagctcctg gcaaaattac acccaagaca ggaatatcta gttgagcctt gatttcttcc
    42481 cagacgaccg cagtcgcagt gttacaagca atgacaatca ttttgacatc cttggtcaag
    42541 agaaagttga ccagctgcca agtatattca cgaatttgct cagcaggacg ggggccatag
    42601 ggcgcccgcg ccgaatctcc aatatagacg atttcttcat ggggaagctg gcgcatgagc
    42661 tcgcgcacaa cggtcaagcc cccgacaccc gaatccaaaa aaccaattgg tcgattatcc
    42721 atacagtctt ctttctagtc ttttttctga ttgatcgttc attatgattc cttgtactga
    42781 acgaactgac cgacagcttg atagaatgtc aactacctct ctcttaatca taatcaaata
    42841 tcaatagaat gcaaggaaaa agtctcatcc ctaaaccata accaacatag tgagaagtct
    42901 ggaactttca tcccagactt ttccttattt attttttctt tttattgtta gcaagggctg
    42961 ccttttgttg gcggatgatt tggtggtaaa cttgttgtac cttagcttcg cttggttttt
    43021 gaccatttgc actcaaaaga gtacgaactg cttcagcatt caaacgtggg ttgtcagcaa
    43081 attctttttc gatttgctta cgaaccaagt acattcctcc aagagctcct cctagaaaag
    43141 ctagcacaat caatacaatt gctaaaagta aatccatcat ttttctcctg tttctttttg
    43201 aatccctttc attataccac aaactagcca ccctgaccag tttgttctac actttcaggg
    43261 atggaataga cagcaaaaag aaccctgctt ttctgaaaaa gaggtctcct tgctaagttt
    43321 atactcaatg aaaatcaaag agcaaactag gaagctagcc acaggttgct caaagcaccg
    43381 ctttgaggtt gcagataaaa ctgacacggt ttgaagagat tttcgaagag tattaattta
    43441 cataaatagc cagtgtttga tagggtttga gtagaatttt ctcagacact tctgcatctt
    43501 catagtttga tatcaaaatc tgtccatttt ggtagactgc tggcaagtcg atttccactt
    43561 ctttagcata aaagttattg agcactagta acttttgatc ctcaaactgg cgttcaaaag
    43621 cgtagacttg tttgctatct tcaaaggctg gtttgtaact tccttctgaa atgattggca
    43681 tttccttacg cagtcgaatc aagtcttgat agaaggtgaa aatcggaccc tggatttcat
    43741 tttctacatt gatgtattta taggatttac cagctttcaa ccatggagtg cctgttgaaa
    43801 atcctgcatt ttccgaagca tcccactgca tgggaatgcg tgaattatca cgcgacttag
    43861 cttgaataat ctggaaggct tcttgctgac tctttccttc ttctaagagc gtctgatagg
    43921 cattaagcga ttcgacatcc acataatcag ccatagaatc atagtctggg tcaatcatcc
    43981 cgatttcttc acccatatag atataaggtg tcccacgtga caggtgaatg ctagccgcta
    44041 gcatggtggc tccttccttg cggaagtttt gaatatcgac aaaacggttc aaggcacgtg
    44101 gttgatcgtg attgttccaa aagagggcac tccaaccgtc tttatcactc atttccttac
    44161 cccaactatg gtaaagactc ttcaactctt caaaatcaaa gggagccaag gtccactttt
    44221 gtccatcctt atagtccacc ttgaggtgat gaaaattaaa ggtcatggat aattcctgac
    44281 gatcaggcga cgaatagagg acacagtttt ccatggtggt agaagacatt tccccaactg
    44341 tcataaagct atcgtcagat ccaaaagtgg cttggttcat catacgcaaa tagttatgaa
    44401 cgatgggttt gtctgtataa gctggcttcc cttcattttc aggacagtcc actgaaacct
    44461 cgtccttacc gatcaaattg atcacatcaa atcggaaacc tttgataccc ttgtcgcgcc
    44521 agaaattaac aaccttgaaa agctccttac ggacattgga attgcgccag ttaaggtcag
    44581 cctgggtctc atcaaatagg tgaagatagt atttcccagt atccccgaaa ggcgtccatg
    44641 cagaaccacc aaacttagac tgccaatctg ttggttggtc ttggatgaag aaaaagtctt
    44701 gataatactt atcaccagct agggctttct gaaaccattc atgctctgtc gaacaatgat
    44761 taagtaccat gtccagcata aagtcaatct tgtgctcttt accgacacac accatttcct
    44821 caaaatcagc catatcacca aaaagaggat ccactgccat ataatctgaa atatcgtaac
    44881 cattatcccg ttgagggctt ggatagaatg gattgagcca gaccatatcc acacctagtt
    44941 tggctaaata gggaattttt tcgataatcc cacggaaatc cccaataccg ttttcagtgg
    45001 tgtctttgta agattttgga tagatttgat agactacttt tcctttatca agtgtcatct
    45061 gtttctcctt ttctgataaa agggaggaag cagtcttccg tccctatttg tgctatttca
    45121 attatactca atgaaaatca aagaacaaac taggaagcta gccacaggtt gctcaaaaca
    45181 ctattttgag gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtattaga
    45241 ttcgtgtagc gaccatgaga gatgctccag cttggatcgt tgtcggataa gttccgggaa
    45301 tagtcgctgt ataagcatct tggttggtga tgataacagg agtttctgtc accagacctg
    45361 cagccttaat gacatccata tcaaaacgaa tcagttgctg accaactgta acgtgatctc
    45421 cttggactac aagactttca aaacctttgc catcaagacc tactgtatcc ataccgatgt
    45481 ggatgagcaa ttcaactccc tcgtcagaga caatgccgat ggcatgcttg gtagggaaaa
    45541 gaaccgtcac tgtcccatta actggagagg tcaactcacc ttggcttggt tcaatgacta
    45601 gaccttgccc catgacacct gatgcaaaaa taggatccgt cgcttgactc aattctttca
    45661 cttggccagt tagtgggctg ataatttcta ccgaagtaag ttctactggt tcatggttca
    45721 caaattctgc ttcttcttga gcaacgaatt ctgcctgcaa gttcgtatcg ccctctgttt
    45781 ttgtaaagag accagccttg cggaagaaga aagtcaagag cattggaaca acaatcgcaa
    45841 ctagcatagt tcctgcaaat ggcagcatgt attgaggttg aatagagaga atacctggca
    45901 aaccaccgat accaatagaa gccgcagtta cattaaaagt aacggataac atgcctgcaa
    45961 gggctgaacc agtcatccca gcaacaaatg gataaatata ttttacgtta accccaaaaa
    46021 gagctggttc tgtaacaccg agataggctg aaatggttgc aggaagtgaa acctgagcct
    46081 cacgctcatc atggcgatgc atgaaataat agacaaacac ggctgagcct tgagcaatat
    46141 tagaaagagc aatcattggc catagggcag tgccaccagc atccgcaatc aattgtgtat
    46201 caatggcatt ggtcatatgg tgcagacctg tgatgacaaa tggagcgtag agggcaccaa
    46261 aaattgcacc gaagagccat ttaactggac cagttaaacc tgccaagaca actgatgaaa
    46321 gtccttgtcc aattgtccaa ccgattggtc ccaaaacagt atgagccaaa atcaaggctg
    46381 gaatcaatga caagaaaggt acaaaaatca tagaaatgac ttctgggata tgcttgcgcc
    46441 agaagatttc aagataagac agactcaaac ctgcaagcaa ggctgggata acttgggctt
    46501 ggtaaccgat acgattaaca gtaaaatagc caaaattcca aacccagttt gccgcgatat
    46561 cagctgctgg cgttgaagca accgcatagg cattgagcaa ctgaggcgat accaaacaga
    46621 ttccgagaac aattcccaaa atttggctgg ttcccatctt acgagaaaca gaccaagtaa
    46681 tccctactgg taagaactgg aagatagctt caccaggcaa ccagaggaag tgattgacac
    46741 ctgcccaaaa ctgagaggat tctgtgatgg tcttgccatc caacatcgac caatggacac
    46801 cttccaagac attacggaaa ccgaggatca atcctccgac tatcaaggct ggaataatcg
    46861 gagtaaaaat ctccgccaga gtggtcataa cacgttggac cacgttttga ttactcttag
    46921 ctgcagactt ggctgcttct ttggaaacac cctcaatacc tgaaacggct gtaaaatcat
    46981 tataaaagat gggcacgtca tttccaatga ttacctgaaa ttgacctgca tttgtaaaag
    47041 ttcctttaac agctggaatt gactcgatag ctttaacatt agccttctta tcatctccta
    47101 aaacaaagcg catccgtgtc gcacagtggg tgacggcagt cacattttct ttgcctccaa
    47161 ttgcctgaag cagatctttg gcttcttgtt caaattttcc catttgattc tccttatact
    47221 tgtcaaagca agtttgattt gataagtata ttgtaaacga taccaaactt gtctgcaact
    47281 tgtttggtat aaaaagggtg tttttttgta aattttctag cacttgtatg gtaaaataga
    47341 tacaggtgtt cattaaacta gactaaaaac ctatttaagc aggcaaaatg aagaaatacc
    47401 aacaattatt taagcaaatc caagaaacca ttcaaaacga gacttacgct gtcggagatt
    47461 tccttcctag cgagcacgac cttatggagc aatatcaagt gagtcgtgat accgtccgaa
    47521 aggccctgtc tctcctccaa gaggaaggat tgatcaaaaa gataagaggg caaggttctc
    47581 aagtcgtcaa agaagaaacc gtcaatttcc ctgtatccaa cctaaccagc taccaagaac
    47641 tagttaaaga acttggactg cgctctaaaa ccaacgtggt cagtctggac aagattatta
    47701 ttgataaaaa atcctcactg ataaccggtt tcccagagtt tcggatggtt tggaaggtgg
    47761 tccgccagcg tgtggtggat gatctggtat ccgttctgga tacagactat ctggatatgg
    47821 aactaattcc aaatctcact cgccaaattg ctgagcagtc tatctattct tatatagaaa
    47881 atggcctcaa actccttatt gattatgctc agaaggaaat caccattgac cactcaagcg
    47941 accgagacaa gattctcatg gacattggca aagaccctta tgtcgtttcg attaaatcaa
    48001 aagtctatct ccaagacgga cgccaatttc agtttaccga aagtcgccat aagttagaaa
    48061 aatttagatt tgtagatttt gcaaaacgca agaaataaaa gactgagaca ccagatctca
    48121 gcctttttcg gctctataat atttgtagtg ggtaac
//
LOCUS       DAVLMQ010000011        45772 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000011 DAVLMQ010000000
VERSION     DAVLMQ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45772
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.011"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(564..2291)
                     /gene="ezrA"
                     /locus_tag="VXF95_000753"
     CDS             complement(564..2291)
                     /gene="ezrA"
                     /locus_tag="VXF95_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HEV1081335.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(2373..4319)
                     /gene="gyrB"
                     /locus_tag="VXF95_000754"
     CDS             complement(2373..4319)
                     /gene="gyrB"
                     /locus_tag="VXF95_000754"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HEV1081336.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEVVGDTDRTGTTVHFTPDPEIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(4334..4897)
                     /locus_tag="VXF95_000755"
     CDS             complement(4334..4897)
                     /locus_tag="VXF95_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1081337.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLVLYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(4982..5536)
                     /locus_tag="VXF95_000756"
     CDS             complement(4982..5536)
                     /locus_tag="VXF95_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HEV1081338.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGNLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYRDVFGKNQ"
     gene            complement(5547..6770)
                     /locus_tag="VXF95_000757"
     CDS             complement(5547..6770)
                     /locus_tag="VXF95_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1081339.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVSLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(6807..9257)
                     /locus_tag="VXF95_000758"
     CDS             complement(6807..9257)
                     /locus_tag="VXF95_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HEV1081340.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKTAASLELRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQSLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEAKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(9457..10386)
                     /locus_tag="VXF95_000759"
     CDS             complement(9457..10386)
                     /locus_tag="VXF95_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1081341.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDLLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARSLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            10526..10813
                     /locus_tag="VXF95_000760"
     CDS             10526..10813
                     /locus_tag="VXF95_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HEV1081342.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(10847..12181)
                     /gene="ciaH"
                     /locus_tag="VXF95_000761"
     CDS             complement(10847..12181)
                     /gene="ciaH"
                     /locus_tag="VXF95_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HEV1081343.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(12171..12845)
                     /gene="ciaR"
                     /locus_tag="VXF95_000762"
     CDS             complement(12171..12845)
                     /gene="ciaR"
                     /locus_tag="VXF95_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HEV1081344.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(12954..15500)
                     /locus_tag="VXF95_000763"
     CDS             complement(12954..15500)
                     /locus_tag="VXF95_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HEV1081345.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(15623..16063)
                     /locus_tag="VXF95_000764"
     CDS             complement(15623..16063)
                     /locus_tag="VXF95_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HEV1081346.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16038..16907)
                     /locus_tag="VXF95_000765"
     CDS             complement(16038..16907)
                     /locus_tag="VXF95_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HEV1081347.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQEFVKDYLDTICSFYLGKEVWYRFSELTNTEANCLVGTREFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSLIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLDRILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(16885..17385)
                     /locus_tag="VXF95_000766"
     CDS             complement(16885..17385)
                     /locus_tag="VXF95_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1081348.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKARGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVISYSNPRIYDVFVREELTNFMVHHVMALYDVEMNESAPQV
                     TTSEAVSDGANDSLGYIWMDIQEITEENASPLVLKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(17396..18094)
                     /locus_tag="VXF95_000767"
     CDS             complement(17396..18094)
                     /locus_tag="VXF95_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HEV1081349.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGFQVYGVDQGENPLLEGDF
                     HFLQRDLTLDLEPIFGWCPQVDVLCNTAGVLDDYKPLLEQTAQEIQEIFEINYMTPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEVAEVSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18087..18323)
                     /locus_tag="VXF95_000768"
     CDS             complement(18087..18323)
                     /locus_tag="VXF95_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HEV1081350.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(18423..19349)
                     /locus_tag="VXF95_000769"
     CDS             complement(18423..19349)
                     /locus_tag="VXF95_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HEV1081351.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCKLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSRAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(19424..20239)
                     /locus_tag="VXF95_000770"
     CDS             complement(19424..20239)
                     /locus_tag="VXF95_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081352.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LHYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVIGIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFLLFRGFKKIKWSEV"
     gene            complement(20243..20563)
                     /locus_tag="VXF95_000771"
     CDS             complement(20243..20563)
                     /locus_tag="VXF95_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1081353.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
     gene            complement(20815..20895)
                     /locus_tag="VXF95_000772"
                     /pseudo
     CDS             complement(20815..20895)
                     /locus_tag="VXF95_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(20939..22936)
                     /gene="metG"
                     /locus_tag="VXF95_000773"
     CDS             complement(20939..22936)
                     /gene="metG"
                     /locus_tag="VXF95_000773"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HEV1081354.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEIAYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(23060..24319)
                     /locus_tag="VXF95_000774"
     CDS             complement(23060..24319)
                     /locus_tag="VXF95_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081355.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKFQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNVDEIANIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(24321..25022)
                     /locus_tag="VXF95_000775"
     CDS             complement(24321..25022)
                     /locus_tag="VXF95_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081356.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(25006..26205)
                     /locus_tag="VXF95_000776"
     CDS             complement(25006..26205)
                     /locus_tag="VXF95_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HEV1081357.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTALKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVARADRHINELNQARNEAASAPAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            26470..27816
                     /gene="gor"
                     /locus_tag="VXF95_000777"
     CDS             26470..27816
                     /gene="gor"
                     /locus_tag="VXF95_000777"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HEV1081358.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNRESYIDRARSSYDGSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RTNLPLHTHKVPVKLEKTTDGITIHFEDGTSHTASQVIWATGRRPNVKGLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFASMYSACTRNRQESRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMGATKADFDATVAIHPTASEEFVTMR"
     gene            28013..28549
                     /locus_tag="VXF95_000778"
     CDS             28013..28549
                     /locus_tag="VXF95_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HEV1081359.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALVVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            28605..28685
                     /locus_tag="VXF95_000779"
                     /pseudo
     CDS             28605..28685
                     /locus_tag="VXF95_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(28754..28969)
                     /locus_tag="VXF95_000780"
     CDS             complement(28754..28969)
                     /locus_tag="VXF95_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HEV1081360.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PNHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            29067..29387
                     /locus_tag="VXF95_000781"
     CDS             29067..29387
                     /locus_tag="VXF95_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081361.1"
                     /translation="MRHKFQQVLDKIHDFLNGHDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(29418..29756)
                     /locus_tag="VXF95_000782"
     CDS             complement(29418..29756)
                     /locus_tag="VXF95_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081362.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(29768..30487)
                     /gene="trmD"
                     /locus_tag="VXF95_000783"
     CDS             complement(29768..30487)
                     /gene="trmD"
                     /locus_tag="VXF95_000783"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HEV1081363.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQAYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(30477..30995)
                     /gene="rimM"
                     /locus_tag="VXF95_000784"
     CDS             complement(30477..30995)
                     /gene="rimM"
                     /locus_tag="VXF95_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HEV1081364.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(31026..31814)
                     /locus_tag="VXF95_000785"
     CDS             complement(31026..31814)
                     /locus_tag="VXF95_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1081365.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADVVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKCQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDEYGPELYLKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFEDVSIEAHIPVFVFCQP
                     YREKEYRESEYWTSNTKLILGGNHHYLQWSESEKIAAIIRELSE"
     gene            31954..32163
                     /locus_tag="VXF95_000786"
     CDS             31954..32163
                     /locus_tag="VXF95_000786"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081366.1"
                     /translation="MLVINDCGFVFLKDSLGKVNMLDSSNSDGVVNDISQFSGKFLVR
                     ILSLLFDQSAYSKPRLLLRLPPLTS"
     gene            complement(32391..32630)
                     /locus_tag="VXF95_000787"
     CDS             complement(32391..32630)
                     /locus_tag="VXF95_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HEV1081367.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(32650..32922)
                     /gene="rpsP"
                     /locus_tag="VXF95_000788"
     CDS             complement(32650..32922)
                     /gene="rpsP"
                     /locus_tag="VXF95_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HEV1081368.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33092..33289
                     /locus_tag="VXF95_000789"
     CDS             33092..33289
                     /locus_tag="VXF95_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081369.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKRNMDLLVDD
                     SLAGDIILLWRIQFGTFTTET"
     gene            33768..33980
                     /locus_tag="VXF95_000790"
     CDS             33768..33980
                     /locus_tag="VXF95_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081370.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEDFQDDDEIPTII"
     gene            34063..34866
                     /locus_tag="VXF95_000791"
     CDS             34063..34866
                     /locus_tag="VXF95_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HEV1081371.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQNSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(34922..36463)
                     /locus_tag="VXF95_000792"
     CDS             complement(34922..36463)
                     /locus_tag="VXF95_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1081372.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMKMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQAKNLQIGY
                     DRPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(36465..36947)
                     /locus_tag="VXF95_000793"
     CDS             complement(36465..36947)
                     /locus_tag="VXF95_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1081373.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVCFCFTPQEQSTVGVGTPGIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNVLNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            complement(36947..38032)
                     /gene="rlmN"
                     /locus_tag="VXF95_000794"
     CDS             complement(36947..38032)
                     /gene="rlmN"
                     /locus_tag="VXF95_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HEV1081374.1"
                     /translation="MKPSIHSLAHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQRIVQESADGTVKYLFELPDGMLIETVLMRQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERVSHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHIMVSTSGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKLSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGVNCVVRQEHGT
                     DIDAACGQLRSNTMKRDRQKAVAAVNP"
     gene            complement(38053..38583)
                     /locus_tag="VXF95_000795"
     CDS             complement(38053..38583)
                     /locus_tag="VXF95_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HEV1081375.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKGQRHFVIRQK"
     gene            complement(38740..39345)
                     /locus_tag="VXF95_000796"
     CDS             complement(38740..39345)
                     /locus_tag="VXF95_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HEV1081376.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            complement(39518..40555)
                     /locus_tag="VXF95_000797"
     CDS             complement(39518..40555)
                     /locus_tag="VXF95_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HEV1081377.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQVLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKAFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKADSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            complement(40589..41524)
                     /locus_tag="VXF95_000798"
     CDS             complement(40589..41524)
                     /locus_tag="VXF95_000798"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HEV1081378.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            complement(42077..43267)
                     /locus_tag="VXF95_000799"
     CDS             complement(42077..43267)
                     /locus_tag="VXF95_000799"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HEV1081379.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKTKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            complement(43482..44825)
                     /locus_tag="VXF95_000800"
     CDS             complement(43482..44825)
                     /locus_tag="VXF95_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1081380.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIAGSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQLMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            complement(45205..45756)
                     /locus_tag="VXF95_000801"
     CDS             complement(45205..45756)
                     /locus_tag="VXF95_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001852542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HEV1081381.1"
                     /translation="MTYRFESATADNNLPAEVLSLLPQSGTYTTSSSVAIAFVPEAPM
                     PVEVAVANGTWTFLGYQEVEEGSNLTFVGKWVFEAKQDPSPQPQPAPTPQPAPQPNPV
                     PPVNPGGEQGTDNNQADRHQSEQPRKPEENPPAQGPAGEKEKQATLPNAGSTAPLSLT
                     GLVTSSLLAGLAVLLLGRKRKDD"
BASE COUNT        13539 a        10012 c         8277 g        13944 t
ORIGIN      
        1 ttggatttct tctttagttg attttatatt actattatat aatacttttt tattttagtc
       61 tagtataaat agcgagaaat atctatccta tcttctagaa tgtcttccaa acgagaaaac
      121 tctcgtaaac aaagaggttt tagaggccta tttaccgtgg gactaaagtt gtacaagaaa
      181 agtgcaaata agaaatctcc agattaggaa ctatccgtga gttctctagt ctggagattt
      241 ttcaatagac ttcgttattg gacggttacc aagttactca aagtacagat ttgaagctgc
      301 agataagact gacgaaatca ctttaatact aaatgaaaat caaaaagcaa actaagaagc
      361 tagcctcagg ctgtacttga gtacggtaag gcgacgctga cgtgatttga agagattttc
      421 gaagagtata aaacactgtt ttgaggtggt ggataaatcg gctgggtaaa aactcaatct
      481 caggagaaaa tgaagtaaat ctccccacaa ctatagaaaa agatttgatt ctgctcctca
      541 cacaataaaa tctttttctt ttattaaaaa cgaatcgttt cacgtgtttt ctcatatgag
      601 gtaacaaagc gattggttac accaggctct gccacttcca atgcttgaga aatcttgtca
      661 aatgaagcgt gataatcaaa ttctttttca aaaatatcta aagcttcgtt aaatgcttct
      721 tgaatgcgtt catcaaatga gcgatagcgg ttagaatatt gcaagagttg ctctgtcaaa
      781 gttgcatatt gtacaatatt ataagtttcc gtttctaaag cttccatatc attcgttgca
      841 atttcaagaa ctcgggtaac agattcaatg ttaatcattt tttgttctaa ctcaaccatt
      901 aaatcctcgg tattattgct tgccgtaaag aataacttca agaaagtttg tggaatacct
      961 ggcagattgc gtttttccat gtatcgcttg atagtatgga gacgattgac ataaacattg
     1021 gccttttgac gtgcattaat atcatctttc tcaatttgtg tcaggcgctc actaactgaa
     1081 atttgctcat cttcaatatc ttttagttga gtttgtaaat cctcaagatt ttcttcaaga
     1141 actgaataag cttgggttgg ttcttcttga ttcgaagtta cctcaacaat agctgcctca
     1201 aaactctcta attctgtctg aatacgacga acatggcttg cagctgtctc aggaagtaaa
     1261 taggtcttgt tcaaacgtgc aatatcttct cccaataaag tattattctc tttcatatgt
     1321 tgaaggtaag ttggaagagt tgcaagtaga ttttccacta ctttctgagc agcaatttct
     1381 cgagtaaaaa tatcatacaa ggcattgatt tcctcttgtg cctgtccatt ctcatattca
     1441 gcattatcca attccaactg acgaatattc tcttggtttt tcttgaatgc ttcataaagc
     1501 aagtggaaac gcgcttcaat atccgtttca acaaaatgat aattagcatc aattagttta
     1561 cgataaccgg cttccaaatc ctgtaattga tctggcaatt ctgtagaaag cgtcgtaacc
     1621 aaggctggaa cacgatccac aatatgactt aaggccaaaa tgtgattttc tgtattatcc
     1681 aaaatcactg cggcttccac agggtcaccc gatgaattca aggttacaaa ttgtgaaaat
     1741 tcagattgga tattttctaa ttgtttttca atttcatcca aggcttgacc atactgttct
     1801 gaattttcag caactctatg ctgaagttcc tcaaataaat ccaaagcatg aagaacacga
     1861 ccactatttt tagattcttg cttctctaag tctgccaaag cattgcgaat tgccgcaata
     1921 tcttcttcaa tcaaagtaat ttgactctca atttggtcaa tttgatgact ggccttgaga
     1981 aaacgaaatg aatggttata gccttctgct tcaaagagat tattttcaat atcggcaaaa
     2041 gagttgagag ataaatcgac ccatttttga ttccattcac ggaaagctac ttgactttgt
     2101 ccaatcaagt gcatattttt tacagcttct acttcatcat ttactggaag attgtatagt
     2161 tcttcttttc tttcttctag cgcctctaat ctcccctcgt ttcgcttacg tagaaagatt
     2221 gccactacat aagccagaac taaaatgact gcaattgcaa ccattaaata aattagttgt
     2281 ccattagaca tatcaaactc cttttttact tgaaacaatc gtaacgatta tatcatattt
     2341 tttagaccaa gggaactact tctccctatt ttttagacat caagtgtact atagacagca
     2401 ttttcttcga taaactcacg acgaggctct actcgatccc ccatcaacat atcaaagatt
     2461 ttatctgctt ctgcagcatc atctacagaa actctagcca tcaagcgatg ttcgggatcc
     2521 atggttgttt cccacagctg atgatcgtcc atttcaccta gccccttata acgctgaata
     2581 gtcggtttgg tacgaccttc actataacgg gctaaagctt cttggagttt gatttcttga
     2641 tctgcacccg gctggatata ttctttaatc tcgcttccaa ccttgacacc atagattggt
     2701 ggttgggcaa tataaacata tccagcttct aggattggtt tcatataacg ataaatcaag
     2761 gttaaaagaa gggtacgaat gtgggctcca tcgacatcgg catcggtcat caaaacgagt
     2821 ttttggtaac gggctttcga aacatcaaat tctgcgccaa atcctgttcc catggctgtg
     2881 aaaagactac gaatttcttc gttggctaga atcttatcca tacttgcttt ttcaacattc
     2941 aaaatcttac cgcgaattgg aaggatagcc tgaaactcac ggttacgacc agatttggct
     3001 gatccaccag ctgagtctcc ttcgacgatg aagagttctg tttcagcagg gttattagaa
     3061 gaacagtctg ctagtttccc tggaaggttg gaaatttcca aaccagattt tttacgtgtg
     3121 acttcacgcg cacgcttggc agccacacga gccttggcag ccaaaattcc tttttctacg
     3181 atacgtttgg caatctgtgg attttccatg aggaaatcgg agaaggcttc actgaagagg
     3241 cgattggtaa tcttgaccac ttcgctattt cccaatttgg tcttggtttg tccttcaaac
     3301 tgtggatttg ggtgtttaac tgagataact gcagttaagc cttcgcgaac atcttcccct
     3361 gttaaattat cttcattgtc tttcagtaac ttattcttac gagcataatc attgataaca
     3421 cgagtcagtg ccgtacggaa accttgttca tgcgttccac cttcatgggt atgaatatta
     3481 ttggcgaaac tcatgacatt ttcatggtaa cctgttgtgt actgcatggc tacctcaact
     3541 gtaatatcat ccatctcacc gtctgtatag attggtgtat caaagattac atccttgttc
     3601 tcgttgatat attcaacgta actagcaatc ccaccttcat aatgataatg cttggtttgt
     3661 tccaaacctt ggcgcttatc agtgatagaa atttgaagac cgcgatttag aaaggccaac
     3721 tcttgaatcc gtttatttaa tttatcaaaa tcaaagattg ttgtttcagt gaaaatttct
     3781 gggtccggtg tgaagtgaac cgttgttcca gttctatctg tatccccaac cacctcaagg
     3841 tctgcaacaa catgaccacg acggtattct tggtaatgaa tcttaccgtt tttatggaca
     3901 tgaacgtcta attgagtgga aagggcatta actactgacg accccacccc gtgaaggcca
     3961 cctgaaacct tgtatccacc accgccgaac tttcctccag catgaaggac tgtaaagacg
     4021 gtctcaacag caggacggcc tgttttttcc tgaatatcga ctgggatacc acgcccatca
     4081 tccacaacag taatcgaatc atctggctca ataaaaactt gaatatggct ggcaaatcct
     4141 gccaaggcct cgtcaattga gttatcaaca atttcccaga ctagatggtg aagaccttct
     4201 tttgaggttg atccaatgta catccctgga cgcatacgaa cagcctctaa gccctctaaa
     4261 acttgaattt gactggcatc ataatcctgt gcctgcagat ttttgatttc ttctgtcatc
     4321 ttattccttt ttcttatatg tctaatactt gtcttaaatt cacgatactg gtaaacaagt
     4381 gggtatcaag tcctgcagct tgacctgctt cgatatcaat cggccgatca ccaatgacaa
     4441 gaccagagct aatctgatac ttttctctta aataaagcat ggattcggga tttggctttc
     4501 tcttaaagcc tgagctagaa gtcaccactt ctgtaaaata agctgctata gaggtttttt
     4561 ctaaaatttc caaaacctga tcatttcgat gagagaccaa aaaatgacgg ccaccttgat
     4621 ttgaaatgac ttccaatagg tcagaaactc cttcaaataa aatcgggtgt tcaagctctc
     4681 tggcttcatt ttccttgtac ttttctaaaa aattctctaa attgggagcg aatgtctcaa
     4741 tcgcaaaagg agtagaaacc tttaaagctt gatagacact gtcatggtct tgtgtgatac
     4801 catacagtac caatgtttca acaaatgcag ctgttgaagt ttcataatta tccagtaaag
     4861 ttccacctaa atcccagatg taatcgtgat atttcatacc cttcattata gcattttttt
     4921 atgaaaaaag cgatgatttc cctgagtttt ccacataaaa aacgagagaa taactcccgt
     4981 tttactgatt tttaccaaag acatctcgat agagcattcc tgttcgtaaa ctctctgcgt
     5041 cccctcctag ttgctccacc aactcgtagg caaaggcaag ggctgttgaa ggaccccgac
     5101 tggttgtcaa ctgaccatct accactactg tttccttgac gtagtgacca tcaaggattt
     5161 gctcttgaac gccgtcataa caagtgtatc gcttattttt caatatctct gcttgattga
     5221 gggcaattgg tgccgcacaa atggctgcta gtttcttccc ttcttgctcg aagctttgca
     5281 attcttgaat caaggtctga ttatcacgta aatgtgcaga accaggcata cctccaggaa
     5341 gaacaatcat atcatagtct gataaatttc catcaaagac atgatctgct cttacttgga
     5401 ttgcatgcga acccgttact tgctcttcaa aaccaaccat atcacatgtg atattggctc
     5461 gacgcaagac atctacaact gtcaaggctt caatttcttc aaagccctga gctaacataa
     5521 ctgctacttt taccatgatt ttctccttat ttaatttgtt ttaatacaac ctttttccgt
     5581 ttgaatggga cttttccgct cttttcttca gctagattag tctggtaact catcgataaa
     5641 agcaaaccaa caccaatcag attactgata atagctgatc ccccttgcga aatgaaaggc
     5701 aagggaatcc ccgtcaaagg aagtagtcca gtcacagcac cgatattctc aaagatgtgg
     5761 aagagcaaca tcataatcaa acctgtggaa atataagtgt agaactggtt atttgattta
     5821 agagtaatct tcaacatacg gtaaatcaac atgagataga gggcaataac caggacagag
     5881 ccaataaagc caaaatcttc tgcaataacc gtaaaaatca tatctgactc tcgaactggg
     5941 ataagcagat tcgaagcatt aaatccctga ccaaataagc caccactccc aatggcaatc
     6001 tgcccttgag cctgctggta agtcgttgtt tgggcaaact caaagggatt gagccaagcc
     6061 aaaatccgat tgatttggta ggtcggcatt ccaatctggt gaagaaaagc tcgtccgtcc
     6121 ttgctaataa agatagctaa gaaaccagca actcctgtta cagcagtcac aaatactggg
     6181 ataataattt tccaagaaac ccctgataat aaaacgattc ctgagaaaat ggctacaaaa
     6241 accaaagccg tccccaagtc actttgaagt gctaaaagaa ctaggactgg aatggtaaag
     6301 agaatcatcc agaaaattaa caaaaagtcc agcgaaaccg tgcgtctcca ttccttatgt
     6361 ttctttgtaa attggacaat gacacgagcc aacatgagga tataggatat cttcataaat
     6421 tctgacggtt gaaatagggt aattccattt attgataccc agtttttggc acccgttgat
     6481 gcaactaagc ttggattata aaatacaatc ggcaagatca taagtcccaa gcctaaaata
     6541 tatagaaagg gggtcacctt ccaaagaaat tctgtattaa agagcatgac cacaaaacca
     6601 atcacaagcc ccaaggcaat ccaggcgacc tgctgcccta aaatgggcag aatattattg
     6661 ggataatcat gactaacggc tatatagata gccaccacac cgatgaccag tagaaaaaat
     6721 actggcaaga gcaaactgta atcgactctt gagtcgagag aacgtttcat atatactaac
     6781 cttatacttt catacaatac tatttatcaa agttcattaa aaaatctatc aatagcctcg
     6841 tcaacttcgg atcgagagat ggttttaaca gtcgcttctt ctgctagaga tgctactatt
     6901 tgtttgccgt atcgttttcc gacgattctc ctatccaaaa taagagttaa ggaacgttgg
     6961 tattcacgtc tcatacttct tcccaaagcc tgttttaaac gaataatggc cattggcaat
     7021 tgataatcat aaaaggcatt tttcccttct tgattcagtt cttgattaat ctttttcgtc
     7081 aagggttctt gaggattttg gaaaggaagc ctcggtacaa cttgaatcac aaaaggatgg
     7141 cttgaaaaat caactccctc ccagaaactt gctgcaccaa gcaagatttg ttgttcacct
     7201 ttttcaaagc gtttctttag ctgatgaaca tccccatttt tatactgggc caagtggcta
     7261 actgtaagta aatccgatac tgctagaagc atgtctttag cggtaaagag aaccaaaatc
     7321 ggttgctgga aagcttgaat ttccactagt aaagcagcta cctctctggc atagacttct
     7381 aaggaggttt ctgttaccag agggaaatct ttgaccataa ccacttcttg ttcctgtttt
     7441 ccccgagatt caatcttgac aaatttggct tcaggatagc ctaaaaggtc tgccaaagaa
     7501 accctctgac taatctcaag agtagccgat actcccaaga cttggcaact ctcaggaagt
     7561 aaagaggaca gaagagtacg gcctgatttt gtagaagaaa tctgaatttt cttttgactc
     7621 gtttcagtta cttcaagcca gtaatcacct tcagctgtaa aatagcgaac cagctcatca
     7681 aagccttcta cttctaattc tgaaaaatac tgatggagat tgtccagaga atctaagata
     7741 tttttcctag atttaccaga ctgaaattgt tctatcaagt agagacactc aaagcgaata
     7801 ctttctagta tccgttgttg aaccctgttt tcttccccta ctaaagcctt atcaattaaa
     7861 tcgataatag attgtatatc gtaggtctct tgaagcagat tttctagagc taacaaaatc
     7921 ttttggactt catcaataat cagtaaacgg tcactgacaa attcaggatt atcttcaagt
     7981 ctggtcacga gataggcatg attagtcact aaaagcttgc aagtctctgc cctttcttga
     8041 ctacgtttcc aaaaatcttc cgtcacaaat aagctctggg atgataaatt cccatcatga
     8101 cgaaggtctg ctagaaaatg ttggtaacgg tagagttgcc cgatttcatc caaatctcct
     8161 gtctctgtct cagtaagcca gaccaagact tgcattttaa agcgtctaaa taagcgattt
     8221 tcatcatttt cctgcaagga atgataaaag gcatccaact tcagataatt ttgtggtccc
     8281 tttaagctat gaatatctgt atggaacact tccttgagac gtttaccttc ttcttccatg
     8341 atttgatttt gaagaatctt tgtcggaaca ctaagaacaa tttgtcgctc tttggattga
     8401 gataaagcgg gtaagagata gccataggtt ttcccaatcc ctgtcggcgc ttgaatcaga
     8461 gagacaggtt catctttcaa tagcaagcca acctctttag caaaactttc ttgttcctcc
     8521 ctcacttcaa ggttcaacag agaaatattt ttagaaaagt cttgagatag ttttcgtagc
     8581 tccagagaag ctgccgtttt cttaaaatac agaccttgaa cttggaccaa gtctggagaa
     8641 ctcaggatag attggttgcg ataagtttcc tcaataacca ggtaggactc atataggaga
     8701 gcgtcagcca tttccagcaa gcgttccaag agacctttag gaagctgggt catcttttcc
     8761 cgtaaaaaaa gaagtaattc tgctgtagct tgggcatctg aaagggctgt gtgtgcgtgt
     8821 ttaagaggaa ttcctaattc tcgacacaaa atcggcaagc tatatttttc cagttcaggg
     8881 aaaaagacct gggccaattc gaccgtatca acacgagggt ttcttagctc atagccttca
     8941 aaaaataaat tttccgccaa gagattagca tcaaactgaa cattatgggc tacaaaaatc
     9001 ccatcctcca ccaagtcaaa tatttttctg gcaacttgcg aaaaatcagg tgcttgcgcc
     9061 agacgttggt ctgtcaatcc tgtcagttct ttgatatgag catccaaggg ttcatgtgga
     9121 ttgacatccg tcgtatagtg atcgacgatt tctccgtcct caatcacgac aattcccact
     9181 tggataattt tagccttact acctgtgcta gttgcctcta aatccaccac aacatagcga
     9241 ttaccaatcg ttttcattat aaaaaattat accaaaaaaa gggccatttg gcacctgcaa
     9301 acataggata attttcaaac tcaagaacac tacttttctt aaaaatccca tcgaatagag
     9361 cattctagcc tgctgatttt tttaaaatag tgaagaaata cgaaaaattg agagaagaaa
     9421 tgttttcatc ttccttctct caacgaatca tgtattttat ttaaccatgt caggatcgta
     9481 gtcataaaat cctgtatcaa ggaaacggtt tttagggtga agtttacgaa cttcttcatc
     9541 cagcaagaag gcttggtcat ggctaaagtt gccctcttga atcaagctac gcgcttggat
     9601 aaagagtttt gcaatctcaa caaagttctg accaggagtg tagagccctt ctagtttcca
     9661 gcgagtaaag ccatgctcca ccaattctgt taatttgatc atcaaatcaa ggtcattgtt
     9721 ggcaaagata tgggtcccat gattatcttc aaaaatggaa tagtggctct ctggatcact
     9781 tggctcagcc aagaagaggt cacgtttatg cgtcttttca tcatcgatat gtgtaaagtt
     9841 atagtagttt tgcaagagcg gacgtttaga atgatggatg acactagcac cgtaaaccaa
     9901 aacttcagca ggaatttcca aaatctctgg cattttgaaa agttcagctg atggaatttc
     9961 acgcgccaaa acagcctcag atgcaccagc cttttgtccc cagaagttaa tctgacgact
    10021 gctagttacc atggttgaag catcgtagat ggtcttaaat gaataaccat cgcggttgac
    10081 tacgtaaaag acgcctgcat ccccaatcgt aatatagtct gtcttgattt cttccaataa
    10141 gtctaagaaa ggcttgatac ggtccatcat atcttggtgc atgagagcat tgaccgcaac
    10201 gatcaattcc ttaccagcat catgaaccaa cttagcgatt tcacgtaatt ggtcataact
    10261 aaaggtcgtt ggcagacgaa ggccaaaatc tttctcaccg acatagatac ggtctacgcc
    10321 agcttcgagt agttgttcaa cttgttcaat actttcagca gttgctgtaa tgacaatctt
    10381 ttccataaga aaaattatac cacatttctc caaaatcagc catgctttga aaatgaaaag
    10441 ggactttatt ctttttgtaa cctttctgta ataattctct gccgaaaaaa tgataaaata
    10501 ggtatgtact gttaaggaga gaatcatgcc cgtaagaaaa ttacaatcct atgaggtaga
    10561 ctatcaagaa gaattaaacc agcagcttcc tcattaccaa gcttatacac ctgaagcgca
    10621 atctgatgcc aatctcaagg aaatcctatt ttttattaat atcgctgttt tttgtatctg
    10681 tattgctatc tttagtttta tctttttagc attaaaatta tcaactgctc ttgcctttgc
    10741 cgcagcaatc ggattcagct tacttgtttt aaaagttcaa cggtctatta tcaaacgaaa
    10801 acgtagaaga taaatccaaa atatcgcccc aattggagcg atatttttat tttttctttt
    10861 tagatggtgt ctgaatggca atcttcactt caaagattgt tcccttgggt ttattatctt
    10921 tgacagtaac agttcctttt agagcatcta caatttgctt ggctagggat aatcctaaac
    10981 caaaaccacc tttttgccgg gttctagcct tgtctactcg ataaaaacgg tcaaaaattt
    11041 tctttttatc ttctgtcgaa ataccgattc cattatcaga aacaagtaaa taaagattgc
    11101 gatcggtcgc cgagataaga aaatcaattt caccatcctc ctcagtatac ttgacggcat
    11161 tatcgaaaag aatggtcatc agttgtttca gaagaagctg atctgtgaca attgttcgat
    11221 ggatacgatt ttcaaaacgg aagacacgat tattttccga agcaatcatc tcatagtttg
    11281 tgaaagttgt attaaaaaag ctagttggaa cttctgcaag ctccggctta atcccatcat
    11341 ctctccgagc taagttcagc aagcttgtcg ttaaaaaacg catatttcgg acttcttcca
    11401 aactcgatgc aatgctttcg ctcacatcca taatggtagc ttctggctta cgaaaaaggg
    11461 tctctaagcg attttgcaaa actgcgagtg gagttcgtaa ctcatgactg gcattttcca
    11521 caaaagactg ttgcttctgc atactctcaa gcaggggcct aacactgacc ctagctagat
    11581 agagactggc aagtaaagac aaaatccaga aactagccat cacgaccaca atcaattgct
    11641 catgcttttg actagcctgc tccaactgac tggtattaat caagacagca gcatacttga
    11701 tattggttga aaccgaacta atattggtct ccatcaaaat cacacgatag atttcttcct
    11761 gcccatagct attaaaaacc tgaatctggt agatatgtcc tagttctttc ttttctaact
    11821 taatcttatc caagcccaaa aatcgatttc cagaaagaag ttgagtaaag tccttatcaa
    11881 agagaataac ttccgtattg gaactgacat taggttttat ttctacttta ctagcgtccg
    11941 ccctagcatt ttctaaatct ttaatctctt ctgttgccct atttatagcc agctgaataa
    12001 ctgcttgagg attttcactc agtccatgaa gcttatcgtc caccgaagta taaagactcg
    12061 aatgcatgac ttgtaaaata atcagagtca ttgtagaaaa aatcagggtg aagacaccga
    12121 agttgcggat aaaataacta aagtcatccg cataccatgt ttttttaagt ttactgaaca
    12181 tcttttaaaa gatacccaac actacgcaag gtttgcaaat tctctgcaaa agtggttccc
    12241 tttaatttct tacggacttt tgaaacatag acttcgacaa ccgaaatcgt tgtatcacta
    12301 tcaaatcccc atagacggtc aaaaatctgc gtcttaggca aaatcacatt ttgattttga
    12361 aggaaataaa ctagtaaatc gaactctttc cccagcaatt cgacaggagt atcttcaact
    12421 ttaacggtat tggttgataa attaaccacg atattcccat aagtcaaggt gttttcatta
    12481 aacttccctg aacgtttgag aagggcctga atccgcattt taagttcttc taggtagaaa
    12541 ggtttggtca gataatcatc cgctcccagt tcaaatccat gtcccttgtc atccaaactt
    12601 tccttggcag tcataatcag aactggtgtc gtaattccct tttcacgcaa ttcttttaag
    12661 acttggaaac catttttttc tggcaacatc aaatccagca aaatcaagtc atagacacca
    12721 ctctcagctt cgtagagacc ttcttctcca tcaaatacct gcataacatc cgcaaaatcg
    12781 tctaaaaagt caaatactga atttgacaga cctaggtcat cctcaaccaa taagattttt
    12841 atcatgagaa actcctcctt attaaaacta ttataccaaa tttgccttaa aaaaaactca
    12901 actctctgca ttttacatga gatagctgag ttttcttttt attttaggct tatttatgca
    12961 tttccgtatt gaagaacaac tgcttcgact gcagcttttt cacggctaat caagtcaaca
    13021 cgtgctgcaa tttccttgat tcccataccg atgttacggc taagagcaag gtcagaaagt
    13081 tgcggctcaa agaactcctt gtattccgcc aagcgttgct gagtcttaaa tacatgagca
    13141 ggaaggataa caaagctatc aaagctcata tctcctccaa gggctgcctt aatccaagcc
    13201 cagttttcac gcgcccaaga ccaagctgtt ttctgagttg cttgatgagc taggaattga
    13261 taataccaag cagacaagtc ctgtggtttg accacaaatt tgtccttcca agaagtaatc
    13321 aagttttgga tattatccgc atctgtactg tatgcaagag ctgctgccaa ctggcgttta
    13381 aagacagcat ctgttgcgtg agtataagta tcaagataaa gtgctaacaa gtctttagtc
    13441 tcatgatgtt tcatctcatt aatcagaact tgtgaacgaa tagctgctgg gagtcctgca
    13501 agattctcct tgtgtgttgc gaagatttgg ctagcgactt gactagcttc tgcatcattt
    13561 gagcgaatca tcatcgaaac agccagctga cgaaccaatt catcctcatc tgattctccg
    13621 tctttagctt caaaaccaag acggtcatag ttatgacgag ccaatttagc aaccagtcct
    13681 ttgaaggctg tttcagcatc cgttccttca tcaataaagc gctcaagggc tgaaatcact
    13741 tgagaaacag ctgaaaccac cagataagac tcttccttag caagtttatc aagaactgga
    13801 agcaagtctg cataagaaat gtgccctgcc tcagccaaca aacgacgttc ttgaacaatt
    13861 tgcagtttgc ttgtgttatc aagtgtctct agctcagcaa gaacagcttc taacaagtct
    13921 ccttgatagt cggtaatata gtgggcagta ttttcagtgt tgagacgaag agctccttca
    13981 ttttcagcaa gaagagctgc gtagccaggg atttcgatac tttcagtttc gagtgtatca
    14041 ggcaagcctt tccagttgct attgaggggc accacccaga gacggttctt gtcttcgttc
    14101 tcaccgatga agaattgttt ttgtgaaatc ttcaagacat cattttcaac tttgacagta
    14161 agaactgggt aaccaggctg ttccaaccaa gaatccatga aggctgcgac atcacgtcct
    14221 gacgcttgac caagggcatc ccaaaggtca ctaccaatgg tgttgctgta ttggtgtttt
    14281 tcaaagtagg cgtgcaaacc tttagcaaaa tcagcatctc ctagccaacg gcgaagcatg
    14341 tgcatgagac ggcttccttt ggcatagacg atagcgccgt caaagagtgt attgatttca
    14401 tctggatgtt taacttcgac gtggacagac tgaacgccat cagtagcgtc acgttcaaga
    14461 gcaagaggta ctccacctgt ttggaaatct tcaaagatat tccagcttgg ttcgatggta
    14521 tccacacaga cgtattccat catattagcg aaactttcat tgagccaaag gtcatcccac
    14581 catttcatag tcacgaggtt cccaaaccat tggtgagcca attcatgggc cacaacaagg
    14641 gcaacttgtt gacggctagc aaatgtagag ttctcatcga caaccaagta aacttcacgg
    14701 taggtcacaa gaccccagtt ttccatagca ccagctgaga agtcaggaag ggcgatgtgg
    14761 agagattgag gaattgggta cttaactcca tagtaatctt cgtaaaactc gatagagcga
    14821 acagcgatat ccagtgagaa atcaagattt gaaagtggat gtgctttggt tgagtagaca
    14881 cctaccaggg taccattttt agttttagcg gtcacccctt gcaaatcacc agcaacaaag
    14941 gccaacaagt aagaagacat gcgaggtgtt gtctcaaact tccagatacc tgtttcctta
    15001 cggttttcaa catcgatttc tggcatgttt gacaaggcca attcaccttc tgcttggtca
    15061 aagcgaagag agaggtcaaa agttgctttg gcttcaggct catccacaca cgggaaagct
    15121 tcacgcgcaa aatggctctc gaactgagta gacaagacct ccttcttgac tccatcaact
    15181 gtataataag aagggtaaat ccctgtcatg ttgtctgtaa ttttaccaga aaaggcaaga
    15241 accaattcaa cttgaccagc ctcagccaat tcgatatgaa gggcttcatt gtcatggtca
    15301 actgtaaatg gacgagcttg acctgcaact tctacagagg tgatttccaa gtctttttgg
    15361 tggagggaga tgcggtcact ctgtgcttga ccagtgatgg tcactttccc agaaaaagtc
    15421 ttggtctcac gactcaaatc taaaaataaa tcataatgtt caggaacaaa ttgcttaata
    15481 aaatgttcaa ctgcttgcat agttttctcc tattctaagt ttaagagctg ctgctcttct
    15541 tcaaacaaac ttattatatc atattttgct tgagaaaaaa ggattggaca gcgatttcca
    15601 aaactttctt ccttctaata gtctacagtg ggtagacctt gcgaaattct tctaaaacaa
    15661 ccttgctttc aggtgtaaaa gtcagcccta cttcacccaa acagtctgtg aaaaagtcct
    15721 catgaacctg gcgccaatag gcaagtgatt tgtctccctc accttcctta aaggcatgtt
    15781 gcgcagaaac ttgattgaag agttcaacag aaacctttgt aatttcgaca atgcagacag
    15841 cctgattttg actatctaaa atgacatcga aggtccctac ttggggaagt ggttcgtctt
    15901 ctagtacata gaggtcatag gctgatgctg ttgctgtctt ttctccttta aacaccaaat
    15961 ccgctaaaag gtctggttca actccaaaag cccaagcatc gatttcatct ccgatcaaag
    16021 gattgatttg cttgtattta ttccacattt cttgcggtgt catgggtact cctttgtaat
    16081 tttttacttt cttcttttat gtgtttaaga tgatctggat ggtcaatctc taaatcaaaa
    16141 atctctggaa tagaactgta gtggataatg cacttgatac ccaactgatt cattttttgt
    16201 atgaaagaag tattcagata gcctgctaca gcaaaattaa tcttgttctt tcttgcttta
    16261 tcctgcatat ctcttagcat atctaacatt attggacttt ccatatcatg ccattgactg
    16321 tttctcatag tcgcaaaaac aaaggaagtc aaatcattca ttccaactac aatctttgaa
    16381 atgcccgttt ccagtatcct atccaagtca aaatacgctg acggtaattc aatcatcgtt
    16441 ccgactttcc cagtaaagcc atactgacgc aatactgtaa tagcttgttt taattggtcg
    16501 gcatcattga caaaaggaaa gataagagat agattgggat tggtttgata aacttctgta
    16561 acgacatgtg cttcagcctg aaattcatcc aaacacgcca gtaaacgcct ggttcctcta
    16621 tagccaaaca agggatgccc ttcgtcaaaa aactctctag tccccactaa acaattggct
    16681 tctgtattcg ttaattcaga aaaacgatac caaacttcct tacctaagta aaaggagcaa
    16741 atagtatcaa gataatcttt cacaaattcc tgacaacttg ctaatatgat gttttgatta
    16801 agctctctca acaaatattc cccacgaatc atgccgacgt ggtgaaatag ttgaggataa
    16861 attttttcaa gaattttttc gccactaagg gcaagttgat ttctcatcat tcaccttcca
    16921 attcatgtaa gaagtcttgt ccagttctgg aaatcctaat aattcagact taaccttcaa
    16981 gactaatggc gatgcatttt cttctgtaat ctcttgaata tccatccaaa tatatccaag
    17041 tgaatcattc gcaccatcag acacagcttc cgaagtcgta acttgaggtg cactctcatt
    17101 catttcaaca tcatacaagg ccatgacatg gtgaaccata aaattggtta actcttctct
    17161 gacgaaaaca tcgtagattc gaggattaga gtagcttata acagtaaatc ccgtctcttc
    17221 cataacttct ctagtcagcg tttccgtcag tccttcacca agttgctgac tgcctccagg
    17281 tagatcatac cgatgttgat aagggcctct cgctttttca atgcagagta acttcccatt
    17341 ttctaagcaa acagcgtaga ctccaaagtg ttttttgatt tccatccaac tcctcctact
    17401 tcaaagacca gccaccatct attgtcaaga tttgtccttg catggcagat gcctttccac
    17461 tggccaaaaa gagactgact tctgccactt cctctggttc aatccagcgc ttgattggtg
    17521 tttcactagc cacccagtca gctaagccac ctggctcaaa atccgcagcg gtcatagccg
    17581 tcttgactgc tcctggagca atcccaaaga cctgaatccc agcttcagca tagtctagag
    17641 ccaactgctt ggtgaagcca gccaaggcat gcttggatga agtataggcg tgaccacctc
    17701 cacctgctag gctagaagca atggaacaca tattgatgat gattcccttt ttattttcca
    17761 gcatttgtgt caaataatac cgagtcaact caacaggagt catgtagtta atttcaaaaa
    17821 tctcttgaat ttcctgcgca gtctgttcca acagtggttt gtaatcatcc aaaactccag
    17881 cagtattaca caaaacatcc acctgagggc accagccaaa aataggttcc aagtccaagg
    17941 tcaaatctct ctgtaaaaaa tggaaatcac cctctaagag tggattttca ccttggtcaa
    18001 ctccataaac ttgaaagccc ttctctaaaa agagtcgagc ctgagccaat ccgatacctg
    18061 aactcactcc tgtaataagt acacgtttag tcatgcactt ctacccaatc cgttgccaaa
    18121 acatcacaag ctgtcgggct ccacatggaa aaaccttctc cttcgccaga aacgttgatt
    18181 aggaaataag gtgtcacttc aagtgcaagc ccgttttgtt caatggtgtc aaaaagttgg
    18241 acatagtttt ccgcacctcc ccaaccagtt cgtacatatt ttttcttagc ctttaagcca
    18301 ggtagaattt cttcaaatgt catgtttttc tcctttaatg tcaataattc tccccttcat
    18361 tataacaaaa aaaccgcttt aaaacggctt tttgactgtg atttatttac atcttcttct
    18421 acttacggca aattattccc tgcagcaaga taaatttcat accattcttt tcttgttaag
    18481 ctaaagtttg ccgctcggct aacttctctc aagtgcttag gatttgttgt acctacgact
    18541 gcctgcattt ttgctggata acgcaatatc caagaaatgg caatagttga agaggttact
    18601 ccatatttaa tagctaaacg atcaagtact tgatttaaag cttgaaattt ctcatttcca
    18661 acaaagttcc ctttaaaata cccgaattgc aagacagacc atgcttgaat gaccacatcg
    18721 tgtaatttgc aatattcaaa aatgctgcca tctcgcatag ctgcttgact atcttccata
    18781 ttaacatgaa aagctgattc aaatcctgga gtaaaagccg cactcaattg tagctgatta
    18841 acagctaacg gctgcttgac atctttttta agcaactcca tcatcatagg attttgatta
    18901 gaaactccaa aatctcgaac cttaccttgt ttataaagga gatcaaaggc ttctgctact
    18961 tggtcagatt ccatcaaagc atctggtcga tgaaggagca agctatctag atgatcaatc
    19021 ttcaatcttt gcaaaatacc gtctactgat tttataatat agtccttaga aaaatcaaaa
    19081 taggtaaatt cttcaatgcg aatgccacat ttggactgaa tccacatctt ttctcttaaa
    19141 tctggacgat tttttaggac aagacctaac agttcttcac aacgaccacg accataaata
    19201 tcagccaagt cgaaggcatt gattccaaca gaaagtgctg tttctacaag ctcttcaact
    19261 tcttttacag acttatcttt tattctcatc attccgagaa caatttctga taattctttg
    19321 tcatcttgac caagagttat gtatctcatc aaatttttct cctttaattt ctaacattct
    19381 tcccttcatt ataacaaaaa accgctttgc aacggctttt tgactatact tcactccatt
    19441 ttatcttctt aaacccacgg aacaagagaa aaatgccaat aaagaggaca gctaaaggaa
    19501 taacttttgt aaggaaaaca tttgaaattc ccatccactc ataataacgg agcagagaac
    19561 ccaccacaag atgggcaata atcatactga caaatggacg aaagaccgct tctttccaat
    19621 tccaaatacc gataactagc gaaatcgtaa agacagacaa actatcccag ggagccggaa
    19681 tataaaaggc tccttcttgt atgaagcttg ccattcctac atatcctaaa acaactagaa
    19741 gaactatagt cccaacaaca atgtaagtgc caattttcat tttaggagaa tcttggacta
    19801 aacttcttcg taaaattgtg gccacaagtc caaatccaat cagaaaaata agaagttgcc
    19861 ctaaaaatgt gagcaaattg actgttaaga gaggaccttt agaaaaatca cttagtagtt
    19921 gataataatg taataccgcc aggacaagaa ttggcgtcaa aagggactct ttgatagaac
    19981 tgcgaggtgc tcccttgaga atctctttca ttattttttt aggattctta cctagataat
    20041 cctctgcact catgccatct cgttctgctt ctgagaaatc tagcatcatc aaatagatct
    20101 gctctctgag atagtcttca tcatagagaa atccagcaag attaaaactt tcccacaact
    20161 cctcaaaata cttttgattc tcctcagaaa actcatgtag caaagcgctt gtttcttcgt
    20221 aatacttcat tttcttcatg gtttaacccc cattcttaat cccttctact ttttgactca
    20281 aatcgtccca ttgttgccaa aagactgaga cacgctcttc tccttctttc attaatgaaa
    20341 aatacttccg atctggacca tctggcgacg ggcgcatgtc gcctcttatc cattgatttt
    20401 tttctaactt ttgcaacaaa ggataaatag ttcctggaac gatagtatca aatccagcct
    20461 ctcgcaaagt ctgaaccaac tcataaccat accgctcttt ttgaccaatc atatccaaga
    20521 cacaaccttc aagaacacct tttaatagct gagtttcttt catcacttct cccttctaat
    20581 ctattttgta atacctacta gtaacttcac ctatagtata ttacttctac actagtttgt
    20641 aaagcataat agttaatact cttcgaaaat ctcttcaaac cacgtcagcg tcgccctacc
    20701 gtatgtatgg ttactgactt cgtcagtttc atctacaacc tcaaaacagt gttttgagct
    20761 gacttcgtca gtttcatcta caacctcaaa aacatgtttt gagctgactt cgtcagttct
    20821 atctacaacc tcaaagcagt gttttgagca acctgcggct agcttcctag tttgctcttt
    20881 gattttcatt gagtataaat aaaaaaacag aactagcctg aactagtcct gtctactttt
    20941 acccaatcac acttccattt ggtacagctg gatcaactgt gagaagggtt aatttgccat
    21001 catgttcagc tgagagaatc ataccctggc tgacatattt tttcatcatt ttacgtggtt
    21061 tgaggttagc aacgatttga actttcttgc cgaccaattc ttgttcattt ggatagtatt
    21121 ttgcaattcc tgaaagaatc tgacgatctt ctccatcacc agcatccaag cggaattgaa
    21181 gcaacttatc tgaaccttct actttagaca cttctttgac ttctgcgaca cggatttcaa
    21241 ccttgtcaaa gtcttcaaac ttgatttcat ccttgtttag tttgagctca acttcgtccg
    21301 gattccattc tttttcgact gctggtttat tgccttccat ttgttccttg atataggcga
    21361 tttcttcttc catatttaga cgtggaaaga taggtgttcc tttggcaact acagtcacat
    21421 ctgctgggaa gtcagccaaa ctcaagtttt caagactaga aacttcttcc aaaccaagtt
    21481 gagtcaaaac tgcacgacta gtttccatca taaatggttc aatcaagtga gcaactacac
    21541 gaatgctggc tgccaagtgg ctcatgacac ttgccaattg gtcacgaaga gcttcatcct
    21601 tggccaagac ccatggtgcg gtctcatcga tgtatttatt ggtacgagag atcagagtcc
    21661 agactgcttc aagcgcacgt ggatagtcaa ctgcttccat gtgtgtatgg aagtctgcga
    21721 ttgattgttc tgcaacctca gcaagaacat gatcaaattc agtcacacct tctacatagg
    21781 cagggatttg tccatcaaag tacttattaa tcatggaaac cgtacggtta aggaggttcc
    21841 caaggtcatt agccaattca tagttgatac ggccgacata gtcttcagga gtaaaggttc
    21901 cgtctgaacc aactggaagg ttacgcatga ggtagtaacg aagtggatct agtccataac
    21961 gctctaccaa catttcaggg taaacgacat tcccttttga cttagacatt tttccgtctt
    22021 tcatgacaaa ccaaccatgg gcaatcaaac gatcaggtaa tttaacatcc aacatcataa
    22081 gaaggattgg ccagtagata gagtggaagc gaaggatatc ttttcctacc atatggaaga
    22141 ctgttccatt ccagaacttg tcaaagttac catgttcgtc ttgagcgtag ccaagagctg
    22201 tcgcatagtt aagaagggca tcaatccaaa cgtagacaac gtgttttgga tttgatggga
    22261 caggcactcc ccatgtaaag gttgtacgag ataccgccaa atcttccaag cctggctcga
    22321 tgaagttgcg tagcatttca ttaaggcgac catctggcgt gataaattca ggatgagctt
    22381 tgaaaaattc gaccaaacgg tcttggtatt tgctaaggcg aaggaagtat gattcttcag
    22441 aaacccattc aacctcatga cctgatggag caataccacc agtcacattt ccagcttcat
    22501 cacggaaaac ttctgccagc tggctttctg taaagaattc ttcgtctgat actgaatacc
    22561 aaccagagta ttcacccaag tagatatcat cttgagcaag taagcgttca aagacttgtg
    22621 cgacaacttt ttcatggtag tcatcagttg tacggataaa tttatcgtat gagatatcta
    22681 gtaattgcca gagttcttta actccaaccg ccattccatc aacataggct tgaggtgtaa
    22741 taccagcttc ttccgctttc tgctggattt tctgaccatg ttcatcaaga cctgtcagat
    22801 aaaatacatc gtagcccatc aggcgtttgt aacgtgctag gacatcacat gcgatagttg
    22861 tgtaggcaga accgatatga agtttcccag atggatagta aatcggcgtt gtaatataaa
    22921 aatttttttc agacataatt tttcctttcc aggcaaatga aacctgtttt tctaacactt
    22981 cattatatca catttttaat gaatttcgat agggaaatcc atacaaaaac aagatagacg
    23041 agtgtccatc ttgttgatct cattcataac gaagggcttc aattggatca agtttcgatg
    23101 ccttgttggc tggcaagact ccaaaaatca taccaacact agccgaaact gcaagactaa
    23161 atagggcaac tgggattgat actccaactt ctataccttc tattaaacct tgcagtaaca
    23221 aacctgctaa ggcagttaaa ccacttgcaa ttgtcaagcc aattaagcca cctaacaagg
    23281 tcaaaatcat ggattcaatc aaaaactgaa ttaaaatatt ggcacgtgtt gcacccaaag
    23341 ccttacgaag accaatctca cgagtgcgct ctgtcaccga aaccagcatg atgttcatga
    23401 caccagttcc tccaacaaag agagaaatcc ctgcgatgga actaataatc gtcgtcataa
    23461 aactaaacga ttgttgaatt tctgcaaata caacggactc atctgccacc tggtattctc
    23521 cctgttgtaa gcctgcaagc tctgtcattt ttcgtgccag ttctggaccc agagttgggg
    23581 ttaaactggt atcattcact cgaaagacaa tattagctat ttcatctaca ttaaaattcg
    23641 cagcaaggga gatattggta gtaataggca agccaccaaa cccatatatt tttgatcttt
    23701 tagcctccgg actagtataa accccaatga cccggtaact aaatccattg acttctacaa
    23761 ccttgttaat agcctcttga ggagattcaa ataaactaat ggacaattcc tcatctagca
    23821 aaatgacact tgcaaactct ttgaaatctt gctctctcag actacgacct gcaataattt
    23881 cattcttaac agcgtccatg taagttctgt ttccacctgt caaattagca ttctcaacct
    23941 ttttatcttg ataggtcaag atggcattcg ttgaattggt tacatagtaa ctatccactc
    24001 ccttcagttt agctgcctct tgaacccagg attcttgcgg ttttggcggt tcaacaggaa
    24061 cttcctcttc ctttccagaa accgtaaaag ctgattgttt ctgagtaaaa gacccatctt
    24121 tacttttttt aggagagaaa aagacgctaa tatttttctg aaatttagtc atatctttat
    24181 tgacttgacg agatagggaa tcacccaaag ccataatcac aacaactgat gaaacaccga
    24241 taataatccc aatcatagta agcaaagaac gcatcttgtg agccatgata gatgaaaagg
    24301 caaatttcag attctgcatc ttagttttcc tcctttccta actgagcact gtcagacgaa
    24361 atgaccccat cccgaatgac aatctgacgt ttggcatagg cagcaatctc aggctcatgc
    24421 gttaccatga taatggtttt tccttcttta ttcaaatcaa ccaataattg cataatttgg
    24481 ttacctgttt tggtatccaa ggctcctgtc ggttcatccg ctaggataat agaaggattg
    24541 tttaccaagg cacgcgcaat ggctacacgt tgcttttgac caccagataa ttctgaaggt
    24601 aaatggtgac tacgttctgt caattcaacc ttgtctaaat attcctcagc caacttgcga
    24661 cgttttgaag acgaaactcc tgcgtaaatc aagggcaatt ctacattttg cagagcattg
    24721 agcttcgata gaagaaagaa ctgctgaaag acaaaaccga tttgttggtt acggacctta
    24781 gccagttgtt tttcaccaag cccagccact tcttgacctt caagataata ttctccactg
    24841 gttggtgtat ccaacatgcc aatcgtattc atcagagtgg acttaccaga cccagatggt
    24901 cccatgatgg ctacaaattc accctcattc acttctagat tgatattttt gagaacctgc
    24961 agttcttggt caccattacg gtagcttctg aagatatttt ttagactaat tagttgcttc
    25021 atcagccttc acctcttttc cttcttccaa ggaagatgtt ggattactga tgaccttagc
    25081 accatttgtc aaaccagaag tgatttcttg attttctgcg tcagcatttc ccaatgaaac
    25141 ctcaactttt ttagcctttt gttgttcatc cacaatccag acataatttt tactatcatc
    25201 cattactaga ctgctaacag gaacaagaat agccttagtt ttgcttttaa cctcaatgtt
    25261 gacagaaaaa ccttgtttca aatcaccaac ctcgcctgtc acatcaatag tataagggta
    25321 tttagaacct gtattattcc cggctgctgg actagctgct tcaccattgt ttttaggata
    25381 gtcagaaata tagcttaatt tcccagtcca ttttttatca ggatacactt tagaagtaaa
    25441 gcttacttct tgacctacag aaaggttggc tagattgtac tcagacaatt ctcccttgac
    25501 ttgtaaattt tcattgctga caatatgaac cataacttga ctcgcccctg ttggagattt
    25561 agaaacattg ctattgactt cgaccacagt tccctctagg gtactgagaa cagttgttgc
    25621 atccaattga ctttgagcct tgcttaattg cgccgcagca tctgcacgcg catcacgggc
    25681 atcacccaat tgagcgtcaa tagaagcaac agaatttcca gccactggag ttgggctttg
    25741 caccgttgca tcttctcctc ctactggcgc tggtaactgt ggagccggag ctgaagcggc
    25801 ttcatttcgt gcttgattga gttcattgat atgacgatct gccctagcta ctgctcgact
    25861 agctgaatca taggccgcct gcgcttctga actactgtac ttgactaaag cctgcccttc
    25921 gctgacctta tcgcccacag aaacaaggat ttcatctaaa tcacccttac tagcatcaaa
    25981 ataaacatat tgttcatttt ttgctgttac tgtccctgac aataaaacag aggaggccac
    26041 gcttccttcc ttggcaacaa caagatgagt aggctcatct tttagagcag tctgagaagg
    26101 ttgtctaaag agtaaaatcc ccccagcacc caatacaact acactcgcag caccgattgc
    26161 tgcatacagt tgccactttt tagctttacc attctttttc ttcataatga aactcctttt
    26221 cttttttaca atactttgct attataccaa atttccctcc agcaaacaat acagttcagg
    26281 attaaacaat cgttcggaat tttgcttttc tattgtacta gatatataat acactatctt
    26341 gacttatttg gcaagctttt ttgcaatttt ttgtgcgtag cagatttttg caatcaaatc
    26401 aaaaaaagaa taaaatataa ctatcaaaaa agacgctcta ctatttaaaa gattacaaag
    26461 gagttttcaa tgagagaata tgatatcatt gctatcggtg gaggtagcgg aggaatcgct
    26521 accatgaacc gtgctggtga acatggagcc aaagcagccg ttattgagga aaagaaatta
    26581 ggtggaacct gtgtcaacgt cggttgtgtt cctaaaaaaa tcatgtggta cggggcacaa
    26641 atcgctgaga ctttccatca atttggagaa gactacggct ttaagactac tgatcttaac
    26701 tttgactttg caaccctacg tcgcaatcgt gaatcctaca ttgatcgcgc tcgttcttct
    26761 tatgatggca gttttaaacg caacggtgta gacttgattg aaggtcatgc tgaatttgta
    26821 gattctcata ctgtaagcgt aaatggtgaa ctgattcgtg ctaaacatat cgtgattgct
    26881 acaggtgccc atccaagtat tcctaatatt cctggtgctg agctaggtgg ctcttctgat
    26941 gatgtatttg cctgggaaga acttccagag tcagttgcca ttctaggcgc tggttatatc
    27001 gccgttgaat tagctggcgt actccacact tttggtgtca agacagatct ctttgttcgc
    27061 cgcgatcgtc ctttacgtgg ttttgattcc tacatcgttg aaggtttggt caaggaaatg
    27121 gaaagaacaa acttaccact tcacactcac aaagtccctg tcaagttaga aaaaactact
    27181 gacggcatta ccattcattt cgaagatggt actagtcaca cagctagcca agttatctgg
    27241 gctacaggtc gccgtccaaa cgttaagggc ttgcaacttg aaaaagctgg agtgactctg
    27301 aacgaacgtg gctttatcca agtggatgaa taccaaaata ctgttgttga gggaatctat
    27361 gctctaggtg atgtaacggg cgagaaagaa ctgactccag ttgcaatcaa ggccggacgt
    27421 accctatctg aacgtctctt taacggaaaa actactgcaa aaatggatta ctcaactatt
    27481 ccaactgttg tcttttcaca ccctgctatc ggaactgttg gtttgacaga agagcaagct
    27541 attaaagaat acggtcaaga ccaaatcaag gtttataaat caagctttgc atctatgtac
    27601 tctgcttgca ctcgcaaccg tcaagaatcc cgtttcaaac tcataacagc tggttcagaa
    27661 gaaaaagttg tcggacttca tggaattggc tacggcgttg atgaaatgat tcagggattt
    27721 gccgttgcta tcaaaatggg agcaaccaag gctgactttg atgcaactgt ggcaattcac
    27781 ccaactgcat ctgaagaatt tgtaaccatg cgttaatcga aacaaaagaa gctgatataa
    27841 atatgtctgc ttctttttta atgattttcg aatcaacaaa aaaattatcc aacttgacta
    27901 gtcacgaaaa tcggctgtta cagtttttgt taccttgttt ttaaaaaatg gttgacatcg
    27961 actcctatat gagtataata gttactatac attagaaaag aggttaacta ttttgaaaaa
    28021 agctcacgtt tatgctatcc ctgctattgg ggctgctctc attgctgttt tggcacaaat
    28081 cagtcttcca attggacctg ttcccttcac tctgcaaaac tttgcaatcg gcttgattgc
    28141 tactgtcttt agaccgagag aggctgtact ttctgctgga ctctatcttc ttctaggtgc
    28201 tatcggtctt cctgtctttg caggaggtgg agctggtttt caggctttag ttggccctac
    28261 tgcaggctat ctttggtttt atctcgttta ctctggactt acttcctctc taaccaacag
    28321 caagagtggt gttgttaaga tttttcttgc aaacctcttg ggtgatgccc ttgtctttgt
    28381 cggcgggatt ctcagcttgc atttcctagc tggaatggca tttgaaaaag ctcttgttgt
    28441 gggggttctt ccctttatca ttccagacct tggcaaactt ctggctatta gttttattag
    28501 ccgtccccta cttcaacgcc ttaaaaatca ggcttacttt actaactaaa aaaggatacc
    28561 gagttatcat gactcaatat cctttttttt attttgaaaa cttatactca atgaaaatca
    28621 aagagcaaac taggaagcta gccgcaggct gctcaaaaca ctgttttgag gttgtggatg
    28681 aaactgacga agtcagtaac catacatacg gcaaggcaaa gctgatgcgg tttgaagaga
    28741 ttttcgaaga gtattagttg cctttaaagg catccaccat cgtttgaaat tcttcatttg
    28801 agagagtaat ccctttgccc attttagtat ggtttggact ccaagcacga atatcaaact
    28861 ttgcaggggc accattaaag ctcacacggt taatttcctt ggtccaacct ttttcgtttt
    28921 cagaaagagt caacaagtgc tcttcgattt caaatgtaaa ttctgccatt ttcttctcct
    28981 tttttagttt cattagttta ttcgtaaaat cttgtagatt ttaggaaaat tttatataat
    29041 attgatataa aataagggag gccaatatga gacataaatt ccagcaagtt ctagataaaa
    29101 tacatgattt tttaaatgga catgaccaac ctgaccagac tgaaaccaac tcccttacag
    29161 ccactattga agaggctatc cagaaacaaa ccgctgttca ccttatcttg tctgagacaa
    29221 gttttacagg tgatatcatc aaatatgatc agcaaggcca gcaaattatc gtgaaaaatt
    29281 ttgccaaaaa tgtgagccgg attatccgta taagcgatat tcaacgcctg cgatttgtcc
    29341 cctcaactgt ccaaacagcc caaaaaaata gatttaagaa agagtgagat gtagttgctt
    29401 catcccactc ttttttctta gcgaatttgt tcaaaatgta aatgaactgc aatatgatct
    29461 ccataaccac ttctttccaa gtcacgttgt aaacgatagg aaatgtagtg ttctgcaata
    29521 gtaatgtaac ctgcgcccaa taaacgatgt tcaaccatag attgaatcat actgatagtc
    29581 gcacgttcca ccttggcttc ttgtaaatcc aaaactacct tcttagtgac ttgagcaaga
    29641 ttttgacgca aatcatctgt caaaacataa acagtttggg ctgccttcaa gatggcttgg
    29701 taaatcttat ctggattaaa ttcagcaatt tcgccattac gtttgattac ttgcataggt
    29761 ttctccttta ttctttgttt tctttgattt ctgccagcat tttttcttct tctactgtca
    29821 gttgataatg ttcaagtaaa tccggtctgc gctcgtaggt tttctttaaa ctctcgtaca
    29881 atcgccactg acgaatcttt tcatggtggc cactcatcaa tacatctggc acgaccatgc
    29941 ctcgataatc atagggacgt gtgtactgag gatattctaa aagacctgaa gaaaaactat
    30001 catcttggtg gctagactcc ttgccaatca cttctggaat caggcgaact gtagcatcaa
    30061 tcatggtcat agctgccaat tctccaccag tgaggacata gtcgcctagg gaaatctcat
    30121 ctgttaccaa ggtcttaatg cgctcatcat aaccctcata gtgcccacag ataaagatta
    30181 gctcttcctc ttgagccaaa tcttcagcat aagcctgatc aaactgcttt ccagcaggat
    30241 cgaggagaat aacgcgcgga tttttctttt caatagcatc aaaggaatcg aaaataggtt
    30301 gtgctctgag caacatgccc tgaccgcctc cgtagggctc atcatctaca tgacgggcct
    30361 tttcagcatt ttctcgaaaa ttatgatact ggatatccaa gagccctttt tctcgagcct
    30421 ttccaacgat tgagtgctcc agtggagaaa acatctctgg aaagagggtt aaaatatcaa
    30481 tcttcatcgt ctaacccttc taagatttcc acatcgaccc gtttatttgg aatatcaaca
    30541 ttgagaacca ctggtgggat ataaggtaaa agcaaatcac gtttgccttt tcgtttgacc
    30601 acccagacat cattagcacc tggttgcagg atttccttga tggttccaac caagctatca
    30661 ccctcataga cttccaaacc gataatctcg tgatagtaaa attcaccatc gtctaggtca
    30721 ttcaaatctt cctcagcgac cttgagactg tatcccttgt acttttcgat agtattgata
    30781 tggtacatat ctttgaattt aataatgtca aagttcttct gtttacggtg gctagcgatg
    30841 gtcactgttt ggacaaactg atctttttca tcaaacaaag ccagctcagc tcctttttta
    30901 aaccgttctt ctgcaaaatc cgtcacagac aagactcgca tctcaccctg taatccctgc
    30961 gtattaacga ttttcccaac attaaagtag ttcatcttgt ctcctgtaat ctcctttttt
    31021 ccatcttatt ctgacaattc tcgaataata gccgcaattt tttccgattc tgaccattgt
    31081 aaataatggt gattccctcc taaaatgagt ttagtattgg aagtccaata ttctgattct
    31141 ctgtactctt tttctctata aggctgacaa aaaacaaata caggaatatg agcttctata
    31201 gatacatcct caaaatcttc ctcagtaatc tctccagata tctgaaattc tggatcttga
    31261 ttttccaact ctaagccttt ttcttgcatt aattcccaga tttttttatt cgtttcagga
    31321 ctaaatgttg cttgagttaa attcttcaaa taaagttcag gtccatactc gtcaatcagc
    31381 ctcatctgct cttccatttc tggataagga ttttctgaaa aatcagcaaa catgactttt
    31441 ttagttgtcg gttcaattgc tactaaagtc tgacacttaa ttggtttctc gagtaatttg
    31501 caagctaaaa ttccactcca actatgtgca caaagtatat attcagaaat ccctaattct
    31561 tcaagtactt cataaaccac atctgcaaga ttatctagat tttttccagc ttggtcatga
    31621 atcggactcc tacctgtgtt cggaaaatca attgtcaaat aaccaattgt aggaggaggt
    31681 ttttcaagta taagtgaaaa attttcataa cttggtagca aacctgctcc gtttagacaa
    31741 actagcactt tcttttgctt ttgataagta acagagaggc taccaatttc tgtagatact
    31801 tcaaacctct tcataaagaa atccactcat tctatataat gaattattaa aaatccttat
    31861 cctttatttt atcacgttcc aaggattttc tcaagttgga ggaaggggac aacatctcta
    31921 ctttcccttc aagaatcctt ccaaatcatg tttatgttgg taattaacga ctgcggtttt
    31981 gtctttctca aagacagtct tggtaaggtc aatatgcttg atagcagcaa tagcgacggt
    32041 gtagtaaatg atatcagcca gttctctggc aagttcctcg ttcgaatcct atcccttctt
    32101 ttcgaccaga gcgcctattc aaaacctcgg ctacttctcc gacttcctcc actaacttca
    32161 taaagagacc ttcatcagtc cgagactgct gttaatgttc gagtaagtag tcttggaatt
    32221 gcctaaacgt tcaatctttt atagtatatt gaaactagaa tagtacacct ttacttctaa
    32281 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgttctt gtttcatttt
    32341 actatatctt ctattccaca caaaaaagcg agacatccgt cccgcccttc ttatttttcg
    32401 tcaataacga ttcttacttt tttgtattca gttgggacag agtagacaat cgttcttatc
    32461 gcagaaatag tgcgaccctt acgaccgatt acacgaccca catcgctttg atcaagattc
    32521 aaatgatatt ccaaaaattc tggtgtatcc tcaatcttga tagttaaggc atctggttgt
    32581 gaaattaagg gtttcacaat cgcaataatg agattttcaa tcgtatccat ctgtcaacct
    32641 actttaaact tattttgaaa atttagaatc gtggaatttt ttcaatacgc cttcttttga
    32701 aaggatgtta cgtactgtgt ctgaaggttg agctccatta gccaaccatg caagaacgcg
    32761 gtcttctttc aaagttactt ggttttcagc aacaagtggg ttgtaagttc caactgtttc
    32821 gatgaaacgt ccgtcacgtg gtgaacgtga atctgctacg ttgatacggt agaaaggttt
    32881 tttcttagaa cccatacgag tcaaacggat tttaactgcc atttttaaag tctcatttct
    32941 ttaatttttt atttcggtga aatagctgag ctatttagca catgttctat tatagcagat
    33001 ttctggcatg tgtcaagaaa aaaacttgac agactataaa tttcttaaag tatttagaaa
    33061 tttgttagaa taggaaataa atgtttgaaa gatgctatcc gtgaatacta ttttagaaaa
    33121 attttataaa gaacaccaag tcaaaccctt catatcgcct gaacgagagt tggatacttg
    33181 gcttctaagt cccaagcgaa atatggactt attagtagat gattcactag caggagatat
    33241 cattttacta tggagaatcc agtttggtac ttttaccact gaaacatgat tttaaaaact
    33301 cccattcgaa tatgattcaa aattcgctta gaatcaatgt tttcccactt tttcaaaaaa
    33361 taaattttca tctaatttaa ataactttca attaagtgtg aattttgctt aaaatcatta
    33421 aaaaacaccc catggtgtga accatgaagt gttgtaaatg ctgtgttgta gctagttctt
    33481 agcgtttaga gaactggcta gctttacgag ctttcttaag atctggtttc caaaatactt
    33541 tgagtacact tatggtattg atgcccctaa acatctaaaa actctggtag aaaaagggta
    33601 tgctcttgtc gaaacttctt ttgactcact tgaccatcta aataatacca tgaaaaagaa
    33661 tatcctgaag aagaagggag ttactggact ttctaaaatg aaatcttgcg acctggatca
    33721 agcccttcat gagcattttt cagaagaaga attagctggt cactttcatg tccttctatg
    33781 gactttttta caatggcatt gctatcacac ccaataccta tctaagcgcc tggttcgtaa
    33841 actttattgc agctcttcct ctaaatttcc taattgttga accaattgcc cgttttatac
    33901 taagttcttt tcagaaacca tttactgggg aagaagttga agattttcaa gatgatgatg
    33961 aaatcccaac tattatctaa gccagttctg taaactacta atatttgaaa tccacttcct
    34021 tttagggtac aatggtataa atgaattttt gagaggatca gaatgaaaaa actagcaacc
    34081 cttcttttac tgtctactgt agccctagct gggtgtagca gcgtccaacg cagtctgcgt
    34141 ggtgatgatt atgttgattc cagtcttgct gctgaagaaa gttccaaagt agctgcccaa
    34201 tctgccaagg agttaaacga tgctttaaca aacgaaaacg ccaatttccc acaactatct
    34261 aaggaagttg ctgaagatga agccgaagtg attctccaca caagccaagg tgatattcgc
    34321 attaaactct tccctaaact cgctcctcta gcggttgaaa atttcctcac tcacgccaaa
    34381 gaaggctact ataacggtat taccttccac cgtgtcatcg atggctttat ggtccaaact
    34441 ggagatccaa aaggggacgg tacaggtggt cagtccatct ggcatgacaa ggataagact
    34501 aaagacaaag gaactggttt caagaacgag attactcctt atttgtataa catccgcggt
    34561 gctcttgcta tggctaatac tggtcaacca aacaccaatg gcagccagtt cttcatcaac
    34621 caaaactcta cagatacctc ttctaaactc cctacaagca agtatccaca gaaaattatc
    34681 gaagcctaca aagaaggtgg aaaccctagt ctagatggca aacacccagt ctttggtcaa
    34741 gtgattgacg gtatggatgt tgtggataag attgctaagg ccgaaaaaga tgaaaaagac
    34801 aagccaacta ctgctatcac aatcgacagc atcgaagtgg tgaaagacta cgattttaaa
    34861 tcttaaaaac caaaaaaata cagtatccac attcggtact gtatttcttt tactctcatt
    34921 cttaagttaa attattaaaa tcccatattt ggtctatcca gccttcataa aagtctggct
    34981 cgtggcagac cataaggata gatcccctat attctttgag agcgcgtttg agctcatcct
    35041 ttgcatccac atccaaatgg ttggtcggct cgtccagcac taaaacgttg ttttcacgat
    35101 tcatcaagag acagaaacga accttggctt gctctccccc tgataatact tgaatctggc
    35161 tttcaatatg tttggttgtc aaaccacaac gggcaagggc tgcacggact tctgcttgat
    35221 taagggcagg aaaggcattc cagacagctt caagaggagt ttggcgatta ccaccttcta
    35281 cttcctgctc aaaataacca agttctaaat aatctccacg ctccacttcc ccagcgattg
    35341 gcgagataat gcctaagaga ctcttcaaga gagttgtttt tccaatacca ttagcaccaa
    35401 taatcgcaac cttttgattg cgttcgaagg taagatttaa aggcttagta agaggacggt
    35461 cgtaaccaat ttgcaagttc ttggcttgga agataaagcg ccctggtgta cgagctggtt
    35521 tgaaatcaaa ggatggtttt ggtttctcac tttggagttc gataatatcc atcttatcca
    35581 atttcttttg acgagacata gccatattac gagttgcaac acgggcttta ttacgagcca
    35641 caaagtcctt gaggtctgca atctctttct gctggcgttc gtaggctgcc tctagctgag
    35701 atttcttcat agcataaact tcttggaact ggtagtagtc accagagtaa cgcgtcagct
    35761 gttgattttc cacatgatag acaatattaa taacgtcatt gaggaatgga atatcgtgcg
    35821 aaatgagaac aaaggcattc tcatagtttt ggagatagcg cttgagccaa tcaatatgct
    35881 cagcatccaa gtagttggtc ggctcgtcca acagcaagat atcaggcttt tcaaggagaa
    35941 gttttgccaa aagcaccttg gttctttgcc cacctgacaa agaagttaca tccgtatcca
    36001 tgccaaagtc cataacacca agagcacgcg ctacttcgtc aatcttagca tccaaggtat
    36061 agaaatcacg actctccaga cggtcttgaa gttctcctac ttcttccatg agagcatcaa
    36121 catccgcgcc gtcttcagcc attttcatat agaggtcatt gatacgagct tcagctttga
    36181 aaagctcatc aaaagccgta cggagaacat cacgcaccga ctgtctttca gcaaggacag
    36241 agtgctgatc caagtaacca gccgtcacat atttggacca ctcaaccttt ccttcatctg
    36301 gcagcatttt accagtcacg atactcataa aggttgattt tccttcacca ttggcaccga
    36361 ccaggccgat atgttctccc ttgaggagac ggaaggacac atcttcaaaa attgcacggt
    36421 caccaaaacc gtgactcaga tttttaactt ctaaaatact cattttaatt ccttatcttg
    36481 tttttatgta atcgtttata aaggagccaa gccagatagc cacccaaagt attggtccac
    36541 aaatcatcaa tctcaaagac gcgattgaaa tcaaagaaaa agtccaagat taattgcgta
    36601 cactcgattc caagactcac aagaaaacta aaaagaagga ccttttttgt tttccgcaaa
    36661 tttggaaata gataaaggag ttggaaaatc agaggaaaaa acaagaagac attgaggaca
    36721 ttttgtaaaa aaatccaaca taattgtcca atgtcactca cttcgcccag tttccagaga
    36781 gaattgaaag gagtcaaaag aaaaaccagg cgtccaagat gctgaatacc tggagttccc
    36841 actcccacgg tagattgttc ttgaggagta aagcaaaaac agacaatgca aatgctatag
    36901 aaaatgactc cccagaccaa aatatgatta taagtcttct tcatcattaa ggatttaccg
    36961 ctgcgactgc cttctggcgg tcacgtttca ttgtgttaga gcgcaattgt ccacaagctg
    37021 cgtcaatatc tgtaccatgc tcttgacgaa ccacacagtt gacccctttt ttcttaagcg
    37081 tatcatagaa agccaacacg cgctctttgg gactacggct atattggtca tgctcactaa
    37141 ctgggttata aggaatcaag tttacataag acaatttctt gatgttcttg agcaattcag
    37201 ccaattccaa ggcttgttct acaccgtcgt tgacttcatt aagcatgata tattcaaagg
    37261 ttacacgacg gtttgttgtc tcaatgtagt attcaatagc agcaaagagt ttttcaatcg
    37321 gaaaggcacg gttaatcttc atgatacttg aacgaagttc attgttgggt gcgtgaagag
    37381 acacggcaag attgacctga accccttcat cagcaaagtc acgaatttta tgagccaaac
    37441 ctgaggttga aaccatgatg tgacgagcac cgatagccat tcctttatca tcattgatag
    37501 tacgaaagaa attcaagaca ttgttgtaat tatcaaaggg ctcaccgatt cccatgacaa
    37561 cgatatggct gacgcgttca tcctgaccac gctcatcaaa gtatttctga accagcatga
    37621 tttgcgctac gatttcaccg ttattgaggt cacgttgctt cttaatcaaa ccagaggcac
    37681 agaaggtaca accgatatta cagccgacct gagtggtcac acagacagat aaaccatagt
    37741 gttgacgcat gagtacagtc tcaattaaca taccgtcggg caattcaaag agatatttga
    37801 ctgtaccatc agcagactct tgcacaatac gttgtttcaa gggattgacc acaaactggt
    37861 cattgagctt agcaatcaaa tccttggaaa ggttggtcat ttcttcaaat gactgcacac
    37921 gtttacggta gagccattcc cagatttgat ctgcacggaa tttcttttct ccctgctcca
    37981 atacccattc ctgcatggtt tgatgtgcca aactatgaat tgagggtttc atttcttctc
    38041 cttattctct actcacttct gacgaatgac aaaatgacgt tgtcccttgt cctctttctg
    38101 agaatgctgg tctttctgac gacgtctatt cttcttatct gcattcgact ttcgtttagt
    38161 ttgagtcggt ttctttcctt ttctagaagg tgtttcttct tccgtcttac gcattttctt
    38221 gtcaaatgat gctcgcttag gggcttcatt ttctaagaca aaataggcac aaccataact
    38281 acaatactct aaaaggtagt cttgtaaacg actgattttt tcaagttttt cttctgttcg
    38341 gtcatccttg taaaaacctc gtaggcgaag ctgttcgttg ctccagtccc ccacgatata
    38401 atcaaacttg gttaatactt ctgaaaaacg ctgattaaaa gtcgtcacat caaaggcatc
    38461 cttgatattt tcaaccaagg aaaaagctat cccttccgtt tcgaccttgt ccccgtgtaa
    38521 atggaactcc ggaccaggaa acttgttata gttgtataat tcaggtgcaa tttcttttcg
    38581 catagatatc cttttttcac gattacttaa tactttattc taccataatt tctagcagtt
    38641 agcacgtttc tcataaaaat gaaaaaagtc taacgatttt gtcagaccag aatcttataa
    38701 cctaaaaaag agaagaacaa ttcttccctc caactatcat tatttagcag ctgcgtacaa
    38761 ttcatctact ttattccagt tgattactga aaagaaagct ttgatgtagt caggacgcac
    38821 gttgcggtat ttcacgtagt aagcatgttc ccaaacgtcc aagcccaaga ttggtttttt
    38881 accttctgag attggtgtgt cttggtttgc tgttgaagtc acttcaagtt ttccttcttt
    38941 gttgacaacc aaccatgccc aacctgaacc aaaacgagtt gttgctgctg cagtgaaggc
    39001 tgcttggaat tcttcaaatg aaccaaatgt tgcatcgatt gctgctgcca gttctgctga
    39061 aggagctgtt ttctcgggag tcatcaattc ccagaaaaga gcgtggttca agtgtccgcc
    39121 accattgttg ataagtgctt gacggatatc agctgggata gattctacat cagcaagcaa
    39181 ggcttcaagg tcttcaccga tttcagggtg tttttctaaa gctgcattgg cattgttgac
    39241 ataagtttga tggtgtttgt catggtgcaa atgcattgtt tccgcatcga tgtatggttc
    39301 caaagcgtcg tatgcatatg gaagttctgg taagataata gccatctgta atacctcttt
    39361 ttctttctat atgaaaatga taacgcaaac attcactttt ttcaagtttt ttgcttatag
    39421 ataaggaaat cactgacata ctttctaata aaataagcaa atcagcaaga aacccacgac
    39481 aagataatcc tgatgcgggt tgtagtttca acaaatgtca attgacctga ctagcaatct
    39541 gtaagagtgc cttttcaaaa aggaaacctt tttcataaag acctgtctta atctgatagt
    39601 ctgtctcaat caaataggaa atagcttgct tcagaaagct caaagaaagt cctctcgaat
    39661 ctcttaatgc aaacttgatt tgataaggat ttgggttacg tcccagataa ctacctaaac
    39721 tacttgcaat ctgcgattct gtttggccag actccgccaa aatcttcacc tgagtaaaag
    39781 tccgaaattg tcccagcatg actgcaatca gtttgatttc atcttcccct tgcaaggtca
    39841 agtctctcac caaatcgcgc gcctgatcca tctttttagt cagaataaac tgagttaaat
    39901 caaaaatatt gtcctgcaag gtcttgggaa ttgcgttaac aatatcctct tcctcgataa
    39961 cagaatccgc cttataggac tgtaaaaaga gaagattttt ctggatttcg ctaaattgaa
    40021 accccgactt gatgaggaga ttttcaaaag aatgattggt aaactgcaga ccttgtttct
    40081 gactccactt ttggaagtac tggcgcaatt cttgttcttt tacttctact gcatcgaagg
    40141 ccttggcatc acgcttaagt aatttgacta accgtctttt gctatccagc tttccttctg
    40201 caaagattat caacttggtt gttggagaag gattgtcaag gtattcctca aatgacttaa
    40261 gctcatcatc tgtcaaaaag cgtttcttag cagtcgtgat atccataaaa taatctaata
    40321 tcacgatttt ctcatccgca aagaaaggaa ggctgaccaa ctccagttcc acatccttgt
    40381 aaactacttc tttcatatca aagtaggcaa agttgaggtc agcagaatca tacccaatct
    40441 gtttcaacac ttgactcttc atcacttcaa actgcccctg atctgtccct gtaaataggc
    40501 tcaggctcgg taaatttgat aaagtcaact tctgactttc ttcaatggct agcatcgtct
    40561 ctcctttctt cagatttttc gatttaattt agtcaatata gcgcaatttc ccacggaaat
    40621 cttctaagct ctcgtagcct ttttccacca tgattgcttt cagttcattg gtaatgcggt
    40681 caaaagcact gacgccttct ttgtgaaggg tcgttcccac ctgcaccata cttgctccac
    40741 agaggatgtg ttcaaaggca tctcgaccag tcagaacgcc acctgttccg ataatttgga
    40801 tttgaggatt taaacgttga taaaaggcgt gaacattggc tagagcagtc ggtttgatgt
    40861 attctccacc aattccacca aaaccattct taggccgaat aacgacagat tcgtcttcta
    40921 tatagaggcc gtttccgata gagttaacgc agttgacaaa cttgagcgga tatttgttga
    40981 aaatagctgc cgcttgatca aagtgaacaa tatcaaaata aggtggcaat ttaattccaa
    41041 gaggtttggt gaagtaagca aacacttctg ccaaaatccg gtctgttgtc tcaaaatcat
    41101 aggcaatctg aggtttacct ggaacatttg gacaggaaag atttagctca gtcagaccac
    41161 gaaaatcact ctcttggact tttttcaaaa tagtatgggt ttcctctgga gacatgccga
    41221 ccagagataa gaagaaagtt cggttcgact ctttttcctg caaatctaaa agataatcca
    41281 aataatagtc taagccatta tttggcaagc ccatagagtt gatggaacca agtggaacat
    41341 cttggtagcg tggctcagga ttcccctgac ggaagtccaa ggtcgctgtc ttagtaacaa
    41401 aggttcctgc cgctgagttt ttgacctctt ctaactcctc tatcgtcata caagccacac
    41461 ctgctgcatt catcaagcaa ttgtcaaact caaaaccagc aatttgtgtt ttcgttgata
    41521 ccatgattct aatcctccag atttctttta ttgctaatat tataccataa ttttaattct
    41581 aggtttacta gattctgtgg ttctatctat ttattcggaa aagaaagtct agtacagaag
    41641 tcatgctatg gaaacagcta gtatattgga agtttgaaca aggcttgggt aacagacttt
    41701 tgaatgaagt ccaagcaaca aggagaaatc tcaaccatga gtccattcca tgactctgtt
    41761 gctctagaaa accttgcaat agtcaagtga taacgaataa aactttggat tgaaatatct
    41821 ccatgattat ctattacgag gagaaatctc aacctttatc atttttaaag aaatatagta
    41881 aaatgaaaca agaacaggag aaatcgatca ggacagtcaa atcgatttct aacaatgttt
    41941 tagaagttga agtgtactat tctagtttca atctactata catgtaaatc tctactttcg
    42001 caaaatggat tttcagaaca gtatcccaat atagttaaaa actataaaaa agagaggacg
    42061 ttcccctctt aaaatcttat tttactgctt ctttcaaagc atctacctta tccaaacgtt
    42121 cccatggaag atcaatatct gtacgtccca tgtgaccgta agccgatgtt tgacggtaaa
    42181 ttggacgctt gaggtccagc atttggataa tccctgcagg gcgaaggtca aagatttgac
    42241 gagccgcttt ttcaagttga ctttcagcta ctgttcctgt accgaaagta tcgatacgaa
    42301 cagaaacagg ttgcgcaaca ccgatagcat aggccaactg cacttctgcc ttcttagcaa
    42361 ggcctgctgc aacgatattc ttggcaatat agcgagccgc ataagaggct gaacgatcca
    42421 ccttagtcgc atctttacca gagaaggcac caccaccatg acgagagtag ccaccataag
    42481 tatctacaat aatcttacga ccagtcaaac ctgagtcccc ttgaggacca ccgattacaa
    42541 aacgacctgt cggattgata aagaattttg tcttatcatc aagataagaa gatggaataa
    42601 cttctttgat gaccttgtca atcacatctt gatggatttg ttcattagtg gcctctggat
    42661 catgctgagt agaaataacg actgtatcta cacgtaccgg acgatcattt tcatcgtact
    42721 caactgtaac ttgtgatttt gcatctggac ggagatagct aatttctcca gacttacgaa
    42781 gttctgccag acgacgaacc aatttatgac tgagtgcaat tggcaatggc atgagctctt
    42841 ctgtttcatc tactgcaaat ccaaacatga gcccttggtc acctgctcca atcaagtcca
    42901 gtggatcttg atcagcattt ccacgaacct ccaaggcttc gttaacacct tgagcgatgt
    42961 caggagattg ttccaccaaa gatgggtgta ctcccaccgt ctcagcagaa aatccatatt
    43021 ctgtattggt ataaccaatc tctgcaatgg tatcacgaac cacacggtta atatccacat
    43081 aggcatttgt agaaatttca ccaaaaacgt ggacagaacc agtatataca gctgtttcag
    43141 cagcaacgtg cgcctctgga tcctttgcta aaatagcatc caaaatcgca tctgaaattt
    43201 ggtctgcaat cttatccgga tgcccctcag atacagattc agacgtgaat aatttacgtt
    43261 ctgacataaa aatgtccccc cttaaaaaat attgttatag agttacaaag tactgatagg
    43321 aaaactcttt gtaataaata cctaccatct tatcgggact atataacttt atcattatac
    43381 catttttaat cgcaatttgc agtctttaat gtagtgtttc ggtttagata gttcgttctc
    43441 ataaataaaa aagttggagc tcaatactcc aacaatttct attaaaatgt ttggcgttta
    43501 gctttacgct ctgcacgacc gcgagcgcga ttttcagcac gcttggtttt acggcgcttt
    43561 tcatcaaccg cccattgaat tttcttctta taacccggtt tgactttttt ctttttcttt
    43621 ttaaccaaac caatcatttc gatatcaagt ttatcttgtt ttttctcacg gttagcacga
    43681 cgatcacggt cataggtatc ttgaaattcc ccgtctttga ccatcttagg actaaacttg
    43741 attcccaatt tctccaactc acggatatcc gagtcatcac ttggctgata aagggtaata
    43801 gctgtacctg gtaggccatt tcgtccagta cggccaacac ggtgaacaaa aaaagataag
    43861 tcttgcggaa tggcatcatt gatgacatgg ctgacacctt caatgtcaat cccacgcgct
    43921 gccaaatctg ttgcgacaat atactcaaaa tccagatttt gcacctgatt catgattcgc
    43981 ttgcgttcac gaggggcaat atcgccatgg atttttgcaa ccttcaagcc ttgagcagtc
    44041 agatatgaat gcaattcatc agcacgcgtt ttagtgttaa caaaaatcat tgccaaatac
    44101 ggctgcatca actgagtcaa ctggtaaatt tgagcattct tatcatgtcc cttggtcgaa
    44161 atcaaccaat tatcaatggt gtcagaaata accgttttag tcttaatttt ctccataaca
    44221 ggatttgata agtatttttt caagaatggt tgcagttttt gtgggatagt cgctgagaag
    44281 accatgaatt gcaagtcttt tggaagactg ccagcaatct tatcaacagt ttccaagaat
    44341 cccatatcca aggtcatatc tgcttcatca acaacaaatg tcttggcttt atgaatagct
    44401 aaatcaccag atttaaccaa gtcgtagata cggcctggtg ttccaataac aatatgaggc
    44461 tgattgcttg ccaatttctc aatctggcga gccttatccg taccacccac ataattaacc
    44521 acacgaactt cgacatctga gtgagctgaa atctgacgcg ctacttggta aatttgagta
    44581 gccaactcac gactcggtgc agtaatcact gcttgtacac tatcgctagc ttcatctaat
    44641 tgctggaaaa tcggtaacaa gaaagtgtga gtcttacctg aacctgtttt tgattctcct
    44701 actaggtcac gacctgccaa aacaatagga atcaacttgt cttgcacctc tgttggagtt
    44761 gtaaatttta actccttcaa ggcttctcta atatagtttt taaattgaaa tttcgtaaat
    44821 gacataacat cctcgattct atctatctta tcaattatac catattttga acattttcag
    44881 tagtccgact catctgacct atcacaaggc tctcaatttc tctaaatata gtaaaatgaa
    44941 ataagaatag gatgaatcga tcaggacagt caaatcgatt tctaacaatg ttttagaagc
    45001 agaggtgtac tattctagtt tcaatctact atacctctct tatactaaaa atcatacatt
    45061 tgctttcttt ccaaaatgca aaaagagaag accaaattgg tcttctctca gccttaaagc
    45121 ttgcgactca gatagatttg tcaaacagtc aaacagttgc ttaagaatct tgtaaaagtc
    45181 gaaagcttct agaaaaatta gtacttaatc atctttccgc ttgcgaccaa gaagcaacac
    45241 tgctagacct gcaagaagag agctagtcac tagtccagtg agtgaaagtg gtgcagtact
    45301 acccgcattt ggcaatgtag cttgtttttc cttttctcct gctggacctt gagctggtgg
    45361 attctcttca ggttttcttg gttgttctga ttgatgtcta tctgcctgat tattatcagt
    45421 tccctgctct ccccctggat tcactggtgg aactggattt ggttgaggtg ctggttgtgg
    45481 cgttggtgcc ggctgtggtt gtggactagg atcttgctta gcttcaaaga cccacttacc
    45541 gacgaaggtt agatttgacc cctcttccac ttcttggtaa cctaagaatg tccatgtacc
    45601 atttgcaaca gcaacttcta caggcatcgg tgcttctgga acgaaagcaa tcgctacaga
    45661 agaacttgta gtatatgttc cactttgtgg gagtaagctc aatacttctg ctggcaagtt
    45721 gttgtctgcg gttgcacttt cgaagcggta agtcacctta taggtttgag tt
//
LOCUS       DAVLMQ010000012        42366 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000012 DAVLMQ010000000
VERSION     DAVLMQ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42366
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.012"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..71
                     /locus_tag="VXF95_000802"
     CDS             <1..71
                     /locus_tag="VXF95_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1081382.1"
                     /translation="IPAMSAPVFDNIEAAIKEHGLS"
     gene            119..1594
                     /locus_tag="VXF95_000803"
     CDS             119..1594
                     /locus_tag="VXF95_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HEV1081383.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVVFLVLYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1620..1697
                     /locus_tag="VXF95_000804"
                     /pseudo
     CDS             1620..1697
                     /locus_tag="VXF95_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            1899..8600
                     /locus_tag="VXF95_000805"
     CDS             1899..8600
                     /locus_tag="VXF95_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HEV1081384.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKPEEKAPRIESQASNQEKPLKEDAKAVTNEEVNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIVNTDDKDHELVAEYQIVERGGHAVTGLVRTESRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDSQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLGTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELSVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDSWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPVVPTV
                     TVGGEAVTGLTSRQPMQYRTLSYGAQLPEVTASAENADVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKSGAVTLNAEYEGAKGQVELTIQANTEKKIAQSIRP
                     VNVVTDLHQKPTLPTTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARAKVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLYFT
                     KDKNLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLSVEWEEVPAEN
                     LTKAGQFTVRGHVLGSDLVAEVTVRVTDKLGEALSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDYSENRRWTNWSARPSTNPEVSAGVIFRENGKIVERTVAQAKLHFFA
                     DSGTDAPSKLVLERYVGPGFEVPTYYSNYQAYESGHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKAVKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGDDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVATVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKVGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSAASQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(8847..9703)
                     /locus_tag="VXF95_000806"
                     /pseudo
     CDS             complement(8847..9703)
                     /locus_tag="VXF95_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014125496.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(9915..10274)
                     /locus_tag="VXF95_000807"
     CDS             complement(9915..10274)
                     /locus_tag="VXF95_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HEV1081385.1"
                     /translation="MGMILMKLASILLLILTLVVCIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLALSFLAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYIEMIVELFLMK"
     gene            10366..11322
                     /locus_tag="VXF95_000808"
                     /pseudo
     CDS             10366..11322
                     /locus_tag="VXF95_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11306..11863
                     /locus_tag="VXF95_000809"
     CDS             11306..11863
                     /locus_tag="VXF95_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1081386.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            11856..12110
                     /locus_tag="VXF95_000810"
     CDS             11856..12110
                     /locus_tag="VXF95_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081387.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERSVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12122..14176
                     /locus_tag="VXF95_000811"
     CDS             12122..14176
                     /locus_tag="VXF95_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HEV1081388.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRNRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEESKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKNKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETTIISSGAFVERVINRVKPNNIN
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14355..15215
                     /locus_tag="VXF95_000812"
     CDS             14355..15215
                     /locus_tag="VXF95_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HEV1081389.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLGFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNLSNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15426..16136
                     /gene="ccdA2"
                     /locus_tag="VXF95_000813"
     CDS             15426..16136
                     /gene="ccdA2"
                     /locus_tag="VXF95_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1081390.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLVFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGFLVLFGNASILSQLFE"
     gene            16156..16722
                     /locus_tag="VXF95_000814"
     CDS             16156..16722
                     /locus_tag="VXF95_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HEV1081391.1"
                     /translation="MKKWQTCVLGAGSLLCLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16733..17845
                     /gene="msrB"
                     /locus_tag="VXF95_000815"
     CDS             16733..17845
                     /gene="msrB"
                     /locus_tag="VXF95_000815"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HEV1081392.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
     gene            18113..18850
                     /locus_tag="VXF95_000816"
     CDS             18113..18850
                     /locus_tag="VXF95_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081393.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
     gene            18847..20538
                     /locus_tag="VXF95_000817"
     CDS             18847..20538
                     /locus_tag="VXF95_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1081394.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            20654..21217
                     /locus_tag="VXF95_000818"
     CDS             20654..21217
                     /locus_tag="VXF95_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HEV1081395.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            21239..26941
                     /locus_tag="VXF95_000819"
     CDS             21239..26941
                     /locus_tag="VXF95_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1081396.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQLPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPRTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEEGKEGQAPVQEVNPEYKVTTGTVEKSTESELDFTTEV
                     VPDDTKYVDEEVVERQGSKGVQVTKTTYETVEVVETDKVLSTTTEVKTPVVPKVVKKG
                     TKPVEGTAVETREEVIPFATKEQEDGTLKRGTRQVAQEGVNGKKQITETYKTIRAEKT
                     NEAPTVEETVLQAPQDEIIKKGTKGLEKPTLEWVKTDKDVLKKSATASYTLNKPDGVE
                     IKSIKVALKDNTGTVIKEVTVEENNLNVTLDNLKYYQGYTLSTTMVYNRGEGEETETL
                     EDKEVQLDLKKVEIKNIKETSLMSVDDAGVETDKSLLTEKPTDVAPLYLRVTTHDNKV
                     TRLAVDKIEEVEEDGKTLYKVTAKAPDLVQRNADNTLSEEYVHYFEKQLPKIGNVYYN
                     FNELITDMQKTPNGEFKLGADLNAVNVPTPNKSYVTAKFTGKLYSEGDKHYTIHNLAR
                     PLFAQAENAHIHDINLGNVNINMPWANKTAPLGEMFKKSTIENVKVTGNVVGNNDVTG
                     MVNKLDESDMRNVAFIGNITSVGSAGWWSGGLVSESWRSNTDNSYIDTTIKGNKAKVG
                     GLIAKLNHGADPRDVGARGRLKNSVAKGTIDVRDPQETGGLLHSNWSWGLAENNITMM
                     KVKNGGEILYGSRDAEDDDYFGANWVRNNNAFVNGISEGKQSYSRSSRWKGISEDEAK
                     TRIAKMGITAHEYEITQHLTDKLNRAAFKEDTYKTTQDYKTERELAYRNIEKLQPFYN
                     KEWIINQGNKLTDGSNLMIKEVLSVIGMKNGQFVTDLSDIDKIMIHYADGTKEEKTVT
                     RKADSKVQQIREYSVEGLGDVVYTPNMVEKDRAQLITDIKAKLDSVQLISPEVRNLMD
                     KRGKAHENTDERRNGYIRNLFLEESLDEVKGNLDKLVKALVENEDHQLNGDEAAMKAL
                     VKKVEDNKAKIMLGLAYLNRYYGFKYDEKSMKDIMMFKPDFYGKNVSVLDFLIRVGSR
                     EHNIKGNRTLEAYREVIGGTIGIGELNGFLNYNMRLFTEETDINTWYKKAVSHTNYIV
                     EKQSSNPAFANKKYRLYENLNNGEHGKYILPLLTTKKAHMFLISTYNTLAFSAFEKYG
                     KNTEAEREAFKKEIDLRAQEQINYLDFWSRLAADNVRDRLLKSENMVPSAIWDNQEVP
                     GHGWADRMGHNKNGDYAPVREFYGPTGKWHGYNGTGAYAYIFTNPQNSEAVYYIISSM
                     ISDFGTSAFTHETTHINDRMAYLGGWRHREGTDVEAFAQGMLQSPAVSSPNGDYGALG
                     LNMAYKRENDGNQWYNYDSNKLDSRAKIDHYMKNYNEALMMLDHLEADAVIAKNNGDN
                     NKWFKKMDKKWRENANRNGLVGQPHQWDLLRDLNEEENKKKLTSIDDLVDGNYVTKHN
                     MPGNKHYRAEGFDTAYQTVNMMAGIYGGNTSKSAVGSISFKHNTFRMWGYFGYLDGFV
                     GYASNKYKDAANKENKGLLGDDFIIKKVSDGKFDSLEAWKKEWFKEVKAKGEKGFVAI
                     EIDGKTITNYAELRELFDKAVEADLKAGNSNQTVALKEKVYKQLLQKSDGFVGNLFKA
                     "
     gene            27016..28737
                     /gene="pabB"
                     /locus_tag="VXF95_000820"
     CDS             27016..28737
                     /gene="pabB"
                     /locus_tag="VXF95_000820"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HEV1081397.1"
                     /translation="MHRKTVIDFRTLGERYTFTQPIKELKTRNVEEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKVPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANRDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGELLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQHLLETGQVEEKVLTLADLTQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            28738..29355
                     /locus_tag="VXF95_000821"
     CDS             28738..29355
                     /locus_tag="VXF95_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1081398.1"
                     /translation="MKLIFLHGLGQSAESWKEVRNLLTDYPSEAIELFPSGVSNYQQA
                     KERVYQHLAQETEPFVLIGLSLGAALTLELSSYDLPNLRALILSGCPLKLAGNILFYL
                     QLLIFKLLPKRVFEKQGADKTLMVGVSEELKTLDLTDIAGTCSYPTLLICGSKDKPNL
                     SSMKALHRLLTDSQFQIIPDGPHVLNKAKPKEFVEKTRSFLELLK"
     gene            29405..30395
                     /locus_tag="VXF95_000822"
                     /pseudo
     CDS             29405..30395
                     /locus_tag="VXF95_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042500.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            30530..31489
                     /locus_tag="VXF95_000823"
     CDS             30530..31489
                     /locus_tag="VXF95_000823"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HEV1081399.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDRDKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPIACTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENTFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            31587..32426
                     /locus_tag="VXF95_000824"
     CDS             31587..32426
                     /locus_tag="VXF95_000824"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HEV1081400.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(32474..32644)
                     /locus_tag="VXF95_000825"
     CDS             complement(32474..32644)
                     /locus_tag="VXF95_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HEV1081401.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            32765..33649
                     /gene="miaA"
                     /locus_tag="VXF95_000826"
     CDS             32765..33649
                     /gene="miaA"
                     /locus_tag="VXF95_000826"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HEV1081402.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKRFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIQSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPYEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            33642..34880
                     /gene="hflX"
                     /locus_tag="VXF95_000827"
     CDS             33642..34880
                     /gene="hflX"
                     /locus_tag="VXF95_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HEV1081403.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            34873..35496
                     /locus_tag="VXF95_000828"
     CDS             34873..35496
                     /locus_tag="VXF95_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HEV1081404.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGFGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            35511..36440
                     /locus_tag="VXF95_000829"
     CDS             35511..36440
                     /locus_tag="VXF95_000829"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HEV1081405.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            36461..37216
                     /locus_tag="VXF95_000830"
     CDS             36461..37216
                     /locus_tag="VXF95_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1081406.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(37270..38178)
                     /locus_tag="VXF95_000831"
     CDS             complement(37270..38178)
                     /locus_tag="VXF95_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HEV1081407.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            38242..38511
                     /locus_tag="VXF95_000832"
     CDS             38242..38511
                     /locus_tag="VXF95_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HEV1081408.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            38511..38891
                     /locus_tag="VXF95_000833"
     CDS             38511..38891
                     /locus_tag="VXF95_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1081409.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNKEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            38980..39207
                     /locus_tag="VXF95_000834"
     CDS             38980..39207
                     /locus_tag="VXF95_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081410.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(39247..39972)
                     /locus_tag="VXF95_000835"
     CDS             complement(39247..39972)
                     /locus_tag="VXF95_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1081411.1"
                     /translation="MRLDNLLAQEKISRKAMKQALLKGDILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTSLKRIQFGDFTLNPDLA
                     EGNYRPLNQKELQIIKNYLEMSR"
     gene            40134..41975
                     /gene="typA"
                     /locus_tag="VXF95_000836"
     CDS             40134..41975
                     /gene="typA"
                     /locus_tag="VXF95_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HEV1081412.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            41995..42249
                     /locus_tag="VXF95_000837"
     CDS             41995..42249
                     /locus_tag="VXF95_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HEV1081413.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
BASE COUNT        12956 a         7918 c         9514 g        11978 t
ORIGIN      
        1 gtatcccagc aatgagcgct ccagtatttg acaatattga agcagctatt aaagaacatg
       61 gattaagcta attctaattt gttaacattc atataacata aaaaagggag gaactgttat
      121 ggatgcaatc tttgacctaa tcggaaaggt tttcaatccc atcttagaaa tgggtggacc
      181 tgtcatcatg ttaatcattt tgacagtatt ggctttactt tttggagtga aattctccaa
      241 agcgcttgaa ggtggtatca aacttgccat cgctcttaca ggtatcggtg ctatcatcgg
      301 tatgctaaat ggtgctttct cagcatcact tgcaaaattc gttgaaaaca ctggtataca
      361 attgagtatt accgacgttg gttgggcacc acttgcaaca atcacttggg gttctgcttg
      421 gacactatac ttcttgctca tcatgttgat tgtcaacgta gtgatgcttg ctatgaagaa
      481 aaccgataca cttgatgtcg atatctttga tatctggcac ttgtctatca caggtctctt
      541 gattaaatgg tatgctgata acaatggtgt gagtcaaggg gtttcactct ttattgctac
      601 agcagctatc gtccttgtcg gtgtgttgaa aattatcaac tctgacttga tgaaacctac
      661 atttgatgac cttcttaacg ccccaagttc atcaccaatg acatcaactc acatgaacta
      721 catgatgaac ccagttatca tggttttgga taagattttt gaaaaattct tcccaggcct
      781 tgataaatat gactttgatg ctgctaaatt gaacaagaaa atcggtttct ggggatctaa
      841 attcttcatc ggtttcatcc ttggtatcgt tatcggtatt atgggaactc cacatccaat
      901 tgcaggtgtt gcagatgcag ataaatggcg tcttgttatc aaaggatggt tgtctcttgg
      961 tttgactgcc ggtgtatctt tggaactctt ctcacttatc ggttcatggt tcatcgcagc
     1021 cgtagaacca ctatcacaag gtattacaaa cgttgctact aaacgtcttc aaggacgtaa
     1081 attcaatatc ggtcttgact ggccattcat cgctggtcgt gctgaaatct gggcttgtgc
     1141 caacgtactt gcaccaatca tgttgattga agcagtgctt ctttcaaaag ttggaaatgg
     1201 tatcttgcca cttgcaggta tcatcgctat gggtgttact ccagctctct tggttgtaac
     1261 tcgtggtaaa ttgctccgta tgattatctt cggaacactc ttgttgccac tcttccttct
     1321 ttcaggtaca cttattgcac catttgcaac agaacttgct aaaggtgtag gtgccttccc
     1381 agaaggtgtg agccaaactc aattgattac tcactctact cttgaaggac caatcgaaaa
     1441 acttcttggt tggacaattg gtaacactac aactggtgat atcaaagcaa tccttggtgc
     1501 agtagtcttc cttgtattat atatcggtat ctttgcttgg tacagaaaac aaatgatcaa
     1561 acgtaacgaa gagtacgcag caaaagcaaa ataatgcgct cctataaaat ataaactcaa
     1621 tgaaaatcaa agagcaaact aggaagctag ccgcaggttg ctcaaaacac agttttgagg
     1681 ttgtagataa gactgacgaa gtcagctcaa aacatggttt tgaggttgta gatgaaactg
     1741 acgaagtcag taatcatatc tacggcaagg cgacactgac gaagtttgaa ttggattttc
     1801 gcagagtgta aattgttgaa actaggttgt cataccatgt atactacttg ggttttggca
     1861 gtagctaact gcactaaata taatataagg agggttttat ggggaaaggt cattggaatc
     1921 ggaaaagagt ttatagcatt cgtaagtttg ctgtgggagc ttgctcagta atgattggga
     1981 cttgtgcagt tctattagga ggaaatatag ctggagaatc tgtagtttat gcggatgaaa
     2041 cacttattac tcatactgct gagaaaccta aagaggaaaa aatgatagta gaagaaaagg
     2101 ctgataaagc tttggaaact aaaaatgtag ttgaaaggac agaacaaagt gaacctagtt
     2161 caactgaggc tattgcatct gagaagaaag aagatgaagc cgtaactcca aaagaggaaa
     2221 aagtgtctgc taaaccggaa gaaaaagctc caaggataga atcacaagct tcaaatcaag
     2281 aaaaaccgct caaggaagat gctaaagctg taacaaatga agaagtgaat caaatgattg
     2341 aagacaggaa agtggatttt aatcaaaatt ggtattttaa actcaatgca aattctaagg
     2401 aagccattaa acctgatgta gacgtatcta cgtggaaaaa attagattta ccgtatgact
     2461 ggagtatctt taacgatttc gatcatgaat ctcctgcaca aaatgaaggt ggacagctca
     2521 acggtgggga agcttggtat cgcaagactt tcaaactaga tgaaaaagac ctcaagaaaa
     2581 atgttcgcct tacttttgat ggcgtctaca tggattctca agtttatgtc aatggtcagt
     2641 tagtggggca ttatccaaat ggttataacc agttctcata cgatatcacc aaataccttc
     2701 acaaagatgg tcgtgagaat gtgattgctg tccatgcagt caacaaacag ccaagtagcc
     2761 gttggtattc aggaagtggt atctatcgtg atgtgacttt acaagtgaca gataaggtgc
     2821 atgttgagaa aaatgggaca actattttaa caccaaaact tgaagaacaa caacatggca
     2881 aggttgaaac tcatgtgacc agcaaaatcg tcaatacgga cgacaaagac catgaacttg
     2941 tagccgaata tcaaatcgtt gaacgaggtg gtcatgctgt aacaggctta gttcgtacag
     3001 agagtcgtac cttaaaagca catgaatcaa caagcctaga tgcgatttta gaagttgaaa
     3061 gaccaaaact ctggaccgtt ttaaatgaca aacctgcctt gtacgaattg attacgcgtg
     3121 tttaccgtga cagtcaattg gttgatgcta agaaggattt gtttggttac cgttactatc
     3181 actggactcc aaatgaaggt ttctctttga atggtgaacg tattaaattc catggagtat
     3241 ccttgcacca cgaccatggg gcgcttggag cagaagaaaa ctataaagca gaatatcgcc
     3301 gtctcaaaca aatgaaggag atgggagtta actccatccg tacaacccac aaccctgcta
     3361 gtgagcaaac cttgcaaatc gcagcagaac taggtttact cgttcaggaa gaggcttttg
     3421 atacttggta tggtggcaag aaaccttatg actatggacg tttctttgaa aaagatgcca
     3481 ctcacccaga agctcgaaaa ggtgaaaaat ggtctgattt tgacctacgt accatggtcg
     3541 aaagaggcaa aaacaaccct gctatcttca tgtggtcaat tggtaatgaa ataggtgaag
     3601 ctaatggtga tgcccactct ttagtaactg ttaaacgttt ggtcaaggtt atcaaggatg
     3661 ttgataagac tcgctatgtt accatgggag cagataaatt ccgtttcggt aatggtagcg
     3721 gagggcatga gaaaattgct gatgaactcg atgctgttgg atttaactat tctgaagata
     3781 attacaaagc ccttagagct aagcatccaa aatggttgat ttatggatca gaaacatctt
     3841 cagctacccg tacacgtgga agttactatc gccctgaacg tgaattgaaa catagcaatg
     3901 gacctgagcg taattatgaa cagtctgact atgggaatga tcgtgtgggt tgggggaaaa
     3961 cagcaaccgc ttcatggact tttgaccgtg acaacgctgg ctatgctgga cagtttatct
     4021 ggacaggtac ggactatatt ggtgaaccta caccatggca caaccaaaat caaactcctg
     4081 ttaagagctc ttactttggt atcgtagata cagccggcat tccaaaacat gacttctatc
     4141 tctaccaaag ccaatgggtt tctgttaaga agaaaccgat ggtacacctt cttcctcact
     4201 ggaactggga aaacaaagaa ttagcatcca aagtagctga ctcagaaggt aagattccag
     4261 ttcgtgctta ttcgaatgct tctagtgtag aattgttctt gaatggaaaa tctcttggtc
     4321 ttaagacttt caataaaaaa caaaccagcg atgggcggac ttaccaagaa ggtgcaaatg
     4381 ctaatgaact ttatcttgaa tggaaagttg cctatcaacc aggtaccttg gaagcaattg
     4441 ctcgtgatga atctggcaag gaaattgctc gagataagat tacgactgct ggtaagccag
     4501 cggcagttcg tcttattaag gaagaccatg cgattgcagc agatggaaaa gacttgactt
     4561 acatctacta tgaaattgtt gacagccagg ggaatgtggt tccaactgct aataatctgg
     4621 ttcgcttcca attgcatggc caaggtcaac tggtcggtgt agataacgga gaacaagcca
     4681 gccgtgaacg ctataaggcg caagcagatg gttcttggat tcgtaaagca tttaatggta
     4741 aaggtgttgc cattgtcaaa tcaactgaac aagcagggaa attcacactg acagcccact
     4801 ctgatctctt gaaatcgaac caagtcactg tctttactgg taagaaagaa ggacaagaga
     4861 agactgtttt ggggacagaa gtgccaaaag tacagaccat tattggagag gcacctgaaa
     4921 tgcctaccac tgttccgttt gtatacagtg atggtagccg tgcagaacgt cctgtaacct
     4981 ggtcttcagt agatgtgagc aagcctggta ttgtaacggt gaaaggtatg gctgacggac
     5041 gagaagtaga agctcgtgta gaagtgattg ctcttaaatc agagctatca gttgtgaaac
     5101 gtattgctcc aaatactgac ttgaattctg tagacaaatc tgtttcctat gttttgactg
     5161 atggaagtgt acaagagtat gaagtagata gctgggagat tgccgaagaa gataaagcta
     5221 agttagcaat tccaggttct cgtattcaag cgaccggtta tttagaaggt caaccaattc
     5281 atgcaaccct tgtggtagaa gaaggcaatc ctgcagcacc tgtagtgcca actgttactg
     5341 ttggaggtga agcagtaaca ggtcttacta gtcgacaacc aatgcaatat cgtactctat
     5401 cttatggtgc ccaattgcca gaagtcacag caagtgctga aaatgctgat gtgacagttc
     5461 ttcaagcaag cgcagcaaac ggcatgcgtg cgagcatctt tattcagcct aaagatggtg
     5521 gccctcttca aacctatgca attcaattcc ttgaagaagc gccaaaaatt gctcacttga
     5581 gtttgcaagt ggaaaaagct gacagtctca aagaagacca aactgtcaaa ttgtcggttc
     5641 gagctcacta tcaagatgga acgcaagctg tattaccagc tgataaagta accttctcta
     5701 caagtggtga aggggaagtc gcaattcgta aaggaatgct tgagttgcat aagtcaggag
     5761 cagtcactct gaacgctgaa tatgagggag ctaaaggcca agttgaactc actatccaag
     5821 ccaatactga gaagaagatt gcgcaatcta tccgtcctgt aaatgtagtc acagatttgc
     5881 atcaaaaacc tactcttcca acaacagtaa cggttgagta tgacaaaggt ttccctaaag
     5941 ctcacaaagt cacttggcaa gctattccga aagaaaaact agactcctat caaacatttg
     6001 aagtactagg taaagttgaa ggaattgacc ttgaagcgcg tgcaaaagtc tctgtagaag
     6061 gtatcgtttc agttgaagaa gtcagtgtga caactccaat cgcagaagca ccacaattac
     6121 cagaaagcgt tcggacatat gattcaaatg gtcacgtttc atcagctaag gttgcatggg
     6181 atgcgattcg tatagagcaa tacgctaagg aaggtgtctt tacagttaat ggtcgcttag
     6241 aaggtactca attaacaact aaacttcatg ttcgcgtatc tgctcaaact gagcaaggtg
     6301 caaacatttc tgaccaatgg accggttcag aattgccact tgcctttgct tcagattcaa
     6361 atccaagcga cccagtttca aatgttaatg acaagctcat ttcctacaat aaccaaccag
     6421 ccaatcgttg gacaaactgg aatcgtagta atccagaagc ttcagtcggt gttctgtttg
     6481 gagattcagg tatcttgagc aaacgctccg ttgataatct aagtgtcgga ttccacgaag
     6541 accatggagt tggtgcaccg aagtcttatg tgattgagta ttatgttggt aagactgtcc
     6601 caacagctcc taaaaaccct agttttgttg gtaatgagga ccatgtcttt aatgattctg
     6661 ccaactggaa accagttact aatctaaaag cccctgctca actcaaggct ggagaaatga
     6721 accactttag ctttgataaa gttgaaacct atgctgttcg tattcgcatg gttaaagcag
     6781 ataacaagcg tggaacgtct atcacagagg tacaaatctt tgcgaaacaa gttgcggcag
     6841 ccaaacaagg acaaacaaga atccaagttg acggcaaaga cttagcaaac ttcaaccctg
     6901 atttgacaga ctactacctt gagtctgtag atggaaaagt tacggcagtc acagcaagtg
     6961 ttagcaacaa tggcctcgct accgtcgttc caagcgttcg tgaaggtgag ccggttcgtg
     7021 tcatcgcgaa agctgaaaat ggcgacatct taggagaata ccgtctgtac ttcactaagg
     7081 ataagaactt actttctcat aaaccagttg ctgcggttaa acaagctcgc ttgctacaag
     7141 taggtcaagc acttgaattg ccgactaagg ttccagttta cttcacaggt aaagacggct
     7201 acgaaacaaa agatttgtca gttgaatggg aagaagttcc agcagaaaat ctgacaaaag
     7261 caggtcaatt taccgttcga ggccatgtcc ttggtagtga tcttgttgct gaggtcactg
     7321 tacgagtgac agacaaacta ggcgaagctc tttcagataa ccctaactat gatgaaaaca
     7381 gtaaccaggc ctttgcttca gcaaccaatg atattgacaa aaactctcat gaccgcgttg
     7441 actatctcaa tgacggagat tattcagaaa atcgtcgttg gacaaactgg tctgcaagac
     7501 cgtctaccaa tccagaagta tcagcaggcg taatcttccg tgaaaatggt aagattgtcg
     7561 aacggactgt tgcgcaagcc aaacttcatt tctttgcaga tagtggtaca gatgcaccat
     7621 ctaaacttgt tttggaacgt tatgtcggcc caggctttga agtacctacc tactattcaa
     7681 actaccaagc ctacgaatct ggacatccat ttaacaatcc agaaaattgg gaagctgtgc
     7741 cttatcgtgc ggataaagac atcgcagctg gtgatgaaat caacgtaaca tttaaagctg
     7801 tcaaagccaa agccatgaga tggcgtatgg agcgtaaagc tgacaagagc ggtgttgcga
     7861 tgattgagat gaccttcctt gcaccaagtg aattgcctca agaaagcact caatcaaaga
     7921 ttcttgtaga tggaaaagaa cttgctgatt tcgctgaaaa tcgtcaagac tatcaaatta
     7981 cctataaagg tcaacggcca aaagtctcag ttgaagaaaa caatcaagta gcttcaactg
     8041 tggtagatag cggagacgat agccttccag tacttgttcg cctcgtttca gaaagtggaa
     8101 aacaagtcaa ggaataccgt atccacttga ctaaggaaaa accagtttct gagaagactg
     8161 ttgctactgt acaagaagat cttccaaaac tcgaatttgt tgaaaaagat ttggcctaca
     8221 agacagttga gaaaaaagat tcaacactgt atctaggtga aactcgtgta gaacaagaag
     8281 gaaaagttgg aaaagaacgt atctttacag cgattaatcc tgatggaagt aaggaagaaa
     8341 aactccgtga agtggtagaa gctccgacag accgcatcgt cttggttgga accaaaccag
     8401 tagctcaaga agctaaaaaa ccacaagtgt cagaaaaagc agatacaaaa ccaattgatt
     8461 caagtgaagc tagtcaaact aataaagccc agttaccaaa tacaggtagt gcggcaagtc
     8521 aagcagcagt agcagcaggt ttagctcttc taggtttgag tgcaggatta gtagttacta
     8581 aaggtaaaaa agaagactag aaattttgat accttcttta tcattaaaga ccaaagaaaa
     8641 actcttgtcc taaatagaag ataaagagtc tgggacaaaa tagttctcaa ccacaaaaag
     8701 ctagagattt ccaattgcgg aactctagct ttttaatttt gagtcgttct cttattgtat
     8761 agtagattga aactagaata gtacacttct acttctaaaa cattgttaga aatcgatttg
     8821 actgtcctta tcgatttgtc ctgttcttat ttcatttcac tatattttag gaggttattg
     8881 gccataagta ccaatcccat gtcaattctc acttgacgct tccctctcag attacatctc
     8941 ttgtaaccca aacaagcctt tatctgccca aagacaggtt ccacatcaat cttgcgttga
     9001 gcgaaaatct gtctaccttg gggagataaa agcgcctgac attctttagc tttcaagttt
     9061 tgatagcgtt cgttcatata cagtcccttt tgagggactg attcaggttc atcagcgtag
     9121 taaaccttga tttcctgttg aaagtctgtc tgtgttttct ggtacttgat atggtgaaaa
     9181 cgatagcacc agccatcagg atgtgtgtag ctatcctcct tgtcattata gtgccaattc
     9241 gctaagtttt tagctgactg tttataccct ctcttttgtt tcttatcaaa catggcatat
     9301 ttaatcagaa ggggagtgat ttcttcttga aaatagacct gtatctgttc ttgaagtttg
     9361 gcggagaatt tctctgtcgt tttcttccac acaaaactat acttgttggc attggcttca
     9421 atcttagttc cgtcaataaa caaacaatct aaggtcacta actcttccat ttttcaattt
     9481 ttcgaccaga gaaaatccct tgtgaatagg caaatagaag agtagataca agcattttag
     9541 ggtgataaga cgggcgatca aaggcatgat aggaggtgta gaagtgacgt tcctccaagg
     9601 tattcaccac tttttcaata gtaaagacga gatggtcttg tggtaagaag gaactgattt
     9661 ctagtggtaa agttgtttga tttgtgttat agtgaatatg catgggatag cctttttaaa
     9721 tggtttatta agcaattcta ttttaccaag actatcgtaa ccatgcaaaa aaagcaacgg
     9781 caaatccgtt gctttttttg gagataagag actattgtcc cagcctcttt tctttgtata
     9841 aaattgtata gtgttattgt ctatactatt ttgtagagaa agcaaaaatc cctagaaaat
     9901 gcttagggat tcgactattt cattaagaac aattcaacaa tcatttctat atacatgata
     9961 agggttaata agaatcctgc acgccagaag aatttgataa atttaggata gtaaaagctg
    10021 cgttttttca aaaggaagaa aaagacgaga ataatggcta ggaacgagag ggctagcccc
    10081 agtctaggga ggaaattatg ggtaaaggtt ttagctgtaa tcaagtaata ctcaaatacc
    10141 aagactggaa aagccaaatc cgcaaagttt cgtcctagtt tttttaatct aaaaagtttg
    10201 gttaggataa tgcagacgac taaggtcagt atcaataata aaatagatgc taatttcatt
    10261 aaaatcatac ccatattgta tcataaaaaa aggctaatgg aaacgagaaa cagaggaatt
    10321 tataggaaag tcaggctttt gagattgtgg gtgatttttg ttataatgaa agttataaaa
    10381 tcttataata ccttgaatga ttattatcga aaactctttg gagaaaagac ttttaaagtc
    10441 cctattgatg cgggatttga ctgtcccaat cgtgatggaa ctgtggctca tggaggctgt
    10501 actttttgta cggtttccgg ttctggagat gccattgtgg caccagatgc gcctatccgt
    10561 gagcaatttt ataaggaaat tgactttatt catcgtaagt ggccagatgt ttagaagtat
    10621 ctggtttatt ttcaaaattt taccaacacc catgaaaagg tggaagttat tcgagagcgt
    10681 tatgaacagg ctatcaatga gccaggtgtg gtaggaatca atattggaac gcgcccagac
    10741 tgtttaccag acgaaaccat cgaatatttg gctgagttat cggagtgcat gcatgtgacg
    10801 gttgaattgg gcttgcaaac tacttatgaa gcaacctctg acctgattaa ccgtgcgcat
    10861 tcttatgaat tgtaggtgga aacggtcaag cgtttgagaa agtatccaaa aattgagatt
    10921 gtttcccatt tgatcaatgg tttgcctggt gaaacccatg agatgatggt tgaaaatgtc
    10981 cgccgttgtg tcacggataa cgatattcaa gggattaaac tgcatttgct ccatcttatg
    11041 acaaatactc gtatgcaacg agattaccat gaggggcgtt tacaattgat gagtcaggac
    11101 gaatatgtca gggtcatctg tgaccaactg gaaattattc ccaaacatat cgtcatccat
    11161 cgaattacag gagatgcgcc tagggatatg ctgcttgggc ctatgtggag cctcaataaa
    11221 tgggaagctc tcaacagcat tgagatggag atgcgacgtc gtggaagtgt tcaaggatgc
    11281 aaggctgtaa aacaggagtt tgaaaatgaa aagaccactt gagatggcac atgatttttt
    11341 ggctgaggtc gtgacaaaag aggatgtcgt agtggatgcg actatgggaa atggtcatga
    11401 cacgcttttt ttagccaagc tagccaagca agtctatgcc tttgatattc agaagcaagc
    11461 cttggaaaag acccaagagc gtttgcatca ggctgacttg acaaatgccc agttaatctt
    11521 gcaaggccat gagacactgg accagtttgt gataaaagct aaggcaggga tttttaatct
    11581 gggctatttg ccgtcagctg ataagtctgt catcacccga ccgcagacaa cgattgaggc
    11641 attagaaaag ctatgtggct tacttgtcaa aggtggacga attgctatta tgatttacta
    11701 tggtcatgaa ggaggcgatc tcgagagaga tgctgtcttg gattttgtga tccagttgaa
    11761 ccaacaagag tacacagctg ccatttaccg aactttaaac caagtcaaca acccgccgtt
    11821 tttagtgatg attgaaaaat tagagagata cagacatgga taaacaatac ctacacgaaa
    11881 agctggatgc catgcgccag aattttgttg aatcaaccca ccacgaacga tcggtgggcg
    11941 tgctagacca agcgcatatg agcaaaaaaa tgcttaaaat caagaaaaaa ttagttgctc
    12001 ttgaaatgga acggtgccag agaaaaattg agcacaaaga ctgttccaag attgaccaaa
    12061 aaatcaaaga acagaaggag atatttgaat cctgttgtaa aaaagattaa ggaggacgtg
    12121 cgtggaatta ctgatttacc tcatcctatt tttactggtt ttgattgtct caagtacaac
    12181 caataagctc ctgccctttt tgcctctccc tttggtgcag attcttttgg gaattgtgat
    12241 tggtctcttt ttacccaata ctgactttca ccttaatacg gagttgtttt tggcactggt
    12301 tatcggaccc ttgcttttcc gagaggctga agaagcagat gttacggcta ttttaaaaca
    12361 ctggcgaatc attgtttatc tcatatttcc agtgattttt atctcgacct tgagtttggg
    12421 tggcttggcc catcttcttt ggttcagcct tcccttggca gcttgcttgg ctgttggggc
    12481 agcccttggt cctacggact tggtggcctt tgcctctctt tcggagcgtt ttagctttcc
    12541 taagcgcgtg tccaatattc ttaagggcga aggactcttg aatgatgctt ctggtttggt
    12601 ggcttttcag gtagctttga cagcttggac aactggagct ttttctctgg ggcaagctag
    12661 cagttcgctc atcttttcaa tcctaggcgg ttttttaatt ggatttttaa cggccatgac
    12721 caaccgcttc ctccatacct tcttgctaag tgtgcgcgca acggatattg ccagtgaact
    12781 tttattagaa ttgagtttgc ctctagtgac cttctttctg gcagaagaag ttcatgtttc
    12841 aggtattatt gccgtcgtag ttgctggaat tttaaaggca agtcgcttca agaaaatcac
    12901 gctcctcgaa gcccaagtgg atacggtgac cgagacggtc tggcatacag tgacctttat
    12961 gctcaacggt tctgtctttg tgattttagg gatggagttg gaaatgatag cagaacctat
    13021 cttgaccaat ccaatctata atcctctact tttattgcta tctctcatcg cccttacctt
    13081 tgtcctcttt gtcattcgtt ttattatgat ctatggctat tatgcctata gaaaccgacg
    13141 cctcaagaaa aagctaaata agtatatgaa ggacatgttt ctcttgacct tttcaggtgt
    13201 taagggaacg gtgtcgattg ctacgattct cttgatacca agtaatctag aacaggagta
    13261 tcctcttttg cttttccttg ttgcaggtgt gacgcttgtc agctttttaa caggtctctt
    13321 ggtcttgcct catctttctg atgaagagga agaaagcaag gattatctca tgcatatcgc
    13381 cattttgaat gaagtaacgc tagagttgga aaaagagttg gaagacacca gaaataaact
    13441 tcccctctat gcggctattg acaattatca tggacgtatt gaaaatctca ttttaagcca
    13501 agaaaaccag gatgatcaag aagattgggc tgctttgaaa ctcttgattc ttagtattga
    13561 aagtgatggt ttggaacagg cctatgaaga ggggaacatt agcaatcgtg cttaccgagt
    13621 ttaccaacgt tatctgaaaa atatagaaca aggaatcaat cgtaaacttg cctcaagact
    13681 gacctattat ttccttgttt ctttgcggat tttacgtttt ctccttcatg aagtttttac
    13741 tctcggaaag accttccgta gctggaagaa caaggagcaa agccgtctcc gtgctcttga
    13801 ttatgaccaa attgcagagc tctatcttgc caatacggag atgattattg aaagtttgga
    13861 aaacctgaag ggagtctaca gacgctcttt gattagtttt atgcaggagt ctcgtcttcg
    13921 agaaacaact attatcagca gtggtgcctt tgtcgaacgg gttatcaatc gtgtcaaacc
    13981 caacaatatc aatgaaatgc tgagaggcta ttatctggag cgcaagttga ttttcgaata
    14041 cgaagaaaaa cgattaatta caactaagta tgccaagaaa ttacgacaaa atgtaaataa
    14101 cttagagaac tattccttga aggaagctgc caataccctg ccgtatgata tggtggaatt
    14161 ggtaagaaga aattagttaa tactcttcga aaatctcttc aaaccacgtc agcgtcgcct
    14221 tgccgtatgt atgtgactga cttcgtcagt cttatctaca acctcaaaac agtgttttga
    14281 gcagcttgcg gctagctttc tagtttgctc tttgattttc attgagtata agattataaa
    14341 tgaaggagta tgacatgaaa aagtggtgga aagagctgat agacaagcct ttattaaaag
    14401 cttttttgca ttattatcaa gcatcagata gtgagttgac cagtgtcgca gtagcctact
    14461 attggttgat ttcgattttc cccctgcttt tggtggtggt caatatcctc ccctattttc
    14521 agattcctgt gggagaattt ctgggcttta tgaaagacgt cctgccccca agcctctatg
    14581 aaggtgtgga aaaaatagcc agagaagtct tgacgcaacc ttcaacaggt ttattgagtt
    14641 tttctgtttt atcggcgtta tggagttttt caaaatctat gaatttcttg caaaaagctt
    14701 ttaacaaggc ttatggcgtc gaaaagagtc gtggacttat ttcccatcag atgctaagtc
    14761 tcctagtcag ttttggcttg cagctcctct ttgcgtttgc cttgtttttg attttatttg
    14821 gtcagatgat tttggcttta cttgctcatt attggacaaa agatggcatt atctatcagg
    14881 ctttacaagg gttggcaggt cctctgattt acgccctcct ctttgctatc ttggtcatgc
    14941 tttattattt tcttcccaat ctatctaaca ggaaaattag ctatacccta ccaggcagtg
    15001 cctttgttct cttagtgatt ttaggtttac taactctgtt ctctagttat ctcaattact
    15061 atgtccatca tttggtggat gtccgaattt taggttccgt tcttcttgtt gttatgatgt
    15121 tttggtttat cttgattgct aaaattgtta tcctaggcgc ggttatcaat gccagtatgc
    15181 agagtttgaa agatccggtc tttaaaaaag actaactatt tatccattac aaaagcgcat
    15241 agtatcaaga ctttatagaa ccttgatact atgcgctttt gtgctttgac agttttttgt
    15301 atagtttttg tccaagattt ctaaatcatc tgattaaatt cctattttcc cctatcattg
    15361 tccctgtttt ttcgaaaatg gaaggagtat aataaatcta tcaataaaat gataggagga
    15421 actttatggg tcatattttc ttttttctaa gtgtcttttt ggcagggatt ctatccttct
    15481 tttctccttg tatcttacct ttgttaccgg tctatacagg agtgttacta gatgataagg
    15541 atggtgctca ggcttctagc ggcaaatttt caatctcagt tactagttta ttacgaactc
    15601 tggtctttat agcaggaatt tcctttatat ttattttgtt gggctatgga gctggttttt
    15661 taggcgattt gctttatgct tcttggttcc aatatcttac tggggcaatt attatccttc
    15721 ttggtttgca ccaaatggag attctacact ttaaggggct ttataaggaa aagaggctac
    15781 aactgcaagg acaggggcaa aatggtaagg gctatagtca ggcattttta ttgggcttga
    15841 cctttagttt tgcttggacg ccttgcgtgg ggccggttct ggggtctgtt ttggccttgg
    15901 cggcttcagg tggttcagga gcttggcagg gagctggtct catgttggtg tatacgctgg
    15961 gcttggcgct accattcttg cttctagctc tgacctctag ttatgttttg aaacatttcc
    16021 gaaaacttca tccctatctc ggaatcctca aaaaagtggg tggttttctc attattgtga
    16081 tgggattctt ggttctgttt ggaaatgctt caattttaag tcaattattt gaataaaatg
    16141 gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc ttggagcagg ttcgctcctt
    16201 tgtttgacgg cttgttcagg caagtccgtg actagtgaac accaaacgaa agatgaaatg
    16261 aagacggagc agacagctag taaaacaagc gcagctaaag ggaaagaggt ggctgatttt
    16321 gaattgatgg gagtagatgg caagacctac cgtttatctg attacaaggg caagaaagtc
    16381 tatctcaaat tctgggcttc ttggtgttcc atctgtctgg ctagtcttcc agatacggat
    16441 gagattgcta aagaagctgg tgatgactat gtggtcttga cagtagtgtc accaggacat
    16501 aagggagagc aatctgaagc ggactttaag aattggtata agggattgga ttataaaaat
    16561 ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa cttatggtgt ccgttcttac
    16621 ccaacccaag cctttataga caaagaaggc aagctggtca aaacacatcc aggattcatg
    16681 gaaaaagatg caattttgca aactttgaag gaattagcct aggaggcgtc ttatgaatga
    16741 taagttaaaa atcttcttgt tgctaggagt attttttcta gccataaccg gtttctatgt
    16801 tctattgata cgaaatgcag ggcagacaga tgcctcgcaa attgaaaagg cggcagttag
    16861 ccaaggagga aaagcagtga aaaaaacaga aattagtaaa gacgcagact tgcacgaaat
    16921 ttatctagct ggaggttgtt tctggggagt ggaggaatat ttctcacgtg ttcccggggt
    16981 gacggatgcc gtttcaggct atgcaaatgg tagaggagaa acaaccaagt acgaattgat
    17041 taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat gatgccaagc aaatttctct
    17101 caaggaaatc ctgcttcact atttccgcat tatcaatcca accagcaaaa ataaacaagg
    17161 aaatgatgtg gggacccagt accgtactgg tgtttattac acagatgaca aggatttgga
    17221 agtgattaac caagtctttg atgaggtggc taagaaatac gatcaacctc tagcagttga
    17281 aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac catcaagact atctcaagaa
    17341 aaatccaaat ggctactgcc atatcaatgt taatcaggcg gcctatcctg tcattgatgc
    17401 cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag accctgtcac ctgaggagta
    17461 tgcagttacc caggaaaatc aaacagaacg agctttctca aaccgttact gggataaatt
    17521 tgaatccggt atctatgtgg atatagcaac tggggaacct ctcttttcat caaaagacaa
    17581 atttgagtct ggttgtggct ggcctagttt tacccaaccc atcagtccag atgttgtcac
    17641 ctacaaggaa gataagtcct acaatatgac gcgtatggaa gtgcggagcc gagtaggaga
    17701 ttctcacctt gggcatgtct ttacggatgg tccacaggac aagggcggct tacgttactg
    17761 tatcaatagc ctctctatcc gctttattcc caaagaccaa atggaagaaa aaggctacgc
    17821 ttatttacta gattatgttg attaatactc ttcgaaaatc tcttcaaacc acgtcagcgt
    17881 cgccttaccg tatgtagggt tactgacttc gtcagtttta tctacaacct caaagctata
    17941 ctttgagctg acttcgtcag ttttatttac aacctcaaag cggtactttg agaaacctgt
    18001 ggctatcttc ctagtttact ttttgatttt tattgagtat aagaggtctt tcctaagcag
    18061 ttagaggaga attttgctat actgatacta gtaagtggta aaggagcaga tcatgaccta
    18121 cacaatctta atcgtagaag atgaatatct ggtaagacaa ggtttgacta aactggtcaa
    18181 tgtagcagcc tacgatatgg aaatcatcgg tcaggctgaa aatggaaggc aggcttggga
    18241 attgatccaa aagcaggtgc cagatatcat tttaaccgat atcaacatgc ctcatctaaa
    18301 tggcatccag ttggccagtc tggtacgaga aacctatcct caggttcatt tggtcttttt
    18361 aacaggttac gatgattttg attatgcctt gtctgctgtc aaactaggtg tggacgacta
    18421 cctgctcaaa cccttttctc gtcaggatat tgaggaaatg ttggggaaaa tcaaacaaaa
    18481 actagacaag gaagagaaag aagagcagtt acaagattta ttgactaata ggtttgaagg
    18541 aaacatggcc cagaaaatcc agtctcatct ggctgatagc caatttagtt taaagtcttt
    18601 agccagtgac ttaggtttta gtccgaccta tctgagttcc ttgattaaga aagagttggg
    18661 cttgcctttt caggattatc tggtgagaga acgtgttaaa caagccaagc tcttgctttt
    18721 aactacagat ctgaagattt atgagatcgc agagaaggtt ggttttgaag atatgaacta
    18781 ttttacccaa cgttttaagc agattgcagg tgtgacacct cgtcagttta agaagggaga
    18841 agaccgatga agcgttcttc tcttttagtt agaatggtta tttccatctt tctggtcttt
    18901 ctcattctcc tagctctggt tggaactttc tactatcaat caagttcttc agccattgag
    18961 gccaccattg agggcaacag ccaaacgacc atcagccaga ctagccactt tattcagtct
    19021 tatatcaaaa aactagaaac cacctcgact ggtttgaccc agcagacgga tgttctggcc
    19081 tatgctgaga atcccagtca agacaaggtc gagggaatcc gagatttgtt tttgaccatc
    19141 ttgaagtcag ataaggactt gaaaactgtt gtgctggtga ccaaatctgg tcaggtcatt
    19201 tctacagatg acagtgtgca gatgaaaact tcctctgata tgatggctga ggattggtac
    19261 caaaaggcta ttcatcaggg agctatgcct gttttgactc cagctcgtaa atcagatagt
    19321 cagtgggtca tttctgtcac tcaagaactt gttgatgcaa agggagccaa tcttggtgtg
    19381 cttcgtttgg atatttctta tgaaactctg gaagcctatc tcaatcaact ccagttgggg
    19441 cagcagggct ttgccttcat tatcaatgaa aaccatgaat ttgtctacca tcctcaacac
    19501 acagtttata gttcgtctag caaaatggag gctatgaaac cctacatcga gacaggtcag
    19561 ggttatactc ctggtcacaa atcctacgtc agtcaagaga agattgcagg aactgattgg
    19621 acggtacttg gcgtgtcatc attggaaaag ttagaccagg ttcggagtca gctcttgtgg
    19681 accttgcttg gggccagtgt cacatctctt cttgtctgtc tctgcttagt gtggttcagt
    19741 cttaaacgct ggattgctcc tttgaaggat ttgagagaaa ccatgttgga aattgcttct
    19801 ggtgctcaaa atcttcgtgc caaggaagtt ggtgcctatg aactgagaga agtaactcgc
    19861 caatttaatg ccatgttgga tcagattgat cagttgatgg tagctattcg tagccaggaa
    19921 gaaacgaccc gtcagtacca acttcaagcc ctttcgagcc agattaatcc acatttcctc
    19981 tataacactt tggacaccat catctggatg gctgaatttc atgatagtca gcgagtggtg
    20041 caggtgacca agtccttggc aacctatttc cgcttggcgc tcaatcaagg taaggacttg
    20101 atttgtctct ctgacgaaat caatcatgtc cgccagtatc tctttatcca gaaacaacgc
    20161 tatggagata agctggaata cgaaattaat gaaaatgttg cctttgataa tttagtctta
    20221 cccaagctgg tcctacaacc ccttgtagaa aatgctcttt accatggcat taaggaaaag
    20281 gaaggtcagg gccatattaa actttctgtc cagaaacagg attcgggatt ggtcatccgt
    20341 attgaggatg atggcgttgg cttccaagat gctggtgata gtagtcaaag tcaactcaaa
    20401 cgtgggggag ttggtcttca aaatgtcgat caacggctca aacttcattt tggagccaat
    20461 taccagatga agattgattc tagaccccaa aaaggaacga aagttgaaat atatataaat
    20521 agaatagaaa ctagctaact cccagtcaat tctgggagtt ttatgcgtaa ttgggcagac
    20581 tttataggtt gtctatcttg ctaaaaacaa gaaaaaacgg tatgatagaa gagtgacaac
    20641 agaggtaaca gagatgaacg agacacagat tcaaagagaa acacgtcagg tagtggaaga
    20701 tgttttagaa aagaccaatt tgaagcaggg ggtccttttt gttttaggcc tatcttctag
    20761 tgaggtgcta ggtggtcaga ttgggaaaga atccagtcaa gagattggtg agctgatagt
    20821 ggagactatc ttgggtattc taggtagtag aggtatccat ttagcagttc aaggttgtga
    20881 gcatgtcaat cgggctctcg ttgttgaacg tcaggtggca gagcagtttg atctggaaat
    20941 tgtcagtgtc catcctactc ttcatgcagg aggttcgggg cagttggcag cctttaagtt
    21001 tatgcaggat ccagttgagg ttgaatttat caaggctcat gctggattgg atatcggaga
    21061 cactgcaatt ggcatgcatg tcaagcatgt tcaggttccg attcgcccta ttttgagaga
    21121 gattggtcat gcccatgtaa cggcactggc tagtcgtcca aaattaatcg gaggtgcgcg
    21181 tgcgcactat ccgcaagatg ctattagaaa gtcttgagaa tgaataaagg agatgaaagt
    21241 gtttaaaaaa gaccgttttt caattcgtaa gattaaggga gttgtaggct ctgtatttct
    21301 tggaagcctt ttgatggctc cttctgtagt ggacgcagct acctatcact atgtaaataa
    21361 agagattatt tcacaagaag ctaaagattt aattcagaca ggaaagcctg acaggaatga
    21421 agttgtatat ggtttggtgt atcaaaaaga tcagttgcct caaacaggga cagaagcatc
    21481 tgttttgaca gcttttggtt tgctgactgt tgggagcttg cttttaatct acaagagaaa
    21541 gaaaattgct agcgtctttc tagttggagc tatgggattg gtagttcttc ctagtgcagg
    21601 ggctgtagac ccagttgcga ccctagcgct ggctagtcga gagggtgttg ttgaaatgga
    21661 tggctatcgc tatgttggtt atctatcagg tgacatcctc aaaacgcttg gcttggacac
    21721 tgttttagaa gaaacctcag caaaacctgg agaggtgact gtagtcgaag ttgagactcc
    21781 tcaatcaaca acaaatcagg agcaagctag gacagaaaac caagtagtag agacagagga
    21841 agctccaaaa gaagaagcac ctagaacaga agaaagtcca aaggaagaac caaaatcgga
    21901 ggtaaaacct actgacgaca cccttcctaa agtagaagag gggaaagaag attcagcaga
    21961 accagctcca gttgaagaag taggtggaga agttgagtca aaaccagagg aaaaagtagc
    22021 agttaagcca gaaagtcaac catcagacaa accagctgag gaatcaaaag ttgaaccacc
    22081 agtagaacaa gcaaaagtcc cagaacaacc cgtgcaacct acacaagctg agcaaccaag
    22141 tacaccaaaa gaatcatcac aacaagaaaa tcctaaagaa gataggggag cggaagagac
    22201 accgaaacaa gaagatgaac agccagcaga agccccagaa atcaaggttg aagaaccagt
    22261 agaatcaaaa gaggagacta aaacagctaa ggggacgcaa gaagaaggca aagaaggtca
    22321 agcaccagta caagaagtaa acccagaata taaagtaaca acaggtacag ttgagaagtc
    22381 taccgaaagt gaattagatt tcacaacaga agtagttccg gatgacacaa aatatgtaga
    22441 tgaagaagtt gttgaacgtc aagggtctaa aggagttcaa gttacgaaaa caacttacga
    22501 aacagtggaa gttgtagaga cagacaaagt cctttctaca actacagaag tgaaaactcc
    22561 tgttgttcct aaagtcgtta aaaaaggaac aaaaccagtt gaaggaacag cagttgaaac
    22621 aagagaagaa gtcattcctt ttgctacaaa agaacaagaa gatggcactt taaaacgcgg
    22681 aacaagacaa gtagctcaag aaggtgtaaa cggtaagaaa caaattactg aaacctataa
    22741 aacaattcgc gcagaaaaaa caaacgaagc tccaacagta gaagaaacag ttctccaagc
    22801 acctcaagat gagattatca aaaaaggcac aaaaggttta gaaaaaccaa ccttagaatg
    22861 ggttaaaaca gataaagatg tcttgaagaa gagtgcgaca gccagttata cattgaataa
    22921 accagatggg gtagaaatca aatccatcaa agtagctcta aaagataata ctggaacagt
    22981 tattaaagaa gtaacggtag aagaaaataa cttaaacgtt actttagaca acttgaaata
    23041 ttatcaaggt tatacactat ccacaaccat ggtctataat cgaggcgaag gcgaagaaac
    23101 tgaaacgtta gaagataaag aagttcagtt agaccttaaa aaagttgaaa tcaaaaacat
    23161 caaagaaact agcttgatga gtgtggatga tgctggtgtt gaaacagata agagcttact
    23221 tactgaaaaa ccgacagacg ttgctccact ttacctacga gtgacaactc atgataacaa
    23281 agtaacaaga cttgctgttg ataagattga agaagtagaa gaagacggaa aaactttata
    23341 caaagttact gccaaagcac cagacttagt tcaacgtaat gctgataaca cacttagcga
    23401 agagtatgtt cattactttg aaaaacaact tccaaaaatt ggaaatgtgt attacaactt
    23461 caacgagttg attacagata tgcaaaaaac accgaatggc gagtttaaac ttggtgcaga
    23521 cttgaatgct gtcaatgttc caacaccaaa taaatcttat gtgactgcta aatttactgg
    23581 taagttgtat agtgaaggtg ataaacacta tactattcac aacttagcac gtccattgtt
    23641 tgcgcaagct gaaaacgctc atattcatga catcaacctc ggtaatgtaa atattaatat
    23701 gccgtgggcg aacaaaacag cacctcttgg tgaaatgttc aagaagtcaa ctattgaaaa
    23761 cgtcaaagta acaggtaatg ttgtcggtaa caatgacgtt acaggtatgg tcaacaaact
    23821 ggacgaatct gatatgcgta acgtagcttt cattggaaat attacaagtg taggtagcgc
    23881 tggatggtgg tctggtggac ttgtcagtga aagctggaga agtaacacag ataattctta
    23941 tattgatacc accatcaaag gtaataaagc taaggtaggt ggattaattg ctaagttaaa
    24001 tcacggtgct gacccacgag atgttggtgc gagaggtcgt ttgaagaact ctgtcgcaaa
    24061 aggtactatt gatgtgagag acccacaaga aactggtgga ttgctgcatt ctaactggtc
    24121 atggggtctt gcagaaaaca atattaccat gatgaaagtg aagaatggag gagaaatttt
    24181 atatggttct cgtgatgcag aagatgatga ttacttcgga gcgaattggg tgcgtaataa
    24241 taatgcgttc gtcaatggaa tcagtgaagg gaaacaatcc tattctcgtt ctagtcgctg
    24301 gaaagggatt tctgaagatg aagctaaaac tcgtattgcc aaaatgggaa ttacagctca
    24361 tgaatacgaa attacacaac atttgactga taaattgaac cgtgcagcat ttaaagaaga
    24421 cacatataaa acaactcaag attacaaaac tgaaagagaa ttagcgtatc gtaatattga
    24481 aaagcttcaa ccattctaca ataaagaatg gattatcaac caaggtaaca aattaacaga
    24541 cggttcaaac ttaatgatta aagaggtatt gtccgttata ggtatgaaga acggtcagtt
    24601 cgtgaccgat ttgtctgata ttgataagat tatgattcac tacgctgatg gtacgaaaga
    24661 agaaaaaact gtcacacgta aagctgactc aaaagtgcaa caaattcgtg aatatagtgt
    24721 tgaaggtctt ggtgatgttg tgtacacacc aaatatggtc gaaaaagata gagcgcaatt
    24781 aattactgat attaaggcga aattggatag cgtccaattg atttcaccag aagtgcgcaa
    24841 tttgatggat aaacgtggca aagcgcatga aaacacggat gaacgtcgta atggctacat
    24901 tcgaaaccta ttccttgaag aaagtttgga tgaagtgaaa ggaaaccttg ataagcttgt
    24961 gaaagctctt gttgaaaatg aagaccatca attgaatggt gatgaagcgg caatgaaagc
    25021 tcttgtcaag aaagttgaag acaacaaagc gaaaatcatg ttaggtcttg cttatctcaa
    25081 tcgctactat ggattcaaat atgacgaaaa gtctatgaag gatattatga tgttcaaacc
    25141 ggacttctat ggtaagaatg ttagtgtctt ggacttcttg attagagttg gttcaagaga
    25201 acacaatatt aaaggtaaca gaacgttaga agcttatcgt gaagtaattg gtggaacgat
    25261 tggtatcggt gagttaaacg gtttcttaaa ctataatatg cgtttattca cagaagaaac
    25321 tgacatcaat acttggtaca aaaaagctgt atcgcatacc aactatattg ttgaaaaaca
    25381 atcctcaaac cctgcgtttg ccaacaagaa atatcgcctt tatgaaaact tgaacaatgg
    25441 tgaacatggt aaatatattt taccacttct cactacgaag aaagctcata tgttcttgat
    25501 ttcaacctat aatacattag cgtttagtgc gtttgagaaa tatggtaaga atacagaagc
    25561 tgaacgtgaa gcgtttaaga aagaaatcga tttacgtgct caagagcaaa ttaattactt
    25621 agacttctgg tcaagacttg cagctgataa tgtacgtgac agattgttaa aatctgaaaa
    25681 tatggttccg tctgcaattt gggataacca agaagttcca ggtcatggat gggctgatag
    25741 aatgggtcat aataagaatg gtgactatgc tccggttcgt gagttctatg gacctacagg
    25801 taaatggcat ggatacaatg gtacgggtgc atatgcttat atctttacta atccacaaaa
    25861 ctcagaagct gtatattata tcatatctag tatgatcagt gatttcggta cttctgcatt
    25921 cactcatgaa actacacaca ttaatgaccg tatggcgtat ctaggtggat ggcgtcaccg
    25981 tgaaggtact gacgtagaag catttgccca aggtatgtta caatcaccgg ctgtctcaag
    26041 tccgaacggc gactacggtg ctttaggtct taacatggct tacaaacgtg aaaacgatgg
    26101 taaccaatgg tacaactatg attcaaataa attagatagt cgtgcgaaga ttgaccatta
    26161 catgaagaat tacaacgaag cgctcatgat gcttgaccac ttagaagctg atgccgttat
    26221 cgcgaagaat aacggagata acaacaagtg gttcaagaag atggataaga aatggcgtga
    26281 gaacgctaat cgaaatggat tagtgggaca accacaccaa tgggatttac ttcgtgacct
    26341 aaatgaagaa gagaataaga agaaattgac aagcattgat gaccttgtag atggaaatta
    26401 tgtaacgaag cataatatgc cgggtaataa acactatcgt gctgaagggt ttgatacagc
    26461 gtatcaaact gtaaacatga tggctggtat ttacggtggt aatactagta agagtgctgt
    26521 tggttctatc tcgttcaaac ataacacctt ccgtatgtgg ggttacttcg gttatcttga
    26581 tggatttgta ggttatgcat ctaacaaata taaagacgcg gctaacaaag aaaataaagg
    26641 cttacttggc gacgacttta ttatcaagaa agtgtctgac ggtaaatttg acagcctaga
    26701 agcttggaag aaagaatggt ttaaagaagt taaagctaaa ggtgaaaaag gatttgttgc
    26761 tattgaaatt gatggtaaaa caatcactaa ctatgctgaa cttcgtgaat tgttcgacaa
    26821 agctgttgaa gctgacctga aagctggtaa ctctaaccaa acagttgccc ttaaagaaaa
    26881 ggtttataaa caactcttgc agaaatcaga tggatttgta ggaaatcttt ttaaagcata
    26941 gattgtatta aatagatgag taaaaaaggt agattaagtt tttcttgatc tgccttttta
    27001 tgctatactt aaggtatgca tagaaaaaca gtgattgatt ttaggacttt gggggagaga
    27061 tataccttta cccagcctat taaagagttg aaaacgagaa atgtagaaga agtggcagat
    27121 ttgctggcac aagtggaaag ctaccaagag caaggttatt atgtggtggg gtatgtcagc
    27181 tacgaggctg cacctgcttt tgaggagaaa ttagcagttc acaaggttcc tctactgggc
    27241 gagtacttgc tttactttac tgttcacgat agggtagaga cctcccctat tcctctgact
    27301 tatgaggata ttgatttgcc ctcaaattgg caggaagtga cgtctgcagc agactatgaa
    27361 aaggccattg cccagataca ccatcacttg aggcagggag acacctatca ggtcaactac
    27421 accgtccaac tcaagcaaaa gttaagtgcc aatccttttg ccatctacaa tcgtatggtg
    27481 gtagagcagg aggcgggcta caatgcctat gtggaacatg acgagatggc agtgatttcc
    27541 atgagcccag agctcttttt tgagcaaaat gatcgcgagt tgacaacacg accaatgaag
    27601 gggacgactc agcgtggggt aactgaccaa gaagatcttg aacaggccag ttggttggaa
    27661 caggatccca aaaatcgctc tgaaaatatg atgattgtgg acctcttgcg caatgatatg
    27721 aaccgtattt ctgaagttgg gagcgagcac gtggagcgtc tgtgtcaggt agagcagtat
    27781 tcaactgttt ggcagatgac ttcgaccatc aagagtcagt tgcgagagga tgtggacctt
    27841 gttgaaatct tccgctcact ctttccttgt ggttccataa cgggtgcacc gaaaattgcg
    27901 acaatggaga ttatcaagga cttggagcct caaccgcgtg gagtctactg tggaacgatt
    27961 ggtctcttgc ttccaaatgg acgacggatt tttaatgtgg ccattcgtac cattcaactt
    28021 cacaaaggtc aagccattta tggagttggc ggagggatta cttgggatag cacatgggaa
    28081 tctgaatacc gagaggttca tcaaaaggca gcagttcttt atcgtaaaca agctcgcttc
    28141 caactgatta cgacagggga aatcagccag aagaacctgc tgtttgaaga tcaacatctg
    28201 gaaagactga gaaaagctag tcgttatttt gcttttcctt ttgatgcaga agacttggga
    28261 cacaagattg aggaagagtg tcaggattgt gaagctaatc gagattaccg cttgcgaatc
    28321 agccttagca aatctggaga gatagaagtc aatcgtcaag tattaacccc tctcagtaca
    28381 agcttttgtc aggcccaagt ctgtcttcag gaagctgctt tgaatcaatc ctttacctac
    28441 tttaaaacca ctcaccgacc gcatttgagc ctaggagaac aagagaagat ttaccacaat
    28501 aagtcaggag aactgcttga aacctctata ggaaatttgg ttctgaaaat cgctggaaaa
    28561 ctctacacac cgcctatccg acttggaatc ttgccaggaa tttaccgtca gcatttgcta
    28621 gaaacaggac aggtagaaga gaaagtcttg accttggcag atttaaccca agcagaagct
    28681 atttacggct gtaatgcagt gagaggcttg tatgaactaa gccttgagga gaactagatg
    28741 aaattgatat ttttgcatgg gttagggcag tcagcagagt cttggaaaga agttcggaat
    28801 ctactgacag attatccttc tgaggctatc gagttatttc cttctggagt tagtaactat
    28861 caacaagcta aagagcgagt ttatcagcac ctagctcaag agacagaacc ttttgttttg
    28921 attggattgt ccttaggtgc tgccctgaca ctagaacttt ccagttacga tttaccaaat
    28981 cttcgagctt tgattctgtc aggatgcccg cttaaattag cagggaatat cctattttat
    29041 cttcaattgc tgatttttaa actacttccc aaaagagtat ttgaaaaaca gggagcagac
    29101 aagactctta tggtcggagt ttctgaggaa ttgaagacac ttgatttaac ggatatagca
    29161 gggacttgct cctatccaac cttactaatt tgtggcagca aagataaacc gaatcttagt
    29221 tctatgaaag ctctccatag actgttaaca gattcgcagt ttcagatcat tcctgatggc
    29281 cctcatgtct tgaataaggc aaaaccaaag gagtttgtag aaaagaccag aagtttcctt
    29341 gaattgctga aataagtttg ataaaataat attgaaatcg atatcataat tatgggagaa
    29401 agaaatgaat aaacgtctat ttttaaaaat gagtctggtg acgttgccaa ttttagcctt
    29461 gttttcacaa ccagttttgg cggaagaaaa catccatttt tcgagctgta aggaagcttg
    29521 ggcgaatggc tattcggata ttcacgaggg ggaacctggt tattctgcca agttagaccg
    29581 tgatcatgat ggtgtggctt gcgaattgaa aaatgctcct aagggtgctt ttaaagcaaa
    29641 acagtcaacg gctattcaaa tcaacacaag ttcagcaaca acaagtggtt gggttaagca
    29701 ggacggcgct tggtactact ttgatggaaa tggaaatcta gtgaaaaatg catggcaggg
    29761 aagctattac ctgaaagctg atggtaaaat ggcacagagt gaatggattt atgactcttc
    29821 ttatcaagct tggtattatt tgaaatcaga tggttcttat gcaaaaaatg catggcaagg
    29881 agcttattac cttaaatcaa acggtaaaat ggcacaaggt gagtgggttt atgattcttc
    29941 ttaccaagca tggtattact tgaaatcaga tggttcatat gctcgcaatg catggcaagg
    30001 aaactactat ttgaaatcag atggtaaaat ggctaaaggt gaatgggttt atgatgccac
    30061 ctatcaagct tggtattatt tgacatcaga tggttcttat gcttacagta catggcaagg
    30121 aaattactat ctaaaatcgg atggtaaaat ggctgtcaat gaatgggttg atggtggacg
    30181 ttattatgtt ggcgctgacg gagtttggaa ggaaggtcaa gcaagtacag cttcttctag
    30241 taatgatagc aatagtgaat attctgctgc tttaggaaag gcaaaaagtt ataattcgtt
    30301 attccacatg tcaaaaaaaa cgtatgtata gacaattaac ttctgatttt gataaatttt
    30361 caaatgatgc agctcaatat gccattgatc attagatgat taacagatac tggtaggcga
    30421 aaaaattcct tataattcac ttacgcaaac ctttgcataa gtgaatggat tttgatatac
    30481 tagtactgta agcattttca attactacac aatgaaaaag gagaatatga tgagtcaaaa
    30541 gattattggg attgaccttg gtggaacttc tatcaaattt gcaatcttaa caacagcagg
    30601 agaaatccaa ggaaaatggt caatcaagac caacattttg gatgagggaa gtcatatcgt
    30661 tgatgatatg attgagtcta ttcaacatcg tttggacttg cttggattgg cagcagcgga
    30721 cttccaaggc attggaatgg gatcaccagg tgtggttgac cgtgacaaag ggactgttat
    30781 cggtgcctac aacttgaact ggaaaaccct tcaaccaatc aaacaaaaga ttgaaaaagc
    30841 cttgggcatt ccatttttca tcgataatga tgccaacgta gcagctcttg gtgagcgctg
    30901 gatgggtgct ggagataacc aaccagacgt tgtctttatg acactcggta ctggtgttgg
    30961 tggtggtatt gtcgcagaag gcaaattgct tcatggtgtt gctggtgcag caggtgaact
    31021 tggtcatatc actgttgatt ttgaccaacc aattgcatgt acttgtggta aaaaaggctg
    31081 ccttgagaca gttgcttcag caacaggaat tgtcaacttg actcgtcgct atgccgatga
    31141 atacgaaggc gatgcagcct tgaaacgctt gattgataac ggagaagaag taactgctaa
    31201 gactgtcttt gatctcgcaa aagaaggaga cgaccttgct ttgattgttt accgtaactt
    31261 ctcacgttac ttgggaatcg cttgtgctaa cattggttca atcctaaacc catcaacaat
    31321 cgtcatcggt ggtggtgtgt cagctgcggg agaattcctt ctacaaggtg ttcaaaaagt
    31381 ctatgatgaa aatactttcc cacaagtacg cacatctact aaattagctc ttgcaactct
    31441 aggaaatgac gctggagtta tcggagcagc atcacttgta ttgcaataag ataatgagag
    31501 aggaaaaatg ctaacctaga gttagtaatg ttcctctttt attttttatg ctatactagt
    31561 taggacaatg aatgaggtga gagtaaatga caaaagcaga tacgattttt aaagagaata
    31621 ttgaacgcat tctaaaggaa ggtgttttct cagagcaggc tcgtcctaag tacaaggatg
    31681 ggactgttgc taattccaag tatgtaactg gtgccttttc cgagtacgac ttatctaaag
    31741 gagaatttcc tatcacaacc ttgcgtccca ttgcaatcaa atccgccatc aaagaagttc
    31801 tctggattta ccaagaccag tcaaatagct tagaagtgct taatgacaag tacaatgttc
    31861 actactggaa tgactgggaa gttggagaca cgggaaccat tggtgagcgc tatggtgccg
    31921 ttgttaagaa acacgacatt atcaataagc ttctcaaaca gttggaaacc aatccttgga
    31981 atcgccgcaa tattatttcg ctctgggatt accaagcttt cgaagaaaca gatgggctgc
    32041 tcccgtgcgc ctttcagacc atgtttgatg tccggcgtgt tgatggggaa atctatctgg
    32101 atgcgacctt gacccagcgc tccaatgata tgctggtggc ccaccacatc aacgctatgc
    32161 agtatgtggc tttacagatg atgattgcca aacattttgg ttggaaggtt gggaagttct
    32221 tctatttcat caacaacctc catatctatg ataatcaatt tgaacaagct caggaattgc
    32281 tccgtcggga gccgtcaaac tgccaaccac gcttggtttt aaatgttcct gatgggacta
    32341 atttctttga tatcaaagca gaagattttg agttggtgga ttatgaccct gttaagccac
    32401 agttgaagtt tgacctagct atttaaaaga atagaaaaaa gaagttgaga ataatcccaa
    32461 cttcttttgt ttcttaacgt gatacgcggc gacgagctgc ttttttacga ttttcttcga
    32521 tgaaagctgc tttttgctct tctggttcga ttactttctt tttaaatgcg tatactgcac
    32581 ctgcaacggc agcgacagtt cctgcgacac ctgttacaag acctttagcg aatcctttag
    32641 ccatgagtct tcctccttta tattctcaat cagccagcct cctcaagagg tcacattttt
    32701 ctgactgacc tttttgtgtt ataataatag taacgaaaaa atgggaattt ttcaaggaaa
    32761 aaagatgaaa acaaaaataa ttgtgattgt tggaccgact gctgttggaa agacggctct
    32821 agctattgaa gttgcaaagc gctttaatgg cgaagtggtt agtggagata gccagcaagt
    32881 ctatcgagga cttgatattg ggacggccaa ggctagtcca gaagagcagg cagctgttcc
    32941 tcatcattta atcgatgtta gagagataac cgagtcttac tcggcttttg attttgtttc
    33001 agaagctaag atgactattg aggatattca gagccgtggc aagctagcca ttatcgccgg
    33061 tgggactgga ctttatatcc agagcttgct agaaggttac cacctaggtg gggagactcc
    33121 ttatgaggag attttagctt atcgagctag tttggagcca tattcagatg aggaattagc
    33181 ccatttggtg gagcaagcag gccttgagat tccccagttt aatcgtcgtc gtgctatgcg
    33241 tgccttagaa attgcccatt ttggtcagga tttggaaaat caagagatct tgtatgaacc
    33301 gctgattatc tgcttggatg atgaacgtag tcaactttat gagcgtatca accaccgagt
    33361 ggatttgatg tttgaggctg ggcttttgga tgaggccaag tggctgtttg accattcccc
    33421 taatgtacag gctgctaaag gaattggcta taaggaactc tttccttatt tccgtggaga
    33481 gcagaccttt gaggaagctc gtgagagtct taaacaggcg acccgtcgtt ttgccaagcg
    33541 tcagctgacc tggttccgta atcgcatgca ggtcaccttt tatcagattg gagaatctgg
    33601 tgtacaagac cgcattttaa gccagataga ggagttttta gatgattgaa acggagaaaa
    33661 aagaggagcg agtcctgctg attggtgtgg aattgcaggg tatggacagt tttgacctct
    33721 ccatggaaga attggctagt ttagcgaaaa cggcaggggc agtcgttgta gatagctaca
    33781 gacaaaaacg tgaaaaatat gattccaaga ccttcgtcgg ctctggtaag ttggaagaga
    33841 ttgcgcttat ggtggatgca gaagaaatca ctactgtcat cgtcaacaac cgtctgaccc
    33901 caaggcagaa tgtcaatcta gaggaagttc tcggtgttaa ggtcattgac cgtatgcagt
    33961 tgattttgga tatctttgcc atgcgggctc gaagccatga agggaagctc caagtccacc
    34021 tagcccaact caaatacctc ttgcctcgct tggttggtca ggggattatg ctcagccgtc
    34081 aggcaggggg aattggttcc cgtggtcctg gtgaaagcca gctggagctg aaccgtcgta
    34141 gcgttcgcaa tcaaatcacg gatatcgagc gccagctcaa ggtggttgag aaaaatcggg
    34201 cgactgtcag agaaaaacgt ttggagtcta gcacctttaa gattggtttg attggttata
    34261 ccaatgctgg gaaatcaact atcatgaaca tcttgaccag taagacccag tatgaagcag
    34321 atgagctctt tgcgactctg gatgcgacaa ccaagagtat tcatctggga ggcaatctcc
    34381 aagtaacttt gacagatacc gttggcttta ttcaagattt gccgacagag ttggtgtcca
    34441 gtttcaagtc aaccttggaa gaaagcaagc atgtggacct tctggttcat gttatcgatg
    34501 ctagcaatcc ttaccacgag gagcatgaaa aaacggttct ctccatcatg aaagacctgg
    34561 acatggaaga tattcctcac ttgacgcttt ataataaagc ggatttggtg gaggatttca
    34621 cgcctaccca aacgccatat accctcattt ctgccaagtc tgaggacagt cgtgaaaact
    34681 tgcaagcatt attgctagat aagattaagg aaatttttga agcatttacc ctgcgagtgc
    34741 ctttttcaaa gtcctacaag attcatgatt tagagagtgt tgcaattctg gaagaacgtg
    34801 attatcagga agacggcgaa gtgattacag gctacatttc cgagaaaaat aaatggaggt
    34861 tagaagaatt ttatgactga tattaaaact ttggctctaa agtatggagg ttatacaagt
    34921 ctggacaagg tctatctgga tcagcttcta gctggtaaaa cagagcagga gcagttaaca
    34981 cttattacac ctccgccaag tgttgttaat gcctactttg cagaactcta tcagaaaaaa
    35041 agtcctcagg ctgcgacgga ttattttgca gaactcagtc aggaactgaa tctttacaat
    35101 actgagccaa gtttcaccct agaaaataag ccttttattc ggcttaatct gtctggtaaa
    35161 tcctttggtt tttgttatga gagtgacggc tttggtcgga ttttctctga aaatgaggag
    35221 aaaatctcgg atgacttgct ctttgaaatt gcgcaaattt tctcccatca attagtcttt
    35281 gaagagtctg gtaagattta catgaagcct gtcaaggacg aggaagttgt cagcctagaa
    35341 agtctcacag ctttgactga tttggaaaga ttggctgatg gtcgaaaacg tctcaaaggc
    35401 tacagccaag aggatttatt gcaagaagct gctgcttttt ctggcaaacg ctatttccga
    35461 tcggaaaacc gcacagccat gttatatatt gattaattag aaagtatcga atggatattc
    35521 aatttttagg aacgggggct ggtcagccct ctaaagcccg caacgtttca agtctcgccc
    35581 tgaaactttt ggacgagatt aacgaagttt ggctctttga ctgtggagaa ggtacgcaaa
    35641 atcgcattct ggaaaccaca attcgaccac gtaaggtcag caaaatcttt attacccatc
    35701 tgcatggaga ccacattttt ggtttgccag gtttcctttc tagccgtgcc tttcaggcca
    35761 atgaagagca gacagatttg gaaatctacg gacctcaagg aatcaagtca tttgtcttaa
    35821 ccagccttcg tgtgtcaggt tctcgtctgc cctaccgcat tcatttccat gagtttgacc
    35881 aagattctct gggtaaaatt cttgaaaccg ataaattcac tgtgtatgca gaggagctgg
    35941 accacactat tttctgtgtt ggctatcgtg tcatgcaaaa ggatctagaa gggacgctgg
    36001 atgctgaaaa actcaaggct gctggtgttc cgttcggccc gctttttggt aaaatcaaaa
    36061 acggccagga tcttgttttg gaagacggaa ctgaaatcaa ggcagcagac tatatctcag
    36121 cgccacgtcc aggtaagatt atcactattt taggagacac tcgaaaaacg gatgccagtg
    36181 tgcgtctggc tgtcaatgca gatgtcctag ttcatgagtc cacttatggc aagggtgatg
    36241 aaaaaattgc tcgtaaccat ggtcactcaa ctaatatgca agctgcacaa gtagcggtag
    36301 aagcaggtgc caaacgcctc ctactcaacc atatcagtgc ccgtttcctc tcaaaagata
    36361 taagcaaact caagaaggac gctgccacaa tttttgaaaa tgtccatgtg gtcaaagact
    36421 tggaagaagt ggaaatctag cagtcacaga aaggataagt atgcctacta ttctcattac
    36481 cggagctagc ggtggtctag ctcaagaaat ggtcaaactc ctgcccaatg accaactcat
    36541 cttgcttggt agaaataagg aaaaattagc ccaactctac ggaaattatt cccatgcaga
    36601 attgattgaa attgatatta ccgacgattc agccctagaa gctctggtaa ctgatcttta
    36661 tctccgctat ggcaagattg atgtcttgat taacaacgct ggttacggga tttttgaggg
    36721 atttgaccag attgctgata aagatattca ccagatgttt gaggtcaata cctttgccct
    36781 gatgaatctg tctcgtcacc ttgcggctcg tatgaaggaa agcagcaaag ggcatatcat
    36841 caacatcgtc agcatggcag gtctaatagc tactggcaag tctagtcttt actcagcgac
    36901 caagtttgcg gctattggtt tttcaaatgc tctgcgactc gaacttatgc cctatggagt
    36961 ctatgtgaca acagtcaatc caggtccaat ccgaacagga ttttttgacc aagctgaccc
    37021 agatggaact tatcttaaat cggttgaccg cttcctctta gaggcagatg cagtggctaa
    37081 aaagattgtc aagattatag gcaaaaataa acgagaactc aatctcccga ttttgttgaa
    37141 cctagcccat aagttttata ctctctttcc caagctagct gataagttgg caggggaaac
    37201 ttttaattat aagtaaaaag aaccaatgtg caggttgttg ctagcctaca tattggttct
    37261 tatcatttct caactatcaa actgaacttc ttctagtaga tagtcgataa agcgttcgcc
    37321 catcttagat aggctggttt tctcatgctg gatatagacc agctcaatcg ggtcatcaat
    37381 atccagtggg atagaaacga tattgtctcc gtttaggttg ctgttcaaaa tccctgtcgc
    37441 aatggtataa ccatccaaac caatcaagag attaaagagg gtggcacggt cactgaccac
    37501 aatggatttc ttgtggtgtt cctgagaaag aatctcttct gaaaagtaga aggagttgtg
    37561 cgtcccttgg tcatagctga ggtaagggaa attctccaaa tcagacagtt tcaccttgtc
    37621 tttctttgcc agagggttgg tcttgctgac aaagatatgc ggttgcgctg tgaagagatg
    37681 gtgggctagc aggtgattgt catccagcat cttggttaaa acatcacggt tgtaactgtt
    37741 taagaagagg accccgacct cactgcggaa gttcttgacg tcgtcgataa tctcccaagt
    37801 ccgagtttca cgaaggaaga gttcgtattt ctccatatcg cttttcttga gcaaagagac
    37861 aaaggcattg accacaaagg catagtgttg agacgaaacg ctaaagagtt cgcggtgggc
    37921 gacaggattt ttatagcgtt cctccagaag ctgggtctgc tcgacaacct gacgggcata
    37981 agagagaaac tccatcccat cacgggtcaa ggtgattccc ttgggattgc ggataaagat
    38041 ctcaatgccc atttcatttt ccaaatctcg cactgcattg gagagacttg gctgagtgat
    38101 aaagagttgc ttggctgcct cattcatgga gccagtttcg acgattttga taatataatg
    38161 taattgttga attctcatgt ttttattgta ccatacttgc cttagaatcg ctaaagaaga
    38221 taggaaaata aggagcattg tatgagtctc ttcttgaaaa aaacacaaaa ttttgctaga
    38281 atgagtctta tgaaaacatt ctatgatgtg cagcaattcc tcaaacgatt tggtattatt
    38341 gtttacatgg gaaaacgctt atatgatatt gaactgatga agttggaact atctcggatt
    38401 tacgatgcag ggttgatgga taaattagac tatctagagg cagaagcagt tcttcgcaga
    38461 gagcacaagg tagaattgga ttatattgag aaaaatggag aaaagaacta atggttactt
    38521 ggattttgtg ggcacttata ctagcaatgt tggcgtggat gggctttaac tatcttcgta
    38581 ttcgccgtgc ggctaaaatt gtggacaata aggagtttga agccttgatt cgtacgggtc
    38641 aattgattga tttgcgcgac ccagcagaat tccacagaaa acatatcctt ggtgcacgca
    38701 atattccttc aagtcagttg aaaactagtc ttgcagcact tcgtaaagat aaacctgtcc
    38761 ttctctacga aaaccaacgt gcgcaacgag ttacaaatgc agctctttac ttgaaaaaac
    38821 aaggtttttc tgagatttat atcctttctt atggcttgga ttcttggaaa gggaaagtga
    38881 agactagcta accttatttc caaattagtc gaatgatagg atgaagctat tgttttatag
    38941 tataattaat ttgtataaaa tttaaagagt tcttagaaca tgaaagaaaa gaagaaaaat
    39001 ccactttttg tgggtatctt gtcgattatt cttggtttgt tatttccaat tgtaggcctg
    39061 attttgggta tcataggatt ggtcttggct atttcatacc aaaaagagtc acaattagac
    39121 tataaaatag aaaagattct taatatctta ggaattgtga tttctgtagt taactggatt
    39181 gtagcaatcg ccttaatttt tcggtaaata aaagaaaaaa gctttagttt taaagctttt
    39241 tttattttat cgactcatct ctaaatagtt tttaatgatt tgtaactctt tttggttcaa
    39301 agggcggtag ttaccttctg ctaaatctgg gttcaatgtg aagtccccaa attggattct
    39361 cttgaggcta gtcaccttaa caccaaccga gaggaacatt ttcttgattt gatgaaattt
    39421 tccttctgaa atggtgatag aggcttgact gagggaagga cttgctgata gaatctctag
    39481 tcttgcaggt ttacagatag tgccatctaa aaagacaatt cctttttgaa aggtttggat
    39541 atggtcaggt gttagaagtc cattaacctc aacttgataa gtcttatcga catgatattg
    39601 gggatggagg agttggaagc ccaagggacc gttatcggtc aagagaagga gtcctgttgt
    39661 atctcggtcc agtcggccga cggcatagag cttgtcagac tggatgtcag atggaagcaa
    39721 gtccatgacg gtcggaagtt ccttgtcttt gttggctgta acgacaccag caggtttatg
    39781 aagcataaga taggtgtgtt catagccttg aatgattcga tcctgaaaaa ggagttcttg
    39841 tagtcctgta tcgatatttt gagctaggga gcgggctggg caaccatcga ctagaatgtc
    39901 ccctttgagt aaggcttgtt tcatggcctt tcggctgatt ttttcttgag ctaataaatt
    39961 atctaaacgc atactgtgcc tatcttatca taagtcgctt gctttgaaaa ggcttgacgt
    40021 gaaaagaaaa gtggagtgaa aacatttaca cttgcttgag ttatgttatt tacttgaaat
    40081 tatggtataa tcgttcagtt agaaaataaa ttttgaatat tatagaggaa atcatgacaa
    40141 aattaagaga agatatccgt aacattgcga ttatcgccca cgttgaccac ggtaaaacaa
    40201 ccctggttga cgaattattg aaacaatcag aaacgcttga tgcacgtact gaattggcag
    40261 agcgtgctat ggactcaaac gatatcgaaa aagagcgtgg aattaccatc cttgctaaaa
    40321 atactgccgt tgcttacaac ggaactcgta tcaacattat ggacacacca ggacacgcgg
    40381 acttcggtgg agaagttgag cgtatcatga aaatggttga cggtgttgtc ttggtcgtag
    40441 atgcctatga aggaaccatg ccacaaactc gtttcgtatt gaaaaaagcc ttggaacaag
    40501 accttgtccc aatcgtggtt gttaacaaaa tcgataagcc atcagctcgt ccagcagaag
    40561 tagtggatga agtcttggaa cttttcatcg agcttggtgc agatgacgac cagcttgatt
    40621 tcccagtggt ttatgcttca gcgatcaacg gaacttcttc attgtcagat gatccagctg
    40681 accaagaagc gactatggca ccaatctttg acacgattat cgaccatatc ccagctccag
    40741 tagataactc agatgagcct ttgcagttcc aagtgtcact tttggactac aatgacttcg
    40801 ttggacgtat cggtatcggt cgtgtcttcc gtggtacagt taaggttggg gaccaagtta
    40861 ccctttctaa acttgacggt acaactaaaa acttccgtgt tacaaaactc ttcggtttct
    40921 ttggtttgga acgtcgtgaa atccaagaag ccaaagcggg tgacttgatt gccgtttcag
    40981 gtatggaaga catctttgtc ggtgaaacca tcactccgac agatgcagta gaagctcttc
    41041 caatcctaca catcgatgag ccaactcttc aaatgacttt cttggtcaac aactcaccat
    41101 ttgctggtaa agaaggtaaa tgggtaactt ctcgtaaggt ggaagaacgc ttgcaggcag
    41161 aattgcaaac agacgtttcc cttcgtgttg acccaactga ttcaccagat aaatggactg
    41221 tttcaggacg tggagaattg cacttgtcaa tccttatcga aacaatgcgt cgtgagggct
    41281 atgaacttca agtatctcgt ccagaagtta tcgtaaaaga aatcgacggt gttaaatgtg
    41341 aaccatttga acgtgtacaa atcgacactc cagaagaata ccaagggtct gttatccaaa
    41401 gcctttctga acgtaaaggt gaaatgttgg atatgatttc aactggtaat ggtcaaactc
    41461 gtttggtctt ccttgttcca gcgcgtggtt tgattggata ctcaactgag ttcttgtcaa
    41521 tgactcgtgg ttacggtatc atgaaccata ccttcgacca gtacttgcca ttgattccag
    41581 gggaaattgg tggacgtcac cgtggtgccc ttgtttctat cgatgctggt aaggctacaa
    41641 cttactcaat catgtctatc gaagaacgtg gtacgatctt tgtcaaccca ggtactgagg
    41701 tttatgaagg aatgatcatc ggcgaaaact ctcgtgaaaa tgacttgaca gttaacatca
    41761 cgaaggcaaa acaaatgacc aacgttcgtt cagctactaa ggaccaaaca gctgttatca
    41821 agacgcctcg tatcttgaca cttgaagagt ctcttgagtt cttgaacgac gatgagtaca
    41881 tggaagtaac gcctgagtct atccgtttgc gtaaacaaat ccttaacaaa gcagagcgtg
    41941 agaaagctaa caagaagaaa aaatcagctg aataagagct agaaagagag aaagatggtc
    42001 tatttagtcc taggaatttt actgctccta ctctatgtat ttgcgacacc agaaagcatt
    42061 aaagggacag tcaatatcgt cgctatggta tgtattttag tggcactctt gattttattg
    42121 gttctatctt ttctgaaaat ttttcaatta ccaacagaaa tattcctagc aatagccatg
    42181 ttgatcctag cttactttag tgtgagagac atcacactca tgccagtcaa aaaaagtaaa
    42241 agaagataaa aaagagagtt ttggctctct tttttgctag gaattttaca agattgcaat
    42301 ttatttttga gttatcacca tctcttttgt ttggataata tgaatgggaa aaacttgaat
    42361 aaaatt
//
LOCUS       DAVLMQ010000013        40767 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000013 DAVLMQ010000000
VERSION     DAVLMQ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40767)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40767)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40767
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.013"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..192
                     /locus_tag="VXF95_000838"
     CDS             <1..192
                     /locus_tag="VXF95_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1081414.1"
                     /translation="NAVNAVEQVAAETGYKGDEKLAQARAKVRAELTKYNISMTDKDL
                     DTFVESAVKQMNDAWKGQE"
     gene            192..1148
                     /locus_tag="VXF95_000839"
     CDS             192..1148
                     /locus_tag="VXF95_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1081415.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNTESYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            1418..1660
                     /locus_tag="VXF95_000840"
     CDS             1418..1660
                     /locus_tag="VXF95_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081416.1"
                     /translation="MKILNIELANVEQTDLGFEHWVDVTYNVPILKNEYTVRLLLLFG
                     FEIEDPEVIEYLVNAWKYRELVLHSVRMYDMEREAS"
     gene            1683..2342
                     /locus_tag="VXF95_000841"
                     /pseudo
     CDS             1683..2342
                     /locus_tag="VXF95_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            2335..2763
                     /locus_tag="VXF95_000842"
     CDS             2335..2763
                     /locus_tag="VXF95_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081417.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            2741..3190
                     /locus_tag="VXF95_000843"
     CDS             2741..3190
                     /locus_tag="VXF95_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081418.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREVEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            3218..3529
                     /locus_tag="VXF95_000844"
     CDS             3218..3529
                     /locus_tag="VXF95_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1081419.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            3555..4640
                     /locus_tag="VXF95_000845"
     CDS             3555..4640
                     /locus_tag="VXF95_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HEV1081420.1"
                     /translation="MLKHLNLKGHLLTAISYVIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            4651..5346
                     /locus_tag="VXF95_000846"
     CDS             4651..5346
                     /locus_tag="VXF95_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HEV1081421.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            5383..7353
                     /gene="tkt"
                     /locus_tag="VXF95_000847"
     CDS             5383..7353
                     /gene="tkt"
                     /locus_tag="VXF95_000847"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1081422.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMPLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            7726..8986
                     /locus_tag="VXF95_000848"
                     /pseudo
     CDS             7726..8986
                     /locus_tag="VXF95_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(9061..9591)
                     /locus_tag="VXF95_000849"
     CDS             complement(9061..9591)
                     /locus_tag="VXF95_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HEV1081423.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKISNKGNVYRAIRKSDEQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(9585..10052)
                     /locus_tag="VXF95_000850"
     CDS             complement(9585..10052)
                     /locus_tag="VXF95_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081424.1"
                     /translation="MDLLEKECLKCDKNFQQGDIWNYYYLSDKVPAQGWKIHISSQIK
                     DAVNIFKIVYKLSQLNNCSFKVVKNLEELKKINSPREMSPTANKFITLYPKSESEAKS
                     MICNLTNKLSEFKAPKILSDYQCGMHSPVHYRYGAFLKKQAYDEKIKKSSIYC"
     gene            10592..11269
                     /locus_tag="VXF95_000851"
     CDS             10592..11269
                     /locus_tag="VXF95_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HEV1081425.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLGKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            11256..12053
                     /locus_tag="VXF95_000852"
     CDS             11256..12053
                     /locus_tag="VXF95_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HEV1081426.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLEIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            12070..13173
                     /locus_tag="VXF95_000853"
     CDS             12070..13173
                     /locus_tag="VXF95_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HEV1081427.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTPLASGYQIGEEEFEQVILATGAWLGDMLEPLGYAVDVRPQKG
                     QLRDYQLVQDMEAYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDETLLQQME
                     EATLTHYLILAEATSKSERVGIRAYTSDFSPFFGQVPDLTGVYAASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPENYPIENYVKRVKSE"
     gene            13180..13371
                     /locus_tag="VXF95_000854"
     CDS             13180..13371
                     /locus_tag="VXF95_000854"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081428.1"
                     /translation="MKIKEQTRKLAADYSKHCFEVVDRTDEVSSKHCFEVVDRTDEVS
                     NHTHGKATLTWFELDFRRV"
     gene            13474..14493
                     /gene="galE"
                     /locus_tag="VXF95_000855"
     CDS             13474..14493
                     /gene="galE"
                     /locus_tag="VXF95_000855"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HEV1081429.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTDTLRDIFKQEEPTGIIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLKIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            14495..15448
                     /locus_tag="VXF95_000856"
     CDS             14495..15448
                     /locus_tag="VXF95_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1081430.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(15510..15716)
                     /locus_tag="VXF95_000857"
     CDS             complement(15510..15716)
                     /locus_tag="VXF95_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HEV1081431.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            15768..16244
                     /locus_tag="VXF95_000858"
     CDS             15768..16244
                     /locus_tag="VXF95_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HEV1081432.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            16253..16924
                     /locus_tag="VXF95_000859"
     CDS             16253..16924
                     /locus_tag="VXF95_000859"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HEV1081433.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYIDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            17055..17393
                     /locus_tag="VXF95_000860"
     CDS             17055..17393
                     /locus_tag="VXF95_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HEV1081434.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            17396..18025
                     /locus_tag="VXF95_000861"
     CDS             17396..18025
                     /locus_tag="VXF95_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HEV1081435.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            18265..19416
                     /locus_tag="VXF95_000862"
     CDS             18265..19416
                     /locus_tag="VXF95_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1081436.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            19734..20483
                     /gene="truA"
                     /locus_tag="VXF95_000863"
     CDS             19734..20483
                     /gene="truA"
                     /locus_tag="VXF95_000863"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HEV1081437.1"
                     /translation="MTRYKATISYDGYAFAGFQRQPHARSVQEEIEKTLTRLNKGQTI
                     TVHGAGRTDSGVHALGQVIHFDLPYQMDEEKLRFALDTQSPEDIDVISIELVAADFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IDLILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            20473..21246
                     /locus_tag="VXF95_000864"
     CDS             20473..21246
                     /locus_tag="VXF95_000864"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1081438.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LIKGDKLLPAVESSKAFVYRAIAQADQYGVRQYEANKNN"
     gene            21224..21685
                     /locus_tag="VXF95_000865"
     CDS             21224..21685
                     /locus_tag="VXF95_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1081439.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLIDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNDWAAALPEILPNFMQNMVGMIVGFILSQSIKKIK"
     gene            21960..23172
                     /locus_tag="VXF95_000866"
                     /pseudo
     CDS             21960..23172
                     /locus_tag="VXF95_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(23300..23503)
                     /locus_tag="VXF95_000867"
     CDS             complement(23300..23503)
                     /locus_tag="VXF95_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081440.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(23496..24578)
                     /locus_tag="VXF95_000868"
     CDS             complement(23496..24578)
                     /locus_tag="VXF95_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HEV1081441.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(24704..25486)
                     /locus_tag="VXF95_000869"
     CDS             complement(24704..25486)
                     /locus_tag="VXF95_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HEV1081442.1"
                     /translation="MVYTSLSSKDSNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(25486..26829)
                     /locus_tag="VXF95_000870"
     CDS             complement(25486..26829)
                     /locus_tag="VXF95_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HEV1081443.1"
                     /translation="MNLKTTLGLLAGRSSHFILSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKECTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(26928..28244)
                     /locus_tag="VXF95_000871"
     CDS             complement(26928..28244)
                     /locus_tag="VXF95_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HEV1081444.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYATVAGTGVDIFDAEAHFLS
                     NKVIEIQAGDEKKELTAETIVINTGAVSNVLPIPGLATSKNIFDSTGIQNLDKLPEKL
                     GILGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYMEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAANLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            28437..29663
                     /locus_tag="VXF95_000872"
     CDS             28437..29663
                     /locus_tag="VXF95_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HEV1081445.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPRVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSASGKEKTDSLTQGMTANQALKS
                     NRFYILWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            29862..31436
                     /locus_tag="VXF95_000873"
     CDS             29862..31436
                     /locus_tag="VXF95_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HEV1081446.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQDIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LNEKQTGFVIRNKGDK"
     gene            31701..32489
                     /gene="codY"
                     /locus_tag="VXF95_000874"
     CDS             31701..32489
                     /gene="codY"
                     /locus_tag="VXF95_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HEV1081447.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            32489..33064
                     /locus_tag="VXF95_000875"
     CDS             32489..33064
                     /locus_tag="VXF95_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HEV1081448.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGIFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            33146..33231
                     /locus_tag="VXF95_000876"
     tRNA            33146..33231
                     /locus_tag="VXF95_000876"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:33180..33182,aa:Leu,seq:aag)
     gene            33515..34645
                     /gene="ugpC"
                     /locus_tag="VXF95_000877"
     CDS             33515..34645
                     /gene="ugpC"
                     /locus_tag="VXF95_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HEV1081449.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            complement(34792..34938)
                     /locus_tag="VXF95_000878"
     CDS             complement(34792..34938)
                     /locus_tag="VXF95_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081450.1"
                     /translation="MEIKEKTRKLAVSCSKYSFEVADKTDEVSNHTYGKATLTWFEEI
                     FEEY"
     gene            35146..35904
                     /locus_tag="VXF95_000879"
     CDS             35146..35904
                     /locus_tag="VXF95_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1081451.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAIDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            35991..36503
                     /locus_tag="VXF95_000880"
     CDS             35991..36503
                     /locus_tag="VXF95_000880"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HEV1081452.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            36685..37629
                     /locus_tag="VXF95_000881"
     CDS             36685..37629
                     /locus_tag="VXF95_000881"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HEV1081453.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            37638..38315
                     /locus_tag="VXF95_000882"
     CDS             37638..38315
                     /locus_tag="VXF95_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HEV1081454.1"
                     /translation="MTYLDAFKSGTLVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELFFDASLALERL
                     DDLFGAVRSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFRN
                     AMDLWKD"
     gene            38413..39171
                     /locus_tag="VXF95_000883"
     CDS             38413..39171
                     /locus_tag="VXF95_000883"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HEV1081455.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            39209..40714
                     /gene="lytC"
                     /locus_tag="VXF95_000884"
     CDS             39209..40714
                     /gene="lytC"
                     /locus_tag="VXF95_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HEV1081456.1"
                     /translation="MSVTFFIGEERLKIKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSAEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKIIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
BASE COUNT        12220 a         7333 c         9032 g        12182 t
ORIGIN      
        1 aatgcagtaa atgccgtgga gcaggtagct gctgaaactg gctacaaggg agatgaaaaa
       61 ctggcacagg ctcgtgctaa agtccgtgct gagcttacaa aatacaatat cagtatgacg
      121 gacaaggact tagacacctt tgtggagtca gccgtgaagc agatgaacga cgcttggaaa
      181 ggacaagagt aatggatatc gatagaaaca gactacgaac aggcttgcca caggttgggg
      241 tgcagcctta tcgacaagta cacgcccact caacaggcaa ccgtaactca acagctcaaa
      301 atgaggctga ttaccactat agaaaggacc ctgaactagg gttcttttca catgttgtcg
      361 gaaatggccg tgtcatgcaa gtaggtcctg tgaacaacgg aagttgggat gttgggggcg
      421 gttggaatac tgagagttac gcagcggttg aactgattga aagccattca actaaagaag
      481 agttcatgac ggactaccgc ctttatatcg aactcttacg caatctagcg gacgaagcag
      541 gcttgccgaa gactcttgat acagacgact tggcaggtat caagacgcat gaatactgta
      601 ccaataacca accaaacaac cactcagacc atgtggatcc atatccatat cttgcaagtt
      661 ggggcattag ccgtgagcag tttaagcaag acatcgaaaa cggcttgagc gctgcaacag
      721 gctggcagaa aaatggcact ggctactggt acgtacactc agacggctct tatccaaaag
      781 acaagtttga gaaaatcaac ggtacctggt attatttcga tggctcaggc tatatgcttt
      841 cagaccgctg gaagaagcac acagacggta attggtacta ctttgaccaa tcaggcgaaa
      901 tggccacagg ctggaagaaa atcgctgaga agtggtacta ttttgatgta gaaggtgcca
      961 tgaagacagg ctgggtcaag tacaaggaca cttggtacta cttagacgct aaagaaggcg
     1021 ccatggtatc aaatgccttt atccagtcag cggacggaac aggttggtac tacctcaaac
     1081 cagacggaac actggcagat aagccagact tcacagtaga gccagatggc ttgattacag
     1141 ttaaataaat agaaaggaaa ctttctaaat tgttctttca ccgcaggctc aggcttgcgg
     1201 ttttttattt gctctgattc ttcaaaaaag cgtttacatg aagaataggg aggaggaatg
     1261 gcagggtatt attgccaaaa acgccatttt gttaataata gctccttttt attttttgat
     1321 tattgtcaaa aacggtgttt tgttaaaaat aaaaaaatag tgattttttc ataacttttt
     1381 atcttctttt acgaatagat aagtaggagg aataaaaatg aagattttaa atattgaact
     1441 agcaaatgta gagcagacag atttaggttt tgagcattgg gtagatgtga cttacaacgt
     1501 cccaattttg aaaaacgaat acacggttag attgttgctg ctctttggtt ttgaaattga
     1561 agatcctgaa gtgattgaat acctggtcaa cgcttggaaa tatcgtgagc tggtcttaca
     1621 ttctgtgagg atgtatgata tggagagaga agcaagttaa aatactgtta ctaactctaa
     1681 cttatcttta tcaatacgtt gtatcttcga gattgcaaaa accattttct tccgggaagc
     1741 ttcctttttc tcagcgagtt ttagatgtca ctcattacta ttttagccgt atgtgtatgg
     1801 acaatagaga gattgaaacg acagatcctg actttgttga cttggcgagt catatcagtc
     1861 ccttactgag gagattagat aatagagtac agattaagaa tagtctttta tcacaaattc
     1921 ttttaaccta tcctaatcta gttaaagagt taacaactat ttctaaagaa gtgagtctag
     1981 tatttggttt tgcgtccttg agtctggacg agattggttt tctagtctta tattttgcac
     2041 ggtttcaaga aaagcgagca cgtcctctaa aaacagtagt gatgtgtaca tcaggtgtcg
     2101 gaacttcaga gcttttacga gcacgattag aaaagcaatt tactgaattg gatattattg
     2161 atgtagttgc ttatcatcaa ttagatgagc tgataaatct atatccagat ttagatttca
     2221 ttgtgacgac ggtagctttg caggaaccag caagtgtccc gtttgtccta gttagtgttt
     2281 ttctaaccga gggtgataaa caacgtcttc aagcaaaaat tcaggagata aactatgaat
     2341 aatctttcgc ttgtccttat ggatatatct gttcaaaatc gtcaagaagc ctacaaagaa
     2401 ttagcaaatc aaatcagcct tcttgtttct gaagatacag aaaaaataga agagcttcta
     2461 tattaccgtg agagacaggg aagtatagag gttgctaaag gtgttcttct accacattgt
     2521 gaaggaaact ttcaacatca tgtcttagtg attactagat taaaatcacc tatcagagaa
     2581 tggtcgaagg atatccagtg tgttgacctt attatcggtt tggccattgc agtatcacag
     2641 gacaagtcat gtattaaaac attgatgaga agactagcag atgaatcatt cataaatcaa
     2701 ttaaaacagt taacaaaaga agaattacgg gagataatat atggaaatca aagatattct
     2761 taatgtgagt ctgatccaga cggatttaca gatgcagagc aaagaagagg tttttgaggc
     2821 attagctcaa ctattggttg agacgggtta tgtgtctgat agagaccaat ttatcgaagg
     2881 tctgtatcag agagaggtag aaggacagac cggtattggg aattatattg ctattcccca
     2941 tagcaagagt tctgctgtgg agaaggcggg ggtagtcata gctataaatc acaatgagat
     3001 tccttgggag accattgatg ggaaaggggt caaagtaatt gtactctttg cagttggtga
     3061 tgatacagaa gctgctaggg agcatttgaa gaccttatca ctctttgctc gaaaacttgg
     3121 taatgacgaa gttgttgcca aattagttcg ggctcagaca tctgatgatg tgattgcagc
     3181 tttttgttaa taagaaaaaa ttttggaggg tatccgtatg aaaattgttg gtgttgcagc
     3241 ttgtactgtg ggaattgccc acacttatat tgcacaggaa aaattagaga atgccgcaaa
     3301 ggtagctgga catgtgattc atgttgagac tcaggggaca ataggggtag aaaatgaatt
     3361 gagtcaagag cagattgatg cagcggatgt agttatttta gcagttgatg ttaagatttc
     3421 tggtatggaa cgctttgagg gtaaaaagat tatcaaggtt ccaacagaag tggcagtcaa
     3481 atctcccaat aaactgattg ctaaagctgt tgagattgtt acgaaataac tgaaaatatt
     3541 taaggagaaa atatatgttg aaacacttaa acttaaaagg tcacttattg acagccattt
     3601 cctatgtgat tccaattgtt tgtggtgcag gattcttagt tgccattggt ttagcaatgg
     3661 ggggtggtgt tcctgacgct cttgtagcag gaaaattcac tatctgggat gctttagcaa
     3721 ctatgggtgg taaagccctt ggtctcttgc cagttgttat tgctacaggt ttgtcttact
     3781 cgattgctgg taagccaggg attgcaccag gttttgttgt tggtctaatt gccaattctg
     3841 ttggttcagg gtttatcggt ggtatcttgg gaggttatat agctggtttc ttggttcaag
     3901 cgattattaa aaaggtcaaa gtaccaaact ggattaaagg tttaatgcca accttgatta
     3961 ttccttttgt agcctctttg gtaagtagtt tgattatgat ttatattatt ggagcgccta
     4021 tcgcagcctt taccaactgg ttgacgagct tattacaaag cttgggaagt gcttcaaatg
     4081 gtttgatggg ggcagttatt ggagttctca gtgctgttga ctttggtggc ccacttaata
     4141 aaacagtcta tgcgtttgtg ttgactttac aggctgaagg tgtgaaagaa ccattgactg
     4201 ctttgcaatt ggtgaatact gctacaccag ttggatttgg attggcctat tttatcgcga
     4261 aattactcaa aaaaaatatc tatactcaag aggaaatcga aacattgaaa tcggctgttc
     4321 ctatgggaat tgtcaatatt gttgaaggtg taattccgat tgttatgaat aacttggttc
     4381 caggtctcat tgcaacaggt atcggtggtg ctgttggtgg tgctgtttct ttgacaatgg
     4441 gtgctgattc tgccgtgcca tttggtggag tgcttatgtt accaaccatg actcgtccag
     4501 tagctggtat ttgtgctttg ttagccaaca ttgtagtcac aggacttgtc tacgcgattt
     4561 tgaaaaaacc aataaaacat acagaaccag ttatgactgt tgaagaagag attgatttgt
     4621 cagatattga aattttgtaa gagggtaacg atgtcaagaa ttgaattttc accatctttg
     4681 atgaccatgg atttggacaa attcaaagag cagattactt ttttgaatga taaagtagca
     4741 tcttatcata tcgatattat ggatggccat tttgttccca atattacctt gtctccttgg
     4801 ttcattcaag aagttcaaaa aattagtgac acacctttat cagttcatct gatggtcaca
     4861 gacccaacct tttgggtaga tcaagttctc gatttacaat gtgagtatat ttgtattcat
     4921 gctgaagttc tgaatggtct tgcttttcgt ttgattgata aaattcatga tgcaggtcta
     4981 aaggctggtg ttgtccttaa tcctgaaaca cctgtttcta caatctttcc ctacattgat
     5041 ttacttgaca aagtaactat tatgactgta gatccaggtt ttgcaggaca acgttttttg
     5101 aagtctacct tgtataaaat ccaagaactc cgtcagctta gagttcagaa tggttatcac
     5161 tacatcattg agatggatgg ttcttcgagt cgtaagactt tcaaacaaat tgatgtggca
     5221 ggaccagata tttatgttat aggtcgcagt ggattatttg gtttggatga cgatattgcc
     5281 aaagcctggg atatctgttc tagagattac gaagaaatga ccggaaaaac aatgccaatc
     5341 aaataatggt ttgagaagaa atttattagt taggaggaat atatgtcact acaatcagtt
     5401 aacgccattc gttttcttgg cgtagatgct attaacaaat ctaattctgg tcacccggga
     5461 atcgtcatgg gtgctgcgcc aatggcttat agcttattta caaaacacct tagaattaca
     5521 cctgagcagc caaactggat taaccgagat cgctttatct tgtctgcggg tcatggatca
     5581 atgccactgt atgctctctt gcatttaaca gggtataagg atgtatccat ggacgagatt
     5641 aaaaatttcc ggcaatgggg atctaagaca cctggtcatc ctgaagtgac gcatacgtct
     5701 ggtgtggatg cgacatctgg tccgcttggt caggggattt ctactgccgt tggtttcgcc
     5761 caagcagagc gttttttagc tgctaagtac aacaaagatg gttttcctat ttttgaccat
     5821 tatacttatg ttatcgctgg agacggtgac ttcatggaag gagtgtctgc ggaggcggct
     5881 tcttatgcag gtcatcaagc tttagataag cttatcgtcc tctacgactc caacgatatc
     5941 tgcttggatg gtgagaccaa agatactttc tctgaaaatg ttcgcgcccg ttacgatgct
     6001 tatggttggc atacagttct ggtagaagat ggaacagatt tagcagcaat ttctacagca
     6061 attgagacgg ccaagttttc tggtaagccg agtttgattg aagtgaaaac ggtaattggt
     6121 tacggctcac ccaataaaag tggtacaaat gctgttcatg gtgcaccact aggagcagaa
     6181 gaaacaggag caactcgtaa gtttttggga tgggattacg atccatttga agtaccagag
     6241 gaagtatatt ctgatttcaa gacaaatgta gcggatcgtg gtcaggaggc atacgatgct
     6301 tgggctagtt tggtgtctga ttacaaggtt gcttatcccg aagttgctag tgagattgac
     6361 gctattgtag ctggaaaatc ccctgtaacc attactgaaa aagacttccc tgtctatgag
     6421 aatggcttct ctcaagcaac tcgtaattcg tcccaagatg ctattaatac agcagcagca
     6481 gttttaccaa ccttcttagg tggatcggca gacttagctc actccaacat gacctacatc
     6541 aaggcagatg gcttacaaga taaatataat ccattaaacc gcaatattca gtttggggta
     6601 cgtgaatttg ccatgggaac aatcctcaat ggaatggctc ttcatggtgg tttacgagtt
     6661 tatggcggaa ccttctttgt tttctctgac tacgtcaaag ctgctattcg gctatcagcc
     6721 attcaggagt tgcctgtaac ttatgtcttt acccatgatt caattgccgt tggtgaagat
     6781 ggtccaactc atgaaccagt tgaacatttg gcaggtttac gctcaatgcc aaacttgact
     6841 gttatccgtc cagcggatgc ccgtgaaact caagcggctt ggcatcatgc cttgaccagt
     6901 accaccactc caactgtcat tgtcttaacc cgtcaaaact tggtagttga agaagggaca
     6961 gactttggta aggtcgctaa aggagcctac gtcgtgtatg ataccccggg atttgatact
     7021 attatcattg ctacaggatc tgaggtcaat ctagctatca aagctgctaa ggaattggtt
     7081 ttacaaggtg gtaaagtacg tgtggtatct atgccctcaa ccgaactatt tgatgctcaa
     7141 gatgctacct acaaggaaga cattttacca tctaagactc gtcgtcgtgt ggccattgaa
     7201 atggcagcga cccaaagttg gtacaagtat gttggtttgg atggcgcggt catcggtatt
     7261 gacatcttcg gtgcgtctgc cccagctcag actgtgattg ataattatgg atttacggta
     7321 gagaatatcg ttgctcaagt taagtcccta tagaaaccaa ttacaatgaa gatacagctg
     7381 ttgtcagact agcagatgta gtgatagaca ctaatcagat gattggttat ttaaaaacta
     7441 taatgagaat gtaataattt atctacgaaa gttatagtag atagtataca caatagagta
     7501 taccctgaaa cggttgcgaa gtacgctaat cactttgcta ctgatctaga tagtttcttt
     7561 aatcaataaa cacagcatcc acagattgac ttaggatatt gtaagttttt tgaaagctag
     7621 agagaaggtc tctaaaatta aaaaacgcat agtataggat gttgaaatga tgaactgccc
     7681 cccaaaagtt agacagaaaa aatctaactt ttggggtgtt ttattatgaa attaagttat
     7741 gaagataaag ttcagatcta tgaactaaga aagcaaggac aaagcttcaa acagctttca
     7801 aaaagatttg gtgtggatgt ttctggtcta aagtacatgg tgaaattaat tgaccgttat
     7861 ggcatagagt tcgtcaaaaa aggaaaaaat cgttactatt ctcctgattt aaaacaagaa
     7921 atgattaata aagtcttaca tgaaggctgg actaaagata gagtttctct tgaatacggt
     7981 ctcccaagtc gtacgatact tcttaactgg ctagcacaat acaggaaaaa cgggtatact
     8041 attgttgaga aaacaagagg gagagtacct gagagcggag aatgccatcc taaaaaagtt
     8101 aagagaactc cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa
     8161 ttaatgactg agttttcgtt agctcttctt ctaaaagcca ttaaactagc tcgttcgatc
     8221 tactactatc acttgaaaca gctagataaa ccagataagg accaagagct taaagctgaa
     8281 attcaatcca tctttatcga acacaaggga aattatgctt atcgtcggat ttatttagaa
     8341 ctaagaaatc gtggttatct ggtaaatcat aaaagagttc aaggcttgat gaaagtactc
     8401 aatttacaag ctaaaatgcg acagaaacga aaataaagga gacgttggta agaaggcaga
     8461 gaatctcatt caaggccaat ttgaaggatc taaaacaatg gaacagtgct acacagatat
     8521 gacagaattt gccattccag caagtactca aaagctttac ttatcaccag ttttagatgg
     8581 ctttaatagc gaaattatcg cctataatct ttcaacttca cccaacttag aacaagtaca
     8641 aacaatgttg gaacaggcat tcacagagaa gcactacgag aatacgattc tccatagtga
     8701 ccaaggctgg caataccaac acgattctta tcatcggttc ttagagagta agggagttca
     8761 agcatctatg tcacgcaagg gtaatagccc agacaatggt atgatggagt ccttctttgg
     8821 gattctgaaa tcggaaatgt tttacggtta tgagaagtcg tttcagtcgc ttaagcaatt
     8881 ggaacaagct attgtagact atattgatta ctacaacaat aaacgaatta aggtaaaact
     8941 aaaaggactt agtcctgtgc aatacagaac taaatccttc ggataaatta attgtctaac
     9001 tttttggggg gcagtacatt tttggtatat ataaaatttg taggagctat atctacaatt
     9061 ttatattccc agtttatgga tgtcgcttac tatattcaca atgttatcca gtgttttttc
     9121 tctaatattt aaggagtgtt ctgtttctcg aataaattct tcaaagttta acccgtcaac
     9181 ttgttcctga acaagaaaat aatcatccac gatataaaat tcatcagtta aattagtagt
     9241 ataactttta tcggctaatt tttttagcat gtaagcctca ttttttatat catcaagtgc
     9301 tgtccattct ccttcggcat cataattcac aaaaggtctt gactgcttga tgattacttt
     9361 ttgctcgtcc gattttctaa ttgcccgata aacatttcct ttatttgata tcttaataat
     9421 tttttctatt ttgtatttat ttattgcaga gtccttactt gaaacttcac atgtggtttg
     9481 aaaataaatc cttttttctt cttctgaaaa taaatccatt ttccagctag gaagactagg
     9541 gaaattttgt ctcttatctt ctacatagtt cttccttttt tcatctagca ataaatagat
     9601 gactttttta ttttttcatc ataagcttgt ttttttaaaa aagccccata tctataatga
     9661 actggagaat gcattccaca ttgatagtca gatagtattt ttggagcctt aaattctgac
     9721 agtttattcg taagattaca aatcatactc ttggcttcag attctgactt aggatataga
     9781 gttataaatt tgttagcagt agggctcatt tccctagggg aattaatttt ttttaattcc
     9841 tctaaatttt taacgacttt aaagctacaa ttatttagtt gggatagttt atacacaatc
     9901 ttaaaaatat ttacagcgtc ttttatttgg gagcttatgt gtattttcca gccttgtgca
     9961 ggcaccttat ctgataaata atagtaattc caaatatcac cctgttggaa atttttatca
    10021 cattttaaac attctttctc taataaatcc ataacaaact cctaattatt aaaataggct
    10081 agagacacag cactagccta ttccgtaagt aaagctactt attttatata aaatataact
    10141 agcgacctgt aattaaacaa gtaaaagaac aatacttagg gagacctgtg acaatgacat
    10201 cttcctctgg aagtagttct aattcaaaca atgtttgttc catgactgta tcctcctgtt
    10261 atgataaatt ccagaaagca tagagcaaat tcgtggttcg tctgactaaa tttcttatct
    10321 gaacaccacc ttcaaataca aattttagtc aaacttttat tttttctaac tttctaatta
    10381 tattctacca tgtgttttta tatgtcaaga attttctgaa taaactgttt attttttatt
    10441 ttttgcaaat tgtttaaaat ctttcaattg gattcactta ttactttagg acattgaaac
    10501 ttctttcgcc agaggtgctt atattactgg gaagttgaag attgaaatgt ggtataataa
    10561 gaggtaatag agttttggaa agagagagaa gatgatttca aagagattag agttggtagc
    10621 ttcctttgtg ccgcagggag ccattttact agatgtgggg agtgaccatg cttatttgcc
    10681 tatagagtta gtcgaaagag gaaaaatcga aagtgccatt gcaggtgaag ttgtggaggg
    10741 accttatcag tctgctgtca aaaatgttga ggcccacggc ttggaagaaa aaatccaagt
    10801 ccgtttagcc aatggtttgg cagcttttga agaggaagac cgagtgtctg tcattaccat
    10861 tgctggcatg ggtggtcgtt tgattgctag gattttagaa gaaggtttgg ggaagttagc
    10921 taatgtagag cgtttgatcc tccagcccaa taatcgtgaa gacgacttgc gtatctggct
    10981 acaggatcat ggattccaga ttgtagcaga aagcatctta gaagaagctg gaaagtttta
    11041 tgagattttg gtggtggaag caggacaaat gaagctatca gccagtgatg ttcgctttgg
    11101 tcccttcttg tccaaagaag tcagtccagt atttgtccaa aaatggcaaa aagaagctga
    11161 gaagctagag ttcgccctcg gacaaatccc agaaaaaaat ctggaagaac gtcaagttct
    11221 agtagataag attcaagcta tcaaggaggt gctccatgtt agcaagtgaa gtgatccaag
    11281 cttatgaagc cttttgccct caggaatttt ctatggaggg agacagccgt ggtctgcaaa
    11341 ttggcacttt agacaagggt atccaaaggg tcatggttgc cctcgatatt cgtgaagaga
    11401 cagtggcaga ggccattgaa aagggtgtgg acttgattat cgtcaagcac gcgcctatct
    11461 ttcgtcctat caaggacttg cttgccagcc gtccgcaaaa tcagatttac atcgacctga
    11521 ttaagcatga catcgcagtt tatgtcagcc ataccaatat tgatatcgtt gaaaatgggc
    11581 tcaatgactg gttttgtcag atgctagaaa tcgaggagac gacttatctg caggaaacag
    11641 gtccagaacg tggaattgga cgtattggga atattcagcc tcagacattt tgggaattgg
    11701 cccaacaggt caagcaagtc tttgacctag atagccttcg aatggtgcat tatcaagaga
    11761 atgatttgca gaagcctatt tcaagagtag caatttgtgg tggaagcggg cagtctttct
    11821 ataaggatgc tttggcaaag ggggcagatg tctatatcac tggtgatatc tactaccata
    11881 ctgctcagga tatgctgtct gatggcttgt tagcattgga tccaggtcac tatatcgaag
    11941 tgctttttgt ggaaaaaatc gcagcactcc ttactcaatg gaaagagaaa aaaggctggg
    12001 aactagagat tttacctagt caagcatcga ccaatccttt ccgtcatatc tagttagaaa
    12061 gtgaagacaa tgaaaaaagt tgccattatt ggagcaggaa ttgtgggagc aacagctgcc
    12121 tactacctct cgagagaaag tgacctagag gtgaccgttt ttgaccatga gcaaggtcaa
    12181 gccaccaagg ccgcagcagg aattatcagt ccttggtttt ccaaacgccg taataaagcc
    12241 tggtacaaga tggcgcgctt gggggctgat ttttatgtgg atttattagc tgatttagag
    12301 aaatcaggac aaaaaatcga cttttaccag cgttcgggag tctttctctt gaaaaaggat
    12361 gaatccaagt tggaagaact ttatcaactg gccctccagc gcagagaaga atctcccttg
    12421 atagggcaat tagccattct ggaccaagcc tcagctaatg aattattccc tggtttgcag
    12481 ggatttgacc gcctgctcta tgcttctggt ggagcgagag tagatggcca actcttggta
    12541 actcgtctgc tagaagccag tcatgtcaag ctggtcaaag aaaaagtgac tctgacaccg
    12601 ttagcatcag gctaccagat tggtgaagag gagtttgagc aggttatttt ggcgacggga
    12661 gcttggttgg gggacatgtt agagccttta ggttatgctg tggatgtccg tcctcaaaaa
    12721 ggacaactac gagattatca gctggtccaa gatatggaag cttaccctgt tgtcatgcca
    12781 gaaggggagt gggatttgat tccttttgca ggtgggaaat tgtccttagg cgctacccac
    12841 gaaaatgaca tgggatttga tttgacggta gatgaaacct tgctccaaca aatggaggag
    12901 gccaccttga ctcactatct gattttggct gaagctactt caaaatctga gcgtgttgga
    12961 atccgtgcct acaccagtga tttctctcct ttctttgggc aggtgcctga cttaactggt
    13021 gtctatgcag ccagtggact aggttcatca ggcctcacaa ctggtcctat tattggttac
    13081 catttagctc aactgatcca agacaaggag ttgaccttgg accctgaaaa ctacccaatt
    13141 gaaaactatg tcaaacgagt aaaaagcgaa taatactcaa tgaaaatcaa agaacaaact
    13201 aggaaactag ccgcggatta ctcaaagcac tgctttgagg ttgtggatag aactgacgaa
    13261 gtcagctcaa aacactgttt tgaggttgtg gatagaactg acgaagtcag taaccatacc
    13321 catggcaagg cgacgttgac gtggtttgaa ttggattttc gaagagtata agcattttac
    13381 tgaaatttta tcaggtagtt taggatggca aatgacattc cctgtcaaaa atggtaaaat
    13441 aagaaaaaat aatctgagaa tcgaggaaaa aagatgcaag aaaagatttt ggtaactggt
    13501 ggtgccggtt ttattggaac ccacactgtt attgaattga tccaagcagg ccatcaagtt
    13561 gttgtggtgg ataatcttgt caatagcaat cgtaagagtt tagaagttgt tgaaagaatc
    13621 acaggagttg agattccttt ctatgaggca gatattcgtg acacagatac cctcagagat
    13681 attttcaagc aggaagaacc gactggtatc attcactttg ctggtttgaa ggctgttggc
    13741 gaatcaacac gtatccctct tgcctactat gacaacaata tcgctggaac tgtcagcctt
    13801 ttgaaagcca tggaagaaaa caactgtaaa aacatcatct tcagttcttc tgcgacagtt
    13861 tacggggatc cgcacacagt gcccatcttg gaagatttcc cactttcagt gaccaaccca
    13921 tacggtcgta ccaagctcat gctagaggaa attttgaccg atatttacaa agcagactca
    13981 gaatggaatg ttgtcttgct tcgttacttt aacccaatcg gagcccatga gagtggtgat
    14041 ttgggagaaa atccaaacgg tattccaaac aatctcttgc catatgtgac tcaagtagcc
    14101 gttggaaaat tagagcaagt gcaagtgttt ggagacgatt acgatacgga agatggaaca
    14161 ggtgttcgtg actatatcca cgttgtcgat ttggctaagg gtcacgttgc agctttgaaa
    14221 aaaatccaaa aaggttcagg actaaacgtt tataaccttg gaactggtaa aggttactca
    14281 gttcttaaaa ttatccaaaa catggaaaaa gcggtgggac gtcctattcc ttaccgcatc
    14341 gtagaacgtc gcccaggtga tatcgctgcc tgctactcag acccagcaaa agctaaagca
    14401 gaactcggtt gggaagcaga actcgacatc acccaaatgt gtgaagacgc atggcgttgg
    14461 caaagcaagc atccaaatgg atttgaagac taagatgatg atttcaatca tcgtcccttg
    14521 tttaaacgaa gaggaagtac ttcctctttt ttatcaggct ctggaagctt tacttccaga
    14581 tttggaaaca gaaatcgagt atgtctttgt cgatgatgga tcaagtgatg ggaccttgga
    14641 actcttaaag gcctatcggg agcaaaatcc ggcagtccat tatatttctt tctctcgaaa
    14701 ttttggcaaa gaagcagccc tttatgcagg cttgcaatat gcgacaggag atttggtggt
    14761 ggtgatggat gcagacctcc aagatcctcc tagtatgttg tttgagatga aaaatgtact
    14821 agacaaaaat gtagacttgg actgcgttgg gacacggaga actagtcggg agggagaacc
    14881 cttctttcgc agtttctgtg ctgttctctt ttatcgcctc atgcaaaaaa tcagcccagt
    14941 agctctgccg tcgggtgtcc gtgattttcg tatgatgaga aggtctgtgg tcgatgccat
    15001 tttaagcttg actgagtcca atcgtttttc taagggactc tttgcctggg tcggctttaa
    15061 aacccactat ctggactatc caaatgtcga aaggcaggct ggcaagacca gttggagttt
    15121 taggcaactc tttttttact ccattgaagg gattgttaat ttttcagatt tccctttgac
    15181 tatagccttt gtagctggtc tcctatcttg ttttctttct ctgctgatga ccttttttgt
    15241 tgtggttcgg accctcattt tgggcaatcc gacatctggt tggacctctc tgatggctgt
    15301 tattctcttt cttggaggca ttcaactctt gaccattggg attctcggta agtatatcag
    15361 taagatttat ttagagacta aaaaaagacc actttatctt atcaaagaaa aaagtgacct
    15421 tcctgatttt acagaaaaaa taaagtgaaa agactataat tttacatgga aatgtgctaa
    15481 actagaggga gtggattatc gccattgatt taggcttcct ggtttccaat cagggcgcga
    15541 gttgggcaat ttttaacagc ctctaagaca tcctgactag gagaaatttc tttttccagt
    15601 tggtcagggt catcgtaaaa acgcacgatt ccattatcgt ggtaatcaaa taaatcagaa
    15661 taagtttggc aaagtccaca ggcgatacat cgttcaggta taagtgtgat tttcatgttc
    15721 atatttatat tgtaataaga aaagtaaaaa aaaacaagga gtaaggtatg gcaaaagaac
    15781 cgtggcaaga agatatttat gatcaagaag aatcaagagc agggcgtcgg catcgaaacc
    15841 acggaggggc tgataggatg gctaatcgta ttttgacgat cctagctagt attttctttg
    15901 taattgtggt ggtgatggtc atcgttctca tctatctatc atcggggggg agcaatcgca
    15961 cagcagcctt aaaagacttt catgattctg atgcaagtgt agtacaaatc tcatcttcaa
    16021 gcagttctca gcctgagcag agttcagagc cagaatctac ttctagtagt tcagaagaag
    16081 ctgctaatcc tgaaggaacg attaaagttc tcgcaggaga aggggaagca gctattgccg
    16141 ctcgtgcagg aatctccatt gctcagttag aggccttgaa tcctgggcac atggctacag
    16201 gatcttggtt tgctaatcca ggtgatgtta taaaaataaa ataggagccg atatgaaaac
    16261 aattcaaatt gctattgatg gtcctgcttc cagcggtaag agtacggtcg caaagattat
    16321 tgctaaggat tttggattca cctaccttga tacaggagct atgtatcgtg cagcgaccta
    16381 tatggctctt aagaaccaat taggagttga agaagtcgaa gcccttctag ccttgttgga
    16441 ccagcatcca atcagctttg gacgttcaga aactggagac cagcttgttt ttgtaggaga
    16501 tgtggatatt acccatccta tccgtgaaaa tgaagtgacc aatcatgttt ctgctattgc
    16561 agcaattcct gaagtgcgtg agaaactggt ttctctccaa caagaaattg cccagcaagg
    16621 cgggattgtc atggatggtc gcgatattgg aactgttgta ttgccacaag cagaattgaa
    16681 aattttccta gtagcttctg ttgatgagag agcagagcgt cgttacaagg aaaatattgc
    16741 caagggaatt gaaacagacc ttgaaaccct aaaaaaggaa attgctgcgc gtgactacaa
    16801 ggatagtcat cgtgagactt ctcctctcaa acaagcagag gatgctgtct acattgatac
    16861 aactggtttg aacattcaag aagtagttga aaaaatcaaa gcagaagctg aaaaaagaat
    16921 gtaaatgtag aaaagccgat agattgatat cggttttttt ctaaatttgt caaaatgctg
    16981 attttagggt ataatagttg ctgttcgaga aattttgatt ttcaaagaat agtgaatgat
    17041 gataaggaga aaccatgaac aatttaccaa attgtccaaa atgtaactca gagtatgtct
    17101 acgaagacgg tgccctactg gtttgcccag agtgtgctca tgagtggaat cctgctgaag
    17161 ttgcagaagt agaagaaggt cttgtcgcta tcgatgccaa cggaaataaa ttgactgatg
    17221 gtgatacagt aactctcatc aaggacttga aagtaaaagg tgcgccaaaa gatttgaaac
    17281 aagggacgcg cgtgaaaaat atccgcatcg tagaaggcga tcacaatatc gactgtaaga
    17341 ttgatggttt tggtgccatg aaacttaaat cagagtttgt gaggaagatt taagcatgtc
    17401 aaaacactat aaacttgtat tttatagccg tatcttcttg tttctagcgg cttttacggg
    17461 agtttatctt gaaattacta ggcatggtgg ttttgggatg cttctctatt acacggttct
    17521 gtccaacctc ttggtaacta tttttaccct ttatcttcta aaggttatga gccgtgtagg
    17581 tgaaaattgg caaaggccaa gtctcttgcg cttaaaaggt ggggtcacca tgagtatcat
    17641 gattacctgt gtgatttacc atttcctctt ggcgcccatt gcgactaatt tctataccct
    17701 agaaaatttc ctttgccact atatcgttcc catctggttt ttagcggata ccctcttttt
    17761 tgacaaacag ggtcaataca agatttggga tccagcagtg tggaccattt taccctttct
    17821 gtatatgatg tttgctcttt ttaatggctt ggttctaaaa ctcaatattc caaatgccaa
    17881 ggataatcct ttcccttact tctttttgaa tgtgaacaag ggttggaatg ttgtgtttaa
    17941 gtggtgtctg attatctttg ttgcctatat ggtagcagga tttattttct actttatcaa
    18001 gcaaatcaag agaaagtcat cctaatactc ttcgaaaatc tcttcaaacc acgtcagttt
    18061 ccatctgcaa cctcaaaaca ctgttttgaa caacctgcgg ctagcttcct agtttgctct
    18121 ttgattttca ttgagtataa gatacaaggg attcattttc gaatttaaga aggagtctac
    18181 aaaccaatga ggcttcttct tttcttgctt atttgataac tatcaaaaaa gtagaagatt
    18241 aagagaaata tagaaagaga tttcatgaaa caatttttag aacgggccag cattttggct
    18301 ctctccctcg ttttgattac ctccttttcc atttcgagtg ccctaccagc catgtttgac
    18361 tattatcagg gttattctaa ggaacaaatt gagctcttgg tgagcttgcc ttcctttgga
    18421 atcatgatga tgttactgct aaatggtttc ttagaaaaaa tatttcctga gcgcttacag
    18481 attagtttgg gcttgctgat tttatcattg agcggtacag ctcccttctg gtaccaagcc
    18541 tatccctttg tctttggaac acggcttctc tttggtttgg gtcttgggat gatcaatgcc
    18601 aaggccattt ctattatcag tgaacgctac caaggaaaaa ggcgaattca gatgttaggg
    18661 ctacgcgctt ctgcagaggt cgttggagct tctctcatta ccttggccgt cggtcagttg
    18721 ttggcctttg gttggacagc tatctttcta gcctatagtg ctggattttt ggtgctgccc
    18781 ctttatctgc tctttgtccc ttatggaaaa tcaaagaaag aagtcaagaa aagagcgaag
    18841 gaagcaagtc gtttaactcg agaaatgaaa ggcttgattt ttaccttagc tatcgaagcg
    18901 gcagttgtag tttgtaccaa tacagctatt accatccgta ttccaagttt gatggtggaa
    18961 agaggattgg gggatgccca gttatctagt tttgttctta gtatcatgca gttgatcggg
    19021 attgtggctg gggtgagttt ttctttcttg atttctatct ttaaagagaa actgctcctc
    19081 tggtctggta ttacctttgg cttggggcaa atcgtgattg ccttgtcttc atccttgtgg
    19141 gtggtagtag caggaagtgt tctggctgga tttgcctata gtgtagtctt gacgacggtc
    19201 tttcaacttg tctctgaacg aattccagct aaactcctca atcaagcaac ttcatttgct
    19261 gtattaggct gtagtttcgg agcctttacg accccattcg ttctaggtgc aattggctta
    19321 ctaactcaca atgggatgtt ggtctttagt atcttaggag gttggttgat tgtaatctct
    19381 atctttgtca tgtacctact tcagaagaga gcttaggatt gattcctaag tttttctttt
    19441 gatactcaat gaaaatcaaa gagcaaacta tagttgattg agtttggaat agtacgctgt
    19501 agctgctaaa atatttctag aaattaattt gactttccta atagagttgt tcatatctta
    19561 tttcaatcta ctatagaaag ctagccgcag gttgctcaaa atagtgtttt gaggttgcag
    19621 atggaaactg acgtggtttg aagagatttt cgaagagtat gagattttta tacccataca
    19681 atatttgttt taggtccttg tttacagact aatttcttga taaaatagag gttatgacga
    19741 gatataaagc aactatttcc tatgatggtt atgcctttgc tggctttcag cgccagcctc
    19801 atgcgcgtag cgttcaggaa gaaattgaaa aaaccttgac cagattaaat aaagggcaaa
    19861 ccattactgt tcacggtgct ggtaggacag atagtggggt tcatgccctg ggacaggtca
    19921 ttcattttga cctgccttat cagatggatg aggagaaact ccgttttgcc ttggataccc
    19981 agtctcctga agatattgat gtgatttcga ttgagcttgt ggcagctgat tttcattgcc
    20041 gttatgccaa gcatagcaag acctatgagt ttattgtgga tagaggacgt cccaaaaatc
    20101 cgatgcgccg tcactatgcc acccactttc cctacccact cgatgtggaa cgaatgcaga
    20161 ttgcaatcaa aaagctagag ggaacccatg attttaccgg ttttacagcc tctgggacta
    20221 gtgtagagga taaggttcgc accatcacag aagctagttt aatagtcgat gagacaggac
    20281 aatttttgac ctttaccttt tccggaaatg gtttcttgta taaacagatt cgcaatatgg
    20341 tggggactct tctcaaaatc ggtaacaacc gcatgccagt agagcagatt gatctcatct
    20401 tggagaagaa ggacaggcaa cttgcaggtc ccactgcagc accaaatggt ttgtatttaa
    20461 aggagattcg ttatgaagaa taatcgtatt ttagcacttt ctggaaatga tatttttagt
    20521 ggtggtggac tgtcagctga tttggctacc tataccttga acggcttgca tgggtttgta
    20581 gcagtgactt gtttgacagc cttgacagaa aaaggatttg aagtctttcc aactgatgat
    20641 accatttttc aacatgaatt agatagcttg cgtgatgtgg aatttggggg aattaagatt
    20701 ggtcttctcc ctactgtcag tgtggctgag aaggccttgg actttatcaa acaacgccca
    20761 ggagtacctg tggtgttgga tcctgtcttg gtctgcaagg aaacgcatga tgtagctgtc
    20821 agtgagctct gccaagagtt gattcgcttt ttcccttatg tcagtgtgat tacgcctaat
    20881 ctcccagaag cagaattatt atccggtcag gaaattaaaa ccttggaaga catgaaaact
    20941 gcagcgcaga aattgcatga tttaggagcg ccagcagtca ttatcaaggg aggcaatcgt
    21001 cttagtcagg acaaggctgt ggatgtcttt tatgatggac agacctttac tatcctagaa
    21061 aatccagtta tccaaggcca aaatgctggt gcaggttgta cctttgcctc tagcattgcc
    21121 agtcacttga ttaaaggtga taaacttttg ccagcagtag aaagctctaa ggctttcgtt
    21181 tatcgtgcta ttgcacaagc agatcagtat ggagtaagac aatatgaagc aaacaaaaac
    21241 aactaaaatc gcccttgtat ccctattaac cgccctttct gtggttctag gttatttctt
    21301 aaaaatccca acacctacag gaattctaac tcttttagat gctggtgtct tctttgcggc
    21361 cttttacttt ggtagtcgtg aaggagcggt agtcggagga ctagcaagtt tcttgattga
    21421 cctcttatca ggctaccctc agtggatgtt ctttagcttg gtcaaccatg gcttgcaggg
    21481 atttttcgca ggatttaaag gaaaaagtca gtggttaggc cttattttag caactattgc
    21541 catggtagga ggctacgcct tgggttctac tttgatgaat gactgggcag cagccctccc
    21601 agaaattcta ccaaatttca tgcaaaatat ggtagggatg attgtaggat ttattcttag
    21661 tcaaagtatc aagaagatta agtaatactc ttcgaaaatc tcttcaaacc acgtcagctt
    21721 gtccttagtg tgtatatgtt actgacttgg tcagttctat ccttaacctc aaaactatgt
    21781 ttcgaggagc cttccgctaa cttcccagtc tgagtttcat tgaatattaa cgatacttta
    21841 tcacataaag aggctggatg aaaagtcttc acaatcaaaa aaacgcatca tatcaggtgt
    21901 acatgaacta caccccaaaa gttagacaga aaaaatctaa cttttggggt gtttttatta
    21961 tgaaattaac ttatgatgat aaagttcaga tctatgaact tagaaaacaa ggatatagct
    22021 tagagaagct ttcaaataaa tttaggataa acaattctaa tattaggtac atgattaaat
    22081 tgattgatcg ttacggaata gagttcgtca aaaaaggaaa aaatcgttac tattctcctg
    22141 atttaaaaca agaaatgatt aatcaagtct tacatgaagg ctggactaaa gatagagttt
    22201 ctcttgaata cggcctccca agtcgtacga tacttcttaa ctggctagca caatacagga
    22261 aaaacgggta tactattgtt gagaaaacaa gagggagagt acctaaaatg ggacgtaagc
    22321 caaaaaagag acctgaagag aggacagaat tagaatatct tcaagcagaa aatgagtacc
    22381 tgagagcgga gaatgccatc ctaaaaaagt taagagaact ccgattgaag gaggaaaaag
    22441 agaaagaaga aagacagaaa ttgttcaaga attaatgact gagttttcgt tagatcttct
    22501 tctaaaagcc attaaactag ctcgttcgac ctactactat cacttgaaac agctagataa
    22561 accagataag gaccaagagc ttaaagctga aattcaatcc atctttatcg aacacaaggg
    22621 aaattatggt tatcgtcgga tttatttaga actaagaaat cgtggttatc tggtaaatca
    22681 taaaagagtt caaggcttga tgaaggtact caatttacaa gctaaaatgc gacagaaacg
    22741 aaaataaagg agacgttggt aagaaggcag agaatctcat tcaaggccaa tttgaaggct
    22801 ctaaaacaat ggaaaagtgc tacacagatg tgacagaatt tgccattcca gcaagtactc
    22861 aaaagcttta cttatcacca gttttagacg gctttaacag cgaaattatt gcttttaatc
    22921 tttcttgttc gcctaattta gaacaagtac aaacaatgtt ggaacaggca ttcacagaga
    22981 agcactatgg tggagtcctt ctttgggatt ctgaaatcgg aaatgtttta tggctatgag
    23041 aaaacattta aatcacttaa tcaattggaa caagctattg tagactatat tgattactac
    23101 aacaataaac gaattaaggt aaaactaaaa ggacttagtt ctgtgcagta cagaactaaa
    23161 tcctttggat aaattaattg tctaactttt ggggggcagt acattttaac acttgataat
    23221 atgcgtttta ttgtgggaag attttcctca ttttctagtg aaattgaact ttttctaaca
    23281 tcttttgata gatgacttct taatcaatta tcatttccat tgttgtttct tggggtttca
    23341 tcccttgtct ttgataaaag cggagagcac cctcgttatc attccagaca cttagggtta
    23401 gattattgca gccaatttct ttagcataat agcagaaaaa tgacaataaa atagccccta
    23461 gatattttga aaggaaagca taggggctat atagtttaat caaaataaag caaatctttg
    23521 ctggtgcttg taaagaggtc gaagccatcc ttggtaacaa caccgcagtc ttcaatacga
    23581 acaccgactt taccagggat atagatacct ggttcaacag agaagcacat gccttcttcg
    23641 atgaccatgt cgtttccttc catgatagat gggaattcat ggacatccat accgatacca
    23701 tgcccgagac ggtggttgaa gtactcacca taaccagctt tttcgatgac ctcacgggca
    23761 gcgcggtcca cttcatgagc agtcacacct ggcttgataa agtcaagagc agcttgttgg
    23821 gcttcaagag tcaagttgta aatatctttc ttgaattggt ctggtttgcc gacagcgact
    23881 gtacgagtca tatctgacgc atagccattg accagaacac ccaggtcaaa gaggagaaga
    23941 gcatcatttt caaccttatt agctgctgga atgccgtgtg gattcgcagc attatcacca
    24001 gtcaagacca tggtatcaaa gctcatttcg taaccttcac gtttcatggc aaagtcaatt
    24061 tgtgcgatga tatctgtctc agtcttatca agagaaatat tgtcaaaacc aacatgaaca
    24121 gccttgtcag cataaagacc tgcaaccatc attttttgca cttcatcagc tgatttgatg
    24181 aggcgcatgc gttggatacg aggagtgagg ttgtcaaact cagcagtctc aaaaactgtt
    24241 ttcaaaccat ggtatttggt caagatgaga ttgtcaaact caacagcgac acgtttgaag
    24301 tcaagttgtg gaagagcatg tttgattttt tgccatggat tttcagaatc gacatagccc
    24361 actactggga aggaaacggt gctacttgca cgttctactt caagagctgg gacaaagagg
    24421 agaggttcct gatccgctag gacaaagagg aacatttggc gttcatgggg atcactgtaa
    24481 aaaccagtga ggtaattgat tgtgacgggg tcagatacga cagcgacgtc tagtttttct
    24541 gattcaagat atgttaggat ttgttgtaat ttagacatat gctaccttct ttctacccct
    24601 ctattttggc aaaaaatgag agaaaatgca agggagaagg gtaaaagaaa agacaaaaaa
    24661 ctccgacaag ataacggagt tctttgatat cattttcctt tgtttaagaa aagtcagcct
    24721 tgcttttgac gtcactgtac tcttcagcga tttcttggct gagaatgtcc tcataggcag
    24781 ggagttggat gtcctgacca tatttcttct tgagggcagt agtaactagg cgataagcca
    24841 gattggcatt acgagagagg ataggcccgt ggaagtagga accaaagaca ttcttataat
    24901 gaaccccttc accgaccttt tcttcgttgt ttccatttcc atagacaacc tgtcccagcg
    24961 gtttttggtc atcagagagg aaggtacgac cttggtgatt ttcaaatcca tagtaggttt
    25021 catcgaaatc ttcattgtga atcttgatgt caccgataaa acggttattg gtctggttga
    25081 gcgtgtagtg tcccatgacc cctagccctt cgatacgttt tcctgaagct tcaacataat
    25141 attgacccaa tagttggaaa ccaccgcaga tagccagaac tacaccgtcg ttttggatgt
    25201 agttgtcaat gctctctttt ttagcaggta ggtcgtctgc aatgatactt tgttcaaagt
    25261 cttgaccacc accgaaaaag gcgatgtcgt agtgattttc atcaaagtca tcatggagag
    25321 aaacgatgtc aacggtcaca tgggctccca gtttttcagc cacatacttg agcatgagga
    25381 tgtttccatt gtccccgtag gtattcatga gatttccgta gaggtgggca atgttgagct
    25441 gataggggta attgctatct tttgaggaaa gtgaagtata aaccattagt tcatctcctt
    25501 tctaacaatc tgacgactag ccagcagttc acgaaattcc agcatggcag tataagttgc
    25561 cagaatatag gcatgcttgc agtcttgatt ctcaatggtc ttgagaactt gctccagatt
    25621 actcgtttca gtgattttct cagctggata gccagtcact cggaggcgac gagcgatttc
    25681 agaatgacga acaccgccag cgttgatttc aggaatgtcc atgtcagtga tttgctcaaa
    25741 gtctgcatcc cagatccagc tagtgtcaat tccatctgca tagttggcat taaggaggac
    25801 agataggcta aatggataag gtgctagttt gatcatttcg atagcttggg ttgcaccgac
    25861 tggattttta atcaagacaa gggtacattc cttgtcaccg atatgaaagg tttcttggcg
    25921 tccaaagaca gcacggctct tgtcaaatcc ctgtttgatg agttgcgaat cggcacctag
    25981 gaaacgggcg atggccacag cagctagggc gttatagata ttatagagcc cgccgatttg
    26041 gataccgtat tcttggccgt ctatgacaaa gcgagagcga ttgttggtca actcaaccaa
    26101 ttttgtcaaa cgatagtcga gatcaggacg tttacatcca caaccttcac agatataggc
    26161 acccaagttt gcataggtat tatgctcata tttgaggatg ccttggcagt caggacagag
    26221 aatcccttcg gtattgtagt gagccagttg ggctggtcct ttttccaagt caaaaccaaa
    26281 atactctata gggtttggaa tagttggctt gtagaaaagt ggactgtctc cgttaaggag
    26341 aacagtagca gttggaactt tccgaatggc atccaatatc atgttatagg tagtatagat
    26401 ttcaccgaaa cggtccatct ggtcacggaa gatattagta atgacaaaaa gactaggctg
    26461 gatatagtca cagatacgag atagactggc ttcgtcaatt tcgaggacgg caatattttt
    26521 tccagtttta gaagatttgg ctgttaggaa ggttgttgca atccctgtaa tcatgttggc
    26581 accgcttgga ttggttagaa cttgaccata gacctctttt aaaatgccga cagtgagggc
    26641 agttgtcagg gtttttccat ttgttccagt gacaacgaca atctcgtagt tcttagctag
    26701 gttttgtaaa atatctttat caaattgaag ggcgacttta cctgggagcg tacttccacg
    26761 gccaagacgg cttaaaatga agtgggaaga acgcccagca agaaggccca aagtagtttt
    26821 taagttcatg tttctattat atcataaaag aggagaaaga cagatttgag attccgcaga
    26881 agtaaaaaca gcccaaagag ggctgttcga tacgattaaa tctcaactta aatcgcaaac
    26941 aagtcattca agttctcagc caaggttggg tgagtgaaga tttgttttgt gaagtaagtg
    27001 taaggaatct tgttgtccat agcaacagta ataatgttga tgatttcttg agaaccttct
    27061 gagaagatgc ttgcaccaag aatttctttt gtttcagtat taacaacagc tttgaaagct
    27121 ccgcgaaggt ctccatttac gtgaccacga ggcatggctg caacagggat ttctttcact
    27181 gcgtatggaa gtttcaaatt agctgcttgg ctttcagtca aaccaacttg tgaaagtgca
    27241 ggtgtgatga acatagtatt tggcacattg agacggtcct caagtgtgta gctgccatct
    27301 ccagcaaggt agctgtaaac aacacggaag tcatcaagtg aaatgtaagt aaattgaaga
    27361 ccaccgttga catctccaac tgcaaagaca ccaggaacgt ttgtttgaca gtgtttatct
    27421 actttaatag cgccacgttc agttagttca atatctgtat tttcaagttg aagtggttct
    27481 acatttggtt tgcgtccagt tgcgtagaga agggcgtcga aacggtaagt ttcgtcttca
    27541 gttacgacaa gcacttggtc accgtcgttt ttaatttcag tagtatggat attttgaagc
    27601 aattcaatgc catcttcttc catgtattgt ttagcaagag ctgcgatgga aggttctgca
    27661 cgaggaagga aagtatccaa ggcatctagg actgtgacct tgcttccaag tttgttgtaa
    27721 aggccggcaa attcaagacc gatatttccg ccaccaagga ttccaagttt ttcaggtaat
    27781 ttgtccaagt tttggatacc tgttgagtca aagatgtttt tgcttgtagc aagtccaggg
    27841 attggcaaga cgtttgaaac agcaccagtg ttgatgacga ttgtttcagc agtcagttct
    27901 ttcttttcat caccagcttg gatttcgatg actttatttg aaaggaagtg agcttccgca
    27961 tcaaagatat ctacgcctgt accagcaaca gtcgcatagt ttttaccgtt gaggcgacca
    28021 gtgatcgtgt ttttagtagc aatcacttct tcaaaagaca agtccttttc agcagcaact
    28081 agcaaggttt tagttgggat acaaccaatg ttgatacaag ttccaccgta catagccttg
    28141 ctgcgttcaa cgagggcaac ttttttgcca gctgaagcca atttacctgc tagtgtttta
    28201 ccagctttac caaatccaat aacaattaaa tcgtatgtta acatttatct tcctcctatt
    28261 cgaatttcat tctagcacaa gaaaaaaact tttgcacaat tctgctacgg aaaagacaga
    28321 aaaagataaa aacgctttcc agacaaaaaa ctagtaattt tttgacaagc ttgataaact
    28381 aaaatcctat ctatttttat ataagataga ataaatgttc gaaaatagga ggttttatga
    28441 aatcgaatcg ttatattatt gcctttgctg gggtcatttt acacttaatg ctgggttcga
    28501 cttatgcttg gagtgtttat cgtaacccta ttattgaaaa aacgggatgg gatcaggctt
    28561 ctgttgcctt tgcctttagt ctagcaatct tttgtttggg cttatcggct gcatttatgg
    28621 ggcgtttggt agaaaaattt ggtccgagag tcatggggag tctatctgct tttctatacg
    28681 caggtggaaa tatcttaaca ggatttgcaa tagaccgtca ggaactgtgg ttgttgtatc
    28741 tagcttatgg cattttaggt gggcttggtt tgggagcagg ctatattacc cctgtgtcaa
    28801 cgattataaa atggtttcct gataaacgtg gtctcgcaac aggtttagcg attatggggt
    28861 ttggttttgc ttctttattg actagtccca tagcgcaaca tctcatcgca ggggtagggc
    28921 ttgtagaaac tttttatatt ttaggtgcaa gttactttat tatcatgctc ctagcttcac
    28981 aattcattaa gcgtccaaat gagcaagagc ttgcaatttt atctgcttca gggaaagaaa
    29041 aaacagactc tctgacgcaa gggatgactg caaatcaggc tctaaaaagc aatcggtttt
    29101 atatactttg gattattttc tttatcaaca tagcttgtgg tttaggctta atttcagcgg
    29161 catcgccaat ggcacaggag atggctggct tgtctacaag tcatgcagca gtaatggtgg
    29221 gcgttttagg gattttcaat ggatttggtc gcttgctctg ggcgagctta tctgactata
    29281 tcggtcgccc tctaaccttt agtatattac tgcttgttaa tcttttcttt tctctctcac
    29341 tttggctctt tacagattcc gttttatttg tagtcgctat gtctattttg atgacttgct
    29401 atggagctgg tttttcattg atcccagctt atctcagtga tatttttgga accaaggaat
    29461 tggccgctct gcatggatat attttaacag cttgggcaat ggctggttta gcgggaccta
    29521 ttttattagc agagacttat aaaatggctc attcgtacac acaaaccttg ttcgtttttc
    29581 tcattttata cagtatcgcc ttggctttgt cttattatct aggtcgttca atcaaaaaag
    29641 aaagtcaaaa accgcttaca tgattttctg tagaaatggg gctatctttt gctctggtct
    29701 tgtgttatac tagataggtt gcaaagaaaa cagtactttt cttttgtgga aaagaagcaa
    29761 cacgatttta tatctagtta tatgaaaata cgtcataaaa agaaaagtat aaactaagcc
    29821 ctatagggtg gcttcgcacc acctttagaa agaagaataa cgtgaaattt aatgaattaa
    29881 acttgtctgc tgatttgcta gcagaaattg aaaaagctgg ttttgtagaa gctagtccta
    29941 tccaagaaca aactattcct ttggcccttg aaggcaagga tgttatcggt caagctcaga
    30001 ctggtacagg aaaaactgca gcctttggct tgcctaccct tgaaaaaatc cgtacagaag
    30061 aagcgactat ccaagctttg gtcatcgctc caactcgtga actagctgtc caaagtcaag
    30121 aagaactctt ccgctttggt cgtagtaagg gagtcaaagt ccgttcagta tatggcggat
    30181 caagcattga aaaacaaatt aaggctctta aatctggtgc ccatatcgtg gtgggaactc
    30241 caggtcgcct cttggacttg attaaacgca aggccttgaa attacaagac attgaaaccc
    30301 ttatccttga cgaagcggat gaaatgctta acatgggctt ccttgaagac atcgaagcca
    30361 ttatttcccg tgtacctgag aaccgtcaaa ctttgctttt ctcagcaact atgccagatg
    30421 ccatcaaacg tatcggtgtt cagtttatga aagcccctga acatgtcaag attgcggcta
    30481 aggaattgac aacagaattg gttgaccagt actatatccg tgttaaggaa caagaaaaat
    30541 ttgacaccat gactcgtctc atggatgtgg cacaaccaga actcgctatt gtatttggtc
    30601 gtaccaaacg ccgtgtggat gaattgactc gtggtttgaa aattcgtggc ttccgtgcag
    30661 aaggaattca tggcgaccta gaccaaaaca aacgtcttcg tgtccttcgt gactttaaaa
    30721 atggcaatct tgatgttttg gttgcgacag acgttgcagc gcgtggtttg gatatttcag
    30781 gtgtgaccca tgtctacaac tacgatattc cacaagatcc tgagagttat gttcaccgta
    30841 tcggtcgtac aggtcgtgct ggtaagtcag gtcaatctat tacttttgtt gctccaaacg
    30901 aaatgggtta ccttcaaatc attgaaaact tgactaagaa acgcatgaaa ggtctcaaac
    30961 ctgcaagtgt agaagaatcc ttccaatcaa aaaaacaggt agctctcaag aaaatcgaac
    31021 gtgattttgc agatgaaacc attcgtgcca actttgagaa atttggtaag gatgctcgca
    31081 aattggctgc tgagtttact ccagaagaat tggcaatgta tatcttgagt ctgacagtcc
    31141 aagacccaga tagccttcca gaagtggaga ttgcacgtga aaaaccacta ccgtttaaac
    31201 catcaggtaa tggtttcggt ggtaaagcta agggaggtcg tggaggccgt cgtggggatg
    31261 accgtcgaga gcgtgatcgc cgtggcaatg gtcgccgtga tgagttcaaa aaaggaagtc
    31321 gtggcaacga tcgttttgat aaggaaaaac gttaccgtaa ggataataaa aaaccacgca
    31381 atactttaaa cgaaaagcaa acaggctttg ttattcgtaa caaaggtgat aaataagaaa
    31441 aagcggttca aaatgaatcg cttttttata taaggagacc gaatgtgaaa aagacaaata
    31501 aaattattat attatctttt ataatattat gatacaaaaa aataggcaac ttgtcaatag
    31561 aaaaggaaca atttaattaa aaatattctg gtttttaatt aaattgtaag tcaatgcaag
    31621 tcaataagga attttcagat aattattgaa aaagagacgt ttttatgtta taatgatagc
    31681 gattaaattc gaggtgaaaa atggcacatt tattagaaaa aactagaaaa attacatcaa
    31741 ttttgaaacg ctcagaggag cagttgcagg atgagcttcc ttacaacgct attacgcgtc
    31801 agttagcgga tattattcat tgcaatgcct gcattatcaa tagtaaggga cgtctgcttg
    31861 gctattttat gcgttataaa acaaatacag atcgcgtaga gcaattcttc caaactaaga
    31921 ttttcccaga tgactacgtt caaggggcta atatgattta cgaaacagaa gcaaacttac
    31981 ctgttgagca tgatatgagt attttccctg ttgagagtag agatgatttt ccagatggct
    32041 tgacgactat tgcaccgatt catgtatcgg ggattcgcct tggttctttg attatttggc
    32101 gtaatgataa aaaattcgaa gatgaggact tggttcttgt tgagattgcc agtaccgttg
    32161 ttgggattca gcttcttaac ttccaacgtg aagaagatga gaaaaatatt cgtcgtcgta
    32221 ctgctgtcac catggcggtc aatacccttt cttactccga actccgtgct gtttcagcaa
    32281 ttttagggga attaaatgga aatgaaggga agttgactgc gtcagtgatt gcagatcgta
    32341 tcggaatcac tcgctctgtg attgtcaatg ctcttcgtaa acttgagtct gcggggatta
    32401 ttgaaagtcg ctcacttgga atgaagggaa cctatcttaa ggtcttgatt tcagatattt
    32461 ttgaagaagt gaagaaaaga gattactaat gacaaaggct ttaatttcga ttgattatac
    32521 agaagatttt gttgctgata gtgggaaact aacagcaggt gctccagctc aggcgatttc
    32581 ggatgccatc agcaaggtaa ctcgattagc ttttgaacga ggagattata tcttctttac
    32641 tattgatgct catgaagaaa acgattgttt ccatccggaa agtaagttat ttcctcctca
    32701 taatctgatt gggacgagtg gacggaattt atatggagat ttggggatct tttatcaaga
    32761 gcatggttca gacagtcgtg tcttttggat ggataaacgc cattactcag ctttttcagg
    32821 gactgaccta gatattcgtt tgagagagcg tagagtgtct accgttatct taacaggtgt
    32881 cttgacggat atctgtgtcc tacatacagc tatagatgcc tataatctag gatatgacat
    32941 cgagattgtt aaaccagctg ttgcttccat ctggcctgaa aatcatcaat ttgccctagg
    33001 tcatttcaaa aatacactcg gagctaagtt agtagatgaa aatctaaatg aactttctga
    33061 gtaacctggt tggtgaaaat gaaaaaattt gaaaaaaagt gttgacaagc atcccaaaag
    33121 ttgatatact agtaaagtaa tcgacgcggg gatggcggaa ttggcagacg cgcaggacta
    33181 aggatcctgt gaccgcttta ggtcgtgagg gttcaagtcc ctctctccgc ataggaaaag
    33241 agctagctaa agctagctct tttgtatttc tctaaaaaat tagaatccag tcaaatgtag
    33301 tggagaatca gcgaaaatat gggaaaactg atccttgttt ctgcttttgt ctatagaaga
    33361 ataataaaga ttatcttctt caaattctcc gatattctct aaagttttgt gcaagttgca
    33421 cagaactttt ttattttttt ggtcatcttg ccatagaaat ataaagcgtt ttcatctata
    33481 atataattat caaaagacaa aaggagttca cctcatggta gaattgaatc ttaaaaatat
    33541 ttacaaaaaa tatccaaaca gcgaacacta ttcagttgaa gatttcaact tgaacatcaa
    33601 agataaagaa tttatcgttt tcgtaggacc ttcaggatgt ggtaaatcaa ctacactccg
    33661 tatgattgct ggtcttgaag acattacaga aggtactgca tctatcgatg gcgtggttgt
    33721 caacgacgta gctccaaaag accgtgatat cgccatggta ttccaaaact acgctcttta
    33781 cccacacatg actgtttatg acaacatggc tttcggtttg aaattgcgta aatacagcaa
    33841 agaagacatt aacaaacgtg ttcaagaagc agctgaaata cttggattga aagaattctt
    33901 ggaacgtaaa ccagctgacc tttcaggtgg tcaacgtcaa cgtgttgcca tggggcgtgc
    33961 gattgtccgt gatgcgaaag tattcttgat ggacgaacct ttgtcaaact tggatgccaa
    34021 acttcgtgta tcaatgcgtg ctgaaatcgc taaaattcac cgtcgtatcg gagctacaac
    34081 tatctatgta actcacgacc aaacagaagc gatgacactt gcagaccgta tcgttattat
    34141 gtcagctact aagaaccctg ctggtacagg tactatcgga cgtgtagaac aaatcggtac
    34201 tcctcaagaa gtttacaaaa atccagttaa caaattcgtt gcaggattca tcggaagccc
    34261 agctatgaac ttcatcaacg tgaaattggt tggtagcgaa attgtttctg acggtttccg
    34321 tttgaaagtg ccagaaggag cattgaaagt tcttcgtgaa aaaggctacg aaggaaaaga
    34381 attgatcttt ggtatccgtc cagaagacgt gaatgcagaa cctgctttcc ttgaaacatt
    34441 cccagactgt gttgtaaaag cgactatctc tgtatcagaa ctgcttggtt cagaatctca
    34501 cctttactgc caagttggta aagacgagtt tgttgcaaaa gttgatgctc gtgactactt
    34561 gcaaacaggt gcaacagttg agcttggatt tgacttgaac aaagcacact tcttcgatgt
    34621 agaaactgaa aaaacaatct actaaaataa ataaaattca aagcactaca agaaaagata
    34681 tctctttatc aattgtagtg gagagatatc agttaatcta gggagagaaa caaaatgctt
    34741 ctctcctttt tgctagggaa gtcatattat gcatctatat tgtgatgctc tttaatactc
    34801 ttcgaaaatc tcttcaaacc acgtcaacgt cgccttgccg tacgtatgat tactgacttc
    34861 gtcagtttta tctgcaacct caaagctgta ctttgagcag cttacggcta gttttctagt
    34921 tttctctttg atttccattg agtattattt gtgggtacca tctacaagtg aagctatatg
    34981 cgtaaactac gtgagcaatt gaattcgaac tagagaggta ataataaatt tatgctatag
    35041 ttatggtgac ttgtatgctt ttgattctag tttatcaaat aatagattag aattgtcaga
    35101 taatatcatt ttgtgttata atgaagaaaa aacagaggtg ttcaaatgtc agaagcaggt
    35161 cataagtttt tagcaaaatt ggggaaaaaa cgcttacgtc caggtggaaa gcgtgccaca
    35221 gattggttaa ttgcagaagg aggattttca aaagaaaaga gaatactaga ggttgcgtgt
    35281 aataggggaa ctacagcaat tgagttggca cagcgttttg gttgcaagat aactgctatt
    35341 gatatggatg ctcaagcttt agaagtggct aaaaaatctg ctggaacggc aggtgttgct
    35401 catttaatca gttttgaaag agcaaatgca atgaaacttc cttatcaaga tgctagtttt
    35461 gatattgtta taaatgaagc tatgctgact atgcaagccg atcaagctaa gaaaaaatgt
    35521 gtaatggaat atctaagggt attaaaacct ggaggtcttc tcttgacaca tgatgtgctt
    35581 cttaaggaag ctaaagagtc tatcagacag gaattatcac aagcaattca tgtaaatgta
    35641 ggtcctttaa ctcaagatgg ttgggaacag gtgatgatag aatcaggtta ttgtgatgtg
    35701 aaagcattga ctggtgaaat gacattaatg aaattatcgg gtatgattta tgacgaaggt
    35761 ttgctaggaa ctttgaaaat ttgtgtaaat gcttgtaaaa aggagaatag aaagcagttt
    35821 ttaactatgt ataaaatgtt tgctaagaat aaacagaaat tgggctttat tgcgatggct
    35881 agttataaat cgtcaaaacg ttagataatt attgaagtta acttttcctt ttttctttct
    35941 taaaaaatat gctataatag agagtaaaaa actttgaaag aaagaaaaag atgaatttaa
    36001 aagattacat tgcaacaatt gaaaattatc caaaggaagg cattaccttc cgtgatatta
    36061 gtcctttgat ggctgatgga aatgcttata gctacgctgt tcgtgaaatc gttcagtatg
    36121 ctactgacaa gaaagtcgac atgatcgtgg gacctgaagc tcgtggattt atcgtgggtt
    36181 gtccagttgc ctttgagttg ggaattggtt ttgcgcctgt tcgtaagcca ggtaaattgc
    36241 cacgcgaagt tatttctgct gactatgaaa aagagtacgg tgtcgatacc ttgactatgc
    36301 acgcggatgc cattaagcca ggtcaacgtg ttcttattgt agatgacctt ttggcgacag
    36361 gtggaactgt taaggcaact atcgagatga ttgaaaaact tggtggtgtt atggcaggtt
    36421 gtgccttcct tgttgaattg gatgaattga acggccgtga aaaaattggt gactacgact
    36481 acaaagttct tatgcattat taatgaaaac agtccctagg gctgttttct ctacactagg
    36541 atataaaaat agactataac tagttagaga aaaactataa ttgaaaacta tatcttctta
    36601 cagtataata aaaggactaa gtgtttgaga tttgtcttca aacatatgca attattcctg
    36661 aaagagtaca gttaggagag ggttatgccg attcgaattg ataaaaaatt gccagctgtt
    36721 gagattttac ggacagagaa tatctttgtc atggatgatc aacgtgctgc ccaccaagat
    36781 atccgtcctt tgaagatttt aattttaaat ctcatgccac agaaaatggt cacagagacc
    36841 cagttgttgc gccacttggc taatacaccc ctacaactgg atattgattt tctctatatg
    36901 gagagccacc gttctaaaac aactcgttca gagcacatgg agaccttcta taaaactttt
    36961 cctgaagtca aggatgagta ttttgatggg atgatcatca cgggtgctcc agttgagcat
    37021 ttaccatttg aggaagtgga ctattgggag gaatttagac agatgcttga gtggtctaag
    37081 actcatgtct attcgaccct tcatatctgt tggggggctc aggctgggct ttatctgcgc
    37141 tatggtgtag aaaaatacca gatggacagt aagctatcag gtatttatcc tcaggacacc
    37201 ctaaaagagg gtcaccttct atttagaggc tttgatgata gctatgtatc ccctcattca
    37261 cggcacacgg agatttctaa ggaagaggtc ttaaacaaga ccaatctcga gattttatca
    37321 gaaggacctc aggttggggt ttctattttg gccagtcgtg atttacgaga aatttatagt
    37381 tttggtcatt tggagtatga ccgtgatacc ttggcaaaag agtattttcg agatcgtgat
    37441 gcaggtttcg acccacatat tccagaaaat tactttaaag atgatgatgt taatcaggta
    37501 ccttgtcttt gttggtcttc atctgcagcc ctctttttca gtaattgggt aaaccatgcg
    37561 gtctatcagg agacgccttt tgattggaga aagatagaag atgatgcatc tgcatatggg
    37621 tatttataag aggaattatg acatatttag acgcttttaa atcaggtacc ttggttttac
    37681 cgagtgccct gctcttgcat tttaaggaac tctttccttc tagcgacgat tttctggttt
    37741 ggcaattttt ctatttgcaa aatacgacag gcttagaaga aatgtcgcca agccagattg
    37801 ctgaaaggat tggcaaggaa atttcggatg tcaaccagtc catttctaat ctgacggaaa
    37861 ggggactgct ccagtatcgt actatcgaat taaatggcga aattgaattg ttctttgatg
    37921 ctagtttggc cttggaacgt ttggatgacc tgtttggagc agttcgttca agttcagacc
    37981 agctaacacc tcaaaaccag ctcaaggatt tggtggaaac cttccagcag gagttgggac
    38041 gattgttgac gccttttgag attgaggatt tgaccaagac actaaaggaa gatggaacca
    38101 gtgctgactt gattaaggag gctcttcgtg aagctgtttt gaatggaaaa ccaaactgga
    38161 agtacattca ggcaattttg agaaactggc gccatgaagg aatcaagagt gtggctcaaa
    38221 ttgaggccaa gagagcagaa agagaagcaa gcaatcctca gttgacacag gtatctgcag
    38281 atttcagaaa tgccatggat ctctggaagg attaatccat gcaagtaggc ttgaaatccg
    38341 agtaagattt gcaagctgtg tataattgtg atagaataaa tagaaaataa attgaaaaaa
    38401 gaggtatgtg aaatgtcacg taaaccattt atcgctggta actggaaaat gaacaaaaat
    38461 ccagaagaag ctaaagcatt cgttgaagca gttgcatcaa aacttccttc atcagatctt
    38521 gttgaagcag gtatcgctgc tccagctctt gatttgacaa ctgttcttgc tgttgcaaaa
    38581 ggctcgaacc ttaaagttgc tgctcaaaac tgctactttg aaaatgcagg tgctttcact
    38641 ggtgaaacta gcccacaagt tttgaaagaa atcggtactg attacgttgt tatcggtcac
    38701 tcagaacgcc gtgactactt ccatgaaact gacgaagata tcaacaaaaa agcaaaagca
    38761 atctttgcga acggtatgct tccaatcatc tgttgtggtg aatcacttga aacttacgaa
    38821 gctggtaaag ctgctgaatt cgtaggtgct caagtatctg ctgcattggc tggattgact
    38881 gctgaacaag ttgctgcctc agttatcgct tatgagccaa tctgggctat cggtactggt
    38941 aaatcagctt cacaagacga tgcacaaaaa atgtgtaaag ttgttcgtga cgttgtagct
    39001 gctgactttg gtcaagaagt cgcagacaaa gttcgtgttc aatacggtgg ttctgttaaa
    39061 cctgaaaatg ttgcttcata catggcttgc ccagacgttg acggtgccct tgtaggtggt
    39121 gcgtcacttg aagctgaaag cttcttggct ttgcttgact ttgtaaaata atcagtaagt
    39181 agcaaaagct aggtggaaca gcattcagat gtctgttaca ttttttatag gagaggaaag
    39241 attgaaaata aaaattggat tagcaagtat ctgtttacta ggcttggcaa ctagtcatgt
    39301 cgctgcaaat gaaactgaag tagcaaaaac ttcgcaggat acaacgacag cttcaagtag
    39361 ttcagagcaa aatcagtctt ctaataaaac gcaaacgagc gcagaagtac agactaatgc
    39421 tgctgcccac tgggatgggg attattatgt aaaggatgat ggttctaaag ctcaaagtga
    39481 atggattttt gacaactact ataaggcttg gttttatatt aattcagatg gtcgttactc
    39541 gcagaatgaa tggcatggaa attactacct gaaatcaggt ggatatatgg cccaaaacga
    39601 gtggatctat gacagtaatt acaagagttg gttttatctc aagtcagatg gggcttatgc
    39661 tcatcaagaa tggcaattga ttggaaataa gtggtactac ttcaagaagt ggggttacat
    39721 ggctaaaagc caatggcaag gaagttattt cttgaatggt caaggagcta tgatgcaaaa
    39781 tgaatggctc tatgatccag cttattctgc ttatttttat ctaaaatccg atggaactta
    39841 tgctaaccaa gagtggcaaa aagtgggtgg caaatggtac tatttcaaga agtggggcta
    39901 tatggctcgg aatgagtggc aaggcaacta ctatttgact ggaagtggtg ccatggcgac
    39961 tgacgaagtg attatggatg gtgctcgcta tatctttgcg gcttctggtg agctcaaaga
    40021 aaagaaagat ttgaatgtcg gctgggttca cagagatggt aaacgctatt tctttaataa
    40081 tagagaagaa caagtgggaa ccgaacatgc taagaaaatc attgatatta gtgagcacaa
    40141 tggtcgtatc aatgattgga aaaaggttat tgatgagaac gaggtggatg gtgtcattgt
    40201 tcgtctaggt tatagcggta aagaagacaa ggaattggcg cataacatta aggagttaaa
    40261 ccgtctggga attccttatg gtgtctatct ctatacctat gctgaaaatg agaccgatgc
    40321 tgagaatgac gctaaacaga ccattgaact tataaagaaa tacaatatga acctgtctta
    40381 ccctatctat tatgatgttg agaactggga atatgtaaat aagagcaaga gagctccaag
    40441 tgatacagac acttgggtta aaatcatcaa caagtacatg gacacgatga agcaggcggg
    40501 ttatcaaaat gtgtatgtct atagctatcg tagtttatta cagacgcgtt taaaacaccc
    40561 agatatttta aaacatgtaa actgggtagc ggcctatacg aatgctttag aatgggaaaa
    40621 cccttattat tcaggagaaa aaggttggca atatacctct tctgaataca tgaaaggaat
    40681 ccaagggcgc gtagatgtca gcgtttggta ttaagcgatg atttgaaaga gggatgtgat
    40741 agtagcaccc tctttttctt tgtttta
//
LOCUS       DAVLMQ010000014        39874 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000014 DAVLMQ010000000
VERSION     DAVLMQ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.014"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            654..2807
                     /locus_tag="VXF95_000885"
     CDS             654..2807
                     /locus_tag="VXF95_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HEV1081457.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPHKDQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTLINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAALSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            2820..4169
                     /locus_tag="VXF95_000886"
     CDS             2820..4169
                     /locus_tag="VXF95_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HEV1081458.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTVKSAIETGASLAGQNLAYSLYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAEINLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            4339..5046
                     /locus_tag="VXF95_000887"
     CDS             4339..5046
                     /locus_tag="VXF95_000887"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HEV1081459.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            5248..8973
                     /locus_tag="VXF95_000888"
     CDS             5248..8973
                     /locus_tag="VXF95_000888"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HEV1081460.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDATELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDTFVA
                     ECNKENIDAVVVATVTEKPNLVMHWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTIFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNPYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLA
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFTQFEAIQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKVG
                     QTKADFTLTVNRVKLDGHKLDSAFQGTLEEVYPTEFTRAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEAANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            9066..10508
                     /locus_tag="VXF95_000889"
     CDS             9066..10508
                     /locus_tag="VXF95_000889"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HEV1081461.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPANLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            10545..11567
                     /locus_tag="VXF95_000890"
     CDS             10545..11567
                     /locus_tag="VXF95_000890"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HEV1081462.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTERAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            11564..12109
                     /gene="purN"
                     /locus_tag="VXF95_000891"
     CDS             11564..12109
                     /gene="purN"
                     /locus_tag="VXF95_000891"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HEV1081463.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYMKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYPEVVKALFTD"
     gene            12193..12702
                     /locus_tag="VXF95_000892"
     CDS             12193..12702
                     /locus_tag="VXF95_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HEV1081464.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLIFFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITNLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            12727..14274
                     /gene="purH"
                     /locus_tag="VXF95_000893"
     CDS             12727..14274
                     /gene="purH"
                     /locus_tag="VXF95_000893"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HEV1081465.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAEYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWDYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            14396..15658
                     /gene="purD"
                     /locus_tag="VXF95_000894"
     CDS             14396..15658
                     /gene="purD"
                     /locus_tag="VXF95_000894"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HEV1081466.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVPTAIYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGVIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQLILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            16061..16549
                     /gene="purE"
                     /locus_tag="VXF95_000895"
     CDS             16061..16549
                     /gene="purE"
                     /locus_tag="VXF95_000895"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HEV1081467.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTTLPVIGVPVKSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDKSIADALANFAEEQGKIAEESSNE
                     LI"
     gene            16536..17627
                     /gene="purK"
                     /locus_tag="VXF95_000896"
     CDS             16536..17627
                     /gene="purK"
                     /locus_tag="VXF95_000896"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HEV1081468.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDAVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKTATGGYDGHGQKVIRSEAD
                     LEAAYALADSADCVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATDDDVIVNEIAPRPHNSGHYSIETC
                     DFSQFDTHILGVLGAPLPVIKLHAPAVMLNVLGQHVEAAEQYVTENSSAHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            17637..17864
                     /locus_tag="VXF95_000897"
     CDS             17637..17864
                     /locus_tag="VXF95_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HEV1081469.1"
                     /translation="MIQIIVNTFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIEKEEFE"
     gene            17927..19225
                     /gene="purB"
                     /locus_tag="VXF95_000898"
     CDS             17927..19225
                     /gene="purB"
                     /locus_tag="VXF95_000898"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HEV1081470.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(19280..23218)
                     /gene="strH"
                     /locus_tag="VXF95_000899"
     CDS             complement(19280..23218)
                     /gene="strH"
                     /locus_tag="VXF95_000899"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HEV1081471.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTTEN
                     QPTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEV
                     SSTPSDKAEVVTPTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDE
                     AKAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTD
                     LHLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTD
                     LINYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAV
                     AFTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYE
                     KFIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVAS
                     SKLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIP
                     IIGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRY
                     TAESVAAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEAQKEEEAKR
                     EVEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLNDMTI
                     TANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSP
                     GHMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMDFVKALIGKYMDFFAGKTKI
                     FNFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYE
                     DKDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYVIGNHKQEEAY
                     PLSKAVENSGKVPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFA
                     DHNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTL
                     VANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAG
                     QENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESG
                     LAPTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADG
                     KEVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPA
                     EESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(23534..24250)
                     /locus_tag="VXF95_000900"
     CDS             complement(23534..24250)
                     /locus_tag="VXF95_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1081472.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            24598..26385
                     /locus_tag="VXF95_000901"
     CDS             24598..26385
                     /locus_tag="VXF95_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HEV1081473.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFKTLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            26382..26858
                     /locus_tag="VXF95_000902"
     CDS             26382..26858
                     /locus_tag="VXF95_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1081474.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            26886..27791
                     /locus_tag="VXF95_000903"
     CDS             26886..27791
                     /locus_tag="VXF95_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1081475.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            27778..28593
                     /locus_tag="VXF95_000904"
     CDS             27778..28593
                     /locus_tag="VXF95_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1081476.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            28600..29004
                     /locus_tag="VXF95_000905"
     CDS             28600..29004
                     /locus_tag="VXF95_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081477.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            29298..30464
                     /locus_tag="VXF95_000906"
     CDS             29298..30464
                     /locus_tag="VXF95_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HEV1081478.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVAKPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVMITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            30580..31617
                     /locus_tag="VXF95_000907"
     CDS             30580..31617
                     /locus_tag="VXF95_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HEV1081479.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHIYNGTLLKDIFAEEDEQIQLASGLDHPFALPVGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            31815..32669
                     /locus_tag="VXF95_000908"
     CDS             31815..32669
                     /locus_tag="VXF95_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1081480.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGEKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSKLEITDSDGI
                     VTRIRLAR"
     gene            32819..33059
                     /locus_tag="VXF95_000909"
                     /pseudo
     CDS             32819..33059
                     /locus_tag="VXF95_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
     gene            complement(33390..33482)
                     /locus_tag="VXF95_000910"
                     /pseudo
     CDS             complement(33390..33482)
                     /locus_tag="VXF95_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(33518..33814)
                     /locus_tag="VXF95_000911"
     CDS             complement(33518..33814)
                     /locus_tag="VXF95_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1081481.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPGAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLISQGLTVTNVEGGMNAWPGQVE"
     gene            complement(33804..33965)
                     /locus_tag="VXF95_000912"
     CDS             complement(33804..33965)
                     /locus_tag="VXF95_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(FAD)-dependent dehydrogenase"
                     /protein_id="HEV1081482.1"
                     /translation="MDKKQAYIVSCHSGLRSYIAEPILKQAGFTAQNLDGAYSLYKMV
                     NPEGVEYGN"
     gene            34035..34799
                     /locus_tag="VXF95_000913"
     CDS             34035..34799
                     /locus_tag="VXF95_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HEV1081483.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVINYKGEEVCLAQAPVGSAPAAQFMDWLVGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIEEVLE
                     DRGIPYEEVMTWTTDGFYRETAEKVAYRKEEGCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLDQYDSRDWGSEAFNKALELSLASVHHL"
     gene            complement(35039..35191)
                     /locus_tag="VXF95_000914"
     CDS             complement(35039..35191)
                     /locus_tag="VXF95_000914"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081484.1"
                     /translation="MRTKASLRKLVTGCSKHCFEVVDRTDEVSSKHCFEVADRTDEVS
                     NIYTAR"
     gene            35409..36788
                     /locus_tag="VXF95_000915"
     CDS             35409..36788
                     /locus_tag="VXF95_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1081485.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRLIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
     gene            36802..37467
                     /locus_tag="VXF95_000916"
     CDS             36802..37467
                     /locus_tag="VXF95_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HEV1081486.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            37597..37677
                     /locus_tag="VXF95_000917"
                     /pseudo
     CDS             37597..37677
                     /locus_tag="VXF95_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            37823..38272
                     /locus_tag="VXF95_000918"
     CDS             37823..38272
                     /locus_tag="VXF95_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1081487.1"
                     /translation="MKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQT
                     QEIAECLASKYPNIVRAIYQENKGHGGVVNCGLAEASGRYFKVVDSDDWVDPRAYLKI
                     LETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD"
     gene            38429..38839
                     /locus_tag="VXF95_000919"
     CDS             38429..38839
                     /locus_tag="VXF95_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HEV1081488.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKRIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSETAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            38955..>39874
                     /gene="pavB"
                     /locus_tag="VXF95_000920"
     CDS             38955..>39874
                     /gene="pavB"
                     /locus_tag="VXF95_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HEV1081489.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRSNGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVEKAVK"
BASE COUNT        11005 a         7755 c         9309 g        11805 t
ORIGIN      
        1 ttaattagaa aaaaattttt aaagtcttcg gagaagaaaa cagaaaaatc tgttaaaaaa
       61 taatcaaaac tataaatgat gaatctgaat caaaattatt ttgcgcatgt aaagaggagt
      121 cttgcagtaa cgaatcaaaa aaaaggagta actatgaatc gtaatttaga atggtgttat
      181 ctattatgac tataaataga tcataccaga ggtggcttag aaatagcagg gacattagaa
      241 attgaagtaa ctttaaatag gatgtcgtaa atgttgctat caatgattta tttgtcccaa
      301 gcttgcctag ggtgtcagta aaaaatcatt ttcctttcat accatatttt tagtaggtag
      361 aacgtttgtt ctgcctattt ttttatccaa aaagtgcagt tgggagggag ataggctcat
      421 ttgggaagga agtccagttt ttgtttagtg attggggtaa gatagttgtt atcagatgag
      481 tttatactct tcgaaaatca aattcaaacc acgtcaacgt cgccttgccg tatatatgtg
      541 actgacttcg tcagtcctat ctacaacctc aaaacagtgt tttgagcagc ctgcggctag
      601 tttcctagtt tgctctttga ttttcattga gtattaggga aaaggagatg aatatgaaat
      661 ttgggaaacg tcactatcgt ccgcaagtgg atcagatgga ctgcggtgta gcttcattag
      721 ccatggtttt tggctactat ggtagttatt attttttggc tcacttgcga gaattggcta
      781 agacgaccat ggatgggacg acggctttgg gcttggtcaa ggtggcagag gagattggct
      841 ttgagacacg agctatcaag gcggatatga cgctttttga tttgcccgat ttgacttttc
      901 cttttgttgc ccatgtgctt aaggaaggga aattgctcca ctactatgtg gtgactgggc
      961 aggataagga cagcattcat attgccgatc cagatcctgg ggtgaaattg accaaactgc
     1021 cacgtgagcg ttttgaggaa gaatggacag gagtgactct gtttatggca cctagtccag
     1081 actacaagcc tcataaggat caaaagaatg gtctgctctc ttttatccct atattagtga
     1141 agcagcgtgg cttgattgcc aatatcgttt tggcaacact cttggtaacc ttgattaaca
     1201 ttgtgggttc ttattatctg cagtctatca ttgataccta tgtgccagat cagatgcgtt
     1261 cgacgttggg gattatttct attgggctag tcatcgtcta catcctccag caaatcttgt
     1321 cttacgctca ggagtatctc ttgcttgttt tggggcaacg cttgtcgatt gacgtgattt
     1381 tgtcctatat caagcatgtt tttcacctcc ctatgtcctt ctttgcgaca cgcaggacag
     1441 gggagatcgt gtctcgtttt acagatgcta acagtatcat cgatgcgctg gcttcgacca
     1501 tcctttcgat tttcctagat gtgtcaacgg ttgtcattat ttcccttgtt ttattttcac
     1561 aaaataccaa tctctttttc atgactttat tggcgcttcc tatctacaca gtgattatct
     1621 ttgcctttat gaagccattt gaaaagatga atcgggacac catggaagcc aatgcggctc
     1681 tgtcttcttc tatcattgag gacatcaatg gtattgagac tatcaagtcc ttgaccagtg
     1741 aaagtcagcg ttaccaaaaa attgacaagg aatttgtgga ttatctgaag aaatccttta
     1801 cctatagtcg agcagagagt cagcaaaagg ctctgaaaaa ggttgcccat ctcttgctta
     1861 atgtcggcat tctctggatg ggggctgttc tggtcatgga tggcaagatg agtttggggc
     1921 agttgattac ctataatacc ttgctggttt actttaccaa tcctttggaa aatatcatca
     1981 atctgcaaac caagcttcag acagcgcagg ttgccaataa ccgtctaaat gaagtgtatc
     2041 tagtagcttc tgagtttgag gagaagaaaa cagttgagga tttgagcttg atgaagggag
     2101 agatgacttt caagcaggtt cattacaagt atggctatgg tcgagacgtc ttgtcggata
     2161 tcaatttaac cgttccccaa gggtctaagg tggcttttgt ggggatttca gggtcaggta
     2221 agacgacttt ggccaagatg atggttaatt tttacgaccc aagtcaaggg gagattagtc
     2281 tgggtggtgt caatctcaat cagattgata aaaaagccct gcgccagtac atcaactatc
     2341 tgcctcaaca gccctatgtc tttaacggaa cgattttgga gaatcttctt ttgggagcca
     2401 aggaggggac gacacaggaa gatatcttac gggcggtcga attggcagag attcgagagg
     2461 atatcgagcg catgccactg aattatcaga cagaattgac ttcggatggg gcagggattt
     2521 caggtggtca acgtcagaga atcgctttgg cgcgtgctct cttgacagat gcgccggtct
     2581 tgattttgga tgaggcgact agcagtttgg atattttgac agagaagcgg attgtcgata
     2641 atctcatggc tttggacaag accttgattt tcattgctca ccgcttgact attgctgagc
     2701 ggacagagaa ggtagttgtc ttggatcagg gcaagattgt cgaagaagga aagcatgctg
     2761 atttgcttgc acagggtggc ttttacgccc atttggtcaa tagctagaaa gaggagagga
     2821 tgaaaccaga atttttagaa agtgcggagt tttataatcg tcgttaccat aatttttcca
     2881 gtagtgtgat tgtacccatg gcccttctgc tcgtgttttt acttggcttt gcaactgttg
     2941 cagaaaagga gatgagtttg tccactagag ctactgtcga acctagtcgt atccttgcaa
     3001 atatccagtc aactagcaac aatcgtattc ttgtcaatca tttggaagaa aataagctgg
     3061 ttaagaaggg ggatcttttg gttcaatacc aagaaggggc agagggtgtc caagcggagt
     3121 cctatgccag tcagttggac atgctaaagg atcaaaaaaa gcaattggag tatctgcaaa
     3181 agagcctgca agaaggggag aaccactttc cagaggagga taagtttggc taccaagcca
     3241 cctttcgcga ctacatcagt caagcaggca gtcttagggc tagtacatcg caacaaaatg
     3301 agaccatcgc gtcccagaat gcagcagcta gccaaaccca agccgaaatc ggcaacctca
     3361 tcagtcaaac agaggctaaa attcgcgatt accagacagt taagtcagct attgaaacag
     3421 gtgcttcctt ggccggtcag aatctagcct actctcttta ccagtcctac aagtctcagg
     3481 gcgaggaaaa tccccaaact aaggttcagg cagttgcaca ggttgaagca cagatttctc
     3541 agttagaatc tagtcttgct acttaccgtg tccagtatgc aggttcaggt acccagcaag
     3601 cctatgcgtc agggttaagc agtcaattgg aatcccttaa atcccaacac ttggcaaagg
     3661 ttggtcagga attgaccctt ctagcccaga aaatcttgga ggcagagtca ggtaagaagg
     3721 tacagggaaa tcttttagac aaggggaaaa ttacggcaag tgaggatggg gtgcttcatc
     3781 ttaatcctga gaccagtgat tctagcatgg ttgcagaagg tgccctacta gcccaacttt
     3841 atccatcttt ggaaagagaa gggaaagcca aactcacagc ctatctaagt tcaaaagatg
     3901 tagcaagaat caaggtcggt gattctgttc gctatactac gactcatgat gccgggaatc
     3961 aactttttct agattctact attacaagta ttgatgcgac agctactaag actgagaaag
     4021 ggaatttctt taaaatcgag gcggagatta atctaacttc ggagcaggct gaaaaactta
     4081 ggtacggggt ggaaggccgt ctacagatga ttacgggcaa gaaaagttat ctacgttatt
     4141 atttggatca atttttgaac aaagagtaat gttcgtgttt ttagagttaa ataattttta
     4201 aactgtgaga aagattcttc ttgcagtttt ttctttacaa tttttgaaaa acatctgcta
     4261 tttattcggt taaattcttg tgttttttgg ttttttgtgg taaaatgtgc tcaagtaata
     4321 cgaaaggcga actttaaaat gtcaaaacaa ttgatctatt cgggaaaagc taaagatatc
     4381 tatacaactg aggatgaaaa tcttattatt tcaacttaca aggaccaggc gactgctttc
     4441 aacggtgtca agaaggagca gattgcaggt aagggagtct tgaataatca gatctcatct
     4501 tttatttttg agaaattaaa tgcggctggt gtggcgactc actttgtgga gaaactttca
     4561 gacacggaac aactcaataa aaaggttaag attattcctt tggaagtcgt gctccgcaac
     4621 tatactgctg gttccttttc aaaacgtttt ggtgtggatg agggaatcgc cttggagact
     4681 ccgattgtcg aattttacta caaaaatgat gatttggatg atccatttat caatgatgag
     4741 catgtgaaat tcctacagat tgcggatgac cagcagattg cctacttgaa ggaagaaacg
     4801 cgtcgtatca atgaactatt gaaagtctgg tttgctgaga ttgggcttaa attgattgac
     4861 tttaagctag agttcggttt tgacaaggat ggcaagatta tcttggcaga cgaattttca
     4921 ccagataact gccgcttgtg ggatgctgat ggcaaccaca tggataagga tgttttccgt
     4981 agaggattgg gagaactaac cgacgtttat gagattgttt gggaaaagtt gcaggaattg
     5041 aaataatctg tttgcaatgg aaaaccttcg tctctcaact aaaaggactc aggctgaaaa
     5101 ggtcccccag accttttcac tctgtagaga actaggtgaa ccaaccgatg tttacgaaat
     5161 tgtctgggaa aagttgcagg gtttaaaata acaacctcaa ggctgtttgg gaatattgca
     5221 agagctgaaa taaaggaata agaattgatg gataaacgta tttttgttga aaaaaaggct
     5281 gattttcagg tcaagtcaga gagtttggtt agagagctcc agcacaactt gggactgtca
     5341 agcttgaaaa gtattcgtat tgtgcaagta tatgatgtat ttgacttggc tgaggacttg
     5401 tttgcacctg cagagaagca cattttctct gagcaggtaa ccgaccatgt tttagatgaa
     5461 gtatctgtgc aggcggatct tgctaactat gctttctttg ccattgaaag tctgccaggg
     5521 cagtttgacc agcgtgcagc ttcgtcacag gaagccttgc ttttgttggg aagttcgagt
     5581 gacgtgacag tcaacacagc ccaactttac ttggtgaata aagatattga tgcgactgag
     5641 ttggaagctg tcaaaaacta cctgctcaat ccagttgatt ctcgtttcaa ggatatcacg
     5701 acagggattg ccaagcagga gttttcagag tcagacaaga ccattccaaa attgactttc
     5761 tttgaaagct atacagcaga agactttgct cgctacaagg ccgaacaagg gatggccatg
     5821 gaagtggatg atttgctctt tatccaagac tactttaagt caatcgggcg cgtgccaact
     5881 gagactgaac ttaaggtttt ggacacttac tggtctgacc actgccgtca tacgactttt
     5941 gagacagagt tgaaacacat cgacttttca gcttctaaat ttcaaaagca attgcagtca
     6001 acctatgaca agtatattgc catgcgcgag gaattaggtc ggtctgaaaa accacaaacc
     6061 ttgatggata tggcgactat tttcggtcgt tatgagcgtg ctaatggacg attggatgat
     6121 atggaagtct ctgacgaaat caatgcctgc tcagttgaaa ttgaagtgga cgttgatggt
     6181 gtcaaggaac cttggctcct catgtttaaa aacgaaaccc acaaccatcc aacagaaatt
     6241 gagccatttg gtggagcggc tacctgtatt ggtggagcta ttcgtgatcc gttgtcaggc
     6301 cgttcctatg tttaccaagc catgcgtatt tcaggtgctg gtgatattac agcaccgatt
     6361 tcggaaactc gcgctgggaa attgccacaa caagtcattt ctaaaacagc agctcatggt
     6421 tattcttcat atggtaacca gattgggctt gcaacaacct acgttcgtga atacttccac
     6481 ccaggctttg tagctaaacg tatggaactt ggtgccgttg ttggtgcggc tcccaagggc
     6541 aatgttgtcc gtgaaaaacc tgaagcaggt gatgtgatca tccttctcgg aggcaaaaca
     6601 ggtcgtgatg gtgtcggtgg tgcgacgggc tcttctaagg ttcaaacagt tgagtctgta
     6661 gagactgctg gtgctgaggt tcaaaaagga aatgccatcg aagaacgcaa gattcagcgc
     6721 ctcttccgta atggcaatgt cactcgtctg atcaagaagt ccaatgactt tggggcaggc
     6781 ggtgtctgtg tggctatcgg tgaattggca gacggtcttg aaatcgacct caacaaggtg
     6841 cctcttaaat accagggctt gaatggtaca gaaattgcca tctctgaatc acaagaacgg
     6901 atggcggtcg tggttcgtcc tgaagatgtg gataccttcg ttgccgaatg taacaaagaa
     6961 aatattgatg ctgttgtggt ggcgacagta actgaaaaac caaatcttgt catgcactgg
     7021 aatggtgaga caatcgttga cttggagcgt cgtttccttg acaccaatgg tgtgcgcgtg
     7081 gttgtcgatg ccaaagttgt ggacaaggat gtcaaactcc cagaagagcg tcaaacatct
     7141 gctgaaacac tggaatcaga tacccttacg gttctatctg acctcaacca tgcaagtcaa
     7201 aaaggattac agactatctt tgactgctct gttggacgct caacggttaa tcacccactt
     7261 ggtggtcgtt accaactcac accaactgag gcatctgtgc agaaattgcc agttcaacac
     7321 ggtgtgactc atactgcgtc ggtcattgct caaggtttca acccatatgt agctgaatgg
     7381 tctccatacc acggtgctgc ttatgcggtt atcgaagcaa ctgctcgttt ggtggctgct
     7441 ggtgccaact ggtccaaggc tcgtttctct taccaagagt atttcgagcg gatggacaaa
     7501 caagcagagc gtttcggtca gccagtagcc gcccttctag gttctattga agcacaaatt
     7561 cagcttggct tgccatctat cggtggtaag gactccatgt ctggtacctt tgaagaattg
     7621 accgttccgc caaccttggc tgcctttggg gtgacgacgg cagatagccg taaggtgctc
     7681 tctccagaat ttaaagctgt tggggaaaat atctactaca tcccaggtca agccctctct
     7741 gcagagattg attttgactt gattaagaaa aattttactc agtttgaagc catccaagct
     7801 gaccataaag tgacatctgc atcagctgtc aaatacggtg gtgtagttga aagtttggct
     7861 cttgctacct ttggaaacta tattggtgca gaggtgacct tgcctgaact taaaacagct
     7921 ttgacagctc aattaggcgg ctttgtcttc acatctcctg aagaaattgc tggagtagag
     7981 aaggttggac aaacgaaagc agactttaca ctgactgtca accgtgtgaa actagatgga
     8041 cacaagcttg acagtgcatt tcaagggaca ttggaagaag tttacccaac agaatttacc
     8101 cgagcgaaag aactagaaga agtaccagct gtggcatcag atgttgtgat taaagccaaa
     8161 gaaaaggttg aaaaacctgt ggtttacatc ccagtctttc caggaaccaa ctcagaatat
     8221 gattcagcta aggccttcga aaaagaaggt gcagaggtca atttggtgcc attcgtgacc
     8281 ttgaatgaag aagctattgt caagtcagtt gaaactatgg ttgacaatat cgacaagact
     8341 aatattctct tctttgctgg tggattctcg gctgcggatg aaccagatgg ttcagctaag
     8401 tttatcgtca atatcctgct taatgaaaaa gtgcgtgtgg ctattgatag ctttatcgcc
     8461 cgtggtggtt tgattatcgg tatttgtaat ggattccaag ccttagtcaa atcgggtctc
     8521 ctaccctacg gaaactttga agctgctaac agtactagcc caaccctctt ctacaatgat
     8581 gccaaccaac acgtggccaa gatggtggaa actcgtattg ccaataccaa ctcaccatgg
     8641 ttggctggtg tgcaagtggg cgatatccac gctattcctg tttcgcacgg tgaagggaag
     8701 tttgtcgtga cggctgagga atttgcagag ctccgtgaca atggacaaat tttcagccaa
     8761 tacgttgact ttaacggtaa accaagtatg gattctaagt acaatccgaa tggttctgtc
     8821 catgccatcg aaggaattac cagcaagaat ggtcaaatca tcggtaagat gggccactca
     8881 gaacgttatg aggatggtct tttccaaaat atcccaggca ataaagacca acacctgttc
     8941 gcatcagcgg ttaaacattt cactggaaaa taagacttac agattttcta atagatagta
     9001 tcagtaatgt aaaagtcatg taaatctagc tcttgatgat tacaaatgaa aattaggtat
     9061 aaaaaatgac atacgaagta aaatctctta atgaagaatg tggtgttttc ggtatttggg
     9121 gacatccaga tgctgctaag ttgacctatt ttggactcca cagtcttcaa caccgtggtc
     9181 aggagggggc aggaatcctc tccaatgatc aaggacaact gaagcgccat cgtgacatgg
     9241 ggcttttatc agaagttttc agaaatccag ccaatttgga taaattgaca ggagctggtg
     9301 cgattgggca tgtgcgttat gcgactgctg gcgaagcttc tgttgataac atccaaccct
     9361 tcctcttccg ttttcacgat atgcagtttg gtttggctca taatggaaat ctgaccaatg
     9421 cagcctctct caagaaagaa ctggaacaaa gaggagcaat tttcagcgcg acttcggact
     9481 ctgaaatctt ggctcacctc attcgtcgca gtcataatcc tagcctgatg ggcaaaatca
     9541 aggaagcgct cagtcttgtc aaaggtggtt ttgcctatat cttgctgttt gaggacaagt
     9601 tgattgcggc tcttgaccct aatggctttc gtccgctttc tatcgggaaa atggccaacg
     9661 gagcggtggt tgtttcctct gaaacctgtg cttttgaggt cattggtgcc gagtggattt
     9721 gtgatttgaa gccaggtgag attgtgatca ttgatgacga gggcattcag tatgacagct
     9781 atacagatga tacccagttg gcgatttgtt ctatggagta tatctacttt gcccgccctg
     9841 attctaatat ccacggtgtc aatgtccata cggcacgtaa gagaatggga gcgcaattgg
     9901 cgcgagaatt taagcatgag gcagatattg tagttggtgt gcccaattct tccctaagcg
     9961 cggctatggg atttgcggaa gaatcaggct taccaaatga aatgggtctg atcaaaaacc
    10021 aatacaccca gcgaactttt atccaaccga ctcaagaatt gcgggagcaa ggagtgcgga
    10081 tgaaactgtc tgctgtttcg ggtgttgtca aaggcaaacg tgtggtcatg gtggatgatt
    10141 ccattgtacg tggaacaacc tctcgtcgta tcgttcagct cttgaaagaa gcgggtgcga
    10201 ctgaggttca cgttgccatt ggaagtcctg cactagcgta tccatgtttc tacgggattg
    10261 atatccagac ccgtcaggag ctgattgcag ccaatcatac ggtcgaagaa actcgccaaa
    10321 tcattggtgc ggacagtctg acttatcttt caattgatgg cttgattgag tcgattggta
    10381 tcgaaacaga tgcgccgaac ggtggtctct gtgtcgctta ctttgacggt gactacccaa
    10441 cgcctctcta tgactacgaa gaagactatc gtagaagttt ggaagaaaag accagttttt
    10501 acaagtaggc gacagattct ccattaaaga aaaggaaaaa acaaatgaca aataaaaatg
    10561 catatgccca gtcgggtgtg gatgttgaag cgggttatga agttgttgaa cggattaaaa
    10621 agcacgtggc ccgtacggag cgtgcaggtg tcatgggagc tcttggtggc tttggtggta
    10681 tgtttgacct ttccaagact ggggttaaag aacccgtctt gatttcaggg actgacggtg
    10741 tcggaaccaa gctcatgttg gctatcaagt acgacaagca cgataccatc gggcaggact
    10801 gtgtggccat gtgtgtcaac gacatcattg ctgcaggtgc ggaacccctc tattttctcg
    10861 actacgtagc gacagggaag aatgaaccag ctaagctaga acaagtggtt gctggtgtgg
    10921 cagaaggttg tgtgcaggct ggtgctgccc tcatcggtgg ggaaacggct gaaatgccgg
    10981 gcatgtacgg cgaagacgac tatgacttgg ctggttttgc ggtcggtgtg gctgaaaaat
    11041 ctcaaatcat tgacggttca aaggtggtag agggagatgt tcttctcgga cttgcttcaa
    11101 gtgggattca ctcaaatggt tactctttgg ttcgtcgtgt ctttgcggat tacacaggtg
    11161 aggaagtcct accagaattg gaaggcaaga aacttaagga agttctactt gagccgactc
    11221 gtatctatgt caaggctgtc ttgccgctca tcaaagaaga gttggtcaac ggcattgccc
    11281 acatcacagg tggtggcttt atcgaaaatg tccctcgtat gtttgcagat gacctagctg
    11341 ctgaaattga tgaaagcaaa gttccagtgc ttccaatttt caaagccctt gaaaaatatg
    11401 gtcagattaa acacgaagaa atgtttgaaa tcttcaatat gggtgtggga cttatgttgg
    11461 cggtcagccc tgaaaatgta gagcgtgtaa aagaattgtt ggatgaagca gtctatgaaa
    11521 ttggtcgcat cgtcaagaaa gaaaacgaaa gtgtcattat caaatgaaaa aaatagcggt
    11581 ttttgcctct ggtaatggct caaattttca ggtgattgcc gaagaatttc cagtggagtt
    11641 tgtcttttca gaccatcgtg atgcctatgt gcttgagcgt gcaaagcagc tcggcgttct
    11701 gtcctatgct tttgaactca aggagtttga gagcaaggca gactacgaag cagcccttgt
    11761 cgaactcttg gaagaacacc agattgactt ggtttgccta gcaggctaca tgaaaatcgt
    11821 tggaccaacc ttattgtcgg cttatgaagg tcggattgtc aacattcatc cagcctactt
    11881 gccagaattt ccaggagctc atgggattga ggatgcttgg aatgctggcg tgggtcagtc
    11941 tggtgtgacc attcactggg tggattcggg tgtggataca ggccaggtca tcaaacaggt
    12001 tcgtgtgcca cgactagctg atgataccat tgacagattt gaagctcgca tccatgaagc
    12061 agagtacagg ttgtatccgg aagtagtgaa ggctctattt acagattgac tttttgatga
    12121 ttcatatgat atctttgatt ttaaattgga gtcagtgttt gttgaagacg gcttcaaacg
    12181 gaggtatttg taatgttaga atctaaaaaa acaactcgat atgtatttta tgtctatctg
    12241 atgttattaa cttggggaat cttatttaag tttgaaacaa atcctgaatt tatagcattt
    12301 ttcttagctc caaggtatat caattggatt ccattttcag aaccactaat agtcgatgga
    12361 aaaattgttt ttgctgaaat gttatttaat ctgattttct ttattccatt aggtgtttgt
    12421 ttccctttga taaaaactaa tttatctagt ttaagaatag tcgggacagg tttcttgatt
    12481 agtttattgt ttgagtgctt acagtatatt ttagcaatag gtataacaga tataacgaat
    12541 ttgactttaa atacgctagg tgtctgtgta ggcttactga tttatcaaat ttttataaga
    12601 gtgttcaaat cacagactag aaaatggatc aatatcttag gtatgcttag ccttggtttt
    12661 gcttatcttg ttttactgtt actgcattta attggtgttt aactaatgat taaaaaggag
    12721 aatataatga ctaaacgcgt cttaatcagc gtctcagaca aagcgggcat tgttgaattt
    12781 gcccaagaac tcaaaaaact tggttgggag attatctcaa caggtggaac taaggttgcc
    12841 cttgataatg ctggggtgga taccattgct atcgatgatg tgactggttt cccagaaatg
    12901 atggacggtc gtgtgaagac cctccaccca aatatccacg gagggcttct cgctcgtcgt
    12961 gacttggata gccacttgga agcggctaag gacaacaaga ttgagctcat tgaccttgtg
    13021 gtggtcaacc tttacccatt taaggaaact atccttaaac cagatgtgac ttatgctgat
    13081 gcagttgaaa atatcgatat tggtgggcca tctatgcttc gttcagcagc gaaaaatcat
    13141 gccagtgtta cagttgtggt agatcctgct gactacgctg tggttttgga tgaattggca
    13201 gcaaacggcg aaacctctta tgaaactcgc caacgtttag cagccaaagt atttcgtcac
    13261 acagcggctt atgacgcctt gattgcagaa tacttcacag ctcaagtggg tgaaagcaag
    13321 cctgaaaaac tcactttgac ttatgacctc aagcaaccaa tgcgttacgg tgagaatcct
    13381 caacaagacg cggactttta ccagaaagct ttgcctacag actactccat tgcttcagcc
    13441 aaacagctca acgggaaaga attgtcattt aataatatcc gtgatgcaga tgctgctatc
    13501 cgtatcatcc gtgacttcaa agatagtcca accgttgtgg ctctcaaaca catgaatcca
    13561 tgtggaattg gtcaagctga tgacatcgag actgcttggg actacgctta tgagtctgac
    13621 ccagtgtcta tctttggtgg gattgtcgtc ctcaaccgtg aggtggatgc tgcgacagct
    13681 gagaagatgc acggcgtttt cctcgaaatc atcattgcac caagctatac ggatgaagcg
    13741 ctagccattt tgatcaataa aaagaaaaac ttgcgtatcc ttgccttgcc atttaatgct
    13801 caagaggcta gcgaagtgga agcagaatac acaggtgtag tcggtggact tctcgtgcaa
    13861 aatcaagacg tggtcaagga aagcccagct gactggcaag tggtgactaa acgtcagcca
    13921 actgagacag aagcgactgc tcttgagttc gcttggaagg ctatcaagta cgtcaaatca
    13981 aatggtatta tcgtgaccaa cgaccacatg acacttggtg ttggtccagg tcaaaccaac
    14041 cgtgtggctt ctgttcgcct tgccattgac caagccaaag atcgtctgga cggggcggtc
    14101 cttgcttcag atgccttctt cccatttgcg gataacgtgg aagaaatcgc caaagcagga
    14161 attaaggcca tcatccagcc cggtggctct gtccgtgacc aagaatccat cgaagcagcg
    14221 gataaatacg gcttgactat ggtctttaca ggtgtgagac attttagaca ttaagaagat
    14281 aaaagggaag aaaacagttt ctttcctttt ttggcttaaa atgctaactg aaacaagatt
    14341 aaaacgaact tttttgatat aatgttggta aataattcgc aaaagaggtt gaggaatgaa
    14401 actgcttgtt gtcggttctg gtggtcgtga gcatgcgatt gctaaaaagt tacttgaatc
    14461 aaaagacgtg gaaaaagtct ttgtagctcc tgggaatgat gggatgactc tggatggttt
    14521 ggaattggta aatatctcta tttccgaaca ttctaaattg attgacttcg caaagaccaa
    14581 tgatgttgct tggaccttta tcggtccaga tgatgccctt gctgctggca tcgtggatga
    14641 ttttaaccaa gctggactta aggcctttgg tccgactagg gctgcagcgg agctggagtg
    14701 gtccaaggat ttcgccaagg aaatcatggt caaatacggc gttccgacag caatatatgg
    14761 cacattttca gatttcgagg aagccaaggc ctatatcgaa aagcatggtg cgcctatcgt
    14821 agtcaaggcg gatggcttgg cacttgggaa gggtgtcgtc gttgctgaga cggttgagca
    14881 agcggtcgaa gccgctcatg agatgctttt ggacaataaa tttggtgact caggtgcgcg
    14941 cgtggttatt gaggaattcc ttgaaggaga ggaattttca ctctttgcct ttgtcaatgg
    15001 tgataagttc tacatcatgc caacggctca ggaccacaaa cgtgcctatg atggcgacaa
    15061 agggcctaac acgggtggta tgggtgccta tgcgccagtt ccacacttac cacagagtgt
    15121 agttgataca gcggttgaca ccattgtcaa gccagttcta gaaggggtga ttaaagaagg
    15181 tcgtccttat ctgggagttc tttacgcagg gcttatcctg acagctgatg gaccgaaggt
    15241 catcgagttc aacgctcggt tcggagatcc agaaactcag cttatcttgc ctcgcttaac
    15301 ctctgacttt gctcaaaata tcacagatat cctggatagc aaggagccaa atatcacgtg
    15361 gacggacaag ggtgtgactc tgggtgtggt tgttgcatcc aagggctacc cgctagatta
    15421 ttcaaagggt gttgagttgc cagtcaaaac cgatggcgac atcattacct actatgcagg
    15481 ggctaagttt gcggaaaata gcagagcact gctctcaaac ggcggacgag tttatatgct
    15541 cgttaccaca gcagataccg tcaaagaagc ccaagccagc atctaccaag aactatccca
    15601 acaaaaaata gaaggactct tctaccgaac agatatcgga agcaaggcaa ttaagtaaag
    15661 atataagaat aacgcgccgt agtcgccaaa cacgataatg gtcgtcgtgg tgaaaagacc
    15721 agaacagtga atgttctggt cagggggaaa cttggagacc gtaggctcaa agtttaggaa
    15781 tgaaaccgaa ggtttgcttc cgcctccatc acctaagacc attatcaaaa agaaaaataa
    15841 aaattcacaa aatacgttaa tggtcgtatg gtttgcgagc gttagcgagc taatatagaa
    15901 taatcaccgc cgttgtgaaa gaacgattgg atgacaatcc aatcgttcag ggaaattgga
    15961 agaccttggg tttccaattt aggcatgaga cacctttggt ggctgctgcc gtccctcaca
    16021 agctaaggtg attgttgaaa aagaggaaaa aggagaagaa atgaaaccag taatttccat
    16081 catcatgggc tcaaaatccg actgggcaac catgcaaaaa acagcagaag tcctagaccg
    16141 cttcggtgta gcctacgaaa agaaagttgt ttccgcacac cgtacaccag acctcatgtt
    16201 caaacatgca gaagaagccc gtagtcgtgg catcaagatc atcatcgcag gtgctggtgg
    16261 cgcagcgcat ttgccaggca tggtagctgc caaaacaacc cttccagtca ttggtgtgcc
    16321 agtcaagtct cgtgctctta gtggagtgga ttcactctat tctatcgttc agatgccggg
    16381 tggggtgcct gttgcgacca tggctatcgg tgaagctgga gcgactaacg cagctctctt
    16441 tgccctccgt ctcctctctg tagaagataa gtccattgcg gatgcacttg ccaactttgc
    16501 tgaagaacaa ggaaaaatcg cagaggagtc gtcaaatgag ctcatctaaa acaatcggaa
    16561 ttatcggtgg cggtcaactg ggtcagatga tggccatttc tgctatctac atgggccaca
    16621 aggttatcgc gctggatcct gcggcggatt gcccggcctc tcgcgtggcg gaaatcattg
    16681 tggcacctta taacgatgtg gacgccctcc gtcagttggc agaccgttgc gatgtcctca
    16741 cttatgagtt tgaaaatgtc gacgctgacg gtttggatgc cgttatcaag gatggacaac
    16801 tccctcaagg aacagatctg ctccgcattt cgcaaaatcg tatttttgaa aaggactttt
    16861 tgtcaaacaa ggctcaagtc actgtggcac cctacaaggt cgtgacttct agcctagact
    16921 tggcagatat cgacttgtcg aaaaactatg tcctcaagac tgcgactggt ggctacgatg
    16981 gtcatggaca aaaggttatt cgttcagaag cagacttgga agcagcctat gcgctagcag
    17041 actcagcaga ctgcgtcttg gaagaatttg tcaactttga ccttgagatt tctgtcatcg
    17101 tgtcaggaaa tggcaaggag gtgacgtttt tcccagttca ggaaaatatc caccgcaaca
    17161 atatcctgtc taagaccatc gtaccagccc gcatttctga aagtctagca gacaaggcta
    17221 aagctatggc agtgcgaatc gcagaacaac tcaacttgtc tggaactctc tgtgtggaaa
    17281 tgtttgcgac tgatgatgac gttattgtca atgaaatcgc cccacgacca cataactctg
    17341 ggcactattc tattgaaacc tgtgatttct ctcagtttga cacccatatt ctgggtgttc
    17401 tcggagcacc attaccagtc atcaaactcc atgcgccagc cgttatgctt aatgtcctcg
    17461 gtcagcatgt cgaggctgct gagcaatatg tgacagaaaa ttcaagcgcc cacctccaca
    17521 tgtatggtaa aatagaagca aagcataatc gtaagatggg acatgtgact ttgtttagtg
    17581 atgtgccgga tagtgtggaa gagtttgggg aagggattga tttttaggac aagtctatga
    17641 tacaaattat cgttaataca tttattgaaa aggataagac tggagcagtt gttgaagtgt
    17701 tgtatgccag tgctgaccaa gataaggtac aagctaaata tgaagaacta gctgcacaat
    17761 accccgaaaa ttatttagct atctatgatg taccgctgga tacggatttg aatacactag
    17821 atcattaccc gtctgtgttt attgaaaaag aggagtttga gtagaaatct tggtttacct
    17881 agatagctta ttcccaacag cttaagaaga aaggaaaaat taacacatga tcaaccgtta
    17941 ctctcgccct gagatggcga atatttggag tgaagaaaat aaataccgtg cttggcttga
    18001 ggtggaaatc ctctctgacg aggcatgggc tgagttgggg gaaatcccta aggaagatgt
    18061 ggctttgatt cgcaagaagg cggactttga catcgaccgt attttggaaa ttgagcagga
    18121 gacgcgccac gatgtggtgg ctttcacgcg tgcggtttct gagactcttg gtgaagagcg
    18181 caagtgggtt cactatgggt taacttctac cgacgtggtg gatactgctt atggttacct
    18241 ctacaagcag gccaacgaca tcatccgtcg tgaccttgaa aacttcacta atatcatcgc
    18301 tgacaaggcc aaggagcaca agttcaccat catgatgggg cgtactcatg gtgtgcacgc
    18361 tgagccgaca acctttggtc ttaaattggc aacttggtac agcgaaatga aacgcaatat
    18421 cgagcgtttc gagcatgcag ctgctggtgt agaagctggt aagatttctg gtgcggttgg
    18481 gaactttgcc aatatcccac catttgtaga ggagtatgtc tgcgataaac ttggcatccg
    18541 tgcccaagaa atctctacac aagtccttcc tcgtgacctt cacgctgagt actttgcggt
    18601 tcttgccagc attgcgactt caatcgaacg tatggcgact gagattcgtg gtctacaaaa
    18661 atctgagcaa cgcgaagtag aagagttctt tgctaaaggg caaaaagggt cttcagcaat
    18721 gcctcacaaa cgcaacccaa tcggttctga aaatatgact ggtctggcgc gtgtcattcg
    18781 tggtcacatg attacggctt atgaaaacgt cgctctctgg cacgaacgcg atatttctca
    18841 ctcatcagct gagcgtatca tcacaccaga tacgaccatt ttgattgact acatgctcaa
    18901 ccgttttgga aatatcgtca agaacttgac agtcttccca gaaaatatga tccgaaacat
    18961 gaactcgact tttggtctta tctttagcca acgggctatg ttgacattga ttgaaaaagg
    19021 catgacccgt gagcaagcct atgacttggt gcaaccaaaa acagcctact cttgggacaa
    19081 ccaagtagac tttaaaccac ttcttgaggc agattcagaa gtaacatcac gtctcactca
    19141 agaagaaatc gatgaaatct tcaacccagt ttattacacc aaacgagtgg atgatatctt
    19201 tgaacgtctt ggactaggtg attaattaaa aaataaacag cgagcttcaa tctcgctgtt
    19261 tattttttat cgaaaagact tagtcttctt ttcttttagt gagtccatag gctgctagtg
    19321 tggacatgag tcctgcgact actagtcctg cagaatcgtg agttcctgtt tcaggaagtt
    19381 ttttctctgt taccacagga gctggatctt gaggaagagc tttgctttcc tcagcaggag
    19441 cagttgatgg agctggttgg cttgggattt ctagttttgg tttttcttca gcaatagcgg
    19501 cttgtccgtt ttcatcgcct acatgtgtta ccatagttcc gacttcgact atttgagtaa
    19561 cggcttcctg tgctacgaca ctatttacaa gtgttttcac ttccttacca tcggcagaag
    19621 tgctcacaga gtagaagttg ctacgatgtc cattgacgcc cttagtaatg acttgtgttt
    19681 ttcctttgag taagagtgga ttttcacgag tcactgtggt aaatggaatt tcttcttttt
    19741 ggatatccag tctaggtttt acctcagtag ttggtgcaag accactttca tcacccttgt
    19801 gagttacagg agcgccaact tcaaccactt ggtttataac ttctttggtt acctggctat
    19861 caaggactgt ttctgttgtt tttccatttt cagtgagtac agagatgtaa tgagttcgtt
    19921 cacctttgac tcctgctgtg ataatatttt cttgaccagc tgggaggtta ggattttctt
    19981 tcttgataac ttcaaatgga atttcttcag ttcttgtgat gagttctggt ctggtttcaa
    20041 cattggcagc cacttcattt tcatctaggc ttcctgaatg agttgcagct ggtttgaggc
    20101 cttgaagagc ggcttttagg ttggctacaa gtgtgtcaag ctcagcttgt ttattacggt
    20161 tgaggttgta atttagagct gttttagctg cgtcaagggc ctcaagactt tctttactat
    20221 atccttctaa gtttgtagga attttagcta attcttcgcg gagagcatta taattagcac
    20281 ggaagtagtc tttgttgtgg tctgcaaagg cagtcatgag ttcaaagatt tcctcttcct
    20341 tgtattcagc gcttggtcta tctgcccaga ttgaaagcat acttccgact gttggaagat
    20401 ctacttcagg atatttggta gaagctagtt gattgaatgg aactttacca gaattttcaa
    20461 ctgcttttga aagagggtaa gcttcctctt gtttgtgatt gcctataaca taataccagt
    20521 caccgttggt attcaagaat ttatagcctt tgcttgctag gtattgaggt gatgcgaggt
    20581 tatatcccca ccagccttta gaccagtaag aaatcaagac atctttgtca aactgaacat
    20641 cgtccttgtc ttcatagtag aagccatcgt tgaaggccat tggttgaagc cctctttctt
    20701 tggccatagc tgcgagggtg ttggcatatt cggcaaattt gccatagagt tgataccact
    20761 tgaggtagta ccagccttgg gcactagtcg catcgttggc gtattcgtca gtaccaaagt
    20821 tgaaaatctt tgttttacct gcaaagaagt ccatgtattt accgatgagg gcttttacaa
    20881 agtccatcgc ttcttcgttt ttcaagtcca tagttgtttt tgaaacttta tcaaagtggg
    20941 cttgaggatt tttaatacct aatttttcca tggcaaccag catagcatcc atgtgacctg
    21001 gactgttaat agctgggatg agaccgatgt ccttagattt agcgtattca attagctctg
    21061 tcacttctgc ctgtgttagt gcagtaccgt ttggatcgtc gtagtaagct ttagttcctt
    21121 cgataatagc ttttttaacg tcatcactag cataggtttt tccgttggca gtaatggtca
    21181 tatcattgag tagaaagcga agtccgtcat ttcctagaag gagatggaca tcagaatatc
    21241 cgagctcact ggccttgtct acgatgcgtt tgagctggtt cagagtaaag tatttgcgtc
    21301 cagcatcgat tgagattacc ttgtttttgg caagtttttc aacctcacgt ttagcttctt
    21361 cttctttttg agcttcaggc gtgagggtca agttgttgac agtttcttga agtttagcaa
    21421 tggcttgatc aatcgtatct tgttgggcac ggctaaggtt gctatcgaga gagcgaatag
    21481 ctttttcagc ttcttttacg gccgcgacgc tttctgcagt ataacggttc aggtcttttg
    21541 gtacctcgtt aagtgcttgc tctgcagatt cataatcagc tgcgaagtat tcagcgttgg
    21601 catttgcaaa atgacgcatg agtttgaaga ggcgtgatgg tgaataacgt gcagatggag
    21661 tgtcagccca agcagctacc ataccaccga tgattgggat atcagctcct tctgtttttg
    21721 gtacagaagt gattggtgtg tttttaatac cattgagccc ctgatcgaga ttgtaccagc
    21781 cttggccatc agcgtttcgt ccaagaacgt agtaccaagc atcattggta ttaaggattt
    21841 ggtgaccttt ttcagctagt agtttagaag aagcgacatc gtagcctccc caaccaccag
    21901 tccacataga aacgatgatg tctttgtcaa aactaccaaa gcttgtgtcg ctattgtagt
    21961 agataccgtc gttaaaggcc attggtttga gaccgtgcga ttttacaata cgagcgaggt
    22021 cattggcgta ggcaataaat ttttcatagc cttttacagg gtagccttcg tttggatagt
    22081 atttatcagc ttgaagcaca ctccaacctt tagcatctgt cgcatcattg gcatattcat
    22141 caagtccgat gttgaagatt tcagtctttt tcgcgaaata agcagcatac ttgtcgataa
    22201 gggcttttgt aaaagcgaca gcttgttcgt tgtcaagatc gacagtacgg gctgatttct
    22261 tcccaaaata gctaaagtta gggttttgga ttcccaattc tttcatggca ttgagaatcg
    22321 catccatgtg tccaggacta tttactgtcg gaatgagacc gataccttta tctttggcat
    22381 agttaatcag atctgtcatt tgactttctg ttaagtgatt gccgtttgga tcgttgtaat
    22441 aatcatttgt acctttttca atggcgcgtt tgacatcgtc actggcatag gtcttgccgt
    22501 tagctgtgat gctcatatcg tccaacatga aacggagtcc atcatttccg actaataggt
    22561 gtaaatcagt gtagccataa tgtttcgctt tatcgatgat ttccttgagc tgttctggtg
    22621 agaaatattt acgtccagca tcaatagaaa caattttctt tttcgctagt ttttcattta
    22681 cagttgcagc acgttccttt cctgcctctg tttccggttt gtcagcctct gctttcgctt
    22741 catctttttt agctggttta tccttgtcag tcttgtctgt atttgactct ttagaatcaa
    22801 cctctttcgc ttcttccttt ttagggctag cttcttctgc ctttttatta gcagtttctt
    22861 tttcagcaga agttggagtt accacctctg ctttatcact aggagttgaa ctaacttcct
    22921 cttgtggttt ttcttctgtt tttggaagac tagctacctt atcagtagct ggagtttctg
    22981 tttctacagt ttttggagct tctggttgaa gctctgcttt aggtgtttcc tcagtccgat
    23041 tttcggatga ttgaggggaa tcagaaactg tatggatggt cggttggttt tctgtagtag
    23101 tagtagtaac tccatcggct gcaacagtct gtgcttggaa ggcaaatcca attagaacag
    23161 aagctgctcc tacagcgtat ttacgaatag aaaaacgctg ttgtttttca tgtttcattg
    23221 caaaacctcc tgattgcatt gttatattga tagcgattat ataaatcaac gcccttattt
    23281 tatttcttat attaacgaga gtcaagagga gatgacaaaa aactataata agtataaaaa
    23341 aatataaaat ttaaacttaa gatttcagat tggtcggaaa aaatgcatat atatatctaa
    23401 tataattttt ggttctattt ctataaaata ttccacaaat tatagaatct tccaaaaata
    23461 ggtaagcgct acctttttgg tgtggtataa taagcataga aaaagcccga gcgattaggc
    23521 tcaggctttc ttcttagtga tcacggtcac atgagataaa tttaatcttg tagtaatcag
    23581 atcgtttgta agtttcactg tattctaaaa cttggccagt tgattcgagt ttggtgattt
    23641 tagtttgtag gacagtaggg aattgttcat cgactccgag gactgaagcc gcatgttctg
    23701 gagttggaaa gactatttcg ttgatttctt caaagtgttc atcattcatg tgaatgtggt
    23761 agtctaactt gaaacgatta tagatagaac tatagtattc aaggtttgga taatttgcgt
    23821 tgatatattg ttctgggatg taggatgtat ggtagatata aacgacaccg tttgattcgc
    23881 ggatacgttc aatcttgtag tagaattgat cgccgcgtag acccaatttt tccaagtaaa
    23941 caagcttgtt tccgcgttca attgaaagaa cagttacctt atcatcttta gcattgaaga
    24001 gttcaatatc tgaaaactct acaagcttgt gtttgcgtgc acgtgaaacg aaggttcctt
    24061 ttccttgttg gcggacaata tagccatctt tggcaaggtc gtttaaggcg cgaacaactg
    24121 tgatagagct gacatcgtac attgaaatga gttctgcttc agtgtaaaat ttatctccac
    24181 tgctaaactg cccagagatg attttatttt ttaattcgtc ttttatgtat tgatatttgg
    24241 gaattgccat atttttacct ctattttcct tctccataga aaattttacc ataaaagcga
    24301 aaaaaatagt agtcttttga ataaaaaatt agaataatag tttgaaaaat taagcgatat
    24361 agggattgct catattttat caatgtattc tatacaaaat tattttaggt cctatattcc
    24421 gaatttaaag agcgtttgaa atgggtctaa aaatgtttga aactaattga atgtgtgtat
    24481 aatagtaaaa atgcagtaaa tatcccgaca atttctattg acaattcaaa cagattggtt
    24541 tataattaat ataacaacaa atgaaagcgc aaactttcgc ggtcggaagg tagttttatg
    24601 acacgatttg agatacgaga tgatttctat ctcgatggaa aatcatttaa gattttatct
    24661 ggtgccattc attattttag ggttcctcca gaggattggt atcattcgct ctataacttg
    24721 aaggctcttg gttttaatac ggtagagact tatgttgctt ggaatttaca cgagcctcgt
    24781 gaaggtgagt ttcattttga aggtgatctg gatttagaga aatttctcca aatagcgcag
    24841 gatttgggtc tctacgcaat tgtgcgtccg tctccattta tctgtgcgga atgggaattc
    24901 ggtggcttac cagcttggct cttgaccaag aacatgcgaa ttcgctcatc cgacccagca
    24961 tatatcgagg cagttggtcg ctactatgat cagttattgc caagactggt gcctcgtttg
    25021 ttggacaatg gtggcaatat tctcatgatg caggttgaaa atgagtatgg ttcttacgga
    25081 gaagataagg cttacctgag agcgattcga cagctaatgg aagagtgtgg cgtaacctgt
    25141 cccctcttta catcagatgg tccatggcga gctactctga aagctggaac cttaattgaa
    25201 gaggacctct ttgtaacagg aaactttggt tctaaggcac cttacaactt ttcgcagatg
    25261 caggaattct ttgatgaaca tggtaagaaa tggccactca tgtgtatgga gttctgggat
    25321 ggttggttca atcgctggaa agaaccgatt atcacacggg atcctaagga attggcagat
    25381 gcagttcgag aggttttgga acaaggctct atcaatcttt acatgttcca cggtggtaca
    25441 aactttggtt tcatgaatgg ttgctcggct cgaggaactt tggacctgcc acaagttacg
    25501 tcttatgatt acgatgccct tctggatgaa gaaggaaatc caactgctaa atatcttgca
    25561 gtcaagaaga tgatggcaac acatttttca gagtatccgc agttggaacc actctacaaa
    25621 gagagtatgg agttggatgc tattccacta gttgaaaaag tttctttatt taaaacctta
    25681 gatagcttgt caagtcctgt agaaagtctc tatcctcaaa agatggagga gctgggacaa
    25741 agttatggct acctacttta tcgaacagaa acaaactggg atgcagaaga agaaagactt
    25801 cgtatcattg atggtcgaga tagggcccag ctgtatgtcg atggtcagtg ggttaaaact
    25861 caatatcaga cagagattgg ggaagatatt ttttatcaag gtaaaaagaa agggctatct
    25921 aggttagata tcttgataga aaatatgggg cgtgtcaact atgggcataa gttcttagcg
    25981 gatacgcaac gtaagggaat tcggacaggg gtctgtaagg atctgcattt cttactaaac
    26041 tggaaacact atccactccc actagacaat cctgagaaaa ttgatttttc aaaaggatgg
    26101 actcaaggac aaccagcctt ttacgcttat gactttacag tcgaagagcc aaaagatact
    26161 tacctagact tgtctgagtt tggtaagggg gttgcctttg tcaatgggca gaatctagga
    26221 cgtttttgga acgttggccc aactctctca ctttatatcc ctcatagcta tctcaaggaa
    26281 ggtgccaacc gcatcattat ctttgaaaca gaaggtcaat ataaagaaga gattcattta
    26341 actcgtaaac ctacactaaa acatataaag ggggaaaact tatgacaatt gtaggatgcc
    26401 gtattgatgg acgtttgatc cacggacaag tagccaatct ttgggctgga aaactaaatg
    26461 tttcacgcat tatggttgta gacgacgaag ttgtcaacaa cgatattgaa aagagtggtt
    26521 tgaaacttgc gacaccacca ggtgtgaaat tgagtatttt gccagttgag aaagctgcag
    26581 ccaatattct tgctggcaaa tacgatagcc aacgtctctt tatcgtggct cgtaaaccag
    26641 accgcttcct tggtttggta gaagcaggtg taccacttga aacccttaat gttgggaata
    26701 tgtctcaaac accagaaact cgttctatta cacgttctat caacgtagta gacaaggatg
    26761 tggaagactt ccacaaactg gcagaaaaag gtgttaaact tactgctcag atggttccaa
    26821 atgatccaat ttcagacttt ttgagcttat taaaatagga aaaaaatttt taggaggtca
    26881 ttgttatgat acaatggtgg caaattttac ttctcacttt gtactcagct tatcaaatct
    26941 gtgatgagtt gacgatcgtt tcatctgcag gttcccctgt atttgctggt ttcattactg
    27001 gtttaatcat gggagatgtg actactggtt tacttatcgg tggtaacttg caactgttcg
    27061 ttcttggggt tggtactttc ggtggtgctt ctcgtatcga cgcaacttct ggtgcggttc
    27121 ttgcgacagc cttctctgtt tcacaaggaa ttgatgcacc gcttgccatt actacaatcg
    27181 ctgtaccagt agcagctctc ttgacttact tcgacgttct tggtcgtatg actactacct
    27241 tcttcgctca ccgtgtggat gctgcaatcg aacgctttga ctataaaggt attgaacgca
    27301 actacttgct tggtgcgatt ccgtgggctc tatctcgtgc ccttccagtc ttctttgccc
    27361 ttgcttttgg tggtgccttt gtacaatcag tagtagactt cgttgaagcc tacaaatggg
    27421 ttgcagatgg cttgacactt gcaggacgta tgcttccagg tcttggattt gcaatcttgc
    27481 ttcgttacct tccagttaaa cgtaaccttc actaccttgc tatgggattt ggtttgacag
    27541 ctatgttgac tgttctttac tcatatgtaa caggtcttgg tggcgctgtt gctggtatcg
    27601 taggtactct tcctgctgaa gttgctgaaa aaattggttt cgtgaacaac ttcaaaggtt
    27661 tgtctatgat tggtatttct atcgtaggta ttttccttgc agtgcttcac ttcaaaaata
    27721 gccaaaaagt agctgtagca gcaccttcta caccatcaga aagtggggaa atcgaagatg
    27781 acgaattcta attacaaact tacaaaagaa gattttaatc aaatcaacaa acgtagcttg
    27841 tttactttcc aattaggttg gaactacgaa cgtatgcaag cttctggtta cctttacatg
    27901 atcttgcctc agttgcgtaa aatgtatggt gatggaactc ctgaattgaa agaaatgatg
    27961 aaagttcata ctcaattctt caatacttca ccattcttcc ataccattat cgctggtttt
    28021 gaccttgcca tggaagaaaa agatggtgta ggttcaaaag acgccgttaa cggtatcaag
    28081 acaggtttga tgggaccatt cgctcctctt ggggatacaa tctttggttc acttgtacct
    28141 gctatcatgg ggtcagtcgc agcaactatg gctatcgctg gccaaccttg ggggatcttc
    28201 ctttggattg cagttgcagt agcgtatgac atcttccgtt ggaaacagtt ggaatttgct
    28261 tacaaagaag gggttaacct tatcaacaac atgcaaagta ccttgacagc tttgattgac
    28321 gctgcatctg tacttggtgt cttcatgatg ggtgctcttg tagcaacagt gattaacttt
    28381 gaaatttctt acaagttgcc aatcggtgaa aagatgattg atttccaaga catcttgaac
    28441 caaatcttcc cacgtttgct tccagcaatc tttactgcct ttatcttctg gttgcttggt
    28501 aaaaaaggta tgaactctac taaagctatc ggtattatta tcgtacttgc tttggctctt
    28561 tctgcccttg gtcactttgc acttggaatg taattcctta tgactaaatc attaattttg
    28621 gtgagccatg gtcgcttctg tgaggagctt agaggtagca cagaaatgat tatgggccca
    28681 caagacaaca tttacacagt agctcttctt ccagaagatg gcccagaaga atttactgct
    28741 aaatttgaag ctgttattga agggttggat gatttcctag tctttgcgga tcttctcggt
    28801 gggacacctt gtaatgtggt gagtcgcttg atcatggaag gtcgtgatat tgacctttac
    28861 gcagggatga atcttccaat ggtgattgaa tttatcaatg cgagccttac aggcgcagat
    28921 gcggactaca agagccgtgc tgcagaaagc attgtgaaag ttaatgacct gttagcgggc
    28981 ttcgatgatg acgaagatga ataatactct tcgaaaatct cttcaaacta cgtcaacgtc
    29041 gccttgccgt aggtatatgt tactgacttc gtcagtctta tccggcaacc tcaaaacggt
    29101 gttttgagct gacttcgtca gttctatctg caacctcaaa gcagtgcttt gagcagcctg
    29161 cggctagttt cctattttag ttggaactcg attcaattca tgtgacaacg tgaaaatcgt
    29221 tagagcattt tatatagaat atacatggga atgtagctta ctcccattcc catatttaat
    29281 agaaaaagag gaactcaatg ctacattata caaaagaaga cttgctcgaa ttgggtgcag
    29341 aaatcactac gcgtgaaatc taccaacagc ctgatgtatg gagagaagct tttgaatttt
    29401 atcaagcaaa acgtgaagaa attgcagcct ttctacaaga aatcgctgat aaacatgact
    29461 atattaaggt tatcttgaca ggtgctggga cttctgctta tgtgggagat accttgctac
    29521 cttactttaa ggaagtctat gacgaacgca aatggaattt caatgctatt gcgacaacag
    29581 atatcgttgc caaaccagca acctatttga aaaaagatgt ggcaactgtc cttgtgtctt
    29641 ttgctcgtag tgggaactcg cctgaaagtg tggcgactgt tgatttggcc aaatccttgg
    29701 tggatgagct ttatcaagtg atgattactt gtgcagcaga tggtaaattg gctcttcaag
    29761 ctcacggtga tgaccgtaat ctcttgctct tgcaaccagc tgtctctaat gatgctggat
    29821 ttgccatgac ttctagcttt acgtctatga tgttgacagc tctcttggtc tttgatccta
    29881 cagaatttgc tgttaagtct gaacgttttg aagttgtatc tagtcttgcc cgtaaagttt
    29941 tagacaaggc agaagatgtc aaagagctcg ttgatttaga ctttaaccgt gtcatctatc
    30001 taggcgctgg tcctttcttt ggacttgctc atgaagctca gctcaagatt ttggaattaa
    30061 ctgctggtca agttgcgacc atgtatgaaa gcccagttgg cttccgtcac ggtccaaaat
    30121 ctcttatcaa cgacaataca gttgttttgg tctttggtac aacgacagac tacactcgta
    30181 agtacgactt ggacttggtt cgtgaagttg ctggtgacca gattgctcgt cgtgttgtgc
    30241 ttttgagtga tcaagctttt ggtcttgaaa atgtcaaaga agtggccctt ggttgtggcg
    30301 gtgtcttgaa tgatatttac cgtgtcttcc cttacatcgt ttatgcccaa ctctttgccc
    30361 tattgacttc actcaaggta gaaaataaac cagatacacc gtctcctaca ggtacagtaa
    30421 accgtgtagt acaaggtgtc ataattcacg aatatcaaaa gtaagacagt gtttatgaat
    30481 tcttgacaag aggatttgta aattatcaga taaaccatag attgtcagta cgctttctat
    30541 ggtttgtttg cttgagagaa atagtaaaag gagaacagaa tgaaagcata cacagagcgt
    30601 gtatttggaa atgttgaggg cgaggatgtc ttggcctatc gatttgagac agacggtggc
    30661 taccaacttg aggttatgac ttatggtgcg accatcttgc gctatgtcgc acctgacaag
    30721 gctggaaatt ttgccaatgt tatcttggga tttgatgact ttgatagtta tgtaggcaat
    30781 agtcccaagc atggagcaag tgtaggtcct gtagcgggtc gtattgcagg tgcgaccttt
    30841 gagctcaatg gtaagaccta tgaccttgag gttaataatg ctagcaactg taatcacagt
    30901 ggttcaactg gttgggattc cagcttgttt gaagttgaag aagtaagcga tcatggcttg
    30961 actctctaca cagagcgtac agatgggaca ggagggttcc ctggaaatct caagatttgg
    31021 atcagttatc acttggaaga aactggtgcc tatgaaatca gctacaaggt aacgaccgat
    31081 caggatacgc tggtcaatcc aaccaaccac agctatttca acttgtctgg tgatttcacg
    31141 cagacgattg accgtcatgt cttccaacta aacacagagg gcatttactc aatcgctcct
    31201 gacggtgttc ctgccaaaac tccagaagcc aaccgtgatg tggtcaaaca catctacaat
    31261 ggtaccttgt tgaaggatat ctttgcagaa gaagatgagc aaatccagct ggcatcaggt
    31321 ttggatcacc catttgccct tcctgtaggc catgacaatg ctggattcct ttatgaccaa
    31381 aattcaggtc gcttcctgct tttcaagaca gaagctcctt gctttgtggt ctacacagca
    31441 aactttgtgg atgaaagtgt catcatagga ggtcagccaa tgctacagca caatgggatt
    31501 gctcttgaag cgcaagcttt accagatgcc attcacagtg accttaaagg ccaagtcatt
    31561 cttaaagctg gtcaaacctt caccagtaag acacgttatg aacttgttgt gaaataaaaa
    31621 agctggtcaa aaagtcttta aaattaaaat aacgcatatt gtcaggtgat gaaaagtttg
    31681 ataatatgcg ttttattatg aaatgattta ctttatatta tcctgaaatg gtgttatttt
    31741 tgagttatct ggcttgactt tcttgatgga aattatataa taattataat tacaacgaga
    31801 aaagaggacc atttatgacc tatgaatata agagtcacat ttatttggca gagacagttt
    31861 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    31921 tcttatctca aactgagaca gagtccattc taggccttgg tgaaaaagtc ttggtacagc
    31981 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    32041 ttctcttgcc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    32101 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    32161 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    32221 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    32281 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttccg
    32341 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    32401 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    32461 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    32521 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    32581 ttgacgcacc aatcaaatgg atgacatcga gcaaattgga aatcacagac tcagatggca
    32641 tcgtgacccg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    32701 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    32761 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    32821 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    32881 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    32941 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    33001 ctgaagctca aaaggaacgc ttagaaaagg ctatccgata cttgattaaa cggaaataaa
    33061 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttggaatagt ttaatgggag
    33121 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtattgaaa
    33181 tgtactgacc ccaaaaagtt agattttttc tgtctaactt ttggggtgca gttcataaga
    33241 accttggtaa tatgcgtttt attatgggga gatttatact tttcgaaaat ctcttcaaac
    33301 caggtcagct tcaccttgcc gtagatatgg ttactgactt cgtcagttct atccacaacc
    33361 tcaaaacagt gttttgagct gacttcgtca gttccatcca caaccttaaa acagtgtttt
    33421 gagcagcctg cggctaactt cctagtttgc actttaattt tcattgagta ttacttcatc
    33481 ttctcatgaa attgagtttt tgcccagctc ctcttgatta ttctacttga ccaggccaag
    33541 cattcatacc accttctacg ttggtaacgg tgaggccttg ggagatgaga aattggcagg
    33601 tagatgcaga gcggactcct ccttgacaaa taacatagta ttcatggtca ggtttgagtt
    33661 ctttgtagcc ttgctctaag gtacttaatg gaagattttt ggcacctggt gcatgtcctg
    33721 cttggaattc atgtgcttca cggacatcga taagttctag attttcattt tggtattttc
    33781 cataaaagtc agccatgctg atactagttt ccatattcta ctccttctgg gttaaccatt
    33841 ttgtatagtg aataagcgcc gtcaaggttt tgggcggtaa atcctgcttg cttgaggata
    33901 ggctctgcga tatagctgcg caaaccactg tggcagctga cgatgtaggc ttgttttttg
    33961 tccagttcat cagcttcctc cttgacactc ggtcagattt tgatacaata gtacaaaatt
    34021 agaggaggca ggctatgatt cagaaacatg cgattcctat tttagagttt gatgacaatc
    34081 ctcaggcggt tatcatgccc aatcacgagg ggctggactt gcagttgcca aagaagtgtg
    34141 tttatgcatt tttaggtgag gagattgacc gctatgcgag ggaagtaggg gcgaactgtg
    34201 ttggcgaatt tgtttctgcc accaagacct atccagtcta tgtcatcaac tacaagggtg
    34261 aggaggtctg tctggctcag gctcctgttg gctccgctcc agcagcccag tttatggatt
    34321 ggttggttgg ctatggtgtg gagcagatta tctctactgg gacctgtggt gtcctagctg
    34381 atatagagga aaatgccttt ctagtccctg ttcgcgctct gcgagatgaa ggagccagtt
    34441 accactatgt ggcaccttct cgttatatgg aaatgcagcc agaggctatt gctgctattg
    34501 aggaagtttt ggaagacaga gggattcctt atgaagaagt catgacctgg acgacagacg
    34561 gtttttaccg agaaacggct gaaaaggtgg cttatcgtaa ggaagaaggc tgtgctgttg
    34621 tggagatgga gtgttccgct cttgcggcag tagctcaatt gcgtggggtt ctctggggtg
    34681 aattgttgtt cacagcagat tctctagcgg acttggacca gtacgacagt cgtgactggg
    34741 gctcggaagc ttttaataag gcgctagaac tgagtttagc aagtgttcac cacctttagt
    34801 tgtactggca aaggatttgt tttatcataa aatgtctagc tcatactttt caaaaatatg
    34861 tttaaacgag gtcaccttcc tcttgtccta ggcatgttga ggttgggaaa aatctttaaa
    34921 atcagaaaaa cgtatcatat caggtgatga aaactttgat actatgcgtt ttatgttggt
    34981 aagatttaga gtgagatgaa atgatactct tcgaaaatct cttcaaacca ggtcagcttc
    35041 accttgccgt atagatgtta ctgacttcgt cagttctatc tgcaacctca aaacagtgtt
    35101 ttgagctgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag caacctgtga
    35161 ctagctttct aagcgatgcc ttggttctca ttgcctataa tcaaaaagag aaattttctc
    35221 ctgaaaagca tatagagtag ctggcgttaa aagctcctgt cttgcttttt tgacctatag
    35281 tcacatctat caagtattgt tcttgcctaa gctatcaata aaaaggtggc attttttagg
    35341 cttggtgtta gtagattttg ccttatccta tctaagtcat ttcgaacttt ttatggtaca
    35401 atggaaacat gttattcaaa ttatctaagg aaaaaataga gctaggctta tctcgtttat
    35461 cgccagcccg tcgtattttt ttgagttttg ccttggtcat tttactaggc tctcttcttt
    35521 tgagcttgcc ctttgtccaa gttgaaagct cacgagcgac ttattttgat catcttttca
    35581 ctgctgtctc tgcagtctgt gtgacaggtc tctcaaccct tccagtagct cacacctata
    35641 atatatgggg ccaaataatc tgtttgctct tgattcagat cggtggtcta gggctcatga
    35701 cctttattgg ggttttctat atccagagca agcaaaagct tagtcttcgt agccgtgcaa
    35761 ctattcagga tagttttagt tatggagaaa ctcgatcttt gagaaagttt gtctattcta
    35821 tttttctcac gacctttttg gttgagagct tgggagctat tttgcttagt tttcgcctta
    35881 ttcctcaact tggctgggga cgtggtcttt ttagttccat ttttctagcg atctcagcct
    35941 tctgtaatgc cggttttgat aatttaggga gcaccagttt atttgctttt cagaccgatt
    36001 tactggtcaa tctggtgatt gcaggcttga ttattacagg cggccttggt tttatggtct
    36061 ggtttgattt ggctggtcat gtaggaagaa agaaaaaagg acgtctgcac tttcatacta
    36121 agcttgtact attgttgact ataggtttgt tgttatttgg aacggcaact actctctttc
    36181 ttgagtggaa caatgctgga acgattggca atctccctgt tgccgataag gttttagtta
    36241 gcttttttca aacagtgacg atgcgaacag ctggcttttc tacgatagat tatactcagg
    36301 ctcatcctgt gactcttttg atttatatct tacagatgtt tctaggtggg gcacctggag
    36361 gaacagctgg gggactcaag attacgacat tttttgtcct cttggtcttt gcacgaagtg
    36421 agcttctagg cttgcctcat gccaatgttg cgagacgaac gattgcgccg cgaacggttc
    36481 aaaaatcctt tagtgtcttt attatctttt tgatgagctt cttgatagga ttgattctgc
    36541 tagggataac agccaaaggc aatcctccct ttatccacct catatttgaa accatttcag
    36601 ctcttagtac agttggtgta acggcaaatc tgactcctga ccttgggaaa ttggctctca
    36661 gtgttatcat gccacttatg tttatgggac gaattggtcc cttgaccttg tttgttagct
    36721 tggcagatta ccatccagaa aagaaagata tgattcacta tatgaaagca gatattagta
    36781 ttggttaaga aaggaaagat catgtcagat cgtacgattg gaattttggg cttgggaatt
    36841 tttgggagca gtgtcctagc tgccctagcc aagcaggata tgaatattat cgctattgat
    36901 gaccacgcag agcgcatcaa tcagtttgag ccagttttgg cgcgtggagt gattggtgac
    36961 atcacagatg aagaattatt gagatcagca gggattgata cctgcgatac cgttgtagtc
    37021 gcgacaggtg aaaatctgga gtcgagtgtg cttgcggtta tgcactgtaa gagtttgggg
    37081 gtaccgactg ttattgctaa ggtcaaaagt cagaccgcta agaaagtgct agaaaagatt
    37141 ggagctgact cggttatctc gccagagtat gaaatggggc agtctctagc acagaccatt
    37201 cttttccata atagtgttga tgtctttcag ttggataaaa atgtgtctat cgtggagatg
    37261 aaaattcctc agtcttgggc aggtcaaagt ctgagtaaat tagacctccg tggcaaatac
    37321 aatctgaata ttttgggttt ccgagagcag gaaaattccc cattggatgt tgaatttgga
    37381 ccagatgacc tcttgaaagc agatacctat attttggcag tcatcaacaa ccagtatttg
    37441 gataccctag tagcattgaa ttcgtaaaga gggatgaccc ctcttttttg atgcccaaga
    37501 tggcaaatag agacagaagc cccttgtctt ctagttaaaa gttcttcaaa ggctggactt
    37561 tatgataaaa tagaaagaag tgacaagaga gagtaatact caatgaaaat caaagatcaa
    37621 actaggaaac tagctgcggg ctgctcaaaa cactgttttg aggttgtgga tagaactgac
    37681 gaagtcagct caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaacatc
    37741 tatacggcaa ggcgacgttg acgcggtttg aagagatttt cgaagagtat aagaaaaaat
    37801 cagtccccta aaggagcaga ttatgaagtt attgtctatc gccatttcta gctataatgc
    37861 agcagcctat cttcattact gtgtggagtc gctagtgatt ggtggtgagc aagttgagat
    37921 tttgattatc aatgacgggt ctcaggatca gactcaggaa atcgctgagt gtttagctag
    37981 caagtatcct aacatcgtta gagccatcta tcaggaaaat aaaggccatg gcggtgtggt
    38041 caattgcggt ttggcagagg cttctgggcg ctattttaaa gtagttgaca gtgatgactg
    38101 ggtggatcct cgtgcctact tgaaaattct tgaaaccttg caggaacttg agagcaaggg
    38161 tcaagaggtg gatgcctttg tgaccaattt tgtctatgaa aaggaaggtc agtctcgtaa
    38221 gaagagtatg agttacgagt cagtcttgcc tgttcggcag atttttgact aggaccaggt
    38281 cggaaatttc tccaaaggcc agtatatcat gatacactcg ctgatttatc ggacagattt
    38341 gttgcgtgct agccagttct aactgcctga acatactttt tatgtcgatg atctctttgt
    38401 ctttacgccc cttcagcagg tcaagaccat gtactatctg cctgtcgatt tctatcgtta
    38461 tttgattggg cgtgaggacc agtctgtcaa tgagcaagtg atgattaagc gcattgacca
    38521 gcaactcaag gtcaatcgac tcttggtaga ccagcttgat ttgtcccaag tgagtcatcc
    38581 taaaatgcga gaatatctgc tgaatcatat tgaaatcacg acggtgattt ccagtaccct
    38641 gctcaaccga tctgaaacag cggagcatct ggcaaaaaaa cgccaattgt ggacctatat
    38701 tcagcagaaa aatccagaag tctttcaggc tattcgtaag accatgttga gccgtttgac
    38761 caaacattct gtcttgccag atcgcaaact gtccaatgtc gtctatcaaa tcaccaaatc
    38821 tgtttatgga tttaattaat ataagtgttt tataagaggg atttaagaaa aattttaact
    38881 ttttcttagt cctttttaat ttcaggagat tatactagag tcatcaaata aagaaagact
    38941 ctaaggagaa tcctatgaaa ttcaatccaa atcaaagata tactcgttgg tctattcgcc
    39001 gtctcagtgt cggtgttgcc tcagttgttg tggctagtgg cttctttgtc ctagttggtc
    39061 agccaagttc tgtacgtgcc gatgtggtca atccgacccc aggtcaagtc ttacctgaag
    39121 agacatcggg aacgaaagag ggtgacttat cagaaaaacc aggagacacc gttctcactc
    39181 aagcgaaacc tgagggcgtt actggaaata cgaattcact tccgacacct acagaaagaa
    39241 ctgaagtgag cgaggaaaca aactcttcta gtctggatac actttttgaa aaagatgaag
    39301 aagctcaaaa aaatccagag ctaacagatg tcttaaaaga aactgtagat acagctgatg
    39361 tggatgggac acaagcaagt ccagcagaaa ctactcctga acaagtaaaa ggtggagtga
    39421 aagaaaatac aaaagacagc atcgatgttc ctgctgctta tcttgaaaaa gctgaaggga
    39481 aaggtccttt cactgccggt gtaaaccaag taattcctta tgaactattc gctggtgatg
    39541 gtatgttaac tcgtctatta ctaaaagctt cggataatgc tccttggtct gacaatggta
    39601 ctgctaaaaa tcctgcttta cctcctcttg aaggattaac aaaagggaaa tacttctatg
    39661 aagtagactt aaatggcaat actgttggta aacaaggtca agctttaatt gatcaacttc
    39721 gctctaatgg tactcaaact tataaagcta ctgttaaagt ttacggaaat aaagacggta
    39781 aagctgactt gactaatcta gttgctacta aaaatgtaga catcaacatc aatggattag
    39841 ttgctaaaga aactgtcgaa aaagctgtta aaga
//
LOCUS       DAVLMQ010000015        39310 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000015 DAVLMQ010000000
VERSION     DAVLMQ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 39310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39310
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.015"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..365)
                     /locus_tag="VXF95_000921"
     CDS             complement(<1..365)
                     /locus_tag="VXF95_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1081490.1"
                     /translation="MEQLHFITKLLDIKDTNIQIIDVVNRDSHKEIIAKLDYDAPSCP
                     ECGNQLKKYDFQKPSKIPYLETTGMPTRILLRKRRFKCYHCSKMMVAETSIVKKNHQI
                     PRIINQKIAQKLIEKISMT"
     gene            939..1457
                     /locus_tag="VXF95_000922"
     CDS             939..1457
                     /locus_tag="VXF95_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HEV1081491.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEAGEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            1587..2093
                     /locus_tag="VXF95_000923"
     CDS             1587..2093
                     /locus_tag="VXF95_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HEV1081492.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEV"
     gene            2093..2263
                     /locus_tag="VXF95_000924"
     CDS             2093..2263
                     /locus_tag="VXF95_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000442275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081493.1"
                     /translation="MERSLFGLFTAFLCFICFLAGAQAFRKKRYGLSILLWLNAFTNL
                     VNSIHAFYMTLF"
     gene            2295..3527
                     /gene="clpX"
                     /locus_tag="VXF95_000925"
     CDS             2295..3527
                     /gene="clpX"
                     /locus_tag="VXF95_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HEV1081494.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            3536..4123
                     /locus_tag="VXF95_000926"
     CDS             3536..4123
                     /locus_tag="VXF95_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HEV1081495.1"
                     /translation="MELNTHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            4134..4514
                     /locus_tag="VXF95_000927"
     CDS             4134..4514
                     /locus_tag="VXF95_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HEV1081496.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            4566..5456
                     /gene="rapZ"
                     /locus_tag="VXF95_000928"
     CDS             4566..5456
                     /gene="rapZ"
                     /locus_tag="VXF95_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HEV1081497.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            5453..6430
                     /locus_tag="VXF95_000929"
     CDS             5453..6430
                     /locus_tag="VXF95_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HEV1081498.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVAGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQEYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            6427..7338
                     /gene="whiA"
                     /locus_tag="VXF95_000930"
     CDS             6427..7338
                     /gene="whiA"
                     /locus_tag="VXF95_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HEV1081499.1"
                     /translation="MSFTVAVKEEILGQHHLSWHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(7426..8553)
                     /locus_tag="VXF95_000931"
     CDS             complement(7426..8553)
                     /locus_tag="VXF95_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1081500.1"
                     /translation="MWMEELPNGKYKFFERYKDPYTEKLKKVSVTMEKKTPQARNQAA
                     ILLQEKINKKLSTKQVESITFEEIYNLFYKSWAQTVKESTKHNCKSVDKKMKEVIPSD
                     TILANLDRRFLQEAIEKIIESNGYITAKKVRHRLRGIFNYAVQYSYIENNEVDYTTIP
                     QKPKTLEELEKKRNNFLTMQEIKALVDVLNRREYHQKYADMVLVLTLTGMRYGELTAL
                     QLKNIDFENNKIEITGNFDSVNKIKTLPKTTNSIRTIKVSESVIEAIQRQIVRLSERF
                     QPLSSDDYIFCFEKWNQPTTIACFIQILKKYGKQAKIEKNLSSHIFRHSHISFLAESG
                     LPIKSIMDRVGHSNAKMTLEIYSHTTEDMEDKLVNKLDTIF"
     gene            complement(8670..9185)
                     /locus_tag="VXF95_000932"
     CDS             complement(8670..9185)
                     /locus_tag="VXF95_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081501.1"
                     /translation="MKRIFSISSVLLCALVISTACTNQTQKSSSEPTTQASSSDDISV
                     EEYFDKLLTKVDKVTKDNYKSDDYKIYDYKTVLREPEKFFSLKMRIDNLEIVQIFKEG
                     KYTKMLVTQPSGDFYMLFMETKRIEKRFLEKDHLTVNGRYLLSYEYTTNSNKEKSVPL
                     IYVDAYLLLKN"
     gene            complement(9203..9583)
                     /locus_tag="VXF95_000933"
     CDS             complement(9203..9583)
                     /locus_tag="VXF95_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1081502.1"
                     /translation="MTEKEFSQNLGIDIEIFEDGLFPDEAFYIPALKTMFLSDAISDE
                     KRVQVALHEIGHRNHAPDTYQLFREKCELEANRNMIHHLMKAELGIAEDATTFNYLVF
                     MEKYNLKTIADEIMVKEEYLALLN"
     gene            complement(9605..9967)
                     /locus_tag="VXF95_000934"
     CDS             complement(9605..9967)
                     /locus_tag="VXF95_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1081503.1"
                     /translation="MFETFEKIKSLAKKQGISLNTLEDRVGLGKNYIYSLKNKKTPSA
                     EHISKIADYFNVSTDYLLGRTDNPTIANKKEQFFFEGKEVDVEELASTAMRFNGKPLT
                     EEDKKAIQNIIEIYLRKQ"
     gene            10264..10455
                     /locus_tag="VXF95_000935"
     CDS             10264..10455
                     /locus_tag="VXF95_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1081504.1"
                     /translation="MPDITNGREKVNDFLKDKGIKKTSLAIAYGFKRQEVTNILSGTT
                     KGPRANSFILQVIEDYGIE"
     gene            10467..11174
                     /locus_tag="VXF95_000936"
     CDS             10467..11174
                     /locus_tag="VXF95_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001006505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HEV1081505.1"
                     /translation="MNEVIKVTVNDNHEPIVSGRQLHEALGVKTEYKKWFSRMTEYGF
                     NENEDFLKVTQKCLTSSTGQNTTDHIIKLDMAKEIAMIQRTERGKQVRQYFIQVEKDF
                     NSPEKIMARALLMADQKVHKLEAQIEADKPKVLFADAVSASHTSILVGELAKLISQNG
                     YKIGANRLFSWMRENGYLIKRKGSDWNMPTQRSMDLKLFEIKETNVQHADGHITVNKT
                     PKVTGKGQQYFIDKFLN"
     gene            11360..11701
                     /locus_tag="VXF95_000937"
     CDS             11360..11701
                     /locus_tag="VXF95_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000989840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HEV1081506.1"
                     /translation="MMVVLANHPNWQVYPDEIAKRKGVNRKTIDKYFKIFEEAGYLRK
                     IRKKPPGNGGSHIFRFFSDVKISDFQFDIMKQRLNLSIKRASMNYNSDIPKSEMSESE
                     MSESEMSDFGH"
     gene            11858..12124
                     /locus_tag="VXF95_000938"
     CDS             11858..12124
                     /locus_tag="VXF95_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081507.1"
                     /translation="METVQIVRIKDVIIEKISANDEELERIFGCSKRQAGDMRREMKK
                     LPSQQKYLRNDGQLVTIKGFDAYLQYRGSQSWKKEMAKTVKMTR"
     gene            12208..12660
                     /locus_tag="VXF95_000939"
     CDS             12208..12660
                     /locus_tag="VXF95_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081508.1"
                     /translation="MPNWAEGTLKLRGRRENVASALKEMLLGDEGATLEEEYDGTLLR
                     FKNEYDYFYINGTRRAFISSKDIEIWLDDDFVIIELEDFEQAWAALADNYTEISSKFD
                     VDIKIFTFEMGMEFTQEIEISKGEIIKNIVNENFTNYSWDVPFSRLGG"
     gene            12666..13367
                     /locus_tag="VXF95_000940"
     CDS             12666..13367
                     /locus_tag="VXF95_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HEV1081509.1"
                     /translation="MADLTFAELQRKMQIEKQTKQGVKYPFRTAEDINNKFKSLDSGW
                     SVSFPEDDIIQKGDKLYYKAVAVAKRESDGTIEKAIGWAREEDVPIFHTQKGDVKQMQ
                     DPQWTGAVGSYARKYALQGLFAIGGEDVDEYPVEESQEQGQNNQQQKPNNQQAQGQNQ
                     VRYIDNIQYQEINDLINDIAKIKGMPFDTLANYVLSEKLKGLQDFHRVQVGDYEVLKN
                     YLTEQLAKAKAKRGN"
     gene            13370..14362
                     /locus_tag="VXF95_000941"
     CDS             13370..14362
                     /locus_tag="VXF95_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1351 domain-containing protein"
                     /protein_id="HEV1081510.1"
                     /translation="MVKDVTNSLTEIKVDFQPAVINVDREAIEAQVAAAIAQYSGREV
                     TVDNYKEVYEERTRFNKLIGGLDTQRKDFNRQINEPAKDFDKWVKEKVIKPIEGVTDA
                     MSAGLNAIDEHERLMRVDVVRATFEDKCMVAGIEKSTFADKYDEYSLKKYFKTGKYEL
                     KKTTLDEMDGLVLSEFDALEEYKANKQAIQEQAQEYDLPADSYIRHLEDGKSLVDILK
                     MMKTDRDAEIARKEQKEAQEKAKAERLEEIAQSAKKNANANIKAYDAETGEILEQGTI
                     TPEPQNNAREVAKFEPSEPLVKLVRLELHGGLEQWENTQEYFEDNFIGFETLED"
     gene            14384..14560
                     /locus_tag="VXF95_000942"
     CDS             14384..14560
                     /locus_tag="VXF95_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081511.1"
                     /translation="MRCFYVSGKIADLDLGSEINAENSFMAAIEFVKRYTGLLKFGSN
                     EIKVSEVEEVQNDK"
     gene            14550..15095
                     /gene="ssb"
                     /locus_tag="VXF95_000943"
     CDS             14550..15095
                     /gene="ssb"
                     /locus_tag="VXF95_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1081512.1"
                     /translation="MINNVVLVGRLTRDAELRYTQSNIAVATFTLAVNRPFKNEAGER
                     EADFINCVIWRQSAENLVNWAKKGSLIGVTGVIQTRSYDNQQGQRVYVTEVVASNFQL
                     LESRNSQQNNQGHQDHHGGYQQQGYSNQGSSFQNGNSYGQQGSFLEGNTTNLVPDFTR
                     DNNPFGRPTNPLDISDDDLPF"
     gene            15121..16260
                     /locus_tag="VXF95_000944"
     CDS             15121..16260
                     /locus_tag="VXF95_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1081513.1"
                     /translation="MKFLDLFAGIGGFRIGMESAGHECIGFCEIDKFARASYKAIHDT
                     KGEIELHDITTVSDDTIRGIGHVDVICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILKPRYLFLENVKGLLNHDRGNTFEVILSALDELGYDVEWQVLNSKDFGVPQNRER
                     VFIIGHSRKRGTRRVFPIGRANREFDFEPKIKIVGNTKNPNGTSQGTGSVVYDSNGLV
                     GTLCARDYKEPKQVAIPVLTPDRVNKRQNGRRLKKNGEPMFTLTAQDRHGILIKEATK
                     KGYAEATVGDSVNLSHPNSKTRRGRVGNQIANTLLTGESQGVVEPDFRIRKLTPRECW
                     RLQGFPDWAFDKAQEVNSNSQLYKQAGNSVTVNVISAIAQGLGGN"
     gene            16295..16498
                     /locus_tag="VXF95_000945"
     CDS             16295..16498
                     /locus_tag="VXF95_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081514.1"
                     /translation="MTKIEIVMVLTTLMSITWAAIVTIHTMQAIKKHKAKVDYYQKPQ
                     VQCEIARHVLKNKWYSDGGEVFR"
     gene            16552..16986
                     /locus_tag="VXF95_000946"
     CDS             16552..16986
                     /locus_tag="VXF95_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081515.1"
                     /translation="MDKKLIGLDLTHIADGGLQEKLDKELEKVFDNILDLNTDAKAKR
                     KVTITLTMSANEERTVVDTTMEVKSKFAPQNGVATTILIGRDFDTGQVHANELKSTVP
                     GQMYFDENGEILTDIGQPVAEIEQQAETKPDIIDFNKKKVGN"
     gene            16988..17725
                     /locus_tag="VXF95_000947"
     CDS             16988..17725
                     /locus_tag="VXF95_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014736105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081516.1"
                     /translation="MTTENLKAALEYAVELNEHGLEILTAADGTEYYDANKFNLKELD
                     PKRYPKTLELSTLTSLVDYLKTDLNNLKNQRLIVAVEKNDEVCVWSENDELERRTLLV
                     DVKARIPELSFGRFLSSEQFNIMLQSNFIDDNDRGTLLEFASALKIENGAEIEDNGVS
                     QVATVKTGVASLAKGKAPNPVTLRPYRTFSEVEQPASLFVFRIDKQANMALFEADGKR
                     WVADAVGNIAAYLKEQLADQKLITVLA"
     gene            17742..17954
                     /locus_tag="VXF95_000948"
     CDS             17742..17954
                     /locus_tag="VXF95_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081517.1"
                     /translation="MSDYKQRMIEEYKQLKERTNKLSLMISNYYVGTLDFKLKCPIEL
                     LETQHYTMCAYLKILEQRAEIENIEF"
     gene            17965..18366
                     /locus_tag="VXF95_000949"
     CDS             17965..18366
                     /locus_tag="VXF95_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000667208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081518.1"
                     /translation="MKFEFSLPRNTKLKSLNMVINSNDRQHQTDKAKVTKRIRAFAYW
                     HTSMNKDKGRAAFSPSNPCEVTVTIYSPTKSKLDPPNLYPTVKAIIDGMTDAGIWTDD
                     NHKVIKKLSFVYGGLSEEKGHYRLEFDIEEV"
     gene            18368..18574
                     /locus_tag="VXF95_000950"
     CDS             18368..18574
                     /locus_tag="VXF95_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081519.1"
                     /translation="MIEVNIKFDNFEAHGFYQDDTKLGKIRDAIISQMNNGHVVILGE
                     DRSILLNPKVIKCVQFEVVEDDQI"
     gene            18624..18938
                     /locus_tag="VXF95_000951"
     CDS             18624..18938
                     /locus_tag="VXF95_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081520.1"
                     /translation="MEELKKKVNEVYNWTVEDGKPKPPKQDLPQAVKDRVDYFWEMAE
                     DGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWIGYAPSMAQVVIAVYLIYG
                     GN"
     gene            18940..19440
                     /locus_tag="VXF95_000952"
     CDS             18940..19440
                     /locus_tag="VXF95_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1081521.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPE
                     KVKVPQFMADWIDYFKKNGDWDLFQAMDYLFGKKEIREWLEYKNNQDLFARAWLDGYE
                     VEKEKRYLVTLKNRQPLVKSQSGSTLYFSQDITARNYKGTQKELEDAKFGWVFDCPGI
                     EIEEVE"
     gene            19440..19733
                     /locus_tag="VXF95_000953"
     CDS             19440..19733
                     /locus_tag="VXF95_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081522.1"
                     /translation="MTQTLEEGMKNQSKCIKIPMEIRPFDVGYRIVNKHGQALALKNG
                     ASIFDLPSLAEKAIKKEFSKDDPDFDIEKHFVEEVAIVNLSKFHSYFEEVIHD"
     gene            19733..20125
                     /locus_tag="VXF95_000954"
     CDS             19733..20125
                     /locus_tag="VXF95_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081523.1"
                     /translation="MTKKKIERLSVIHRREINWLKWYFLRDKKNPKRTILEQKIIVSH
                     IKTDRLEAKFLSNLKKSTEDFIDKSDPKYLRAIKEVYVYENMNVIGACQKILFYSPTQ
                     AYVLLNAWFNDYFRATYTELLENAILDK"
     gene            20191..21285
                     /locus_tag="VXF95_000955"
     CDS             20191..21285
                     /locus_tag="VXF95_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000425577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4417 domain-containing protein"
                     /protein_id="HEV1081524.1"
                     /translation="MEMLQIEYVDIKSIKPYHKNARHNDGEATEKVAASIKAFGFQQP
                     ILVDDNNIIITGHTRLKAALSLGIDTIPIAHAVNLTDEQIKAYRLADNRVAEYSTWDS
                     ELLNIELSQFETIDMAQFGFELSVTGFNFGNEEEQQEETENEEEDAEDFHRDTTINQY
                     NLFNYDDTRVEGFYNMPKIEGVDHIPKDFQGFNYVLNKPDYSSCVHFFLDDYQFERIW
                     QRPDFYIEKLLEFDSALAPDFSLYLDMPIAMQVWNIYRSRLIGQIMQDYGLTVIPTVS
                     WASEESFDFCFDGLPKNSTLAISTIGVKQNKEQFEVWKNGVTEMIKRLTPKRIVVYGG
                     KVEYDYKDIEVVYFENATTERMKESGTKTN"
     gene            21266..22012
                     /locus_tag="VXF95_000956"
     CDS             21266..22012
                     /locus_tag="VXF95_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081525.1"
                     /translation="MAQKLTKLKDIFKHVSSIDLGKEILFEDLELYNKETETSKQYQS
                     IEEAENDLSLMEKVNKINFTLGGGRGANFEKGKDGKYPGFRGAGGARDSGSSKALHPA
                     SLNNQGRFSSVEGAIQGFIKKHGGSRTEYSTAVDSQGFAHNYVHGGKNSVQILPISGG
                     FTAIHNHPNGSNFSSTDLHSFAALKGMNTLVATNSSKAYRITKGANFDAKGFDKAVSK
                     SRFTTKDYNKGADLWLKKNAKKYGYTYSYE"
     gene            22216..22671
                     /locus_tag="VXF95_000957"
     CDS             22216..22671
                     /locus_tag="VXF95_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein"
                     /protein_id="HEV1081526.1"
                     /translation="MPRDGTKNLKPVTERTKDEARAISSKGGKASGIARRKKADLKKA
                     FETLLSLDVTDSKIKKQLEEMGMAGNNEALLAFATFQQAVKGNQKATENIIKLTNTKD
                     KYDIQEQKERIKALKYENRERAEAEKGSSETIEIVDAWAEDVRGATDDL"
     gene            22661..23971
                     /locus_tag="VXF95_000958"
     CDS             22661..23971
                     /locus_tag="VXF95_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBSX family phage terminase large subunit"
                     /protein_id="HEV1081527.1"
                     /translation="MTFNVQKNINPHFKSVWISSLPYNVLKGGRNSFKSSVIVLKLAY
                     MMIRYIIAGEAANIVVIRKVANTIRDSVFNKVWWALNLFGIAEQFTKTVSPFKIVHKT
                     TGSTFYFYGQDDFQKLKSNDIGNIIAVWYEEAAEFNDQEDFDQSNVTFMRQKHPRAKF
                     VQFFWSYNPPRNPYSWINEWFESIKTNKNYLAHSSTYLDDELGFVTEQMLEDIERIKE
                     NDYDYYRYLYLGEAVGLGNNVYNMSMFHAIDALPSDDKLIGISFALDGGHQQSATACC
                     AFGITAKGKVILLDTWYYSPAGQVVKKAPSQLSKEIYTYIRSVIEKYRVQALQYTIDS
                     AEGALRNQMFLDFGLKWHPVAKLRKVTMIDSFQSLLAQGRFYYLNTENNKIFIEEHKM
                     YRWDEKTIKSDNPSVIKEDDHTCDTTQYFVLDNAKLLGLRVGNV"
     gene            23984..25552
                     /locus_tag="VXF95_000959"
     CDS             23984..25552
                     /locus_tag="VXF95_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1081528.1"
                     /translation="MSLFQKVKDFFSRGRYYMQTSNLNSILEHPKIAVTQEEYDRIKR
                     NLVYYQSKWDDVQYKNTDGDIKSRPMNHLPIARTASKKIASLVYNEQATITTKNEILQ
                     KFLDDMLTNDRFNKNFERYLESCLALGGLAMRPYIDGDKVRVAFIQAPVFFPLESNTQ
                     DVSSAAILTKTIKSEGRKNVYYTLVEFHEWVTADGQETGSTNDKKYYRITNELYRSDV
                     NDVLGQRVNLSELDKYKNLEPVTVFENLSRPLFTYLKTPGMNNKDINSPLGLSIFDNA
                     KTTIDFINRSYDEFMWEVRMGQRRVIVPEHLTQRQYQRPDGTIDFRPRFDVEQNVYMQ
                     IGGSSMDAGGITDLTSPIRANDYILAISEGLKLFEMQIGVSSGMFTFDGQGMKTATEI
                     VSENSDTYQMRSSIVALVEQSIKELCVSMCELGKAVGVYSGEIPELDDISVNLDDGVF
                     TDRHAELDYWAKMVAAGFSTKKRAIGKTLNISGVEAEKELNAINSELLPMNDAELAIY
                     GMHDQNEEEADDKG"
     gene            25539..25712
                     /locus_tag="VXF95_000960"
     CDS             25539..25712
                     /locus_tag="VXF95_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081529.1"
                     /translation="MTKVKFGVTSVDYSASIEDTPTIKLGLIIRGSGRLDASSVIKKL
                     IKDVSELEYELEE"
     gene            25755..26906
                     /locus_tag="VXF95_000961"
     CDS             25755..26906
                     /locus_tag="VXF95_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor capsid protein"
                     /protein_id="HEV1081530.1"
                     /translation="MKKKRKQITFNDQQFPLQMQGVGDIYEKLQIDIFDRMIKRLKER
                     GSIDLMRNPYIWQLEKLNDMHMLNEQNLKLISERTGIAERLLRDVIENEGLKVYKDTK
                     QQLEEDLNKIPEGEISNGVTDSLEAYSRQAVSDLNLINTTLPKSLQVAYKSIVEETVA
                     QVVAGTKTSDVALHDTIMKWQKNAFTGFVDKGGRHWKADSYARAIIKSTTYKVYNEMR
                     TRPAEELGVDTFYYSMKAMARPACSPLQGQIVTKGAGRKIDGITIYSLLDYGYGTAAG
                     CLGIHCGHYLTPFIVGVHELPNLPDYLKNLTPEQAEENARIEAGQRGLERLIKTHKER
                     LHYAHTLQDDKMIQAERLKVRGYQTKIRNLINQHDFLTRDYRREKLYIS"
     gene            27045..27608
                     /locus_tag="VXF95_000962"
     CDS             27045..27608
                     /locus_tag="VXF95_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage scaffolding protein"
                     /protein_id="HEV1081531.1"
                     /translation="MAFTTEELLNLGLTEEQAKSVFALRGKELNEDKSALETIKQERD
                     SLKSQLQKAEEQVEHLKSLENISAEQKDAIDKLQAEYDKYKNEAAAELAQTKKVSAIS
                     LALKDTNAFNPDKLMKFIDVDAIQLDDNGKPQIDEVINGLKESDPYLFKAEESKPSPN
                     ILPQGNPAGEGTSDVDPFQAIIDGYGK"
     gene            27626..28507
                     /locus_tag="VXF95_000963"
     CDS             27626..28507
                     /locus_tag="VXF95_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage capsid protein"
                     /protein_id="HEV1081532.1"
                     /translation="MPSNQNNAVRRYEKQYAGILETVFRVRAAFSNALASIQILDGVQ
                     ENSKAFSVKTNNTPVVIGEYKTGENDGDFGDNSGAQSRFGGLTEVKYENTDVNYDYTL
                     TIHEGLDRYTVNNDLNAAVADRLKLQSEAQTRTVNKRIGKYLSDNATNTEALADFTDD
                     KVKALFNKLSAFYTNNEVTAPITVYLRSEFYNAIVDMASVTSAKGATISLDENGLPKY
                     KGFTLEETPAQYFETGVIAIFSPNGIVIPFVGISTARVIEAENFDGVKLQAAAKGGTY
                     TLDDNKKAIYKVTGTIV"
     gene            28518..28751
                     /locus_tag="VXF95_000964"
     CDS             28518..28751
                     /locus_tag="VXF95_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001240344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081533.1"
                     /translation="MAIYKATKNLFFEQLNMDVIVNDIIELDEDYAKEVNKKLKNAFP
                     DVKNVLELVDKNGTLEPEDAPSVDDASQATVED"
     gene            28794..29186
                     /locus_tag="VXF95_000965"
     CDS             28794..29186
                     /locus_tag="VXF95_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013794407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081534.1"
                     /translation="MTYLTQEEFDELDFDEVTDFEKLAKRAKIAIDLYTNGIYQKDID
                     FEKEIAYRKSAVKLAMAFQIAYLDASGIMSADDKQLANSVSIGRTSISYSTSQSTLAG
                     QRFNLSMDAENALRQAGFSLVVGVAYDR"
     gene            29176..29547
                     /locus_tag="VXF95_000966"
     CDS             29176..29547
                     /locus_tag="VXF95_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1081535.1"
                     /translation="MIDKRLLKGIDKRLLKDVLTIKKVADKNDYGDEVYSEPLTIKNV
                     RFDRSVGGSGNRNSKTGTGNSKSRQKQGVIYLYPSLSFVTVDNSWMGAKVNDGIGDYT
                     INGFQTNYYDGEIFSQEIEVI"
     gene            29547..29891
                     /locus_tag="VXF95_000967"
     CDS             29547..29891
                     /locus_tag="VXF95_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1081536.1"
                     /translation="MNIAIKVDLQKAKQKLSNESMTRGKIAVASKILLDNEQYIPLRG
                     GELRASGRIVGQGDAVVYGTVYARAQFYGANGIVTFRRYTTPGTGKRWDQVATSKHAE
                     EWARAFVKGMGL"
     gene            29891..30298
                     /locus_tag="VXF95_000968"
     CDS             29891..30298
                     /locus_tag="VXF95_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsid protein"
                     /protein_id="HEV1081537.1"
                     /translation="MRENDFQNVLLKHIKTLNLPVEPRFDYFEDDKDDLVINQIPGGK
                     VDREYMDGTQEVSLPFEIAVKAKKNSVANDTIWLVTSELAKIDLVLPSDNNSYEYMGM
                     EVSRPAMKGKDEQGYYYYTIEIVAKIVIERNKQ"
     gene            30295..30744
                     /locus_tag="VXF95_000969"
     CDS             30295..30744
                     /locus_tag="VXF95_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1081538.1"
                     /translation="MTRQKNALRGHFVAPYNGGTEPTTEDTWLELAKWISDVSDDTDE
                     KTDDQAYYDGDGVEETTVVSVKGAYTFEGTYDPDDKAQALIAGMKYKTGDDRKLWHKV
                     VSSDKKKQWVGAATATEIKAGSGAASDYEVFGCKLSYNSTPKETGIG"
     gene            30809..31297
                     /locus_tag="VXF95_000970"
     CDS             30809..31297
                     /locus_tag="VXF95_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000129842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081539.1"
                     /translation="MTDIQIELKRTGFPVKIGEVELWFDTSQESLMRFYDMEEELKRR
                     LVQYELDVVSANINNKIERDGVTKEVVAGAIELEKKQLEIQYDLIFGDGTFDKLYSIY
                     PDYNALNNALEQTAIMLHDKLEELAEQHKTVVKERASHYLNKGKVTPIKNNKKQKKNK
                     KK"
     gene            31310..31879
                     /locus_tag="VXF95_000971"
     CDS             31310..31879
                     /locus_tag="VXF95_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081540.1"
                     /translation="MSMKLNDALITNFSIADKEYDIDLSFNKVLDVFEILKEDEMTRL
                     EQAQLIVHLLTGQELYDIKEVVDCWIYIKEHFLGIEKETVQYDLLGNPMPKAKGEEEQ
                     EKLIDFEQDAEYIYASFLQAYGINLLKVQNELTWTEFKALLNALPDNTIMQQIIEIRA
                     WKPEYGGDKNKMRKLQAKYSLGKEGEDNV"
     gene            31872..35153
                     /locus_tag="VXF95_000972"
     CDS             31872..35153
                     /locus_tag="VXF95_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HEV1081541.1"
                     /translation="MSDGKVTIVVDVDGNKVKVLNDELDKTAQKGDRGSSSLKKFAVG
                     SAVFQLAAKGAELLGEALGGAIQRFDTLESYPRVMQAMGHSTEDVTRSTKKLAAGIEG
                     LPTTLNEVVGTAQRLTSITGDINKSTDLTLALNNAFLASGSSSADASRGLQQFSQMLS
                     AGKVDMQSWKTLQETMPYALQKTAESFGFAGQSAQNDFYSALKEGRITFNQFSSKLVE
                     LNGGVGGFAELAKTNSKGIQTSFGNLKNAVVKGVANTIKALDDLTKAATGKTIAENFD
                     ALKVIINAAFGVIVNVIKASTPVFQTLFSILGTGASVISFLTPAIIGLVAALVTMRAI
                     NQAVKTTKDLISAWKTFKTTATGAIQIINLMTAAQATCGSVTKAQLVANLANNGALTA
                     SNLLYGVLTGSISLQTAATIAATAATTAFKAALTALTGPIGLVVAGIGLVVGVCVTLW
                     QWLTAESEETKRLKSEQEELVKSTDQLTDSVKQSAKERQKNLESVKGNTESYQKLADE
                     IVQLSQKTNKTAADKKNLKKKIDALNASVSGLNLAYDKNSDSLSHNSDQIKARISAME
                     AESTWETSQKNLLDIEQKRAEIGEQLKKIAEQRKKWNEESNVSDSVRKERLQELNDKE
                     TELKNTQTELQTEYEKTSQVQQAASEAMAAAAENGSNRQVVAYENMSKSQQKAIDDMR
                     TKYNELLETTTNMFEQIKYKSAISVDEMIANLQKNQEAVNNWATNLNTLAERGVNEGI
                     LAKLQAMGPQGGLYVQELVNASDEKLATLNEVFTQGGESAMNGLTAGMDTGALGITDK
                     IKGIVQSQVSSLQEEIAAADFSSLGQEIPNGVSQGIEQGVSTAGESSKNMANDIKESF
                     TSEMDINSPSRVFNEYGGFITTGLAEGVDKGTNQPVSSVTNLANQIKKPFDSLQSDFT
                     YIGEMAMSGLNAGLWSGSGSVMATANSIAERVKATIKSALDIHSPSRAMRDEVGRFIP
                     QGIAVGIEADAGVVEKSMLRLKESMMIDTRPEIALGLNKKLGAQVTVKQSSKQTIAEK
                     IKVTMDKSSELLEKALDVAETAVRRPNEMYLNDGTLVARTGDKFAKYQSEQLRRDNRM
                     KGVLS"
     gene            35150..36664
                     /locus_tag="VXF95_000973"
     CDS             35150..36664
                     /locus_tag="VXF95_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail family protein"
                     /protein_id="HEV1081542.1"
                     /translation="MTKIMTFNGVDMSKFFRITDIIRPIGNKRSVSTDNAPLLGVNIQ
                     QVKIGEKEHIIKFDIKTTNAIEMEQLKHDLAGILNVLEPVKITYGDEPDKYYMGLPVD
                     EITPENLTRWFQRSELKIIIPDGVAHSTTLKNFDIDTNETSAPDRIVFNLTNTGTEPA
                     YPIIRIKHNSENGYIGVVNNRAAFELGNREEADTEKYRDSETLIDYRGTNILKGFQNG
                     TKGVAVTNDNKERLVGTLSTTSMWGRNHIELSNRGTVEKNRNNAQSLTWAIPVDSSGE
                     VGSLNDYLLWRQVFMAAVANQYGFIKVTVSDTDGNFLYGVETYKRYQTLDCEYSFFTT
                     DGKGGYKFIKWWYFTGTGAQVGKLDPFSAEKGWSELKRNDDRVQVFFDGSHYDFIIPE
                     IKDKKSAKIHITLGALRDWPLISHMYVDEFMYRKDFVTKSRDIPNRYPIGSNVVINSE
                     DDSVYIDGISKVSEVVDGSHWPAIPPGKSQLELYFSRFVKKKPTVTIEFEERWI"
     gene            36666..>39310
                     /locus_tag="VXF95_000974"
     CDS             36666..>39310
                     /locus_tag="VXF95_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1081543.1"
                     /translation="MLLTIHDANLQKVAFIDNEKQGTLNYYDDTWTRSLATGSSTFEF
                     TVFKKAVKSDLPLAKAYHHLNEHAFVSFKYKGKSFVFNIIIVEENEQTIKCYCENLNL
                     ELINELANPYKSNKAMTFKEYCEAMDLLNYTHLSIGINEISDYKRTLEWEGQETKLAR
                     LLSLAKRFDAEIEFDTQLNADSTIKKFSVNVYHENDDNHQGVGRVRNDVIVKYGKNIH
                     SITRKVDKTGIFNTIRPTGKMPTVEEEPSGDKGSKSETVKNADGSTTKTTISTASDGT
                     KSKTIVHTKVTKLADKTRITTTTTTRSDGSIEQTVTTSKKGGASTSETKVLKKPNPKE
                     KTNTTEDVLTIEGLDEWEVKNEKGIVEFYQRGQALYAPISMQLYPSTFTHSTGELDQW
                     TRKDFHFETDEPNELRRLGYLKLKKYCYPAITYEVDGFVDADIGDTVKVHDDGFAPLL
                     MIQARVTDQKISFTNPVRNKTIFDNFKALENKLSADIQSAFERLFEAAKPYTIKLSTD
                     NGVIFKNQIGQSLVTPTLYKGGKPVVVGVTWRWALDGEVTTGMTYLVRGSNVTDTVTL
                     TVAAYIGNKEVAVDEISLVNVADGKLGTPGTPGRDGRTPYVHTAWANNATGTDGFSLD
                     SSINKLYIGIYTDFEPNDSTDPKKYKWAKVKGDKGEKGDKGEPGQRGLDGLQGARGEQ
                     GLPGRNGADGRTQYTHIAYSNSADGTKDFSVSASDRAYIGMYVDFNSADSNTPSDYNW
                     TLVKGADGANGVAGKAGTDGRTPYLHIAYATSNNGSQGFSTTDSTNKTYIGTYTDYTQ
                     ADSTDYRVYKWTLIKGADGTGISNVTNYYLATTVSTGITRTSAGWTTTPQPITSDKRY
                     LWNYRVELYTNGTSKTTEPTVIGVHG"
BASE COUNT        13203 a         6618 c         8626 g        10863 t
ORIGIN      
        1 tcagtcatag aaatcttttc aattaacttt tgagcaatct tttggttgat gatacgaggg
       61 atttggtgat tcttcttgac gatagaagtt tcagcaacca tcatttttga acagtgatag
      121 cacttgaatc gacgctttct aaggagaatt ctagtaggca taccagtcgt ttcaagataa
      181 ggaattttag aaggtttttg aaagtcatat ttcttcaatt ggtttccgca ctcagggcaa
      241 gatggggcgt cgtagtccag tttggcgatg atttccttgt gtgaatccct attgacgaca
      301 tctataattt ggatatttgt gtctttgata tcgagtagtt ttgtgataaa atgtaattgt
      361 tccatatgaa tctttctaat gagttgtttg gtcgcttttc attatagatc ttatgggact
      421 ttttttctac aataaaatag gctccataat atctatagtg gatttaccca ctacaaatat
      481 tatagagtcg ttttatgata gttcatcctc gagtaaattc aagatcttgc tcggaaatga
      541 agcttatata gtagattgaa tatagacaaa gaccttgtga ttggtaaaac attttagaaa
      601 ttcatttacc tttcctaatc gacttggttt catcttattt caatctatta tagtattggg
      661 gaatttcttc aaaccacatc agcttggtca gttctacctg cgacctcaaa acttgtgctt
      721 tggtcaagct gggtttagtt tcctagtttg ctgatggatt tccattgact ataagcatcc
      781 aaccctcttt tttgtcttct aaagaattct taaattatca gtctattgca acttttctca
      841 tataagttct ttgtcttgct attggttttc cttagtagta tactaaggta gtaatcatta
      901 agaagtggtt acaaaaaata atgaatgagg taaagaaaat ggtagaattg aaaaaagaag
      961 cagtaaaaga cgtaacatca ttgacaaaag cagcgccagt agcattggca aaaacaaagg
     1021 aagtcttgaa ccaagctgtt gctgatttgt atgtagctca cgttgctttg caccaagtgc
     1081 actggtatat gcatggtcgt ggtttccttg tatggcatcc aaaaatggat gagtacatgg
     1141 aagctcttga cggtcaattg gatgaaatca gcgaacgctt gattacactc ggtggaagcc
     1201 cattctctac attgacagag ttccttcaaa atagtgaaat cgaagaagaa gctggtgaat
     1261 accgtaatgt tgaagaaagc ttggaacgtg ttcttgttat ctaccgttac ttgtcagaac
     1321 ttttccaaaa aggtttggat gtcactgatg aagaaggtga cgatgtgaca aacggtatct
     1381 ttgcaggcgc taaaactgaa acagataaaa caatttggat gcttgcagcc gaacttggac
     1441 aagcacctgg tttgtaagaa ataaggaaac atagataaat ctgtaggaaa tttcttacag
     1501 attttttcta ttttgtaagc tattccaaac cagtcttttt ttgagttttt tgataaaata
     1561 gtactatcag tgaaaaggat ggaagcatga ctaagaaaat cgtagctatt tgggcccagg
     1621 atgaagaggg tgtgattggt aaggaaaatc gtctgccttg gcatttgcca gcagaattgc
     1681 agcactttaa agaaacaact ctgaatcatg ctatcttgat ggggcgtgtg acctttgatg
     1741 ggatggggcg tcgcttgctt ccaaaacggg aaaccttgat tttgacgcgt aatccggaag
     1801 aaaagataga tggggttgct acttttcagg acgtccagtc tgttcttgac tggtatcagg
     1861 ctcaagaaaa gaatctctac attatcggtg ggaagcaaat ttttcaggct tttgaacctt
     1921 accttgatga agtgattgtc actcacattc atgctcgggt ggaaggagat acctatttcc
     1981 ctgaagaact tgacttgtct ctttttgaga cagtttcaag caaattttac gccaaagatg
     2041 agaagaatcc ttatgatttt accatccaat accgcaagag aaaggaagtc taatggaacg
     2101 gagtttattt ggtctattca cggcttttct gtgtttcatc tgctttctgg caggagcaca
     2161 agcttttcgt aaaaagcgtt acgggctttc tatcctcctt tggttaaatg cctttaccaa
     2221 tctggtcaat agtattcatg ctttttacat gaccttattt tagatagaat gacagtatag
     2281 aatggaagga aatcatgtct acaaatagaa aaaatgatat gatggtttat tgctcatttt
     2341 gtggcaaaaa ccaagaagaa gtacaaaaaa taattgctgg caacaatgct tttatttgta
     2401 atgaatgcgt ggagttagct caggaaatca ttcgagaaga attggttgag gaagtcttgg
     2461 cagacttgtc tgaggtgcca aaaccaattg aactcctcca tatcttgaac cactatgtaa
     2521 ttggtcaaga tcgtgccaag cgtgccttgg cagtggcggt ttataaccac tacaaacgca
     2581 tcaatttcca cgatacacgc gaagagtcag aagatgtgga tttgcagaag tcaaacattt
     2641 tgatgattgg cccaactggt tcagggaaaa ctttccttgc ccagaccttg gctaagagct
     2701 tgaatgtacc ttttgctatt gcggatgcga cagctctgac ggaggctggt tatgtgggtg
     2761 aggatgtgga aaatatcctc ctcaaactct tgcaggttgc tgactttaac atcgaacgtg
     2821 cagagcgtgg cattatctat gtggatgaaa ttgacaagat tgccaagaag agtgagaatg
     2881 tgtctatcac acgtgatgtt tctggtgaag gggtgcaaca agcccttctc aagattatcg
     2941 agggaactgt tgctagcgta ccgcctcaag gtggacgcaa acatccacaa caagagatga
     3001 ttcaagtgga tacaaaaaat atcctcttca tcgtgggtgg tgcttttgat ggtattgaag
     3061 aaattgtcaa acaacgtctg ggtgaaaaag tcatcggatt tggtcaaaac aataaggcga
     3121 ttgacgaaaa cagctcatac atgcaagaaa tcatcgctga agacattcaa aaatttggta
     3181 ttatccctga gttgattgga cgcttgcctg tttttgcggc tcttgagcaa ttgaccgttg
     3241 atgacttggt tcgcatcttg aaagagccaa gaaatgcctt ggtgaaacaa taccaaacct
     3301 tgctttctta tgatgatgtt gagttggaat ttgacgacga agcccttcaa gagattgcta
     3361 ataaagcaat cgaacggaag acaggggcgc gtggacttcg ctccatcatc gaagaaacca
     3421 tgctagatgt tatgtttgag gtgccgagtc aggaaaatgt gaaattggtt cgcatcacta
     3481 aagaaactgt cgatggaacg gataaaccga tcctagaaac agcctagagg tgactatgga
     3541 acttaataca cacaatgctg aaatcttgct cagtgcagct aataagtccc actatccgca
     3601 ggatgaactg ccagagattg ccctagcagg gcgttcaaat gttggtaaat ccagctttat
     3661 caacactatg ttgaaccgta agaatctcgc ccgtacatca ggaaaacctg gtaaaaccca
     3721 gctcctgaac ttttttaaca ttgatgacaa gatgcgcttt gtggatgtgc ctggttatgg
     3781 ctatgctcgt gtttctaaaa aggaacgtga aaagtggggg tgcatgattg aggagtactt
     3841 aacgactcgg gaaaatctcc gtgcggttgt cagtctagtt gaccttcgtc atgacccgtc
     3901 agcagatgat gtgcagatgt acgaatttct caagtattat gagattccag tcatcattgt
     3961 ggcgaccaag gcggacaaga ttcctcgtgg taaatggaac aagcatgaat cagcaatcaa
     4021 aaagaaatta aactttgacc cgagtgacga tttcatcctc ttttcatctg tcagcaaggc
     4081 agggatggat gaggcttggg atgcaatctt agaaaaattg tgaggaaaag aaaatggcaa
     4141 aaacaattca tacagataag gccccaaagg ctatcggacc ctatgttcaa ggaaaaatcg
     4201 ttggcaacct tttgtttgct agcggtcaag ttcccctatc ccctgaaact ggggaaattg
     4261 taggagagaa tatccaagaa cagacagagc aagtcttgaa aaacatcggt gctattttgg
     4321 cagaagcagg aacagacttt gaccatgttg tcaaaacaac ttgcttcttg agcgatatga
     4381 acgactttgt tccttttaat gaggtttacc aaacggcctt caaagaggaa ttcccagctc
     4441 gttcagctgt ggaggtagct cgtcttcctc gtgatgtaaa agtcgaaatt gaagtcatcg
     4501 cagagattgg ataagctagt tgaagtttgg tgttgccaaa cttcttttga tataaggaga
     4561 aaaagatgac aaagaaacaa cttcacttgg tgattgtgac agggatgagt ggcgcaggga
     4621 aaactgtagc cattcagtcc ttcgaggatc taggttattt caccattgat aatatgccgc
     4681 cagctctctt gcctaagttt ttgcagctgg ttgaaattaa ggaagataat cctaagttgg
     4741 ctttggtagt ggatatgcgt agccgttctt tcttttcaga gattcaagct gttttggatg
     4801 agttggaaaa tcaagatggt ttggatttca aaatcctctt tttggatgcg gctgataagg
     4861 aattggtcgc tcgttacaag gaaaccagac ggagtcaccc actagcagca gacggtcgta
     4921 ttttagatgg aatcaagttg gaacgtgaac tcttggcacc tttgaaaaat atgagccaaa
     4981 atgtggtgga tacgactgaa ctcactccac gtgaactgcg caaaaccctt gcagagcagt
     5041 tttcagacca agaacaagcc cagtctttcc gtatcgaagt catgtctttc ggatttaagt
     5101 atggaatccc gattgatgcg gacttggtct ttgatgtccg tttcttgcca aatccctatt
     5161 atctaccaga actgagaaac caaacgggtg tggatgaacc tgtttatgat tatgtcatga
     5221 accatcctga gtcagaagac ttttatcaac atttattggc cttgattgag ccgattctgc
     5281 caagttacca aaaggaaggt aagtccgttt tgaccattgc tatgggatgt acgggtggac
     5341 aacaccgtag tgtggcattt gctaaacgct tggcgcagga cttatccaag aattggtctg
     5401 ttaatgaagg gcatcgcgac aaagaccgca gaaaggaaac ggtaaaccgt tcatgagaaa
     5461 accaaagata acggtgattg gtggagggac tggaattccc gtcattctaa aaagtctgcg
     5521 ggaaaaagat gtggaaatcg cagctatcgt gacggtggca gatgatggtg gttcttcagg
     5581 tgaactccga aaaaatatgc aacagttgac accgccaggt gatcttcgta atgtccttgt
     5641 ggccatgtcg gatatgccta agttttatga gaaggtcttt cagtatcggt tctctgagga
     5701 tgccggagcc tttgctggcc atccattggg aaatctcatc attgctggct tgtcagaaat
     5761 gcagggttca acctataatg ccatgcagtt attgagcaaa tttttccata caacagggaa
     5821 aatttatcct tccagtgacc atcctttgac ccttcatgca gtctttcagg atgggacaga
     5881 agtggctgga gagagtcata ttgtagacca tcgaggcata attgacaatg tctatgtgac
     5941 caatgcccta aacgatgata cgcctctggc cagccgtcga gtagtgcaga ccatccttga
     6001 aagtgacatg attgtcctag ggccaggttc cctctttacc tctattttgc ccaatatcgt
     6061 gattaaggaa attgggcggg ctcttttgga aactaaggca gaaattgcct atgtctgcaa
     6121 tatcatgacc caacgtgggg agacggaaca ctttacagat agcgaccacg tggaagtctt
     6181 gcatcgtcac cttggtcgcc cttttatcga cactgtcttg gtgaatattg aaaaagtgcc
     6241 tcaggaatac atgaattcca accgttttga tgaatactta gtgcaagtgg aacacgattt
     6301 tgtaggtctt tgtaagcaag tttcgcgcgt gatttcatct aacttccttc gtctggaaaa
     6361 tggcggtgcc ttccacgatg gagatttgat tgtggacgag ttgatgcgca ttatacaggt
     6421 gaaaaaatga gtttcacagt agcagtaaaa gaagaaatcc tgggccaaca ccatctgagc
     6481 tggcatgaat tatctgccat tatcaaaatg tctggtagca tcggtctctc gacttcgggc
     6541 ttgactttgt cagttgtgac agaaaatgcc aaactggccc gtcacctcta tgagtccttt
     6601 cttcatttct atgaaatcaa atctgaaatt cgtcaccacc aacggagcaa tcttcgcaag
     6661 aatcgcgtct ataccgtttt tacagatgaa aaggtgcagg atttgttaag tgatttgcac
     6721 ttggcagact ctttctttgg cctggaaaca ggtattgatg aggcgatttt atcggatgag
     6781 gaagcaggtc gtgcctatct ctgtggcgct ttcttggcaa atgggagcat tcgtgaccct
     6841 gagtcaggca agtaccagtt ggaaatcagt tctgtttatc tggaccacgc gcaaggaatt
     6901 gcctcccttc tccaacagtt tttactggat gccaaggtgc ttgagcgcaa gaagggggct
     6961 gtgacctatc tccagcgagc agaagacatt atggacttct tgatagtaat cggagccatg
     7021 caggcacgtg atgattttga gcgggttaag attttgcgag aaacccgtaa cgacctcaat
     7081 cgggctaata atgccgagac agctaatatc gctcggacag tttctgccag catgaagacc
     7141 attaacaata tcagtaaaat caaagatatc atgggcttag aaaatttgcc agtagatttg
     7201 caggaagtgg cgcaactgag gattcagcac ccagactact ctatccagca gttagcagat
     7261 agtctcagca cccctctgac caaaagtggt gtcaatcaca gactcagaaa aatcaataag
     7321 atagcggatg aattataacg atataaagca accccttgaa ttatcaatat cttcaagggg
     7381 ttttgttgtg ttatgaaatc aaaaaggggc aaccaagggg cagaattaaa aaatagtatc
     7441 taatttattg accagtttat cctccatatc ctcagtagta tgagaataga tttccaaagt
     7501 catttttgca tttgagtgcc caactcgatc cattattgat tttattggga ggccagactc
     7561 tgctaaaaac gaaatatgag aatgcctaaa aatatggcta gataagtttt tttctatttt
     7621 ggcctgtttt ccatattttt ttaatatctg tatgaagcaa gctattgttg taggttgatt
     7681 ccatttttca aaacagaaaa tataatcatc gcttgacaat ggctggaaac gttcgctaag
     7741 tcgtactatt tgtctttgaa tagcttctat gacactctct gatactttga ttgtccgtat
     7801 tgaatttgta gtctttggta gcgtcttgat tttgtttact gaatcaaaat tacctgtgat
     7861 ctcaattttg ttgttttcga agtctatatt cttcagttgt aaggcagtta actcaccata
     7921 tctcatacca gttaatgtca gcacaagaac catatcagcg tacttttggt gatattctcg
     7981 acgattaagg acatcgacaa gtgcttttat ttcttgcatg gtgagaaagt tgttacgctt
     8041 tttttccagt tcttctaaag tctttggttt ttgaggaatc gtagtataat cgacctcgtt
     8101 gttttcaatg taagagtatt gaacagcgta attaaagata cctctgagcc tatgccgtac
     8161 ttttttagct gtaatatatc cgttgctttc aataattttt tcaatagcct cttgaagaaa
     8221 acgcctgtca agattagcaa gtatggtatc ggatggtatg acttccttca tcttcttatc
     8281 aactgattta caattatgtt ttgttgattc ctttactgtt tgcgcccatg atttatagaa
     8341 aaggttatag atttcttcaa atgtaatgct ttctacttgt tttgtgctga gttttttatt
     8401 tatcttctct tgtaacaaga tagcagcttg atttcttgcc tggggagttt tcttctccat
     8461 ggtcactgaa acttttttta atttctcagt atatggatct ttatatcgct caaaaaattt
     8521 gtattttccg ttgggaagtt cttccatcca cattgcgttt acctcacttt tttgataaaa
     8581 tgggtatagt aaagagggct ttttaatgcc ttttactata caggatatcc tcacactctc
     8641 cttggccaaa atttgagtgt ggggattttt taatttttca gcagcaaata cgcatcgacg
     8701 taaattaaag gtacgctttt ctctttatta ctatttgtag tgtattcgta agaaagcaag
     8761 taacgcccgt ttacagtcaa atgatctttt tctaaaaatc ttttttcgat acgtttagtc
     8821 tccatgaaca gcatatagaa atcaccgctg ggttgtgtaa caagcatttt cgtgtacttg
     8881 ccttctttaa aaatttgtac gatctccaga ttgtcgattc tcatttttaa agagaagaat
     8941 ttttctggct ctctgagaac tgttttgtaa tcgtagattt tataatcgtc tgacttgtaa
     9001 ttgtcctttg tgaccttatc aactttagtc aatagcttat caaaatattc ttctacgcta
     9061 atatcatcag atgatgatgc ctgagtggtc ggttcgctgg atgacttttg cgtttgattt
     9121 gtacaagcgg ttgaaataac aagtgcacaa agcaaaacag atgatatgga aaatattctt
     9181 ttcattttat cctactcctt tttcaattaa gtaaagccaa atattcttct tttaccatta
     9241 tttcatcggc aatggttttt aaattatact tttccataaa taccaggtaa ttaaatgtag
     9301 tggcatcttc ggctataccc aactcagctt tcataaggtg atggatcata ttcctattag
     9361 cctcaagctc acacttttcc cgaaaaagct gataagtatc tggcgcgtgg tttctatggc
     9421 ctatctcatg taaagcgact tgtacccttt tttcatcaga tatagcatca ctcaaaaaca
     9481 tagttttgag ggctgggatg taaaaggctt catctggaaa tagaccatct tcaaaaatct
     9541 ctatatctat gcctagattt tgagaaaatt ctttttcagt cataaacaat ccaacctttg
     9601 attattattg ttttctgaga tagatctcta ttatgttttg aattgctttt ttatcttctt
     9661 cagttagtgg tttaccattg aagcgcatag cagtagaggc aagttcctca acatcgactt
     9721 ctttgccttc gaaaaagaat tgttcttttt tattagcgat ggtaggatta tctgtgcgac
     9781 caagtaagta gtctgtagat acattgaagt agtcagcgat tttggatata tgttcagcag
     9841 atggagtctt tttattttta agactgtaaa tgtaattttt ccccaaacca accctatctt
     9901 ctaaagtgtt tagagaaatt ccctgttttt tagctaaact tttaattttt tcgaatgtct
     9961 caaacattga tacatcaacc tttctgaagc attacaaaaa aatattttat tttttcgcct
    10021 aaaacacttg acaaaaatta gacgaacaac taaaatagta tttgtaagta attaacaact
    10081 aaaaaaacaa ctaagaaata aattataaaa atgtttttgc gaacggtatt tatagattta
    10141 ttagtgtttt tattatgctt tcattttaga cgaacatcta aaaaaagtca agcgaaaaga
    10201 taaaaaatag ttaaattttt agttgtttct tatttacaaa ataagtaaaa aggaggaaca
    10261 catatgccag atatcacaaa tggtcgtgag aaagtcaatg attttctgaa agacaaaggt
    10321 attaaaaaaa caagtctagc gattgcttat ggctttaaac gacaggaagt aacaaacatt
    10381 ctgagtggga cgacgaaggg accacgagcg aacagtttca ttcttcaagt gattgaagat
    10441 tatgggattg agtaggaggg aataacatga atgaagttat taaagtgact gtgaatgaca
    10501 atcacgagcc gattgtatct ggtcgtcaat tgcacgaggc gttgggagtt aaaacagaat
    10561 ataagaagtg gtttagtcgc atgactgaat acggctttaa tgaaaatgag gactttttaa
    10621 aggtgaccca aaaatgtctc acctcttcaa caggtcaaaa tacgactgac cacatcatca
    10681 agctagacat ggccaaggaa attgctatga tccagcggac ggagagaggc aagcaagtcc
    10741 gacaatactt tatccaagta gaaaaagact ttaatagccc tgagaagatt atggcaagag
    10801 cattgctcat ggctgatcag aaagtccaca agctggaggc tcagattgaa gcggacaaac
    10861 ccaaagtcct ctttgcagac gcagtaagtg caagccatac atctatcttg gttggcgaac
    10921 ttgccaagct cattagccaa aacggctaca aaatcggtgc caatcgcctc ttttcttgga
    10981 tgcgcgaaaa tggctacctg attaagcgca aaggctcaga ttggaacatg ccaacccaac
    11041 gtagcatgga cttgaaactc tttgaaatca aggaaacaaa cgtgcaacac gcagatggac
    11101 atatcactgt gaacaagaca ccaaaggtca caggcaaagg acaacagtat tttatcgata
    11161 agttccttaa ttaggaatac ctgacaggtt agaaagtaga aagaatgatt gaaaataagt
    11221 gaagagaaag gagactgtat gacagacttt aaaaatttag attgtcaatt tatctttcaa
    11281 gaatgcgact gaaaattata ctgctgttag taatagtttt atcaacgatc ctgcgctgga
    11341 ttttacagcg gttggcatca tgatggtagt gctggctaat cacccaaatt ggcaagtcta
    11401 tccggatgag atagctaaaa gaaaaggtgt taaccgaaag acaatcgata agtatttcaa
    11461 aatctttgaa gaggctggat atttacgaaa aataagaaaa aaacctcctg gaaatggagg
    11521 gagtcatata ttcagattct tttcagatgt aaaaatatct gatttccaat tcgatattat
    11581 gaaacagaga ttgaacctat ctatcaaaag ggcgtctatg aattataatt ctgacattcc
    11641 aaaaagtgag atgtcagaaa gtgagatgtc agaaagtgag atgtcagatt ttgggcacta
    11701 ataaatacta actaacaaca agtattaaat aacaataaat actaactaac aacaagtact
    11761 actcttaata aataaaagag agtatacaaa aaagtatctg agaaactcag acactttcta
    11821 aaaaaatcta acttaattat agcatgaaag gggaaaaatg gaaacagttc aaatcgtgag
    11881 aattaaagat gtgatcatcg agaagatttc tgcaaacgat gaagaactag agcgcatctt
    11941 tggatgttca aaacggcaag cgggagatat gaggcgagag atgaaaaaat tgcctagtca
    12001 gcaaaaatac cttagaaacg atggtcagct tgtcacaatc aaaggttttg atgcttatct
    12061 gcaatatcga ggcagtcaat catggaagaa agaaatggct aaaaccgtta agatgacacg
    12121 atagcagaat aataactact aacaaataac aaactcatac ttatagataa taagggaatt
    12181 acagagtttt taaaggagga aagaaatatg ccaaattggg cagagggaac tcttaaatta
    12241 agaggcagac gcgaaaacgt tgcatcagct ttaaaagaaa tgctattagg agatgaaggc
    12301 gcaacgcttg aagaagaata cgatggcact ctactaagat ttaaaaacga gtatgattat
    12361 ttttatataa acggtacaag acgtgcgttt atttctagta aagatattga aatttggttg
    12421 gatgatgatt ttgtgattat cgaacttgaa gatttcgaac aagcatgggc agcattagct
    12481 gacaattaca cagaaatttc tagtaagttt gatgttgata ttaaaatttt cacttttgaa
    12541 atgggtatgg aatttacaca ggaaattgaa atttcaaaag gtgaaatcat caagaatatt
    12601 gtaaacgaaa actttactaa ctattcatgg gatgtgcctt ttagtagact tggaggatag
    12661 ataatatggc tgatttaaca tttgcagaat tacagcgaaa aatgcaaatc gaaaaacaaa
    12721 cgaaacaggg agtgaaatat ccgtttagaa ccgcagagga cataaataat aaatttaagt
    12781 ctttggatag cggttggagt gtatcatttc cagaagatga catcattcaa aaaggtgaca
    12841 aactgtatta taaagcggta gctgttgcta aaagagaaag tgatggcacg attgaaaaag
    12901 ctattggatg ggctagagaa gaagatgtac caatttttca cacacaaaaa ggggatgtga
    12961 aacagatgca agatccacaa tggacaggtg cggttggttc ttatgctaga aaatatgctt
    13021 tacaaggttt atttgccatt ggaggtgagg atgttgatga gtatccagta gaagaaagcc
    13081 aagagcaagg acagaataat cagcaacaga aaccaaacaa ccagcaagcc caaggacaaa
    13141 atcaagtaag gtatattgac aacattcagt atcaagaaat taacgacctt ataaatgata
    13201 ttgcaaaaat taaagggatg ccgttcgata cgcttgctaa ctatgtacta tctgaaaaat
    13261 taaaaggttt acaagatttt catagagtac aagttggtga ctacgaggta ttgaaaaact
    13321 atttaactga acaactagca aaagcaaaag caaagagagg taattaaaca tggtaaaaga
    13381 tgtaactaat agcttgacag aaatcaaggt ggattttcaa cctgcagtaa ttaatgttga
    13441 ccgtgaggcg atcgaggcac aagtagccgc agccattgca cagtatagcg gtcgcgaggt
    13501 tactgttgat aattacaaag aagtttatga agagcgaacc cgctttaata agctgattgg
    13561 gggcttagac actcaacgca aagattttaa ccgacaaatc aatgagccgg caaaagactt
    13621 tgataagtgg gtcaaagaaa aagtcatcaa gcctattgag ggcgtaacag atgctatgtc
    13681 agcaggactt aatgcgattg atgaacatga acgattgatg cgcgtggatg tcgtgcgtgc
    13741 tacatttgag gataagtgta tggtcgcagg gattgaaaaa tccacattcg ctgacaaata
    13801 cgatgagtac agcctcaaga aatattttaa aacaggcaag tatgagctga aaaagacaac
    13861 acttgatgaa atggatggct tagtactttc agaatttgat gccctggaag aatacaaggc
    13921 taacaagcaa gctatccaag agcaagctca agagtacgat ttgccagctg atagctatat
    13981 cagacatctt gaagatggta agagtcttgt tgatatactc aagatgatga aaactgaccg
    14041 agatgctgag attgcacgca aagagcagaa agaggctcaa gaaaaagcaa aagctgaacg
    14101 acttgaagaa attgctcaat cggccaagaa aaatgctaat gcgaatatca aggcttacga
    14161 tgccgaaaca ggcgagattt tggaacaggg tacaattaca ccagaacctc aaaacaatgc
    14221 gcgagaggtg gcaaaatttg agcctagcga gcctttggtc aaattagtac gtcttgaatt
    14281 gcacggtggt ttagaacagt gggaaaatac acaagaatat tttgaggata actttatcgg
    14341 ttttgaaact ttggaggatt aagtagaata aggagtcaga cctatgagat gtttttatgt
    14401 cagcggtaaa attgcagatc ttgatttggg gtcagaaatc aatgcagaaa attcatttat
    14461 ggccgctatt gagtttgtga aacgatatac cggcttatta aagtttggtt caaatgaaat
    14521 caaggtatca gaagtagagg aggtgcaaaa tgataaataa cgttgtttta gtagggcgac
    14581 ttacaagaga tgccgaactg agatacacgc aatctaatat tgcggttgct acgtttactc
    14641 ttgctgtaaa ccgtccattt aagaacgagg ctggagagcg tgaggctgat tttatcaatt
    14701 gcgttatctg gagacagtca gctgaaaatc ttgttaattg ggctaaaaaa ggttctctta
    14761 tcggagttac aggagtaatt caaacacgta gctatgataa ccagcaaggt caacgtgttt
    14821 atgtcacaga agttgttgcc agtaattttc aactgttgga aagtcgtaac agtcagcaaa
    14881 ataatcaagg tcatcaagac catcatggcg gttatcagca gcagggctac agtaatcaag
    14941 gcagttcttt ccaaaatgga aatagttacg ggcaacaagg cagtttcctt gaggggaaca
    15001 caacaaatct agttcctgat ttcacccgtg ataacaatcc atttggcaga cccacaaatc
    15061 cattggatat tagtgatgat gatttaccgt tttagcgaaa ggggatattc tagttaagtt
    15121 atgaaattct tagacttatt tgctggcatt ggaggtttta ggatcggcat ggaatcagcc
    15181 gggcatgaat gtataggatt ttgtgaaata gacaaattcg ctagagctag ttataaagct
    15241 atacacgata cgaaaggaga aattgaatta catgacatta caacagtatc agatgacact
    15301 attcgaggaa tcggacatgt tgatgttatc tgtggaggat ttccgtgcca ggctttcagc
    15361 attgcaggaa acagacgagg atttgaagat acaagaggaa ctctcttctt tgaaatcgca
    15421 aggttcgcat ctattctcaa acccagatat ctattccttg aaaacgtcaa gggactcctc
    15481 aaccacgaca gaggaaatac ctttgaggtc atcctctcag cgttggatga actggggtat
    15541 gatgtggaat ggcaagtgct taacagcaaa gattttggag tcccccaaaa tcgggaacgt
    15601 gtgttcatta tcggacattc tagaaaaaga ggcaccagaa gagtttttcc tatcggaaga
    15661 gcaaatagag aatttgattt tgaaccaaaa ataaagattg ttggtaacac taaaaatccg
    15721 aacgggacaa gtcaagggac tgggagcgtt gtttacgact caaacggttt agtcggtacg
    15781 ctttgcgcta gagattataa agagccaaaa caagtagcta taccagtatt gacacctgat
    15841 agagtaaata aacgacagaa tggtagacgt ttaaaaaaaa acggtgagcc tatgtttacg
    15901 ctgacggcac aagaccgtca tgggatttta attaaagaag caacaaaaaa aggttatgca
    15961 gaggctacag ttggtgatag tgtaaaccta tctcatccaa actctaaaac aaggcgaggt
    16021 agagttggta atcagatagc aaatactctc ttaactggag agagtcaagg tgtggttgag
    16081 cctgatttta ggattaggaa gctaacacct agagaatgct ggaggttaca aggttttcct
    16141 gattgggctt ttgataaggc gcaggaggtc aactctaaca gtcaattata caagcaagca
    16201 ggcaatagcg taacagtaaa cgttatttct gcaatagcac agggtttagg aggaaattaa
    16261 ccctatttaa accaatttga aaaggaaaca gaaaatgaca aaaattgaaa tcgttatggt
    16321 acttacaact ttgatgtcta tcacatgggc agcgattgtt acaattcaca ctatgcaagc
    16381 tatcaaaaag cacaaggcaa aagtggatta ttatcagaaa ccacaagtgc aatgtgagat
    16441 tgcacgtcat gtacttaaaa acaaatggta ctcagatggt ggggaggtgt ttagatgaaa
    16501 gtatttgatg gcgctatttc aaattagctt aatttaaagc aggaggacaa tatggataaa
    16561 aaacttattg ggttagatct aacccacatt gcagatggag gattacagga gaaactagac
    16621 aaagagcttg aaaaagtctt tgataacatc cttgacctaa atacagatgc gaaagcaaaa
    16681 cgaaaagtga ctatcacact tacaatgtca gcaaatgaag agcgtacagt tgttgatact
    16741 accatggagg tgaaatcaaa atttgcgcct caaaatggag tagctacaac aattcttatt
    16801 gggcgtgatt ttgatacagg gcaagtacat gctaatgagc taaaaagtac agtacctggt
    16861 caaatgtact ttgatgaaaa cggagaaatt ctgacggata ttgggcaacc agtggcagaa
    16921 attgaacaac aagcagaaac aaaaccagat attattgatt tcaacaaaaa gaaagtaggt
    16981 aactaatatg acaacagaaa atcttaaagc agcattggaa tacgcagtag aactaaatga
    17041 gcatggtttg gaaattttaa cagctgcaga tggaacagag tattatgatg ccaacaaatt
    17101 caacctcaaa gaacttgacc ctaaacgcta tcctaaaact ctggagctat caaccttgac
    17161 aagccttgtt gactatctca aaacagacct aaacaatttg aaaaaccaac gcttgattgt
    17221 agcagttgag aaaaatgatg aggtttgtgt gtggtctgaa aatgatgagt tagaacgtcg
    17281 cacattactt gttgatgtta aggcacgcat cccagagtta tcttttggcc gtttcctatc
    17341 atcggaacag ttcaatatca tgttgcaatc aaactttatt gacgataacg atcgtggcac
    17401 attgctagaa tttgctagcg cattgaaaat tgagaatggg gctgaaattg aagataatgg
    17461 agtatctcaa gtagcaacag ttaaaacagg ggtggcaagc cttgctaaag gcaaagcacc
    17521 taatccggtt acattgcgcc catatcgtac atttagcgag gttgagcaac cggcaagcct
    17581 atttgtcttt aggattgata agcaagccaa tatggcttta tttgaggcag atggtaagcg
    17641 ttgggtagct gatgcagtag gaaacattgc agcctatcta aaagagcagc tagcagacca
    17701 aaaacttatc acagtattag cataagaaag gggaaattaa aatgagtgat tacaaacaac
    17761 ggatgattga agaatacaaa caattaaaag agcgcaccaa taagttaagt ttgatgatta
    17821 gtaactatta cgtaggaaca cttgatttta aactaaaatg tcctattgag ttacttgaaa
    17881 ctcaacacta tacaatgtgt gcatatctca agatccttga acagcgtgca gaaattgaaa
    17941 acattgagtt ttaaggtaat caaaatgaaa tttgagtttt ctttgcctcg gaatactaag
    18001 ctaaaatctc taaacatggt tatcaatagt aatgacagac aacatcaaac agataaggct
    18061 aaagttacta agcgcattag agcttttgct tattggcata catcaatgaa caaggataaa
    18121 gggagggctg cttttagccc ctctaaccct tgtgaggtta cagttacaat ttacagccct
    18181 actaagtcta aattagatcc acctaacttg tatccgacag tcaaggctat cattgatggc
    18241 atgactgatg caggtatttg gacagatgat aatcataagg ttatcaaaaa gttatccttt
    18301 gtttatggtg gcttaagtga ggaaaaaggg cattatagat tagagtttga tatagaggag
    18361 gtttaaagtg attgaagtta atataaaatt cgataatttt gaagcgcatg gcttttacca
    18421 agatgatact aaactaggaa aaattagaga tgcaatcata tctcaaatga ataatgggca
    18481 tgtggttatt ttaggggaag atagaagtat tctattaaat cctaaagtta ttaaatgtgt
    18541 acaatttgag gttgtagaag atgaccagat ctaatcgttt tttgaccttt agagaatctg
    18601 agttattttg aggaggtgga gtgatggaag agttaaagaa aaaagttaat gaagtataca
    18661 actggacggt agaagacggg aaacccaaac ctcccaagca agatttacca caagcagtga
    18721 aagaccgggt ggactatttt tgggaaatgg cagaagatgg tatgacgttt atgggagcga
    18781 tggaatgcat cttcgctgat gaaaagccta ccgactatga tttgggagct actaagggtt
    18841 ggttgccaaa atctaaggag tttgatgatt ggattggcta tgcgccaagc atggctcagg
    18901 tagttattgc agtttatttg atttatggag gaaactaaga tgaatattaa agcattgatt
    18961 aagaagtatg aagaattgtg gaatgaacac agcccttttt atgaacctgt accttatact
    19021 tcaatggttg aacttttttt gaaagagttg aaacaactag acgaaccaga aaaagtcaaa
    19081 gttccgcagt ttatggcgga ttggattgat tatttcaaaa aaaatggtga ctgggatttg
    19141 tttcaagcga tggattattt gtttggaaaa aaagaaataa gggaatggct tgagtataaa
    19201 aacaaccaag acctcttcgc tcgtgcttgg cttgacggct acgaggtcga gaaagagaag
    19261 cggtatttgg tgactttaaa aaataggcag cctttggtca aatcgcaatc agggagtact
    19321 ctttatttta gtcaagatat aacagctagg aattataaag gtactcaaaa agaactagaa
    19381 gacgcaaagt tcggctgggt atttgattgc ccagggattg agattgagga ggtggagtga
    19441 tgacacaaac acttgaagaa ggaatgaaga atcaaagtaa atgcataaaa atcccaatgg
    19501 aaatcagacc gtttgatgtg ggttatcgaa tagtaaataa acacggtcaa gcgcttgctt
    19561 taaaaaacgg agcaagtata ttcgatttac catcactagc tgaaaaagct attaagaaag
    19621 agtttagtaa agatgaccca gattttgata ttgaaaaaca tttcgttgaa gaggttgcta
    19681 ttgtcaattt aagtaaattt catagttatt ttgaggaggt gatacatgac tgatgacgaa
    19741 gaaaaaaata gagcgcttgt cagttatcca tcgcagggaa atcaattggc taaagtggta
    19801 ttttttgagg gataagaaaa atccaaagag aaccattttg gagcaaaaaa ttatagtttc
    19861 tcatatcaaa actgataggc ttgaagctaa gtttttaagc aacttaaaaa aatcaactga
    19921 agattttata gataagtctg atcctaaata tttgcgggca ataaaagagg tttatgttta
    19981 cgaaaacatg aatgtcattg gagcttgtca aaaaatacta ttttatagtc cgactcaagc
    20041 ctatgtatta cttaatgcgt ggtttaacga ttattttcgt gcgacttaca cagaattact
    20101 agaaaacgcc atcttagata aataaccgta aaaaatccaa agcttatgta tctataatca
    20161 agatatataa gctttttcga aaggagagat atggagatgt tacagattga atatgtagat
    20221 ataaaatcca ttaaaccata tcacaaaaac gctaggcata atgacggaga ggcaacagag
    20281 aaagttgctg catccataaa agcttttggt tttcagcaac ctatcttagt agatgataat
    20341 aacatcatta ttacaggaca tactaggcta aaggctgctc tttctttagg tatagacaca
    20401 atacctatcg ctcacgctgt aaacctcaca gatgagcaga taaaagctta tagactagca
    20461 gataatcgag ttgctgagta ttcaacgtgg gactcagaat tattaaatat tgagctttct
    20521 caatttgaaa caatagatat ggctcagttt ggttttgagt tatcagttac agggttcaac
    20581 tttggtaacg aggaggagca gcaagaggaa actgaaaacg aggaggaaga tgctgaggat
    20641 tttcatagag ataccacaat aaaccaatac aaccttttta attatgacga tacaagggtt
    20701 gagggttttt ataacatgcc taaaatcgag ggcgtggatc atattcctaa agattttcaa
    20761 ggctttaatt atgttttaaa taaaccagat tacagctcat gcgtgcattt tttcctagat
    20821 gattatcaat ttgaaagaat atggcaaaga ccagactttt acattgaaaa gctgctagaa
    20881 tttgatagcg ccttagctcc ggattttagc ttatatcttg atatgcctat cgctatgcaa
    20941 gtatggaaca tttacaggtc aaggctgata ggtcagatta tgcaagatta cggccttaca
    21001 gttatcccta ctgtatcgtg ggctagtgag gaaagctttg atttttgttt tgacggcttg
    21061 cctaaaaact caacgctagc aatcagtaca ataggcgtaa agcaaaacaa agagcagttt
    21121 gaggtatgga aaaatggagt tactgagatg ataaaaaggt tgactccaaa aagaattgta
    21181 gtatatggcg gaaaagtgga atacgattat aaagatatag aggttgtata ttttgaaaat
    21241 gcaacaacgg aaaggatgaa agaaagtggc acaaaaacta actaaactaa aagatatttt
    21301 taaacatgtt tcaagtattg atctaggtaa agagatttta tttgaagatc ttgagcttta
    21361 caataaagaa acagaaacaa gcaaacaata ccaatctatc gaggaggcag aaaatgacct
    21421 atctttgatg gaaaaagtaa ataaaatcaa tttcactcta ggcggtggac gtggtgcaaa
    21481 ttttgagaaa gggaaagacg gtaagtatcc gggttttaga ggtgctggtg gtgcaagaga
    21541 tagtgggagc tcaaaagcct tacatccagc atctttaaac aatcaagggc gcttttcaag
    21601 tgttgaggga gctattcagg gatttattaa aaaacacggt ggctctagaa cagaatacag
    21661 tacagcagtt gactctcaag gctttgctca taattatgta cacggtggga aaaacagcgt
    21721 acaaattttg cctatctctg gtggatttac agcaatacat aaccatccga atggcagcaa
    21781 tttctcaagt acagatttac atagctttgc agcattaaaa ggtatgaata cactagttgc
    21841 aacgaatagc tctaaagcgt atcgaattac aaaaggggct aactttgatg ctaaaggctt
    21901 tgataaagct gtgagcaagt cacgttttac tacaaaagat tacaataaag gagctgacct
    21961 atggctcaag aaaaacgcta agaaatacgg gtacacttac tcatacgagt aaaagaaaag
    22021 aggctaaggt atgggtggta gaggagcaaa attaaacttg tcaacaacga aaatgacaac
    22081 tcaaaatata gagacttgat taacaaaatc gaaaagttat taggaatagc gtaaaacatc
    22141 ccctttttta acatatacaa tgaaatcata agtataaaat gcttgtgatt tttttgtttg
    22201 aaaggagggt ggaaattgcc tagagatgga actaaaaatt taaaaccagt tacagaacga
    22261 accaaagatg aagcaagagc tattagctca aaaggaggta aagcatctgg catagcaaga
    22321 agaaaaaaag ctgatctcaa aaaagcattt gaaaccctct tatctttgga tgtgacggat
    22381 agtaaaatca agaaacaact tgaggagatg ggtatggctg gcaataacga ggctttgcta
    22441 gcctttgcaa cctttcagca agctgtaaaa ggcaatcaga aagcgactga gaacataatc
    22501 aagctgacaa atactaaaga taaatacgat atacaagaac agaaagagcg tattaaagca
    22561 ctcaaatatg aaaatagaga gcgtgctgaa gctgagaaag gctcaagtga aactatcgag
    22621 atagtggatg catgggctga agatgtgagg ggggcaacgg atgaccttta atgtccagaa
    22681 gaacatcaac cctcatttca aatctgtttg gatttctagc ttaccttata atgttttgaa
    22741 aggtgggcgt aactctttta aatcatcggt tattgtactt aaactagcgt atatgatgat
    22801 aaggtatatt atcgctggag aggcggccaa tatcgttgtt atccgtaagg tggccaatac
    22861 tattagagac agtgttttca ataaagtttg gtgggcattg aacctttttg gtatagctga
    22921 gcagttcaca aaaacagtta gcccgtttaa aatcgtacac aaaacgaccg gctcaacatt
    22981 ttacttttac ggacaagatg actttcaaaa actcaaatca aacgacattg gaaatatcat
    23041 agcggtttgg tatgaagagg ctgctgaatt taatgaccaa gaggactttg accaatcaaa
    23101 cgtgacgttc atgaggcaga aacacccacg cgccaagttt gtacaattct tttggagtta
    23161 caatccacct agaaatccat atagttggat caatgaatgg tttgagagca tcaaaacgaa
    23221 taagaactat ttagctcact caagcaccta tcttgatgat gaactcggat tcgttactga
    23281 gcagatgcta gaagatatag agcgtatcaa agagaatgac tacgattatt acagatactt
    23341 atatctaggt gaggcagtgg gattaggtaa caacgtgtat aacatgagta tgtttcatgc
    23401 tattgatgct ttgcctagcg atgataagct gattggcata tcatttgcgc tagatggcgg
    23461 acatcaacag tcagcaacag cttgttgtgc ttttgggata acagctaaag gaaaagtaat
    23521 cttacttgat acctggtact actcacctgc tggccaagtg gtcaagaaag cacctagtca
    23581 gctatccaaa gagatatata cttatatacg ctcagttatt gagaagtaca gagtacaagc
    23641 cttgcaatac acaatagata gtgctgaggg agcattgaga aaccagatgt ttcttgactt
    23701 tggtttgaaa tggcatccag tcgctaaact tagaaaagtg actatgattg acagttttca
    23761 atctttgctt gctcaaggtc gcttttacta tctcaacacc gaaaacaaca agatatttat
    23821 tgaagaacac aagatgtatc gttgggatga aaagactatc aaatctgata atcctagcgt
    23881 tatcaaagaa gatgaccata catgcgacac aacacagtat tttgtgttag acaatgcaaa
    23941 attgctcggt ttgcgtgttg gtaacgttta gaggaggacg atcatgagcc tatttcaaaa
    24001 agtaaaagac ttttttagtc gagggaggta ttacatgcag acatcaaacc ttaatagtat
    24061 tttggaacat ccaaaaattg cagtgactca agaggagtat gaccggatta agagaaatct
    24121 agtctactat caatcaaaat gggatgatgt tcagtacaag aatacggatg gagatattaa
    24181 atcccgtcca atgaatcact tgccaattgc aagaacagca tcgaagaaga ttgctagctt
    24241 agtttacaat gaacaggcaa ctatcacaac aaaaaacgaa attttacaga aatttttgga
    24301 tgacatgcta actaacgacc gattcaataa gaattttgag cggtatctag aaagctgttt
    24361 ggcacttggt ggcctagcta tgcgccctta tattgatggg gataaggtca gagtggcatt
    24421 tattcaagcg cctgtgttct ttccactaga aagcaacaca caagatgttt caagtgctgc
    24481 aatccttact aagactatca aatctgaggg gcgtaagaac gtttactata cccttgttga
    24541 atttcacgaa tgggtaacag cagacggaca agaaacaggt agcacaaacg ataaaaagta
    24601 ttatcgtatt acaaatgaac tttataggtc agatgtgaat gatgtgttag gtcaacgtgt
    24661 gaacttgagt gaactagaca agtacaaaaa tttagagcct gtaacagtct ttgaaaacct
    24721 atcaagacct ctatttactt atctaaaaac tccaggtatg aataacaaag acatcaacag
    24781 ccctcttgga ttgtctatct ttgataacgc aaagacgact attgacttca tcaatcgttc
    24841 ttacgatgaa tttatgtggg aagtgaggat gggacaaaga cgagttattg tgcccgaaca
    24901 tctaacacaa agacaatatc aacgtccaga tggaacaata gattttagac cacggtttga
    24961 tgttgagcag aatgtttata tgcaaattgg cggctctagt atggatgccg ggggcattac
    25021 agaccttacc tcaccaattc gagcaaatga ttatattttg gcgatttcag agggattgaa
    25081 actctttgaa atgcagattg gtgtatcaag tggcatgttt acattcgatg gtcaaggaat
    25141 gaaaactgca acagaaattg tcagcgagaa ctcagacact tatcagatgc gaagtagtat
    25201 tgtcgcactt gttgaacaat ctatcaagga gctttgtgtt tcaatgtgtg agctcggtaa
    25261 ggcggtaggg gtttatagcg gagaaattcc agaacttgat gatatttcag ttaatttgga
    25321 tgatggtgta tttactgata ggcatgcaga acttgattat tgggctaaaa tggtagccgc
    25381 aggattctca accaaaaaac gggcaattgg taagacatta aatatttctg gtgttgaggc
    25441 agaaaaagaa ctcaatgcta tcaatagtga gttgctacct atgaatgatg ccgaacttgc
    25501 tatttatggt atgcatgacc aaaacgagga ggaagcagat gacaaaggtt aaattcggag
    25561 ttactagtgt tgactactca gcaagcattg aagatacgcc aacaataaaa ctaggtttaa
    25621 taattagagg gagcgggaga ctagatgcct cttcagttat taaaaaacta atcaaggatg
    25681 tttctgaact agaatacgaa ttagaagaat aaactggtca attggccaat tttctttcaa
    25741 gagagggctt ttgaatgaaa aaaaagagaa aacagatcac gtttaacgac caacaatttc
    25801 ctttgcaaat gcaaggcgtt ggggatattt acgaaaaatt acagattgat atctttgacc
    25861 gtatgataaa acgcttaaaa gagcgtgggt ctattgattt aatgagaaac ccttatatct
    25921 ggcagttaga gaaactaaat gatatgcaca tgctcaatga acagaatcta aagcttattt
    25981 cagagcgtac aggaattgct gaaagattgt tgcgtgatgt aattgagaat gaaggtttga
    26041 aagtctataa ggacactaaa cagcaacttg aagaagattt gaataaaata cctgagggag
    26101 agatttcaaa tggcgtaacg gacagcttag aggcttattc gaggcaagca gttagtgatt
    26161 taaaccttat caatacaaca ttacctaaga gcttgcaagt agcttataaa tcgattgtgg
    26221 aggagacagt cgcacaggta gttgcaggaa ctaaaacaag cgatgttgct ttgcatgata
    26281 ccatcatgaa atggcagaag aacgctttta cgggctttgt cgataaaggt gggaggcatt
    26341 ggaaagctga tagctatgcg agggctatta tcaagagcac aacatacaaa gtttataacg
    26401 aaatgcgtac tagacctgct gaggagttag gagtagatac tttttactat tcgatgaaag
    26461 caatggctag accagcttgt agtccgttac aagggcagat agttacaaaa ggggctggta
    26521 ggaagataga cgggataact atctattcat tattggatta tgggtatgga acagcagcag
    26581 gatgtttagg aatccattgt ggtcattatc tgacaccgtt tattgttgga gttcatgagt
    26641 taccgaactt accagactac ctgaagaatc taacaccaga acaagctgaa gaaaatgcac
    26701 gcattgaagc aggtcaaaga ggccttgaga gacttatcaa gacacataaa gagcggttgc
    26761 attacgctca taccttgcaa gatgacaaga tgatacaagc tgagcgtttg aaagttagag
    26821 ggtatcaaac taagatccgt aacttgataa atcagcatga tttcttaaca agagattaca
    26881 gacgagagaa attatatatt tcataaagga tttgtgtttc acaagtcctt ttttgtgttt
    26941 aaaaccgtaa aaaatcccta tccatcaaag gtatattgag agagtaaata atattttgct
    27001 ttaggtggga gttatccacc taaaaaagaa ctaggagggt acaaatggca tttacaactg
    27061 aagaactact caatcttggg ttgacagaag aacaggctaa gtcagtcttt gctttgcgag
    27121 gaaaagagct gaatgaggac aaatcagcct tagaaactat caaacaagag cgagatagtc
    27181 tcaaatcaca gttgcaaaaa gcagaggagc aagttgaaca cttgaaatcg cttgagaata
    27241 tcagcgctga acaaaaagat gcgattgata aattgcaagc tgaatatgac aagtataaaa
    27301 acgaagctgc agctgaactt gcacagacaa aaaaggttag tgctatcagt ctagctctga
    27361 aagatacaaa tgctttcaat ccagacaaat tgatgaaatt cattgatgtt gatgctatcc
    27421 agttagacga caacgggaaa cctcagattg atgaagtaat caacggttta aaagaaagtg
    27481 atccatatct gttcaaagct gaagaaagta agcctagccc caatatttta cctcaaggta
    27541 atccggcagg agagggtaca agtgatgttg atccgttcca agcgattatt gacgggtatg
    27601 gcaaataaca gaaaggagat tacaaatgcc aagtaatcaa aacaacgcag tgcgccgcta
    27661 tgagaaacaa tatgcgggca ttcttgagac agtttttaga gtgcgggcag cattttcaaa
    27721 cgctctagca tctattcaga ttttggatgg ggtacaagaa aactctaagg ctttctcagt
    27781 taaaacaaac aacacaccag ttgtaatcgg tgagtacaaa accggtgaaa atgatggtga
    27841 ttttggtgat aactcagggg ctcagtcacg ctttggtggt ttgacagaag ttaaatatga
    27901 aaatacagat gtcaactatg actataccct tacaatccat gaggggcttg accgttacac
    27961 agtaaacaat gatcttaacg ctgctgttgc cgaccgtttg aagttgcaat ccgaggcaca
    28021 aactcgaaca gtgaacaagc gaattggtaa atacttgtct gacaacgcta ctaatacgga
    28081 agcccttgct gattttacag atgacaaagt aaaagcttta ttcaataagt tgtcggcttt
    28141 ttacacaaac aacgaagtta cagcgccgat tactgtttac ttgcgttctg aattttacaa
    28201 cgccatcgta gatatggcat cagttacaag cgccaaaggg gcaactatct cccttgatga
    28261 aaacgggcta ccaaaatata agggctttac cttggaagaa acgccagcgc agtactttga
    28321 gacaggagtt atcgctatct tctcaccaaa cggtattgtc attccgtttg ttggtatctc
    28381 aacagcccgt gtaattgagg ctgaaaactt tgatggtgtg aaattgcaag ctgctgctaa
    28441 gggtggtact tacactcttg atgacaataa gaaagcaatt tacaaagtta caggaactat
    28501 tgtataggag gtagaacatg gcaatttaca aagcaacaaa aaatcttttc tttgagcaac
    28561 tcaacatgga tgtgattgtc aatgacatta ttgaacttga tgaagattat gctaaagaag
    28621 tcaacaagaa actaaaaaat gcttttccag atgtgaaaaa tgttttagaa cttgttgaca
    28681 aaaatggaac gcttgaacca gaagatgccc catctgtaga tgatgcatct caggcaactg
    28741 ttgaagatta aataaggggt ggcaacaccc tttattttta agggaggtta cacatgactt
    28801 atttgacaca agaggagttc gatgagttag attttgatga agttacagac tttgaaaaat
    28861 tggcaaaacg ggcaaagata gcgattgacc tatacactaa cggtatttat cagaaagaca
    28921 ttgattttga aaaagaaatt gcctatcgca aatctgctgt aaagcttgct atggcattcc
    28981 aaatagccta tctcgatgcc tctggtatta tgtcagccga tgacaaacag ctagccaata
    29041 gtgtctctat tggccgtaca tcaatctctt atagcacctc acaaagcaca ttagcaggtc
    29101 agcgatttaa tttgtctatg gatgctgaaa atgctttgag acaagccggc tttagcctag
    29161 ttgttggagt tgcctatgat cgataagcgg ttattaaaag ggattgacaa gcgtttgtta
    29221 aaggatgtgc taaccataaa aaaagtagct gataaaaacg attatgggga tgaagtatat
    29281 tcagaaccgt tgactattaa aaatgtacgt tttgatagat cagtgggggg atctggtaat
    29341 cgtaattcaa aaactggtac aggaaattca aaatcaaggc aaaaacaagg ggttatatac
    29401 ctctatccct cgctatcttt tgtgacagtt gataacagtt ggatgggtgc aaaagtaaac
    29461 gatgggatag gagattacac aattaatgga tttcaaacta actattatga tggtgagata
    29521 ttcagtcaag aaattgaggt gatctaatga atatcgccat taaagttgac ttgcagaaag
    29581 ctaaacagaa actttcgaac gaatccatga caagaggaaa gattgcagtc gctagcaaaa
    29641 tcttgctaga caatgagcaa tatatcccct tgaggggtgg agagttgaga gcttctggcc
    29701 gaatcgttgg acaaggtgat gctgttgtct atggaacagt ttatgctaga gcgcaatttt
    29761 acggagcaaa cggcattgtc acctttagga gatataccac tccaggtaca ggaaaacgat
    29821 gggatcaagt tgctactagt aaacatgctg aagaatgggc tagagctttt gtgaaaggaa
    29881 tggggctttg atgcgagaga atgactttca aaatgtactt ttaaagcata tcaagacttt
    29941 aaatttacca gttgaaccac gctttgatta ctttgaggat gacaaagatg atctggttat
    30001 caatcagata ccaggcggga aagtggatag agagtatatg gatggcacac aagaagtttc
    30061 tttgccgttt gaaatcgccg taaaggcaaa aaagaactca gtagccaatg acactatttg
    30121 gttagtcacc tcagaactag caaagataga cttagtttta ccaagtgaca ataattctta
    30181 tgaatatatg ggaatggaag tcagcaggcc tgccatgaaa ggcaaggatg agcaaggcta
    30241 ttattattac acaattgaaa ttgtggcgaa aatcgtaata gagaggaaca aacaatgaca
    30301 agacaaaaaa acgccctacg tggccatttt gtagctccat acaatggagg aactgaacca
    30361 acaacagaag atacatggtt ggaacttgct aaatggatct cagacgtatc agatgataca
    30421 gacgagaaaa cagatgatca agcatactat gacggtgatg gagttgaaga aacaaccgtg
    30481 gtcagcgtaa aaggtgctta tacctttgag ggtacttacg acccagacga taaggcacag
    30541 gctcttattg ctgggatgaa gtacaagaca ggggatgacc gtaagctatg gcacaaggtt
    30601 gtttcttctg acaagaagaa acaatgggtg ggagctgcaa ctgcaacaga aatcaaagca
    30661 ggttctggtg ctgcctctga ctatgaggtg tttggatgta agctttctta caactcaacg
    30721 ccaaaagaga ctggtattgg gtaatagctt ttgataaggg cgggcattga gccttgccct
    30781 ttttaacaac aggaaaagga gtaaagacat gacagatatt cagattgaac taaaacgtac
    30841 aggatttcca gtaaaaatcg gagaagtaga gctatggttt gatacaagtc aagagagctt
    30901 aatgcgcttt tatgacatgg aagaagaact aaaacgtcgc cttgtccaat atgaattaga
    30961 tgtggtatct gcaaatatca ataacaaaat tgagcgtgat ggagtaacta aagaagtagt
    31021 tgctggggct attgaattgg agaagaaaca gcttgagatt caatatgatc ttatttttgg
    31081 cgacggtaca tttgacaagt tatattctat atatccagat tataacgccc taaataacgc
    31141 tctagaacag accgcaatca tgttgcatga caagttggaa gaacttgctg agcaacacaa
    31201 aacggtggtg aaagagcgtg ctagtcacta tttaaacaag ggaaaagtca ctccaatcaa
    31261 gaacaacaag aaacaaaaaa agaacaaaaa gaaatagcag gtaaaaaata tgtctatgaa
    31321 attaaatgat gccttaatca caaatttttc tattgctgat aaagagtacg acatagacct
    31381 gtcttttaat aaagttctag atgtctttga aatcctaaaa gaggatgaaa tgacgcgtct
    31441 agaacaagct cagttgattg tccatttgct aactggccaa gaattatacg acatcaaaga
    31501 ggttgtagat tgttggattt acataaaaga acactttcta gggatcgaaa aagaaactgt
    31561 tcagtatgat ttgctaggca atcccatgcc aaaggcaaaa ggtgaagaag aacaagaaaa
    31621 attgattgat tttgaacaag atgcagagta catttatgct agttttttac aagcctacgg
    31681 catcaatctt ttgaaagttc aaaatgagtt gacatggaca gaatttaaag cacttttgaa
    31741 cgctttgcca gataacacaa tcatgcaaca gattatagaa atccgagcat ggaaaccaga
    31801 atatggtggg gataaaaata aaatgcgcaa attacaagct aaatatagtt taggaaagga
    31861 gggagaagat aatgtctgat ggaaaagtga ctatcgttgt cgatgtggat ggtaataaag
    31921 tcaaggttct aaacgatgag ttagataaaa cggcacagaa aggtgataga gggagcagtt
    31981 ccctaaagaa atttgcggta ggcagtgcag ttttccaact tgccgctaaa ggtgctgaac
    32041 ttttgggaga ggctttagga ggcgctattc agcgttttga cacgttagaa agttatccaa
    32101 gagtgatgca agctatgggg catagtacag aagatgtcac gcgctcaact aagaaactag
    32161 cggcaggtat tgagggtttg cctacgactt taaatgaagt ggtaggcaca gctcaacgcc
    32221 ttacctcgat tactggcgat ataaacaaat caacagattt aacacttgct cttaataatg
    32281 cctttcttgc ttctggatct tctagtgctg atgcaagccg tggtttacaa cagttcagtc
    32341 agatgttatc agctggtaag gttgacatgc aaagttggaa aacgttacag gaaaccatgc
    32401 cttatgcttt gcaaaagact gctgaatcat tcggttttgc tggccaatct gctcagaatg
    32461 atttctattc tgcattaaaa gaggggcgta tcactttcaa ccaattttca agcaaattgg
    32521 ttgaattgaa tggtggcgtt ggtggttttg cagaacttgc taaaactaac agtaaaggga
    32581 tccagacatc ttttgggaac ttaaagaatg cggttgttaa aggtgtagct aatactatca
    32641 aggctcttga cgatttaaca aaggcagcaa caggtaagac gattgctgag aacttcgatg
    32701 cattgaaagt aatcatcaat gcggcttttg gtgttattgt caacgtaatt aaagctagca
    32761 cacctgtttt tcagactttg tttagtattt tgggtactgg agcttctgta atctcatttt
    32821 tgacaccggc tattatcggt ttagttgctg ctttggtaac tatgcgtgcc atcaatcaag
    32881 cggtaaaaac gactaaggac ttgataagcg cgtggaaaac attcaaaaca acagccacag
    32941 gagcgattca gatcatcaat ctaatgacag ctgcccaagc tacttgtggc tcagtaacaa
    33001 aggctcaact ggttgctaac ttggccaata acggagcttt gacagcatcc aatttgcttt
    33061 atggggttct aactggctct atcagcttac agactgctgc tactattgct gcgactgctg
    33121 caactaccgc atttaaagca gcgctgacag ctttaaccgg cccgattggt ttggttgttg
    33181 ctgggattgg tttggttgtg ggagtatgtg tgactttgtg gcaatggcta actgccgaga
    33241 gtgaggagac caaacgcctc aaatcagaac aagaggagtt agtcaagagt acggatcaat
    33301 taacggattc tgttaaacaa agcgcaaaag aacgtcaaaa aaatcttgag tctgtaaaag
    33361 gtaatacaga atcttaccaa aaattggctg acgaaattgt ccagttatca caaaagacaa
    33421 ataagacagc agcagacaag aaaaatctta agaaaaagat tgatgctttg aacgcctcag
    33481 ttagcggttt aaatctagcc tatgataaga actctgattc tttgtctcat aacagtgacc
    33541 aaatcaaagc tcgtatatca gcgatggagg cagaatcaac atgggagaca tcccagaaga
    33601 acctgcttga tatcgaacaa aagcgtgctg aaattggcga acagctaaag aagatagctg
    33661 aacaacgcaa aaaatggaat gaagaatcca atgttagcga tagtgtccgt aaagaaagac
    33721 tgcaagaact caacgacaag gaaactgagc taaaaaatac tcagacagaa ttgcaaactg
    33781 agtacgaaaa aacgtctcaa gttcaacagg cggcatctga agcgatggct gctgctgccg
    33841 aaaatggttc aaatagacaa gttgtagcat acgaaaatat gtctaaatct caacaaaaag
    33901 caatagacga tatgcgtact aagtacaatg aattacttga gacaactacg aacatgtttg
    33961 aacaaatcaa gtataagtct gctattagtg tcgatgaaat gattgccaac ctccaaaaaa
    34021 accaagaggc ggttaataat tgggcaacaa acctcaatac attggccgaa cgtggggtaa
    34081 acgaggggat tttagctaaa ttacaagcga tggggcctca aggtgggttg tacgttcaag
    34141 aactcgttaa tgcatcagac gaaaaattgg caacattgaa cgaagtcttt actcaaggtg
    34201 gtgagtcagc tatgaatggc ttaactgctg gtatggatac gggtgctttg ggtatcacag
    34261 acaaaatcaa gggtattgta caaagtcaag tttcaagctt acaagaggaa attgcagctg
    34321 ctgacttttc tagtttggga caagaaatcc ccaacggggt cagtcaaggg atagaacaag
    34381 gagtttctac tgccggagaa tcttctaaaa acatggctaa tgatataaaa gaatccttta
    34441 cgagcgaaat ggatattaat tccccatctc gtgttttcaa tgagtatggt ggttttatca
    34501 ctactggttt agctgagggg gtagataaag gtaccaatca acctgtatca tctgttacta
    34561 atttagccaa tcaaattaag aaaccatttg atagtctgca gagtgatttc acgtacattg
    34621 gtgaaatggc gatgtctggt cttaatgcag ggctttggag tggctctggt tctgttatgg
    34681 caacagctaa ttcaattgct gaaagggtaa aagcgaccat caagagcgca ctagatattc
    34741 actcgccatc tagagcaatg cgtgatgaag tcggacgttt cattcctcaa ggtatcgctg
    34801 ttggtattga agcagatgca ggggttgttg aaaaatcaat gttgcgatta aaagaaagca
    34861 tgatgattga tactagacca gaaattgcac ttggcttaaa caagaaacta ggtgctcaag
    34921 tgactgttaa acaaagtagt aagcagacaa tagctgaaaa aatcaaagtt actatggaca
    34981 agtctagcga actactcgaa aaagccctgg atgtagctga gacggccgtt agacgaccaa
    35041 atgaaatgta cttaaacgat ggtactttag tcgccagaac aggcgataaa tttgctaaat
    35101 atcaatcgga acaactaaga cgagataata ggatgaaagg ggtattgtca tgacaaagat
    35161 aatgactttc aacggagttg atatgtctaa attctttcgt ataacagata ttatccgccc
    35221 tatcgggaac aagaggagcg tatcaactga taacgctccc ttattgggcg tgaatatcca
    35281 acaggttaag attggagaaa aagagcatat cataaaattt gacatcaaaa ccacaaatgc
    35341 aattgaaatg gaacaattaa agcatgattt ggcaggcatt ctaaacgttt tagagccagt
    35401 aaagattact tatggcgatg agccagacaa atactatatg gggttgccgg tagatgagat
    35461 tactccagaa aatttgacaa gatggttcca gcgctcagag ttaaaaataa taattcctga
    35521 tggcgtggct cacagcacga ctttaaaaaa ttttgatatc gatacaaatg aaacaagcgc
    35581 accggatagg atagtattta atttaacaaa tacaggaaca gagccagctt atccaattat
    35641 tagaattaaa cacaactcag agaatggata tattggagtt gttaacaaca gagcggcgtt
    35701 tgagttagga aatcgtgaag aggctgatac tgaaaaatac agagactctg aaacattgat
    35761 agattataga gggactaata ttctaaaagg atttcaaaat ggcactaaag gagtagctgt
    35821 aacaaatgat aataaggagc gtcttgttgg cactttgagt acaacaagta tgtgggggcg
    35881 taatcatatc gaattatcaa accgtggtac agttgaaaaa aatcgaaata atgcacaaag
    35941 tttgacatgg gctattcctg ttgatagtag tggagaagtt ggttcattga atgactatct
    36001 gctttggaga caagttttta tggcagcagt cgctaatcaa tatggtttca taaaggttac
    36061 tgtatcggat acagacggca atttcttgta tggggtggaa acttacaaac gctatcagac
    36121 acttgattgt gagtatagtt ttttcaccac tgacggcaaa ggtggataca agtttatcaa
    36181 atggtggtat tttactggga caggggctca agtaggcaaa cttgatccat ttagcgcgga
    36241 aaagggctgg tcagagttaa aaagaaacga tgatagagtt caagtgtttt ttgatggctc
    36301 tcattatgac tttattattc cggagataaa agacaaaaaa tcagcaaaaa tccatatcac
    36361 gcttggagca ctcagagact ggcctcttat atcacatatg tatgttgatg agttcatgta
    36421 tagaaaagac tttgtgacaa agagtagaga tattcctaat cgctatccaa taggttcaaa
    36481 tgttgtaatc aacagtgagg acgatagtgt gtatattgac gggatatcta aagtaagcga
    36541 agttgtagac ggttcacatt ggccagcaat tcctccagga aaatctcaac tagagttgta
    36601 tttttcacgt tttgttaaga aaaaaccaac tgtaacaatc gaatttgaag aaaggtggat
    36661 ataagatgct tttgacaatc catgatgcaa atttacaaaa ggtagcattt attgataacg
    36721 aaaaacaagg tacgttaaat tattacgatg atacttggac aagaagtctt gcaacaggtt
    36781 cgtcaacgtt tgagtttacg gtatttaaaa aggctgtaaa gtctgattta cctcttgcta
    36841 aagcctatca tcatttgaat gagcatgcat ttgtctcatt taagtacaag ggtaaaagct
    36901 ttgtgtttaa tatcattatt gttgaagaaa atgagcagac aatcaaatgt tattgtgaaa
    36961 atctcaatct tgagttaatc aatgagcttg cgaaccctta taaatctaac aaagcgatga
    37021 ctttcaaaga gtattgtgag gcgatggatc ttttaaatta tactcacctt tctattggta
    37081 tcaatgaaat atcagattat aagcgtactc tggaatggga ggggcaagaa accaaactag
    37141 cccgtctatt aagcctagcc aaacgatttg atgctgagat tgaatttgat acacagttaa
    37201 atgctgatag cactatcaaa aagtttagtg ttaatgttta tcatgaaaac gatgacaacc
    37261 atcaaggggt gggacgtgta agaaatgatg tcattgttaa atacggaaaa aacatccact
    37321 ctattacaag aaaagtggat aagactggta ttttcaatac aatcagaccg actggtaaaa
    37381 tgccaacggt tgaagaagaa ccgagcggag ataagggctc caaaagcgaa actgtaaaaa
    37441 atgcagatgg ttcaacgacg aaaaccacaa tctctacagc ctcagatggg actaagagca
    37501 aaactattgt ccacactaaa gttacaaagt tagcggacaa gacacggatc acaacgacca
    37561 caacgactcg ttctgatggt tccatagaac aaactgttac aaccagcaaa aaaggcggag
    37621 catcaacgtc tgaaacaaaa gtcttgaaaa aaccaaatcc aaaagaaaaa acaaatacaa
    37681 ctgaggatgt tttgacgatt gagggattgg atgaatggga agtaaagaac gagaaaggga
    37741 tagttgaatt ttatcaaaga gggcaagcac tgtatgcgcc tatttcaatg caactatatc
    37801 cctcaacctt tactcattca acaggggagc ttgaccagtg gacaagaaaa gattttcatt
    37861 ttgaaacaga tgagccaaac gagttaagac gtttaggtta tctcaaattg aaaaagtatt
    37921 gttatccagc tatcacttat gaagttgatg gctttgtcga tgctgatatt ggagatactg
    37981 ttaaagtcca tgatgacggt tttgcccctc tattgatgat tcaagcacgg gttactgatc
    38041 aaaaaatcag tttcacaaat ccagtgagaa ataagacaat atttgacaat ttcaaggcac
    38101 ttgaaaacaa actatcagct gatatccagt cagcctttga gagattgttt gaagctgcta
    38161 aaccatatac tatcaaattg tcaacggaca atggtgttat ctttaaaaat cagatcggcc
    38221 agagtctagt aaccccaacc ttatacaagg gaggaaaacc agtcgttgtt ggtgttactt
    38281 ggcgatgggc acttgatgga gaagtaacaa cagggatgac ttacttagtt agaggctcaa
    38341 atgtaactga tacagttact ctgacagttg cagcttacat tggaaataaa gaggttgctg
    38401 ttgatgagat atcgcttgtt aatgttgctg atggaaaact tggtacacct ggaactccag
    38461 ggcgagatgg ccgtactcct tatgtccata cagcatgggc taataatgca acaggaacag
    38521 atggatttag tcttgatagc tcaatcaata aactctatat tggtatttat acagactttg
    38581 aaccaaacga tagcacagac cctaaaaaat acaagtgggc taaagtaaaa ggagacaagg
    38641 gagaaaaagg agataaagga gaaccgggac aacgtggttt agatggcttg caaggtgcac
    38701 gaggtgaaca aggattacct ggtcgcaatg gtgcagatgg ccgtactcaa tacactcaca
    38761 tagcttacag caatagcgct gatggaacta aggatttttc tgtaagcgcc tctgatagag
    38821 cttatatcgg tatgtatgtt gattttaata gtgctgatag taatactcca tctgattaca
    38881 attggacact tgtaaaagga gctgatggcg caaacggcgt ggcaggtaag gctggtacag
    38941 atggtaggac accatactta cacatagctt acgccacatc aaataatgga tcacaaggtt
    39001 tttcaactac tgacagtaca aataaaacgt atatcggaac atacacagat tacactcagg
    39061 cagatagcac agattacaga gtgtataagt ggacgttgat aaaaggggca gatggtactg
    39121 gtatttctaa tgtaactaat tattatttag ctactacagt ctcaacaggt atcacaagaa
    39181 caagcgcagg gtggacaact acgccacagc ctatcacatc agacaagcgt tatttatgga
    39241 attatcgagt tgagctatac acaaacggta caagtaagac aacagagcct actgttattg
    39301 gtgtgcacgg
//
LOCUS       DAVLMQ010000016        35929 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000016 DAVLMQ010000000
VERSION     DAVLMQ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35929)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35929)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35929
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.016"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(135..902)
                     /locus_tag="VXF95_000975"
     CDS             complement(135..902)
                     /locus_tag="VXF95_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HEV1081544.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEVGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(899..1765)
                     /locus_tag="VXF95_000976"
     CDS             complement(899..1765)
                     /locus_tag="VXF95_000976"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HEV1081545.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNAGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(1802..3169)
                     /gene="accC"
                     /locus_tag="VXF95_000977"
     CDS             complement(1802..3169)
                     /gene="accC"
                     /locus_tag="VXF95_000977"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HEV1081546.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(3181..3603)
                     /gene="fabZ"
                     /locus_tag="VXF95_000978"
     CDS             complement(3181..3603)
                     /gene="fabZ"
                     /locus_tag="VXF95_000978"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HEV1081547.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGTLTFAIGN"
     gene            complement(3600..4085)
                     /locus_tag="VXF95_000979"
     CDS             complement(3600..4085)
                     /locus_tag="VXF95_000979"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HEV1081548.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPSPVAPTSAPAETVAEEVPAPAEASVATEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(4088..5323)
                     /gene="fabF"
                     /locus_tag="VXF95_000980"
     CDS             complement(4088..5323)
                     /gene="fabF"
                     /locus_tag="VXF95_000980"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HEV1081549.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFIKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEYAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAVKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(5345..6076)
                     /gene="fabG"
                     /locus_tag="VXF95_000981"
     CDS             complement(5345..6076)
                     /gene="fabG"
                     /locus_tag="VXF95_000981"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HEV1081550.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(6110..7030)
                     /gene="fabD"
                     /locus_tag="VXF95_000982"
     CDS             complement(6110..7030)
                     /gene="fabD"
                     /locus_tag="VXF95_000982"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HEV1081551.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPVVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEATVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(7023..7997)
                     /gene="fabK"
                     /locus_tag="VXF95_000983"
     CDS             complement(7023..7997)
                     /gene="fabK"
                     /locus_tag="VXF95_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HEV1081552.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(8116..8340)
                     /locus_tag="VXF95_000984"
     CDS             complement(8116..8340)
                     /locus_tag="VXF95_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1081553.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(8400..9374)
                     /locus_tag="VXF95_000985"
     CDS             complement(8400..9374)
                     /locus_tag="VXF95_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HEV1081554.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLISLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(9374..9808)
                     /locus_tag="VXF95_000986"
     CDS             complement(9374..9808)
                     /locus_tag="VXF95_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HEV1081555.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(9902..10687)
                     /locus_tag="VXF95_000987"
     CDS             complement(9902..10687)
                     /locus_tag="VXF95_000987"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HEV1081556.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            11012..12376
                     /locus_tag="VXF95_000988"
     CDS             11012..12376
                     /locus_tag="VXF95_000988"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HEV1081557.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            12379..12750
                     /locus_tag="VXF95_000989"
     CDS             12379..12750
                     /locus_tag="VXF95_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HEV1081558.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGRKISRHFEVFTDKGKFLFASKDSGAILKIARKKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            12964..14238
                     /gene="serS"
                     /locus_tag="VXF95_000990"
     CDS             12964..14238
                     /gene="serS"
                     /locus_tag="VXF95_000990"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HEV1081559.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLTNYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSATKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(14263..15162)
                     /locus_tag="VXF95_000991"
     CDS             complement(14263..15162)
                     /locus_tag="VXF95_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HEV1081560.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDMLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACPERRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPTWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(15272..15820)
                     /locus_tag="VXF95_000992"
     CDS             complement(15272..15820)
                     /locus_tag="VXF95_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HEV1081561.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(16038..17360)
                     /locus_tag="VXF95_000993"
     CDS             complement(16038..17360)
                     /locus_tag="VXF95_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HEV1081562.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSPVVIAETKKYFDK"
     regulatory      complement(17451..17539)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(17703..20039)
                     /locus_tag="VXF95_000994"
     CDS             complement(17703..20039)
                     /locus_tag="VXF95_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HEV1081563.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(20143..20691)
                     /locus_tag="VXF95_000995"
     CDS             complement(20143..20691)
                     /locus_tag="VXF95_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HEV1081564.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPITTSWLKQIWVTNLIG"
     gene            complement(20688..20990)
                     /gene="zapA"
                     /locus_tag="VXF95_000996"
     CDS             complement(20688..20990)
                     /gene="zapA"
                     /locus_tag="VXF95_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HEV1081565.1"
                     /translation="MANLNRFKFTFGKKTLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDAKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            21077..21958
                     /locus_tag="VXF95_000997"
     CDS             21077..21958
                     /locus_tag="VXF95_000997"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HEV1081566.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNPISLEEKAEG
                     KYLSVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKKRLER"
     gene            21962..22576
                     /gene="lepB"
                     /locus_tag="VXF95_000998"
     CDS             21962..22576
                     /gene="lepB"
                     /locus_tag="VXF95_000998"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HEV1081567.1"
                     /translation="MNSFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRFWPITRIGTF"
     gene            22656..22778
                     /locus_tag="VXF95_000999"
     CDS             22656..22778
                     /locus_tag="VXF95_000999"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="HEV1081568.1"
                     /translation="MKIKEQTRKLAVGCLKQCFEVVDRTDEVSSKYCFEVADGS"
     gene            22855..25221
                     /locus_tag="VXF95_001000"
     CDS             22855..25221
                     /locus_tag="VXF95_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HEV1081569.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYIFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGLSAKNREAFVSTLRLNYGTEMVLAKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLVRILEKGKQKSHDLETIQKHITTIEEELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDFRKKNNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSEESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILDAALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKGDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDSIPAMIGITDTDLKEIFGK"
     gene            complement(25269..26552)
                     /locus_tag="VXF95_001001"
     CDS             complement(25269..26552)
                     /locus_tag="VXF95_001001"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HEV1081570.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVITAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAQFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(26746..27105)
                     /locus_tag="VXF95_001002"
     CDS             complement(26746..27105)
                     /locus_tag="VXF95_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1081571.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNRFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPIIAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNIT"
     gene            complement(27404..28318)
                     /locus_tag="VXF95_001003"
     CDS             complement(27404..28318)
                     /locus_tag="VXF95_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HEV1081572.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LQDSPGTNNFSLPNVSPTYGQYYTNQSEVIIGKNDLVKVKNTLQYPYSTSAYVESEFR
                     GVKNGKDVTYRGSANFIKDNVLITAAHNIYKHEFGKDAEELYVTPARTPNSVPFGRIK
                     VKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLGTLGLPTSQKNLTGITVTITGY
                     PSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSGSTVYDASNRVVGVHTLGDGAN
                     QINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(28468..28563)
                     /locus_tag="VXF95_001004"
                     /pseudo
     CDS             complement(28468..28563)
                     /locus_tag="VXF95_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411442.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(28640..28951)
                     /locus_tag="VXF95_001005"
     CDS             complement(28640..28951)
                     /locus_tag="VXF95_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002877158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1081573.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(28876..29118)
                     /locus_tag="VXF95_001006"
     CDS             complement(28876..29118)
                     /locus_tag="VXF95_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HEV1081574.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(29119..29751)
                     /locus_tag="VXF95_001007"
     CDS             complement(29119..29751)
                     /locus_tag="VXF95_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081575.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(29765..30760)
                     /locus_tag="VXF95_001008"
     CDS             complement(29765..30760)
                     /locus_tag="VXF95_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1081576.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQTQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKFPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERIEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(30757..31455)
                     /locus_tag="VXF95_001009"
     CDS             complement(30757..31455)
                     /locus_tag="VXF95_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HEV1081577.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(31532..32542)
                     /locus_tag="VXF95_001010"
     CDS             complement(31532..32542)
                     /locus_tag="VXF95_001010"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HEV1081578.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(32526..33533)
                     /locus_tag="VXF95_001011"
     CDS             complement(32526..33533)
                     /locus_tag="VXF95_001011"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HEV1081579.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTKTLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(33520..34473)
                     /gene="mvaD"
                     /locus_tag="VXF95_001012"
     CDS             complement(33520..34473)
                     /gene="mvaD"
                     /locus_tag="VXF95_001012"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HEV1081580.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(34455..35333)
                     /gene="mvk"
                     /locus_tag="VXF95_001013"
     CDS             complement(34455..35333)
                     /gene="mvk"
                     /locus_tag="VXF95_001013"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HEV1081581.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(35455..35784)
                     /locus_tag="VXF95_001014"
     CDS             complement(35455..35784)
                     /locus_tag="VXF95_001014"
                     /inference="COORDINATES: protein motif:HMM:NF024736.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1081582.1"
                     /translation="MTRKAYDTDLNDQEWAKIEPYFCKHRTYKWPKRVLVNETLYVTK
                     TGCQWRMLPHDFPLYLMVWSFFHRSMTTGWFQVNGRWYYAYSSGALAVNTTVDGYSVN
                     YNGEWVR"
BASE COUNT        10436 a         8294 c         6831 g        10368 t
ORIGIN      
        1 tttttgtaag cttacatcta cagtatacat cttttttgtc tattttatag cccatctcct
       61 caactgtcaa tttttcaacc tgaattgcat ttttccataa aaaatgagac ctttctagtc
      121 tcatttagtc attcttagta ttttctaaat cgttgatagc gttcttccag caactcttct
      181 agcggttttt gtgaaagtct agccagctcc gtttggagtt cttttttgac actcttaatc
      241 agttctttac tagaaagtcc tacttcagaa atcaccttat ccaccacgtc catttctaac
      301 agttcatgcg aagtgatttt catcagttct gctgcttcca tggcgcgagt accgtccttc
      361 cataaaatgg aagcaaagcc ttctggactg agaatggcat agatagaatt ttccagcatc
      421 cagacacggt ccgcgacagc tagagccaga gccccgcctg aaccaccttc accgataata
      481 atggcgataa taggaacttt caggtcactc atttccatga gattgcgagc gatagcttcc
      541 ccttgaccac gttcttccgc tccgacacca ggataagcac ctgctgtgtt gataaaggtc
      601 acaactggac ggccaaattt ctcagcctgt ttcatcaacc gcagtgcctt tcggtagcct
      661 tctggatgtg gttggccaaa attccgtttg aggttgtctt gcaaactctt gcctttttgg
      721 ataccaacca ctgttacagc ttggtctcca agccaaccaa taccaccaac aactgcacca
      781 tcatcacgaa aagaacggtc accatgtaat tggataaatt catcaaaaat gcctgtcgca
      841 aagtccaagg ttgtcaagcg actctgctca cgcgcttctc tgactatttt tgcaatattc
      901 atctaggact ccctccatgc aatctgacta ggctagcaat cgtatctggt aagtctcttc
      961 ttttgacaat agcatccaca aagccatgtt ctaataggaa ttctgccttt tggaaatcct
     1021 caggcaagct ttcacgaacc gtattttcaa tcacacgacg cccagcaaaa ccaaccaagc
     1081 tctgtggttc agccagaatg atatcgcctt ccatagcgaa agatgctgtc acaccaccag
     1141 tcgttggatc tgtcaaaatg gtcaggtaaa agagaccagc atttgaatgg cgtttaaccg
     1201 ccgcagagat cttagccatc tgcatgagac tcatgattcc ttcctgcata cgggctccac
     1261 cagaggctgt gaataggaca actggcaatt tttcgacagt cgcatactca aacaaacgag
     1321 tgattttttc acctacaacc gtacccatag aagccatgat aaagttagaa tccataatcc
     1381 caagagccac agtctgacct ttaataagag cagttcctgt cacaacggct tcatgcagac
     1441 ctgttttttc acgcatagat gccagtttct tttggtaacc agggaaatgc aagggatcct
     1501 tgctttcaat ccctgtaaac aattctttga aggttcccat atcaatcgtc aaagccaagc
     1561 gttcttgggc agaaatacga aaggtatagc tacagtgcgg acagatacgt tcacttccca
     1621 gatccttctg atagatggta tgcttacagc ctggacactg ggaaaataat tcatctggaa
     1681 cctctggctt agcttgaggt ttttccctaa ccgaacgatt gggattgatt cgaatatact
     1741 tatctttttt actaaataga gccattgatt ccccttttcg gtttaaactc ttaaagtcat
     1801 tttattcttt ttcttgatat ttaggtaaga aggtttccat caagaaggaa gtatcataat
     1861 ccccagcaat gacattgcga tctgaaatga ggtcaagctg gaaatctgca ttagtctgca
     1921 ctccttcaat ctctaattca tagagggcac gttgcatttt catcaaggcg tcaaaacgat
     1981 tttcgccgtg tactatgatt ttggcaatca tactatcata ataaggcgga atggtataac
     2041 ctggataaac tgctgaatcc acgcgcaagc caactccacc acttggcaga tagagattag
     2101 taatcttacc tggacttgga gcaaagttaa aggctgggtt ttctgcattg atacgacact
     2161 cgatggcatg accacgtagg acaatatctt cttgcttaac agacaaaggc tgacctgccg
     2221 caatgcaaat ctgttcctta acgatatcaa cacctgaaac aaactctgtt actggatgtt
     2281 ctacctgaac acgagtattc atctccatga aatagaaatt gctacttgct tcatcaagaa
     2341 gaaattcaat ggttcctgca ttctcatagc caacaaactc tgccgctcga acagcagcag
     2401 cacctatttc atgacgcagc gtttttccga ttgcaatcga gggactttct tccaaaacct
     2461 tttggttatt cctttgaaga gaacaatccc gttcacccaa gtgaatcaca tgtccatgct
     2521 catcacctag gatttgaacc tcaatgtgcc gagctggata gataacccgt tctatgtaca
     2581 tggcaccatt gccataattg gccttggcct cactagaggc agtttcaaag gcagaaacga
     2641 ggtcatctgg tttttcaacc ttacgaatcc ctttaccacc tccacctgct gaagccttga
     2701 gcataacagg atagccaatt ttttcagcaa caatcaaagc ttcttcagag ttatgcactt
     2761 ctccatctga acctggtata acaggcacac ctgctttaat catctgagca cgcgcattga
     2821 tcttatcccc catcatatcc ataacatgac cagatggacc gataaacttg atacctactt
     2881 cttcacacat ggtcgcaaat ttggaatttt cactgagaaa tccaaaacca gggtgaatag
     2941 cttctgcctc agtcaagact gcagctgata gaactgcatt aatattgaga taagactctg
     3001 ttgccttgcc aggaccaata caaactgctt catctgccaa aagcgtatga agagcttcct
     3061 tatcagcagt tgaataaacc gctaccgtcg caatccccaa ttcacgtgcc gcacggataa
     3121 tacgaaccgc aatttcacca cgattggcaa ttaaaatttt tcgaaacatg gagaacctcc
     3181 ttagttccca attgcaaaag taagggtacc actggctgca agcttgccat ccacttcagc
     3241 ctttgcttca accacagcta tggtgccacg acgttttaca aaagtcgctg tcataaccaa
     3301 ttggtcgcct ggtacaactt gcttcttaaa cttaaccttg tccataccag cgtaaaagac
     3361 cagttttcct ttattttcag gttttgataa ctccaacaca ccggcagttt gcgccaaggc
     3421 ttccataatc agaacacctg gcataactgg gtattgagga aagtggccgt taaagaaagg
     3481 ctcgttgatg gtcacatttt tgatagcaac aatggtatcc tcgctcactt ccaagacacg
     3541 gtccactaga agcataggat aacggtgggg aagggcttct ttgattcctt gaatatcgat
     3601 catttgatac gtaccaatcc tttaccaaac tcaaccattt cttcgttaga gacgagaatt
     3661 tccgttacca caccatcctt aggagctggg atttcattca tgactttcat ggcttcgata
     3721 attaccaatg tttgaccttt tttgacacta tcaccaactg taacgaaggc aggtttatct
     3781 ggtccagcag ccaagtaaac cactccaaca agtggactct ctacaagatt tccctcagta
     3841 gccacacttg cttcagctgg agctggaact tcttctgcta cagtctctgc tggagcagat
     3901 gtaggagcta ctggactcgg tgttgctaga acgggtgctg gagcgacttg agttgcaact
     3961 tcaggcacag gtctcgcttc attcttgcta aactgcaact catccgtccc atttttataa
     4021 gaaaattctc tcaaacttga ctggtcaaat tgagtcatca agtctttaat atcgtttaaa
     4081 ttcatactta tctattctcc caacgtttga aagcaagaac tgcattgtgg cctccaaaac
     4141 caaaagtatt tgaaatagcg tatggaattt ctttctccaa gccttgtcca taaacgacat
     4201 tagcttcgat ataatctgat acttcacttg tcccagctgt cattggtaca aagttatgac
     4261 gcatagcttc gatggtgacg atagcttcta ctgcacccgc agcccccagc aaatgtcctg
     4321 taaaagactt ggttgatgat acaggtactt ccttaccaag aacagctacg atagctccac
     4381 tttctccttt ttcattggca ggagttgacg ttccgtgagc attgacatag gctacttgct
     4441 ctggagaaat ctcagcttct tccaaggcta gtttgatggc cttgacagct ccctgacctt
     4501 ctggatgtgg agaagtcatg tggtaggcat cacaagtatt tccgtaacca accacttcag
     4561 ccaggatagt agctccacgt ttttcagcgt attcaaggct ttctagaacc aacatccctg
     4621 aaccttcacc cataacaaac ccattgcgat ccttatcaaa tgggatcgaa gcacgagttg
     4681 gatcctctgt agtagagaga gctgttaagg cttggaaacc agcgatggca aaaggtgtga
     4741 tagaagcttc tgttcctccc accaacatca catcttggaa accaaactta atggagcgga
     4801 aggcatcccc aatcgcatca tttgatgaag agcaggcagt attgatagat ttacaaacac
     4861 cgtttgcacc aaaacgcatg gctacattcc cagaagccat atttggtaaa gcttttggaa
     4921 gagtcattgg tttgacacgt ttgggtcctt tttcatgaag gcgaagtacc tgatcttcaa
     4981 tttccttgat tccaccaata ccagatgcaa cgataacacc aaaacgatcc ctattaagag
     5041 cctctacatc aagattggca tgatttacag cctcttgggc tgcatacaag gcatataaag
     5101 aatagttatc aaaacggttg gtatcttttt ttataaagta tttatcgaac ggaaaatctt
     5161 ggatttctgc cgcattatgc acatcaaagt cactatgatc aaattttgta atgccaccaa
     5221 tgccgatttt cccagttgct aaactattcc aaaattcttc tggtgtattt ccaattggag
     5281 atgttactcc ataacctgtt accactactc gatttagttt cattcttttc acctctagct
     5341 ttcgctacat acttaagcca ccatcaatgg caaccacttg accagttaga taatcttggc
     5401 ctgctaaaaa tactgtcaaa tctgcaacct gctctgcctg cccaaattct ttcatcggaa
     5461 tctgagctag tgtagcttcc ttaatcttat ctgataagat agctgtcata tcagactcaa
     5521 tcattcctgg agcaatcaca ttgactcgta tattccgact agcgacctcg cgtgccacag
     5581 acttggtaaa gccaatcaag ccagccttag aagcagcata gttagcttga ccaatattcc
     5641 ccatcaaacc aacaacacta gacatattaa tgatagcacc ttctctggct ttcatcatcg
     5701 gtttcaagac tgattgtgtc atattaaagg caccagtcag attgaccttg agcacttttt
     5761 caaaatctgc ttctgtcatc ttgagcataa gagtatcttg ggtaatccct gcattgttga
     5821 ccaaaacatc tactgaaccc agttctgcaa tagcttgatc aatcatacgc ttagcgtctg
     5881 caaaatctga tacatctcct gaaatgggaa ccaccttgat accatagttt gaaaactcag
     5941 cgagcaattc ttctgagatt gccccacgac tgtttaagac aatgttggct cctgcttgag
     6001 caaacttgtg ggcgatggca agaccaattc cacgactcga acctgtaata aagatatttt
     6061 tatgttctag tttcattttt ttcctttcaa aacttctact tattttagtc tatttttcta
     6121 aaagtgctac taaactcgct tgatcttcca catgagctaa gtgagcagtt tgatcaattt
     6181 ttttaacaaa acctgacaag actttccccg gtccaatctc gataaagttg cttatgcctg
     6241 cttcttgcat gaccccaata ctttcataga aacgaacggg ttccttgacc tgacgcgtca
     6301 agagctgagc aatgtcctct ttttgcatca cagtagcttc tgtattgccg actaggggac
     6361 aagtaaaatc tgaaaaactt acctgagcta gagtttcagc tagtttctgg ctagcaggtt
     6421 caaggagagc ggtgtgaaag ggacctgaca ccttaagagg aatcaagcgt ttggcacctg
     6481 cttcttgcaa aagttcaacc gctcgatcaa ctgcaaccac ttctccagca atgacgattt
     6541 gtgcaggtgt gttatagttg gctggagtaa ccactccaag ttcagaagct ttttgacagg
     6601 cttcttcaat gacctctact ggcgtattga gaactgctac catcttgcca gagtcagcag
     6661 gagccgcttc ttccatatag gctccacgct tagctaccaa ggcaaccgca tcttcaaaat
     6721 ccaaggcgcc gcttgccacc aaggcagagt attctccaag agacaaacca gcaaccatat
     6781 caggctgata gcccttttct tgcaataaac ggtagatagc aaccgaagtc gctagaatgg
     6841 ctggttgcgt atagcgggtc tgattgagtt tgtcttcttc cgtatcgatg agataacgta
     6901 aatcataacc gagcacctga ctcgctcgat caatcgtttc tttgacaacc ggatactgat
     6961 catagaaatc ccgtcccatc cctagatact gggcaccttg accagcaaat aaaaaggctg
     7021 ttttagtcat ttcttacaac tcctgcccag cgagaggctt cttcttgaat tttcttagcg
     7081 gctccgtaat acaaatcttt taggatttct tcagctgttt cttctttaga aacaagccct
     7141 gcgatttgac ctgccatgac agagccacca tccacatcac cgtgaacaac tgctttggct
     7201 agggcacctg ctcccatttg ttcaaagatt tctaaatcag gatcttcctg cttaaaggca
     7261 tctttttcag ccagttcaaa atctctagtc aactgatttt taatagcacg aacagcatga
     7321 ccaaagtgct gagctgaaat cgtagtatca atatcccttg cttttaaaat tttctccttg
     7381 tagtttggat gagcattcga ctcttttgca actacaaacc gtgtccccac ctgtacagcc
     7441 tctgcaccta gcataaagcc agccgcagca ccttcaccat ccgcaattcc tcctgcagca
     7501 ataacaggaa tagatatagc tgtggctacc tgtcgcacca aggtcatggt tgttaattta
     7561 ccgatatgcc ccccagcttc cattccttcc gcaataacag cgtctgcacc gattttttcc
     7621 atgcgtttag ctaaagcgac actaggaaca acaggaataa cgattatccc agcttcatgg
     7681 aaacgttcca tatacttgct tggatttcct gctcctgttg tgacaacttt aacaccttct
     7741 tcaataacga gatccacgat gtcttccaca aagggagata agagcatgat gttgacccca
     7801 aagggtttat cagtcaatga tttgatttta tcaatattgg ccttgacaac ttctttcggg
     7861 gcatttcccc caccgataat tcctaatcct ccagccttgg aaacagcccc tgccaaatca
     7921 ccatcagcaa cccaggccat ccctccttgg aaaataggat agtcaatctt caataattct
     7981 gtaatacgcg ttttcatagt gcctccaacc ttccttgctt acgtaatagt tcgatttcac
     8041 cataatttga cagtcaaact attacctaaa caagagggag tgggtttctc cctactcctt
     8101 ctactaatat tctgcttatt ttgcttgctc ttcaacgtaa gcaaccaagt caccaactgt
     8161 tttcaagtca ttttctgctt cgatttggat atcaaaagca tcttcgattt ctgagattac
     8221 ttggaacaag tccaatgaat ctgcgtccaa atcatcaaaa gttgattcaa gtgttacttc
     8281 tgatgcgtct tttccaagtt cttcaacgat aatttcttgt actttttcaa atactgccat
     8341 gataggactc ctttaaaata aatagttttt ttataacaat gtgttcacca catgattacc
     8401 taaattgtaa gaatgagcgt gccccaggtc aagcctccac cgaagcctga tagaagaaca
     8461 gtctggctac catctaaaga gatgagacct tgttctacac actctgaaag taaaatcggg
     8521 atactggctg cactggtatt gccatattcc atcatattgg ctggaagttt ggctcggtca
     8581 acaccaattt ttctagccat cttatccaaa atacggtcat tggcttgatg aagtagcaga
     8641 taatccaagt ctgtcacctc tataggagat tcatcaatag tctgcttgat agacttggct
     8701 acatctcgaa tggcaaaatc aaagactgtg cgtccatcca tcttcaaaaa cgaatctgca
     8761 ctttcttgat ctgaaaatgg agaatgcaaa cctgaatgcc cataagttaa acactcgctg
     8821 cgacttccat cgctattgag actctcagct aagaaatgct cttgctcgct agcttctaac
     8881 aagacaccac cagcaccatc tccaaacaac acagctgttg atcgatccga ccaatcgact
     8941 gccttagaga gggtttcact accaatcacc aagccttttt gaaagcgacc agaagcgata
     9001 aacttttcag cagttgaaag agcaaataca aatccactgc aagccgcggt taagtcaaaa
     9061 gcaaaggctt tattagcgcc aatattagct tgaacacgag cagctgtaga gggcatcatc
     9121 gaatctggag taatggtagc taggatgata aaatccagtt cttttcctgt tattccagct
     9181 tttgccatca gtttcttagc aacctctgta gccaaatcac tggtagattc tgttcttgaa
     9241 atatgccttt gtcgtattcc cgttcgactt gaaatccact catcattggt atccataatc
     9301 tgagccaagt cgtgatttgt aaccacttgc tctggcacat aatgagcaac ctgacttatt
     9361 tttgcaaaag ccattatttc aaatcctcca aaaattggta aagattagtc aagcctttac
     9421 ccatgacagc aatttcttcc tcgctcatgc catcaataat tttttctacc atggccttgt
     9481 ggaagcgttt atgcagtcta tgaatcaagc gacccttctt tgtcaaatgc agatgcacca
     9541 cacgacgatc ctgttctgac cgaactcgct caatgtagcc cttacgctct aaattgttca
     9601 aacttgtcgt aacagttcca agagttacca tcaactcttt tgacacttga cttggagtca
     9661 catctggagc cttaccgatg acatcaatcg tatgcatttc tttgatggag atatccttaa
     9721 aacgactacc tctcaagttc acttcctcaa ttacaaggac attgttaaat atagatgtta
     9781 aatattcatt gattcgttgg tagtccattt ttcatatccc tccttcttca aaaaactttt
     9841 acaatcaaaa catttgacag aaagaattat atcaaaattc aaagaatgat gcaagtattt
     9901 tttattttcc tgtaaattta ggtcttcttc tctccgaatg agctcgcact ccttctttga
     9961 aatcctctgt ttgagctaag gatttctgta ggttcagttc taaagtagcg taaccctgcc
    10021 agtctttaaa ctggctctcc caaaccaact tcttaatggc agcataggaa ttacttgaag
    10081 cacgtcttaa ttttttaaga agctgttctc tcgtcttttc aagtttttca gcttcagaaa
    10141 cgcggtaaac caacccccat tctagggctt tttctgccgt taaagcctct cctgtcatag
    10201 ctaattgagc agcacgcgtc acaccgatac tgcggctcaa gagatgaatt ccccctgcat
    10261 ctggagccaa accaacacca acaaaggctt ggataaactt agccttatcc gtcgccaaac
    10321 agaaatctgc cgcaacagcc atattcgctg cggcacctgc aacagcaccg tcaacttcca
    10381 ttaaaacagg tttggctatt tgcttgattt tataagaaat cgtattgacc aactctgcga
    10441 tttttgtcaa tgatggaata tcatcctcat ccactgcccg cttcatctct accaaatctc
    10501 ccccaactga gaagaccttt ccattggcat tgattaagat aaaatgcaca gctggatttt
    10561 cttctgccaa agtcagagct tctaaaatct cctcacacat gggaatatga aaaccatttg
    10621 cgacctcagg acggttcaag gtaaggattg ccaagtcctc ttcaagctga taaataatgt
    10681 gttccatcag ggctcctttt tattttataa gcagtttata ctcttcgaaa atctctttaa
    10741 accgcgtcag cttccatctg caacctcaaa acagtatttt gagctgactt cggctagctt
    10801 cctagtttgc tctttgattt tcattgagtg ttaaattatt tcactgtcaa agtatatctt
    10861 ttttaggagc agaaagcaag aaaaaatcga ctgaaagtgt ctcagccgat aagaaaggct
    10921 cgctttaggc tagaaagcat cttattttct tcattgaaaa aagcctttct ttctgctata
    10981 atcgtataaa atacttactt taggagttct tatgaaagtt gttaaatttg gaggtagttc
    11041 tcttgcctct gctagtcaat tagaaaaagt tttaaacatc gtcaaaagcg attcagagcg
    11101 tcgttttgta gtcgtttctg cgcctggtaa acgcaatgct gaagatacta aggttacgga
    11161 tgccctgatt aaatactacc gcgactatgt tgcgggtaac gatattagca agagccaaag
    11221 ctggattatc gaccgctatg ctgctatggt tagtgaattg ggactaaaac cagctgtgct
    11281 agaaaaaatt tctaaaagca ttcacgcctt ggccactctt cctattgaag aaaatgaatt
    11341 tctctacgat actttcctag cagccggtga aaataacaat gccaaattga ttgctgccta
    11401 ctttaaccaa aatggtatcg atgcacgcta tatgcaccct agagaagctg ggattgtggt
    11461 cacaagtgaa cctggtcacg ctcgcatcat tccatcaagt tatgacaaga ttgaagaatt
    11521 gacaaacacc aatgaagtcc ttgtcattcc tggtttcttt ggtgtcacta aggaaaatca
    11581 aatctgtact ttctcacgtg gaggttctga tattacaggt tctatcattg ctgctggtgt
    11641 caaagctgac ctctatgaaa actttacgga cgttgatggt atctttgcag cccaccctgg
    11701 tattatccac caaccacact cgattcctga gttgacctac cgtgaaatgc gcgagttggc
    11761 ctatgcaggc ttctcagtcc ttcatgacga ggctcttctt cctgcctacc gtggaaaaat
    11821 tcctctggtt atcaagaata ccaacaaccc tgaccatcca ggtactcgta tcgttctaaa
    11881 acacagtaat gatgaatttc cagttgtggg aattgctggt gactcaggct ttgtcagcat
    11941 taacatgtcg aaatacctca tgaaccgtga ggttggattt ggccgcaagg ttctgcaaat
    12001 cctggaagaa cttaacatcg gttgggaaca tatgccaaca ggtatcgacg atctttctat
    12061 cattctccgt tctcgccaac taactcccat caaggaagaa gaaatcctgc gtcagttggt
    12121 tcaaaaggct aaagtagatc atgcagaaat cgaacacgac ctttctatca ttatgattgt
    12181 tggtgaaaaa atgaagagcc atatcggagt gactgctact gcgacacgcg ctctatctga
    12241 aaacaaaatc aacatccaga tgatgtctca aggttctagt gaagtttcta ttatgtttgt
    12301 tgtcaataaa gaccaagaga aagcagcaat taaagccctc tacaatgcct tttttggaga
    12361 aagtaaggaa gactaagcat ggctcaatca cttaacaaaa cagtactcct cagtacgaca
    12421 ggcacttcct acctctctat cgctgggaaa gttgggaaat tccttgtcgg agatcaggct
    12481 ttggaatttt acccagatgt caatgtcgaa caatttatcc agattccttg gagccatatc
    12541 aatcagattg gagccaatgt cactggacgc aaaatcagcc gccacttcga agtctttaca
    12601 gacaaaggaa aattcctctt tgcttcaaaa gactcaggtg ccattctcaa aattgcacgc
    12661 aaaaaactag gcaatgacaa ggtcgtcaaa cttccgaccc tgattcagac aattagccaa
    12721 aaatttaaaa atctatttgc aaaaaagtag aaactttagt ataatcatag caacggataa
    12781 gtaggttatc ttcttctttc agaaagtctg cgggtactgc gagcagatag gagggatagg
    12841 tgaaattcta ccgttagtaa caattacata cacaatcaag tgcacacctg tgaagttgga
    12901 tggaaccgtg gccctgccac tccaacgttt tgtcaggcgt gcttttttca taaaggagtt
    12961 cttatgttag atatcaaacg tattcgtaca gattttgaag ctgtcgcaga aaaattagct
    13021 acacgtggtg tagatgctgc tgtcttgaat gaaatgaaag aaatcgatgc taaacgtcgt
    13081 aacatcttgg tcaaggttga aactctcaaa gcagaacgta acacagtttc tgctgagatt
    13141 gcccaagcta agcgcaacaa ggaaaataca gatgacaaga ttgctgccat gcaaaatcta
    13201 tctgctgagg ttaaagcctt ggatgctgaa ttggcagaaa tcgatgctaa attgacagaa
    13261 tttacaacga ctcttccaaa tatcccagct gacagcgttc ctgttggggc tgacgaagac
    13321 gacaatgtgg aagttcgccg ttggggtact ccacgcgagt ttgacttcga acctaaagct
    13381 cactgggatc tcggtgaaga ccttggtatc cttgactggg aacgcggtgg taaggtaaca
    13441 ggcgctcgct tcctcttcta taaaggcctc ggtgctcgtt tggaacgtgc tatctacaac
    13501 tttatgttgg atgaacatgg aaaagaaggc tatactgaag tcatcacacc ttacatagtc
    13561 aaccatgatt ctatgtttgg tactggtcag tatccaaaat ttaaggaaga tacttttgaa
    13621 ctcagcgata ccaactttgt cttgattcca actgctgaag ttcctctgac aaactactac
    13681 cgtgatgaaa tcttagacgg caaagatctt ccaatctact tcactgccat gagtccgtca
    13741 ttccgttctg aggctggttc tgccggtcgt gatacgcgtg gcttgatccg tttgcaccaa
    13801 ttccacaagg ttgaaatggt caaatttgcc aaaccagaag aatcttacga agaattggaa
    13861 aaaatgacag ccaacgctga aaacattctt caaaaactca accttccata ccgtgtcgtt
    13921 gctctctcta ctggagatat gggcttctca gctacgaaga cttacgactt ggaagtgtgg
    13981 attccagcac aaaacaatta ccgtgaaatc tcaagctgtt caaacacaga agatttccaa
    14041 gcccgtcgtg cccaaatccg ttaccgtgat gaagcagatg gcaaggtgaa actccttcat
    14101 accttgaacg gttctggact tgcagttgga cgtacagtgg ctgcaattct tgaaaattac
    14161 caaaatgaag atggttctgt gaccatccca gaagcacttc gtccatacat gggtggagct
    14221 gaagtcatca aaccataaaa aataaggttt agctatttct agctagacct tttttcgtaa
    14281 ccaaatcaga taagcaccta gtacaaagaa taaaatagtt aggcatataa tggtttcagc
    14341 caataccagg taatccagaa atggaagttt caaaattccc tgagccatct tgagcgaggt
    14401 cgctgtgata atggttggga aggtgagggc tgagaaggct ggttgaaaac cttgttttaa
    14461 aatgttgggc agacgagtta aaacaaagaa aaagaaggat tgagaagcca aaatcatgac
    14521 aatcaagacc caagtcggca ggctggttcc tcctactcga actagagaag ccaagagtag
    14581 agagaaagga gcacagtaga ttccttcttg tccaagcaag gctagtggga gtggatgttt
    14641 ctttaaatcg ctataaataa ggggatagag atagaaggtc aagagaaaac caaaactcaa
    14701 ggtcgcatag gcaatttcga taatacctac cagaggatag gtcaaggcag ccactgctat
    14761 ccccacatag agaaccgtcc agcttggagt ggcatgaacc ctccgctctg gacaagcaaa
    14821 cttgatggta aaaccagcaa tcaaggtcaa atccaagaga aatgaaaacc accaaatccc
    14881 ttgtgctacc aaaggaagat aagagaatac gcgaaagaca taggtcgata aaatcatccc
    14941 agccatagga aaggttgcca ttcctgacaa aagagggggc ttggtcaatt cttgcttggt
    15001 ttctttccaa ttaaagagat gcagaattag aaagtaaatc cataaaacca aaccagtcag
    15061 actaaaaaga tgggatagaa ctggcaacat atctaaaata agatttccag ctcctgccaa
    15121 acctagcaaa caacctgaaa atactaaggg gagttttttc atcctaacct ccaataatca
    15181 tgttagtttc agtataacat aaaagcgctt aaatgaggat ttaaaaaaac gaagtccgat
    15241 tatttcagac ttcattttac tcagatatga attaggcata aggttgcaat tctggattaa
    15301 ttggtgtatt agctaagttg ttggcatagt tacagaggat tgctaggctg acaccgaaaa
    15361 ccacatccaa ggcattttgt tgagtgtagc cagcttctaa aaactcagac aaggcttcat
    15421 ctcctacacg acccttggta ttgataactg ccaaggtaaa cttagctagg gtatccaatt
    15481 taggatctgt ttcaattgga gtacgattgc gaagagcttg aatcaagtca tcattcatct
    15541 ggatttgttt gatggaaaag gctgtgtgac ctgcgacaca gaaggcacaa ccattggtca
    15601 cggctgccgt gatttgcacc acttcacgct caacgggtgt caggctgttg cgacggtgga
    15661 tagatgagac aatttggtag gcttctaaaa cagtcggggc attggccaag agaccgatta
    15721 ggttgggaat atagccattg ttgtcttttt ctactgtttc aagaatttct ttcacttctg
    15781 ctggtgctga ctctactgta tggatagtaa atgttgtcat aagatacctc ttttcttatt
    15841 attgacacta atattattgg aaaatcttat aaaatcctga ttcctaagtt tatctaagat
    15901 aaagctttat tctctcataa gattttcgtt gttatattag tttatcacac ttccaatcac
    15961 ttgcataata tatattatat atcaggctga taaaaattat ttataggcaa aaaaatcaca
    16021 cgagctgtgt gattccatta tttgtcaaaa tactttttag tttcagcaat aacgactggc
    16081 gacaagacca agagggcaat caagtttggc agagccatca aggcgttaac gatatctgcg
    16141 ataatccaga ccatatccaa ctcgataaat cctcctaaca agaccatgag cacaaaaacc
    16201 acacggtaga gccagataaa gcgaacccca aagaggaact caaaacagcg ttctccgtaa
    16261 tagttccaac ctagaatcgt tgtaaaggca aaaagtacaa ggaagatggt caagagggca
    16321 ggcccaaagt gtgaaaagac tgttgagaaa gctgactgag tcaaggcaac cccattcaag
    16381 tcaccactcc aaactccagt taccaagatg gtcaaaccag ttagagtaca aatgatgagg
    16441 gtatcaataa aggttcctgt catggaaatc aaaccttgct ctactggttc atttgtcttg
    16501 gcagctgcag ctgcaatagg agcagaaccc agaccagatt cgtttgagaa cacaccacgc
    16561 gccacaccat tttgaatagc catccgaacg ctagcaccag caaatccacc taccgcagca
    16621 aggggactaa aagctgaggt aaagactaaa gcgattgtgc cagggatttt tccgatatta
    16681 aagaaaataa ctataagagt tcctaagata taaatgatgg tcataaaagg aacaacagta
    16741 gttgaaacct tagaaataga cttgagtcca ccaaagactg caatcgctac aaagacagac
    16801 aagacgagag ctgtgatgac tggcgaaatc gtcgttgtat tttggataga ttctgtaatc
    16861 gagttgactt gggtgaaggt tccgattccc aagagagcaa ccaatactcc tgctactgca
    16921 aacaaaacag caagtggtcg ccacttttct cccatcccta gaaggatata gtgcatggga
    16981 cctcccgcta ctgcaccatg gtcgtccttg gtgcggtatt tgatggccaa gagtccttcc
    17041 gcatacttgg tagccattcc aaagaaagcc gccatccaca tccaaaatag agctcctggt
    17101 ccaccaacct tgatagccgt cgcaactcct atgatatttc ctgttccaac agttgatgcc
    17161 aaggctgtac acagagctgc aaaactggat acatcaccat gtcccttatc ctggataaaa
    17221 ataagctgaa aggccttggg cagacgcaaa acctgcaaga gtcctagccg catggttagg
    17281 taaatccctg ttccgaccaa taaaatcaag aggggcggtc cccaagcaaa atcatcgatt
    17341 gatttaagca attctaacat ttccttctcc tatcgtttca accccaaaag aaagagcaca
    17401 tgcaagatac atgtactctg gaatgcttag ataaatgcta aaaagcggtc tatcctagct
    17461 ctgtcctttt acctgagagt ttgagcagtt gcctgccttg ccccttcggt gcctttacgg
    17521 tctctccaga gttccgtcca tttacagtca tggaaaatca aacgattccc cacttctatt
    17581 aaacttcatt cggtgttggt atttaattga ttctaatttt acaaaaaatg ttggcttttg
    17641 tcaatgtgtt tattagtaaa aattagttca acagttttta ctttataaag tccagaatac
    17701 tgctatcctt taaaagtgac aatagtcgca ccactgcctc cagcattttg tggggcatag
    17761 ccgaaactct tgacatgttt gtttctttgc aagtatttgg taactccttc acggatgact
    17821 cctgttccga taccatggat gatatcaact tgagccatat tgttaagcaa ggcttggtcg
    17881 atgaaggtat ctagctcatt catggcttct tcatagcgct tgcctcgaag atccagtcta
    17941 gcttgaggtc ctcgcccaga agttcgtttc acaacattga cctgtttctt cttgactggt
    18001 ttttcttgct gggcttgaac aagatcaaac tctttctctt ccaaggtcat cttaatcaag
    18061 ccaacttggg cttcccagcg gccgtccttg agttgactgg tcaaggtacc acgctgacca
    18121 taactgagaa ccacgatatc atctcccacc tttggagctc gttttttctt ggccttttga
    18181 aggaccttgt ttttagacaa gtccactttt tcaggagcca attttttcaa cttggccttg
    18241 gcttcaatga tttcgtgggg cttgagttgg gatttactgt ggagattttt gagaatctgg
    18301 tcactttcac ttagggccat atccacaatc tcagcagcct gttcacgcgc cttgttaagc
    18361 tcggtttcct tttcacgatt aagctcgttg tagagttttt ttagcgcacg gttcatcttg
    18421 agattttctt gctccacctc acggatattg tccaaacgtt tgcggctttc cagcgtctgc
    18481 tcttctaatt gctcaatgat acgattgacg tcattgtcct gatcgatctg ctgactggca
    18541 tctcctacga taacttcaga taggcctaga cgtttggcaa tttcaaaggc attacttcgg
    18601 ccaggaacac cctgcataaa gcgataggtt gggcgaagag ttgcagtatc aaactccata
    18661 ctggcatttt gcacaaaggc tgtctcaata ccgtaggcct tgagttctgg atagtgggtc
    18721 gtcgccatgg tcttgatttg acgcaggcga aggtcctcca gaatagccat ggcaagggct
    18781 gctccctctt ggggatcagt accagccccc aactcatcca aaagtaagag tgaatgttgg
    18841 ttgaccttgc caagaatatc cacgatattg gtcatatggc tagagaaggt agacaagctc
    18901 tgctcaatag actgctcatc tccaatatca gcaaagattt cttcaaaaat accaacacga
    18961 cttcccttgt ctgctaaaat cggcaatcct gactgggcca tgacctgtgt caagcccaga
    19021 gttttgagca tgatggtctt cccacctgta ttgggacctg taatgacaat agctgttaaa
    19081 tcttgaccaa aatagacatc atttgcgacg gcatttttga ccaaaggatg gcagacatgg
    19141 agcagttgaa tctcttgatt ttctgacagc tgaggcacga ctgcttgtct ttcttggata
    19201 aatcgaacct tggcacgaat caagtccaga tgaccgataa tccaagcgtc attagcaatc
    19261 tcagccgcat gagggcggac acgctcagaa atttcttgga gaatgcgaag catttcatag
    19321 cgctcatctg ctcgcagact agcaatttct tcgctcagtt tgactacctc acgtggttcg
    19381 atatagacgg tgtttccact agcagaaata tcatgaacga cacctgcaat cttattgcgg
    19441 taggtgtttt tgactggtaa aacctgacgg ccatttctgc tagcaacaat tccttccgtc
    19501 aacatctgcg ctttttgctt gagtaagtct tgtaaaacat cgcgcacctg actctcgcta
    19561 tcatgtattt ttcgacggat tcgcgccaat tcttcactgg caaaattttc aatgaaaccc
    19621 gcatcattaa aggcctgaag atttccttgt aattgcggaa aatcatgtaa tttctcaaac
    19681 caaagggcta attcttccaa gctgacattt tccagattgg cgtaaaaatt ttgaagttct
    19741 cggctggcaa gaagcacgcg tttcaagagt aggaactcct cgatattgag atccgctccc
    19801 atctccaacc tcttgcagac tcctgcaatt tccttagttg agagaatagt aaaatgcggt
    19861 tgctcgacga aaagagcctg catttctttc atctcagcaa aagcctgttt gattttatct
    19921 gctttggcag tcggagccag ctgtctcaat tgctccaagc cctgctcggt caacaaatga
    19981 ggctcaaaca aggccttgac cttatcgaac tctaatgttt ctaatatttt cttattcatc
    20041 tttatttcct tgtctttgaa tgtctaggtg tggtagcttt ttacattctg atagattcga
    20101 gtcaaatctg taaacaaagg gctaggaaaa ctcctgccct ttttatccga ttaaatttgt
    20161 cacccagatt tgtttgagcc aactggttgt tatcggtatg ctctggatga tgtgttttgc
    20221 gacgatactc ttttcaagag gattttgtat aactgccatg gggatggtcg ccaagattgt
    20281 caaggccatt tgcaagacaa ataaggtcac caacatggac aagatacctg ctgaaacttg
    20341 gaacaactta ccacccagtt ttttgctagg aatcaagtgt aagagaagac caagcaaacg
    20401 accaatacta tagacaatcc caaatacaag caagtagccg atacctgcat aaaagacctt
    20461 atccagctga aagagttgat ccgatgggaa aaagaaagtc ccctgacctt cctgcgaatt
    20521 tgcataaggg agcaataaat ggaattgctc tccaagcccc ttataaaact ggccagccat
    20581 aaaagccgat gccatggctg aaatcaggta ataaacctgt aagagcaggc ctctccgata
    20641 gccgatataa aatccccaaa ccaagaccaa tagaagaagg aatgaaatca taaggaatcc
    20701 tcaatcttgc tctgttcttg cttacaagtc acaagcttgt gacggagttc ttctagctct
    20761 tgctccttag cgtcaaattc aatctcacgg ctgagctgag ttgataaaca gttgactgcc
    20821 aacaaaagag cgattgtttc atcatctgcg ctaggcattt gttctttaat tgcttggtat
    20881 ttttctgtcg caaccttagc gatttcctcc ataaaaaggt tatcatgttc gcttgtcaag
    20941 gttaacgttt ttttcccgaa tgtaaatttg aatcgattta gatttgccat aaaattcacc
    21001 tcacgatatt ataccaaaat tcgctaattt tgtcagtttt tacaaatttt actgcttttg
    21061 tggtacaata gaaactatgg caagtatcac actcacacca agcgaaaagg atattcaggc
    21121 ttttcttgaa cactatcaaa ccagtctggc tcctagcaag aatccctata tccgctactt
    21181 tttgaaacta cctcaagcaa cggtttctat ctatacttct ggaaaaatct tgcttcaggg
    21241 tgaaggggct gaaaaatacg ccagtttctt tggctatcaa gctgtagagc aaaccagcgg
    21301 acaaaatctt cctttgattg ggacagatga ggtgggaaat ggttcctact ttggtgggct
    21361 tgcagttgtg gctgcctttg tcacacctga ccagcacgac tttttacgaa aactcggtgt
    21421 gggggattct aagactctga ccgaccaaaa gatccgtcag attgctccta ttctcaagga
    21481 aaaaatccag caccaggcac tccttctctc acccagcaag tacaacgagg tcatcggaga
    21541 ccgctacaat gctgtttcgg ttaaggttgc cctccataat caggctatct atctcctcct
    21601 tcaaaaaggt gttcagcctg agaaaattgt gattgatgcc tttaccagtg ctaaaaatta
    21661 tgacaagtac ttggcacaag aggccaatcg tttcagcaat cctatcagct tagaagaaaa
    21721 ggctgagggc aaatacttgt ctgtcgcagt ttcttctgtc attgcgcgtg atctctttct
    21781 ggaaaatctt gaaaatctgg gacgagaact gggttatcag cttccaagtg gagctggaac
    21841 ggcttctgac aaggtggcta gccagatttt gcaagcctat ggtatgcagg gactcaactt
    21901 ctgcgccaaa ttgcacttta aaaacactga aaaagcgaaa aaacgcttag aaaggtaagt
    21961 tatgaattca tttaaaaatt tcttaaaaga gtggggactg ttcctcctaa ttctgtcatt
    22021 actagcttta agtcgtatct ttttttggag caatgttcgc gtagaaggac attccatgga
    22081 tccgacccta gcggatggcg aaattctctt cgttgtaaaa caccttccta ttgaccgttt
    22141 tgatatcgtg gtggcccatg aggaagatgg caataaggac attgtcaaac gtgtcatcgg
    22201 aatgcctggc gataccatcc gttacgaaaa tgataaactt tacatcaatg acaaagaaac
    22261 ggacgagcct tatctagcag actatatcaa acgcttcaag gatgacaaac tccaaagcac
    22321 ttactcaggc aagggctttg aaggaaataa aggaactttc tttagaagta tcgctcaaaa
    22381 agcccaagcc ttcacagttg atgtcaacta caacaccaac tttagcttta ctgttccaga
    22441 aggagaatac cttctcctcg gagatgaccg cttggtttcg agcgacagcc gccacgtagg
    22501 taccttcaaa gcaaaagata tcacagggga agctaaattc cgcttctggc caatcacccg
    22561 tatcggaaca ttttaagaga cctaagaggc cgagaatcac aaatctcagc ctcttcttct
    22621 atcgtgagaa gtgattgttt attgacaaat actcaatgaa aatcaaagaa caaactagga
    22681 agctagccgt aggctgctta aaacagtgtt ttgaggttgt ggatagaact gacgaagtca
    22741 gctcaaaata ctgttttgag gttgcagatg gaagctgacg tggtttgaag atattttcga
    22801 agagtataaa ataaaaacaa tcccaactct cacctattca tgcaaaggaa ttttatggaa
    22861 gtttattttt caggaaccat tgaacggatt atttttgaaa atcccagcaa tttttatcgc
    22921 atcctcctcc tagaaatcga cgatacggac gcagaggatt ttgatgattt tgaaatcatt
    22981 gtcacaggaa ccatggctga tgtaattgag ggcgaagact atattttttg ggggcaaatt
    23041 gtccagcact ccaagtatgg agaacaactg caaatcagtc gttatgatcg cgcaaaacca
    23101 actagtaagg gattggtcaa gtacttttca agtagccatt tcaaggggat tggtctcaag
    23161 acagctcaga aaatcgtaga tacctatggc gaaaatacca ttgatgaaat tttgcaacac
    23221 ccagaaaagt tagaaggcat cgcaggactc tctgccaaaa atcgcgaggc tttcgtctcc
    23281 actctccgtc tcaactacgg aacggagatg gttttggcca aactagccaa ctacggcatt
    23341 cccaacaaac tagcctttca gattcaagac ttttacaagg aagaaaccct tgatgtggtt
    23401 gaaaattatc cctaccagct ggttgaggat atcaagggtt tgggctttac aattgctgac
    23461 caactagctg aggaactagg catcgaaagt caggctcctg aacgcttccg cgccggtcta
    23521 gttcacagtc tttttcaggc ctgtatggaa acaggggaca cctatgttga agcacgggat
    23581 ttgctggaac aaacccttac tctccttgag tcttcccgtc ccgtggaact agaccccagc
    23641 caagttgccc aagagctctc ctacctgatc gaagaagaca aggttcagca gattgatacc
    23701 aagatctttg acaacagcct ctttttcgct gaggaaggca tccgcagtca cttggttcgt
    23761 atccttgaaa aaggaaaaca gaagagtcat gatttagaaa ccattcaaaa acatatcact
    23821 actatcgagg aagagctggg aattgagtat gataacattc aaaaacaggc tatctgtgac
    23881 gctatccaga acaaggtctt tatcctgaca ggtgggcctg gtactggtaa gacaactgtt
    23941 atcaatggaa tcatcgctgt ttatgccctt ttagaaggac ttgacttcag gaagaaaaac
    24001 aatctgccca ttcttcttgc tgctccaact ggacgagccg ctcgccgcat gaatgaattg
    24061 acaggtttgc ctagcgcgac catacaccgc cacttgggaa tgacaggtga cgatgatacc
    24121 agtcatctgg aagattacct agatgctgac tttatcatcg tggatgaatt ctctatggtg
    24181 gatacttggc tggccaatca actcttctcc aatatctctt ctaacagtaa gatcctcatc
    24241 gtgggtgaca gtgatcagct accttctgtc agtcctggac aggttctagc ggatctgctt
    24301 catattcctt tgattcctca gactcgcttg gaaaaaattt atcgacaaag cgaagaatca
    24361 accatcgtca ccctagctag tcagattcga caaggcatct tgccagctga tttcacccaa
    24421 aaaaaagctg accgttccta ctttgaaatt gctagtggcc atattcctgc cactattgaa
    24481 aaaatcttag atgccgccct cagaaatggt attcctgccc gtgatatcca agttctggct
    24541 cctatgtacc gagggacggc agggattgat gctatcaatc agctcatgca agacctgctc
    24601 aatcccccac aaaaagatca actcagtttt gaagctcctc agtgccacta tcgtaaggga
    24661 gacaaggtca ttcatttggt taacgatgct gaaatcaatg tctttaatgg ggatttagga
    24721 gctatcacag acctgattcc tggtaaatac accgaatcga aacaagacga gattgtcatt
    24781 gattttgatg gtaatgaagt ctcttacccc cgtaacgaat ggtacaagat tcgcttggcc
    24841 tatgccatga gtattcataa gtctcaggga agtgagttcc cagttgtcat cctaccgatt
    24901 actagtgcta gccgacgtat gctggagcga aatctcatct acacagccat tacacgtgcc
    24961 aaaagcaaac tcatcttact aggcgaatta caagccttcg actatgctac ccaacacatc
    25021 ggaactgccc gaaaaaccta tctgattgaa cgcttcagtg atctactgga gaatgttgaa
    25081 gaaaagcaac aagctgtctc tgaaacagtc acatcaagtg cctctgaaca atcctacatc
    25141 ctaaccgaag aaaactggga cagcattcca gccatgattg ggattacaga cacagacctc
    25201 aaagagattt ttggaaaata gtacatcaga aaacccacca attcaggtgg gttttctgtt
    25261 tattaagatt attttactgt tgctgtgctt gtgatcaatt caacagcttt tttgatagtg
    25321 atatcatgtt tcaacatgtc agctgaaagc aagttttgaa cttgtgcaac ttccatgttg
    25381 tagtctgctg ccaattgctc aacttctttt tggatttctt cttctgaagc atcaaatcct
    25441 tcagctttgg caactgcttc gataacaagg ttagtcttag tacgtgactc agcttctgct
    25501 tggtattggt tatgaaggtc ttcttgagta gttccagtga tttggaagta catgtcaggg
    25561 ttgatccctt gacgttgcaa gttcccaagg aattcattta ctgaacggtg aacttcttcg
    25621 tggatcattt cttctggaag ttctacgatt tcagcgtttt ctacagctgt atcaattgct
    25681 gcaccttcaa ctgcatcttt gtaagcttct tctttagcag cagccaattc tttgcggtat
    25741 ttttctttca agtcagcaag tgtttcaact tcttcatcaa tgtcttttgc aagttcatcg
    25801 tcaagagctg gaacttcttt agcttttact tcgtggatag ttgtcacgaa ttgagcttct
    25861 ttacctgcaa ggtcttctgc ttggtagtct tctgggaatg ttacgataac atcaacggtt
    25921 tcgccagctg agtgacctac caattggtct tcgaaaccag ggatgaattg acctgaacca
    25981 agtccaagtg agaagttttc accttttcca ccgtcaaatt caacaccgtc gatagaacca
    26041 acgaagtcga tcacaacagt gtcgccgttt tcagcagcag cttccttgat aaccaattca
    26101 gccaggttgt tgcgttcgcg ttcgatacgc tcttcaacat cagcgtcagt tacttctttt
    26161 tctacatcaa ctgatacttc aaggtttttg tagtcaccca attttacttc aggttttgta
    26221 acgacttcag cagtgataac ccagtcttga cctttttcca ttgaagttac gtcaattttt
    26281 ggttgggcaa ccacttcaag accagcttct tttacagctg cttcataagc gtttggcaaa
    26341 agagcgttca taacgtcttg gtaaagtgat tcttcaccaa attttttatc gaagatagga
    26401 cgtggaaggt gacctttacg gaaacctgga acattaagag atttcttcac tgacttgaag
    26461 acacggtcca attctggttt gatttggtct tgagagatag tgaaagtcaa gacaccacgg
    26521 tttgtttctt tgttttcaaa tgatacagac attctgtcat ttctccttaa aattttttaa
    26581 atacagtcta ttataacatt ttctataaat aaaatctaga ctaatgcaga caattataga
    26641 caacaagtct ttttcctaac taaaacactc ataaagtata gacaatttta gactactttg
    26701 gatatctttt ggttagtcat tttccaaaac taatttatct aatttttaag ttatatttga
    26761 cttcatcttc tcagtaacat gagtataaac acttaaaatc tttgtttcat tagtataatc
    26821 tacacgatcc attatcgcta ttataggtac ttccaattca gcaagcaaac ttatatgcga
    26881 atatctaaaa acatgagcag tcaatacaaa atcatctttc ttaatttcac ttttcctaaa
    26941 cctgtttttc aaaaagtaat tgaaacaagt tatcattaag ggagaaccat tatttgtaaa
    27001 tatataatca ccttcttcta aaagaagata ttcttttaaa atttctaaca ctctatcact
    27061 aataccaatt actctatatg aagctaaact tttcggacta tccaaaaaca cttcgttatt
    27121 ggacgattac attatagtaa aacgaaataa gaacaggaca aatcgatcag gacagtcaaa
    27181 tcaatttcta acaatgtttt agaagtagag gtgtactatt atagtttcaa tctactatac
    27241 aagacgaaat tgaagaaatc tttccattat aaaacgcata ttatcaaggt ttttaaacac
    27301 ctaataatat gcgttttttc ctattttaaa gacttttatc cacctattat acaaagttaa
    27361 gtatccatca cagtttacaa ttagccttca ttacctaacc cattcaccat ccttcaagag
    27421 agtaaccttt aagaaccgaa taaataaatg gcaaatttcg ttcatttaat ttaactgcac
    27481 tgttaatttg attagctcca tctcctaaag tatgcactcc tactacgcgg ttactagcat
    27541 cataaactgt agatccacta gacccctcta aagtatcaac ttggtagtcc aagaacatgc
    27601 catcatcact taaaacttgt tttttatctg tatacatttg atgaatttta aaattatatg
    27661 atggatagcc tgtgatagtc acagttattc ctgtcaaatt tttttgacta gtaggaagac
    27721 ccaaagtccc taattttgca ccaatgggct cttctagaat taataaagcc aagtcatatt
    27781 cccttgcatc cttagaattt aaatttctaa attcctttaa ataacgaact tcttttactt
    27841 ttatccgacc aaacggcaca ctatttggag tacgagcagg agtaacatat agttcttctg
    27901 catctttacc aaactcatgt ttataaatat tatgagcagc agtaataagg acattatcct
    27961 ttataaaatt ggcactccct cgataagtta catctttacc atttttcaca ccacgaaatt
    28021 ctgactctac ataagctgat gtagaataag gatattgtaa agtatttttt accttaacta
    28081 aatcattttt accaataatg acttctgact gatttgtata atattgacca taagtcggtg
    28141 aaacattggg aagtgaaaaa ttattagttc ctggactatc ttgtaatgtc tcacttacct
    28201 catattcttc acctgtacta gaaataacac tcaaagcaga tactgtcgat aactggctag
    28261 ccaataaagt actcgcaata attgaaatac ccaatttttt ataaacagtt ttcttcatta
    28321 ttgtatcctc ctaatgtaat tatagcgtac tattctaaat ttcttaatct actatagaat
    28381 caagaaatct accaccttct ttaaataccc tccattatca cataaacagg taaacttttc
    28441 aattaatgac tgcgcttttc aatcacgcta gaggtactta cttgcttctt tgatactaag
    28501 ttcagccatt ctttccttgt ttttctcaat aaagcatgtt acccaagtgg gattcgttct
    28561 ggtggtcaat agcgacacgt ctcagccaga tattatctga taggctccat tttatactca
    28621 atgaaaatca aagagcaaac taggaagcta gccgcagatt gctcaaaaca ctgttttgag
    28681 gttgcagata gagctgacgt ggtttgaaga gattttcgaa gagtattaag attatttctt
    28741 ctagttcaga gtgttcatac accaaactcc ctactactcg atctaggata tctaccgtgt
    28801 cccaccagga ttttgtcacg actaactgct ctagcttagg caaatcggtt tcctttagat
    28861 aagactgcat tgctttcaaa tagttagcag ccacatattg gtattctcta ggatcctttt
    28921 cccagcaagt gtctgcaaaa tcccaatcga taatctttgt ttttttcgct tctggaaaat
    28981 atttttatag agtttatttc tttcaggcac cgcaatacct agaaaagaaa attgatggcg
    29041 catataggct tccatggacc ttgctttttt agagtctttt gctgcttcta gctcctcaag
    29101 taaatctgct aaactcatct aaaactcctc ttgccccacc aaatggtgct gaaaggcata
    29161 gacagccgcc tgggtacgat cgctgacttc aagtttggca agaatattgg acacgtgggt
    29221 cttgaccgtc ttgagagaga taaagaggtc atctgcgatg cgctgatttt cgtagccctt
    29281 ggcgatgagt tggagaacat ctcgctcacg cgcagtcaat tcttcatgaa gttccatatg
    29341 attgcggtgg tattcaacct tcttgctaac ctcttgctca atggccagct cgccagcagc
    29401 taccttactg acggcatgaa gcaattcatc tgcactagaa gtcttgagca tatagccttt
    29461 ggcaccagca tctaagactg gcatgatttt ttcattgtcc aaataagagg tcacaatcaa
    29521 aatcttggct tcaggccatt ctttaaggat tgctaaggtt gcgtcaatcc cattcatctc
    29581 aggcatgaca atatccatga caatgacatc tggacgcagt tccaaggcca agtcaatccc
    29641 ttgagacccg ttggacgcct cacccacaac ttctacatcg tcttggaggt caaagtagct
    29701 tttcaagccc aatcggacca tttcatggtc atctactagt aaaattttca tctttactcc
    29761 tttatcattc cttatctaac aggggaatac ggatatcaac cgccagccct tgcttgggag
    29821 ctgtcaagag ttgaactgtt ccagccatat cttcaatccg ctccttgata tttcgcagtc
    29881 cataactcaa gtcgtctaag ctccctaact ggaaaccaat cccattgtcc accaccttca
    29941 gttgcaattc aacatctgtc tgatagaggt agacatctag gcaagatgcc tgggcatggc
    30001 ggagcgtatt gctaatcaac tcttgcagga tacggaagat atgctcctcg attttcttag
    30061 gaaatttcgt catattctgc ttgagactaa ccctaagatc actcttgtcc tcaagctctt
    30121 ttaagagaat ttgaatccct tctatcaagc tcttctgctc cagttcaact ggtcgcaaat
    30181 gcaagagcaa aacccgcaaa tccttctggg ctgtttctaa aatagctgtg acactctgca
    30241 actgggtctg catcttttct ctatccaatt tcaaagcctg ctgactgata cccgataaaa
    30301 tcatgtgggc cgcaaacaac tcctgactga ctgtatcgtg caaatcccga gcaattcgct
    30361 tccgttcctt ctcgatgatt tcctcttcct gagcaaggct atgattttca gctttttgaa
    30421 gagcctctgt caaaaggtta agtttacctg ataaggactt gaaactggca tccaaatctg
    30481 gatctgcaac ctgaaccact tcttgccctg ccaataaacg cttgagatta gcctgcattt
    30541 ttcttagaga aagctcttcg atccctcgcc aaaacagggc taagagacag gttatggaca
    30601 tgctgaaaac caacaataaa aagacaaatt tttctgtttt ttcgacatcg tgcaaaaaga
    30661 tagaccagtc aaaatcaagt atttccagca agctgtggga gaaaaaaaag acaaacagga
    30721 aggaggtgag agcaataatg acataggctt gttttttcat cctctaacca cctccacatc
    30781 accaatcata gtggtcaaga aaatcttgac actcttgtta ctcttgagat agtcttttgt
    30841 ttcttgatga tagtgttcat tgcggagggc tcgcttgggc tggttgaaaa aagtcaaatc
    30901 cccatagaga cagttaacgc tgagactgac ttccacatct acaggtacga tgattttggt
    30961 cgttcctacc atctttctga ggataatgac attgtcatga ttggttaaga tgaccctctc
    31021 cagatgaata gtgtccttgc ccatgaagcg aaagagattg atatcatcga attggcaagt
    31081 ctggtagctt gaaaaatgat gaagatttcc aaaccaacga tttttctcct tcttaaccgt
    31141 cacgacctct tcaaaaacca aattggtctg ctctttttcc tggttcatca tcgggtaaag
    31201 aagaaagagg ctatagataa ccgcaacaaa aatagctaga atcacaaaag gattgagcat
    31261 aacgatgaaa aagaagagaa tggttgccgc tactaaaaga agattatttc cctctttacc
    31321 agtgtagtag cgaatcaaaa gcaaaaagag gaatagtatc agcagaaaac gcgaaaaatg
    31381 ctctgatacc atcaaaatca gagctcctgt cagaagacag gcttcgataa ataaaaagat
    31441 tttaaatttt ctcataggtt catcctctcc cttctatttt atcacaattc aaaaaagtca
    31501 cctcagtctg aggatggaaa aaaggcgctg gttacgcctt tttcatctga tcctttgctt
    31561 cttttaattt tccataaaga agatagtcta ctttttgtag atctgctatg gtggcacagt
    31621 taagggaaca cataatcaag cgtaggtctg ctttccagcc ttggacaatg ccaatcactt
    31681 cttcaactgt gtaggtttca accaattcca gaacggttcg tgacaatccc acagacttag
    31741 caccaaaaac caagcactta atcatatcca gcggattccg aacccctcca ctaaccaaga
    31801 gttcgacctt atctttccat tcttgggcat tgagaagggc ctgcatggta gactgacccc
    31861 attgattgag gtaatcacgc tggccactac gacggttttc gatataggca aagctggtgc
    31921 caccacgacc cgataggtcc actgtacgaa caccgaattc ataggctctt tcgattgtct
    31981 tggcatccat tccaaagccc acttccttga ggacaatagg aacgggaatt tgctcgctat
    32041 aatctgctag atgcgattgc cagcttctaa acttcctttc tccctcgggc atgagtaatt
    32101 cctgcatgac attgacatgc acttgcaata gaacaggatt catctcttct acagtctgaa
    32161 gtcctaactc gacaggcttg tccaatccaa tattggttcc aaggaggaga ttgggatgac
    32221 tagacttgac agaaaaagaa tcatccgttg gatttttgag ggctgcgcta taagaacccg
    32281 ttacaaataa aataccacag gattccgcca cctgagccag cttttgattg atttctcttc
    32341 ccttattact tccaccagtc atggcattga tataaaaagg aaagtcccac tttcgaccag
    32401 caaactctgt cgaaagatcg atttcatcca gattgtaaag aggcaaggaa gaatgaatca
    32461 gctccacctc atcaaagcta ttataggaac ttttctgctc aagggcatag aggatatgct
    32521 cgtccttacg atttgtcgtc atgtcctatc ctttcttgat ataagagctc aatccccaga
    32581 tcggcccaac gattttttaa ggttttggtt gattgcgcat caaaactcaa ggcgatgcca
    32641 cagtcaccac caccagcacc actactcttg gcaacggcct gcaaatcttg actggcttct
    32701 ttcaactgtc taagcaaagg cgtgtaaata tctgtactca agccttctaa aagcttgctg
    32761 gctacttcta cttgctcgat aactttttcg gctttcccct gctccaaggc ttcgaccaaa
    32821 gaaaccaccg tttcttttga ggaacttaaa aaattttgat tgatattttg cttgatttgc
    32881 tggaccatgt gactcgatac agccacttcc ttggtccatc ccactaagaa atcacattct
    32941 aaagttggtt tcacttgtga gataaaaaat ccccaatcac gctccagaac tgtcgccaag
    33001 ttttcttctt ctaaccaagc agccaccttc tggcgatcaa atgactggta gagaaccaaa
    33061 tcctctgcca caatacaggc aaggtcgccc atggaaccat tgtctcctcg cttgagcaag
    33121 acagcgctag tcagcttgaa caagagattc tgatcaaccg aaagattata gagagccagt
    33181 aaagccttga caaccaagac aacgacgctg ccactagaac ctagaccaaa ctttttccct
    33241 tctcgttcca ttttgccaca gatttttagg gaaaaaggtc ttaaattctg accgcgaaca
    33301 gcgaggaagt ctcccatcaa agcaatcgtt tcttgaatca agctgtagtc aggattaggc
    33361 cttaagtcca ctgcgaaatc aaacatatct gaatagatac ggtagctgtc agaaaaagca
    33421 atttcagccc tcatatagat gggaatatcc tttatcaaag ctaactgccc tggctctaaa
    33481 atagcatatt cacctgccca atagagtttt ccgcaagttt taacagcaat catcttgact
    33541 caaatccttt gtttttgaca caatcaagcg ataacgctga ccgaaaattt ctgataaatg
    33601 ctccaagtct ttctcctgac agaagacctt aacattggga ccagcatcca tggtaaagta
    33661 gcaggcctct cctttctcac gaagctggcg aacaaagtcc atagcctcat aagaggcatc
    33721 cgtcagataa gaaaaggctg gactagcagt ctttgtcgta gcatgcatag ccagggcatt
    33781 tttctccgtt aattctccaa tcttggcaaa atcattttcc ttgagataaa tcagcatatc
    33841 ctgatagtcc ttctcagact gacgaaccca gtcgtcgaaa gtcgtcgagg tttccacaca
    33901 aagtttcatc ccgtcacggc tagagattgg ttttttcttg tcctctagca ccaacataat
    33961 catagctagt ttcaagtctg tctctacagg gtaaatttct ccactatcct tatcccaggc
    34021 tcctagtggt ccataaaaac tccgagaaga agagcctgag gcaaacttgg cttcctgcgc
    34081 taactgactt ctatccaatc caagcttgaa ataagcatta caagccttga ccagggcgga
    34141 caaaccacta gaacttgagg acaggcccgc tgccgtaggc atattgtttt gagtatcgat
    34201 acggacaaag ccctcaccag ctggacgata acggtcaata atcttactca tcttggcatg
    34261 ctcgacctca ttttgtagct gaccattgat gtaaaattcg tcagctgtta cattggctgg
    34321 taaaggcgac aaggtcgtct ctgtatacat attttccaaa gttagagaaa tactgctagt
    34381 agcaggcacc atctcttttt cttttttctt tccccaatat ttgataatag caatatttgc
    34441 gtaggaacgt actgttacag gctctctatc catgtctgaa cagctccttt ctcttctaat
    34501 ctttctgcta gttcttgtgc gtgtgtcaaa ttggttacca aggctatgat acaacctcct
    34561 agcccaccac cgctcatctt ggcacccaga gcaccatggc taagagtcgt ttcaaccaaa
    34621 aagtctgcct cagggctact gactccaatt tcttttaaat gtaaatgcgc ttgactgagg
    34681 atttgtccca gtccttcagc atctttttgt gaaatcgcaa cttctgcttg ctgggttaat
    34741 tctcccaagg catgcaaaaa cggtagggca tccttgccct tattttgaac cacttggatg
    34801 gcttcacgag tatgaccata aacacccgta tcggcaatca ccaaataggc ggataaatcc
    34861 atctcaagtt ctgtaaatcc tacgttcttg ataaagcgaa taggttggtc actgagacag
    34921 gtcttagcat ccaaaccact aggattcata tgggcaatca tttcagctcg attgaccaag
    34981 atttctagta catcatgagg cagatcagcc tgatagtagt caaataccgc acgaatggcc
    35041 gctatgctga tagccgctga cgaacccatc ccccgtttct cagggatagc cgagtcaatc
    35101 tcacaacgaa tgcaggcttc tgtgatatcc aaatactcca gtgaggcata aaccgccatg
    35161 gacaaggtat cctcctcata aaggcgccaa ggactctctg caggaactac cttacaggtc
    35221 acctccacct ccaaaagagg cagggaaatg gcaggataac cgtaaacgac cgcatgttcc
    35281 cctattaaaa ttatcttact atgtgcctga ccgacaccaa ctttttttgt cattttttcc
    35341 ttttactaga cgaaaaaacg tcttattttt catacaagta ttaattcttt cctatctatt
    35401 ttattatatt ttcacaaaaa aagcgattgt ttccattcac aatcgcttct ttcattaccg
    35461 aacccattca ccattataat tgacagaata gccatctaca gtcgtattca ctgccaaggc
    35521 acctgagcta taagcgtagt accatctgcc attgacctgg aaccaacctg tcgtcataga
    35581 acgatgaaag aaactccata ccattaagta aagaggaaag tcatgaggga gcatgcgcca
    35641 ttgacaacct gttttagtga cgtacaaagt ttcattaaca agtactcgtt tcggccattt
    35701 ataggtgcgg tgtttgcaga aatagggttc aatcttcgcc cattcttgat cgtttaaatc
    35761 agtatcatat gctttgcgtg tcataactct agtttaacat ttttttgtga atacaggttc
    35821 taaataatcg accacgaaaa tttcttaagt ggaaaacgcc ttatgaagta tgctacggga
    35881 aacttatgca cttaatttga caactcaata tgtaaaaata tatactata
//
LOCUS       DAVLMQ010000017        33553 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000017 DAVLMQ010000000
VERSION     DAVLMQ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33553
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.017"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(246..608)
                     /locus_tag="VXF95_001015"
     CDS             complement(246..608)
                     /locus_tag="VXF95_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HEV1081583.1"
                     /translation="MLEVGLNFLISLFTFTFDILYPIVKVGHTDDYSHGAVKLSVSLV
                     DKDAMKKISVTVIGYFEINIDENITDILYVNGTAILYHYLRSIVSIVSAIDSSEAMLL
                     PTINVLELLDKSQPFEEE"
     gene            622..696
                     /locus_tag="VXF95_001016"
                     /pseudo
     CDS             622..696
                     /locus_tag="VXF95_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(944..1081)
                     /locus_tag="VXF95_001017"
                     /pseudo
     CDS             complement(944..1081)
                     /locus_tag="VXF95_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(1459..2148)
                     /gene="rplA"
                     /locus_tag="VXF95_001018"
     CDS             complement(1459..2148)
                     /gene="rplA"
                     /locus_tag="VXF95_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HEV1081584.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
     gene            complement(2356..2781)
                     /gene="rplK"
                     /locus_tag="VXF95_001019"
     CDS             complement(2356..2781)
                     /gene="rplK"
                     /locus_tag="VXF95_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HEV1081585.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFITKTPPAAVLLKKAAGVEKGSGTPNKTKVASVTR
                     AQVQEIAETKMPDLNAANLESAMRMIEGTARSMGFTVVD"
     gene            complement(2904..3620)
                     /locus_tag="VXF95_001020"
     CDS             complement(2904..3620)
                     /locus_tag="VXF95_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HEV1081586.1"
                     /translation="MKKRYVILSGLLALTLAACSQEKTKVEENTQKTEQSSQPEGTVG
                     SKSQASSQKKAEVSNKGSYYSIQGKYDEIILANKRYPLSKDYNPGENPTAKAELLKLI
                     AAMQAEGYPISDQYSGFRSYETQAKLYQDYVNQDGKEAADRYSARPGYSEHQTGLAFD
                     LIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            complement(3638..4099)
                     /locus_tag="VXF95_001021"
     CDS             complement(3638..4099)
                     /locus_tag="VXF95_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1081587.1"
                     /translation="MCLICQRIELIKAGQNPYFVKELETGYVVIGDHQYFKGYTLFLA
                     KDHVTELHHMETSVKLRFLEEMSLVQEAVAKAFEAEKMNIELLGNGDAHAHWHLFPRR
                     AGDMKSHGLNGRGPVWWVPWEEMAAEDCQVQSPELEEMIKILSHELEKYLA"
     gene            complement(4101..5138)
                     /locus_tag="VXF95_001022"
     CDS             complement(4101..5138)
                     /locus_tag="VXF95_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HEV1081588.1"
                     /translation="MNQTVEYIKELTAIASPTGFTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQKNEEHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVTSTGKTVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDEKVTNEKETRALGIEVG
                     DFISFDPRTVVTETGFIKSRHLDDKVSAAILLNLLRVYKEEGIDLPMTTHFAFSVFEE
                     VGHGANSNIPEEVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLKSEAVS"
     gene            complement(5236..6561)
                     /gene="brnQ"
                     /locus_tag="VXF95_001023"
     CDS             complement(5236..6561)
                     /gene="brnQ"
                     /locus_tag="VXF95_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HEV1081589.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAVYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVVGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(6733..6825)
                     /locus_tag="VXF95_001024"
     CDS             complement(6733..6825)
                     /locus_tag="VXF95_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1081590.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(6868..7020)
                     /locus_tag="VXF95_001025"
     CDS             complement(6868..7020)
                     /locus_tag="VXF95_001025"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HEV1081591.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLEGAHNLPLSQ
                     LADSYD"
     gene            complement(7180..7758)
                     /locus_tag="VXF95_001026"
     CDS             complement(7180..7758)
                     /locus_tag="VXF95_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HEV1081592.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(7812..9212)
                     /gene="pepV"
                     /locus_tag="VXF95_001027"
     CDS             complement(7812..9212)
                     /gene="pepV"
                     /locus_tag="VXF95_001027"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HEV1081593.1"
                     /translation="MIAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLTDLQAKLDAFVAEHKLRGELQEEAGQYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVASVSLSEHGHTPHYVPMEDPLV
                     QTLLNVYEKQTGLQGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(9225..9830)
                     /locus_tag="VXF95_001028"
     CDS             complement(9225..9830)
                     /locus_tag="VXF95_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HEV1081594.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            10001..10801
                     /locus_tag="VXF95_001029"
     CDS             10001..10801
                     /locus_tag="VXF95_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1081595.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(10983..11816)
                     /locus_tag="VXF95_001030"
     CDS             complement(10983..11816)
                     /locus_tag="VXF95_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HEV1081596.1"
                     /translation="MNHKIAILSDIHGNVTALEAVIADAKNQGVSEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLVENDTEKFDQLLDAETDVAVY
                     GHVHKQLLRYGSQGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELVNILFRKV
                     AYDYEAELEFAKSKGLPFIEMYEELRREDNYQRHNLELLASLIEKHRYVEDVKNFFDF
                     L"
     gene            complement(11806..13650)
                     /gene="uvrC"
                     /locus_tag="VXF95_001031"
     CDS             complement(11806..13650)
                     /gene="uvrC"
                     /locus_tag="VXF95_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HEV1081597.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDNKIIDELKGKMAAAAQTMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMKHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNKP"
     gene            complement(13690..14391)
                     /locus_tag="VXF95_001032"
     CDS             complement(13690..14391)
                     /locus_tag="VXF95_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HEV1081598.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWPQVSARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(14470..15702)
                     /gene="murN"
                     /locus_tag="VXF95_001033"
     CDS             complement(14470..15702)
                     /gene="murN"
                     /locus_tag="VXF95_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HEV1081599.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(15707..16927)
                     /gene="murM"
                     /locus_tag="VXF95_001034"
     CDS             complement(15707..16927)
                     /gene="murM"
                     /locus_tag="VXF95_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HEV1081600.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFAIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(17039..17818)
                     /locus_tag="VXF95_001035"
     CDS             complement(17039..17818)
                     /locus_tag="VXF95_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HEV1081601.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQDFSPESQNLG
                     TPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(17887..19548)
                     /locus_tag="VXF95_001036"
     CDS             complement(17887..19548)
                     /locus_tag="VXF95_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1081602.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPERIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILRESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(19723..21945)
                     /gene="recJ"
                     /locus_tag="VXF95_001037"
     CDS             complement(19723..21945)
                     /gene="recJ"
                     /locus_tag="VXF95_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HEV1081603.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIGANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAVVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYRFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            22222..22980
                     /locus_tag="VXF95_001038"
     CDS             22222..22980
                     /locus_tag="VXF95_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1081604.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYTHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAMLSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     VDMTDVDNFFDNPSEPRAQQFLSKIINHESDKVK"
     gene            22991..23784
                     /locus_tag="VXF95_001039"
                     /pseudo
     CDS             22991..23784
                     /locus_tag="VXF95_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
     gene            23797..24474
                     /locus_tag="VXF95_001040"
     CDS             23797..24474
                     /locus_tag="VXF95_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1081605.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQV
                     NKKAYSL"
     gene            24484..25143
                     /locus_tag="VXF95_001041"
     CDS             24484..25143
                     /locus_tag="VXF95_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1081606.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISNLSHMLAKRWQQAA
                     E"
     gene            25287..26477
                     /locus_tag="VXF95_001042"
     CDS             25287..26477
                     /locus_tag="VXF95_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HEV1081607.1"
                     /translation="MKSIKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSLTFIL
                     ATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNLAIYI
                     FASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFLVGSY
                     ALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQFAFLK
                     IFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTKNIYDNLQAGSKVTLDRAYGHMII
                     EEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYSFRGDENAVYLDLLRNYAQKN
                     PNFELHLIDSTKDGYLNFEQKEVPEHATVYMCGPISMMKALAKQIKKQNPKTELIYEG
                     FKFK"
     gene            complement(26798..27679)
                     /locus_tag="VXF95_001043"
     CDS             complement(26798..27679)
                     /locus_tag="VXF95_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HEV1081608.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(27820..29148)
                     /gene="vncS"
                     /locus_tag="VXF95_001044"
     CDS             complement(27820..29148)
                     /gene="vncS"
                     /locus_tag="VXF95_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HEV1081609.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKDRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTKNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(29145..29801)
                     /gene="vncR"
                     /locus_tag="VXF95_001045"
     CDS             complement(29145..29801)
                     /gene="vncR"
                     /locus_tag="VXF95_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HEV1081610.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCIFTVRNVGYKLERK
                     "
     gene            complement(29850..29933)
                     /gene="pep27"
                     /locus_tag="VXF95_001046"
     CDS             complement(29850..29933)
                     /gene="pep27"
                     /locus_tag="VXF95_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HEV1081611.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(30113..31492)
                     /gene="vex3"
                     /locus_tag="VXF95_001047"
     CDS             complement(30113..31492)
                     /gene="vex3"
                     /locus_tag="VXF95_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HEV1081612.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(31544..32191)
                     /gene="vex2"
                     /locus_tag="VXF95_001048"
     CDS             complement(31544..32191)
                     /gene="vex2"
                     /locus_tag="VXF95_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HEV1081613.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQIDYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIR
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(32204..33481)
                     /locus_tag="VXF95_001049"
     CDS             complement(32204..33481)
                     /locus_tag="VXF95_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081614.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         9540 a         7641 c         6233 g        10139 t
ORIGIN      
        1 ttttagattc agtctactat acataaacta acctcctcat tattagcaag gattctactg
       61 attataacct aattcttaga ctacttcaag actaactgtc caataataat ctacagataa
      121 atcatccact cttaataaaa ttttattcaa tccatctact cattcccaaa aggttgctgt
      181 ataatgcaag acatttttct tactgatttt acttttcctt accctcaatt tagtgagcta
      241 ataaattatt cttcttcaaa aggttgagat ttatctagta actctaaaac attaatggta
      301 ggtagcaaca ttgcttcact gctatcaatt gccgaaacta ttgaaacaat agaacgtaaa
      361 taatgataaa gaatagcagt accatttacg tatagaatat cggtgatatt ttcatctata
      421 tttatttcaa aatatcctat tacagttaca gatatttttt tcatggcatc tttgtcaact
      481 aaagaaacac taagttttac ggctccatga ctataatcat ctgtatgacc aaccttaact
      541 atgggatata atatatcgaa ggtaaatgtg aacaaactga ttaggaaatt taaaccaact
      601 tctaacaatg tgttatactc aatgaaaacc aaagagcaaa ctaggaaact agcctcaggt
      661 tgctcaaaac actgttttga ggttgtagat ggaactgacg tagtcagctc aaaacactgt
      721 tttgaggttg tggatagaac tgacgaagtc agtaaccata cgcacggcaa ggcgacgttg
      781 acgtggtttg aagagatttt cgaagagtat tagaaagctc gatggactat tccagattca
      841 ttccactaga tttcgaaatc gagtagggga taatctctag cccctctcac accaccgtac
      901 gtgccgttcg gcatacggcg gttcaactaa ctgttaacgc atgtcattca aggtaataat
      961 ccaaacacga aaccaatcca cgtttttcaa ggactggttt tgatatagca cgtttaagta
     1021 ccgacttctg agatactaat tgatagtggt cgccccagcc agatacctta tccgctatat
     1081 aggccttatt atcacgttcc tgttcgtaga gccacgattt cgctatccct tcctctgacg
     1141 attcttattt ccagcgtcag acttaaaacg gtctatcccc agaccgtttt aatccgctac
     1201 ctcacgatag tcagacttgg gaatcgctat tgggttcacc ggtagtaggt gcccaccgag
     1261 gacttacacc tcaaatatat aataaaatga aataagaata ggacgaatcg ttcaggacag
     1321 tcaaatcaat ttctaacaat gttttagaag tagatgtgta ctattctagt ttcaatctac
     1381 tatacaacat gcccgtcgta catcaaaaaa agttgagaca tagcgtcttc aactttttta
     1441 cattacttta actactgatt aaagtgagtt tacgtcaact ttgataccaa caccttgagt
     1501 agttgtgata gtcaagtttg ttacgtaagt tcctttagct gtagctggtt ttgctttttg
     1561 gattgtttcg ttgaaagctt taaagttttc aaccaatttt tcagcttcaa atgatacttt
     1621 accgatgatt gcttgaacgt tacctgcacg gtcagcacgg taagtgattt taccaccttt
     1681 agactcttca actgctttag caacatccat tgttacagta ccagttttag ggtttggcat
     1741 caagttacgt ggtccaagga cacgtccaag acgtccaaca agagccatca tatcaggtgt
     1801 agcgataact acgtcgaagt ccaaccaacc gtcgttgatt ttagcaacaa ggtcatcttc
     1861 accaacaaag tctgcaccag cagcttttgc ttcttcagct tttgcaccac gtgcgaaaac
     1921 aagaacacgt gaagttttac cagtaccgtt tggcaatacc attgctccac ggatttgttg
     1981 gtcagctttt ttaacgtcga tgttcaagtt gtaagcaact tctacagttg cgtcaaattt
     2041 tgcaaagtta gtttcttttg caagtgctac agcttcttct acactgtatg cttttgtgct
     2101 gtcgattttc tcaagagcag cacgaagttg tttgcttttt ttagccattt tctattctcc
     2161 ttgtaagtgg ttcaatcgat tttcatctcc cacgtcactt ctcgaaatga tgaagtcttg
     2221 cgggttttca gtctactatt tttctcttcc tacggcctta agctcccttg ctgtacccaa
     2281 gtacaaggct cagtcacttg cctagtatga aaagcaacta atagactgct gtgagatttt
     2341 ctactgtgtt attgattagt caacaacagt gaatcccata gaacgagcag taccttcgat
     2401 catacgcatt gcagactcaa ggtttgcagc gttcaaatct ggcatcttag tttctgcaat
     2461 ttcttgtact tgcgcacgag taactgaagc aactttagtt ttgttaggtg tacctgatcc
     2521 tttttcaaca cctgcagctt ttttcaaaag aacagcagct ggtggtgtct tagtgatgaa
     2581 agtaaatgat ttatcttcgt aaactgagat aacaactgga atgatcatac cagcttgatc
     2641 agctgtacga gcgttgaact cttttgtgaa tcccatgatg ttgataccag cttgaccaag
     2701 agcaggtcca accggtggag ctggtgtagc tttaccagca gggatttgca attttacaag
     2761 tttttcgact tttttagcca tttctaaatc ctcctttgtg gttttggcgg taatgtaaga
     2821 tttttacctc ccacaagtat gctttacaca tacctttcca ttatacacta tttatctaaa
     2881 aatgcaagag aaaactttca tttttaatcg acataatcgc cgccttcaaa gccatagtac
     2941 tcttccaaac tgagaccact tgcagcaatt tctttggctt cttttccaac gtagcggaga
     3001 tgccattctt ctgccatgta gccagtctcc ttttccttgc ctttaagata gcgaacaaca
     3061 aagccatagt cagccgcatg gtccaagagc cactgggctg ccttttcttc agtaactaaa
     3121 tccccatctg tcccaatcaa atcaaaagca agacccgtct ggtgttcact gtaacctggg
     3181 cgtgctgagt agcgatctgc tgcttcctta ccatcttgat tgacatagtc ttggtagagc
     3241 ttagcctgag tttcataact cctaaaccca ctgtattggt cactgattgg atagccctca
     3301 gcctgcatag ctgcgattag tttgagcaac tctgccttgg ctgttggatt ttctcctgga
     3361 ttgtaatctt ttgacaaagg ataacgttta ttagctagga taatctcatc gtatttccct
     3421 tggatactat aatagctccc tttattgcta acttctgcct ttttctgact agaagcttga
     3481 gatttgctac ctacagttcc ttccggttga ctgctttgct ccgttttttg agtgttttct
     3541 tcaactttgg ttttttcttg cgaacaagct gcaagggtca atgctagtaa accagataaa
     3601 atgacatatc tttttttcat ttctttcttc ctctctctta ggccaaatac ttctccaatt
     3661 catgagataa gattttaatc atctcttcca gctctggcga ttgtacttgg caatcttctg
     3721 ccgccatttc ttcccagggc acccaccaga ctgggccacg gccattcaaa ccgtgactct
     3781 tcatatcacc tgctcttcgg ggaaaaagat gccaatgagc gtgggcatcg ccatttccta
     3841 ggagttcaat attcatcttt tcagcctcaa atgctttggc gactgcttct tggactaaac
     3901 tcatttcctc taaaaagcga agttttacag aagtttccat atgatggagt tctgtgacat
     3961 gatcttttgc taaaaataag gtatagccct taaagtattg gtggtcacca ataacaacat
     4021 agcctgtttc tagttctttt acaaagtagg gattttgccc agctttaatg agttcgattc
     4081 tctgacagat taagcacatt ctatgatacc gcctcgctct taagataagc atcaaccata
     4141 cgctcagtcg ctactactga atcgatgtgg gtgcgctcat aagagtgact ggactcaata
     4201 ccagctccaa gaagtgcatg cttgacctct gcacctgctg acatcgctgc tgaagcgtcc
     4261 gatccgtaaa atggatagat gtcgagctta aatggaatat cttgctcttt cgccaaagct
     4321 actaagtgtt gacggaagtc atagtgataa ggaccggaag catcctttac acagatagat
     4381 actgtgtact catccgtctg ttggtcatcg cccatagctc ccatatccac agccagatat
     4441 tctactacct cttctggaat attggagtta gcaccatggc ccacctcttc aaagactgaa
     4501 aaagcaaagt gtgtcgtcat cggcaagtca attccttctt ctttataaac tcgaaggaga
     4561 tttagcaaaa ttgctgcgct gaccttgtcg tccaaatgtc gagacttgat aaaaccagtc
     4621 tctgtcacga cagttcgcgg gtcaaagctg atgaagtcac caacctcaat acccaaggca
     4681 cgtgtttctt tttcattggt cactttttcg tctaaacgaa cttccatatt gtcctgagtg
     4741 cgttcagcag ttcctgcatc tttgtagaca tggcaagaag tctggtggat gaggatagtt
     4801 ccagataccg ttttacctgt actagtcaca tgaacggtac agttttcacc ctcaatcatg
     4861 ttccaaggaa aaccaccgat ccggtccaat ttgagacgac cgtcaggttt gacagcacga
     4921 acaatggctc cgagtgtgtc cacatgggca gttacatagc gatgttcttc gtttttttga
     4981 cctttgatgg tcacattgac accacccttg gctgtgcgaa ctggctggta accaaaacct
     5041 tctagagtct tgactaaata attcgaaatt tcacgagtga agcccgttgg cgatgcgatg
     5101 gctgtcagtt ctttgatata ttctactgtt tgattcattt cttcacctct ttcgctacct
     5161 attataacac atttatcatc ggataaaaaa agaaaatcac tcctgtagac ttggctacaa
     5221 aagtgattta agtgattatt ccatttcaaa aacatcgctt tcttgcttgt ttggtagaac
     5281 caatgagagc aagattccaa caatggctgg caccaaccat gggagagatg ccttggcaaa
     5341 aggaagaacg ctaacaagat ttgcaagaaa ctcaacctta aacgagcttc ctagtacgct
     5401 tgcaatggca ataactgtaa ccacagcaat tgtcaactgc atacctggtt ttgaaagggc
     5461 aacaaatttg ttgacaatga caatcataac gatagcaatc gtgattgggt acaagataac
     5521 cagtactgga attgagtact tgataatcgc atcaagaccc aaattggcaa tagcaaatcc
     5581 aatcaaggta aaggctgtcg cataaacctt gtagctgatt tgtgggaagc gctcattaaa
     5641 gaactcagct gttgacacaa tcaaaccaac agtcgttgtg aagcaggtta cggtaaccat
     5701 agctgcaagg aagagttgag ctgttgagcc aaagatttct tgagtggctt gtgacaagat
     5761 gtaaacacct ggtgttccac ccttcatcgc ttcagctggt actgggaaat gatttccaag
     5821 aaaacctaaa ccgatgtaaa gagcgctgaa ggcaagggca acaacgatac caacaaccca
     5881 aatagttgaa atgtattctt tcttacttga aaatccaagt tgtttcaagg tttgaactgc
     5941 gattacgcta aaggccactg aggcaagggc gtccaaggta ttgtaacctt ctaggaaacc
     6001 tgtaccaaag gcagaagctt gataagcagc tgaagcagct tgaggacttg ttccaccata
     6061 tttgatagct cccagaacga ccaagataac aatcaaaatt gcaaagactg gcgttaaaat
     6121 acgtccaatg cggtctaaga tttttgatgg attaagcgaa atcaaataga ctgccgcaaa
     6181 atacagaacc gtaaatacaa tcaagccaag tcctttattt gcatccgaca aaagggggct
     6241 aatccctact tcgtaagctg ttgtagcagt acgtggggta gcaaagaatg gaccgattga
     6301 caagtaaaga actgagaggt aaagagtcgc aaaccaaggc gctatcttcg ttgaaatctc
     6361 gtagatatat cctttaggat ttagcgttcc aataataagg gtcaagacgg cgataccaac
     6421 gcctgaaaag acaaaacctg cgatggcagg aagaaaatgt tctccagata gagcacctag
     6481 agaaggcgga aaaatcaagt tccccgcacc aaaaaatatt ccaaacagga gcaaacctgt
     6541 tagggtacct tttttagcca taaaaatctc cttcatattt ataaaatact gacctagtat
     6601 accacgatta ggagtctgaa aaaagcatca cgaggcaaat attaaatgtt ttcaattttc
     6661 ttaaaaataa gaattatcta aaaataaaaa ctctcctacc cagtccacac caagtaggag
     6721 aaatgcaaaa ttttaaagtt cttcaaaggc taacatgcca ccctggacat tgataacatt
     6781 ataaccttgt tctaacagga attggcaagc acgcgccgat ctcattccag atttgcaaat
     6841 aatataatgc aagcgatctt tgtccaatta atcataacta tcagccaatt gactaagcgg
     6901 taggttgtgg gcaccttcta aatgaagagc tgcaaactca tccacttctc tcacatccac
     6961 tagagaaagc tggtcgtttt ggtaaagctg gtaaaatgcg tcaaaggcta tttctttcat
     7021 tctttttctt ctaatactct tcgaaaatct cttcaaacca cgtcagcgtc gccttaccgt
     7081 gcgtatgtta ccgacttcgt cagttttatc tgcaacctca aagctgtact ttgagcagcc
     7141 tacgactagc ttcctagttt gctctttgat tttcattgac tataaaatgg ttttaattct
     7201 ttttttcaaa tctggcacta cttctgcctc aaaccaagga tttttggcca tccagatttg
     7261 atttcgtggt gatgggtgaa ctagcggaaa ataggctggc agatagtctt tatagtgttt
     7321 caccctctcc gttaccttcc cactgatttt ctcctgtaaa tagtaggctt gggcatattg
     7381 cccaatcaag agggttaact gaatatcagg caattcctgt aagagctgcg gatgccattt
     7441 ttctgcaaaa cctgtacgag gcggaagatc acccgacttg ccatgtcctg gaaagtagaa
     7501 atccataggc aaaacagcaa aataacctga attgtaaaag gtatcttcat ccacacctag
     7561 ccagtcccgc aagcggtcac cacttttatc tttccagtaa aggcctgctt cttgagtttt
     7621 aagtcccgga gcctgaccga tgatattgat gcgagcagtt tttggcgctg caaagagagg
     7681 ctcaatgcca cgctctgtat agctggcatt ctgtgaatcc gccatgatag cctgtttgat
     7741 tctttcgatt tgagacatct actttccctc caaaaagaag tccaagcata agatctcaga
     7801 cttctatcgt tttatttgat caattcgtaa atagcttcgg cataaattgc tgctgctcgg
     7861 aagagatcgt ccaaggcaat aaattcattg gcttggtgca tggtatcaat tgagtctggg
     7921 aacatagcac cataggcaac tccgcgctct aacaagcgac caaaggttcc accaccgatg
     7981 acttgttcat gaccttgtag gcctgtttgt ttttcataga cattcaacaa ggtttgcaca
     8041 agtggatctt ccattggcac atagtgaggg gtatgaccat gttctgatag actgacagaa
     8101 gcaactggca agttttctag gattgacttg atttgttctg gacttgttcc ttttggatag
     8161 cggatgttaa gggcaatggt attatcagca cttgtttcat cgaagcggaa gacgccggca
     8221 ttcatagaaa gagcacccat cttttcatcc acatgagcaa tcttgagatt ttcaccctca
     8281 tgatcgttca agagaatttt acctgcgatg tcaaggtagt ctttggctgg accagcaaag
     8341 ccaaactggc tgaggaagag ggcaaggtaa gttgcgccat tgacacctga agcaggcata
     8401 gcaccgtggg ctgatttacc aatgatcgtc accttgtatt ggccagcttc ttcttggagt
     8461 tctcctctaa gtttgtgttc tgcaacaaag gcatctagtt tagcttgcaa gtctgtcaag
     8521 tcacctgaaa cgactgctgt tgctgattct ggtaccatat tttcacgtaa accacctgta
     8581 aagctgtgaa gacgggctgc acctgtattt tcacctgcaa agtggaggta ttccgtgatg
     8641 tttccttttt caccattgat gattggaaat tcagcatctg gtgagaaacc aaagtctggc
     8701 ttggcgagtc ctacgtgctc gaagtagtag tccatatctg cccagcctga ttcttcgtct
     8761 gttccaacga tgaagcgaac tttcttagaa gttggaaggc ccaattcttt gatgattttc
     8821 aaaccatagt agcaagctgt tgtaggtccc ttgtcatctg aagcaccacg cgcataaagg
     8881 cgaccatctt tgatagttgg tgtgtaaggg tctgtgtccc aaccgctacc agctggaacc
     8941 acgtccatat gggcaaagat tccgagaact tcttctccat caccaaactc aaaatgtcct
     9001 gcatagttat caacattttt agttggataa ccatcacggt ctgcgatttc aaggaatttt
     9061 tccaaggctt ttactggacc aggtccaaat ggatgttggg catcagcctt gctatcatca
     9121 cgttctgagt tgatttccaa aaggctaaac aagtcagcca agaggtcttc tttgcgtttt
     9181 tctacttctg ctgtaaaatc aattgctatc attttttctt cttcctatct tttttcgatg
     9241 atttcatcta ctggcaagcg gtagcttggt tccaatttgt cgtctgtgta acccactgtg
     9301 atcaagagtt ctgggcggaa acggtcttca atttccaaaa cctcattgac ttttgatttg
     9361 tcaaaaccaa ggataatatt ggaaccaatt ccttggtctg taagagcgag aaccaagttc
     9421 atagcaacca aacctgcatt gagtgctagg tagtcgctga cttgttgttc attgtagcgt
     9481 gcaaattcag ctggcaaatt tttcatgaag tattgaagtt gttcttctga gaaattgtta
     9541 gcaccaccaa ctcgggcaat cttacgagcg cgtttggcaa ggtctgtatc tgtaaatagg
     9601 gcaatggtta caggtgctga tgatacctgc tcaaagtttg aaccataagc caactttgcc
     9661 agttcagcat ttttctcacg aacaactaca aatttccaag gctggctgtt gtgggcgctt
     9721 ggcgccaagg ttgcaatttc gatagccgta cgcacatctt ttggatcaac aggcttatca
     9781 gtgaaatgct tggtcgcatg acgtttttta tttaattcaa gaaatttcat aatcgatttc
     9841 cttttctaat tctactgctt ccattctacc ataatttgaa agagcttgca gggatttttc
     9901 atgattaagt ttttctatca cagacataaa agatatatat tggtttatca ggaaagtttc
     9961 tgataaacta gcaagtactt tacatttgaa tggagacagt atgaaaaaat ttagcctatt
    10021 actagctatc ctaccatttt tggttgcctg tgggaatcaa gctacaccca aagagactag
    10081 cgctcaaaag acaatcgtcc ttgctacagc tggcgacgtg ccaccatttg actacgaaga
    10141 taaaggcaat ctgacaggct tcgatatcga agttctaaag gcagtagatg aaaaactcag
    10201 cgactacgag attcaatttc aaagaaccgc ctgggaaagt atcttcccag gacttgattc
    10261 tggtcactat caggctgcgg ccaataactt gagttacaca aaagagcgtg ctgaaaaata
    10321 cctttactcg cttccaattt ccaacaatcc cctcgtcctt gtcagcaaca agaaaaatcc
    10381 tttgacttct cttgaccaga tcgctggtaa aacaacacaa gaggataccg gaacttctaa
    10441 cgctcaattc atcaataact ggaatcagaa acacactgat aatcccgcta caattaattt
    10501 ttctggtgag gatattggta aacgaatcct agaccttgct aacggagagt ttgatttcct
    10561 agtttttgac aaggtatccg ttcaaaagat tatcaaggac cgtggtttag acctctcagt
    10621 cgttgattta ccttctgcag atagccccag caattatatc attttctcaa gcgaccaaaa
    10681 agagtttaaa gagcaatttg ataaagcgct caaagaactc tatcaagacg gaacccttga
    10741 aaaactcagc aatacctatc taggtggttc ttacctccca gatcaatctc agttacaata
    10801 acactcttcg aaaatctctt caaaccacgt cagctttatc tgcaacctca aagctgtgct
    10861 ttgagcaacc tacggctagc ttcctagttt gctctttgat tttcattgag tataagatat
    10921 actaaaagcg atgggatcag ccaatcgctt ttttagtttg cattggttat tttaggaaac
    10981 tcttacaaaa aatcaaaaaa attcttcaca tcctctacat acctatgctt ttctattaag
    11041 cttgctaata gttccagatt gtgcctctga tagttatctt cacgacgtag ttcttcatac
    11101 atttcgataa agggaagccc cttggatttg gcaaattcta actcagcctc gtaatcataa
    11161 gcgactttac gaaataggat atttaccaat tccccatctt caacctctat cacggcatac
    11221 tgggcacggt gattttttaa cgcctcccaa ttaaaatagg gcatgccaat cgaccctgga
    11281 ttgatgattt gttgcccttg actaccataa cgaagcaact gcttgtgaac atgaccataa
    11341 actgccacgt ccgtttccgc atctagcagt tggtcaaatt tctctgtatc attctcaact
    11401 agcaagtcac caccatagtt tttgtcaggt aaattatgag agatagaaaa gcgcaatccg
    11461 tcaatttctt tcttttccag caaaggcaag cttcgtagcc agacaatcgt tgcaggatcc
    11521 attcgctcca tcaaatactg tgtcatacgc aagagctgaa cttcctgtgg gtcttctaag
    11581 ccatattgcc catctaaagc ctcaaggaca cgatcatccc aattgcctcg aacacttgct
    11641 gtgataggaa ggtcctttag cagggcgact aagtcatttg cgcctggacc aggaagaaaa
    11701 atatctccca gaagccagta ttcactgact ccttgatttt tagcatctgc aatcactgct
    11761 tctagcgccg tcacattgcc atgaatatct gataaaattg cgattttatg gtttattgtg
    11821 gtttccttcc gtttggtaat ctactctttc ttctgctact tgaggcaagg cttctccctg
    11881 cgggttcaac tttctttgca cagcctctgc aacgactcta ggtaccccaa cttcgacaat
    11941 ctcatccaca ctggcttcct tgattttggt caaagacttg aaatgcttca taagattttg
    12001 cttgcgttta ggtcccagac catcaatccc atccaattga gatgagaaag aatttttgga
    12061 gcgcagttgg cggtggaagg tgatggcaaa gcggtgcacc tcatcttgga tgcgttggag
    12121 gaggaaaaat tcctgagaat tgcgagacaa gtccaccact tccagcggat ctccaaagag
    12181 caattcatgg gtttggtgct tatcattctt ttgcagacct gcaattggaa tatccaagcc
    12241 cagttcttct tggatgactt gcttagcaat attgacttga ccttgccccc catcaatcac
    12301 aatcaaatct ggaggagtca aagcctcacg ctgtactcga ccatagcgtc tgcgaatgac
    12361 ctctcgcata ctggcatagt cgtctggccc gactacggtc ttgattttat acttacggta
    12421 atccttctta ctaggcttgc cgttgacaaa gaccaccatg gctgaaacag gactagttcc
    12481 catgatgttg gagttatcga aggactcgat gcgaactggg gttgggattt gaagcaagcg
    12541 tcctaaattt tcaatagctc cttgggtctt ctcgacagat ttctctagca ggttgaactt
    12601 ctgctctagg ctaacacggg cattttttat agctaaattg accagctgct ttttctctcc
    12661 acgttgaggc ttaagaatct tggaatccac caaggccttg acagcctctt cgtcaatatc
    12721 ctgcggaatc agtacctcat tgggaactag gtgagatttt tcttgataga attgtcccac
    12781 ataggtcaag aaatcctcat ctggatcatt gaagtagggg aagagattga catcgcgctc
    12841 gatgagcttg ccctgacgaa caaagaaaac ctgcacacac atccagccct tatccacata
    12901 gtagccaaag acatcgcgat tttggagatc cttagccatg acccgttgct tggttcgaag
    12961 cgttccaata gcctgaatca ggtcacggta ttccgccgca cgttcaaact ccatagtctg
    13021 ggctgccgct gccattttgc cctttagctc atcaatgatt ttgttatcct gccctttcag
    13081 aaaatcagaa acctcctggg ccatagactt gaaataagcc tcatccttct tacagatggt
    13141 gtgagccata cactggccga tatggtaata aaaacagacc ttagagggcg ggttggtaca
    13201 cttacgaaaa gggaatatcc gatccagcaa ccgcttgatt tcattggctg cccccacatc
    13261 gggataaggt ccaaaataaa gacctccgtc ctttttgacc tgacgagtga taatcaagcg
    13321 tggatagcgc tcattggtga ttttgatgaa aggataggac ttgtcatcct tgagcatgat
    13381 attgtacttg ggcttgtttt ccttgatcag gttgatttct aggagaagtg cctcaatatt
    13441 agactccgta acaataaatt caaaatccac aatttcagac accagagcct ctgtcttggt
    13501 atcatgactt ccacgaaaat aggaccgtac tcgattacgc agatttttag cctttcctac
    13561 atagataatg gtgccatttt tatccttatg aatgtagcaa ccagggctgg tcggcaagag
    13621 ctctagtttt gatttaatca agttgttcat agttccatta tagcaaaaaa agtagggaaa
    13681 gatagtaccc tactcactag tctcatatat ttttcggagg tttgcaacat cctcttcctg
    13741 gataccataa aaggaacctg ctggttgcat gacagacttc tcatctgtat ggtccaagcc
    13801 aatcgcatga cctaactcat gttctgccgt atggacaagg cgttcatagg agtagccata
    13861 gtatggattg gacaaataat aatgattcaa ccgcaccgtt acggacaaga attgccctgt
    13921 taagagatta gtttgacttt ccgcctctcc tgccacagga gtgcctccgt cgttcatctc
    13981 cgtagccgta atatccgcct tactagactc agtcacgagt tcaaagttaa aagcaccagt
    14041 ttgattccag ttctggattg cttctaaata agcctcttga aagcgtgaat ccatctgcgg
    14101 atccaggtaa atacgagcag agacctgtgg ccaccttcct tcagaatgct ggtgactatc
    14161 tgtctggctt aacttaggca gttgccctgt tttctcccat tggtcaatac tttgttgacc
    14221 aatttttact gaccgttctg cttgctttag cgctccttga aaatccccgt tcagatacca
    14281 gagaagtccg aaagcaagca cacataagag cacaactatc caaaccagac gccaaaacaa
    14341 acgccacaca aaagaaaaga aagcccctat caaacgaaaa agccagcgca tgtctctcca
    14401 cctttctagc aaataaaaat tattttacta aaagaagcta aaagaaatct aaatactgac
    14461 tttttcatct taacgtccta ctattttttt gagtaactgg atagctttgt attttaaagg
    14521 cgatggatgg taacggaaag tacctgcttt gcgtacaata tagccattaa aattctgttt
    14581 aaaacgcaaa acaccatcac ttccatcaaa aatcccttga atgcctagga agttgtattt
    14641 aggtattcca cgttttatgc tttccaacat aacatatttt tgaagcagtg caggggcata
    14701 gaacttatta aactcagtgt aggaaccact aaagagataa gtcgtttcct gaggcatata
    14761 aacaaataaa ctcccagcta aaacaatatc ttcttctcca tatttttcaa tcaagtctcg
    14821 cgcttctgct tttcgaactt caaacgtttc aaattgacta gaatattctc tcagttgatt
    14881 ttgttttttc tcagaatgag gatttttact caaatcaagt cgcaacttgt ccaagttttc
    14941 ttctagttta ctttgttcac cttgcaattt gctcatatag tccgaaaaat tcaagcttgc
    15001 tatgagaaac tccgcttgtt ctccaaaagt atcataaaaa tgctcataat attctaaact
    15061 tttatcacta tattctctac gttcagaggt ttcttttgtt atattcttaa aaatcgatag
    15121 ttcttcacgt tttaactttt tcaaccgaat gccaaaggtt tcagcctttt tcaccaaggg
    15181 tttacccttt ttgctaaaac ttttaagcaa actcttttca gttaattcag ttaaatcttt
    15241 atagtataac caatctggtt ctccacctgg gtaacctgtt gttaagccat caaattgata
    15301 acctaaatca gtcaaacctt gaataatact ttttttctca gcatctattg gattaccttg
    15361 gctatcaaaa gtttgataag tttcataagg ttttacaagc aactctaata caccattttg
    15421 cttggcatat tcttttaact ctgcataaaa aactggaaga gcatcttgtt gggtataaat
    15481 cggccccgaa ttgagttcca tatgcagacc acccagcatg ggcaagctat aaaccagagc
    15541 tgcaacttga atttctcctt cttgtttcaa agcaagataa acaattcgag cccctctttt
    15601 ttctagcaaa tcccccatct ggacagattg cataaaggaa cgagaagaaa cctgatcaga
    15661 ataagtctga aactcttctt tcgtgagtgt tgttagtgcc atatacttac tttctatgtt
    15721 tttttcttaa tgttttacgg aaatcaagag caagtcttaa cagaggatag agaggatgag
    15781 tgggcattgt aaattcaccc aagtattctt caatcgttgg attaaatttt tccttaaaat
    15841 gataaagtcc accattgaga gagttttcaa caccacctaa attttgccag accatacctc
    15901 gctcaaaggc atagcgagcc gtttcatacc atgttaaaat tggtgcattg taacgtttaa
    15961 aatcatcatc cataccagca tatatattga cagaggtagt accaaattcc aaactcaaag
    16021 tagccgctaa aggaactctc gcttgaccta catctatata ttcctgcaag aaggtcaatt
    16081 cctctaacaa acgttctttt tccttcttct gcgcttctac ttttgaaatt cgagtcgact
    16141 cagtaaaggt ctcttccaag gctctatttt tcgctaactg ttcttctaac tcttgcgaac
    16201 gtttagaaac atccaaggtg gccaaggtga tataggcctt gtccttaaaa ttatctaaca
    16261 attttttata ataggcttca ttcctcaaat gaatctcttt tcgcttctca gtttttttca
    16321 tcaactccga aaatgaatct aatagttcca gtccaccata ttgaatctca agccctttgt
    16381 ttcgtgctgt tcgaatagcc tgttttgttg acttggaaag tttatcttct tcaaaatttt
    16441 ccttgtatat tttcgcctga atacgaggtt gaatggtgtc tcccatttcc tccgtttttc
    16501 ctgaccacct tactcccatt tgttgcaaac tatcaataat agccagattt tcaggaaatt
    16561 ctgtcttttc ctgattgatt aaactttgag ataggcaaat acttgggtca aaagtcacaa
    16621 aaaccgctct cttactgcga gcataggact taatagactg aatggcaaaa ttcaagagtt
    16681 ctttatcccc ataatccaat ataggtcctc ttgggatgta aaacatttta tagcctagcg
    16741 gaagagttct aatcaaaata ctagctgtcg ccagtaattt ttcttccctg taaacaccaa
    16801 acttctcatg ttgccaatta gacttaactt cctcccaagc actactttgt aatacattgg
    16861 ctaattcatg ttctttgaca aactgatcat attctaatgt gggaatgcca atttgataac
    16921 ggtacatttc ctactctctt tcctccagta ttttattact attctactac tttcgtttga
    16981 aaagtctagt gaaaacatat tttattttag ttctacttcc cctatgctga agttcaaact
    17041 aagtcagtct ctcttctaat ttgaaatcaa ttggtagggt tgttaaaaaa acttccaatt
    17101 gtttttccca gtagtaccac tcgtgagttc cagcgctatg gctataggtc acatcaaaac
    17161 ctagtttttt gagatttttc actgcaagat tattggcttc gtacaagaaa tcctgttcgc
    17221 cacaccacgc ccaaagtttg gtctttttat ccgatttttt agccagactt tcaagagaat
    17281 agggactagt tgtccagtct ttaatctctc caaaaacacc tctccagtag gctggcgttc
    17341 ccagattttg actctcagga gaaaaatctt gaaagctcaa tgcacctgaa aagctagctg
    17401 catgagaaaa acgatttgtc gcaagagcca gtttgaaaca gccgtagcct cccatagaaa
    17461 gaccagcgat aaaggtcttt tcacgcttgc tagtcatatt agggaagaag cgtttcagaa
    17521 cctgtggcaa ttcctctgct agagccgtgt agtagtcaaa accatactgg gtatcggtgt
    17581 accaaccatt gctggtattg ggcataacaa cgatgagatt agttcctcga agcaagcgtt
    17641 ctacattggt ccgcttaagc caactattat gattgccaga catcccgtgc aaaaggtaca
    17701 agacgggaat atcttcacac tctggttctt ccactcgatt ggcatcaggg tagaggacat
    17761 tcacccccca ctccatatcc aatacttgtg agtaatactc gattttcatt actgccatga
    17821 ttttctcctt ctatttttct ataagaaaaa gccgaaactc gactttctct ctgtttattt
    17881 taacgattat tttgcttcca tgactactgg taaaatggct gggcgacgct tggtttggtc
    17941 aaagagatac ttggtcaaat tatctcgaac cttcccttta agatctgccc agtcaaagtc
    18001 atctccttga agatactctt ctaccgtttg gttaatcaat tctgaacttt cacggagaat
    18061 atcgcgactc ttcttgagat aaacaaatcc acgcgtgtga acacgagccc tagccacaat
    18121 tttcttctca cgacggttga ctgtaatagc cacgatgaaa attccatcct ctgacaagac
    18181 cttacggtca cgaagaacaa catttccaac atcaccaatg gcattcccat caatcaagat
    18241 atctcctgct gaaaccgatc cagctggaac aaagtctcca ttctcgtaag ccatggtcgt
    18301 ccccttttta ggaatgaaga tgcgttctgg caacatccca actgccatgg cagccttagc
    18361 gtgagcatcc aactcacgat actccccttg gacagggaag aggtacttag gttgcaaaag
    18421 attgatcatc agctgcaaat cacgcacatt tccgtgccct gatacatgta aactttgggt
    18481 aatcaatttg acaaccccac ctgcctgata aatcatattt tccacacgcg caacaaaggc
    18541 ttctttagca atagacggag ccgtagcaat atagaccagg tccccatcct tgatttctac
    18601 ataacgatgg cgaccaatcg acatcttacg aagtccattg ataggttcac ccatacgacc
    18661 tgtctcaaga ataatcaact catggtcttc aaatcgagac atatctttag gcttaatcaa
    18721 gagaatttcg ttggctaaag acaacttctt aagacgaatc gctgtgcgga cgatattttc
    18781 aatatcaaat cctgtcaaga cgatacgtcg acctgtttta tccgcagcgt caaaaatctg
    18841 ctgaatacga gaaagattac tggaaacagc tgcaacgatg atacgacctt cccagtcagc
    18901 aatagtttgg gtaatttcat ccctaacttc actttcacta gccacctgaa tattgctgtc
    18961 tgcattggcc gaatcactga ggagagccag gacgccgtca cgaccaatct ctgccaaacg
    19021 agcaaaatca gttgcataag attcactagc cgtttggtca aatttgaagt cacctgtata
    19081 aacgatgctt ccttccgatg tcttcaagac aattcccaga ctctctggaa cggagtaagt
    19141 cgtagggaag aaggaaacca ctgtcccacc aaaatcaatc tccgtattct catcaatgac
    19201 atggaaatca ttaaatttct taacggcatc atttcctttg acaaagagct ttgccaactc
    19261 aatggtcaac tcagacccaa atacaggaac tttagcctct gccaagagat acggtagagc
    19321 accaatggca tccgcatgcc cgtgggtcaa gaaaacccca gcaatacggt cgctattttc
    19381 aaaaaggtaa tccatgtttg gaatcaccac atcgacccct aattgttcat tttcaggata
    19441 ttttaaccct acattcaaaa caaaaatgga ctctccaatt tcagcaatgt acatattttt
    19501 tccattctca cgcacaccac caagtgttgt taaactgata ttactcattt ttcctccaaa
    19561 atcttagttt atcttgatta tagggcaatt ctaccctctt attctaaaag ttctgatact
    19621 ttcagccgaa tcttttccta ccattatacc atttttttga tgattttcaa aatgaaggtc
    19681 tgttttcaaa aaagagttga tttcccaact ctttcctaac ttctactctt tttccatcaa
    19741 aaaatcataa atttcttgca ccgtacccag cgccatcatt tcttggtctt taacggtttg
    19801 tttgagattt tggtaaattt gactttctcc tatctcccgc tttggcgcct ctttattgac
    19861 tgtcatcaca ccatctttta tcgtcacaaa gcctagttct tcaaatactt gaatcatctt
    19921 gaccagcaag atttgttgaa tattaagata tgcagccaaa tctttcagct tgtagcgaat
    19981 atcaaactct gggaaccggt aaatagtctt gtacaatttg gcaaactgat ctctagtccc
    20041 ataacctgtc agataataag ccttgtcaat atcatttttg aaatagacag cagagaaatg
    20101 ctgttcctga aaaatggtct tcagctgagt aatatcctct ggaatgtttt ttacgacaac
    20161 agcttcacta gccgcaagat ttggcagttc tccaggaaaa tccaagactg gaacaccttc
    20221 tggcaagact gcattttttc cacgaatgtt aaaaagttga acaccttcca ctcgcgcatc
    20281 caccatcatc aactggaggg cagtttggcc attccattgg ttgacagaca atttaaccgc
    20341 taactctaga ttcttggttt gagaaaactc tgtcgcccat ctgccttgac caaaggctac
    20401 cacttcaaaa ctcgcctcac ccttggaaat tttcagcttt agatgggcat tacctgcccc
    20461 catagtacga gcactttcga cctgaaaatt cttgatataa aaaataggtt tctgattatc
    20521 cattccaaaa ggagctaaac gttcaaaact tttgaccgtt tccaagctaa gtgcctccaa
    20581 atccaactct tcatctaggt ttaacttatt cttgccacca gcatctgcac ctttttcacg
    20641 aacataatct tccaaaacct gagataaatc tgagagttgc tcaacttcca acgtcatacc
    20701 cgctgcacct gcatgacctc caaaggcgat gaagaggtct cgatggggat ccagagcttc
    20761 aaaaatatcg accgcttcca cactacgagc actgcccttg gcacgaccgt cttctatatt
    20821 aagaacaatg actgtctgtc ccaattcttc caataaacga ccagccacga ttcctagaac
    20881 cccaggattc cagccttcct tggccaagac ctgaaccttc ttctcaggat ccaccatggt
    20941 cttggcttct tcatagatag actgaacgat ttccttgcgc tcttcgtttt tctggtgaat
    21001 cataagggca atctcatgcg cttcctcatc atcaaatcca gtcaacaaat caatggcagg
    21061 attgggatca tccaagcgac ccaaggcatt caaacgagga gcaatctgga aaccaaccgt
    21121 ttcttctgtt acttcgttgg caccaatccc agccatgtcc agcatttctt gcagaccaat
    21181 gcgctgggta tgacccaaca tttccagacc atattgaact aagatacgat tttcatccgt
    21241 cagactcacc atatctgcaa tagttccaat agcgaccaaa tcaagcaatt ccacttgcac
    21301 ttcttctaac agggcacaag ccaacttgaa agcaactcca caaccagcca aatatttaaa
    21361 aggataatcc gcatctggat gttcaggatg gacaatagca taagcatctg gcagggtttc
    21421 aggcatggaa tgatggtctg tgacaatgac atctactccc atagactgag ccaatgcaat
    21481 agcctcatga ccagcaaccc cattgtccac cgtcacaatc aaggaaatcc cttcttgctc
    21541 gataaagtat ttataaacac tagcattagg gccatagcca tcggtaaaac gatttggcag
    21601 gtaaactcgg cactcagcac caagttgttc caaactttcc ttcacaatag aagccgaagt
    21661 catgccatcc gcatcatagt ctccataaac gagaatattt tccccttctt caatagcctg
    21721 acgaatccgc tccactgcct tgtccatatc atggagcaga taagcatcat gtaagtcctc
    21781 caaggaaggt tctaaaaact tcttcagact ttcttggtcc tgaatccctc tctcaaacaa
    21841 taaccgagcc acctcaggac ccagtccagc cttcttggct atctttgtaa aatccgcatc
    21901 ttctacctgc agggcaaact gccattcata agtaggtgtt atcaaaaaga catccactct
    21961 ttctaagaat tctattgctt cattataaca tgatttagac gttttctcta tccagattgc
    22021 ttttttataa cattttatag tatattgaaa ctagaatagt acacctctac ttctaaaata
    22081 ttgttagaaa tcgatttgac tgtcccgatc gatttgtcct gttcttattt caatatagtg
    22141 aattttttca gatatggttt gacaagaaca ttcttttatt gtagaatcgt gttataaaat
    22201 ctaacataaa ggagatctct catggcttta gtagaattta aaaacgtcga aaaatattac
    22261 ggagactacc acgcactccg caacatcaat ctccgttttg aaaaaggaca agttgttgtc
    22321 ctgcttggac cttctggctc tgggaagtcc actcttatcc gtacgatcaa tggtttagag
    22381 gctgttgaca aaggaagtct cctagtcaat gggcaccaag ttgctggtgc cagccagaaa
    22441 gatttggtac ctcttcgcaa ggaagtcggc atggtttttc aacattttaa cctttataca
    22501 cacaaaactg tgttagaaaa cgtgacactt gcgcccatta aagttctagg aattgataaa
    22561 aaagaagctg aaaaaaccgc ccaaaaatat ctggaatttg taaatatgtg ggacaagaaa
    22621 gattcctatc ccgccatgct atctggtgga caaaaacagc ggatcgccat cgctcgtggt
    22681 cttgctatgc atccggaact cctcctcttt gatgaaccaa catctgctct tgatcctgag
    22741 actatcggag atgttctagc agttatgcag aaactggcgc atgatgggat gaacatgatc
    22801 atcgttaccc acgaaatggg ctttgctcga gaggttgcgg accgcattat ctttatggcc
    22861 gacggagaag ttttagtaga tatgacagat gtcgataact tttttgacaa tccaagcgaa
    22921 cctcgtgccc aacaattcct cagcaaaatt atcaaccacg aaagtgacaa agtcaaataa
    22981 ggaggcgcct atgaaaaaaa aattcttttt atcagcatta ttgattagcc ttttcggcct
    23041 tgctgctgcc aaaccagtcc aggctgatac tagtatcgca gacattcaaa aaagaggcga
    23101 actggttgtc ggtgtcaaac aagacgttcc caattttggt tacaaagatc ccaagaccgg
    23161 tacttattct ggtatcgaaa ccgacttggc caagatggta gctgatgaac tcaaggtcaa
    23221 gattcgctat gtgccggtta cagcacaaac ccgcgccccc ttctagacaa tgaacaggtc
    23281 gatatggata tcgcgacctt taccatcacg gacgaacgca aaaaactcta caactttacc
    23341 agtccctact acacagacgc ttctggattt ttggtcaata aatctgccaa aatcaaaaag
    23401 attgaggacc taaacggcaa aaccatcgga gtcgcccaag gttctatcac ccaacgccta
    23461 attactgaac tgggtaaaaa gaaaggtctg aagtttaaat tcgtcgaact tggttcctac
    23521 ccagaattga ttacttccct gcacgctcat cgtatcgatg ccttttccgt tgaccgctct
    23581 attctatctg gctacactaa taaacggaca gcactactag atgatagttt caagccatct
    23641 gactacggta ttgttaccaa gaaatcaaat acagagctca acgactatct tgataacttg
    23701 gttactaaat ggagcaagga tggtagtttg cagaaacttt atgaccgtta caagctcaaa
    23761 ccatctagtc ataccgcaga ttaaggagga taccctatga cagatttatc atcttggaca
    23821 gcctattttc aggattttgg acaatttttc aatggtttcc tcttcaccct tgccctagcg
    23881 attggatcct ttatcctcgc catggtctta ggaatcttct ttggtgccat gtcaaccagt
    23941 aaacgtccaa ttttacgcat tttagctcgc atcttcgtgg aattttacca aaacactccc
    24001 ctcttggtgc agtttgttat tgttttttat ggcctacctc ttatcagtga ccatatcatc
    24061 atgattccaa tttattggac agccgttctc tgcgtgggac tctatcacgg cgcttatatc
    24121 gctgaggtta ttcgttcagg gattcagtct attcctagtg gtcagatgga ggccgccttg
    24181 tcgcaaggtt ttacctatat cagtgccatg cgcttgatta tcttgcctca ggccttccgc
    24241 atcattctcc ctccattgac caaccaaatt gttaacctca tcaagaacac atctactgta
    24301 gctatcatct ctggagtaga cttgatgttt gtgactaagt cttggtcggc tctcaacgga
    24361 aactatatcc cagccttttt aggtgctgct cttctctact ttgccctatg cttccctgtt
    24421 gcccagtttg gtcgcaagat ggagcaagtc aataaaaaag cctattcact ttaggaggtt
    24481 actatggaat ctattttaga aattttaacc ccagataacc tagtctttat ctttaaagga
    24541 tttggcttga ccctctatat ttctctgatt gccatcatcc tctctactat catcggtacc
    24601 gtgcttgccg tcatgcgaaa tggaaaaaat cctatcttac gcattatttc cagtatttat
    24661 atcgagtttg tgcgcaacgt tcccaacctt ctctggattt ttactatctt tttggtgttc
    24721 aaaatgaagt ccacaccagc aggtattaca gcctttactc tctttacatc agcagccttg
    24781 gctgagatta ttcgaggcgg tctcaatgcc gtagacaagg gacaatacga agcaggaatg
    24841 tcacaaggct tcacctcagc ccaaatcctc tactacatca ttctcccaca agccatccgc
    24901 aaaatgctac cagccatcat ttctcagttt gttaccgtga ttaaggatac cagtctcctc
    24961 tactctgtta tcgccctaca agaactcttt ggagccagcc aaattctcat gggccgttat
    25021 ttcgaaccag agcaggtctt cagtctttac atcctgattg ccctcatcta cttcagcttt
    25081 aacctagcaa tttctaacct gtctcatatg ctagcaaaac gttggcaaca agctgcagaa
    25141 taacaaatta gctctctagt tcattggaga gttttttgat gatagtagat atttatagac
    25201 ctcaatttga caccatacat tttctatgat aaaatgtaac aaatttattt acaacaaatc
    25261 gaaatctaaa tgaaatggaa ttttctatga aatcaatcaa aggactactc tttatcatag
    25321 ctagttttat cttgactctt ttgacttgga tgaacacttc tccccaattc atgattccag
    25381 gactagcttt aacaagccta tctctgactt ttatcctagc cactcgtctc ccactactag
    25441 aaagctggtt tcacggtttg gagaaggtct acaccgtcca caaattcaca gcctttctct
    25501 caatcatcct actaatcttt cataacttta gtatgggcgg tttgtggggc tctcgcttag
    25561 ctgctcagtt tggcaatctt gccatctata tctttgccag catcatcctt gtcgcctatt
    25621 taggcaaata catccaatac gaagcttggc gatggattca ccgcctggtt tacctagcct
    25681 atattttagg actctttcac atctacatga taatgggcaa tcgtctcctt acatttaatc
    25741 ttctaagttt tcttgttggt agctatgccc ttttaggctt actagctggt ttttatatca
    25801 tttttctata tcaaaagatt tccttcccct atctagggaa aattacccat ctcaaacgct
    25861 taaatcacga tactagagaa attcaaatcc atcttagcag acctttcaac tatcaatcag
    25921 gacaatttgc ctttctaaag attttccaag aaggctttga aagtgctccg catccctttt
    25981 ctatctcagg aggtcatggt caaactcttt actttactgt taaaaattca ggcgaccata
    26041 ccaagaatat ctatgataat cttcaagccg gcagcaaagt aaccctagac agagcttacg
    26101 gacacatgat catagaagaa ggacgagaaa atcaggtttg gattgctgga ggtattggga
    26161 ttaccccctt catctcttac atccgtgaac atcctatttt agataaacag gttcacttct
    26221 actatagctt ccgtggagat gaaaatgcag tctacctaga tttactccgt aactatgctc
    26281 agaaaaatcc taattttgaa ctccatctaa tcgacagtac gaaagacggc tatcttaatt
    26341 ttgaacaaaa agaagtgccc gaacatgcaa ccgtctatat gtgtggtcct atttctatga
    26401 tgaaggcact tgccaaacag attaagaaac aaaatccaaa aacagagctt atttacgaag
    26461 gattcaagtt caaataagta atcatactct cctgggattt cccaggagag ttttttatag
    26521 ccaaatgaaa taagaccgga acgatggaat tttggcattc aaatcaattg ataagaatat
    26581 tttatagtgg agtgaaatag gatacgaaca aattgattag gaaaatcaaa tgaatttata
    26641 gaaatctttt agcagttatg ttgtcctatt ctagtttcaa aacgctatgg aagcagcatt
    26701 gtgctagtct agattcagtt tactatacta aaacgagtag cttgaaatca aaaaacccac
    26761 cctcacaggc aggttttatc tgtattattc agctagatta tgctttacct tctgaaccga
    26821 atacgtcgat acgttcttca accgatgctt ggatagcttt tacaccgtca gccaagaatt
    26881 tacgtgggtc gaagagtttt ttcttgtcgt attctgcttc gtttgcttcg taatcacgag
    26941 caaatttacg agttgcgtta gcgaatgcga tttggcattc tgtgttaacg ttaactttgg
    27001 caacaccaag tttgatagct gcttggattt gctcatcagg aatacctgat ccaccgtgca
    27061 atacgattgg gaatcctgga agagcttctg tcaatttttg caagtggtca aggtcaagac
    27121 cttcccagtt tactgggtaa gggccgtgga tgttaccgat accagctgcc aagaagtcga
    27181 taccagtttc aaccattgct ttagcgtctt cgattggagc caattcacct ttaccgatga
    27241 ttccgtcttc ttcaccaccg atagtaccaa cttcagcttc tactgagata cctttagcgt
    27301 gtgctttttc aacaacttct ttagccaatt taaggttttc ttcaactgga aggtgtgaac
    27361 cgtcaaacat gattgaagta taaccaactt cgatacactc aagtgcatct tcgtagtgac
    27421 cgtggtcaag gtggatagct actggtacag tgatacccat tgattcaaca aggttagcga
    27481 tcaagttgcg agcaactttg taaccaccca tgtatttagc agcacccatt gaagtttgga
    27541 tcaaaactgg agctttttta gcttctgctg cgcgcaagat agcttgagtc cactcaaggt
    27601 tgtttgtgtt aaatccacca actgcataac cgttgtcacg ggctgcttgg acaaattttt
    27661 ctgctgaaac gattgccatt ttatcaggcc tcctgtatat ttttatgggt catcccattt
    27721 acattgttca ttttatcact ttttgccaaa aaaatctagt ttttcccgca gtttcgattg
    27781 attttcttct aactccatct atgtaaaccc tttctctccc tagtcttgga cgacttttgg
    27841 aaaatctata aagaaggtta aacgattctc ctccatctcg aaacgataag ctaatttttc
    27901 atgttctaat agactcttaa ccacaaaaag ccccatacca gaccccttga ccttgcgact
    27961 ggcattgtca gaaaaagact gggctagttt ttcttgttcc tctgagctac agctattttc
    28021 gataaaaagt tctccttctc tttctccaat tcgaactaag ccacctggaa cagagtgctt
    28081 aatggcattg ctgatgagat tagaaagaat caacttcata actgatgggt ttagataagc
    28141 ctgctgatgg gtcaaactat tgtctatctg gagctctctt tccttggcta gcaaggcata
    28201 atctttgacc agatttttcg tcatctggag gaggtcaatt gtttccctat catctcgcaa
    28261 ttcctgcaca gaagagaggg aaagtatctg cagaacatgg tgattgagtt catccacaat
    28321 ccccaaggca actcccagat actggtctct atccttataa cgaccgatat tctctctcat
    28381 attttcgatt aggattttca aactagccag cggtgttttc aattcatgag aagctcctcg
    28441 taggaattcg accttcatct tctccagctg gagaatggct tcattctttt catgcaagtc
    28501 cgcaataaca gtcaagagat gctggtagag gctattgatt tgttccttga gattacctat
    28561 ctcatcctta gaatccacgc gcaatcgcac ttgggaatcc aggtccatca tccgacgggt
    28621 cacccgcttg atttccaaaa tcggtgcaac aatagtccga gcgtagatgt aggccaccaa
    28681 gagggaaatc agaaaggagg ccagcaaggt atagggaaga aactggagac tgatttgctc
    28741 cgcttccttt tgtaaatcca tggaagctag aaactggaga atcatagtac caccgtcttg
    28801 cgttttcacc tcgcgctcct caataaagag agaggttgtc tggcggtctg tgtccagagg
    28861 aagactgtcc ttgacttcta acttgtcctc ggtcatctca cctttgacgg tccccttgat
    28921 atcactagtc tgggaataca agtctaacac ttgctcgata ctctgcctat ctttcccttc
    28981 tagggactgg gcaatggctg ttgccttttg accaatggtt tcctgacgat gactcagata
    29041 agtcgaagga aaaagaaaat aaatagctaa atgaaggcag ataaccagaa cactaaatat
    29101 cgagaaggta tagataaata tctttgtaaa taaacctgtt cgtttcattt tcgctccaat
    29161 ttataaccaa cattgcgcac agtgaagata caatccaagt ctagcttttt ccgcaattcc
    29221 ttgatataaa catcaataac acggtcaaag ggaacctcat ctgtcgcttt ccagacggca
    29281 tcgataatct gagaccgagt caaggcccgg ccttcatttt tcactagata gtccagaatt
    29341 tccaactctt tggcattgat aggcacttct tgacctgcga ggcttgcact gtagctttca
    29401 aagtccacct tggtatcctt gtaagaaaag attcgtcctg tatcgtagta gcgcttgaaa
    29461 atcgcgtcca ccctcacttt taagagggag agggagaaag gtttttccag atagccatct
    29521 gccaaagagg caaaggcact catcttgtat tcctcatcct gaaaagctgt caacatcaag
    29581 acaggaacct gactggtttt acgaatctca gctaggactt ctaagccgtt aagcttgggc
    29641 atctggatat ccagtaaaac cagggccacc tcatagctag aaaattgctc cagagcttcc
    29701 tgaccgtccg ctgcctcaat agtttcatag ccacaatccg tcaaataatc actgaccccc
    29761 tcacggatca tctcttcatc ttctacaatt aaaattttca tactttaact gctctctatt
    29821 ttttattttt cttagaataa atacctactc tattttctat tatagtctct tgctggcctt
    29881 ttgtctgtaa gcaactgacc actagataaa acgttgtgaa attcctttct cataaattcc
    29941 ataactttag tatattatat ttaagcacta aagtacaaag aaagcaactg aaagcaatga
    30001 ttttcaccac tgctttcaga tttattttga attgttaaat agctattcct atccactatt
    30061 cttgaataga aacacaagat gcaatcttta ttccagactc attttttcaa atttattcac
    30121 catccagcaa gagctctttt ggttgttttc taaggagatt gcttgaagca agcgccataa
    30181 cgagaaccac tagaaccaag gcaaggacaa aaatgatgat aaagtctgat gtctgaatgg
    30241 aaatgtctag gctcgacaag gtcttgctaa agccatctac ttctgcaccg ccaccaaggt
    30301 tagaggcttg agccgcctta ctagcctgtt tggcaacacc tgaagtcaca ttggcaagga
    30361 cagtgtttcc aattgcacgg gcagtgtaat tagctaggaa gtaagcagaa actagagcag
    30421 ggatagcaat caagatagat tcggtgatga attgacccaa gatacttgcc tgcttgaggc
    30481 cgatagagag gagaattccc acttccttgc gacgggcgtt gatccaaagg ctgagcaaga
    30541 gggcaaggag gagaactgag aagctcaagc taccccagaa gaggaggttg gccatcttgt
    30601 acataccaga gatagattgc tcaagagctg ggtagttaga ggagctcttg acgagtgtgt
    30661 agctcttcca gttgatacca ctgatgccat tcaactcttt cataacatca tccaagttct
    30721 tgtctgctgt tacaaagaag gttgcgtccc cataaatggc tgtgtcttct gtgtatccat
    30781 aaagttttgc agcagtgtga atgtctgtaa tagctgtgtt ttcgtaaagt tcttgtgagt
    30841 aggttactgc tgacttatta tgaccatcaa agagtccctt gattgtcact tcaactgttt
    30901 ccttggctcc tttttcatta tctgcatcgt agatattaga gtccagttta accttgtccc
    30961 ctactttcca gccgtgtttg gctgccaagt ccttgtgcaa gaggatttta tccttgtcgt
    31021 cgttggttaa gtgctctcct tcgactagtt tataagaacc agagacaaac ttgtcttctt
    31081 tagaggagtc attgacacct gtaatcatca agctacttcc aaaacgtttg gcacgatcag
    31141 cagtgagatt cttcttggtt tctggcgttt caatcaggtc atatccagtc aaatctccga
    31201 tagcgttgat acgtttgaca taagactcaa tggccttgtt ttcggtgatt tttttgatat
    31261 cttcaccctt gatattccca gcaccacgag gcgttccttg gttgacgcga cgattgattt
    31321 gcatggagaa gctattggtg atatttttaa aggtctcctg agaagccttg gcagtagctc
    31381 ccttgattga caagccgacc aaactcaagc tcgccatgag gagaataatc aggaagatga
    31441 caatcgattt gaaaaacttc cttgtaacat aggcaaatgc gttgtgtaac atagattccc
    31501 tttctagatt ttgttttaat cattctatca aaataagctc aaattattta ctagtattgc
    31561 gcgtttcagt cagtttctta tcctttaatt caagtgtaat atctgacgct tgtgccactt
    31621 ctttactgtg agttacgaca atcacacatt tacctgtttt ctgggcaagt gatttgagta
    31681 gttcgacaat atctccagca gttttaggat ccagatttcc tgttggctca tcagctagaa
    31741 taactggagc ttctgagacc aaactgcgag caatggcaac acgttgctgt tgaccacctg
    31801 ataactggag aacattccgc ttgatctggc tttcatccaa accaagctca agaagtgtat
    31861 tcttgcttgc ctttttgttg accaatcgga tattttccag cggagaaaga taatctatca
    31921 agttataatt ttgaaagacc agggaaatat ggtgcatgcg atggtaagaa tagcccttct
    31981 tacgaatatc ctctccttga aaaaggatag aaccttcaac aggactatct agaccagcaa
    32041 gtagggacaa gagtgtggat tttcctgctc ctgactcccc aataatactg taaaattttc
    32101 cgggttcaaa attataatcg atctgatata ggactgcttc agcagtattc ttataacggt
    32161 aggtaacatc ttgtaattgt aataaagtca tgatttctcc ttcttaacta atagatgata
    32221 aaatttcttt cggtgatttt ctaaataaga ataggaaaca aagggctaca gataagcaac
    32281 taagcagaac tagaaaaaca taggattctg caaaagataa gatgctagtt gataaactgc
    32341 ttgctttggc tagtgtatct tgtaagctta cctgatctcc acttgctagt agagtttgga
    32401 gtaggtaagt tgtgattccg tttcctgcaa caaatgctgg aagcaaagct ccaagagata
    32461 ccaaaactac ctctaaacag aattgtagga agatcgagct cttgcctttt ccaagtgcaa
    32521 gtaaaatccc cacttcatag acccgttctc tcaaccagag agacaaaacc agaattaagg
    32581 ctccagctcc tgctatcaac atcccataaa ggaagatggt caggaaggtt tggaaagttg
    32641 caactgagtc tttgatttgt tcaaaagcct tgttttcctt ttcgacttgg tagccttgat
    32701 tttccaaggc caagttttct acctgcttca tgagtccgtc catttcctta ggattttcta
    32761 catagaagcg tgctgcactg acttgagctt cactattgcc caaaagggtt tggctacttt
    32821 cataatctgt aaagacttga ttttcactga agtcagaaga caagcctgtg aatttctctt
    32881 gttttttacc agaaaagatg ccgataatct caaactctac tgtttgtcct tttccagatt
    32941 cagactgacc agcatccaag ccaatcttgt catgaagtga aagaccgttc ttcttagcca
    33001 attcttcgtg gataaggatt ttcttggaat cccctttttg aaggtgtcgc ccttctttta
    33061 gattgaaagc cgaactggta aaggttacat ccttggatga atcctcaaga gccgttaagc
    33121 taaccaagtt attgtctgca gctgataaat catcacgctc cacgctctgc tcgccagtca
    33181 ctgcttcctt gtcttttagt tttgcgaccg tctcaagttc aggagagaca ttttccagcc
    33241 ccttaatctt gcttacagat gctaggtctg acaacttgaa tgtctgacca ttctctatct
    33301 tcttaataga aaaagatgta ttgagtgatt tataaagatt gctttctact gttttgttgg
    33361 acttcatcag agtcaaacag gctgaaattc cggccaataa gaccaataaa atcagaaata
    33421 aaataaaact tctcagtcgc tttctgctga cataagccca agatctttgg attggattca
    33481 tttgtcacct ccatatttgt aagactatta taaaacccaa atatgaaatg tttatgaaat
    33541 acgaaaaaaa aaa
//
LOCUS       DAVLMQ010000018        32602 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000018 DAVLMQ010000000
VERSION     DAVLMQ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.018"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            69..284
                     /locus_tag="VXF95_001050"
     CDS             69..284
                     /locus_tag="VXF95_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081615.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(393..1133)
                     /locus_tag="VXF95_001051"
     CDS             complement(393..1133)
                     /locus_tag="VXF95_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1081616.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(1133..2698)
                     /locus_tag="VXF95_001052"
     CDS             complement(1133..2698)
                     /locus_tag="VXF95_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1081617.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEIAFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYD
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTITGLIIGLAIGVFRTAPLSENKVIYS
                     LQKLVGWILNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMCKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            2836..4725
                     /locus_tag="VXF95_001053"
     CDS             2836..4725
                     /locus_tag="VXF95_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HEV1081618.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKVQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFREGTIEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVREKDQSKQLVTWVLPSILSISLLLSVCFYFIYRRKTTPSVK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVMDRG
                     NVSIISEGDAVGLRLVKEDGLSRFERDCLNLAFSGKKEATLSNLFADYKVSDSLYRGA
                     KAADEKRIQARGIQLKSSFEAVLKEMQEGVRKRVVFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            complement(5104..6054)
                     /locus_tag="VXF95_001054"
     CDS             complement(5104..6054)
                     /locus_tag="VXF95_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HEV1081619.1"
                     /translation="MLYVGIDVAKNKHDVTALNVPGKTVLKPLTFSNNKAGFELLDLS
                     FRQLNQDCLIALEDTGHYAFNLLNFLHEQGYKVYTYTPLLIKEFAKSLSLRKTKTDKK
                     DAHGIALKLLSDPNREQFQHDNRQIELKILARHIHRLKKKQSDWKVQYTRCLDIIFPE
                     LDKIVGKHSEYTYQLLTRYPNPQKRLEAGFDKLIEIKRLTASKIQDILSVAPRSIGTT
                     SPAREFEIIEIIKHYKRLIDKAETCVNDLMAEFNSVITTVTGIGGRLGAVILAEIRNI
                     HAFDNPAQLQAFAGLDSSIYQSDQIDLAGRMVKRSSPHLR"
     gene            6310..7155
                     /locus_tag="VXF95_001055"
     CDS             6310..7155
                     /locus_tag="VXF95_001055"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HEV1081620.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTNRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            complement(7302..8363)
                     /gene="dinB"
                     /locus_tag="VXF95_001056"
     CDS             complement(7302..8363)
                     /gene="dinB"
                     /locus_tag="VXF95_001056"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HEV1081621.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAEDFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITMTGF"
     gene            8758..11082
                     /gene="pflB"
                     /locus_tag="VXF95_001057"
     CDS             8758..11082
                     /gene="pflB"
                     /locus_tag="VXF95_001057"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HEV1081622.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIEPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            complement(11450..11668)
                     /locus_tag="VXF95_001058"
     CDS             complement(11450..11668)
                     /locus_tag="VXF95_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081623.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(11764..12012)
                     /locus_tag="VXF95_001059"
     CDS             complement(11764..12012)
                     /locus_tag="VXF95_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081624.1"
                     /translation="MDKMKPVFQALNKELIQENLTLTIICVDGYVLEYHGLRATQDVD
                     AFYDQNQKINEIIARVGKQFNLNIHEELWLNNHVAKQI"
     gene            complement(12005..12289)
                     /locus_tag="VXF95_001060"
     CDS             complement(12005..12289)
                     /locus_tag="VXF95_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081625.1"
                     /translation="MVWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            complement(12901..13071)
                     /locus_tag="VXF95_001061"
     CDS             complement(12901..13071)
                     /locus_tag="VXF95_001061"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1081626.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEKAG"
     gene            13632..14090
                     /locus_tag="VXF95_001062"
     CDS             13632..14090
                     /locus_tag="VXF95_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS alpha-glucoside transporter subunit IIB"
                     /protein_id="HEV1081627.1"
                     /translation="MEVVLFSYCLNTRYLLQIVDIASSNDIILEEDTSEIMPGEIDVI
                     KSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIILA
                     PQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKSLQFVLEHYQAV"
     gene            complement(14216..15655)
                     /locus_tag="VXF95_001063"
     CDS             complement(14216..15655)
                     /locus_tag="VXF95_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HEV1081628.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNQTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(15659..17008)
                     /gene="trkA"
                     /locus_tag="VXF95_001064"
     CDS             complement(15659..17008)
                     /gene="trkA"
                     /locus_tag="VXF95_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HEV1081629.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVSRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            17197..18045
                     /locus_tag="VXF95_001065"
     CDS             17197..18045
                     /locus_tag="VXF95_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HEV1081630.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            18060..18608
                     /locus_tag="VXF95_001066"
     CDS             18060..18608
                     /locus_tag="VXF95_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HEV1081631.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            18615..18863
                     /locus_tag="VXF95_001067"
     CDS             18615..18863
                     /locus_tag="VXF95_001067"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081632.1"
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVS
                     NHTYGKAKLTWFEEIFEEYKMMGKAGQLVFFDVYRLVR"
     gene            18974..20656
                     /locus_tag="VXF95_001068"
     CDS             18974..20656
                     /locus_tag="VXF95_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081633.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLANLDNMSIS
                     KGQVQLQNELAKETPELQSLFKLEDVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
     gene            20641..21471
                     /locus_tag="VXF95_001069"
     CDS             20641..21471
                     /locus_tag="VXF95_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HEV1081634.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            21664..22167
                     /locus_tag="VXF95_001070"
     CDS             21664..22167
                     /locus_tag="VXF95_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HEV1081635.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKIYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     regulatory      22221..22455
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            22620..23183
                     /locus_tag="VXF95_001071"
     CDS             22620..23183
                     /locus_tag="VXF95_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1081636.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTIGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     gene            23197..23823
                     /locus_tag="VXF95_001072"
     CDS             23197..23823
                     /locus_tag="VXF95_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1081637.1"
                     /translation="MKGSFALLLFVILGYMVKFYPETLVNFDQSIQTAIRGDLPDYLT
                     ILFRALTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPDILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            23851..24240
                     /locus_tag="VXF95_001073"
     CDS             23851..24240
                     /locus_tag="VXF95_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HEV1081638.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQTLLADRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            24245..24694
                     /locus_tag="VXF95_001074"
     CDS             24245..24694
                     /locus_tag="VXF95_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HEV1081639.1"
                     /translation="MCFVPYYKVNHCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGMSFILELV"
     gene            24822..25409
                     /locus_tag="VXF95_001075"
     CDS             24822..25409
                     /locus_tag="VXF95_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HEV1081640.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            25787..27394
                     /locus_tag="VXF95_001076"
     CDS             25787..27394
                     /locus_tag="VXF95_001076"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HEV1081641.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            27809..28405
                     /locus_tag="VXF95_001077"
                     /pseudo
     CDS             27809..28405
                     /locus_tag="VXF95_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466308.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            28562..28930
                     /locus_tag="VXF95_001078"
     CDS             28562..28930
                     /locus_tag="VXF95_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1081642.1"
                     /translation="MAVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKAK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
     gene            28943..29329
                     /locus_tag="VXF95_001079"
     CDS             28943..29329
                     /locus_tag="VXF95_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081643.1"
                     /translation="MSEIEIINAKKIYHDVPVIENLNITIPKGSLFTLLGASGCGKTT
                     LLRMIAGFNSIKDGEFYFDDTKINNMEPSKRNIGLVFQNYAIFPHLTVRDNVAFGLMQ
                     KKVPKEELIQQTNKYLELMQIAQYAD"
     gene            29336..29425
                     /locus_tag="VXF95_001080"
                     /pseudo
     CDS             29336..29425
                     /locus_tag="VXF95_001080"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            29411..30034
                     /locus_tag="VXF95_001081"
     CDS             29411..30034
                     /locus_tag="VXF95_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081644.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIRAIQHEVGITTVYVTHDQEEAMAI
                     SDQIAAMKDGVIQQIGRPKELYHKPANEFVATFIGCTNIIPTNLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            30024..31659
                     /locus_tag="VXF95_001082"
                     /pseudo
     CDS             30024..31659
                     /locus_tag="VXF95_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(31762..32454)
                     /locus_tag="VXF95_001083"
     CDS             complement(31762..32454)
                     /locus_tag="VXF95_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1081645.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
BASE COUNT         9640 a         6149 c         6876 g         9937 t
ORIGIN      
        1 tttttattga caaaagtagt aaaaacgtat acaattaaat attataaaga agaaaatagg
       61 agaaaaacat ggctaagtca aactttgaaa aagtagaatc agttgttggc tgggttcgtg
      121 ataagaaaat cacaggctac cgtatctcta aagaaacgaa tgcgcgtgaa atgtctatca
      181 ttgctctggc gcagggtcgt gcaaaagtaa aaaatatttc atttgaaaca gccctaggcc
      241 taattgattt ctatgaaaaa aattatgaaa aatttgaaga ttaatctttg gataacggcg
      301 gattcttgac cttcaagtag tagagataga gaatctgcct tttcattttg aggacagcaa
      361 aaagactgca cggttgatgc agccttttct ttttatttga gatagcgttg aaggaactct
      421 tttgttcggt cttctttagg attggtgaag aggtcttctg gtttaccttc ttcagcgatc
      481 acgcccttat ccataaagat aacacggtga gagacatcac gggcaaattc catttcatgg
      541 gttacgacaa tcatggtcaa gccttcctga gccaggtcct gcatgatttt gaggacttct
      601 ccaaccattt ctggatcgag agctgatgtt ggttcatcaa agagaatagc gtccggattc
      661 atggagaggg cacgagcgat ggccacacgt tgtttttgac cacctgagag ttgttttggt
      721 ttggcttgcc agtagcgttc tcccatgccg accttttcca ggttttcttt ggcaatcttt
      781 tcagcttctg tgcgttcgcg ttttaggaca gttgtctgag cgacgattgt gttttcaaga
      841 acattgagat tttcaaagag gttaaaggat tggaaaacca tccccaactt ttcacggtat
      901 tgcgtgaggt catagccttt ttcgaggacg ttttgtccat gataaaggat ttgtccatca
      961 gttggtgttt caagtaggtt aatggagcgt aggaaggtcg attttccgct tccagagctt
     1021 ccgatgatag agatgacctc tcccttgtgg acagtgagtg aaatgtcttt tagcacttcg
     1081 ttttgtccat aggatttttt gaggtgttta atttcaagga ttgcttgtgt cattatttca
     1141 aatcctccgt ttgcatttgg ttagcacctg tagtgtaggt atccatgtcc attctgcgct
     1201 cgataaagcg taggatacgt gttacggtga aggtgaggac aaagtaaatc acggcgatga
     1261 ttgtaaatgt ctggaagtat tgataggttt gtgttgccac ggtatttcct gagaaataaa
     1321 gctcgacaac agagataacg ttcaatacag atgtatcttt gatattgatg acaaattcat
     1381 taccagttgc tggtaggata ttgcggacaa cctgaggtag gacaatctta cacatggttt
     1441 ggttatgagt cataccaaga gcagtcgcag cttcaaattg tcccttgtca actgccagga
     1501 taccaccacg gacgatttca gtcatgtagg caccggtatt gattgaaacg atgaagatag
     1561 cagccagtgt acggtcaagg ttgataccga aagcttgggc agttccatag tagataacca
     1621 tcgattgaac aatcattggc gtaccacgga aaatttcaat gtagacgttg aggatccagc
     1681 cgactagttt ttgcaggctg taaatgactt tgttttcaga gagaggagca gtacggaaaa
     1741 caccaatggc aagtccaata atgagacctg tgatggttcc gacgatagag attaaaagag
     1801 tgataccagc accacgcaag agttgttgcc agttttcaga aagaatttta gcgacttggc
     1861 taaagaaact actgctagtc tcttcagttg ttgtagcttc ggcaggttgt tccttgatca
     1921 tacgatccat caaggcaact tggtcatctt ttgaaatggt ttcaatgctg gcattgattt
     1981 ggctaatacg attgtcattt ttacgaagcc cgatagcgat agctgtatct tcttccccag
     2041 ttttgaaacc aggttctact tgaatcatct tgaacttaga gttcgcagct tcagcagtca
     2101 gtgcttctgg acgttcagaa acataagcat caatgacacc agcctcaaga gcttggcgca
     2161 tttgagcgaa gtctcccatg gctgtttctt ttttagcacc tgggatttgt gcaatcaagt
     2221 cgtagaggta gaccccttgt tgagaagtga tttttgcacc gttaaagtca tccaaagatt
     2281 tagcacttgc gtaggcagaa tcttttttga caagcaaaac tggttcgcta gtgtagtaac
     2341 tgctcgaaaa ggcaatttct tgtttgcgtt ctgcagttgg actcatacct gcgataatca
     2401 tgtcaatctt accagaagta agggcaggga ctagaccttc ccacttggtt ttaacaacca
     2461 aaggttcttt acctaagtcc ttagcgattt tcttggcgat ttgaacatcg tatccgttgg
     2521 catactgatt ggtcccatcg attttgacag ctccgttgct atcatcatcc tgggtccagt
     2581 taaagggagc atatgctgct tccatcccga tgcgtaaata ttcatcggct tgagcaacat
     2641 tgacaagtcc tagcatcagc aagagacttg tgaaaataga taagtatatt tttctcatga
     2701 tttctcctat tctgatctat taaaaaataa ctgtctccta ttttatcgaa aaatgcgtaa
     2761 tttttcaaca taagtaagcc tttacttacg aaaaaatgct ataatgataa gaaagataaa
     2821 aagggggctt agttgatgaa aaaaactttt ttcttactgg tgttaggctt gttttgcctt
     2881 cttccactct ctgtttttgc cattgatttc aagataaact cttatcaagg ggatttgtat
     2941 attcatgcag ataatacggc agagtttaga cagaagatag tttaccagtt tgaggaggac
     3001 tttaagggac aaatcgtggg acttggacgt gctggtaaga tgcctagcgg gtttgacatt
     3061 gaccctcatc caaaggttca ggccgcgaaa aacggtgcag aactagcaga tgtgactagc
     3121 gaagtaacag aagaagcgga tggttatact gtgagagtct ataatccagg tcaggagggc
     3181 gacatagttg aagttgacct cgtctggaac ttaaaaaatt tacttttcct ttatgatgat
     3241 atcgctgaat taaattggca acctctgaca gatagttcag agtctattga aaagtttgaa
     3301 tttcatgtaa ggggagacaa gggggctgaa aaactctttt tccatacagg gaaacttttt
     3361 agagagggaa cgattgaaaa gagtaacctt gattatacta tccgtttaga caatcttccg
     3421 gctaagcgtg gagttgagtt gcatgcctac tggcctcgga ccgattttgc tagcgctagg
     3481 gatcagggat tgaaagggaa tcgtttagaa gagtttaata agatagaaga ctcgattgtt
     3541 agagaaaaag atcagagtaa acaacttgtt acttgggtcc tcccttcgat cctttctatc
     3601 tccttgttat tgagtgtctg cttctatttt atttatagaa gaaagaccac tccttcagtc
     3661 aaatatgcca aaaatcatcg tctctatgaa ccaccaatgg aattagagcc tatggtttta
     3721 tcagaggctg tctactcgac ctccttggag gaagtgagtc ccttagtcaa gggggctggc
     3781 aaattcactt ttgaccaact tattcaagct accttgctag atgtgatgga ccgtgggaat
     3841 gtttctatta tttcagaagg agatgcagtt ggcttgagat tggtgaaaga agatggtttg
     3901 tcaagatttg agagagactg tctaaatcta gccttttcag gcaaaaaaga agccactctt
     3961 tccaatttgt ttgcggatta caaggtatct gacagccttt atcgcggagc taaagctgct
     4021 gatgagaaac ggattcaagc aagagggatt cagctcaaat cttctttcga agcagtatta
     4081 aaagagatgc aagaaggagt gagaaagcga gttgtcttct ggggactccc agattactat
     4141 cgtcctttaa ctggtttgga aaaggctttg caagtgggta tgggtgtctt gactatcttg
     4201 cccctattta tcggatttgg tttgttcttg tacagtttag acgttcatgg ctatctttac
     4261 ctccctttgc caatacttgg ttttctaggg ttagttttgt ctgttttcta ttattggaag
     4321 cttcgactag ataatcgtga tggtgttcta aatgaagcgg gagctgaggt ctactatctc
     4381 tggaccagtt ttgaaaatat gttacgtgag attgcacgac tggataaggc tgaattggaa
     4441 agtattgttg tttggaatcg tctcttggtc tatgcaacct tatttggcta tgcggacaag
     4501 gttagtcatt tgatgaaggt tcatcagatt caagttgaaa atccagatat caatctctat
     4561 gtagcttatg gctggcacag tatgttttat cattcaagcg cgcaaatgag ccattatgct
     4621 agtgtcgcaa atacagcaag tacctactct gtatcttctg gaagtggaag ttctggtggt
     4681 ggcttctctg gaggcggagg tggcggcagt atcggagcct tttaaagaga gctaccatag
     4741 actgaaaaag tatgatataa tggaagatag aagaaagaca aactataaga aaagtcaata
     4801 gttttatcta aactatttct tatttcaatt tgatgatttg gcgatgattt tagagcacgg
     4861 caaaaagccc ttgaaaaagt ccattttttc aaaggtaatc ctgtgttaat ttcagaaatt
     4921 acatcacttt ttgttcgtca aatggcagct cttttttagg atataaaaca gggttcggat
     4981 aagttttttt gcaaggtgga tgatggctac attgtaatgt tttccttatt ctaacttagt
     5041 cttaagatag gccttaaaag caggtgaaaa gcgagggcat gctttggcag cttgtatgag
     5101 tacctaccgc agatgagggg aactccgttt gaccattctt cctgctaaat caatctgatc
     5161 tgactgataa atagaagaat ccagtccagc gaaagcttgt aattgagcag gattatcaaa
     5221 ggcatgaata tttcgaatct cggctaaaat gaccgcccct aaacgacccc caatcccagt
     5281 aaccgtcgtg atgaccgagt tgaactcagc catcaagtca ttgacacatg tttccgcctt
     5341 gtcaatgagc ctcttgtaat gtttgatgat ttcgatgatt tcgaattcac gagcaggaga
     5401 tgttgttccg atagaacgag gtgcgactga gaggatatcc tgaattttag aagcggtcaa
     5461 tcgcttaatt tctatcagct tatcaaatcc tgcctcaagc cttttctgag gattagggta
     5521 gcgtgtcaag agttggtagg tatattctga atgctttcca acgattttat ccaactcagg
     5581 aaagatgata tcaagacaac gagtgtattg tactttccaa tcagactgtt ttttcttgag
     5641 acgatgaata tgtctagcca gtatttttag ttctatttgc cgattatcgt gttgaaattg
     5701 ttcacgattg gggtcagaaa gaagtttaag agcgatgcca tgagcgtctt tcttatccgt
     5761 tttagtcttg cgaagtgata atgatttggc aaattccttg atgagcaaag gagtgtaggt
     5821 gtaaacttta tatccttgtt catgcaggaa gttcagtaga ttaaaggcat aatgtccagt
     5881 atcttcaaga gcgatgagac agtcttggtt gagctgtcga aaagacagat ctaagagttc
     5941 aaaaccagct ttattatttg aaaaagtgag tggtttaaga acagtttttc ctggaacatt
     6001 caaggctgta acatcgtgtt tatttttagc gacatcaatg cccacataaa gcatgggagt
     6061 acctccagat atagtatttc aagtctactt ggttatccac gaactttttg ccttgttacc
     6121 ttagacgaga taaaacgtct atgcgttatc aaactcatta ccaattgaaa caaaaagctg
     6181 tggttagacc ctttcggaaa tcgtcaagcg attggaggaa atgaactaat ccacagtggc
     6241 ttattccaag tataccactt gggctttggc agtagctaac tgcgttaaat ataatataag
     6301 gagaaatata tgtatcttat tgaaatttta aaatctatct tcttcgggat tgttgaagga
     6361 attacggaat ggttgccgat ttccagtaca ggtcacttga ttttagcaga ggagtttatc
     6421 caataccaaa atcaaaatga agcctttatg tccatgttta atgtcgtgat tcagcttggt
     6481 gctattttag cagttatggt gatttatttt aacaagctca atccttttaa accgactaag
     6541 gacaaacagg aagttcgtaa gacttggaga ctatggttga aggtcttgat tgccactttg
     6601 cctttacttg gtgtctttaa atttgatgat tggtttgata cccacttcca taacatggtt
     6661 tcagttgctc tcatgttgat tatctacggg gttgccttca tctatttgga aaagcgcaat
     6721 aaagcgcgtg ctatcgagcc aagtgtaaca gagttggaca agcttcctta tacgaccgct
     6781 ttctatatcg gactcttcca agttcttgct cttttaccag ggactagccg ttcaggtgca
     6841 acgattgtcg gtggtttgtt aaatggaacc aatcgttcag ttgtgacaga atttaccttc
     6901 tatcttggga ttcccgttat gtttggagct agtgccttaa agattttcaa atttgtgaaa
     6961 gccggagaac tcttgagctt tgggcaattg tttttgctct tggtcgcgat gggagtagct
     7021 tttgcggtca gcatggtggc tattcgcttc ttgaccagct atgtgaaaaa acacgacttc
     7081 accctttttg gtaaataccg tatcgtgctt ggtagtgttt tgctacttta cagttttgtc
     7141 cgtttatttg tataagaaaa accttgaagg ggcaactctt caaggtttta tactcttaga
     7201 aaatctcttc aaaccgcgtc agctttatct gcaacctcaa aacagtgttt tgagcagcct
     7261 gcggctagcc tcctagtttg ctctttgatt ttcattgagc tttaaaatcc agtcatggta
     7321 atccccaata ggcggacacc tctttctttc tcgcttaatt cttcatagag ttgcagggct
     7381 atttggctta tctgactagc atcttgtgtt ttttgagcaa gactttttcg tttggtaaga
     7441 gttgaaaagt cctcgtagcg gattttcaaa atgacaattt ttccagcttt ttcttgttga
     7501 tgtagattga gagcgacttt ttctgataga agagtcagct cttttttgat atcttcctca
     7561 gcacggagaa tcttcccgta ggttttctcc ttgccgattg atttacggat gcgattggat
     7621 ttgactggag agttgtgaat gccacgagcc tttcgataca gatcatagcc tagtctacca
     7681 aaacggtcta ttagggtcac ctcaggaact tcaagtaaat cagcaccagt aaaaacgccc
     7741 atttgatgaa gacgttctac tgtctttttt cctactccat gaaatttgga aatatccatt
     7801 tgtttgagaa aatcctcagc ctgttcaggt agaatcactg tcaaaccatg aggtttttga
     7861 taatcactcg ccattttagc taagaacttg ttataggaaa taccggcaga agcagttaga
     7921 tggagttctt gccagatatc tttttgaatg aggcgagcaa ttttgaccgc tgacttgata
     7981 ccgagtttat tttctgtcac atccaaatag gcttcgtcaa tactcatggg ttcaatcaaa
     8041 tctgtatagc gcttaaaaat agctcgaatc tggagtccca cagctttgta tttctcataa
     8101 tttcctgaga taaagacggc ctggggacaa cgttcataag cttccttgga actcatggca
     8161 gaatggacac caaaagctcg agcctcatag ctacaggtag aaacgactcc ccgcccacct
     8221 gtttgtcgag ggtcgcttcc aataatgaca ggttttcctc tgagtttagg attatccttg
     8281 atttccaccg cagcaaaaaa ggcatccatg tcaatatgga tgatttttct tgacaaatca
     8341 tttaacaaag gaaaaatcaa catgcctagc acctttttat acttttcaaa aatctcttca
     8401 aaccacgtca gcttccatct gcaacctcaa aacagtattt tgagctgact tcgtcagttc
     8461 tatttacaac ctcaaagcag tgctttgagc agcctgcggc tagcttccta gtttgctttt
     8521 cgatttccat tgagtgttac tgcttatttt cttttattat accctttttt ctgaaaaaaa
     8581 gaaaaaagga ctttattttt ttcaaaaata taatacagtt tgaaataaaa tatagactgt
     8641 tttagaaaag aaagtgtaaa aatagggatt ttgcacttgt tgaaatcggt tactttatgg
     8701 tatacttgtc ttatgaatgt aacagatgac tgttactaga aaaaagagga cattaatatg
     8761 gttgttaaga cagttgttga agcacaagat atttttgaca aagcttggga aggcttcaaa
     8821 ggcgtagatt ggaaagaaaa agcaagtgta tcacgctttg tacaagctaa ctacacacct
     8881 tatgatggag acgaaagctt ccttgcagga ccaacagagc gttcacttca catcaagaaa
     8941 attgtagaag aaactaaagc acactacgaa gaaactcgtt tcccaatgga cactcgtcca
     9001 acatctatcg ctgatatccc tgctggattt atcgacaaag aaaatgaagt tatctttggt
     9061 atccaaaatg atgaactctt caaattgaac ttcatgccaa aaggtggtat ccgtatggct
     9121 gaaactactt taaaagaaaa tggatacgaa ccagacccag ctgttcacga aatcttcact
     9181 aaatatgtaa caacagttaa cgacggtatt ttccgtgcct acacttcaaa tattcgtcgc
     9241 gctcgtcacg cacacactgt aactggtctt ccagatgcat actcacgcgg acgtatcatc
     9301 ggtgtttacg cacgtcttgc tctttacggt gcagactact tgatgcaaga aaaagtaaac
     9361 gactggaatg caatcaaaga aatcgatgaa gaaacaatcc gtcttcgtga agaagtaaac
     9421 cttcaatacc aagcattgca acaagttgtt cgcctgggtg acctttacgg ggttgatgtt
     9481 cgcaaaccag cgatgaacgt gaaagaagca atccaatggg ttaacattgc tttcatggct
     9541 gtctgccgtg tgattaacgg tgctgctaca tctctaggtc gtgtaccaat cgtattggac
     9601 atctttgcag aacgtgacct tgctcgtggt acatttactg aatcagaaat ccaagaattc
     9661 gttgatgatt tcgttatgaa acttcgtaca gttaaatttg ctcgtacaaa agcttatgac
     9721 caattgtact caggtgaccc aacctttatc acaacttcta tggctggtat gggtaacgac
     9781 ggtcgtcacc gtgttactaa gatggactac cgtttcttga acactcttga caacatcggt
     9841 aactcaccag aaccaaactt gacagttctt tggactgaca aattgccata caacttccgt
     9901 cgctactgta tgcacatgag ccacaaacac tcttctatcc aatacgaagg tgtaacaaca
     9961 atggctaaag acggatatgg tgaaatgagc tgtatctcat gctgtgtgtc tccacttgat
    10021 ccagaaaatg aagaacaacg ccacaacatc cagtacttcg gtgctcgtgt aaacgttctt
    10081 aaagcccttc ttactggttt gaatggtggt tacgacgatg ttcacaaaga ctacaaagta
    10141 tttgatatcg aaccaatccg tgacgaagtt cttgaattcg aatcagttaa agcgaacttt
    10201 gaaaaatctc ttgactggtt gactgacact tacgtagatg ccttgaacat catccactac
    10261 atgactgata ggtacaacta cgaagctgtt caaatggcct tcttgccaac taaacaacgt
    10321 gccaacatgg gattcggtat ctgtggattt gctaacactg ttgatacatt gtcagctatc
    10381 aaatacgcta cagttaaacc aatccgtgac gaagatggct acatctacga ttacgaaaca
    10441 atcggtgact acccacgctg gggtgaagat gacccacgtt caaacgaatt ggcagaatgg
    10501 ttgatcgaag cctacacaac tcgtctacgt agccacaaac tatacaaaga cgcagaagct
    10561 acagtatcac ttttgacaat cacatctaac gttgcttact ctaaacaaac tggtaactca
    10621 ccagttcaca aaggtgtata cctcaacgaa gatggttctg tgaacttgtc taaacttgaa
    10681 ttcttctcac caggtgctaa cccatctaac aaagctaaag gtggttggtt gcaaaacttg
    10741 aactcacttt ctagccttga ctttagttat gcagctgacg gtatctcatt gactacacaa
    10801 gtatcacctc gcgctcttgg taagactcgt gatgaacaag ttgataactt ggtaacaatc
    10861 cttgatggtt acttcgaaaa cggtggacaa cacgttaact tgaacgttat ggacttgaac
    10921 gatgtttacg aaaagatcat gtcaggcgaa gacgttatcg tacgtatctc tggatactgt
    10981 gtaaacacta aatacctcac tccagaacaa aaaactgaat tgacacaacg tgtcttccac
    11041 gaagttcttt caatggatga cgccttggat gcattgagct aatcaagttc ttgaataatg
    11101 aaaaggaacc ctcggtcaaa cgactgaggg ttttgtgctt gggatagtgt gagcaattcc
    11161 ttcggcgcaa tatgcaatgt ttttgggaag gaatagtgga ccgaatctga aatataatag
    11221 attgaaacta gaatagtaca cctttatttc taaaacattc ttagaaatcg atttgactgt
    11281 cctgatcgat ttgtcctatt cttatttcat tttactatag tccactgaaa cgtctcaaac
    11341 agcgctagaa attgactgga attctctaag cgatttgttc agattttatt tcatttcatc
    11401 ataaaaaaca agacgactgg ctaattgaca atcatcttgt ttgatactgt taataaaatt
    11461 cgcgaagttt atcttgattt tctttaaaaa atttttctaa ccaatccata ccataagcat
    11521 aactaaaacc ttctaataga acagagaggt caatagtatc aaatcccatg tcttttaaat
    11581 atttaaaggt atcgaatggt gaatgaaagt ttttgtattt aataattgca ccaatatctt
    11641 gcaaatcctg ctctctgata ctcatcatct tcattcctaa cacatactca atagggacta
    11701 ctaaaacggt cagattctca aatgagtaca aggattcgca taaacttaag ggaggttgtt
    11761 tgttcatatt tgctttgcaa catgattgtt gagccataac tcttcgtgga tgttaagatt
    11821 aaactgtttt cctacacgag caataatttc attgattttc tgattttggt cataaaaagc
    11881 atcaacatct tgtgtggcac gtaaaccatg atattctaag acataaccat cgacacagat
    11941 aattgttaaa gtcagatttt cctgaattaa ttccttattt agggcttgga agaccggttt
    12001 cattttatcc atgtttgtat ttctccatca atttttgaac attggttaac ttagcaggtt
    12061 tatttaatga aatcacatat ttatgagttg gagtatgctc ttgaaaggca tacttcaagc
    12121 taattttttg aaaacgggtt agttctttgg agtctagcaa cttttctaca tcttggtttg
    12181 ttaaataaga atagtcttca aaaataactt ttcgcaaata gcgaaaccaa tggcttgcgt
    12241 tgaattgtga ttgtttggat gcctgtatca tataatcgta ccaaaccatt gtcttcctcc
    12301 tataaaattt agtttatatt attgtagttt atattcaaaa atgtagtttt tcttaattag
    12361 ctcgtatcta taggatgata ctgaaaatct tcttgttgct ttaaatcaca atcgaaaaat
    12421 tctgtttttc atcttagaaa agaatgttta gaaatgtaaa atgaaccttt tttcttatcc
    12481 gaaaacctta ctaaagtata taatttagga agtcaattct gtatgataat gtttgtacta
    12541 tcgtcgagtt tttgcttgat tgcctaacga gataaatttt agaagaattt tcggtgtgat
    12601 ttgacaagct tctgactgga aggatagtta cactagtatt gtttattaaa atgagcagat
    12661 agagaaaatt tggaatctat ttgcttatta tcaatcgttt ttttagctta tttgtcttag
    12721 attggtatag aactgatcta tggattaatc ctcttgtatc ttatcctgtt cctaaatatg
    12781 ttggtagaaa aatgaagcag ttgttacgag tgtctgtatt gggaaaaatt ttgtctatac
    12841 aattctttaa atgatatgaa ggctaggaat gccaaaacac tgacatattt cgtttaaagc
    12901 ctatccagcc ttttcaattg tatttgtaga aatgctatca gtaatatatt cgcgaacact
    12961 atgatttaca acagtgtggt cgtacatctt tgtaacttta ttatacaaca accatttaca
    13021 ggtgtaaagt tgagcagtgt ctttagtaaa tttagggact tgttttgtca tagttttgat
    13081 acctgtattc gttgtttcat gagtatttga cgtttctttt catgtaggca tttcaacaat
    13141 tagaatgata tttttccgag gatgaactta tatattgtga ctttttagag ttatgatgcc
    13201 tcttgatttg actatcgcta tcaatttcat ccacttttac agtttcatgg ttttatgaac
    13261 cgaaacatct aggtacaggt tttagcatca attgattgtt tttgagccat atgaagttga
    13321 aacgtggaga tgcttttctt gtgataacgc cctattcaaa gaggcataac cgtttttgga
    13381 gagagttcag tactatgtgg cgctaaatac tatatgtaaa acatatatta aacaagattt
    13441 aactaaggag aattgtaaaa acaaaaatga gaatttcata taaagtttat tctaggagta
    13501 tgtatcttga ataaaaattg ttatttaagt tctgggggtt atgatgaatg tttttataat
    13561 aataaaatgc agctagaaga aaagttattt taatataaat cactcaacat agcgagaagg
    13621 cggtttccta tatggaagtc gtcttgtttt catattgtct aaatacgaga tatttactac
    13681 agattgtaga tattgcaagc tcaaatgata ttattttaga ggaggataca agtgaaataa
    13741 tgcctggtga gatagatgta ataaaaagta aggagttgaa agtactggtt ctttgtgcag
    13801 ggtctggaac aagtgcgcaa ttagccaatg caattaacga gggcgctcaa ttagcagaag
    13861 ttagagtgat tgcgaattca ggagcgtacg gagctcatta tgatattatg ggtgtttatg
    13921 atttaattat tctggctcca caagttcgga gttattatag agagatgaag gtggatgcag
    13981 aaagattagg tattcagata gttgctacca gaggaatgga atatattcat ttaacaaaga
    14041 gtccaagtaa atccttacaa tttgtattgg agcattacca agctgtgtag taagtttttc
    14101 catcttttat ttgagtaagg attttgctta cagataggct tggatttaaa aacgttcccc
    14161 cttttttaat ataagaatcc ctctttcaca attgtaaaaa gagggatttt gtattttatc
    14221 tcttagacca agttctcttc ataaagagaa ggaggattgg gtaaatctcc aagcgccctg
    14281 caatcattgc aaaggatagg agaatttttg agatgggact aaagattgag aaactagaag
    14341 tggttcctag aataggcccg atattattga aacagctaaa gacagcgctg gtcacgacca
    14401 gaaaatcatt gctatctagg ctgacaataa agataagcgc tagcaaaatc atagcataga
    14461 tgacaaagta cttgagaatc ttatgctggg tatctttatc aatcaccgtt tgattcacat
    14521 ggagggtcaa aacacggtgg ggcgatagga ttgacaaaat ttggtttttg gcaatttttg
    14581 aaaggatgag gcctcgaata atcttgagtc cacctgcagt tgatccagca gagccaccga
    14641 ttgccatgag gaaaaggagg ataaactggg agaagagggg ccagttggta atatctccat
    14701 atccaaaacc agttgttgta atgatgttgg aaacctggaa gaaggtcatt tcaaagctct
    14761 ttgaaaaccc tgggtagagg tagagggtgt tgaggctaat caagcctgta gaaaccagta
    14821 caatgaccaa gtaagcccga agttcttcgt caccaaagaa ggccttgatg cgacggagca
    14881 tgaggtagta gtagaggttg aaatttaccc caaaaaccag aactccgata ctgaccagat
    14941 aggtaatcag tgagctgcca tagtgggcaa ttccgtcgtt atagacggta aagcctccag
    15001 ttcccgctgt ccccatagca atgacaaaac tatcgtagag aggcatacca gctagataat
    15061 agatgatgac aaagagggag aagagagcta gataaaggag atagagaatc tgggcagtgt
    15121 tttttagttt ggatacaacc ttgccaaaaa caggacctgg aacctcagcc ttcatcacct
    15181 ctaggtggct atttttggca ttgtccataa tagcaagtgc aaaaacaagc actcccatcc
    15241 ctccaatcaa gtgggtaaaa cttcgccaga agaggaggga acggctgaga accgaaatgt
    15301 cgttcaaaat acttgctcca gtagttgtaa acccagaact aatttcaaaa aaggcatcaa
    15361 taacgctagg gatttgccca gaaaagacaa aggggagacc accaaagaaa gaccaaagga
    15421 tccaacagag ggcaacgatc aagactccct ccttggcata aatccgttga ttttttggct
    15481 tctgtaaact ccctgaaccg cctaacaata cgagaatccc tatggtcgaa aagagggctg
    15541 taaagacttg gctcgattca cggtaataga cagcgatagc cacaggaacc aagaggagaa
    15601 cagcttcaat caaaagtaac tttgaaagga ggtaacgaat catactttta ttcatttctt
    15661 acctcgcaat caagtcataa atcttggtga tgtttggcaa caaggttgtt actaggagct
    15721 tgtctccaac ttccaacata tcctccccag ttgggaaaat agtcttgccc tttcgaataa
    15781 tggctgcaat aagaacccct tttttcaatt tcagttgaga aagaggtttg gcagtcattt
    15841 tattggcttc cttgatatgg aattgcaggg tttcaatttg gccattggct agatggtgca
    15901 tggcttgaag gtctgaatac tgggcattaa ctcgaccacg aataaagtgc ataatcgtat
    15961 ctacagcgat gcttttaggt gtgatgatac ttgaaaaatc aggcgcattg ataatctcga
    16021 ggagactggt acgattgacc ttagtaatat ttttctgtac acctaccctg tcaaggaaca
    16081 tagatgtaat cagattttcc tcatcgacac ctgttagagt cgcaacggca tcatagtgtt
    16141 gagcactttc ttccagcagg atatcttttg cggttccatc tccttgaacg atgtagagat
    16201 ttgggaattt ctcgctaaag aagctggcga tttcaggatt gatttcaatg acttttgtat
    16261 cgatacgact atctttgaga ataccaagta gataataggc aattctacct gccccaacga
    16321 tgagaaggct cttcacggcg cgtgatttaa aataattatg gaagagtatc atatcgacac
    16381 ggttaccagt gacaaagatt ctatctttat cctgtacagt catgtcaccg cttggaatga
    16441 taatttgatg atccctctct atcgcacaga caatgacatt accaaatttt ttacgaaaat
    16501 cagaaatggg catttggcaa agaccgctgg tggacttgac gacaaattcc atgaggctaa
    16561 cgcgtccacc agcaaagcgt tcgacagaca gggcgttggg gaagtcaatg atattcgcga
    16621 tagcgcgggc agccaagagc tcaggattaa cgataagaga aaaaccgaga atattctttt
    16681 ccttgaaata agagttagaa tattcagggt tccgcacccg aacgatagtt tctttagctc
    16741 ccattttctt ggctagaact gctgcaatca tgttgacttc atcgtgctca gtcagggcga
    16801 taaagatatc acaatcttgg acgctggctt gctcaagaat ggcaaaatcg gccccattac
    16861 caaggatacc aatgatatca aagcgactga caatatgatt gagaacagct tcgtcttgct
    16921 caatcagcaa aacatcatgc ttttctgcaa ccaaggagcg acagagggca aaaccaactt
    16981 ttccccctcc gacaaggata attttcataa taaaacctac tttttcatga tgtaactatc
    17041 ataccctttt tcaagaaaaa atgcacctac tagctaataa caagaacttt tagtaggaaa
    17101 tttgctataa ggtaaaacta taccctaacc aattgaaata gctattagcg actttctctg
    17161 aaatatggta tgataaagga tatacaagga gataaaatga ataataattt actggtatta
    17221 caatcagact ttggtctggt tgatggtgcg gtatcggcta tgattggagt ggctttagaa
    17281 gagtctccaa ccttaaaaat ccatcacttg acgcacgata tcacgcctta taatattttt
    17341 gaggggagct atcgtctctt tcagacggtg gattactggc ctgagggaac gacgtttgta
    17401 tcggttgtcg atccaggtgt cggttcgaaa cgtaagagtg tagttgccaa gactgcaaaa
    17461 aatcaataca ttgtcacgcc agataatggg acgctttcct ttatcaagaa acacgttggc
    17521 attgtagcca ttcgtgagat ttctgaggtg gccaataggc gtcaaaacac agagcattct
    17581 tataccttcc acggtcgtga tgtctatgcc tatactggtg ctaaactggc cagtggtcac
    17641 attacttttg aggaagtagg gccagagctc agtgtggaac agattgtaga gcttccagtc
    17701 gtagcgacca tcatagaaga tcatctggtg aagggagcca ttgatattct ggatgtgcgt
    17761 ttcggttcgc tttggacctc tatcacacgg gaagaatttt acaagctgga accagaattt
    17821 ggtgatcgtt ttgaagtgac catctatcat gctgatatgc tggtctatca aaatcaggtt
    17881 gtctatggca aatcatttgc agatgtgaga attgggcaac ccatccttta catcaactct
    17941 ctctatcgtt taggtttggc tatcaaccaa ggttcctttg ccaaggccta taatgtaggt
    18001 gtcggttcat cttggaccat tgaaataaag aaaatagaag gataaaatag gagaatagta
    18061 tggaaatcaa atttacaatt aaacaagttg ttgctgtcgg aattggcgct gccctctttg
    18121 tcgtcatcgg gatgatcaac attccaaccc ctgttccaaa tacaagcatc cagcttcagt
    18181 atgcggtaca agcgctactt tctattattt ttggaccgat tatcggtttg cttgtcgggt
    18241 tgattggtca tgcaatcaag gactctcttg ctggttatgg tctatggtgg acttggatta
    18301 tcgctagcgg actctttggt ctagttgtgg gactttttag aaagtacgtt cgagtgatca
    18361 atggtgtttt tgactggaaa gatattctta tttttaacct cattcaacta cttgcaaatg
    18421 cccttgtttg gggtgtcttg gcaccacttg gagatgttgt gatttatcaa gaagcggcag
    18481 aaaaagtatt tgcacaaggg attgttgcgg gaattgccaa tggtgtatct gtagctattg
    18541 caggaactct tctcttactt gcctatgcag gaacccaaac tcgtgcagga agtttgaaaa
    18601 aggactaata ctcaatgaaa atcaaagagc aaactaggaa gctagccgca ggttgctcaa
    18661 aacagtgttt tgagattgtg gatagaactg acgaagtcag ctcaaaacat ggttttgagg
    18721 ttgtagatga aactgacgaa gtcagtaacc atacctacgg caaggcgaag ctgacgtggt
    18781 ttgaagagat tttcgaagag tataaaatga tggggaaggc tgggcaacta gtctttttcg
    18841 atgtttatag attagttagg taagtaagct aggataggaa tctttttggc gctaagattt
    18901 taagaggaga gactgcaaga agggcttgat ttatgataaa atagaagtct aagaagcgaa
    18961 tgaagagagt aagatgaaag aagctataat tgagtggaag gatttctctt tccggtatga
    19021 aacacaacaa gaaccgacct tgcaagggat agacttgacc atttacaagg gagagaaagt
    19081 cttaattgtt ggaccatctg ggtcaggtaa atctaccttg ggtcagtgtt tgaatgggat
    19141 tattcccaat atttacaagg gtcagacata tggagaattt ttgataaagg gtcaagtagc
    19201 ctttgatatg agcatctatg ataagtctca tctggttagc acagttttgc aggatacaga
    19261 tgggcagttt attggcttgt ctgtggcaga agatttggcg tttgctctgg aaaatgatgt
    19321 gacagcccta gatgagatga aaggtcgtgt ttataaatgg gctgaaaagc tggaccttct
    19381 tcctttactg gatcagcgtc ctcaggattt gtcaggtgga caaaagcagc gagtcagtct
    19441 ggctggtgtc ttgattgatg aaagtccgat tctcttgttt gatgagccac tcgccaatct
    19501 agatcccaag tcaggtcagg atattatcga attgattgac cagattcata aggaagaggg
    19561 gacgacgact ctgattatcg agcaccgttt ggaggatgtt ctgcatcgcc ctgtggatcg
    19621 gattgtcttg ataaacgatg gtcgtatcct ttttaatggg agccctgacc agttgcttgc
    19681 gactgattta ttgactcaaa atggaattcg agaacccctt tatctaacga ctctccgtca
    19741 attaggtgtg gacttagtca aggaagaaca gttagcgaat ctggataaca tgtctatctc
    19801 aaaaggtcag gttcagctgc agaatgaact ggcaaaagaa actccagaat tgcagtcact
    19861 ctttaaatta gaggacgtgt ctttctctta tgatgataga ccgattttaa aatccctaca
    19921 tttagatatt aaaaagggtg aaaagattgc tattgtcgga aaaaatggag cagggaaatc
    19981 aactctagcc aaggctataa gtagctttat tcagacggaa ggacgctatc tttgggaaaa
    20041 acaggatata aaaggcgatt ctgttgcaga gcgggcggaa cgagtaggct atgtgctaca
    20101 aaatcctaat caaatgattt caaccaatat gatttttgat gaggtggctc tagggctccg
    20161 tttgcgaggt gtggatgaga aggaaattga aacgagagtc tatgaaacct tgaaaatctg
    20221 tggactttat gaattccgta attggcctat ttctgccctg tcatttggtc agaaaaaacg
    20281 tgtcaccatt gcttcaattt tggtcttagg agctgaaatt attctcctag atgaaccgac
    20341 tgcaggtcaa gatcagaaga actatactga gattatggaa tttctcgaag agttacatca
    20401 aaaagggcat accattgtca tgattaccca tgatatgcaa ttgatgctgg attattcaga
    20461 ccgggtcctt gtcatggtgg atggagaatt gattgccgat actgttccag ccagtctgtt
    20521 gagcgatcct gagctgttag taaaagccaa tctaaaagaa acctccatct ttaacttggc
    20581 taagaaacta gatgtggatc cactggattt aacggcattt tacaaagaaa ggagagaggg
    20641 atgcaagcta aattaatcgg ttaccagcat agagatactg tgattcatcg cttgtcagga
    20701 gctgggaaac ttctcttttt cattctggta tcattggcgg ccatgattag ctatgatacc
    20761 agaatgctct tgctgattgc catcttttca gtctttctcc tctatttatc agaaattcgc
    20821 tttaaagatg tttcctttgt agccgttttt gcgacggtat ttgccgtttt aaacgttttg
    20881 atggtctatc tcttttctcc cgagtatggg gttggacttt atggagagag aagtgtgatt
    20941 tggcagggaa tcggtgtcta cactctaacc agccaggagc tcttttatct gctaaatttg
    21001 gccattaagt atctttgcac cattcctctg gctattatct ttttgatgac aacccatcct
    21061 agtcagtttg cttccagttt aaatcaaatt ggtgtgccct ataagattgc ttattctgtc
    21121 agcctgacct tgcgctatat tccagatttg caggaagaat tctttactat caagatgtct
    21181 caggaggcgc gtgggatgga attatccaag aaagcttctc ttatgcaacg aatcaaaggc
    21241 aatctgctca ttattacgcc cttgattttt agctcgctag aacgcattga taccattgcg
    21301 actgccatgg agcttcgccg ctttgggaaa gagaaaaaac gcacatggta tagttatcag
    21361 gccttgaaaa aaggagacta tattaccttg ctcttggcaa ccttgttttt agtagttagt
    21421 ttactactta tcttgcagaa tcagggacga ttttacaacc cttggaaata gcttgaaaaa
    21481 attgaaaaaa tcaagtcatt tctattgaca atgattctga aagtgttata ctaagaaagt
    21541 agtttcgctg atttacttca aacctgttgt gaggtaagtt aacgatgcct taaccacgct
    21601 gtttgctgag cttgactccg ggcagtgtgg ctattttttt gcaatggtga aaggaagcaa
    21661 gtcatgacaa atcacattgt attatttgaa cctcaaattc cacaaaatac aggcaatatc
    21721 gcgcgtactt gcgctgcgac caattctccc ctccacatca tcaagcctat gggctttcct
    21781 attgatgacc gcaagatgaa gcgggctgga ttggattact gggataagct agagatttat
    21841 ttttacgaga gtttagaaga tttcatatct cagatgaagg gaaaactcta tctgatttcg
    21901 aaattcgcgg aaaaaatcta ttctgaggtg gatttatcga ctgacgagga ccattatttt
    21961 ctctttggac gtgaagacaa gggcttacct gaagatttta tgcgagaaca tcctgagaag
    22021 gctctccgta ttcccatgaa tgatgaacat gtccgcagtc tcaatgtgtc taataccgtc
    22081 tgcatgattg tctatgaggc tcttcgccag cagaactttg caggtcttga gctcgtccat
    22141 acctatgaag tggataaatt gaaataaaaa atgaaaatga acaaaatgct tgcgcttgca
    22201 agcgtttttt gttatgataa aagagtcttc agggcagggt gtgattcccg accggcggtg
    22261 actttaacta ggaaatgatc ttttcctttt atactttgtt gacaagcttt gcctaaccag
    22321 aagttatgcc tacagcttgt cgcctagtct aaaagaaaaa tctctatttc tttctcttta
    22381 aagaagtccg cgagcgcaag ctgatgtggt gagattccac aaccgacagt atagtctgga
    22441 tgggagaaga cgaaagaata gctttgtctg ttttgataga tttatagccg gattgtaacc
    22501 acttgctttg tttttcttta atagagtaag agggaacttt tgggatataa aaagtgagaa
    22561 tagatagagg aatcctttcc aacttcttct gattttatag aaaattggag gaacctgtta
    22621 tgacaaacac acgtcgactt tcgaccattg caattctatc agccatctca tttgtgctga
    22681 tgtactttga ttttccgctt ttaccagcgg catctttcct caagatcgaa tttagtatct
    22741 tgccagtcct tgtgggtctg gtggtcatgg atttgcctgc tgctctagga gtgctcttgc
    22801 ttcgctcact cttgaagttg cttcttaaca gccaaggagt gaatacttac attggtttgc
    22861 cgatgaatat cgtagctttg ggagtttttg tcatcgtatt tgctttgatt tggaaaaagg
    22921 aacggacaac ccttcgtttc ctactaggct ctctagctgg aactattggt ttaaccttgg
    22981 ccatgttggt tctcaactat gtttatgctg ttcctttgta cgctaagttt gctaactttg
    23041 atattggaaa aattttggga ctttccaact acctaatgac catggtatta ccttttaact
    23101 tgattgaagg tgttatcttt tccgtttcat tctggttgtt gtatgttctc ttgaaaccaa
    23161 ccttaaaaca ttatgagaga taaacaaaca tttttaatga agggcagttt tgccctttta
    23221 cttttcgtta ttcttggcta catggtcaaa ttttaccctg aaacgctggt caattttgac
    23281 caatcgattc agactgccat tcgaggagac ttaccagatt atttgactat tctttttcga
    23341 gccctcacac gtctgattga tatcccagtg attatcactt gggttgtcat tacagctttt
    23401 gtcttttatc gtaagcgatg gaagatagaa agtttcttca tgctgggaaa tctggctttg
    23461 gcaggtcttt taatcgtgac ctttaaaaat atctaccagc gcccacggcc agatatctta
    23521 catctggtgg aggagaaggg attttccttc ccaagtgggc attctctggc tgtaaccttg
    23581 atggtaggta ctttgattgt tattcttagt cagcggatta aagatccagt ctggagaaaa
    23641 atcgtacaaa tcgtccttgg cctctaccta gtcagtgtgc tggtatcaag agtctatctg
    23701 ggagttcatt acccatcaga cgtccttgcc agtctctgtg tgggcttggg agtcctgttt
    23761 atcgagtttc ccttctatga caagctccgc ttccaatggc gatttaaagg caaacagaag
    23821 tgagtatcga attcccttga ggagaaagaa atgaaagtca acatagcaga tcttcatccg
    23881 actcaactat atttatcaga aaagaagttg caagatattc agatgcttta ccagtcggca
    23941 gaaacaatcc aagtcgatcc aatcagtatt cttgcctttg gagattgttt gctgattaca
    24001 gatgggcatc acagggctta tcagacttta ttggcagatc gggatacgat ttctgctgag
    24061 tgggatagag atggtggtga tgaactatat catctctatg cgcaagcttg cgaggaaaga
    24121 aagatttact ctgtttttga tttagaagat cgtatcctag ctcaagatgg gtatgaagca
    24181 aaatggtata actggtgtga tggttttaat caagcagcaa ctcttttgtt gaaaaggtag
    24241 tgcattgtgt tttgttcctt attataaggt caatcattgt gaggaagctt ttgcttggta
    24301 tcaggatgtg aacttggttt acctcgtaga tggggtgaag cttccttaca gtcaagcgac
    24361 cttggaagcc atgtattcct atttggatcg gcatggtgag cttttttgga ttgaagtcaa
    24421 ggagaaggga gaatggtttc caattgggga tattacacta tctcaggata atctccccat
    24481 tgtgattggg aattccgctt accaacatcg aggacttgga aaaaagattc taagtgcttt
    24541 gattgaattg gctcgagtaa aaggatggaa agaattgaga gtcaaggaaa tctacaccta
    24601 caatcatgct tctaggaggt gtttcaagtc gcttggattt gtggaaaatg gagcaacaga
    24661 aaaaggaatg agttttatat tggaattagt ctaatcctgc cattttctcc cccttaacct
    24721 ttgactattc tgcaaaatta tcgtaaaata aagagtaaat gataaaatga ggtcagagtc
    24781 tgttcgctct ggcgatagta gtataaatga ggagaaacgc tttggaatta gaagtatttg
    24841 ctgggcaaga aaaaagtgaa ctatctatga ttgaggtagc gcgtgctatc ttggaacttc
    24901 gtggtcgcga tcatgagatg cattttagcg atcttgtaaa cgaaattcaa aactaccttg
    24961 gaacatcaaa cagcgatatc cgcgaagctt tgcctttgtt ctacacagag ttgaactttg
    25021 acggtagctt catctcactt ggggacaaca aatggggtct tcgttcatgg tatggtgtgg
    25081 acgaaatcga cgaagaaatc atcgctcttg aagaaaatga cgacgatgaa gtagcaccaa
    25141 aagctaagaa aaaacgtgtc aatgccttta tggatggtga ttcagatgcc attgactaca
    25201 atgcagatga tccagaagac gaagatgcat acgaagcaga tccagctctt tcatacgatg
    25261 atgaaaatcc agatgatgaa aaaaatgaag tggaagctta tgatgcagaa atcaacgaaa
    25321 tcgctccaga tgacttggga gaagatgtgg atctcaacga agacgacgac gagttttcag
    25381 atgacgacgc tgaaaccagc gaggaataag agttagctat tgacaattat cctattttta
    25441 ggtatcatat tgtttgggca cctcttttag aggtcggggc tccctagttc ttagggagct
    25501 atttttgttt tttcaagaag ttatcttctt gtattttata ctcaatgaaa atcaaagagc
    25561 aagctaggaa actagccgta ggctgctcaa aacactattt tgaggttgta gataagactg
    25621 acaaagtcag gaacacatat ctacggcaag gcgacgttga cgcggtttga agagtattag
    25681 ctgtgaatct ggtgcagtcg tcccagatta ttcttattag tagggtcttg ttttctatat
    25741 cccctcgtag ttaacaagac cttgagcatt ttagaaagag gaatctatgt ctacgaaata
    25801 tatttttgta actggtggtg tggtatcgtc tattgggaaa gggattgtgg cagcgagtct
    25861 aggccgtctc ttgaaaaatc gtggtctcaa agtaaccatt caaaagtttg acccttatat
    25921 caatattgat ccgggaacca tgagtcctta ccagcacggg gaagtttttg tgacagatga
    25981 cggagctgag acagatttgg acttgggtca ctatgaacgt ttcatcgata tcaatctcaa
    26041 caaatattcc aacgtgacaa ctgggaaaat ttacagtgaa gttcttcgta aagaacgccg
    26101 tggagaatac cttggggcaa ctgttcaagt cattcctcat atcacagatg ctttgaaaga
    26161 aaaaatcaag cgtgccgctc taacgaccga ctctgatgtc attatcacag aggttggtgg
    26221 aacagtagga gatatcgagt ccttgccatt cctagaggct cttcgtcaga tgaaggcaga
    26281 tgtgggtgcg gataatgtca tgtatatcca tacaaccttg cttccttacc tcaaggctgc
    26341 tggtgaaatg aaaaccaaac caacccaaca ctctgtcaaa gaattgcgtg gcttgggaat
    26401 ccaaccaaat atgttggtta ttcgtacaga agagccagct ggtcaaggaa ttaaaaataa
    26461 actggcccag ttctgtgatg tggcaccaga agccgttatc gaatcgttgg atgttgaaca
    26521 cctttaccaa attccactga acttgcaggc acaagggatg gaccaaattg tttgtgatca
    26581 tttgaaatta gacgcaccag cagcggatat gacagaatgg tcagccatgg tggacaaggt
    26641 catgaacctc aagaaacaag ttaagatttc ccttgttggt aagtatgtgg agttgcaaga
    26701 tgcctatatc tcagtggtcg aagccttgaa acactctggc tatgtcaatg atgtagaagt
    26761 taaaatcaat tgggtcaatg ccaatgatgt gacagcagag aatgtagcag aactcttgtc
    26821 tgatgcggac gggatcatcg taccaggtgg ttttggtcaa cgtggtacag aagggaaaat
    26881 ccaagccatc cgctatgcgc gtgaaaatga tgttccaatg ttgggagtct gcttgggaat
    26941 gcagttgaca tgtatcgagt ttgctcgtca cgttttaggt cttgaaggtg ccaattctgc
    27001 agagcttgca ccagaaacaa aataccctat cattgatatc atgcgtgatc agattgatat
    27061 tgaggatatg ggtggaaccc ttcgtttggg actttatccg tctaagttga aacgtggctc
    27121 taaggctgct gctgcttatc acaatcaaga agtggtgcaa cgccgtcacc gtcaccgtta
    27181 tgagtttaat aatgccttcc gtgagcagtt tgaggcagca ggttttgtct tttcaggagt
    27241 ttctccagac aatcgtttgg tagaaatcgt ggaaattcct gaaaataaat tctttgtagc
    27301 ttgtcagtat catcctgaac tgtcaagccg tccaaaccga ccagaagaac tctacactgc
    27361 ctttgttact gcagcggttg agaacagcaa ttagcaaaat cagaaccttt gagaaaaatc
    27421 tcagaggttt tttgcatacg atgatattgc agtatatctg aggtaggagt cctctgtatg
    27481 tacctgctac cgttgaaatc aatagcgact ccctcttgcc ctgtgctagt gaatggattt
    27541 atcagtatat tgaaatgaaa taaaatttga acaaattaat tcggaaagcc aaatcaattt
    27601 ctagcaaagt tttaggaact ggattgtata gtgaattgaa ataagatgtg aacatctcta
    27661 tcaggaaagt caaattaatt tatagaaata ttttagcagt caaagtgtac tgttatagat
    27721 tcaatacact atagaataga attgtaggtt ttaaaaacgc ttacattgtt ttaaaataaa
    27781 cttaaataac acaacggagg tatccatcat gaaaaagaaa tggatgtatt atgctgcttg
    27841 ttcttctaat gaatctgccg atgacagttc atctgataaa ggagacggtg gttcgctagt
    27901 cgtttattga ccaaactcag aaggcttaat tggagcaact attcctgcct ttgaagaaaa
    27961 atatggtatc aaaatagaac tgattcaagc tggtactgga gaacttttca aaaaactaga
    28021 gtcagaaaaa gaagttcctg tagctgatgt tatctttggt ggttcttata cacaatatgc
    28081 tacccacgga gaactctttg aaaactatat ttcaaaagaa aatgataatg ttatcaaaga
    28141 atatcaaaac acaactggct tctctactcc ttatacacta gatggtagtg ttttaatcgt
    28201 ccaccctgat ttaactaaag gcatgaacat cgaaggatat agcgaccttc tcaaacctga
    28261 actaaaagga aaaatcgcaa ctgctgaccc agcaaactct tctagcgcct ttgctcaatt
    28321 aacaaatatg ctacaagctc aaggtggtta caaagatgat aaggcttggt cttatgtaaa
    28381 agatcttttc acacttattg atggtatagt aaaatgaaat aagaacagga caaattaatc
    28441 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtgtacta ttctagtttc
    28501 aatacactat aaaatcggtt taagttcatc tggtgtctat aaagcagtcg ttgatggaga
    28561 aatggctgtt ggtctctctt atgaggatcc agcagttaaa ctcttaaatg acggagctaa
    28621 cattaaagta gtctatccaa aagaaggaac cgtcttccta cctgctagtg ctgctatcgt
    28681 taaaaaagct aaaaatatgg aaaatgccaa gaaatttatc gattttatta tctctcaaga
    28741 agtacaagat acacttggta caaccactac taaccgtcct gttcgtaaaa atgctaaaac
    28801 aagcgaaaac atgaaaccaa ttgacaaaat caaaacactc actgaagatt atgattatgt
    28861 catcaagaat aaatcagata tcgttaagaa atacaacgaa gtctttacag atatccaatc
    28921 taaacagtaa aagaggttca ctatgagtga gatcgaaatt attaacgcca aaaaaatcta
    28981 ccacgatgtc cctgttattg agaatttgaa cattacaatt ccaaaaggaa gtctctttac
    29041 ccttcttgga gcttcaggat gtgggaaaac gacccttctt cgtatgattg caggtttcaa
    29101 cagtatcaaa gatggagaat tttacttcga tgatacaaaa atcaataata tggaacccag
    29161 caaacgcaat atcgggctgg ttttccaaaa ctacgctatt ttcccacatt tgactgtccg
    29221 agacaacgtt gcttttggtc ttatgcaaaa gaaggttcca aaagaagaat tgattcaaca
    29281 gaccaacaag tatcttgaac tcatgcaaat tgctcaatat gcggattgaa agcccgataa
    29341 actcagtggt ggacaacaac aacgtgtcac cttggcatgc gccttagcgg ttaatccaag
    29401 tgttctcctc atggacgagc cacttagtaa tctggaggcc aaacttcgct tggatatgcg
    29461 tcaagccatc cgagcaatcc aacacgaagt gggaattaca actgtttatg taacccacga
    29521 ccaagaagaa gccatggcta tttcagacca aattgctgct atgaaagatg gggtgatcca
    29581 acaaatcggc cgaccaaaag aactctatca taaaccagct aatgagtttg tggcaacctt
    29641 tatcggatgc acaaatatta tccctactaa tcttgaaaaa cggagcgacg gcgcttatat
    29701 cgtcttttca gatggctatg cccttcgaat gccagctctt gatcaggttg aggagcaagc
    29761 tattcatgta agcattcgtc ccgaagagtt tatcaaagat gaatctggag atattgaagg
    29821 aactattagc gatagcgtct atcttggact aaatacggag tatttcattg agacaggttt
    29881 tgcctcaaaa attcaagtta gtgaagaatc aacttttgaa gaagaactac aaaaaggcaa
    29941 tcgtattcgt ctacgaatca atacgcaaaa attaaacatc ttttctgcag atggttccca
    30001 aaacctgata aaaggagtca accatggaat gtaaaaaact aaatatttgg acaacctcct
    30061 ctttcttcat ctttcttacc tatcttgtct ttctcgttta tcctatcgtt accgtgctca
    30121 agcaagcact tatacatgaa ggacaattct cactagctaa ttttgtcact ttctttagta
    30181 aagtctacta ctctgagaca ctagtcaaca gtttcaaggt ttccattacc gctactgtca
    30241 cttccttagt tgtaggaacc ctattagctt atctcttctc tatgtatgac ttcaagggga
    30301 agaaatttct acaaatattg attatcattg cttccatgtc agctcctttc gtaggagcct
    30361 actcctgggt tctcttgcta ggacgaaatg gggtcatcac taaatttttg acaaatgccc
    30421 ttcatcttcc agctatcgat atttatggat tcaaaggaat tgtacttgtc tttacactgc
    30481 aactattccc actggtattt ctatatgttg ctggaacaat gaacagtatt gacaattctc
    30541 tacttgaagc agctgaaagc atggggtcct tcggatttaa acctatcgta acggttgttt
    30601 tacctctcct agttccaacc ttactagcag ctccttgctt gtatttatga gagcattctc
    30661 agactttgga acgcctatgt tgattggcga aggatatcgg actttccctg tcctgattta
    30721 tacccaattt attagcgagg ttggaggaaa ttctgctttt gcaattatgg cgattatcat
    30781 tgccttggca attttcctta tccaaaaaca cattgcaaac cgctacagtt tcagcatgaa
    30841 tctgctccat ccaattgagc ctaaaaaaac tacaaaagga aaaatggctg ccatttatgc
    30901 aacagtctac ggaattatct ttatctctgt tttacctcaa atctacttaa tttatacctc
    30961 tttcctaaaa acatcaggta tggtatttgt taaaggttat tctccaaaca gttacaaggt
    31021 agctttcaat cgtatgggat ctgctatttt caataccatt cgtatccctt tgattgcctt
    31081 agttctagtt gttctatttg cgacatttat ctcctaccta gccgttagaa aacggaattt
    31141 gtttacaaac ttaattgaca gcctcagtat ggtaccttat attgtaccag gaaccgttct
    31201 agggattgcc ttcatttctc tggtctattt ggaagtggat ttcttatgat tacagggact
    31261 gctttcatct tgattatgtc tctatctgtc agaagattac cgtatactat tcgctcatct
    31321 gttgctagct tacaacaaat agcaccaagt attgaagaag ctgctgaaag cttaggaagt
    31381 agtcgtctca atacctttgc taagattaca actccaatga tgctatctgg tatcatttct
    31441 ggagccatct tatcttgggt cacaatgatt tcaaaactct ctacttctat cctcctctac
    31501 aatgtcaaaa caagaacaat gactgtagct atttatacag aggttctcag aggaaattac
    31561 ggtgtagccg cagccttgtc aactatcctg actgttctaa cagtaggttc cttgctcttg
    31621 tttatgaaaa tctctaaaag caatagcatt acactttagt tttccacatc aaaaacagcc
    31681 gaaaggagta ccctcggctg ttttttctta tcttgatatc cttatcaaat ccctagctca
    31741 tggcaagcaa gtctagactg attaaataga gccttcttcc atcttctcac gtcctagctc
    31801 tcggtaacta cggtcaccga caacttcaac cctaaactga ccgtcctcat attcaagaat
    31861 cgtcacgcta ccattatcta gaccatgcgg atgcatgcca ttaatcagat aaacaatggt
    31921 tccaatagtc attccatggc tgacaacaag ggcgttacct ccaccttgat cttccatttc
    31981 ttttgcaatt atttcaaagc cttccttgat tcggccactg agtttttccc agccttcagc
    32041 ccaaccagct gtatcgacct ctaccaagcc ctcagccagt tcagcataag acaattggtg
    32101 aacgtggtcc acattaaaga tacgaggaat aatgcccatg aaaagatcgc catcataggc
    32161 tccatcaaaa ctaccgaaac accattctct gatacgcttg tccatgcgat aagggatttt
    32221 cccctgcaag ccaagctctt caaggataat tcccatggtc tgaatggtac gaccagaatc
    32281 actcgaataa gcgcgctcaa actgtagatc agattctcgc aaaccgattc ctaactcttg
    32341 aatccctcgt tcaccttcag cagttaaggg agtatcgctc caaccttgcg cgcgaccaat
    32401 cgtgttaaac atggtcttgc catgacgtac caaatacaat cgtactttta ccattttccg
    32461 tcctccgttt gcttctatta tatcatgaat gataaaataa aagccaccca tacaggcgac
    32521 ttttgaagga gattattatg aaaaagttta ggagttcatt aaataaagat attagatgaa
    32581 aatcaaattc aaactaattc ag
//
LOCUS       DAVLMQ010000019        31708 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000019 DAVLMQ010000000
VERSION     DAVLMQ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.019"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(428..520)
                     /locus_tag="VXF95_001084"
     CDS             complement(428..520)
                     /locus_tag="VXF95_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HEV1081646.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            681..1652
                     /gene="ruvB"
                     /locus_tag="VXF95_001085"
     CDS             681..1652
                     /gene="ruvB"
                     /locus_tag="VXF95_001085"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HEV1081647.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            1741..2205
                     /locus_tag="VXF95_001086"
     CDS             1741..2205
                     /locus_tag="VXF95_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HEV1081648.1"
                     /translation="MAAGSVRNFIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLE
                     KKLREDFPQYQWELKNQVYMHQHSPHTASYTSSRDAMSKYPERCTAVGLRLNEESDFE
                     LYAPYGLEDILNFQVRPTPHFLENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            2436..3194
                     /locus_tag="VXF95_001087"
     CDS             2436..3194
                     /locus_tag="VXF95_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HEV1081649.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            3203..4006
                     /locus_tag="VXF95_001088"
     CDS             3203..4006
                     /locus_tag="VXF95_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HEV1081650.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLVMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            4028..5287
                     /gene="rseP"
                     /locus_tag="VXF95_001089"
     CDS             4028..5287
                     /gene="rseP"
                     /locus_tag="VXF95_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HEV1081651.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            5300..7153
                     /locus_tag="VXF95_001090"
     CDS             5300..7153
                     /locus_tag="VXF95_001090"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HEV1081652.1"
                     /translation="MKQSKMPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTAEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            7253..8632
                     /gene="bglA"
                     /locus_tag="VXF95_001091"
     CDS             7253..8632
                     /gene="bglA"
                     /locus_tag="VXF95_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HEV1081653.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTVFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGICLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KKLSDNNGF"
     gene            8824..10632
                     /gene="glmS"
                     /locus_tag="VXF95_001092"
     CDS             8824..10632
                     /gene="glmS"
                     /locus_tag="VXF95_001092"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HEV1081654.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDDAGQ
                     VVVDPAIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLIHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            10751..11800
                     /locus_tag="VXF95_001093"
     CDS             10751..11800
                     /locus_tag="VXF95_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HEV1081655.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIDGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLDQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(11900..15697)
                     /gene="spuA"
                     /locus_tag="VXF95_001094"
     CDS             complement(11900..15697)
                     /gene="spuA"
                     /locus_tag="VXF95_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HEV1081656.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVEIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSIPSK
                     PEHQNEASHPAYQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSV
                     KEAVQNESVENSSKKNIPATPDRQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNK
                     KEN"
     gene            16114..16527
                     /gene="rpsL"
                     /locus_tag="VXF95_001095"
     CDS             16114..16527
                     /gene="rpsL"
                     /locus_tag="VXF95_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HEV1081657.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            16547..17017
                     /gene="rpsG"
                     /locus_tag="VXF95_001096"
     CDS             16547..17017
                     /gene="rpsG"
                     /locus_tag="VXF95_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HEV1081658.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            17442..19523
                     /gene="fusA"
                     /locus_tag="VXF95_001097"
     CDS             17442..19523
                     /gene="fusA"
                     /locus_tag="VXF95_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HEV1081659.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLIEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIDTVYSGDIAAAVGLKDTTTGDSLTDEK
                     SKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLSLKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            19627..24018
                     /locus_tag="VXF95_001098"
     CDS             19627..24018
                     /locus_tag="VXF95_001098"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HEV1081660.1"
                     /translation="MSNSFEILMNQLGMPAEMRQAPALAQANIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKARSQEFSNQLLQSYYREAFSEGP
                     CASQGFKFLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEEAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPVFDFQAKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDLQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVEMDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGHPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHDLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDVVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKSLIEVGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPHKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNKIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNGYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            24120..24383
                     /locus_tag="VXF95_001099"
     CDS             24120..24383
                     /locus_tag="VXF95_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HEV1081661.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            24376..24654
                     /locus_tag="VXF95_001100"
     CDS             24376..24654
                     /locus_tag="VXF95_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HEV1081662.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            24675..24827
                     /locus_tag="VXF95_001101"
     CDS             24675..24827
                     /locus_tag="VXF95_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081663.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALKEK"
     gene            24849..26090
                     /locus_tag="VXF95_001102"
     CDS             24849..26090
                     /locus_tag="VXF95_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HEV1081664.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     IFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            26100..26330
                     /locus_tag="VXF95_001103"
     CDS             26100..26330
                     /locus_tag="VXF95_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1081665.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
     gene            26553..27275
                     /locus_tag="VXF95_001104"
     CDS             26553..27275
                     /locus_tag="VXF95_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HEV1081666.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            27492..28826
                     /gene="pepC"
                     /locus_tag="VXF95_001105"
     CDS             27492..28826
                     /gene="pepC"
                     /locus_tag="VXF95_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HEV1081667.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSH
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAILNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAK"
     gene            complement(28882..29793)
                     /locus_tag="VXF95_001106"
     CDS             complement(28882..29793)
                     /locus_tag="VXF95_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1081668.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(29817..30620)
                     /locus_tag="VXF95_001107"
     CDS             complement(29817..30620)
                     /locus_tag="VXF95_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HEV1081669.1"
                     /translation="MSIISMVLVIVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(30648..31637)
                     /gene="manX"
                     /locus_tag="VXF95_001108"
     CDS             complement(30648..31637)
                     /gene="manX"
                     /locus_tag="VXF95_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HEV1081670.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
BASE COUNT         9020 a         6116 c         7420 g         9152 t
ORIGIN      
        1 atttttcggt atttttcgga ttttggtcgg ggaattggcg gggacttttt tagcgaatat
       61 aactaagaaa taggtctgtg gtcgcttcag ctagttcaaa ctcaatttga ttgtaagtga
      121 ctgttaattg aagaactgga actactgtaa taatgatttt gcttgtctag tagtggcgta
      181 ttaaatgaga agtgacatgt aagattgtct cttcgtttac gaaatcaaaa tttctatgaa
      241 attgatagaa tccctaacgt tctcttaatc ttaaccgtct tgtcgtacag cggttgaaga
      301 aaatgtaaac ctttgacaaa attcgtgaac tatgggataa taaaaaggaa ttgagtacta
      361 gttctatatc ataggctaga aaagacccca agctcacgac caaataagct tggggtcttt
      421 tttgacacta tttgtccttg tttagccatt tatcgactat acgaagaacg acaccgacca
      481 caattggtcc gatgatagtt ttgagtacta attccatcat gggctatctc acctcctttc
      541 gtaggcggtg tagcagtgtc gtagaatatt ataccacata agtgctaaac ttaggagtca
      601 cccaatcagg tggctttttt gtttgtggct tggttttttg atataataga gccatgagta
      661 gaattttaga taatgagata atgggggatg aggagttagt agaacgcacg ctccgtcctc
      721 agtatttacg tgaatatatt gggcaggata aggttaagga ccagcttcaa atctttatag
      781 aagctgccaa aatgcgagat gaagcgctgg atcatgtcct cttatttggg cctccaggtt
      841 tggggaaaac aaccatggct tttgtcattg ccaatgaact gggagtcaat ctcaagcaaa
      901 cgtctggtcc tgttatcgaa aaagcgggtg atttggtagc gattttgaat gagttagagc
      961 ctggagatgt cctctttatt gacgagattc atcgcttacc catgtcagtg gaagaagtgc
     1021 tttatagtgc catggaggac ttctacatcg atattatgat tggggctggt gaaggcagtc
     1081 gcagtgttca tttggagttg cctcctttta ccttgattgg tgcgacgact cgggctggta
     1141 tgctctcaaa tccactacgg gcacgttttg ggattacagg tcatatggag tattatgccc
     1201 atgctgactt gacagaaatt gtcgagcgga cggcagatat ttttgagatg gaaatcactc
     1261 atgaggcagc atctgagttg gccctacgta gtcgtggaac ccctcgtatt gccaatcgtc
     1321 tcctcaagcg cgtgcgcgat tttgcccaga taatggggaa tggggtaatc gatgatatta
     1381 ttaccgataa ggctttgact atgctggatg ttgaccatga aggtttggac tatgtggatc
     1441 aaaaaatcct tcgtaccatg attgagatgt acagtggagg acctgttggt ctaggaactc
     1501 tttctgtcaa tatcgccgaa gagcgtgaga cagttgaaga catgtatgag ccttacttga
     1561 ttcaaaaagg ttttatcatg cggacacggt ctggacgggt ggcgactgct aaggcatatg
     1621 agcacttagg ttatgaatac agtgaaaaat aagcaagaaa tcttagaggc ttttagagaa
     1681 aatccagata tgatggccat tctgacgatc atccgagacc ttggtttgaa agactcgtag
     1741 ttggcagcag gttctgtcag aaatttcatc tggaatcttt tgtcagacaa atcccctttt
     1801 gatcatgaaa cagatataga tgtgattttc tttgatccag atttttctta tgaggaaacc
     1861 ttattactgg agaaaaagct gagagaggat tttcctcagt accagtggga attgaaaaat
     1921 caggtctata tgcatcagca cagtcctcac actgcttcct ataccagttc tcgtgatgct
     1981 atgagtaagt atccagaacg gtgtacggca gttggactgc gcttgaatga agaatcagat
     2041 tttgaactct atgcacctta tggtttggag gatattttga attttcaagt tcgtccaact
     2101 cctcatttct tagaaaatga agaccgaatg gaactctatc aaacacgttt atccaagaaa
     2161 aattggcagg agaaatggaa aaatttgatt tttaaaaata cttaaggaaa ctttaagcta
     2221 gggagtgtac actaagttca taagttaaga agaccttaac ttaaactcct aaaacttttt
     2281 cataataatc tccctataaa aataaagtcg cccaatcagg cggcttattt ttttgaaaaa
     2341 tgggcatggt gcctgagaat aaatagctta gtgatagaag aaaatgggga aatatggtat
     2401 aatgaaacga tagatttttg aataggaata agatcatgtt tggatttttt aagaaagata
     2461 aggctgtgga agtagaggtt ccgacacagg ttcctgctca tatcggcatc atcatggatg
     2521 gcaatggccg ttgggctaaa aaacgtatgc aaccgcgagt ttttggacat aaggcgggca
     2581 tggaagcatt gcaaaccgtg accaaggcag ccaacaaact gggcgtcaag gttattacgg
     2641 tctatgcttt ttctacggaa aactggaccc gtccagatca ggaagtcaag tttatcatga
     2701 acttgccagt agagttttat gataattatg tcccggaact acatgcgaat aatgttaaga
     2761 ttcaaatgat tggggagaca gaccgcctgc ctaagcaaac ctttgaagct ttaaccaagg
     2821 ctgaggaatt gactaagaac aacacaggat tgattcttaa ttttgctctt aactatggtg
     2881 gacgtgctga gattacacag gcgcttaagt tgatttccca ggatgtttta gatgccaaaa
     2941 tcaacccagg tgacatcaca gaggaattga ttggtaacta tctctttact cagcatttgc
     3001 ctaaggactt acgagaccca gacttgatta tccgtactag tggagaatta cgtttgagca
     3061 atttccttcc atggcaggga gcctatagtg agctttattt tacggacacc ttatggcctg
     3121 attttgacga agcggccttg caggaagcta ttcttgccta taatcgtcgt catcgccgat
     3181 ttggaggagt ttaggaggaa atatgaccca ggatttacag aaaagaacct tgtttgcagg
     3241 gattgccctg gctattttcc taccaatttt aatgattggg ggcctcttgc ttcagatagc
     3301 aatcggaatc atagccatgc tagtcatgca tgaacttttg aagatgagag gtctagagac
     3361 catgacgatg gagggcctct tgaccctctt tgcaaccttt gcattgacca ttcccttgga
     3421 gaattacctg acttttttgc cagttgatgg gaatgtggtt gcctatagtg ttttgatttc
     3481 aatcatgtta ggaacgaccg tttttagcaa gtcttatacg attgaggatg cggttttccc
     3541 tcttgctatg agcttctacg tgggctttgg atttaatgct ttactagatg ctcgtgttgc
     3601 aggtttggac aaggctctct tagccttgtg tatcgtctgg gcgacagaca gtggtgccta
     3661 tcttgttggg atgaactatg ggaaacgaaa gttagcacca agggtatcgc ctaataaaac
     3721 ccttgagggt gccttgggtg gtattttagg agcaatttta gtaaccatta tctttatgat
     3781 agttgacagt acagttgctc ttccatatgg aatttacaag atgtcagtct ttgctatttt
     3841 ctttagcatt gctggacaat ttggtgattt actagaaagt tcgatcaaac gtcattttgg
     3901 tgttaaggat tctgggaaat ttatccctgg acatggtggt gttttggatc gtttcgatag
     3961 tatgttgctt gtatttccaa tcatgcactt atttggactc ttttaatcaa aagacggagg
     4021 aaacgctatg ctcggaattt taacctttat tctggttttc gggattattg tagtggtgca
     4081 cgagttcggg cacttctact ttgccaagaa atcagggatt ttagtacgtg aatttgccat
     4141 cggtatggga cctaaaattt ttgctcacat tggtaaggat ggaacggcct ataccattcg
     4201 aattttgcct ctgggtggct atgtccgcat ggccggttgg ggtgatgata caactgaaat
     4261 caagacagga acgcctgtta gtttgacact tgctgatgat ggtaaggtta aacgcatcaa
     4321 tctctcaggt aaaaaattgg atcaaacagc cctccctatg caggtgaccc agtttgattt
     4381 tgaagacaag ctctttatca aaggattggt tctggaagaa gaaaaaacat ttgcagtgga
     4441 tcacgatgca acggttgtgg aagcagatgg tactgaggtt cggattgcac ctttagatgt
     4501 tcaatatcaa aatgcgacta tctggggcaa actgattacc aattttgcag gtcctatgaa
     4561 caattttatc ttaggtgtcg ttgttttttg ggttttaatc tttatgcagg gtggtgtcag
     4621 agatgttgat accaatcagt tccatatcat gccccaaggt gccttggcca aggtaggagt
     4681 accagaaacg gcacaaatta ccaagattgg ctcacatgag gttagcaact gggaaagctt
     4741 gatccaagct gtggaaacag aaaccaaaga taagacggca ccgactttgg atgtgactat
     4801 ttctgaaaag gggagtgaca aacaagtcac tgttacaccc gaagatagtc aaggtcgtta
     4861 ccttctaggt gttcaaccgg gggttaagtc agattttcta tccatgtttg taggtggttt
     4921 tacaactgct gctgactcag ctctccgaat tctctcagct ctgaaaaatc tgattttcca
     4981 accggatttg aacaagttgg gtggacctgt tgctatcttt aaggcaagta gtgatgctgc
     5041 taaaaatgga attgaaaata tcttgtactt cttggcaatg atttccatca atattgggat
     5101 ttttaatctt attccgattc cagccttgga tggtggtaag attgtgctca atatcctaga
     5161 agccatccgc cgcaaaccat tgaaacaaga aattgaaacc tatgtcacct tggccggagt
     5221 ggtcatcatg gttgtcttga tgattgctgt gacttggaat gacattatgc gactcttttt
     5281 tagataatcg aggaatatta tgaaacaaag taaaatgcct atcccaacgc ttcgcgaaat
     5341 gccaagcgat gctcaagtta tcagccatgc tcttatgttg cgtgctggtt atgttcgcca
     5401 agtttcagca ggtgtttatt cttatctacc acttgccaac cgtgtgattg aaaaagctaa
     5461 aaacatcatg cgccaagaat tcgaaaagat tggtgctgtt gagatgttgg ctccagccct
     5521 tcttagtgca gaattgtggc gtgaatcagg tcgttacgaa acctatggtg aagaccttta
     5581 caaactgaaa aaccgtgaaa aatcagactt tatcttaggt ccaactcacg aagaaacctt
     5641 tacagctatt gtccgtgatt ctgttaaatc ttacaagcaa ttgccactca acctttatca
     5701 aattcagccc aagtatcgtg atgaaaaacg cccacgtaat ggacttcttc gtacacgtga
     5761 gtttatcatg aaggatgctt atagtttcca cgctaactat gatagtttgg atagtgttta
     5821 tgatgagtac aaagcagcct atgagcgtat tttcactcgt agtggtttag acttcaaggc
     5881 tattattggt gacggtggag ccatgggtgg taaggatagc caagaattta tggccattac
     5941 atctgctcgt acagaccttg accgctgggt tgtcttggac aagtcagttg cctcatttga
     6001 cgaaattcct gcagaagtgc aagaagaaat caaggcagaa ttgctcaaat ggatagtctc
     6061 tggtgaagat accattgctt actcaagtga gtctagctat gcagctaact tagaaatggc
     6121 aacaaacgag tacaaaccaa gcaaccgtgt tgtcgctgaa gaagaagtta ctcgtgttgc
     6181 aacgccagat gttaaatcaa ttgatgaagt tgcagctttc ctcaatgttc cagaagaaca
     6241 aacgattaaa accctcttct acattgcaga tggtgagctt gttgcagccc ttctagttgg
     6301 aaatgaccaa ctcaacgaag tcaagttgaa aaaccacttg ggagcagatt tctttgacgt
     6361 tgctagcgaa gaagaagtgg cgaatgttgt tcaagcagga tttggttcac ttggaccagt
     6421 tggtttgcca gagaatatta aaattattgc agatcgtaag gtgcaagatg ttcgcaatgc
     6481 agttgtcggt gctaacgaag atggctacca cttgactggt gtgaacccag gccgtgattt
     6541 tactgcagaa tatgtggata tccgtgaagt tcgtgagggt gaaatttccc cagatggaca
     6601 aggtgtcctt aactttgcgc gtggtattga gatcggtcat attttcaaac tcggaactcg
     6661 ctactcagca agcatgggag cagatgtctt ggatgaaaat ggtcgtgctg tgccaatcat
     6721 catgggatgt tacggtatcg gtgtcagccg tcttctttca gcagtgatgg agcaacacgc
     6781 tcgcctcttt gttaacaaaa cgccaaaagg tgaataccgt tacgcttggg gaatcaattt
     6841 ccctaaagaa ttggcaccat ttgatgtgca tttgattact gtcaatgtca aggatgaaga
     6901 agcgcaagcc ttgacagaaa aacttgaagc aagcttgatg ggagctggtt atgaagtctt
     6961 gacagatgac cgtaacgaac gtgtcggtgt taaatttagc gatagtgact tgattggtct
     7021 tccaatccgt atcactgttg gtaaaaaagc ggccgatggc attgtagaag ttaagatcaa
     7081 ggcaactggt gacaccattg aggttcatgc agataacgtg cttgaaacgc ttgaaatcct
     7141 aagcaagaaa taaaaactat aatcagaaga aaaacaagga aaaaatgtaa ctagttttta
     7201 ccttgttttt tctgtataat gggagaaatg agtagataaa gaggtaaatg ttatgctaag
     7261 atttccaaag gattttgtct ggggatcctc tacttctgga ccgcagacag aaggacgtgt
     7321 agctggtgac ggtaagggag acaatctctg ggattactgg ttccaagtgg agccaaatcg
     7381 ttactataat gggattggtt cagataagac atcgactttt tatgaaaatt gggagcggga
     7441 tattgagctt ttgttagaga ctggtcacac agtctttcgg acttctattc agtggtcacg
     7501 gatttttcca caaggctgtg gaaaagtcaa ccctcaaggt gtggattttt atcgtaaggt
     7561 ctttgaggct attaaggcta aaggaatttg tctgttagtc aatctctatc attttgattt
     7621 accttttgcc cttcaagagg atggtgatgg ttgggaaaat aaggcgacag tctcagccta
     7681 tgaagactat gctcgttttt gttttgagac ttatggagat ttagtggatc aatggattac
     7741 ctttaacgag cccatcgttc ctgtagaatt tggttatttt tatgatgccc attatccaca
     7801 taaggtggat gcagaggcag ctgttaaggt agcctatcat acacaattgg ccagcagccg
     7861 ggctgttaag gcttgccatg aacttttgcc tgattccaag attgggattg tcctcaactt
     7921 gacaccggct tatccacgta gccagcatcc tgctgatgtc aaggcagctc gtattgcggc
     7981 cctttttcag gcccaatctt tcttagatcc atctgtcttg gggacttatc cacaggagtt
     8041 ggtagaaatc ttgcatgaac acggtctttt acctgatgct acagaggaag agttggaact
     8101 cattcgtgat aatacggtgg acttccttgg tgtgaactac tatcaacctt tgcgtgttat
     8161 ggctcctcga tttgctaagc atccagagag tccactctta ccagaacatt tttacgagcc
     8221 ttatgtgatg cctggacgta aaatcaattc tcatcgtggt tgggagattt atgagcaagg
     8281 gatttatgac atcgcccaaa atatcaagga aaattatggc aatattgagt ggatgttgac
     8341 tgagaatggt atgggtgttg aaggggaaga aaaattccgt caagatggaa tgattcaaga
     8401 tgattaccgt attgactttg taaaaggtca tcttcgtgaa cttcaccgtg ccattgaaga
     8461 tggtgccaac tgtaagggct acttgatttg gacctttatt gactgctggt catggctcaa
     8521 cagctataaa aatcgctatg gtttggtcga attagacttg gaaacgcaag aacgtcgtct
     8581 gaagaaatca ggccactggt tcaagaaact aagcgacaat aatggatttt aaaaaggact
     8641 ctgactgatt atcccaatcg gtcagagttt tttgcttaca ggagcttaat ttgaactata
     8701 ccaattttta ctcttgacaa gtgaaagaaa caagtatata ctgtttttgc tgattctata
     8761 aaagatgaat tagactatac caattttaag gagaaagcac agcttgcctg tgtcgtatat
     8821 actatgtgtg gaattgttgg tgttgttgga aacacaaatg caactgatat tttgattcaa
     8881 gggcttgaaa agcttgaata ccgtggctat gattctgcgg gaatttttgt cctagatggt
     8941 gctgataacc atttggtgaa ggcggttggt cgtattgcag aattgtctgc caagacagct
     9001 ggtgttgagg gaacaactgg tatcggacat actcgttggg ctactcacgg aaaaccaact
     9061 gaggacaatg ctcacccaca ccgctctgag acagaacgtt ttgtcttggt gcataatggg
     9121 gtgattgaga actatcttga aatcaaggaa gaataccttg caggtcacca cttcaagggg
     9181 cagacagata ctgaaatagc cgttcatttg attggaaaat ttgcggaaga agaagggctc
     9241 tcagttcttg aagccttcaa aaaagccctt cacatcatcc gtggttctta tgcctttgcc
     9301 ttggttgact cacaagatcc tgaagtcatc tacgtagcta aaaataaatc accacttttg
     9361 attggtcttg gagaaggcta taacatggtc tgctcagacg ccatggctat gattcgtgaa
     9421 actaaccaat acatggaaat ccatgaccaa gagttggtaa tcgtcaaggc tgatagtgtg
     9481 gaagttcaag actatgatgg aaatcgtcgt gagcgtgcta gctacactgc tgaacttgac
     9541 ttgtcagata tcggtaaggg aacttaccct tactacatgc tcaaggaaat tgacgagcaa
     9601 ccaactgtta tgcgtaaact cattcaagcc tacacggatg atgctggtca agtagtggtt
     9661 gatcctgcta tcattaaggc tgttcaagac gcagaccgca tctacatcct tgcagctgga
     9721 acatcttacc atgcaggatt tgcttctaag aaaatgttgg aagaattgac agatacacca
     9781 gttgaacttg gcatctcatc tgagtggggc tacggtatgc cacttctcag caagaaacca
     9841 ctcttcatct ttatcagcca atctggtgaa acagcggata gtcgtcaagt tttggtcaag
     9901 gctaatgaaa tgggaattcc aagcttaaca gtgacaaatg ttccaggctc aaccctctca
     9961 cgtgaagcca actataccat gctccttcac gcaggtcctg aaattgccgt ggcatcaact
    10021 aaagcctata cagcgcaaat cgcagccctt gccttccttg caaaagcagt cggagaagca
    10081 aatggtaatg ctaaagcgca agcctttgac ctgattcatg aattgtcaat cgtagctcag
    10141 tctatcgaat caactctttc agagaaagaa accattgaag ccaaggttcg tgaacttctt
    10201 gaaacaactc gtaacgcctt ttacatcgga cgtggtcaag attactacgt agccatggaa
    10261 gcaagtctca aactcaaaga gatttcttat atccagtgtg aaggctttgc tgcaggagaa
    10321 ctcaagcacg gaaccattgc cttgattgaa gaaggaacgc ctgttttggc tctcttgtca
    10381 gatccagttc ttgccaatca tactcgtgga aatatccaag aggtcgcagc ccgtggtgcc
    10441 aaagtcctca ctatcgcaga agagaatgta gccaaagata ccgacgatat cgtccttacg
    10501 accgtacatc catacctctc accaatttca atggtcgtac caacgcaatt agtcgcttac
    10561 tttgcaaccc tccaccgtgg cctcgatgtg gataaaccac gtaaccttgc taaatcagta
    10621 acggtagaat aagctaaaaa agtctagtta tctaggcttt ttctaatgag caaattggtt
    10681 gcttgtactt aagattcgtg ttagaataat ttttcaaatt gaaggacaga gatagacaag
    10741 gagaatcaca atggtagaat tgggaatttc aacatttggg gaaataacgg agcttgaagg
    10801 gactggacaa acttacagtc atgctgaacg cattcgccag ttggtggcag agattgagct
    10861 ggctgacaag gttggtttgg acgtatatgg gattggcgag caccatcggg cggattttgc
    10921 agtatcagcc ccagagattg tcctggccgc tggggcagtc aataccaaga aaatccgttt
    10981 gaccagcgca gtcagcattc tgtcaagcat ggacccgatt cgtttgttcc aacagtatgc
    11041 cactatcgat gctttgtcaa atggacgagc ggagattatg gctggaaggg gctctttcac
    11101 ggaatctttc cctctgtttg gttatgactt gaaagactac gactctcttt ttgatgagaa
    11161 attagacttg cttcagttag tcaatgaaaa gaccaagtta gactggcaag gtcgattgac
    11221 tcaaacgatt gctggtaaag aagtttatcc tcgtccagtt caggacaaat tgcccttgtg
    11281 gatagctaca ggtggtcatg tcgaatcaac agtgaagatt gctcaggctg gtctaccgat
    11341 tgtatatgct attattgatg gtaatccacg ttattttaaa aagttgattc aggcttatcg
    11401 tgagattgga agcgaagcgg gccatgctga caaagacttg aaagtgggag cccattcttg
    11461 ggggtggatt gcggaagatg gtgagcaggc ggtgaaagat tatttccatc cgactaagca
    11521 agtggtggat gctatttcca aagaccgtcc gcactggcag gaattgcgtt atgagcaata
    11581 tttggatcag gtagggtcaa atggcgccat gtttgttggc aatccagatc aggtggccga
    11641 aaaattgatt cgcatgatag aggatttagg attggaccgc ttcatgcttc atctaccgct
    11701 tggttctatg cctcatgacc aggttctgag agctattgaa ctcttcggaa cacaagttgc
    11761 acccaaagta cgagcttatt ttgctatgaa agaggcttaa taaaaaatcc taatcaagtt
    11821 tattaggaca acaaatattg tacgaaaatt aatcccccga gctataatgc ttgggggatt
    11881 tttctatagg agggctagtt tagttctctt ttttattttt tagtaagaaa ccgagaccaa
    11941 ggagcgcaag gaggctgatt cctgcaaata ggagtttgtt ttcgtttttg attcctgtat
    12001 ttggaagttc agcttgtcta tctggggttg caggtatatt tttcttgcta gagttttcta
    12061 ccgattcgtt ttgaaccgct tcttttacag atgatgcttg tgcttcttgt gctggttgtt
    12121 cagcttgtga atcagctgta gcttggctag gtttattttc cgcatcagct actttggcat
    12181 ctggtttagt agaatcaggt ctagcttctg gagctgggtc ttgatatgca gggtgagaag
    12241 cttcattttg atgttcaggc ttggaaggga ttgagtctgg tttctcttct gcagttgact
    12301 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    12361 agcctttttc agtccattca agtcctttcg ggttggcaat ttcgactgat cctgcttggt
    12421 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    12481 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    12541 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    12601 ggtggacacg gtctttgata tcttgaagac tcttaagtcg gaaggcatct gtagattgac
    12661 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    12721 catctgtagc cttagtccag tcaaacttgt tgactgcatc gctagaatcg taagaatcat
    12781 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    12841 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    12901 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    12961 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    13021 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgct atgtattgga
    13081 tgacatctcc agggctgtca gcttcaaagt tagttggttg agcaatgaga tttttaaaga
    13141 tggtgttgac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    13201 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    13261 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    13321 cttcaccaag catgatgagg tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    13381 tagaagcggc gtcatggtct cccatcatat cgaagcggaa gccatccact ttgtaggtat
    13441 caactaggta tttgatagag tcaactagga gccgtttggt catatggtgg gttgtcccca
    13501 agcgtccacc accaaagcta gttcgaggtg tgccatctgc atccataaag tggtagtagt
    13561 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    13621 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    13681 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    13741 catatcccca gttgtagttg ctgttgcttg aagcgtagtc agacaagcgt tcatggtttt
    13801 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    13861 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    13921 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    13981 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    14041 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    14101 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    14161 gacgctcgat ttggtattga taatagtatc cagtgaaatc tgtgattccg agtttgtttg
    14221 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcaagagcg acagttccaa
    14281 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    14341 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    14401 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    14461 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    14521 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    14581 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    14641 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    14701 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    14761 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    14821 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    14881 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    14941 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    15001 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    15061 aagcctcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    15121 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    15181 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    15241 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    15301 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    15361 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    15421 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    15481 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    15541 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    15601 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    15661 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    15721 tctatatcag tatagcatgt agtaaaataa tatgcaagcg ttttctttga tttgtgaaaa
    15781 aaattcttac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    15841 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    15901 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    15961 gaaaattttg ttacaatgat agacggtact ttttactttt ggtctctcaa gagtgtacag
    16021 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    16081 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    16141 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    16201 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    16261 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    16321 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    16381 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    16441 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    16501 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    16561 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    16621 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    16681 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    16741 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    16801 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    16861 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    16921 ggatgctgct aacaacactg gtgcagctgt taagaaacgt gaagatactc accgtatggc
    16981 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    17041 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    17101 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    17161 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    17221 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcccgggt tcaaattagc
    17281 taaatcgatt agtattagct ataactcagc ttaccatcta gtaagttgaa accaacaata
    17341 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    17401 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    17461 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    17521 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    17581 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    17641 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    17701 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    17761 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    17821 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    17881 ctgtaagcac acttcacgat cgtcttcaag caaatgcaca cccaatccaa ttgccaatcg
    17941 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    18001 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    18061 ctcaagaata ccgtgaaaaa ttgattgaag cagttgctga aactgacgaa gaattgatga
    18121 tgaaatacct cgaaggtgaa gaaatcacta acgaagaatt gaaagctggt atccgtaaag
    18181 cgactatcaa cgttgaattc tttccagtat tgtgtggttc agccttcaaa aacaaaggtg
    18241 ttcaattgat gcttgatgcg gttatcgact accttccaag cccacttgac atcccagcaa
    18301 tcaaaggtat taacccagat acagacgctg aagaaactcg tccagcatct gacgaagagc
    18361 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    18421 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaatact tctaaaggta
    18481 aacgtgaacg tatcggacgt atccttcaaa tgcacgctaa cagccgtcaa gaaatcgaca
    18541 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    18601 cattgacaga tgaaaaatct aaaatcatcc ttgagtcaat caacgttcca gaaccagtta
    18661 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    18721 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    18781 cagttatctc aggtatgggt gaacttcacc ttgacgtcct tgttgatcgt atgcgtcgtg
    18841 agttcaaagt tgaagcgaac gtaggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    18901 cttctaccca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    18961 atgtgtggat tgaatttact ccaaacgaag aaggtaaagg attcgaattc gaaaacgcaa
    19021 tcgtcggtgg tgtggttcct cgtgaattta tcccagcggt tgaaaaaggt ttggtagaat
    19081 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aagctttatg
    19141 atggttcata tcacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttt
    19201 cccttaaaga agctgctaaa tcagcacaac cagctatcct tgaaccaatg atgcttgtaa
    19261 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    19321 gacgtgtaga tggtatggaa gcacacggta acagccaaat cgttcgtgct tacgttccac
    19381 ttgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    19441 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaattatta
    19501 agaaaaataa aggtgaagac taatccgtcc tcactctaga aggaagtcac ttagtggctt
    19561 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    19621 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatgcc tgctgaaatg
    19681 agacaggctc ctgctttagc acaggccaat attgagcgag ttgtggttca taaaattagt
    19741 aaggtatggg agtttcattt tgtattttct aatattttac cgattgaaat ctttttagaa
    19801 ttaaagaaag gtttgagcga agaattttct aagacaggca ataaagctgt ttttgaaatt
    19861 aaggctcggt ctcaagaatt ttcaaatcag ctcttgcagt cctactatag ggaggctttc
    19921 tctgaaggtc catgtgctag tcaaggtttt aagttccttt atcaaaattt gcaagttcgt
    19981 gctgagggta atcagctatt tattgaagga tctgaagcga ttgataagga acattttaag
    20041 aagaatcatc ttcctaattt agctaaacaa cttgaaaagt ttggttttcc aacttttaac
    20101 tgtcaagtcg agaagaatga tgtcctgacc caagagcagg aagaggcctt tcatgctgaa
    20161 aatgagcaga ttgttcaagc tgccaatgag gaagcgctcc gtgctatgga acaactggag
    20221 cagatggcac ctcctccagc ggaagagaaa ccagtctttg attttcaagc gaaaaaagct
    20281 gcagctaaac ccaagctgga taaggcggag attactccta tgatcgaagt gacgacagag
    20341 gaaaatcgtc tggtatttga aggggttgtt tttgatgtgg agcaaaaagt gactagaaca
    20401 ggtcgtgttt taatcaactt taaaatgacg gactatactt caagtttttc tatgcaaaag
    20461 tgggttaaaa acgaggaaga ggcccagaag tttgacctca tcaagaagaa ttcttggctc
    20521 cgagttcgag ggaatgtgga gatgaataac ttcacacgcg atttgactat gaacgtacag
    20581 gatctgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    20641 gttgagtttc atgctcatac taacatgtcg actatggatg ctttgccaga ggtcgaagag
    20701 attgttgcaa cagctgctaa gtggggacac aaggcggttg ctatcacaga ccatgggaat
    20761 gtccagtcct ttccacatgg ctataaggcg gctaagaaag cgggaatcca gctgatctat
    20821 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagatg
    20881 gacttatcag aagcaaccta cgtggtcttt gacgtggaaa cgacgggact ttcagctatc
    20941 tataatgact tgattcaggt tgcggcctct aagatgtaca aggggaatgt tattgctgaa
    21001 tttgatgaat ttatcaatcc tgggcatccc ttgtcagctt ttactacaga gttaactgga
    21061 attacagatg atcatgtcaa aaatgccaaa ccactagaac aagttttgca agaattccaa
    21121 gaattttgca aggatacggt cctagttgcc cacaatgcta cctttgacgt tggctttatg
    21181 aatgctaatt atgagcgtca tgatcttcca aagattagtc agccagttat tgatacgctg
    21241 gagtttgcta gaaacctcta tcctgagtat aaacgccatg gtttggggcc tttgaccaag
    21301 cgttttggtg tggccttgga acatcaccac atggccaact acgatgcgga agcgactggt
    21361 cgtctgcttt tcatctttat caaagaggta gcagaaaaac atggtgtgac cgatttagct
    21421 agactcaaca ttgatctaat cagtccagat tcttacaaaa aagctcggat caagcatgcg
    21481 accatctatg tcaagaatca ggtaggtcta aaaaatatct ttaagctggt ttccttgtct
    21541 aataccaagt attttgaagg agtgccacgg attccgagaa cggttctaga tgcccatcga
    21601 gagggcttga ttttaggttc agcctgttca gagggtgaag tttttgacgt ggtcgtttct
    21661 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    21721 ccggctatct atgcgccctt gattgccaaa gagcaggtca aggatatgga ggaactccag
    21781 accattatca agagtttgat agaggttgga gatcgccttg gcaagcctgt tctggctacg
    21841 ggaaatgttc actatatcga accggaagaa gagatttatc gtgaaattat cgtccgtagt
    21901 ttgggacagg gtgcgatgat taaccgaact atcggtcatg gtgaacatgc ccaaccagcg
    21961 ccacttccaa aggctcattt tcgaacgact aatgagatgt tggatgaatt tgcctttttg
    22021 ggagaggaac tggctcgtaa actggttatt gaaaacacca atgccttggc agaaatattt
    22081 gaacccgttg aagtcgttaa gggtgacttg tatacgcctt tcatcgacaa ggctgaagaa
    22141 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gctgccagat
    22201 attgttgatt tgcggattga aaaagaatta acatccatac tggggaatgg atttgctgtg
    22261 atttatctgg catcgcagat gctggtgcaa cgttctaatg aacggggtta tttggttggt
    22321 tctcgtgggt ctgtcggatc tagtttcgtt gcgaccatga ttgggattac ggaggtcaat
    22381 cctctctctc ctcactatgt ctgtggtcag tgtcagtaca gtgagtttat cacagatggt
    22441 tcgtacggtt caggatttga tatgccccat aaggactgtc caaactgtgg tcacaaactc
    22501 agtaaaaacg gacaggatat tccgtttgag accttccttg gttttgatgg ggataaggtt
    22561 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    22621 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    22681 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    22741 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    22801 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    22861 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    22921 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    22981 caggatttgt ctggtattga ccctaataaa attcctatgg atgacgaagg cgtgatggca
    23041 ctcttttctg ggactgatgt actaggggta acacctgaac aaattggaac gcctacgggt
    23101 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    23161 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    23221 ttggggaatg ctcaggatct gattaagcaa ggaatagcag acctatcgac tgttatcggt
    23281 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggctttt
    23341 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    23401 ggctatatcg aagccatgaa ggctaataag gtgccagagt ggtatatcga atcctgtggg
    23461 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    23521 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    23581 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    23641 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    23701 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg taaattagat
    23761 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    23821 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    23881 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    23941 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    24001 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    24061 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    24121 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    24181 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    24241 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    24301 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    24361 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    24421 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    24481 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    24541 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    24601 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    24661 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    24721 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    24781 gtgctattgc tttagcagga atcttttctg ctttgaaaga aaaataaaaa tagaaaagag
    24841 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    24901 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctctctatt gatgtggagc
    24961 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    25021 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    25081 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatcttttg gagaacaagg
    25141 ctagccgtct tggggttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    25201 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gccaatgcga atcgcaactc
    25261 aatctaacaa ggttagctgg actgtagcag ccgctgctgg acttgagtgg gctaagaaag
    25321 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggat caaatcttca
    25381 aaacttgtcg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    25441 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    25501 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    25561 tcaatgcaca gggcgaagaa ttcttgccaa atatgccgac agaagaggtc ttcacagcgc
    25621 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    25681 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    25741 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    25801 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt atcttcttta
    25861 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    25921 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    25981 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    26041 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    26101 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    26161 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    26221 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    26281 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    26341 ctgatactca atgaaaatca aagagcaaac taggaaacta gccgcaggtt gctcaaagca
    26401 ctgctttgag gttgcagata gaactgacga agtcagtaac atatatacgg caaggcgacg
    26461 ttgacgcggt ttgaagagat ttttgaagag tatgaaacga aaaggaggtt ggtcattgta
    26521 ccagcctcct tttgatatga tataatagtt ctatgagatt agataaattt ttagttgcct
    26581 gtgcggtggg aagtcggact gaggtcaaaa acttgctcaa ggctgggcgc gtgactgtaa
    26641 atggtaaaaa agaaaaatca gctaaattgc agattgatga aaaaatagat gagattcgct
    26701 ttgatgggca agtgttggag tatgaagagt ttgtctacta catgatgaac aagcccaaag
    26761 gagttatctc agcgactgag gatcccaagc acagaaccgt tctggacttg ttggatgact
    26821 tggcgcggag taaggaagtt ttcccagtag gacgcttgga tattgacacg catggtcttt
    26881 tgctcttgac caatgatggt cagctggctc atgttcttct ttcgcccaag cgtcatgtgg
    26941 ataagactta tctggcacaa gtcaagggaa tcatgaccca agaagatgtg gagacatttg
    27001 ctgagggtat tcctctcaaa gactttacct gtcaacccgc tatactggag cttgtatcca
    27061 tagatacaga aaagaatcag agccaaatcc gtgtgaccat tgcagaaggg aagtttcatc
    27121 agatcaagcg tatggtgggc tactgtggca aggaagtggt ggacttgcaa cgattgacta
    27181 tgggaacttt agtattagat gagaacctgg aacgagggga atggcgtcgc ttgaccaagg
    27241 aagaattaga aattctccgc gctaatatta tttaatttag tttaatactc aatgaaaatc
    27301 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggcaagg cgacgttgac
    27361 gtggtttgaa gagattttcg aagagtataa attcgaaaaa ggtgagggag aatgtcctta
    27421 ccttttatgt tttttagttg cttcctttgt gaaaagagtt ataatagact gtagaataaa
    27481 aggaggaatc tatgaacgcg attcaagaat catttactga taaactattt gccaactatg
    27541 aagcaaatgt aaaataccaa gcgattgaaa atgctgccag ccacaacgga atttttgcag
    27601 ctctggaacg tcgccaaagc catgtagaca acacacctgt tttctcattg gatttaacca
    27661 aggacaaggt cactaaccag aaagcgtctg gtcgttgctg gatgtttgcg gctctcaaca
    27721 ccttccgcca caaactcatc tcgcaataca aattggagaa ctttgagttg tcacaagccc
    27781 acactttctt ctgggataag tatgagaaat caaactggtt cttggagcaa gtcattgcga
    27841 cttcagacca agaattgact agccgcaagg ttagcttctt actccaaaca cctcaacaag
    27901 atggtggtca atgggatatg gtcgtttccc tctttgaaaa atacggtgtc gtgcctaagt
    27961 cagtttatcc tgagtctgtt tcatctagca gcagtcgtga gctaaatgcg atccttaata
    28021 aattgcttcg tcaagatgct caaatcttgc gtgatttgct tgtttctggt gcagatcaag
    28081 tgactgttca agctaagaaa gaagacctct tgcaagaaat ctttaacttt cttgctatgt
    28141 cattaggact tccaccacgc aagtttgact ttgcttatcg cgataaagat aacaactaca
    28201 aaagtgaaaa aggaatcaca ccacaagagt tctacaagaa atatgtcaat cttcctttag
    28261 aagactacgt ttctgttatc aatgctccaa ctgctgataa accttacgga aaatcttaca
    28321 cagttgagat gttggggaat gtggttggta gccgtgcagt tcgttacatc aacgttccaa
    28381 tggagcgctt gaaagaattg gcgattgccc aaatgcaagc aggtgagact gtttggtttg
    28441 gttctgatgt cggccagctc agtaaccgta aggctggaat ccttgcgaca gatgtttatg
    28501 actttgaatc aagcatggac attaaactta ctcaagacaa ggctggacgt ttggactata
    28561 gcgaaagctt gatgacccac gccatggtct tgacaggtgt tgacttggac gaaaatggta
    28621 aatcaaccaa gtggaaggtt gaaaactcat ggggagacaa ggtcggtaca gatggttact
    28681 ttgttgcctc agacgcttgg atggacgaat acacatacca aatcgttgtt cgtaaggaat
    28741 tgctgacagc agaagaacaa gctgcctatg gagcagaacc aattgtactt gcaccatggg
    28801 atccaatggg agccttggct aaataaaagc atagaaaaaa ggaatcagat tttagaacct
    28861 ggttcctttt tagttgcttg attacatgat gtgaagaaca tgtgccacaa tacccactgc
    28921 gaagagggca aggataatag tgattggaga tacttttttc ttaagtaagt acatgcaaag
    28981 taaagtaagg agtagtcctg ataatccagg aatcaacata tccaagtttt gttggaaagt
    29041 agtaactttt tcaggagttt gagacaatcc ttgtcctact tgtgcgaatg cttcttggat
    29101 acctttagac ccttctggca atttatccca atggatataa gccttttcat ctagttgaac
    29161 tttagaaaca tcgaaagcaa atttaatatt tacccagcgt tgaacaagga cagcaagaat
    29221 gaacatccca aggatagaag ctcctttagt gatatcttga aggataccac cagacatatc
    29281 tttagtgatt tctgatccag ccttgtatcc aatctcttga acataccaca agaatgacat
    29341 acgaatcaag ttccatgcaa caaagaagag gagtggcccc aagatattgc cagtaagggc
    29401 aagtgaagca ccgagagatc caaggattgg gcgtactgta aaccagaata ctgggtcacc
    29461 gataccagca agaggtccca tcataccgat tttaacccct tggatagcag cgtcatcgat
    29521 ttccacaccg ttagcacgtt cttcttcaag cgcaagagta acccccatga ctggagcagc
    29581 tacgtatgga tgagtgttga agaactcaag gtgacgctca agagcagcga tttgatcttc
    29641 ttttttagta tagagttttt tgatagctgg aatgagtgta taagcccagc ccaagttttg
    29701 catccgttca aagttccaag acccttgtaa gaaggttgaa cgccaccaaa cttttttacg
    29761 atctgattta gttaattgaa gtttttcagt catgatgttt tcagtccttt cttatcttag
    29821 tagtcttcta ggatatcgcc gattgggtcg ttagaagttg cggctcctcc gccaccattt
    29881 ccaccagttt tagaaaggtg aaggtagata agagcgatag caacaccgat agcaccgaat
    29941 ccgattagag taatatctga cacagcagcg agaacgaaac caagagcgaa gaatggccat
    30001 acttcacgag ttgccatcat gttgataacc atggcgtaac caacggcaac gaccatacca
    30061 ccaccgatag ccataccatc tttgagccag tctggcatgg cactaaggat actttgtaca
    30121 gtttcagttg gtaccataag gagaagagct gcaggaagcg cgatacgaag tccttggaaa
    30181 agtagcgcaa tgaaatgcgc acgctccaca gcgccgaagt cacctttttt agcggcagca
    30241 tctgcagtat gaaccaaacc aactgaaatt gtacgaacaa tcattgtcaa gaaaagtcca
    30301 gctacggcaa gagggatagc aaccgcttgg gcaacaccga taccagtctt ggtaaagtca
    30361 ccaccaagaa ccatgataat ggcagcagcg acagaagcaa gtgcagcatc aggagcgata
    30421 gcagcaccga tatttgacca accaagggca atcatttgaa gcgatccacc gaggataatc
    30481 cctgcttcca agtgacctgt tacaagccca ataagggtac aggctacaag tggttggtga
    30541 aattggaact ggtcgaggat gccttcaaga cctgcaaaga aggctacaac gattactaaa
    30601 accatagaaa taatagacat gtttaaaatc ctttcataaa taatggctta tttgacattg
    30661 gctttgttaa tcaagtcaaa caaatctttt ttagaatcat ttggtacttt acggacatca
    30721 aattcaacac ccaagtcacg cattttttca aatgtagcaa catcttcttt gtccatagac
    30781 aaaacggtat tgaccaatgt tttacctgtt gagtgagcca tagaaccaac gttaagagtc
    30841 ttgattggca cgccgccttc gatggcacga agggcatctt gaggtgtttc aaacaagata
    30901 agggcatgtg tttctccaaa acgtgggtct tttgaaatct caatcagttt ttgaattgga
    30961 accacgttag ccttgacatt acctggagct gcttgtttaa tcaattcttt acgaaggtcg
    31021 tctttagcca cgttatctga agcaacgatg atacgatttg cttttgaatc tggagtccaa
    31081 gcagttgcaa cctgaccgtg aagtagacgt gtgtcaagac gggcaagatt gattttcaat
    31141 ttaccgtctc cgataacagt tccttctggg atagcagttt gggcaactgg agcagctgca
    31201 gcgcttgcaa cttcttcaac tggatttagc tcttctggaa gagctttgat gccatctttg
    31261 gcttctttaa tgatattagc agcgactttt tctacacctg cagcagcgtc catgaggcgc
    31321 tctgtgtagg cttgaatcaa catcggtaag ttaagtcctg tgatgatggc aaacttacgc
    31381 tcaggatttt ctcccatcac gcgactagct tggttaaatg gagaaccact ccaaaggtca
    31441 gccaaaacta gaacctcatc ttctgcgtca aatgcagcaa cagcgttatt aaacttagcg
    31501 tatagatcat caggaccttc atttggcata aaggtcacaa cttgaacctt ttcttgttca
    31561 ccaaagatca tagatcctga ctgatgaata ccagcagcaa attcgccgtg gctcgcaata
    31621 atgattccga tactcattat tgtcattcct ccttttttgt tttagttttc atttaagaaa
    31681 actttaagac tgtttaagta taaaccgt
//
LOCUS       DAVLMQ010000020        29129 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000020 DAVLMQ010000000
VERSION     DAVLMQ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 29129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29129
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.020"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(164..727)
                     /locus_tag="VXF95_001109"
     CDS             complement(164..727)
                     /locus_tag="VXF95_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1081671.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILSLAIVPRLQTLKK"
     gene            complement(711..1262)
                     /gene="coaC"
                     /locus_tag="VXF95_001110"
     CDS             complement(711..1262)
                     /gene="coaC"
                     /locus_tag="VXF95_001110"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HEV1081672.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLSLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETIDEKTL"
     gene            complement(1274..1963)
                     /gene="coaB"
                     /locus_tag="VXF95_001111"
     CDS             complement(1274..1963)
                     /gene="coaB"
                     /locus_tag="VXF95_001111"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HEV1081673.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPESHPNLSIREITNTKDLLIEMQERVQDYQILIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2193..3863
                     /locus_tag="VXF95_001112"
     CDS             2193..3863
                     /locus_tag="VXF95_001112"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HEV1081674.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKLR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKSQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            complement(4354..5520)
                     /locus_tag="VXF95_001113"
     CDS             complement(4354..5520)
                     /locus_tag="VXF95_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1081675.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLKTEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFLASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            complement(5533..6272)
                     /locus_tag="VXF95_001114"
                     /pseudo
     CDS             complement(5533..6272)
                     /locus_tag="VXF95_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546805.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
     gene            complement(6294..7118)
                     /locus_tag="VXF95_001115"
     CDS             complement(6294..7118)
                     /locus_tag="VXF95_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HEV1081676.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFYSKESFIGYSWKIIPAIKRNPDISHMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIDETYRTKADCQHTAMIGSSLGGNITQFIGL
                     EYQDQIGCLGVFSSANWLHQEAFNRYIECQKLSPDQRIFIYVGTEEADDTDKTLMDGN
                     IKQAYIDSSLCYYHDLIAGGVHLDNLVLKVQSGAIHSEIPWSENLPDCLRFFAEKW"
     gene            complement(7255..8469)
                     /gene="thiI"
                     /locus_tag="VXF95_001116"
     CDS             complement(7255..8469)
                     /gene="thiI"
                     /locus_tag="VXF95_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HEV1081677.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYAQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSSVQEIMRDIYKE
                     GMTFKISSKRSDHNFELDSRELNQTLGGAVFEAIPNVQVQMKSPDINLQVEIREEAAY
                     LSYETIRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            complement(8478..9620)
                     /locus_tag="VXF95_001117"
     CDS             complement(8478..9620)
                     /locus_tag="VXF95_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1081678.1"
                     /translation="MIYFDNSATTKPYPEALETYVQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWVIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKSQGFEVDFSPVYKKGLVDVEALAGLIRPDTILVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDCATFSSHKFHGVRGVGFVYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIHQALL
                     NYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAKSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            9758..10192
                     /locus_tag="VXF95_001118"
     CDS             9758..10192
                     /locus_tag="VXF95_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081679.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTVATIASILGLITASITIMN
                     ALDNNKNTKKEPTTSQTTTIVKEIQKESPQENTSPNKENKTSQEKTQQEETPKSSVKE
                     EKKEEQKTSTQDSSTPAPTPSKPATENEKQSNTPTSENKTNQ"
     gene            complement(10237..12462)
                     /locus_tag="VXF95_001119"
     CDS             complement(10237..12462)
                     /locus_tag="VXF95_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HEV1081680.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDQDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEMAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(12626..14578)
                     /locus_tag="VXF95_001120"
     CDS             complement(12626..14578)
                     /locus_tag="VXF95_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081681.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGAFYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            complement(14575..15486)
                     /gene="pfkB"
                     /locus_tag="VXF95_001121"
     CDS             complement(14575..15486)
                     /gene="pfkB"
                     /locus_tag="VXF95_001121"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HEV1081682.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVESVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDVVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            complement(15483..16223)
                     /locus_tag="VXF95_001122"
     CDS             complement(15483..16223)
                     /locus_tag="VXF95_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1081683.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            16385..16472
                     /locus_tag="VXF95_001123"
     tRNA            16385..16472
                     /locus_tag="VXF95_001123"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:16419..16421,aa:Ser,seq:gga)
     gene            complement(16655..17002)
                     /gene="ssrA"
                     /locus_tag="VXF95_001124"
     tmRNA           complement(16655..17002)
                     /gene="ssrA"
                     /locus_tag="VXF95_001124"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(17536..18645)
                     /locus_tag="VXF95_001125"
     CDS             complement(17536..18645)
                     /locus_tag="VXF95_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HEV1081684.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            18748..19989
                     /locus_tag="VXF95_001126"
     CDS             18748..19989
                     /locus_tag="VXF95_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HEV1081685.1"
                     /translation="MKKIFLTLLTVSLLGGASTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIEQI
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            complement(20220..21632)
                     /gene="sufB"
                     /locus_tag="VXF95_001127"
     CDS             complement(20220..21632)
                     /gene="sufB"
                     /locus_tag="VXF95_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HEV1081686.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFKQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(21686..22126)
                     /locus_tag="VXF95_001128"
     CDS             complement(21686..22126)
                     /locus_tag="VXF95_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HEV1081687.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQTSLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQGQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            complement(22113..23339)
                     /locus_tag="VXF95_001129"
     CDS             complement(22113..23339)
                     /locus_tag="VXF95_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1081688.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILAEGDRVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQFASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVPATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            complement(23350..24612)
                     /gene="sufD"
                     /locus_tag="VXF95_001130"
     CDS             complement(23350..24612)
                     /gene="sufD"
                     /locus_tag="VXF95_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HEV1081689.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKVTANITVEVIARSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSHADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            complement(24640..25410)
                     /gene="sufC"
                     /locus_tag="VXF95_001131"
     CDS             complement(24640..25410)
                     /gene="sufC"
                     /locus_tag="VXF95_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HEV1081690.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            complement(25560..25754)
                     /locus_tag="VXF95_001132"
     CDS             complement(25560..25754)
                     /locus_tag="VXF95_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HEV1081691.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            complement(25782..27437)
                     /gene="dnaX"
                     /locus_tag="VXF95_001133"
     CDS             complement(25782..27437)
                     /gene="dnaX"
                     /locus_tag="VXF95_001133"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HEV1081692.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVCLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            complement(27437..27934)
                     /locus_tag="VXF95_001134"
     CDS             complement(27437..27934)
                     /locus_tag="VXF95_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HEV1081693.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTAWDFTM
                     FEEKS"
     gene            28128..29129
                     /locus_tag="VXF95_001135"
                     /pseudo
     CDS             28128..29129
                     /locus_tag="VXF95_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         8691 a         6272 c         5577 g         8589 t
ORIGIN      
        1 tagaatagta cacctctact tctaaaacat tgttagaaat cgatttgact gtcctgatcg
       61 atttgtcctg ttcttatttc gttttactat agtaaagatt tcattaaaaa gaaactgtat
      121 agagcaaaat ctccaccttc aggtttgaaa gcggagattg tttttatttt ttcaaggttt
      181 gtagtcgtgg aacaatggct agggatagaa ttgcagaaat gaccaattca gcaattgaat
      241 ttgttgagat aacggttgcc agaagaagtt ggatatttcc attataaaca tttccaaata
      301 ggaagaagat tcctccaagg acaaagatag tatttgtcaa ggaaccaagg gccccagcta
      361 aaatcagacc agtcttgttt ttcatcagtt tatagactaa gtaaggagtt aaaccaatca
      421 aaatacgtgg gacaatggca atgatagctg agtagatgtt tccgtttggt acgaagggag
      481 agaagaggta gcttgtcggt agaatcgtaa tcgtgttaac cgtcaagcta agtaatccca
      541 tcaaaaatcc aagtgtaacc ccaactcgtg gaccataaat aatgctggca ataatgacag
      601 gaatatgaac aatggtcggt ttgattggaa atggaaaaag gttaaagata agtgagctca
      661 gaaagtgtat cacgagcatg gtagcaaaaa agatagcaat gggtgcaata ttagagcgtt
      721 ttttcatcga tagtttcctt tattctttct aaaataattg tgaggtcagc taaagctcct
      781 cgtccgtggt ctccacaagc tagtagggat tccttaggag caatcagctg atagccgtag
      841 gtttctaatg ttttcagatt attctgagtt actggatggt catacatttt tgtattcata
      901 gcaggagcta ttagtttggg aatatgactt ggtagggcta gagctgtact ggttaccatg
      961 ttgtccgcaa agccgtgagc tagttttgca atagtgttag cagttgcagg taccacgata
     1021 aataaatctg ctttttttcc aagttcgata tgattgacct gatcaggata gggttccttc
     1081 atgacatcca agtggacagg attctgtgag agtacctgta gtgacaaagg ttggataaac
     1141 tctgtagcag cctgagtcat taagacagtg acttgatggc cttgtttttt tagagaactg
     1201 actaaatctg ccgacttata agaggcgatt gaacccgtta cagccaagag aatgtttgcc
     1261 atagttttcc tttctaagaa tgataggctt gaattttttc aaggaggagt tctgcaattt
     1321 cttctttagt ctggactgtt tgaagctgat ttttctcaac aaatatagct cggtgctgat
     1381 ctgctgaaat ttgagtcagg tcattcgcga tgattaaatc tgcttgattc ttgataagac
     1441 tttttcgtgc aatatcaacc agatgatctt cggtaacatc aaccagcagt ttgaaaccaa
     1501 tcagatgaat agtaggattc cattccttga ctagggatat gattttgggt gtctttttaa
     1561 ggaacaaaac ctgaacctca tcagttgaag aaatcttggc ctgatgattc tgcttgctta
     1621 aaaattcttt tagattggag ctagcctgaa cttcctcaag ccctgtcata taaacaggag
     1681 tgtagtcaga aacagccatt gagtggatca agatctgata atcctgaaca cgttcttgca
     1741 tttctattag aaggtccttg gtattggtaa tttctcgaat acttaggtta ggatgagact
     1801 ctggcttcag agctcgtttt gtcgtaatta aacaaacttc atgccctgca gaaagcaaag
     1861 tttctgtgat aattttcccc aagtgacctg tagaatggtt agtgatagag cggacgctat
     1921 cgatagcttc actggtaccg cccgatgtaa ctaaaatttt catagcacta ttgtacacaa
     1981 aaataagcgg taagtaaaat gaaagtgata aatttttggt aaaaacgaag atttattata
     2041 gtttcaaact ataaagccat ataaaattta agaaaggact ctaaaagtct taaaaacaga
     2101 gatatttacg aacgtttaga gagttttagg atgttaaaaa tcttgttttg tgatataatg
     2161 aattatcata taagaggtta gaggaatttt gaatgaaaac agatattgaa atcgcacaga
     2221 gtattgagtt gaagccaatt gttgatgttg tagagaaact tggtatttct tacgacgatt
     2281 tggagttgta cggaaagtac aaggctaaac tcagctttga taaaattcgg gcagttgaga
     2341 gcaatccagt cggtaaattg atcttggtta ctgccatcaa cccaacacct gcaggtgaag
     2401 gaaagtcgac gcttaccatt ggtcttgcgg atgccttgaa caagattggc aagaaaacca
     2461 tgattgctat ccgcgaaccg tctcttggtc cagtcatggg gatcaagggt ggtgctgctg
     2521 gtggtgggta tgcacaagtt ctgccaatgg aagacatcaa cctccacttt actggagata
     2581 tgcatgctat tacaactgcc aacaatgccc tttctgcctt gattgacaac cacttgcacc
     2641 aagggaatga gctgggaatt gatcaacgtc gtatcctctg gaaacgcgtt gtggacttga
     2701 acgaccgtgc gctccgccat gtgactgttg gtcttggtgg tcctctaaac ggtattccac
     2761 gtgaggacgg ttttgatatt acagttgctt cagaaatcat ggcaattctt tgcttggcaa
     2821 cggacatcga ggacttgaaa cttcgtttgg cgaatatcgt tattggttat cgctatgacc
     2881 gtacgcctgt ttctgtaggt gatttgcagg ttgagggtgc cttggctttg attttgaagg
     2941 atgctattaa gccaaacttg gttcagacaa tttacggtac acctgccttt gtacacggtg
     3001 gtccatttgc caatatcgct catggctgta actctgtttt ggcgacgaca acagcccttc
     3061 acttggctga ttacactgtt actgaagctg gttttggtgc ggaccttggt gctgagaaat
     3121 tccttgatat caagacacca aacttgccaa catctccaga tgcagttgtt attgtcgcaa
     3181 cccttcgtgc ccttaagatg aatggtggtg tggctaaaga cgctctgact gaagaaaatg
     3241 tagaggcagt tcgtgcaggt tttgctaact tgaaacgcca cgttgaaaat atccgtaagt
     3301 tcggtattcc agcagttgta gctattaacg aatttgtatc tgatacagaa gctgaaattg
     3361 cagtcttaaa agaactctgt gcctcaatcg atgtaccagt tgaattggct agtgtctggg
     3421 ctgatggagc agaaggtgga gtagcacttg ccgaaacagt tgttaagaca attgctgaaa
     3481 atccagctaa ctataaacgt ttgtatgata atgacctttc tgtccaagaa aagattgaaa
     3541 aaattgtcac tgaaatctat cgtggtagca aagtgaactt tgagaagaaa tctcaaacac
     3601 aaattgctca aatcgttcaa aacggttggg acaaattgcc aatctgtatg gctaaaactc
     3661 aatacagttt ctcagacaat ccaaatgcgc ttggagcacc agaaaacttt gaaattacca
     3721 ttcgtgaatt ggtaccaaaa ttaggtgcag gcttcatcgt tgccttaact ggtgatgtta
     3781 tgaccatgcc aggtcttcca aaacgtccag cagctctcaa catggatgtt gaaagcgatg
     3841 gaactgtact aggcttgttc tagtggattg aaattgactt taagtgagtt tggaaataat
     3901 atccaagctc attttttctc agactgcaag cagttcatca ataagattta tactcttcga
     3961 aaatctcttc aaactacgtc agcttcacct tgccgtaggt atatgatact gactctgtca
     4021 gttctatcca caacctcaaa acagtgtttt gagcaacctg cggctagctt cctagtttgc
     4081 tctttgattt tcattgagta ttaatagact ggtttggtat cctgaaaact atatcgtata
     4141 ggtgtcgtca tggatccttt tagctgattt aaggatacga aaacacaata ctatgactaa
     4201 attgaaatgt taaaattcaa tttctagcca cctaatcctg cttcaaatag ttatcgaaca
     4261 agttttatga tagctacctt gttaggatgc tcttattttt taccagacaa aacaaaagga
     4321 ttaagggagt gaatttcctt aatccgatag ttcttattct tgacgttgtc cgaaatcagc
     4381 aatcatctga tccatttctt gtcgactcgg agttgtcagc atatacaggt aatctccttg
     4441 aagttccgcg aaggcagctg gcatgacttt tttaaccttg aactgctggc tatatttggc
     4501 aagcaaatcc tcttctgaat aaacatagtg agcatttgca cggcgagaag tagccaaaca
     4561 atactgagtt tcaaagtctg acgccaggaa ctcctctcct gcgacaatag ctgcatagcc
     4621 acgataaagg tccaaggaat gagcaaagtt ataaacatca atggtaaaac cacctgcagg
     4681 gcggttattg tactcgatgg taatataatc gtccccctca cggaagaact caatatggaa
     4741 aaaccgttct ttcataccaa attctttgac aattgcttcc ccatacttgc gcagtttagg
     4801 atccatatcc ttgagcacat aataagaatt gtccatctta taaatcatga ggtcaagcgg
     4861 tgtataggcg tagtcaaagg ttgttgagaa gacaatcttt ccatccttgt ccacgagccc
     4921 gtcaaaggta cagatttcgc tggaagtgac aaatttttca aagaaataaa gggttgaatg
     4981 gtcccattct tgcttgaagt gattgatatc gtcttctgtc ttaagtttaa aggttgcggc
     5041 tgctcccact ccattatcag gtttggcaat cattggaaga ccgatttctt tcactgcttg
     5101 atcaacatct gcttccgtct tgataacagc tccaggtacc acaggaacac ctgctttttt
     5161 gaaaagtttc ttcatttcag acttatattt cgtctttttg agatcctctg gtttggcacc
     5221 aaaaacattg aattgttctc tgagtgttgc gtctagctca agccagtatt cattgtgaga
     5281 ctcgatgcgg tcaattggac catgtttata aaagagaaaa gcaactgcac gtttgacttc
     5341 atctatgttc tcaagattat caacacgaaa atactcggtc aagctattgc gcaagggctc
     5401 atccaattgc tcgtaagact cttgaccaat tcccaagact gtgatgcctt tattagctag
     5461 ttcgatggta aactgttgaa agttttgtgg atagtaggga gaaataacaa ggtaattcat
     5521 aggtaactcc ttttataaat agagattacc gaggaaataa ggcatttgtt tacgccacca
     5581 ttcccagtca tgggcgacat catgtcccca ttcagcaaac caggctggaa tttgtttctt
     5641 gtcaaaggct tctttgagct tgtaaaagga tggcaaacca tcttgttccc aggctccaag
     5701 ccccgtacac agcacaatct ctgcctgacg gtaacggtca ataaaccagc cgtcgttttg
     5761 gttccaaata taatctactg gcgagttttg gtaaatagca tcatcgttgt agtaatcacc
     5821 gacaaagaaa cgtgcgtcgt aaacaccact gagagcaatc actttggtaa agacatctgg
     5881 atgctggagg aagaaattga gtgcatgata ggctcccata gagcaacctg tcgtcatcat
     5941 gccatcaaac caacctgtct tgtgcttgat aaaagaatgg cctcctcaat cacataacat
     6001 tcgtaggcac ggtgcatttc cgcttggtca tgagcatttt tccaagtagc caaccagctc
     6061 tcactatcca cactagatag ggtaaagaac tagacaaggc cttcctcgat aaaggaagca
     6121 caggcatcaa tcatgccaaa atcatagtat tcgttgtgac taccacctga tgaagcaaag
     6181 accacaactg gaatcccacc atgtccataa cggttaaggt acatttcacg gttaggatga
     6241 ccactccagt ggctaagatg ttcaatatgc atttcgtttt ttcctttctt aacttaccat
     6301 ttttctgcaa aaaatctcag acaatctggt agattttctg accaagggat ttcactatgg
     6361 atggcaccag actgaacttt tagcacaaga ttatccagat gtactccccc tgctatcaaa
     6421 tcatggtaat agcaaagcga cgagtcgata taggcttgtt tgatattgcc atccatcaag
     6481 gtcttgtctg tatcatctgc ttcttctgtt cctacataga tgaagatgcg ctggtcaggc
     6541 gatagtttct ggcactcgat atagcggtta aaggcttctt ggtggagcca gtttgcagat
     6601 gaaaaaacgc ccaagcaacc aatttggtct tggtattcca aaccgataaa ctgggtaata
     6661 ttgcctccta gtgaggaacc aatcatagcc gtatgctggc agtctgcttt tgtacgatag
     6721 gtctcatcga taaaaggctt gaccacctcc atgacaaact cagcatactc cacaccctta
     6781 ccaccaaact gctgctctgg gataggagat tcttggaact tccaagccgc atactcattc
     6841 attcgcccca taccatcatt gtcaatagca acgacaatca tgtgactgat atccggattt
     6901 cgtttgatag ctgggataat cttccatgaa tatccaatga aagactcttt gctataaaaa
     6961 acattttgcc cgtcatgaaa gtatacaaca ggataggaac ggtctgtatc tttctcataa
     7021 tctttaggaa gaagaatacg tacacggcgc tccttacctg tataaggaac cttgagtttg
     7081 tgttctttca tttttagata aaagtaggat tgattcattg tcagaaaact ctctatattc
     7141 aaaattttat atcattatat catgaaaata gaaaaaagtt agttttttac ctgtttttag
     7201 aaaaaaaaac taactttttt tactgatttt cgctattctt ttggattttc tgaattagag
     7261 tagattatca atcaagtcat caacttcatc tttttcggct tgaggtgtga tttcagtaat
     7321 catgattcca gccactgctc gctcaaccaa gccttcaaca tccatacgcg cttcgtactg
     7381 ctccgcattc ttaattttag gatttgtttt tggacgatct ggtgcaaaaa tggtacaaca
     7441 gtcttcaaac ggttggattg aaatgtcaaa ggtatcgatt tcctgggcga tgtcaatgat
     7501 ttccaacttg tccatggtaa ccacaggacg aatgatggga gtgttggtaa cagcattgat
     7561 agccttcata ctttcaaggg tttggctggc tacttgacct agactttccc cattgatgat
     7621 aaccaaacca tttcgtacct cacgaatacg gtcagtaatc cgcatcataa agcgacgagt
     7681 tagagtcatc aaataagctt ctggcgcttt ggctttgatt tcctcttgaa tctctgtgaa
     7741 aggcacctcg ataaactgga tatttccgcc aaacttggtc aatttacgtg tcaagtcctg
     7801 cgctttcttg agggcaccag gactagtata tggtggacta gcaaagtgaa ctgcctcgat
     7861 atccacccca cgcttaagag caagataacc tgctacaggt gagtcaatcc ctcctgacaa
     7921 catgagcatc cctttacctg aagttccaac tggcaaacca ccagccccac gaatggtttc
     7981 ataagaaaga taggctgctt cttcacgaat ctccacctga agattgatgt caggactttt
     8041 catttgaact tgcacatttg gaatggcttc gaatacagcc cctccaagtg tttggttgag
     8101 ttcacgacta tcaagttcaa agttgtggtc gctacgcttg ctagaaatct taaaggtcat
     8161 accttccttg tagatgtccc gcataatctc ttggacagaa gacttcaaaa cttctacaga
     8221 tttttcaacc ttataaacag gagaaaagtt ttgaattcca aaaacttgtt tgagagattc
     8281 tgcaactgct gtgtaatcag ctccattgag gtaagcgtgg gcacggtcgc gatctgctgt
     8341 taccttaact tgggcataga tagacaaaac gtccgaaata ttattacgaa gtttattgat
     8401 gaaacgcata cggtttttac ccttggttga caactctccg tagcgaatca taatttctga
     8461 atactgcatg aatgctccta tcttactttt ctagtttgat tgtaaatcaa ttttaacttg
     8521 gtcaaaaact gctcgacctg actcatatca ttttccaagt ctaggctaag acgcacagct
     8581 gacttggcct tatctttgtc cactcccatg gcaatcaagg taccggctgg ttttcctgcc
     8641 ttagatgaac aagctgaggt tgttgagatg aaaatatcat agtcttcaaa ggcgtgaacg
     8701 atgacttcac ctcgaacacc tttgattcca aaagtcagaa tatgaggtgc aaagtcttcc
     8761 tcatctgaaa agacaaaaat atccggatag ttcagaagag cttggtgaat cactgccttc
     8821 atctgcccag tcttgctcct aaagatatct agcttttcca tagataaacg gagagccttg
     8881 gctgtcgctg caatccctgc cacattttca gttgtcgaac gataatctcg ctcctggcca
     8941 ccacctgtaa gaagaggtgt aatcttcttg ccagatttga tatagacaaa gccaacacca
     9001 cggacaccat gaaatttatg actcgagaag gtcgcgcaat ccacccgttc tgtcagatac
     9061 ttttcagtcg gaattttggc aagcgcctga accgcatcaa cgtggaagga aatagtcggc
     9121 ttgtctgcca agaattctga aatagcctca ataggttgga tagagccgat ttcattgttc
     9181 acagccatga tggaaacgag gattgtatca ggccgtatca aacctgctaa cgcctcaaca
     9241 tcgaccaagc ctttcttata aactggagaa aaatccactt caaatccttg acttttcaac
     9301 cagagggctg actctttgac tgctggatgt tcaatggctg aaacaatgat gtgcttgcca
     9361 aactgagctt tttcaaaggc cacacccttg ataacccagt tatccccttc tgttccacca
     9421 gaggtaaaga agatttcatc gcttttctta ccgattaaat ctgcaatctg ttggcgagaa
     9481 gcatctaaga ttcgtgttgc ttggtctccc aaacgatgga gactagatgg gtttcctaaa
     9541 atttttgaag cgacctgcac ataggtttca agggcttcag gataaggctt ggtcgtcgct
     9601 gaattatcaa agtaaatcat gtttctcacg ctttctaaaa tcactccctc tattgtatca
     9661 tgaaacggag cttgcgacaa gaaagggcaa tttctctttt tttaagattt ttttaaagaa
     9721 acagagtata ataagtcata atcaaaggag agaatgtatg tctaattatc gtagaacttc
     9781 aaaaccaaaa acagaacaca tcaaaaaagg ctttacagtc tttcaaaaaa ccgttgcgac
     9841 tatcgctagt atccttggct tgattaccgc tagtatcacg attatgaacg ccttggataa
     9901 taacaaaaat actaaaaagg aacctacaac aagccagacg acaacaattg tcaaagaaat
     9961 tcaaaaggaa tcccctcagg aaaatactag tcccaataag gaaaataaga cttctcaaga
    10021 aaaaacacaa caagaagaaa cgccaaaatc cagcgtcaag gaagagaaaa aagaagagca
    10081 gaaaacatca actcaggatt cttctactcc tgctcctact ccaagtaaac ctgctactga
    10141 aaacgaaaaa cagtccaata ccccaacttc ggaaaataaa actaatcaat aatcactaaa
    10201 atagcctcct tccaaacttg gaaagaagct atttttttat tgttgtaaaa cttttcttgg
    10261 tttggtacct tcagctggac caatgacacc tgccatctca agctcttcca tgagacgggt
    10321 cgcacggtta aatccaactg acaaacgacg ctgaatcatg gatgcactgg ctttctgtgt
    10381 ttcgataacc aaagacttag cttcttcaaa aagcggatca ccaccagcat ctccatccga
    10441 aaattctcct tcattttcag aaacctcacc tggatcaaaa ctctcatcgt agtctgcatc
    10501 tgcctgagtc ttgatgaagt tcacaatgcg ctcaacatcg tcatccgaga taaaggagcc
    10561 ttggagacga actggatgat tttcatcaat cggtttaaag agcatgtctc ctcgaccaag
    10621 aagtttttct gctccatttt catccaaaat cgtacgggag tctgttcctg atgaaaccgc
    10681 aaatgctaca cgagatggaa cattggcctt aatcaaacca gagatgacat caacagatgg
    10741 acgctgagtt gcaagaatca tgtggatacc tgcagcacgc gccttctgcc caagacggat
    10801 gatagcatct tccacttcct tgctggccac catcatgagg tcagccaact catccacaat
    10861 cacgacaatg aatggtagcg gaatttgctt gtactcagac tgggaattga actcttctac
    10921 cttggcatta aaacctgcaa tattccgaac tcccaccttg gcaaagagtt cataacggtt
    10981 ttccatttca tccacaacct tttgcagagc cttgctggct ttacgtggat tggtcacgac
    11041 tggaatcaag aggtggggaa tatcattgta aacagataac tcaaccatct tgggatcgac
    11101 catcataaat ttaacttgat ctggtctcgc cttcatgaga atgctagcaa taatgccgtt
    11161 aactgctact gacttccctg aacccgttga acctgcaact agcaagtggg gcattttaga
    11221 aaggtcaaaa gctcttgcgg ttccattaac agccttccct aaaggaattt ccaagaaatt
    11281 ttctgctttc gtttgcgatt gttcccatag ttctcggaaa gatacagtgg caatatcgga
    11341 gttgggcact tcaattccga ttagggattt cccagggatt ggtgcttcaa tccggacatc
    11401 tttggcagcc aaggctagag cgaggtcatc tgatagattg gaaatgcggt tgacccttac
    11461 accaacagcc ggcttgactt catacttggt cactgatggc ccaatttcgg cccgttcaac
    11521 tgttacctta ataccaaagc tagcaaaggt tgcttctaag attttgatat tttctctgac
    11581 aattttcttc tctttagact gatcttttgg tttatctggt gcaaagagtt gtaagcttgg
    11641 aagtttgtat tcaagggctt ctttggctga aaaatcgacc tgaacatctt ggtcatctga
    11701 gtcatcttcc tgttcaggga atttaagttc agcttgaggc aggatgattt ctggttccac
    11761 ccacttttct tctggaatag gtggaagatt ttgaacagct tcctctgtca gaatttcacc
    11821 cgtttccata tcaacaggag gcaaatcgag taaggctttt tcagtctctt cttgttctaa
    11881 tctagcctct ttctcagcct tttggcgagc tttttcttct tgtttgacaa agcgttcctc
    11941 ttttcgacgc tcgtgccctt cccaccattt ggcaaagcct ctactgaaaa attcagcaat
    12001 atcgtaaaca gaccaagggc tgactaggag agaacccact aaaatcaaga tagaaccaat
    12061 aaagtaagtt ccgatatttg aaaagagaaa ggctgttgga atataaagag cgaccccgat
    12121 caagccccct ccagcaaagc tagtcgttcg aaaaccagtc agatctgtca caacctgagc
    12181 catggtccct tttagaacgg acttgtccaa accatatttc caaactaagt aggcctcaaa
    12241 aatcaagagt aagccagcaa atatggtgaa aaagccagat aagagtcctt cctgttttcg
    12301 tatccacttg aaaaagaaga gatagattaa taggccgaat atcgccagat aagctaggct
    12361 acccactagc aagcgaatta aattataaag ggttatacct gcagccccta atttgaaggc
    12421 tgcgaaaatc aataaaatcg caattcctaa tgaaatcaac attcgttgaa tcgcttcttt
    12481 tctttccagt tctgctttag acggtctccg tcttgttgta cttgtattct tgtttgccat
    12541 tcttctatta taccatattt cacaggcatt tcgggaagag aaaaagactg caccaaacgg
    12601 tccaatcttt tcatttttct attttttatg cttgtggttt gcgtaggtaa ccataaacca
    12661 caccacttac gattgctcct accaagacag aaacgaggta aaggagagca tttgaagtaa
    12721 gggcgataac gaagattcct ccgtgtggcg ccatgagttt gataccagta agaccaacga
    12781 gtccacctgc tactgctgaa ccaaggatga agcttggaat cgcacgagct gggtcagcgg
    12841 caccaaatgg aatcgctccc tcagtgataa atgacaagcc catgatgatg tttgtcaaac
    12901 cagagttacg ttcttcctta gtaaatttat ctttgaaaag aagagttgcg acaaagattg
    12961 caagtggtgg caccattcct ccagccataa ctgctgccat ggctacagaa ccacctgaag
    13021 aaacagttgc tgcaagcgta cctgtaccaa agacataagc tgctttatta actggtccac
    13081 ccatgtcaac agccatcatt ccaccaagga cgataccaag aaggacagct gaacctcctc
    13141 caagaccgcc taggaagtca ttcatagcag tgttgattgc agccattggg atattcacag
    13201 ctagcataac aaatcctgtc aagattgttc caagaagtgg caatagaagg attgatttag
    13261 caccttcgag tgaacgagga actttaacgt atttcttgat ggcaagaacc aaggcacctg
    13321 cgataaatcc accaacaagg gcacctagga aaccagatga gacacctgca agagttgaag
    13381 ttgcttcacc acctgcggca taaggaattt taccaaaggc aaaaccttct ttggcaatag
    13441 caccagccac gaaacctgct accaaacccg gtttttcagc aatagagtag gcaacataac
    13501 ccgcaaagac tggaagcatc aaaccaaagg cagctccacc aattttcatg aacatagaag
    13561 ctaactcatg gtaagaacca agattgccaa ggttttcatt tggaacaccc aaagcaccgt
    13621 caatcaagaa ggcaagggca atcatgatac caccaccgat aacgaatggt aacatttgag
    13681 atacaccact catcaagtgt ttgtagaagg caccaccaag gctttgtttt tcgttagagg
    13741 ctgttgcagc tttggcacca ttagcggcac ggtagacttc agtatctcct gaaagagcca
    13801 agttaattag ctcttctgtc ttacggatac cgtcagcaac tggacgattg atcaatggtt
    13861 ttccatcaaa tcgatccatt tcaacggcct tgtctgctgc aatgataata gctttagcct
    13921 tacggatatc ttctgcagtt agttgatttc caacaccgct agcaccgttg gtttcgacct
    13981 tgataccaac ccccatttca gcagctactt tttgaagggc ttcttgggcc atgtaagtgt
    14041 gggcaatacc tgttgtacaa gctgtaacag ctacgataaa gtcaccagag tcattagcag
    14101 gtgcttgaac aagttcctca gttttttctg aagcttggtc aaaaagttcg ataacttggt
    14161 ctgcagatgt tgcttgacga agtttgtctg caaaaccgtc tttcatcaag tattgagaca
    14221 attctgccaa ggctgccaag tgagtatcat tggcaccttc tggagctgca atcatgaaga
    14281 agaggtcagt tgcttgtcca tccaagctct cgtagtcaac acccttattt gacttagcaa
    14341 atagaactgt cgcttctttg acagcagcgt ttttgctgtg aggcattgcg attccatcac
    14401 ccaaaccagt agaagtcaaa gcttcacgcg ccaaaattcc ttctttaaat gtttcaaaat
    14461 ctgttacata accgtgctct gtcaaatttt taatcatctc gtcgatgaca gctgtttttt
    14521 cagttgcctg caaatctagc aacatgacat cttttctcaa taggtcttga attttcatct
    14581 tttttctacc tcaacttttc catatgtttc tttaataaat tccgccgttg ccaagtcatc
    14641 tgagaaggta gttgccgttc cgcaagccac tccccatttg aaggcttcta ctacgtcttt
    14701 tgatttgaca aattcacctg tgaatccagc aaccatagaa tcaccagctc caactgaatt
    14761 tttgactgtt cctttgattg gtttagcgaa gtaagctccc tcagatgtga caagaagggc
    14821 accatcacca gccatagaga taataacatt ttgagcaccc ttagccagta actcacgagc
    14881 gtatttctca atttcatcta aactttcgag tttaacccca aaaatcgctc caagttcatg
    14941 attgtttggt tttacaagaa gaggctggta gtccaaacta tcaattaagg tctgtccttc
    15001 aaagtcacag accacttgcg caccagtctg gcgcgtcaag gaaatcaaat ccttatagat
    15061 aacattgcct agatttttag cacttgaacc tgcaaagaca actgtatctt ctgctgtcag
    15121 actagataaa atagctttca attcttctag ctgaaccgat tcaacagttg gacccgttcc
    15181 gttgatttct gtttcttggt ctgctttgat tttaacattg atacgagtat cttctgccac
    15241 ctggacaaaa cgtgtctcga tttcttcctc tgctaaagta tctgtgataa atttaccagt
    15301 aaagccaccg ataaatcccg tcgctgtatt tggtatattc aaacgtttca agacacggct
    15361 gacattgatt cctttcccac cagcaaactt atcatcactg tccatacgat ttacactacc
    15421 aactttgact tggtccaaac gaacgatata gtcaatggat ggattgagtg tgactgtata
    15481 aatcatactt ctattacctc cgttttctcc ttaataacct gcaagagctc atgcccttga
    15541 ctagtgataa cgatagcgcg tttgagtggt gctaccttgg caaagcaagt ttgtccaatt
    15601 tttgacgaat ccaccaagac gtaggtctgc ttggcattct ccaaaatagc tcttttcaca
    15661 gctccctcct ccatatcagg agtcgtataa tagccatcgt caacaccatt cattccgata
    15721 aaggcacggt caaagtgcaa ttggttaatc tggttaagag caacgccccc gatactagca
    15781 tctgtcgccg tcttgacgtt tcctccaacc atgacagttg gaatctgctt ttcaaccaac
    15841 tgagcggcat ggtgaatgga gttggtcaca actgtaacat tcttattgac caattcatga
    15901 atcaaaaaag cagttgttgt tccagcatcg ataaagatga catctttttc tttaatgaga
    15961 gaggctgctt tctgagccag caacttcttt tcttgaaggt ttttgacaga tttttcttga
    16021 atggtttctt cttcctgtaa ggagtggggg agttctgctc caccatgcac acgacgaagc
    16081 ttgttttccg cttccaactc atccaagtct cttcgaaccg ttgattctga cgtttctagc
    16141 aaactaacta atttttctag agaaactaca tgatgctgat ttaactcctc taaaattagt
    16201 tgtttacgtt ctgtttttaa cactgaatca cctcctgtta tcgtttacac tattcattct
    16261 atcatacttt ctttcgaagt caagcatttt ttatcatttt ctttcaaaat ctatcatttt
    16321 tcttatttct agaattttta ttgcaagata agagccttta tggtagacta tttgagtaag
    16381 tattggaaga ttactcaaga ggcttaagag gccgtgttgg aaacgcggta ggcgtgtaat
    16441 agcgtgcgtg ggttcgaatc ccatgtcttc cgtcgaaaaa agattatttt taggatgcga
    16501 caaatgttgt atcctttttt ctatcctttt tttaaaatag ggtctgtttg tgactccctt
    16561 tttagcaaaa gaatgcaaag gaataccaaa gataaaaata aaaaacgttg atttaacaac
    16621 gttttaccaa ggaatgcaaa agaatgcaaa ggaataatgg agccggtggg agtcgaaccc
    16681 acgtccaaac acctgccaac atatttgtct acaaccatag gttatgtatt attttaacag
    16741 cccctcgaca cataactcaa gtctagaaac tgcgagtcta tcaatctctt atcaagccgc
    16801 tagacaaggc ttaatcgtat ctcgctaata ataagacctg tcattgaaca cgagcaatcc
    16861 aaatcgggtc acgcctgctg gtttttaggc agctagagcg taagaagtgt tattttttgc
    16921 agttatattt aactgagcgt ttacgtcgcc acacgagtcg caaaatatgc ctcataatgc
    16981 ctgtcgaatc cgtaacgacc ccaaaagaca ataaaaccat tataccttat ctaactcaaa
    17041 aatgcaaaaa gaaatcacat acctaagatg aagctatctg ttttgaagaa attcacgaag
    17101 agaattattc taaaatactt tcagatgaga attttcgtac tctctttatt tcaattcatt
    17161 tgagtttaaa aactataaaa tcaatcctta tattattcgg tctacttttc acttattgca
    17221 ccaaaatata gtaaaatgaa ataagaatag aacgaataga taaggacagt caaatcgatt
    17281 tctaacaatg ttttagaatt agaggtgtac tattctagtt tcaatctact ataaataggt
    17341 ttcattcgaa ctttaataga ctatgaaaac cagtggaact taccctgaca cagaattcca
    17401 ctggtttttt cgatttttat cagattaact tctactattc ttagctgtga aaattagttt
    17461 aagactttaa cttattttca gtcttctaat ctaaaggcca cttccagtaa agaaaaatca
    17521 gggttctcct gacttttact tagctaattc tctttctcgt tctttcatta ttttatgatt
    17581 ttcatacaaa cgggataaga acttagaaat ttctttcaag atagaatagg ttggcactgc
    17641 gacaatcatt ccaactacac catagatatt gcttgacaac aaaagtaaaa ctaaaatcgt
    17701 gattggatga accttcataa cacttcctac gattcgagga tataagatat tgccatctac
    17761 ctgctgaaca acaagcatat aaatcactgc aatcagcagt ctatggggat cagtgaatat
    17821 atttgcgatg atcataggaa tcaaaccaat acttggcccc acataaggaa ttaaattggc
    17881 tacaccagaa aaaatggcaa aaactaaagc atattttaaa ccaataatac tatagccaat
    17941 ataagccaaa caacctataa tgattgcgtc aatcgaaact ccactaatat agcgagcaat
    18001 cgtcgcattt aaattcttta ataagcctgc aatatgcaag cgatccctct ttagaatcgt
    18061 tctttcaagc atgggcaaga atttatgtcc atctaataag aaataaacca aaaaaactgg
    18121 agtcataatc aaaatcaaaa cagtactgat aagagctgac aagacgctcc ccacactatt
    18181 tgatacgcta tttaggatat tttgaagaat atccacatag gataagttta actgctgaat
    18241 tgtagcttct acatccaaat tctggagcgc aggataatta gataagtcta tgattaagtc
    18301 ttgtactcga ctataaatag tttgactaga tataatcaaa ctagataact gattaatcaa
    18361 aataggtaag agatagacaa cacctatgac cattccccag accaaagtac acaaggtaat
    18421 taaaatacca agcaaacgat tgagtttaca gactttattt aagaaagtaa caatagggtt
    18481 tgtcaaataa taaagaaagc ctcctaataa aaatggaatc ataattgtat taagcacgct
    18541 aacaaaaggg ttaatcaaag accccatctg tctccatagg taaaagatga tggttaagag
    18601 taaaatttct gtggtccaaa aaaataattt atttctacga aacatgagtt acctccctca
    18661 ctttatttta ccatattttc aaaaagctta acagatgaat tattaaagca agaatatttt
    18721 ttttctttat gatagaataa gactactatg aaaaaaatat ttttaacttt gttaactgtc
    18781 tctcttttag ggggtgcttc tactgctgtt gctcaagatt ttaccattgc cgctaaacat
    18841 gcgattgctg ttgaggcaaa tactggtaaa attctctatg agaaggatgc aacgcaacct
    18901 gtcgaaattg cttccataac aaaattgatt actgtttatc tggtctatga agctttggaa
    18961 aacggaagta ttaccctctc cactcctgta gatatttctg attatcctta tcaattgacg
    19021 acaaattctg aagccagtaa tattcctatg gaggcccgta attatactgt cgaagagttg
    19081 cttgaagcaa ctctggtatc tagtgccaac agcgccgcta ttgccctagc tgagaaaatt
    19141 gctggctcag aaaaagattt cgtcgatatg atgcgggcaa aactcttgga atggggaatt
    19201 caggatgcca ctgttgtcaa tacgacaggt cttaacaatg aaactctagg ggataacatt
    19261 tacccaggtt ctaaaaaaga tgaggaaaat aagcttagtg cttatgatgt cgctatcgtt
    19321 gctcgcaacc tcatcaaaaa atacccacaa gtcttagaaa tcactaaaaa accttcttct
    19381 acttttgctg ggatgacaat cacttcaacc aactacatgt tagaaggtat gcctgcttac
    19441 cgtggtggtt ttgatgggct aaaaacagga acaacagata aggctggaga gtcttttgtt
    19501 ggtactactg tcgaaaaagg catgagagtc atcacagttg ttttaaatgc agatcatcaa
    19561 gacaataatc cttacgctcg atttacagct acatcttccc taatggatta tatttcttct
    19621 acatttacac ttcgcaaaat cgttcaacaa ggcgatgcct atcaagatag caaagcccct
    19681 gtacaagatg gaaaagaaga tacagtaact gcagtggctc cagaggatat ctatctaatc
    19741 gaacagattg ggaatcaatc ttcccaatct gttcaattca cacctgattc caaagcaatc
    19801 ccagcaccac ttgaagctgg aacagtggtt ggccatttga cttatgaaga caaggacttg
    19861 attggtcaag gttacatcac cacagagcgc cctagtttcg aaatggtagc agacaagaaa
    19921 attgaaaaag ccttcttctt aaaagtttgg tggaatcagt ttgtccgctt tgttaacgag
    19981 aaattataaa aaatcgcgat tttaaaccgc gattttttga tacaagttca tcttcaaaat
    20041 ccttgatttt gagtaaatct aatactcaaa atcaaagaac aaactaggaa gctagccgca
    20101 ggttgctcaa aacactgttt tgaggttgta gatgaaactg acgaagtcag taaccataca
    20161 tacggtaagg cgatgctgac gtggcttgaa gagattttcg aagagtataa aatcaaattt
    20221 tatccaactg atccctccat ttcatagcta atcaagcggt tcagctcaac tgcgtattcc
    20281 attggaagtt cttttgtaaa gggttctaca aatcccatga caatcatttc agttgcctca
    20341 gattctgaca atccacggct catgagataa tacaattgct cttctgaaat cttagatact
    20401 ttggcttcgt gttccaaagc cacttgcgag ttgtgaattt cattaaatgg aatagtatct
    20461 gatgctgaca agtcatccat gataatggta tcacattcaa tgtgggaaac agatttctta
    20521 gagttcttgt taaaggtgac ttgtccacgg tagtcaacct ttcctccacc tttagcgatg
    20581 gatttagaca caatagacga gctggtatgt ggagcattgt gaatcatctt agcacccgtg
    20641 tcttggtgtt gccctgcatt agcaaaggcg atagagagca tggtaccacg cgctccttct
    20701 ccatcaaggt aaacagatgg atatttcata gtcgttttgg cacccaagtt tccatcaatc
    20761 cactcaacag tagcatcctt ttgagcctta gcacgctttg ttaccaagtt atagacgtta
    20821 tcagaccagt tttggatagt tgtataacgc atataagctc cgtccaaagc aaaaatttct
    20881 acaatggcag cgtgtaagct attgcttgaa tatgttggtg ctgtacatcc ttctacgtag
    20941 tggacgcttg ctccctcatc aacgataatc aaggtacgtt cgaactgacc tatattttcg
    21001 ttattgatac ggaaataagt ttgaagtgga atatctacct tgacaccttt tggcacgtag
    21061 ataaaagttc cacccgacca tactgctgag ttgagggctg ccaacttgtt atctgtcggc
    21121 ggtaccaact tcgcaaagta ttgtttaaat aagtctgggt attccttgag tgcggaatct
    21181 gtatctgtaa agataatacc taatttttgg aactcttcct tcatgttgtg gtaaaccact
    21241 tctgactcgt actgggcaga agcccctgct aaataagcac gttcagcttc tggaatcccg
    21301 atacgttcaa aggtttcttt aatcttttca ggtacatcat cccaagaacg ggctggtttg
    21361 tcagatggtt tttggtagta gattaagtca tcaaagtcaa tctctgacaa gtctgctccc
    21421 caagtttgca tgggcatttt tttgaaggtt tcataagact tcaaacggaa ctccaacatc
    21481 cactcaggct cacccttagc agcagataat tcacgaataa caccttcgtt gagtcctttt
    21541 cctgtcgata agacaggctc tacatcgtca tggaaaccaa atttatattc accaaggtca
    21601 attggttttg gttctactct ttcttcagcc atagtatcct ttctttcttc atttctaata
    21661 attcataaga caaaagaaac ttgtcttact gtttttcttg attttcaatt gttttcttaa
    21721 gggcattcca agctagggtt gcacacttga ttctttgagg gaatttggca acacctgaca
    21781 agaatgccgc gtctccaagt tggccttgac gctcatcttt ttgcccttga accatttcag
    21841 aaaaaatagt cgccagttct aaaatttctt gtttggtttt tcctaaaacg gcatctgtca
    21901 tcatactagc agaagcagtt gaaatcgtgc atcctgaatt tagaaaagca atatcttcca
    21961 aacggtcctc tgcatcaaac ttgacagaga ggttgatgac atccccacaa gtcggattgt
    22021 tgagactggt ttgctcagca tcttctaact tcccttggtg atgtggattt ttcgaatggt
    22081 ctgctaccac tgccatataa aggctatcta gtttagaaag tgccattgaa aaactccttt
    22141 gtcttttgta gggcatcgac tagtttgtcg caatctgcct tggtattgta gatataaaaa
    22201 cttgcacgag ctgttgctgg gacttccaaa tactgaagca agggttgcgc acaatggtga
    22261 ccagcacgaa cagccactcc ttcataatcc agagccgtcg caagatcgtg aggatggaga
    22321 tcacctaggt taaaggcaat aacacccgaa cgttgagcca aatcctgaga accgtaaatg
    22381 gtcaatccct caattgcctg cagttttgga tagacgtacg caatcaattc ctgttcatga
    22441 gcttcaacgg catccatacc aatcttttcc agataatcaa ctgcagtcgc aagtccaata
    22501 gctcctgcca tatttggcgt tccagcctca aatttccaag gcaattcctt ccaactagca
    22561 aattgctcgt agacaaaatc aatcatctcg ccgccaaatt ctactggaga catttgctca
    22621 agatactttt ctttgccgta aaggacaccg ataccagtcg gaccagccat cttgtgaccc
    22681 gaaaaggcga aaaagtccag atccaagtcc tggacatcaa tcttcatatg aggtgtagat
    22741 tgagcaccat ccactaccat aattgcccca acttggtggg ctaattgagt gatttccttg
    22801 atcggattga ccacaccaag aacattggag gcatgagcta gggaaacaaa tttaacctta
    22861 tcagtcaatt tagctcgcaa atcctccata tccaaggcac cgtctttaag atagacatag
    22921 acaagctctg ctccagtctt tcgacaagct tcctgccatg gaatgatatt agaatggtgt
    22981 tccattactg aaatcaagac ccggtctccc tcagcgagaa tttcctcagc aaagcgtgcc
    23041 acccagttaa ggctggttgt cgttcctctg gtaaagagaa cttcctttgt agagcctgca
    23101 ttaataaact tacgaatggt ttcacgagca gcttcataag aagctgtcgc tcgttccgct
    23161 aaggtatgga caccacggtg aacattggca ttgtcctgct catagtaact gttaatagct
    23221 ttcagaacta ctagtggttt ttgtgtcgtc gcagcattgt ccagatagac cagaggttca
    23281 tcattgacaa tctgatctaa aattggaaaa tccttgcgaa tcgcttctac atctaacata
    23341 ggcttcccct tagcgttttg acaatttctc ttcgatagtt gcaatcattt catcacgaac
    23401 ttccttgact ggaatctcca cgataacaga tccaaggaaa ccacgaacaa ccaaacgctc
    23461 tgcagttgcc ttatccaatc cacgactcat gaggtaatac atgtcttctg gatcaacttg
    23521 tccgatagac gctgcgtgtc ctgcagtgac atcattttca tcaatcaaaa gaattgggtt
    23581 agcatctgaa cgcgcttggt ctgaaagcat gagaacacgg ctctcttgtt gcgcatctgc
    23641 tcccttagca cccttgatga tgtggccgat accattgaaa gtcaaagttg ctttttcaag
    23701 gataacccca tgttgtagga tatttccgat agagttgcag ccatagttag ttacacgagt
    23761 atcaatccct tgtacctgac gaccacttga aagagctaca accttgaggt cagcatggct
    23821 accattacca atcaagtcac tatcaaaatc agcaacgaca tttccttcgt tcatgacacc
    23881 gatagcccag tcaatacttg catcgttgcc taatttacca cgacggctaa tgtaggcagt
    23941 gacgttttca cctagacggt cgatagcagc aaacttgact tgcgcaccag aacgtgcaat
    24001 cacttccact gtgatattgg cagttacttt gtcacttcct tcaccgcgtg actctaaacg
    24061 ctccagataa ctaatcttag aatttttacc agcgataatc ataatatgct tgttaaacgg
    24121 cacattgcta tcgctatctt ggtagaaaat tccttcaatt ggctctgtga tttctacgtt
    24181 atctggaata tagagtacag caccactgtt aaagtaagct gtgtggtaag ccgccaactt
    24241 gtcatcatca tacttaacag atgacatgaa gaattcttcg atcagctctg gaatttcttc
    24301 taaagctgag tgaaagtctg tgaagacaac accctgttca gctaactcaa ctggagtttg
    24361 ttcgaaaaca gtttgagttc ctacttgcac caacttcaag tgatgatcta aagctgtgaa
    24421 atctggaaca tttgctgatg gctcattttc tgtaatcgtt ccatcaccca gattccaacg
    24481 gtggaatttg acacgctcaa taactggtaa ttccaaagtc tcaatcttgt caaaagcttt
    24541 ttgacggaga tcagccaacc agcttggttc agcgtgcatt tctgaaaaaa gtttaatatt
    24601 ttctctagtc atttacttct cctaaaagat acgagggaat tacaattctt ccttgtagtc
    24661 gtagccaagt tcttcagcta gttttgcgta tccttcacgt tccaaacgcg cagccaattc
    24721 tggaccacca gaaaggacaa cacgaccttc catcatcacg tgtaccacat caggtgtgat
    24781 atagttcaaa agacgttggt agtgagtgat gatcatagca ccaaaacctt caccacgcat
    24841 ggcattgaca cctttagaca caactttaag agcgtcaata tcaagacctg agtcaatctc
    24901 gtccaaaaga gcaaatgttg gctccaacat caaaagttga agaatttcat tgcgtttttt
    24961 ctcaccacca gagaagcctt cgttgaggta acgctctgcc atttcttctt tcatgttgag
    25021 caattccatt ttttcatcta gcttagtaat aaactcacga actgaaatct tctcatcatc
    25081 ttctttaccc gcattcatag cggcacgaag aaactcagca ttggtaattc cagggatttc
    25141 tgatgggtat tgcatagcaa ggaaaagtcc catacgcgca cgctcatcca cttccaactc
    25201 aaggatgttt acgccatcaa acaaaacttc acctttagtt acttcatagt ttggatttcc
    25261 catgatagcg gcagaaagag tcgatttacc tgtaccattt ggtcccatga tagcggcaat
    25321 ttctcctgtt ttcagggtca ggttaacccc ttttaaaatt tcttttcctt caatctcaac
    25381 gtgaagatct ttgatctcta ttactgacat gatagttcct ttctttttca aaacttttac
    25441 agtacttact agaaaaacgt ctgatttccc cagaaataga gcaaaaattc tataaatata
    25501 cttttctagt ataacaaaaa aaagcctaaa aggctttgat tttgtctgga agctgagggc
    25561 tagtctttcc tattaaaatg ctgatcgatg acatcaacaa ttttacccat cacataactg
    25621 actcggaaat ttctaaagag taaaattgcc caaaaggctg ccataatata gcggccagtc
    25681 atccaggctt cattgaaaaa ataggtctca gcagctgtaa atagcgccat aataataaat
    25741 tgttgtttat tcataaactt attgtatcat gaaatctttc tttagtcttc ctctaccttc
    25801 actttatcag ccaaaaattc aaatccttct ggaatcaggc tttcttctac ttctttttca
    25861 gtttgagaag atttggcttt ggctgaaaag gctgcgcgaa cttctttcca ttcctccatg
    25921 gaaatagcta aaatctcagg tgaaaaacct gccgcctgac tgaggatatt accaaacatg
    25981 gtattgagat tgtctcgttt catagtttga ccagcattga agttagactc aaaagcaaga
    26041 atagcatggt gttcattggc agcaaccggt tgagaaccaa ctagcagagc cttgtccggc
    26101 ccacctagac tttcaattac ctctccccag gcattctgca aacgaattag attttgacgt
    26161 gctaaatcag gattttcgac ggcctcttgt aagatagatt gcactttatt gcgatcgaca
    26221 cgatagactg ttttgcccgt agctggtcga ctaggagctg gtgcaacttg tttaggaacc
    26281 gcacctgcat tagaaagctc ttgtttgaga cgggcaactt cctgtctcag cgtagcaatt
    26341 tcattttcaa ccgctcctga tagagctggt tcgggcttga tttccgccaa acagacggtc
    26401 atcatttcag cataaatctt gggctgcaaa ctagacttaa tatctgctaa attcactgtt
    26461 gctaagcgaa tcatttcaaa cagatttttt tgaggaagtg ccaaattttc tacaaagact
    26521 gaactatgat gagtattttc tccccctgtt tgaacaatta acaagtctct taaatagtgc
    26581 aaaagatcgg tcacaaaacg agtcatgctc ttaccattgt caaaaagaag attcaagcaa
    26641 gacaaagctt tgggaacatc ctgttgagac aaggccgcca cataatcatc caaggctgat
    26701 aggctaatgg tgccagtaat ttcttcagag atagcagtcg tcagctcatt tccctgtgtc
    26761 aaactcaggg cttgatccaa aatagacaag gcgtcccgca ttccaccttc cgcccgtctg
    26821 gcaatgattt ccacagcctc tggttcagaa ctgatatttt ctttttctaa gatatagtga
    26881 atatgttcct taatatcctg tgtcttaatt gatttaaact caaaacgttg cacacgggat
    26941 agaatagtag caggaatctt gtgcaattca gtagtggcca aaataaagac tacattctgt
    27001 gttggttctt ccagcgtctt taggagggca ttaaaagccc ctgtagacag catgtgaacc
    27061 tcatctatga tataaacctt ataacgagca aggctaggcg cataggtaga tttatcacga
    27121 atttcgcgaa tttcatctac cccattatta gaagctgcat ccatttcaat gacatcttct
    27181 aaactaccgt ccgtcactgc ttgacaaata tagcagttat tgcaaggttc gccacccact
    27241 tgattgggac agttcatagc cttggcaaag attttagcaa cactggtttt tcccgttcca
    27301 cgaggaccag aaaaaagata agcgtgactt attttctctt gctccaccgc ttgtttaaga
    27361 gtcttagcca caacttcttg accaactaac tgggagaagt tttgacttct atattttcga
    27421 taaagtgctt gatacattaa gatttttcct caaacatcgt aaagtcccat gctgtctttt
    27481 caagcaaaat agcgacaaat tgttccaaat aatctcgatc catagcatcg taatcctcaa
    27541 tctctgaaga atccagatcc agaactccaa gtaactgacc attcttcatc atcggcacca
    27601 caatttcact tttagctaga ctatcacaag aaatatagtt gagataggtc gtcacatctc
    27661 caacaataac agtttcctga aagtgagctg cctcaccaca aacacccttg cctagtgcaa
    27721 tacggatgca ggaaacacct ccttggaagg ggcctaaaac caattccttt ccatcgaaca
    27781 aataaaagcc tgcaaatacg gtattaggaa aacgtgattt tatgagagca ctggcgttgg
    27841 aaagattagc caaaacattg gtttcgcctt ccaataggaa ggacaattct tcatttaaca
    27901 tttgataacg tgattgtttt tctgatttta acatagaact attatatcaa aaaaggagca
    27961 gagacaaaag aaaaatccct tgtttagtaa acaaaggatt ttgggctcta taatatttgt
    28021 agtgggtaaa tcccctatgg atattatgga gcctattttt gtgtagaaaa aaagtcccat
    28081 atgacctata atgaaaagcg acaaaacaac tcattagaaa gaatcatatg gaataattac
    28141 attttatcac aaaattacta gacattaaag accctaatat ccagatttta gacatcgtca
    28201 ataaggatac acacaaggaa atcatcgcca aactggacta tgaagctcca tcttgtcctg
    28261 agtgcggaag tcaaatgaag aaatatgact ttcaaaaacc ttctaaaatt ccttatcttg
    28321 aaacgactgg tatgcctact agaattctcc ttagaaagcg tcgtttcaag tgctatcatt
    28381 gttctaaaat gatggtcgct gaaacttcta tcgtcaagaa gaatcatcaa attcctcgta
    28441 ttatcaacca aaaaattgcg caaaagttga ttgagaagat ttctatgacc gatattgctc
    28501 atcagctggc catttcaact tcaactgtca ttcgaaagct caatgattct cactttgagc
    28561 atgatttttc gcgtcttcct gagattatgt cctgggacgt tgaaacagtc cggggagtga
    28621 ctgtttcaat cgggagatgg agatgagctt tattgcgcaa gattttaaca atctcaatat
    28681 catcactgtt cttgaaggca gaacacaagc tgtcatccga gatcactttc ttaaatatga
    28741 tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagtc cttactatga
    28801 cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt ctcccagact
    28861 gtttcactcc cgaatgctaa aatcgttctt gatcgctttc acattgtaca acatcttagc
    28921 cgtgctatga gtcgtgtgcg tgttcaaatc atgaatcagt ttcatcaaaa atcccatgaa
    28981 tacaaggcta tcaagcgcta ctggaagctc atacaacagg atagccgtaa actgagtgat
    29041 aagcgatttt atcgtcctac ttttcgtatg catttaacca ataaagagat tttagacaag
    29101 cttttgagct attcacaaga cttgaaaca
//
LOCUS       DAVLMQ010000021        26775 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000021 DAVLMQ010000000
VERSION     DAVLMQ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26775
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.021"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..172
                     /locus_tag="VXF95_001136"
     CDS             <1..172
                     /locus_tag="VXF95_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1081694.1"
                     /translation="NKEVAFYLTSIIRQALKNTEYKDQISSTVLPDIKIKLPIDSRGT
                     PDWNYMERYRDR"
     gene            138..451
                     /locus_tag="VXF95_001137"
                     /pseudo
     CDS             138..451
                     /locus_tag="VXF95_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829800.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1135..1296
                     /locus_tag="VXF95_001138"
     CDS             1135..1296
                     /locus_tag="VXF95_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081695.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            1388..3067
                     /locus_tag="VXF95_001139"
     CDS             1388..3067
                     /locus_tag="VXF95_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HEV1081696.1"
                     /translation="MSKEKIKVYLYTRVSTSIQIEGYSLEAQKSRMKAFAIYNDYEIV
                     GEYEDAGKSGKSIEGRIQFNRMMEDIKSGKDGVSFVLVFKLSRFARNAADVLSTLQIM
                     QDYGVNLICVEDGIDSSKDAGKLMISVLSAVAEIERENIRIQTMEDCIQKAREGKWNG
                     GFAPYGYKLEDGKLFINEEEAVAIRTIFDQYVNTTIGANGISKYLENHGIRKIPRQNG
                     KNPLFDAGLIRKILKNPVYNGKIAFGRRTLEKVHGTRNEYKQVEQDEYLISEGIHEAI
                     VSDEVWQAAQVKLKSQAKKYEHVNKGKDTRTHLLSGIVKCPICGVGMFGNKCIKKKKD
                     GTKYKDFYYYGCKHRQMIRGHKCTFSKQIREELLDDAVAEVIVKIVSNPKFASMMQEK
                     INMKVDTSEIEKEIDNYQKELRKSHSTKFKLIEEIDNLDVEDKHYKRRKQDLDDRLYR
                     MYDKIDELESSLIDAKAKKQTIEAEKLTGDNIYKVLIYFDKLYKVMNDVERRQLISAL
                     ISEIQVYEEKQSNGQWLKSITFKLPIIEENLNIDLDNDEQVECVSLLEKRS"
     gene            3335..3901
                     /locus_tag="VXF95_001140"
     CDS             3335..3901
                     /locus_tag="VXF95_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081697.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            4223..4411
                     /locus_tag="VXF95_001141"
     CDS             4223..4411
                     /locus_tag="VXF95_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1081698.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            4473..5231
                     /locus_tag="VXF95_001142"
     CDS             4473..5231
                     /locus_tag="VXF95_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1081699.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            5289..5750
                     /locus_tag="VXF95_001143"
     CDS             5289..5750
                     /locus_tag="VXF95_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1081700.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            5784..6143
                     /locus_tag="VXF95_001144"
     CDS             5784..6143
                     /locus_tag="VXF95_001144"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1081701.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            6255..7139
                     /locus_tag="VXF95_001145"
     CDS             6255..7139
                     /locus_tag="VXF95_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1081702.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            7302..9041
                     /locus_tag="VXF95_001146"
     CDS             7302..9041
                     /locus_tag="VXF95_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV1081703.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            9316..9618
                     /locus_tag="VXF95_001147"
     CDS             9316..9618
                     /locus_tag="VXF95_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081704.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            9674..10102
                     /locus_tag="VXF95_001148"
     CDS             9674..10102
                     /locus_tag="VXF95_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081705.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            10160..10769
                     /locus_tag="VXF95_001149"
                     /pseudo
     CDS             10160..10769
                     /locus_tag="VXF95_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000662948.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Type 1 glutamine amidotransferase-like
                     domain-containing protein"
     gene            11051..11298
                     /locus_tag="VXF95_001150"
                     /pseudo
     CDS             11051..11298
                     /locus_tag="VXF95_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335280.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside phosphotransferase"
     gene            11403..11705
                     /locus_tag="VXF95_001151"
                     /pseudo
     CDS             11403..11705
                     /locus_tag="VXF95_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            11861..13090
                     /locus_tag="VXF95_001152"
     CDS             11861..13090
                     /locus_tag="VXF95_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HEV1081706.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            13110..15806
                     /gene="ppc"
                     /locus_tag="VXF95_001153"
     CDS             13110..15806
                     /gene="ppc"
                     /locus_tag="VXF95_001153"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HEV1081707.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATSLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYETILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    15889..16106
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            16219..17223
                     /locus_tag="VXF95_001154"
     CDS             16219..17223
                     /locus_tag="VXF95_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1081708.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNVTGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            17292..18158
                     /locus_tag="VXF95_001155"
     CDS             17292..18158
                     /locus_tag="VXF95_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081709.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            18155..18913
                     /locus_tag="VXF95_001156"
     CDS             18155..18913
                     /locus_tag="VXF95_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081710.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQATIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            19003..20763
                     /gene="dnaG"
                     /locus_tag="VXF95_001157"
     CDS             19003..20763
                     /gene="dnaG"
                     /locus_tag="VXF95_001157"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HEV1081711.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVTFMEAVQILGQRVGIEVEKPLYSEQ
                     KPASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKVIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKTSEIYLMEGFMDVIAAYQAGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VQEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMEGISRPTPITMPIT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEEFERLISQKRRME"
     gene            20766..21875
                     /gene="rpoD"
                     /locus_tag="VXF95_001158"
     CDS             20766..21875
                     /gene="rpoD"
                     /locus_tag="VXF95_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HEV1081712.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            21889..22218
                     /locus_tag="VXF95_001159"
     CDS             21889..22218
                     /locus_tag="VXF95_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1081713.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            22333..23376
                     /gene="cpoA"
                     /locus_tag="VXF95_001160"
     CDS             22333..23376
                     /gene="cpoA"
                     /locus_tag="VXF95_001160"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HEV1081714.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPAVLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            23392..24717
                     /locus_tag="VXF95_001161"
     CDS             23392..24717
                     /locus_tag="VXF95_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HEV1081715.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRIIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLAAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAILEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLQQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            24748..24924
                     /locus_tag="VXF95_001162"
     CDS             24748..24924
                     /locus_tag="VXF95_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HEV1081716.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            24983..25117
                     /locus_tag="VXF95_001163"
     CDS             24983..25117
                     /locus_tag="VXF95_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HEV1081717.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            25181..26491
                     /gene="obgE"
                     /locus_tag="VXF95_001164"
     CDS             25181..26491
                     /gene="obgE"
                     /locus_tag="VXF95_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HEV1081718.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYSRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEDFKKKLSENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEEAYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            26501..26659
                     /locus_tag="VXF95_001165"
     CDS             26501..26659
                     /locus_tag="VXF95_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081719.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT         8802 a         4254 c         5819 g         7900 t
ORIGIN      
        1 gaataaagaa gtagcattct atttaacttc aattattagg caagctttaa aaaatactga
       61 atataaagat caaatatcta gcacagtatt gccagatatc aaaattaaat taccgataga
      121 cagtagaggt actccagatt ggaattacat ggaaagatat agagatagat aaagagagag
      181 ggagagatag ataaaaagtc cacccccatt tttttatgga gaattcaaaa atgtaaggtt
      241 aagcaaagaa gaatataaaa atctaaaaga aaaattaaac tcacacacag atataatgat
      301 aaataaacta tccagataca tggaaagcag tggtaagacc tatcaaaacc actatgtgac
      361 aatcttaaaa tggtatgaag aagataaaga caaactaaga cagaaaggtt taaataaaaa
      421 aatgaattat gatgtaggag aatctttata gataaaaaga ggtggaaagg cactattaaa
      481 gactttaagt ctaaaaaggt atcaaagtat gccagagata aaaaaatata aatatgacac
      541 tttaaaggtg attagaaaat taaagaaatg ctagaagact tttagatgac agttaccaag
      601 agggtctaat tttcactgct acttatgcag tgggaattgg acctttttat ataagcaaat
      661 tctatttcaa aattggttac caagaaagac ttcttttcac tgttaagtat aagagggtaa
      721 tttatagaat tttgttacat taagataaat attttctgat ggtcaaattt taaaaagatt
      781 aataattctc gataaatttt gaaccttaac aattgaatag accaagacaa gacgttaatt
      841 atttttggag cgtaataacc tatccgtcaa gatctttcgg ctgaataatt cggcaaaaaa
      901 agttctgcta agtaaaaaga aagtgagcga taagtaagag tttgaatata gggagggata
      961 ccctatccgc tatgaagaaa atgaggataa tgatacttct aaggttgaag ccggctcatc
     1021 cggaatagag gcggaggtga gattcctatg ttgctaatcc aaagcacttg tcaatgtcaa
     1081 aaaacttaat taaacaaata attattagat ataaaacttt agaggaggta tatattggac
     1141 aatgactgga atggattggc tgatttaata gcaaatctga ttgcaaaata tgctggtgct
     1201 ttagatttag ataatctacc cgatccaacg ccagcaaaaa atcaagagat gaaaaatagt
     1261 tttgacatgg caaaaacaca aattgagacg gactaataaa agtgttataa tatacttgaa
     1321 atgatagtcc aaacttaaat taaaaaaatt atatatgata tagaaaaatt atattgaggt
     1381 taatactatg tcaaaagaaa aaataaaagt atacctctat acacgagtat ctacgtcaat
     1441 acagatagag gggtattcgt tagaggcaca aaaatcacga atgaaagctt ttgctattta
     1501 caacgattat gaaattgttg gagagtatga agatgccggg aagtctggca agtctattga
     1561 aggtagaata cagttcaatc gaatgatgga agatataaaa tctggaaaag atggagtatc
     1621 ttttgttctt gtgtttaagt tatcaagatt tgcaagaaat gccgctgatg ttctttctac
     1681 acttcagata atgcaggatt atggagttaa tcttatctgc gttgaagatg gcattgattc
     1741 atctaaagat gctgggaaac taatgatttc tgttttatca gctgtggctg aaatagaaag
     1801 agaaaacatc cgtattcaaa caatggaaga ttgcattcaa aaagcaaggg aaggaaaatg
     1861 gaatggtggc tttgctccgt atggatataa acttgaagac ggcaagctgt ttataaatga
     1921 ggaagaggca gttgcaataa gaacgatttt cgaccagtat gtaaatacta cgataggagc
     1981 caatgggata tctaaatact tagagaatca tggaattaga aaaatcccaa gacagaatgg
     2041 taagaatcct ttgtttgatg caggtcttat aagaaagata ttaaagaatc ctgtatataa
     2101 tgggaaaata gcatttggaa gaagaacttt agaaaaagtt catggtacaa gaaatgaata
     2161 taagcaggtt gaacaagatg aatatctaat atctgaaggg atacatgaag ctatagtttc
     2221 cgatgaagtt tggcaagctg ctcaggttaa gctaaaatct caagcaaaga aatatgagca
     2281 tgtgaataaa ggaaaagata cacgcacaca cttgctttct ggaattgtaa aatgcccgat
     2341 atgtggagtg ggaatgtttg ggaacaagtg tatcaagaaa aagaaagatg gcacaaagta
     2401 taaagatttt tattactatg gttgtaaaca taggcagatg ataagaggtc ataagtgtac
     2461 attcagtaag caaattagag aagaattgtt agatgatgct gttgcagagg tgattgtcaa
     2521 gatagtaagt aatccgaaat ttgcttctat gatgcaagaa aaaatcaaca tgaaggtgga
     2581 tacctctgaa atagaaaaag aaatagataa ttaccaaaag gaattgagaa agagtcattc
     2641 tacaaagttt aagctaattg aggaaataga taatttagat gttgaagata agcactataa
     2701 gagaaggaaa caggatttag atgatagact atatcgtatg tatgacaaaa tagatgaatt
     2761 agaatcatca ctaattgatg cgaaagcaaa gaaacagact attgaagctg aaaaacttac
     2821 aggagataac atatataagg ttctgatcta ttttgataag ctctataaag tcatgaatga
     2881 tgtagagcgt aggcagttaa tttcagcttt gatttctgaa attcaagttt atgaagaaaa
     2941 acaatctaac ggacaatggc taaaatccat tacttttaag ctaccaatta tagaagaaaa
     3001 tctcaacata gatttggaca atgatgaaca agttgaatgt gtaagtttat tagagaaacg
     3061 tagttaatcc tcaaaaggtt ccccaaactt tttgagtccc actgacgcat cacgctgagg
     3121 cggtatcact gcttgtacga gttgaagcat cagcgaagta aaagtagatg ttcagccaat
     3181 gcgacgaggt gagaccgaag gtcgataagg tgtgttctgg gtataggact cgtaaagtaa
     3241 gtaggaaata tgatgagatg atacagagag cctgaattgg tcaggtgacg tgcttattta
     3301 cattagcctg ataatgaaaa tggagagatt atcgatggtt atattggaat tgtaccaaaa
     3361 tgattattct aaagatttag tagcatttga ttccatagaa gatgggaaag cctttgtggc
     3421 tcaaatcccg ggatacactc tggaaacaga agatggtttt gaagtggagt attttaatcc
     3481 taaaaacata ccggattata tggaaattat ttttaacgga aatattgttc ctttatctaa
     3541 atttatgttc gatcctgagg aaaatgtaaa cattatttgg aaagagattt caaatttatc
     3601 cctcaaaaat gatagagtga tcgaaggata ttcaaaaatt gatgcatatg tcgttaacaa
     3661 ccatgaagtt aaagcctatg tcgaaacaag agaaacgaac tatcgtaaag caaaagactt
     3721 cttagaaagc cgcggatatg aaatcgacag aagctttttc ggaagtgaag acggtgaagc
     3781 gattctttac agaaaaaaag ggatcgaagt ttggcatttc ttgtgtcact tagacccaat
     3841 gtttgtagag attgaagatg tagaaggata tgttaaagaa gaagttggag agattcaata
     3901 gtcaaccaaa gttccttgtg agtatatacc tttgctagta aaagagtcaa aacgttataa
     3961 cgaagggggg gaagaaaacc cttgagtgta agtctttttc ttgtttagag ggaaagtatt
     4021 agagtagccg ctcataattt atactagatt tgataactga tttgagacag attttatttc
     4081 tataaatatt gtgaaaattt tttaatacca aagatttaaa gttactgtgt taaaaatcct
     4141 ctccactttt aaactaatgt attataaaag ccagttgaca caagtgttac acctgtgata
     4201 gaattaactt gaggtgatga aaatggcaac cgataaaaat agaataatga ttagcttgga
     4261 tgataaaaat ctagagaaac ttgaaaattt agtagaagat gctagagata gaaggggaat
     4321 gcgactaaca aagtcccagg ttattgaatt actcctaaat accgttgatt atttcgatga
     4381 tattatgggg gctatttact caaaaaaata agagcaaaat tgctattatt ttttacaaat
     4441 tggtgtaaca ctagtgatat aggagtgatg aaatggttgt ttatattaga caaagtaaat
     4501 taccaagtga ggtttcaatt aataaataca atgctcaagt aggtgcctac ttacaaggag
     4561 aagaagctgt tttatatcaa tctttttctg aaataaaaga gttaacaagt gaagatatag
     4621 ttgtagatta tataatggag actagagcat tactaaaaat gatgggctta aacgttccgg
     4681 ttcatgacta tcctattgag cttaaagagt tttatggtcg aaagatttat gctggtattt
     4741 taggagagat tgtgaatata cctgataatt ggggaaaatt tattaagcct aaagctggtt
     4801 caaaagtctt tactggaaga gttgttaatg gaacccatga tttaataggt attggtctac
     4861 ctttcgacta tcctatatgg attagtgagg ttgtagaatt catagctgaa tggcgttgtt
     4921 ttgtgttaga tggtcgcgta ttagatgttc gaccctatac aggtgattat catgcacaat
     4981 ttgatgcaag tgtaattgat gaagcgatat catgttggaa agatgcgcca atagcttatg
     5041 gactagatat cggtgttact cgcgatggca gaacacttgt tgttgaagta aatgatggtt
     5101 atgcattggg aaattatggc ctatctcctt taaaatcaat caattttcat agagctaggt
     5161 ggaaagaaat ggtaaaaccc tattttgaaa aaaatgaaat ttttaaaatc caacaggatg
     5221 ttgttttcta aaataaatat ggtatataac caatataaaa agcatcaaaa tgaacaagga
     5281 ggaatctgat gcttggagca attattggag atattgtcgg ttctgtttac gaatggaaca
     5341 atatcaaaac aaaggacttt cctttatttc ggaaggactg cttttttaca gatgacacgg
     5401 ttatgacctg tgctgttgca gaagcaatta tgaatggtgg acaaaaagac gacttcattg
     5461 acgcgatgaa gaaatatggc agaatgtatc cgaatgctga ttacggtgct cggtttaatg
     5521 catggctaaa cagcgataac cgtgagcctt ataatagctt tgggaatgga tcagctatgc
     5581 gtatttctcc atgtgcttgg atcatggact gtggttttta tgcgaaaact ggtatatggc
     5641 catcatctag aggacttacg agtctttctg cagaggtaac tcataatcat ccagaaggtg
     5701 tcaaaggcgc tatggctaca gctgatgcta tctttctatg tcgtttttaa tttggtggtt
     5761 attgtagaga gtacgagtaa tcaattaacg acaatcctat agagtgtaaa agacgaatta
     5821 aggattatat agaaaaagaa tacgattaca atctatctca aactttagat gaaatccgtc
     5881 ctaactatcg ttttaacgaa acatgtcagg aaactgtccc tcaagccatt atcgcctttc
     5941 ttgaaagtag agacttcgaa gatgcgataa gaaatgccat ctcacttggt ggcgacagtg
     6001 atactctcgc agcaatcact tgtagcatag cagaggcagc ttacggtatt cctgattgga
     6061 tcaaggataa ggcctattct tacttggatg aacccttaaa ggatgtagtt aggcgatggg
     6121 aaaatagaat aaaagtgtat taatctccag tacgtcagat ttctcttttc tgtattttca
     6181 ttgtataata ggattacatt tacttgcata cgacgaaatg taaacatttc tatttaaaat
     6241 taaggataaa atcaatgaaa aaagcaatgg taattatcaa ccctacttct ggtggcgaga
     6301 aggctttgga ttacaaagaa aagctggaga ataaagcaaa agaatacttt gaatatgttg
     6361 aaaccaaaat taccgaaaaa gcgctggatg caacacattt tgctgaagaa gcttctcgtg
     6421 agcagtatga tgcagtggtt gtgtttggtg gagatgggac tgtcaatgaa gtcatttcag
     6481 gtattgatga gagagactac attcctaagt tagggattat cccaggcggt acgggtaacc
     6541 tcattacaaa acttttggaa atcaatcaag acatcgatgg cgcaattgac gaactggatt
     6601 ttgatttaac caataagatt gatatcggta aagcaaatga caactatttt ggttatatct
     6661 ttagtatcgg ttctctgcct gaggcgattc acaatgttga aatagaggac aaaacaaaac
     6721 aaggtatttt agcctatgct gtaaatacta tgaagtctgt catgacagat caggtcttta
     6781 acattaaggt tgagacagaa aatggaaatt atgttggtga agctagccat gttttggtcc
     6841 ttttgacaaa ttacttcgct gataagaaaa tctttgaaga aaacaaggac ggctatgcca
     6901 acattttgat tctgaaagat gcctctatat tctccaaatt atccgtcatt cctgatttat
     6961 taaaagggga tgttatcgca aatgataata tcgagtatat caaagcgcgt aatattaaaa
     7021 tctcttcaga tagtgaattg gagtcagatg ttgacggaga taaatcagat aacctacctg
     7081 tagaaatcaa agtcctagct cagcgagtag aagtattttc aaaaccgaaa gaggattagt
     7141 atatagagaa agcctttttt aaggcttttt gtatacttta aaagatagtt cctttaacaa
     7201 cggacattcc ttgcaaatag ttcacaaaaa tagtatactg gattcattga gtttgaaaac
     7261 gtttgcgtaa aatttgaatg aatactttag gagataaatt gatggaattg agtgctattt
     7321 accataggac tgagtcggag tatgcctatc tttataagga taagaaactc catattcgaa
     7381 ttcgaactaa gaaaggggac attgaaagca tcaacttgca ctatggggac ccttttatct
     7441 ttatggagga gttttatcag gatacaaaag aaatggtcaa gataacttct ggtaccttat
     7501 ttgaccattg gcaggttgaa gtgtcagttg actttgcacg tatccagtat ctttttgagc
     7561 tcagagatac agaaggtcaa aatattttgt atggcgataa agggtgtgtg gaaaattctc
     7621 tagaaaatct tcatgcaatt gggaatggat ttaagttgcc ttatcttcat gagattgatg
     7681 cctgcaaggt tcctgactgg gtttcaaata cggtatggta tcagatattt cctgaaagat
     7741 ttgccaatgg caatgctcta ttaaacccag aagggacttt agactgggat tcatctgtca
     7801 cacctaagag cgatgatttc tttggtggtg atttacaggg gattattgat catatggatt
     7861 acttgcaaga cttgggtatt actggactat atctttgtcc catctttgaa tctacaagca
     7921 atcacaagta caatacgaca gattactttg aaattgaccg tcattttgga gacaaggaga
     7981 cctttcggga actggtggat caagcgcatc atcgtggcat gaaagtcatg ctggatgcgg
     8041 tatttaatca tattggttcg caatctcttc aatggaaaaa tgtcgtcaaa aatggtgaac
     8101 agtctgctta taaggattgg ttccatattc aacaattccc agtgacaact gaaaagctag
     8161 ttaataagag agacttaccc tatcatgttt ttggtttcga ggactatatg cctaagctaa
     8221 atacagccaa tccagaggtc aagaattatc ttttaaaggt tgcgacttat tggattgaag
     8281 agtttaatat cgatgcttgg cgtttggatg tggctaatga gattgaccat cagttctgga
     8341 aggattttcg taaggcagtt ttagctaaaa atcctgatct ttatatccta ggagaagtct
     8401 ggcatacatc tcagccttgg ctaaatggag atgagttcca tgccgtcatg aattatcctt
     8461 tatctgatag tatcaaggac tatttcttac gaggaattaa gaagacagac cagttcatcg
     8521 atgaaatcaa tggagagtct atgtattaca agcagcagat ttcagaggtc atgtttaatc
     8581 tcttggattc acatgataca gagcgaatcc tgtggacggc caatgaagat gttcaactgg
     8641 ttaaatcagc cttagccttt ctctttttac aaaaaggaac accgtgcatt tattacggaa
     8701 ccgagctagc cttgactgga ggaccagatc cagattgtcg tcgttgtatg ccttgggaac
     8761 gtgtatcaag tgacaatgat atgctgaact ttatgaagag gctgattaag attcggaaat
     8821 acgcgtcagt aatcatttcg catggcaagt atagccttca agaaatcaaa tctgatctag
     8881 tagctctgga atggaaatac gaaggacgga tcctcaaagc aatattcaac caatcaacag
     8941 aagattatct tttagagaaa gaagcagtag cactagcaag caattgccaa gaattggaga
     9001 atcagcttgt catctctcca gatggatttg tgattttcta aaaactagtt gatgaagatt
     9061 atggtacatt tcatatctta tatagtataa taaggctagt tactaaactt gtaaaggaga
     9121 acttaaatga attgtagagg acacgaaaca agacaaagaa ttgttagaga ttttgaagtt
     9181 tagcctaaag cacatattaa gctgttagca aatcaacaaa aacatagtga tgcaggagca
     9241 actattgaag atgaatatta tgtatttatc gctgagagta aaattgatgg caagaaggaa
     9301 gttattcagt gttgcatggg tgcggcaagg gattttttag aactaattaa tcacaaaggg
     9361 ctacctcttt ttaatccgct tgtaggtgat tctcatgtaa ataatagaca agaatatgac
     9421 aatacaggga gtggaaattt acaacctgaa aagtggaatg aaactgcaaa gcagctttat
     9481 aatgttataa tgtggttgat tattttatgg aatgctaagc cggatacacc tttatttaat
     9541 tttaaagacg aagtaattaa gtataaaaca tatgagcctt ttgaaagcag tataaaattg
     9601 gtatcaatca atgagtaaca aagtatcagc atgattcgaa acatttactt gtaatttgcg
     9661 gaggaacatc aatatggatg gaataacaaa agattttata aaaacggcta aactaatgaa
     9721 acaattatgg ccccaattga ccgataaaga agctattgat gaagtaaaaa aatatacgaa
     9781 tggcaaaaat actgcaatct ttactgaagt tgaaggtgac acaattgtag gtctagcact
     9841 atgttcactc agatttgatt atgttgaagg ttgtaaatat agtcctgttg gattcttaga
     9901 agggattatt gttgacgagg aatatcgttt aaaggatatt gctaaaaatc tctgtacaaa
     9961 atgtgaggaa tgggcgaaaa ataaaggatg taaggaattt gcaagtgact gtactttaac
    10021 gaatacggat tctataagat ttcatctcaa tattggattt caggaggcaa atagaattat
    10081 tcattttaag aaaaaattat aatttagaaa cgtgaataaa cttgtttaaa ctttatgtat
    10141 ctttagaaag tgtgttaact tgaaagaaca aatttttttg atgggtggga atcccccaat
    10201 gaagaaatat agtattgttg ataaaattgt attatcaacc aagattaaaa gaattatcat
    10261 ttttacagtt tttcgagaaa attgggaacc gtacatgaaa aagtacacgg aagtttttca
    10321 aagtcaattt cctaatctaa acattgatta cttgctcctg gacactgagc agattgatct
    10381 tgatagctat ctagatgctg acataattat catcggtggt ggaaatacgg aaaaatatat
    10441 tgctaactta tgttaatcag gagttcaaaa gttatatcga tcatatgctt aataaagagg
    10501 caaaaattat aggattttct gcaggagccc tactattagg agaaaaagtc tatgtctcac
    10561 ctaatgataa ttcagatcat cagataaaga taaaaaatgg attaggactc tttagtcagt
    10621 ttttaattag tgtccattat gattcctgga atgataaagc aaataaggat agagctgaag
    10681 aactcgttaa tgttcccata attccactaa atgatcattc ttgtcttgta ttggataaac
    10741 ttggaaacat catagagaaa attgactaac tttcataatg taaaaatgga tctaggaaat
    10801 aaaagtgtag acgaactgga taggttacta gtgaaaactg caaaaagtgt tgtaaagtga
    10861 atcggagtgt gcttgatgga ttttagtagt aagatagcca taaataaggg ctggtcagat
    10921 gataaaaaat attgtgtgac agatcaaaat cagtaaaaat atttcttgcg tgtttctgat
    10981 aagtcgaagt tagattataa aaaaatttga atttgatatg atggagaaag tagcttctct
    11041 tggagttccg atgtgtaaac caattagcat tgaactctgc gatgacgaag tacattcttt
    11101 acacgaatgg atagacggaa gagatgcaat agatagcatt ttagcttatt cagaaaacca
    11161 acaatacaca tatggtgtag aagcaggaaa gatacttaga aagattcata caattcctgc
    11221 tacagaagtt tgtgaagatt gggaaatttt tttaatctaa aaattgatga taaaatctcc
    11281 aacgaaatga tatggtaagt ccgaaacgct cagtgtgtaa gcttgttgct aaaagcgtaa
    11341 aaaccttgga acgaaaggaa taatagactt cctgcgaaac aaaaatacaa tacaataaaa
    11401 ctatggatga tgaagcaagt aaacaattaa gcgatagccg tttcaagatc cttgtaggtg
    11461 ttcagcgcac gacttttgaa gagatgttag ctgtgttaaa aacagcttat caacgtaaac
    11521 gcgcaaaagg tggacgaaaa agcaaattaa gcctagacga tctccttatg gtaactattc
    11581 aatacatgcg agaatagagc acttatgaac aaattgcggc tgattttggc attcacgaaa
    11641 gcaacttaat ccgtcggagt caatgggttg aagcaactct tattcaaaat ggttttacga
    11701 tttcaaattc tgccttaatt ctgtaaaaac agtaaaattc gaaggattgt aaggtaagag
    11761 tttttttctt tctgaaaaaa tggtataata gcaatcaaaa ctagaaaata aaacggaatt
    11821 tggaacagat ttgtctgtat cctagtagag tggtgatact atgaagatta gtaagaggca
    11881 cttattaaat tattccatct tgattcccta cttgctttta tctattttgg gcttgattgt
    11941 ggtctattcg accaccagtg ctattttaat tgaagaaggc aagagcgcct tgcagttggt
    12001 tcgaaaccaa ggaatctttt ggattgttag tttgatactg attgccttaa tttataaatt
    12061 gagactagat tttttgagaa atgagcgact aatcatttta gttatattaa tagaaatgct
    12121 tttattgttc ttggctcgtt ttattggtat ttcagtaaac ggggcatacg gttggatttc
    12181 ggttgcagga gtaactattc agccagctga gtacttaaaa atcattatta tttggtattt
    12241 agctcaccga ttctccaaac agcaagaaga aatagctact tatgattttc aagttttgac
    12301 tcaaaatcaa tggcttcccc gtgcttttaa tgattggcga ttcgttctcc tagttctgat
    12361 tggaagtttg ggaattttcc ctgatttagg aaatgcgact attttagtct tggtttcctt
    12421 gattatgtat acagttagtg gaatcgctta tcgctggttt tcaaccattc tggcgctcgt
    12481 atctgccact tctgtctttg tcttgaccac tatcagccta atcggtgttg agaccttttc
    12541 aaaaattcca gtatttggct atgtagccaa gcgctttagt gcctttttta atccttttgc
    12601 cgatcgtgct gatgcaggtc accagttagc taattcttat tttgccatgg tcaatggtgg
    12661 ttggtttggt ctaggtcttg gaaactcgat tgaaaaacga ggttatttgc cagaagctca
    12721 tacagacttt gtcttttcta tcgtgattga agaatttggc tttgttggtg ccagtcttat
    12781 tttagctctc ttgtttttca tgattttgcg gattatcttg gtcggtatcc gagcggagaa
    12841 tcctttcaat gccatggttg cactcggtgt cggagggatg atgttggttc aggtatttgt
    12901 caatatcgga gggatttcgg gcttgattcc atctacagga gtgactttcc ctttcttatc
    12961 ccagggtgga aatagtcttc tagtcttatc agtggcagta gcctttgtct taaatattga
    13021 tgccagtgaa aaacgcgcta agttgtaccg agaattggaa aatcaaccaa tgaaccttct
    13081 gttgaagtag gataaagaaa ggatagttta tgtctcttca aaaattagaa aattatagta
    13141 ataaaagtgt tgtgcaagaa gaagtcttga ttctaacaga attactggaa gatattacta
    13201 aaaatatgct tgccccagag acctttgaaa aaataataca gttgaaagaa ttatcaacgc
    13261 aggaagatta tcaaggtcta aaccgtctag tgactagctt atcaaatgat gaaatggtct
    13321 atatttcacg ctatttctct atcttacctc ttttgattaa tatttcagag gatgtggatt
    13381 tagcttatga aatcaatcat caaaataata ttgatcagga ctatttaggt aaattatcta
    13441 caacgattaa attggtagca gaaaaggaaa atgccgttga gatcctagaa cacttgaatg
    13501 ttgtccctgt tttgacagcc catccaacac aagtgcaacg caaaagtatg ttggatttaa
    13561 caaatcatat tcatagtctt ttgcgtaaat accgtgatgt taagttgggg ttgatcaata
    13621 aagataaatg gtacaatgat ttgcgtcgtt acatcgaaat tatcatgcag acagacatga
    13681 ttcgtgagaa aaaattaaaa gtgactaacg aaatcacgaa tgctatggaa tattataaca
    13741 gctccttttt gaaagctgta cctcatttga cgacggagta taagcgctta gcgcaagcgc
    13801 atggtctgaa tttaaaacag gctaaaccaa tcaccatggg tatgtggata ggtggtgacc
    13861 gtgatggaaa tccatttgtt acagcaaaga ccttgaagca gtctgcactc actcagtgtg
    13921 aagtcatcat gaactactat gataaaaaga tttaccaact ttatcgtgaa ttttctcttt
    13981 caactagcat tgtcaacgtc agcaagcaag tcagagaaat ggctcgtcaa tccaaggata
    14041 actcgattta ccgcgaaaaa gagctttacc gtcgtgcctt gtttgatatt caatcaaaaa
    14101 ttcaggcaac taaaacctat ctgattgagg atgaagaagt tgggactcgt tatgaaaccg
    14161 ccaatgattt ctacaaggat ttgattgcca ttcgagattc tctactagaa aataagggcg
    14221 agtccttgat ttcaggtgat tttgtggaat tattgcaggc agtagagata tttggttttt
    14281 acttagcatc aattgatatg cgacaagact ctagcgtcta tgaagcctgt gtggcagaac
    14341 tcttgaaatc agcaggaatt cattctcgtt atagcgagtt gagcgaagaa gaaaagtgtg
    14401 accttctctt gaaagaatta gaagaagatc cccgaattct ttctgcgact cacgcagaaa
    14461 aatcagaatt attagcaaaa gaattagcta tttttaagac ggctcgtgtt ttgaaagata
    14521 agttgggaga tgatgtcatc cgtcagacca tcatttcaca tgcaaccagc ctttctgata
    14581 tgctagaatt agctattctg ttaaaagaag taggactggt ggatacggaa agggcgcgtg
    14641 ttcagattgt tccccttttt gaaacaattg aagacttgga tcattcagag gaaacaatga
    14701 gaaaatatct ttctcttagc cttgccaaaa aatggattga ctcacgaaat aactaccaag
    14761 aaatcatgct tggctactct gacagtaata aagatggcgg ttacttgtca tcatgttgga
    14821 ccctctacaa ggctcaacaa caattgactg ctattggaga tgaatttggc gttaaggtta
    14881 ccttcttcca tggtcgtggt ggtactgtcg gtcgtggtgg tgggccaacc tatgaagcca
    14941 ttacatctca accgctcaag tctatcaagg atcgtatccg cttgacggag cagggtgaag
    15001 taattgggaa taaatacggt aacaaagacg ccgcttacta taaccttgaa atgctagtat
    15061 cggcagctat taaccgtatg attactcaga agaagagcga taccaatacc ccaaatcgtt
    15121 atgaagccat tatggatcaa gtagtggacc gtagttacga tatctaccgt gatttggtct
    15181 ttggtaatga gcatttctat gattatttct tcgagtcaag tccaatcaag gctatttcaa
    15241 gttttaatat tggttctcgt ccagccgctc gtaagactat tactgaaatc ggtggtttgc
    15301 gtgccatccc ttgggtattc tcatggtcac agagtcgtgt tatgttccct ggatggtacg
    15361 gggttggttc aagcttcaag gaatttatca ataaaaatcc agagaatatt gctatcttac
    15421 gagatatgta ccaaaattgg cctttcttcc aatcgcttct ttcaaatgtt gatatggttt
    15481 tgtcaaaatc aaatatgaat attgcttttg aatatgctaa actttgtgaa gacgagcaag
    15541 ttaaggccat ctatgagact attttaaatg aatggcaagt tactaagaac gttatcttgg
    15601 ctattgaagg acatgacgaa ctcttagctg acaatccata tctaaaagct agtctggatt
    15661 accgtatgcc ttactttaat attctcaact atattcagtt agagttgatt aaacgccaac
    15721 gtcgtggaga attgtccagt gatcaagaac gattgattca tatcaccatc aacggaattg
    15781 cgacaggatt gcgtaattca ggttgataat tttcaagagt gaatactaaa agtgaatatc
    15841 aaaaaaattc taatagacta ttgacaagta atttaaaaat gatataattt aaccattcag
    15901 aaaagtaatc atacaaactt tttagagagt ctgtggtagc tgaaaacaga taagtggcga
    15961 tgatgaaaat tgggctgaat gctatttaga atttgaaatt ataaaaattc ggtaagcaca
    16021 ccttacagtg catctcgtta ttgcgagact gagcgatagg gaaattccct ataattgagg
    16081 tggtaccgcg catcgacgtc ctcacacaag ttttttgtgt gaggattttt ttgatggagg
    16141 ttagtatgga aagaaaacga tggcgtcgct tgtttagata agtgaaatat gttaaaggaa
    16201 ataaaaagga gaaacagaat gaaaaataaa cgtttaattg gaattattgc tgcattagca
    16261 gtcttagtag caggaagctt gatttattct tcaatgaata aatcagaagc tcagaataat
    16321 aaggatgaga agaaaataac caagattggt gtgcttcaat ttgtgagcca tccatccctt
    16381 gatttgattt ataaagggat ccaagatgga cttgcagaag aaggatataa agatgatcaa
    16441 gttaaaattg attttatgaa ctcagaaggt gaccaaagta aggttgcgac aatgagtaaa
    16501 caattggttg caaatgggaa tgaccttgtg gttggtatcg caacaccagc agcccaaggg
    16561 ttggctagtg caacaaaaga cttaccggtt atcatggccg ctattacaga cccaattggt
    16621 gctaacttgg ttaaagattt gaaaaaacca ggtggcaacg ttacaggggt atctgaccac
    16681 aatccagctc aacaacaagt tgaactcatc aaggctctga caccgaatgt gaaaacaatc
    16741 ggagctcttt actcaagtag cgaagacaat tcaaaaacac aggtcgaaga atttaaggct
    16801 tatgctgaaa aagcaggtct gacagtggaa acatttgcag ttccttcaac aaatgaaatt
    16861 gcctcaactg tcactgttat gactagcaag gtagatgcta tttgggttcc aattgataac
    16921 accattgcat caggatttcc aacggttgtc tctagcaatc aaagttctaa gaaaccaatt
    16981 tatcccagtg cgacagctat ggtagaagta ggtggtttgg catcagttgt aattgaccaa
    17041 catgaccttg gtgtggcaac aggtaaaatg attgtgcaag tcttgaaagg tgcaaaacca
    17101 gccgataccc cagtcaatgt cttttcaact ggtaagtcag tcatcaataa aaaaatagca
    17161 caagaactag gtattactat tcctgagtct gttctcaaag aagcaggaca agtcatcgaa
    17221 taaataaggt agggaggagg agactcttcc cattttttaa aaagatgaat atagaaagga
    17281 ttaaataaaa tatgattgtt tccattattt ctcaaggatt tgtctgggct attctaggtc
    17341 tgggaatctt tatgacattt aggattttaa actttccaga tatgacgaca gaaggttcct
    17401 tccctcttgg gggagctgtt gctgtcactt tgataaccaa aggcgtgaac ccatttttag
    17461 cgacacttgt tgctgtagga gcaggttgtt tggctggaat ggcagcaggc cttctttata
    17521 caaaagggaa gatcccaacc ttgctctcag ggattttggt gatgacttct tgtcactcaa
    17581 tcatgctctt gattatggga cgtgcgaatt taggcctgct tggaaccaag caaattcagg
    17641 atgttttgcc ttttgattcg gatttgaatc aactcttgac aggtctcatc tttgtgagta
    17701 ttgttattgc tctcatgctc tttttcttgg acactaaact cggacaagcc tatattgcta
    17761 caggggataa tcctgatatg gctagaagtt tcgggattca tactggacgc atggagctca
    17821 tgggcttggt cttatcaaat ggtgtgattg cccttgcagg tgccctcatt gctcagcaag
    17881 aaggctatgc cgatgtgtct cgagggatcg gggttatcgt tgtggggctt gcaagtttga
    17941 ttattggaga agttattttc aagagtttga gcttggcaga gcgtttggtt actatcgttg
    18001 taggttctat cgcttatcaa tttttagtgt gggcagttat cgcacttggc tttaatacaa
    18061 gttaccttcg tttatacagt gccttgattt tagcagtctg cctcatgatt ccaacattta
    18121 agcaaacaat cttgaaagga gccaagttaa gcaaatgaca gcaattgtag aattaaaaaa
    18181 tgcaaccaaa atcgttaaaa atggctttga tgaagaaaag attattttaa atgatgtttc
    18241 cttagaaatt tttgaacggg actttatcac gattttgggc ggaaatggtg ctggaaaatc
    18301 aactctcttt aacactatag cagggacctt atcactaact agtggaacta tccgtatttt
    18361 aggtgaagat ctcactaagt tttcacccga gaagcgtgcc aagtacctgt ctcgtgtctt
    18421 ccaagatcca aagatgggga cagctccccg tatgacggtc gctgaaaatc ttttaatcgc
    18481 caagtttcgt ggtgaaaagc gtggattgtt accaagacgc ttgactagct ataaggatga
    18541 atttcaggca accattgaaa aagtaggaaa tggtcttgag aaacacttga atacaccgat
    18601 tgagttctta tcaggtggac aaagacaggc tttgagtctc ttgatggcaa ccttgaagcg
    18661 acctgaatta ctcctgttag atgagcatac tgctgccctg gatccaaaga ctagtgttgc
    18721 tttgatggaa ttgacagatg aatttgttaa gaaagatcag ctaacagccc ttatgattac
    18781 tcatcatatg gaagatgctc tcaaatacgg caatcgcttg attgtcatga aagaaggacg
    18841 gattatccaa gatttaaacc aagaagaaaa agcaaaaatg aaaatctctg attattatca
    18901 actctttgaa taaagtaggg aaaatgagtg aaatggttta ctttttttct gaaataaagt
    18961 atactatata aagtaaacta tgataacatg gaggtattgt gtatggttga caaacaagtc
    19021 attgaagaaa tcaaaaacaa tgccaacatt gtggaagtca taggagatgt gatttcttta
    19081 caaaaggcag gacggaacta tctagggctc tgtccttttc atggtgaaaa aacaccttct
    19141 ttcaacgttg tagaggacaa gcagttttac cactgttttg gttgtggtcg ctcaggtgat
    19201 gtctttaaat tcatcgagga gtaccaaggg gttaccttta tggaggctgt ccaaatctta
    19261 ggtcagcgtg tcgggattga ggttgaaaaa ccgctttata gtgaacagaa gccagcctcg
    19321 cctcaccaag ctctttatga tatgcacgaa gatgcggcta aattttacca tgctattctc
    19381 atgacaacga ctatgggcga agaggccaga aattaccttt atcagcgggg tttgacagat
    19441 gaagtgctta aacatttttg gattggttta gcacctccag aacgaaacta tctctatcaa
    19501 cgtttgtctg atcagtatcg tgaagaagat ttactggatt caggcctgtt ttatctctcg
    19561 gatgccaatc aatttgtaga cacctttcac aatcgcatta tgtttcccct gacaaatgac
    19621 caaggaaagg tcattgcctt ctcaggtcgt atctggcaaa aaacagattc acaaacttct
    19681 aagtataaaa acagccgatc gactgcaatt tttaacaaaa gttacgaatt atatcatatg
    19741 gatagggcaa aaaaatcttc tggaaaaact agtgagattt acctgatgga aggattcatg
    19801 gatgttattg cagcctatca ggctggaatc gaaaatgctg tggcgtcgat gggaacggcc
    19861 ttgagtcgag agcatgttga gcatctgaaa aggttaacca agaaattggt tcttgtttac
    19921 gatggagata aggctgggca agccgcgata ttgaaagcat tggatgaaat tggtgatatg
    19981 cctgtgcaaa tcgttagcat gcctgataac ttggatcctg atgagtatct acaaaaaaat
    20041 ggtccagaag acttggccta tctattaacg aaaactcgta ttagtccgat tgagttctac
    20101 attcatcagt acaaacctga aaacagtgaa aatctgcagg ctcagattga gtttattgaa
    20161 aaaatagctc ccttgattgt tcaagaaaag tccatcgctg ctcaaaacag ctatattcat
    20221 attttagctg acagtctggc gtcctttgat tatgcccaga ttgagcagat tgttaatgag
    20281 agtcgtcagg tgcaaaggca gaatcgcatg gaaggaattt ccagaccgac gccaatcacc
    20341 atgcctatca ccaagcagtt atcggctatt atgagggcag aagcccatct actctatcgg
    20401 atgatggaat cccctcttgt tttgaacgat taccgtttgc gagaagactt tgcatttgct
    20461 acacctgaat ttcaggtctt atatgacttg cttggccagt atggaaatct tcctccagaa
    20521 gttttagcag agcagacaga ggaagttgaa agagcttggt accaagtttt agctcaggat
    20581 ttgcctgctg agatatcgcc gcaggaactt agtgaagtag agatgactcg aaacaaggct
    20641 ctcttgaatc aggacaatat gagaatcaaa aagaaggtgc aggaagctag ccatgtagga
    20701 gatacagata cagccctaga agaatttgaa cgtttaattt cccaaaagag aagaatggag
    20761 taataatggc aacaaaacaa aaagaagtaa caacatttga cgtacaggta gcagaattta
    20821 tccgtaatca taagcaaaaa gggacagcaa cagatgatga aatcaatgca agtctggtta
    20881 ttccttttac cttggacgct gatgggattg aagatctctt gcaacggatt caggatgcag
    20941 gcatttctat cacagataac gaaggaaatc caagtgcgcg tgttcttagc aatgaagaag
    21001 aaccagaact cagcgatgag gacttgattg ggtcaacttc tgctaaggtc aatgaccctg
    21061 tccgtatgta cttgaaagaa ataggggtcg ttcctctctt gaccaatgaa gaggagaaag
    21121 agttggcact ggctgttgaa gctggcgata tcgaagccaa acaacgtctt gcggaagcca
    21181 atcttcgttt ggttgtttct attgccaaac gctatgtcgg tcgtggcatg cagttccttg
    21241 acttgattca agaaggaaat atgggcttga tgaaggcggt tgacaagttt gactattcta
    21301 aagggttcaa gttttcaact tatgcaactt ggtggattcg tcaggctatc actcgtgcta
    21361 ttgcggatca agctcgtacc atccgtatcc cagttcacat ggttgaaact atcaataaat
    21421 tggttcgtga acagcggaat ctccttcaag aattggggca agatccgaca ccagaacaga
    21481 ttgctgaacg aatggatatg acacctgata aggttcgtga aatcttgaag attgcccaag
    21541 aaccagtatc tcttgaaact cctatcggtg aagaggacga tagccacctt ggagacttta
    21601 tcgaagatga agtgattgaa aatccagtgg attatacgac tcgtatcgtc ttgcgtgagc
    21661 aattggatga aatcttagat actcttacag accgtgaaga aaatgttctg cgtctacgtt
    21721 ttggactaga tgatggaaaa atgcgcacac ttgaagatgt ggggaaagtc tttaacgtaa
    21781 ctcgtgagcg tatccgtcag attgaagcaa aggctttgag aaaactacgc caaccaagcc
    21841 gcagcaaacc gcttcgtgat tttattgaag actaagagtg aggaaaatat ggcttataca
    21901 gaagagcaaa ttgaaaacat caaaacacgg attttaacag ccttggaaga agtcatcgac
    21961 cctgagttgg gaatcgatat tgtcaatctt ggtttgatct atgagattcg ttttgacggt
    22021 gacacagggc aaacagagat tgacatgact ttgacaacta tgggttgtcc cttagcagac
    22081 cttttgacag accagattta tgatgctatg atagaggttc cagaagtaac ggatactgag
    22141 gttaaattag tctggtatcc agcctggaca gttgaaaaaa tgagtcgcta tgcccgcatt
    22201 gccctaggca ttaagtaaac atataaaagc atgtgagaga ctgttggaaa agcgaggaaa
    22261 tttcccctct tttcctctag tctctccttt cttttgctga ttttattcaa agaaaatgat
    22321 ataatagtag ttatggagaa aaagaaatta cgcatcaata tgttgagttc aagtgagaaa
    22381 gtagcaggac agggagtttc aggtgcttac cgtgaattag ttcgtcttct tcaccgtgct
    22441 gccaaggacc aattgattgt tacagaaaat cttccaatcg aggcagatgt gactcacttt
    22501 catacgattg attttcccta ttatttatca accttccaaa agaaacgctc agggagaaag
    22561 attggctatg tgcatttctt gccagctaca cttgaaggaa gtttgaaaat tccatttttc
    22621 ttaaagggaa ttgtgaaacg ctatgtattt tctttttaca accggatgga gcacttggtt
    22681 gtggtcaatc ctatgtttat tgaggatttg gtagcagctg gtattccacg tgaaaaagtg
    22741 acctatattc ctaactttgt caacaaggaa aaatggcatc ctctaccaca agaagaggta
    22801 gtcagactgc gcacagatct tggtcttagt gacaatcagt ttatcgtagt aggtgctggg
    22861 caagttcaga aacgtaaagg gattgatgac tttatccgtc tggctgagga attgcctcag
    22921 attaccttta tctgggctgg tggcttctct tttggtggta tgacagatgg ttatgaacac
    22981 tataagaaaa ttatggaaaa tccccctaaa aatttgattt ttccaggcat tgtatcgcca
    23041 gagcggatgc gcgaattgta tgctctagcg gatcttttct tgttgcctag ttacaatgag
    23101 ctctttccta tgactatttt agaagctgcg agttgtgagg ctcctattat gttgcgtgat
    23161 ttagatctct ataaggtgat tttggaggga aattatcggg cgacagcggg tagagaagag
    23221 atgaaagagg ctattttgga atatcaagca aatcctgctg tcttaaaaga tctcaaagaa
    23281 aaggctaaga atatttccag agagtattct gaagagcatc tgttacaaat ctggttggac
    23341 ttttatgaga aacaagccgc tttagggaga aagtaaaaag tgaggtaatc tatgcgaatt
    23401 ggtttattta cagataccta ttttcctcag gtttctggtg ttgcgaccag tattcgaacc
    23461 ttgaaaacag aacttgaaaa gcagggacat gctgttttta tctttacgac gacagataag
    23521 gatgtcaatc gctacgaaga ttggcaaatt atccgcattc caagtgttcc tttctttgct
    23581 tttaaggatc gtcgctttgc ctaccgaggt tttagcaagg cacttgaaat tgctaaacag
    23641 tatcagctag atattatcca tactcagaca gaattttctc ttggcctgtt ggggatttgg
    23701 attgcgcgtg aattgaaaat tccagtcatc catacctatc acacccagta tgaagactat
    23761 gtccattata ttgctaaggg gatgttgatc cggccgagta tggtcaagta tctggttaga
    23821 ggtttcctgc atgatgtgga tggggttatt tgccctagtg agattgtccg tgacttgcta
    23881 tctgattata aggtcaaggt tgaaaaacgg atcattccta ctgggattga attagccaag
    23941 tttgagcgtc cggaaatcaa gcaggaaaat ttgaaagaac tgcgtagtaa actagggatt
    24001 caagatggtg aaaagacgtt gcttagtctt tcgagaatct cctatgaaaa aaatattcaa
    24061 gcagttttag cagcctttgc tgatgttctg aaagaggaag acaaggttaa actggtagta
    24121 gctggggatg gcccttatct gaatgacctc aaagagcaag cccagaacct agagattcaa
    24181 gactcagtca tctttacagg gatgattgct cctagtgaga cggctcttta ctataaagcg
    24241 gcggatttct tcatttcggc atcgacaagc gaaacgcaag gtttgaccta cttggaaagc
    24301 ttagccagtg gaacacctgt cattgctcac ggaaatcctt atttgaacaa cctcatcagt
    24361 gataaaatgt ttggaacctt gtactatgga gaacatgatt tggctggtgc tattttggaa
    24421 gccctgattg caacaccaga catgaacgag cataccttat cagagaaatt gtatgagatt
    24481 tcagctgaga actttgggaa acgagtgcat gagttttatc tggatgccat tatttcaaat
    24541 aacttccaga aagatttggc taaagatgat acggtcagtc agcgtatctt taagacagtt
    24601 ttgtatcttc agcaacaggt ggttgctgta cctgtaaaag gatctagacg catgttgaag
    24661 gcttcaaaaa cacagttgat cagtatgaga gactattgga aagaccatga agaatagaaa
    24721 gaggaacagc tatgaaaaaa acaattaatg agaagcggtc gtgataaaaa gattgcgggt
    24781 gtttgtgctg gggtggccca ttatctggat atggatccga ctatcgttca agtcatttgg
    24841 ggtgttctta cttgctgtta cggagctgga attgtagctt acattatttt atggattatc
    24901 gcaccagtag caactgacta ttgaaaacta gctcaattca tgctaagata atagaaaata
    24961 gaatgtaacg aaggagagaa aaatggcatt tggagataat ggaaatcgta aaaaaactat
    25021 gtttgagaaa ataaccttgt ttatcgtgat tatcatgcta gtagcaagtt tattgggaat
    25081 ttttgcaact gcaattggtg ccctcagtaa tctataaaat agattcaaga aaatttagtg
    25141 actgggattt cccagccctt ttttaaagtg agaagaaata atgagtatgt ttttagatac
    25201 agctaagatt aaggtcaagg ctggtaatgg tggcgatggt atggttgcct ttcgtcgtga
    25261 aaaatatgtc cctaatggag gcccttgggg tggtgatggt ggtcgtggag gcaatgtggt
    25321 cttcgttgta gacgaaggac tacgtacctt gatggatttc cgctacagtc gtcatttcaa
    25381 ggctgattct ggtgaaaaag ggatgaccaa agggatgcat ggtcgtggtg ctgaggacct
    25441 tagagttcga gtaccacaag gtacgactgt tcgtgatgcg gagactggca aggttttaac
    25501 agatttgatt gaacatgggc aagaatttat cgttgcccac ggtggtcgtg gtggacgtgg
    25561 aaatattcgt ttcgcgacac caaaaaatcc tgcaccggaa atctctgaaa atggagaacc
    25621 aggtcaggaa cgtgagttac aattggaact aaaaatcttg gcagatgtcg gtttagtagg
    25681 attcccatct gtagggaagt caacactttt aagtgttatt acctcagcta agcctaaaat
    25741 tggtgcctac cactttacca ctattgtacc aaatttaggt atggttcgca cccaatcagg
    25801 tgaatccttt gcagtagccg acttgccagg tttgattgaa ggggctagtc aaggtgttgg
    25861 tttgggaact cagttcctcc gtcacatcga gcgtacacgt gttatccttc acatcattga
    25921 tatgtcagct agcgagggcc gtgatccata tgaggactac ctagctatca ataaagagct
    25981 ggagtcttac aatcttcgcc tcatggagcg tccacagatt attgtagcta ataagatgga
    26041 catgcctgag agtcaggaaa atcttgaaga ctttaagaaa aaattgtctg aaaattatga
    26101 tgaatttgaa gagttaccgg ctatcttccc aatttctgga ttgaccaagc aaggtctggc
    26161 aacactttta gatgctacag ctgaattgtt agacaagaca ccagaatttt tgctctacga
    26221 cgagtccgat atggaagaag aagcttacta tggatttgac gaagaagaaa aagcctttga
    26281 aattagtcgt gatgacgatg cgacatgggt actttctggt gaaaaactca tgaaactctt
    26341 taatatgacc aactttgatc gtgatgaatc tgtcatgaaa tttgcccgtc agcttcgtgg
    26401 tatgggggtt gatgaagccc ttcgtgcgcg tggagctaaa gatggggatt tggtccgcat
    26461 tggtaaattt gagtttgaat ttgtagacta ggagactggt atgggagata aaccgatatc
    26521 tttccgagat gcggatggta attttgtttc cgccgcagac gtttggaatg aaaagaaatt
    26581 ggaagaacta tttaatcgtc tcaatccaaa tcgtgccttg agattggcac gaactaaaaa
    26641 ggaaaatcca tctcagtaaa gaagctaaaa aatcccgtgc ctcatcagac acgggatttt
    26701 gtggtacgac gggcatgtat agcgaactga atctggaata gcacagcata tcttctaaaa
    26761 tatagtaaaa tgaaa
//
LOCUS       DAVLMQ010000022        25939 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000022 DAVLMQ010000000
VERSION     DAVLMQ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25939
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.022"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(273..677)
                     /locus_tag="VXF95_001166"
     CDS             complement(273..677)
                     /locus_tag="VXF95_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000846948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1081720.1"
                     /translation="MKTFLAKKRNIFLARLFLGQLPLLVSTYLFLSRQFLNFSVVFQF
                     LLVVINLASILVTVYLTREMRIREFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITA
                     GESYQQLIAYIGAVLCLIIMLLLMWGLKYYKK"
     gene            complement(674..838)
                     /locus_tag="VXF95_001167"
     CDS             complement(674..838)
                     /locus_tag="VXF95_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081721.1"
                     /translation="MKKKILIIFVLYLIMSIFLYPLRESAWYQLFYTIAYVIAVMIYF
                     AINKKKGEKK"
     gene            complement(1135..1254)
                     /locus_tag="VXF95_001168"
     CDS             complement(1135..1254)
                     /locus_tag="VXF95_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1081722.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDNLIRKIFSKFPKKDTDSTP"
     gene            complement(1257..1487)
                     /gene="blpU"
                     /locus_tag="VXF95_001169"
     CDS             complement(1257..1487)
                     /gene="blpU"
                     /locus_tag="VXF95_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HEV1081723.1"
                     /translation="MNTKMMSQFSVMDNEMLARVEGGGCNWGDFAKAGVGGGAARGLQ
                     LGIKTGTWQGAATGAAGGAILGGVAYAATCWW"
     gene            1768..3815
                     /locus_tag="VXF95_001170"
                     /pseudo
     CDS             1768..3815
                     /locus_tag="VXF95_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
     gene            3826..5187
                     /locus_tag="VXF95_001171"
     CDS             3826..5187
                     /locus_tag="VXF95_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HEV1081724.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVLIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ETQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIVNKRARLPTGNPHQSILNRY
                     LIASQEQTQGTAEEPFLSQINQSIAGLESSIASLKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPIITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     TIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTAKKTYFDYFKDKILT
                     HSD"
     gene            5244..5399
                     /gene="blpC"
                     /locus_tag="VXF95_001172"
     CDS             5244..5399
                     /gene="blpC"
                     /locus_tag="VXF95_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HEV1081725.1"
                     /translation="MDKKQNLTSFQELTTTELNQITGGGLWEDILYSLNIIKHNNTKG
                     LHHPIQL"
     gene            complement(5444..6784)
                     /locus_tag="VXF95_001173"
     CDS             complement(5444..6784)
                     /locus_tag="VXF95_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HEV1081726.1"
                     /translation="MNIVWILLHTLITNGLEIVIFFKVDGINLTFERIFKAFLLKILL
                     VFVFVMISYIVGNVYLSYFMEPLYGIGLSFLLLRGLPKKLLFFYALFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDGYSFTGLCIIIFNFFISLAFLKWLDYDFTSLRREILDTGFQK
                     SLTKINWIMGAYYLVIQSLSYFEYEQGIQSTTVRHLILVFYLLFFMGVIKKLDTYLKD
                     KLHDRLDQEQVLRYRDMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EVYDLVLKDSSKKLQDNKYDLGRLVNVRDRALKSLLAGKFIKAREKDIVFNVEVPEEI
                     QVEGMRLLDFLTIVSILCDNAIEASAEAGQPHVSIAFLKSGAQETFIIENSIKEEGID
                     ISEIFSFGVSSKGEERGVGLYTVMKIVESYPNASLNTTCQDQVFRQVLTMIPTE"
     gene            complement(6798..7535)
                     /locus_tag="VXF95_001174"
     CDS             complement(6798..7535)
                     /locus_tag="VXF95_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081727.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITPSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSPRPHRVILYTKTDRLEFTASLEEVFKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            complement(7540..7878)
                     /locus_tag="VXF95_001175"
     CDS             complement(7540..7878)
                     /locus_tag="VXF95_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081728.1"
                     /translation="MKHMIIQTQKTVYKVNIDDIYYIQTHPTKAHTVQIVTEKASFNM
                     VQNLSNLENQCGETLMRCHRNCLVNLDKLKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            8154..8483
                     /locus_tag="VXF95_001176"
     CDS             8154..8483
                     /locus_tag="VXF95_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1081729.1"
                     /translation="MTDTDPIKRAHTLITDLNKAYQACKQASADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            complement(8651..9700)
                     /locus_tag="VXF95_001177"
     CDS             complement(8651..9700)
                     /locus_tag="VXF95_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081730.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYVISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPLDKGQKEKGLQEVVRGLTSFVLLVELVVGLITFQEKLALLALLGAGLVL
                     QVLYLPYQVKRQMQD"
     gene            complement(9697..10428)
                     /locus_tag="VXF95_001178"
     CDS             complement(9697..10428)
                     /locus_tag="VXF95_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081731.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            10496..10906
                     /locus_tag="VXF95_001179"
     CDS             10496..10906
                     /locus_tag="VXF95_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HEV1081732.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            10916..11203
                     /locus_tag="VXF95_001180"
     CDS             10916..11203
                     /locus_tag="VXF95_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081733.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(11525..12661)
                     /gene="dnaJ"
                     /locus_tag="VXF95_001181"
     CDS             complement(11525..12661)
                     /gene="dnaJ"
                     /locus_tag="VXF95_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HEV1081734.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGDGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGQGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFAAAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(13063..13419)
                     /locus_tag="VXF95_001182"
     CDS             complement(13063..13419)
                     /locus_tag="VXF95_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N7)-methyltransferase"
                     /protein_id="HEV1081735.1"
                     /translation="MSVLDDEYLKNTRKVYNDFCNQADNYEAAKGFIDNIPVECLTIY
                     REIILAEHDSCVKNDEAVRNFVTSVLLSAFVSAMVSAMISLEIQTYKFVIPFIIGMIW
                     TVVVFLMINWNYIGKY"
     gene            complement(13421..15244)
                     /gene="dnaK"
                     /locus_tag="VXF95_001183"
     CDS             complement(13421..15244)
                     /gene="dnaK"
                     /locus_tag="VXF95_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HEV1081736.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(15724..16248)
                     /gene="grpE"
                     /locus_tag="VXF95_001184"
     CDS             complement(15724..16248)
                     /gene="grpE"
                     /locus_tag="VXF95_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HEV1081737.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSKLDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(16275..17309)
                     /gene="hrcA"
                     /locus_tag="VXF95_001185"
     CDS             complement(16275..17309)
                     /gene="hrcA"
                     /locus_tag="VXF95_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HEV1081738.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLEAYQFFDQPQKVALEIREGLREDQMQNVRVADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQVNVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(17473..17910)
                     /locus_tag="VXF95_001186"
     CDS             complement(17473..17910)
                     /locus_tag="VXF95_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001851166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HEV1081739.1"
                     /translation="MHLKGWRYRTSRFGLFYFDQCQPDDVIYRIYDSRFLKKYKHELQ
                     DFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMSKGLKWEVMRSRLRSCTTTFLGGLV
                     VCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFRLKRKYRVDE"
     gene            18590..18890
                     /locus_tag="VXF95_001187"
                     /pseudo
     CDS             18590..18890
                     /locus_tag="VXF95_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            19010..20923
                     /locus_tag="VXF95_001188"
     CDS             19010..20923
                     /locus_tag="VXF95_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1081740.1"
                     /translation="MTKEKGLTYEITEAISTPYYTDAFSMKTPRYYQQIAINRTIETV
                     ARGQKRVMFVMATGTGKTFMAFQIIHRLRKAGLAKRVLFLADRNILVDQTMAEDFRPF
                     EKVMTKITPKLLTAPEKLNSFEIYLGLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAH
                     RGSAKENSNWRKVIDYFSSATQIGMTATPKETKNASNMEYFGEPIYTYSLKQGIEDGF
                     LAPYRVMRVNLDVDVGGYRPETGKVDANGQLIEDRYYGRKDFDKTIVIDDRTQRVAKF
                     VSDYMKQNNARFDKTIVFCVDIDHAERMRAALVKENLDLVQEDYRYVMQVTGDNAEGK
                     AQLDNFMDVNSNFPAIVTTSKLLTTGVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLY
                     PQKGKEFFTIIDFRNVTNLFADPDFDGDPVKVLETGAKTVSGSTPGFVDEEGDPVEKY
                     IVTDKQVTILNSTVQVLDENGKLITESLTDYTRKNILGSYATLNDFITVWHTADKKKL
                     ILDELYKKGVYLDAIRESEGISEQEIDDFDLLLKLAYGQKELTKTERINKLKQSGYLY
                     KYSEEARAVLEILLNKYMDKGIGELESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQ
                     AIKELEQELFTVA"
     gene            20936..22399
                     /locus_tag="VXF95_001189"
     CDS             20936..22399
                     /locus_tag="VXF95_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1081741.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSIM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLNPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            22399..23967
                     /locus_tag="VXF95_001190"
     CDS             22399..23967
                     /locus_tag="VXF95_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1081742.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDDGKHYGKFADGSTQEIDVPYDIPDTWEWVRFSTLVEIVRG
                     GSPRPIKDYLTSEVDGINWIKIGDTEKGEKYINNVKEKIKKSGLNKTRFVKKGTFLLT
                     NSMSFGRPYILNVDGAIHDGWLAISNYENSLNKDYLFYILSSNVVYSQFLSLISGAVV
                     KNLNSDKVASILIPLPPLSEQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKK
                     SILQYAMQGKLVEQDPNDESVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQGDDNS
                     YYEEVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCNQWSGFSIDLAR
                     FIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWAVADSHVTVIRV
                     LSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIPLPPLPEQSRIV
                     DKIEQFFAHIDALI"
     gene            24024..24821
                     /gene="psrA"
                     /locus_tag="VXF95_001191"
     CDS             24024..24821
                     /gene="psrA"
                     /locus_tag="VXF95_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HEV1081743.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            24832..25440
                     /locus_tag="VXF95_001192"
     CDS             24832..25440
                     /locus_tag="VXF95_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001859489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1081744.1"
                     /translation="MVKLTTCYFCDYGSYYGNKDETSSYPIYEIPEAWRYIKFASLVN
                     FRIGKTPPRSEATFWGTEIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTL
                     LMSFKLSIGKVAILDIPATHNEAIISIFPYANKENIIRDYLMIFLPLISTLGDSKDAI
                     KGKTLNSTSISELLIPISNHEEMKRIISKVDLLFQKVSQLFE"
     gene            complement(25388..25933)
                     /locus_tag="VXF95_001193"
     CDS             complement(25388..25933)
                     /locus_tag="VXF95_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001104691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1081745.1"
                     /translation="MNWVVIKIKDIFSMNTGLSYKKGDLSINNKGVRIIRGGNIKPLE
                     FSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHIGKFARIDKDYDGVVAGGFIF
                     QLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQALYNIPKTTLSELLIPLAPFE
                     EQELITQKVEKLFEKVNQLWK"
BASE COUNT         8429 a         5079 c         4673 g         7758 t
ORIGIN      
        1 aaaagtggta cgctgaacac caacaagacg cttaaatcgt gcatcagtta gttgtttact
       61 tgcttcataa ttcatagaac tatagtaaaa tgaaataaga acaggataaa tcgatcagga
      121 cagtcaaatc gatttctaac aatgttttag aagtagaggc gtactattct agtttcaata
      181 tactatacca tattttgttt cgcagggaat ctattataaa agggtaagta ttgcaaaaac
      241 acttaccctt ttcttttata cttcattaag ctctactttt tataatactt caagccccac
      301 atgagcagaa gcatgatgat taagcagaga acagcgccaa tataagcgat tagttgttga
      361 taagattctc ctgctgtgat acctctatac aaacaaataa tagacataaa acctgtcaag
      421 ccgataaaca taagttgatt ggttctagga ctaaccaaat catcatcttc aaactctctt
      481 atcctcattt ccctagtgag ataaacagta accaaaatag aagccaagtt aataactact
      541 aaaagaaatt ggaaaactac ggaaaaattt aaaaactgac gagatagaaa tagataagta
      601 gaaacaagca agggcaactg acctaagaac aatctcgcaa ggaagatgtt ccgtttttta
      661 gcaagaaaag ttttcatttc ttttctcctt tctttttatt gatagcaaaa tagatcataa
      721 ctgcaatcac ataggctatg gtataaaata gctgatacca agcactctcc ctaagcggat
      781 atagaaagat ggacatgatt agatacagaa cgaaaataat cagtattttt ttcttcataa
      841 gatttcctcc taaatgtgcg atttatctta gttgagcaag aacatttaca ctgctagtat
      901 agcacttatt ttgaccttgg atcactcaaa tcataaatgg tcatcaaaac ctcttgaatt
      961 gtaaaaatta aaaaagcaag catgaaaaac atactttcct ctttatattg tattgatacc
     1021 aacttgtttg tagacttttc atcctgctat cacatatcat tttgacaggc gaaacaaaat
     1081 taaagaaact cccctgtaaa ttaagctagc aaatacaggg gagaaattta ttttttaggg
     1141 ggtactatct gtatcctttt tgggaaattt tgaaaatatt tttctaatta aattatccat
     1201 ataaggacca aatataccaa ctactaaacc aataataaaa cttttaaaat ccataattac
     1261 caccaacatg ttgctgcata ggctacacct ccaagtatag ctccacccgc agcaccagtt
     1321 gctgcacctt gccatgttcc tgttttaatg cctagttgaa gacctcttgc tgctcctcct
     1381 ccaacacctg ctttggcaaa atctccccaa ttgcatccgc caccttcaac acgagcaagc
     1441 atttcattat ccataacaga aaattgtgac atcatttttg tattcatgac aaatactcct
     1501 tttttatttt taatttttgt cttgttgcaa ctttgacaag tttagtatat catcgttttt
     1561 taaaattttt catccagatc ttgaatagtc atcgaaacgt cttgaattag cttttcattt
     1621 gaaaccacct ctaaattttt taaaaaaaga taatttctaa ttatttttta ccattcagga
     1681 agtttcaatg actattcaag atttaataaa atatgaactt atttttatgg cataatatac
     1741 ctatctacta tatgaaagga attgccaatg acttcttata aacgtacatt tgttcctcaa
     1801 atagatgcga gagactgcgg tgttgctgcc ttagcctcga ttgctaaatt ctatggttca
     1861 gatttttctc tagctcactt gagagaactt gcaaagacca ataaagaagg gacgactgct
     1921 cttggcattg taaaagccgc tgatgaaatg ggctttgaaa caagacctgt tcaagcagat
     1981 aaaacgctct ttgacatgag tgatgtcccc tatccattta tcgttcacgt taacaaagaa
     2041 ggaaaactcc aacattacta tgttgtctat caaacaaaga aagactatct gattattggt
     2101 gatcctgacc cttctataaa aatcactaaa atgtcaaaag aacgcttttt ctctgaatgg
     2161 actggagtag ctatttttct agctcccaaa cccagctatc aaccccataa agataaaaag
     2221 aatggtctac taagcttcct tcctctgatt ttcaaacaaa aatctctcat tgcttacatt
     2281 gttctctcaa gcttattggt cactattatc aatatcggtg gttcttatta tctccaagga
     2341 atcttagatg aatacatccc aaatcagatg aaatcaactt taggaatcat ctcagttggt
     2401 ctggttatca cctatatcct ccaacaagtc atgagcttct ccagaaatta agcattgatg
     2461 tgattttatc ctatattcgc catatttttg aacttcccat gtctttcttt gcgacacgtc
     2521 gtacaggaga aatcatttca cggttcacag atgctaactc tattatagat gccttggctt
     2581 ctacccttct ttctcttatt tccattccta tatacatgtt catcatcttt tcttttatga
     2641 aacctttcga aaaaatgaac catgatgtca tgcaaagtaa ttctatggtt agctctgcca
     2701 ttatcaaaga tatcaacggg attgaaacta taaagtcgct cacgagtgaa gaaaatcgct
     2761 atcaaaatat agacagcgaa tttgtagatt atttggaaaa atcctttaag ctcagtaaat
     2821 attctatttt acaaacgagt ttaaagcagg gaacaaaatt agttctgaat atccttatcc
     2881 tatggtttgg cgctcaatta gtcatgtcaa gtaaaatttc tatcggtcag ctgattacct
     2941 ttaacacact tttttcttac tttacaactc ctatggaaaa tattatcaac ctccaaacca
     3001 aactccaatc tgcgaagatc gctaataacc gtttgaacga agtctatcta gtcgaatctg
     3061 aatttcaagt tcaagaaaac cctgttcatt cacatttttt gatgggcgat attgaatttg
     3121 atgacctttc ttataagtat ggttttggac gagatacctt aacagatatt aatctcacga
     3181 ttaaacaagg agataaggtt agcctagttg gagttagtgg ttctggtaaa acaactttag
     3241 ccaaaatgat tgtcaatttc tttgaaccct acaaagggca tatttccatc aatcatcagg
     3301 atattaaaaa cattgataaa aaagtcttgc gccgtcatat taattaccta ccccaacaag
     3361 cctatatctt taatggctct attttggaaa acttaacctt gggcggtaat catatgatta
     3421 gtcaagaaga tattctaaaa gcttgtgaag tagctgaaat ccgtcaagac attgaaagaa
     3481 tgcctatggg ctatcaaact cagctctctg atggagctgg tctatcagga ggacagaagc
     3541 aacgaatcgc cctcgctcgt gctcttttaa ctaaatctcc tgttttaata ctagatgaag
     3601 ctactagcgg tcttgatgtc ttgactgaga aaaaggttat agataatctt atgtccctaa
     3661 ctgataaaac cattctcttt gtagcccatc gtctcagtat agccgaacga actaaccgtg
     3721 tcattgttct tgaccagggg aaaatcattg aagttggtag tcaccaagag ttaatgcagg
     3781 cgcaaggctt ctaccatcat ctattcaata aataaggaga atgtcatgaa tcctaatctt
     3841 tttagaagcg tcgagtttta tcagagacgt taccataact atgcgacagt gttaattata
     3901 cctctttcat tactgtttac tttcatcttg attttctccc ttgttgccac aaaagaaatt
     3961 actgttactt cccaaggaga aatcgcccct acaagtgtca ttgcatctat tcagtcgacc
     4021 agtgataatc ctatccttgc taatcattta gtggcaaatc aagtagttga gaaaggtgac
     4081 ttactcatca aatactctga aacaatggaa gagagtcaga aaactgcctt agaaactcaa
     4141 ttacaaaggc ttgagaagca aaaagaagga cttggaatct tgaaacaaag cttagaaaaa
     4201 gcgactgatc ttttttctag cgaggatgag tttggctacc ataatacctt tatgaatttt
     4261 actaaacaat cccatgatat tgaactgggt atctcaaaga ctaacactga agtttcaaat
     4321 caagctaatc ttaccaatag cagttcatca gccatcgaac aagaaattac aaaagttcaa
     4381 caacaaattg gagaatatca agagctgaga gatgctatcg taaataaaag agctcgctta
     4441 ccaactggca atccgcacca gtcaatttta aatcgttatc ttatagcctc tcaagaacaa
     4501 acacaaggaa cggcagagga gccattttta tctcaaatta atcaaagtat tgcaggtctg
     4561 gaatcatcta tcgcaagcct caaaattcag caagctggca tcggaagtgt agcaacttat
     4621 gataatagtt tagcaaccaa aattgaagta ctccgcactc agtttttaca aacagcctct
     4681 cagcaacaac taaccgtgga gaatcaatta acagaattaa aagtacaact agatcaagcg
     4741 acacagcgct tagaaaacaa taccttaacc gctccaagta aaggtatcgt tcatctgaac
     4801 agcgaatttg aaggtaaaaa tagaattcca actggtacag aaattgctca aatattccct
     4861 atcatcacag atacaagaga agtactaatc acttactacg tatcttctga ctatctacct
     4921 ctactagata aaggacaaac tgtaagatta aaactggaga agattggaaa tcacggcacc
     4981 accatcatcg gccaacttca gacaattgat caaactccta ccagaacaga gcaaggtaat
     5041 ctctttaaat taaccgctct tgcaaaacta tctaatgagg atagtaaact catccaatat
     5101 ggcttacaag gtcgcgtcac tagtgtaact gcaaagaaaa catattttga ttatttcaaa
     5161 gataaaattt taacccattc tgattaattt tcagataaca ctctataact atttattatc
     5221 ttatcaaaaa ggagaatcat aacatggata agaaacaaaa cctaacttca tttcaagaac
     5281 taacaactac cgaactcaac caaattacag gtggaggact gtgggaagat atcttataca
     5341 gccttaatat aattaagcat aacaatacga aaggacttca tcatccaata caactataaa
     5401 aaataagacc gagtaacaag aactctcggt cttatttttt tcatcattct gtaggtatca
     5461 tagtaagcac ctgacgaaag acttgatctt gacaggtagt atttaaactg gcattgggat
     5521 aactttccac aatcttcata acggtataga gaccgacacc tctctcctcc cctttagaac
     5581 taactccaaa ggagaagatt tcagaaatat cgatgccctc ttctttgatg gaattttcga
     5641 tgatgaaggt ctcctgtgct ccacttttta aaaaggcaat tgaaacatga ggttgaccgg
     5701 cctctgcact cgcttcaata gcattatcac aaaggataga cacaatggtt agaaaatcaa
     5761 gcagtctcat cccctcaacc tgaatctctt caggaacttc gacattaaag acaatgtcct
     5821 tttctctagc ttttataaat tttccagcta ggagactttt gagggcacga tcccgaacat
     5881 tcaccaatcg gcccaggtca tatttattgt cctgcaattt tttactagaa tcctttaaga
     5941 ccaagtcata gacctctttt atctgctcca tatcctcctc ttcaataccc agacgtaaac
     6001 ttgtcaagag gttggtgtag tcatggcgaa aactccttac ttccttgtaa agttcctcta
     6061 tatgccgact atagcgttcc atatctctat agcgcaagac ctgctcttgg tccagtctat
     6121 catggagttt gtccttcaaa taggtatcca atttcttgat aacccccata aaaaatagga
     6181 ggtagaacac taggatgaga tggcgaacag tcgttgattg aataccttgc tcatattcaa
     6241 agtaagacag actttgtatc accaaatagt aagcccccat tatccagtta atcttagtca
     6301 gggacttttg aaaacctgta tctagaatct cccttctcaa actagtaaaa tcatagtcca
     6361 accatttcaa aaaggctaga gaaatgaaga aattgaaaat tattatacat aacccagtaa
     6421 atgagtagcc atcatatact tgcccttgtc ccaaaaatgg aagcacaaaa taggagactc
     6481 ctctataaaa gagattcacc aatatcattg gaaagagagc ataaaagaaa aggagttttt
     6541 taggaagccc tcttaacaat aagaaagaca agcctatgcc gtacaagggt tccataaaat
     6601 aagataggta aacatttcct actatatagc taatcattac aaaaacaaag accaacagta
     6661 tcttcaaaag aaaggcctta aaaatcctct cgaaagtaag attaattcca tccaccttaa
     6721 agaaaatgac aatttctagc ccattagtaa taagtgtatg caataatatc caaacaatat
     6781 tcataaactc tcctagttca gtgtaagtta ttaatagcct cagacacttc cctgacctta
     6841 taacgggcga ttagacaact tcctccattg ggaaagaaaa gcagtttttc tttcttatcc
     6901 aaatgcacca catttgcagg attgatgaga aaggagcgat ggcactgcaa aagacgaggt
     6961 tcctgcttaa aaacctcctc taaactcgct gtaaattcca gcctgtctgt cttggtatag
     7021 agaataacac gatggggtct tggggatgtt tcgagatagt aaacctcttt aaaaggatac
     7081 tggaattggg caaattttga tttaaagtaa aagcaatctt ccgccagact tttactatct
     7141 tgactattgg catagaggag ggctgtctcg attcgagatt caaactcctc tgccgaaagg
     7201 gccttatcaa tatagtccag agcagacact tggtagcgaa aggacagggg cataaactcc
     7261 gagtgagtcg tcacaaagac aatcagggca taggggtctc gatcccgaat ctttctagcc
     7321 acttccagcc ccttcatctc ctcatttcga atctcaatat ccaaaaagaa tagctgatgg
     7381 gcccccttct catgcacctc tgccagcagt tggtctggct tgccaaatac ctcaaaagag
     7441 ctgggagtga tatgatgttc cttcaagagt ttctcaatcg tcgtttcaat cctagtctgt
     7501 tgggaaaaat catcctctaa aacaaatatt ctcatcttct tactctccct ctttcaacca
     7561 tttttgacga atttctctat agcgacgtct ggcatacttg acagcgtatt gaccttcttc
     7621 tccgagaaaa aggattcttt cttgaaaatc aatcgatttt aatttatcaa gattaactaa
     7681 acaatttcga tgacatctca tcaaggtttc cccacattgg ttctcaagat tacttaaatt
     7741 ttgaaccata ttaaaactag ctttttctgt aacaatctgt acggtatggg ctttagttgg
     7801 atgtgtttgg atatagtaga tatcgtcgat gtttacttta tagactgttt tctgtgtctg
     7861 aataatcata tgtttcattg gattctcctc ctaagaaaag aataacagaa aaggtctagc
     7921 ccaagcccac ccaatcctaa acagtctttg aaaactccta aaaggattat tttctacaac
     7981 atcatgatga gcttacaact attttatcat aaaattcact cagcgcaatt caagacattt
     8041 caatgacaat taaagatttg aataaaaaaa aagaattaaa agtgataaac taacagtatc
     8101 aaaacacagt tgccagaagt aagactggca cccagattaa aggaggcatt cccatgacag
     8161 atacagaccc catcaaaaga gctcatactt tgattactga cttaaacaaa gcctaccaag
     8221 catgcaaaca ggcaagcgct gacgacgtcc gctttcagga gcaattaaac tctattcttg
     8281 gttttctagc caaggctgaa acagtggata atcgattctt gattgaattg gaaaaatttt
     8341 accagacttc cagtcttctc atgggactca gcgctcttga tccagatgct ccaactcgcg
     8401 ccgcttggcg ggcctatgac cgcttccact ttgaccaagt caagaccaag ttaatactca
     8461 atgaaaatca aagagcaaac taggaagcta gccgcaagct gtacttgagt acggtaagac
     8521 gacgctgacg tggtttgaag agattttcga agagtataag tctctacgga ccaaccatta
     8581 tcctgtagta acaaaaaaga agctgagaca gactgaactc aacttctttt ttagtgtcgt
     8641 atcagcaatg ttagtcctgc atctgacgtt ttacctgata aggcaaatac aagacttgta
     8701 aaaccaaacc agctcccagt aaggctagaa gggctagttt ttcttgaaag gtaatcaacc
     8761 caacaactaa ttccacaagt aaaacaaaac tggtcaatcc tcgaactacc tcctgtaagc
     8821 ctttttcctt ttgccccttg tccagcggaa agagttgggt caaatactgg tagtcaaagg
     8881 catgatagag ggccagcaac tggaagagca agaggtagtt aaagagaact accactgctg
     8941 tcgcaatcca agcttgctcg ataaaaacct gcgccagtac ggaaagtaag agaagacgaa
     9001 gactgagagc aaagaggtcg ccatttcgca gataagaacg cagatagaga ttttgccaaa
     9061 tcttcccagg caccttctga acagccttta agataaagtc cagataggca cgacgcttaa
     9121 cgctgtttga aattcccttg acctgcgtaa agagggcaaa gaaacgaagc aagacttgct
     9181 tacgcttgct ttcttgagaa ataacatagt cccagtccag tccagtttca gtgaaaaatt
     9241 tgctggcctt ttgacgaaag tggaaatatt ttcctacccc caataaaagc acatagagca
     9301 gaaaaactgg caagccataa cccattgcta aaaataaagg cgcaaataac agcaagaaaa
     9361 gggtctgtac aaagagccaa aagactaggg aaatgccagt ttgacgcttg agatggagct
     9421 tgatttcctc ttctccaact aagagaaaga gcttgtctgg agcctccata taggtggcaa
     9481 ttcctcccca aagtaaaagt aaaacagacg taattcctac aaacaaaagg ataggccaat
     9541 gattttcagg aaaatgttgt aagagttgac tgtactggta ggctagaaag cccaacagga
     9601 caagcaggaa caagacaaag tggtcattga gcacatagcg cagataacca agacactcct
     9661 tacgaaaggc ctgctttctc tttaaaaaca agtctttcat aggtcctcct cttttgtcag
     9721 agccaagtaa atatcattca aactagcctc aggcatatca aaggcttcgc gtagttgcag
     9781 gagattgcct ttggcacgca cctctccctt gtgaagaatg acaaaggcat cacacatctt
     9841 ctccgccgaa tccagcacgt gggtactcat gagaatagac ttgccctttt gcttctccac
     9901 ttccaaaagc tgaatcaaat cagaaatagc tagcggatca agaccaagga aaggctcatc
     9961 cacgatgaaa agacttggat ccaccacaaa agcacagata atcatgacct tctgcttcat
    10021 cccttttgaa aaatgaacag ggaaccagtc taatttctgg tccagacgga acatctttaa
    10081 caagggctct actcgttcga aagccacttt ttgctcaata ccgtaagcca tagcaaccgt
    10141 ttcgatatgc tctctgaggg tcaattcctc atacagacta ggcgtctcag gaatgtagcc
    10201 aatctgcttg cggtagctag tcgcatctcc ttgcagagtc aggccattga tattgatgga
    10261 gccactataa ggtgccaaca gaccgataat ctcattgatc gtcgttgatt tcccagcacc
    10321 attgagacca atcaaaccga ccaactgccc actttcaaca gtaaaggaca catctttcaa
    10381 aacaggaaca tgaacatagc cacctgtcag gtttttaatt tctaacatat tttctccaaa
    10441 tctggtataa tgtagctata ttatatcaaa attcagtaca gtagaggtag attttatgtc
    10501 agattgcatt ttttgtaaaa tcatcgcagg ggaaattcct gcttcaaaag tatatgaaga
    10561 tgagcaggtc cttgcctttc ttgatatctc tcaagtaaca ctaggacaca ccttggtcgt
    10621 gccaaaagaa cactatcgca atcttttgga gatggatgct acgagcgcca gccaactctt
    10681 tgcccaagta ccaaaagtag ctcaaaaagt catgaaagtc actaaggctg ctggtatgaa
    10741 tatcatttcc aactgtgaag aagtcgctgg tcaaacagtt tttcatactc acgttcacct
    10801 tgtgcctcgc tacagtgctg acgatgacct caagattgat tttatcgccc acgaaccaga
    10861 ctttgacaaa cttgctcaag tcgctgaaac catcaaaaac gcttaaggag ttgctatgaa
    10921 attatccaac ctactgctat ttgcaggagc tgcagccgga agttatctgg ttacaaaaaa
    10981 tcgccaaacc atcacagatg aagtcttgaa taccactgac cgcgttcaag ctatcaagga
    11041 cgatgtggat attatccaaa acagcctgca aatcattaac cagcaaaaag aacttatcaa
    11101 ggaataccaa gaagacttga cttacaagtt taaggtcttg gaaaaggata tccagactag
    11161 actagctgtg ataaaagaaa tgcagggaac tgaagataag taaaaagagc cccccggctc
    11221 ttttttaaaa cgtaaacaag ttatagtgaa ttgaatttag aatagcacac catagtttct
    11281 aaaacattgt tagagattac tttaaaatcc tcttatcaat ttgttcatat tctatttcaa
    11341 tctattatat atatcccatc aactatgcat cataatttag gtaactcata ctcaatgaaa
    11401 atcaaaaagc aaactaggaa actagccacg ggctgctcaa aacactgttt tgaggttgta
    11461 gatacgactc acatatatac ggcaagccga cgctgacgtg gtttgaagag attttcaaag
    11521 agtattattc tccatcaaag gcatctttaa tatgatcaaa gaagcctttt ttctttggat
    11581 ttactttcaa gtcaccagca gccgcgaatt ctttcaaggc tactttttgg cggtcgttca
    11641 agcctgtcgg tgttacgaca ttaacagtaa cgtattggtc accaactgca ccgccacgaa
    11701 ggctcggtgc ccccttacta cgtaggcgga atttcttacc agtctgagtt ccctctggaa
    11761 taaccaattc aacatcaccg tgaacagttg gaatatctac tgtatcacca agagccgctt
    11821 ggacaaagtt gaggttgaga ttgtagaaga tagtcgttcc ttcacgttca aacttgtcgc
    11881 tagcttccac agaaactact acatacaagt caccataagg tccaccgtta aagcctgctt
    11941 caccttgacc agcgaggcga atttgttgac ctgtttccac accagcaggg attttcacat
    12001 gtacgctatg agcttgtttc tcatgacctg ttccatgaca ggttgtacat ggatatttga
    12061 tttcttttcc ttggccgtga cagacatcac aggttacttg gcgacgcatc ataccaagag
    12121 gagtctgcgt atcgacgtta atgacaccag cgccatgaca gcgtccacaa gtgactggac
    12181 ttgtccctgg cttagcacca gagccattac atgtacgaca gccagcttca cgatgatact
    12241 taacttcctt ctcagttccg aagatagctt cttcaaaggt caaattgaca cgatactgga
    12301 gatcatctcc ttggcgagga gcgtttggat tgcgcgaaga accgcctccg ccgaagaaac
    12361 ttgagaaaat atcctcaaaa ccaccgaagc cacctgcccc attgaaaccg ccgaaaccac
    12421 catctccacc aaaaccacca ttggcgcctg cagcaccata ctggtcatag gcagcacgtt
    12481 tttggtcgtc actcaaagtc tcataggctt cttgaacttc cttgtacttg tcctcagcac
    12541 caggctcctt gttgatatct gggtgatatt ttttggaaag cttacgataa gcctttttga
    12601 tttcgtctgc cgaagcgttt ttggataccc ccagacgatc ataaaattca gtattgttca
    12661 taattcaaga tacaaagggc gtcaaacgga cacagccatc taggagtttt gacgacggac
    12721 gcttatgtcc tagaaaaaac tatctttttg gcacagtccg tagcccgtgt tcagttacga
    12781 acacccttat tcctttctat tgatgttctg aatcgaacca ccatttaggt cggattcaat
    12841 tcctttcttt tatatttagt aagaaattct gaaacccgtg ttcagttacg aacactcttt
    12901 gttcctttct attgatgaga caaaacccaa acaaatgaga ttccgtccct ttttatcgaa
    12961 aaacagaggc tgggttgcaa cctctgcaaa taagtaaatt aactttattt tgattttaaa
    13021 tatcctataa gtacagaaat atttatatat ttttgtctct tcttagtatt tgcctatata
    13081 attccaattg atcataagaa atacaactac tgtccaaatc ataccaatta tgaacggtat
    13141 tacaaattta tatgtttgta tttctaatga tatcatagct gataccatcg ccgatacaaa
    13201 tgcagacaac aatactgaag taacaaaatt ccttaccgct tcatcatttt tgacacaact
    13261 atcatgctca gctaatataa tttctctata tatagtcaaa cattctactg gaatattatc
    13321 tataaaacct tttgctgctt catagttgtc agcttgatta caaaaatcat tataaacttt
    13381 tcgtgtattt tttagatact catcatccaa tacactcatc ttatttttcc gtaaactctc
    13441 cgtctacgac gtcatcgcct gcgtttcctg ttgcttgtgc gccttctgct ccttcttgag
    13501 cttgttgcgc tgctgcggct tgttcgtaga gtttcacagc aaggccttga gctttttcgt
    13561 tcaacgcttc aagtttcgct ttcatgtcgt ccaagttgtt gtcttcttga gctttcttaa
    13621 ggtcatcaag ggcagcttgg gcagcgtcac gttctgcgtc gaagccttta ccttcagttt
    13681 ccttgattgt cttttcagtc gcaaagattg cttggtctac ttcattacga aggtctactt
    13741 cttctttacg tttcttatca gcttcagcgt ttgcttctgc atctttcatc atgcggtcga
    13801 tttcttcgtc agtcaaacct gagttcgatt ggatgacaat agtttgttct ttttgagttc
    13861 caaggtcttt ggccttaaca gacacgatac cgttcttgtc gatgtcaaat gttacttcga
    13921 tttgaggaat tccacgaggt gcagctggga tatcagtcaa ttggaagcgt ccaagagtct
    13981 tgttatctgc tgccattggg cgttcacctt gaagaacgtg gatatcaacg gctggttggt
    14041 tgtctgctgc tgttgagaag acttgtgatt tagatgttgg gattgtagtg ttgcgatcga
    14101 taagttttgt aaatactcca cccattgttt cgataccaag tgacaatggc gttacatcaa
    14161 gaaggacaac gtccttgaca tcaccagtaa tcacaccacc ttggatagcc gcacccatag
    14221 caactacttc atcagggttt actgatttgt ttggttcttt accagtttca gctttaacag
    14281 cttcaacaac ggcagggata cgagttgaac caccaacaag gataacttcg tcgatttctg
    14341 acaagctcaa acctgcatct gaaagggctt gacgaactgg aacttttgta cgttcaacaa
    14401 ggtcacgagt caaatcgtca aatttcgcac gagtcaaagt catttccaag tgaagaggtc
    14461 cagcttcacc tgcagtgata aatggcaagc tgatttgtgt tgaagttaca ccagaaaggt
    14521 ctttcttcgc tttttcagcc gcatctttca aacgttgcat tgccatcttg tcagtagaca
    14581 agtcgatacc gttttctttc ttgaattctg ctaccaagtg gtcaatgatt ttttggtcaa
    14641 agtcgtcacc accaagtttg ttgtcccctg cagttgacaa tacgtcgaag acaccgtcac
    14701 ccaattcaag gatagagacg tcgaatgtac caccaccaag gtcaaatacc aagatttttt
    14761 cttctttgtc agtcttgtcc aaaccataag caagagctgc tgcagttggt tcgttaacaa
    14821 tacgttctac ttcaagacca gcaattttac cagcgtcttt tgttgcttga cgttgagcgt
    14881 cgttgaagta agccggaact gtgataacag ctttggttac tttctcacca aggtagtctt
    14941 cagcgtagcc tttcaagtat tgaaggatca tagctgagat ttcttgtgga gtgtattctt
    15001 ttccatttgc agaaactttt tcagaagttc ccatcttaga tttgatagag ataactgtat
    15061 ctgggtttgt gactgcttga cgttttgcag catcaccaac gatgatttct ccgtttttga
    15121 atgagactac agatggagtt gtgcggtttc cttctgggtt tgcgatgatt ttgctttcag
    15181 ttccttcaag aactgcaact gctgagtttg ttgtacctaa gtcaataccg ataattttag
    15241 acatgtgttt ttctccttgt tagttaattt tctatttttc tttttgatac tcttcttaag
    15301 tggcgacgcc gtcagagctt gacttcgtca gtctctttga ctaaactttg agcctaaggt
    15361 ctcaaaattt gcgcaaatag cgccacggcg aagagtatcg tctttggttc gcttcgctca
    15421 ctattacaaa gcaaaacata ttttatcttt cttcatagtt tattgtcgtt tcggacaagt
    15481 tttctattat gtaaattgcg acacgaggag tcgaaatcga ttttatttcg acgacgagtt
    15541 agtaaggaag ctaggcaaac gccatagcaa ttgccgtttt ctgacgagtt gctttagcta
    15601 ccgtcagaat tgccgaatcg aacacgccct aagctctgag taaaaaagat agattttctt
    15661 gtgttcatcg aacacttcgt caatctccta tttttactgc gagcttttta cgagctttgt
    15721 atcttagtta tacaccacta ccattgctgg gcgtaggatg cggtcatgga gtttgtagcc
    15781 tttttgaaag acttgggcga tggtatctac tgggtgttca tcgtctgctg ggagagtttg
    15841 gatggccata tggtagttat ggtcaaattc gccatctgct gcgatttctt caattccttc
    15901 ttctttcaaa gcgtgaatca agctttcttg caccatcccc aagcccttct tcacatcatc
    15961 tgtcaaacct tcaactgcaa gtgcacgctc aaggttgtca agagatggta agattgcttt
    16021 tgccaagtcc tggctacgat aacgttgcaa gttttgacgt tcttcattgg cacggcgttg
    16081 gatattttgc atttctgcat gagcgcgaag atatttgttt tcgaactcat ctgcacgttc
    16141 atttgccaag tccaacttag acttttcagg agttgtttct tcagctgttt ccacaacttc
    16201 ctcttcttga acttcttcta cttcttcatt ttttatatct tgggccatgt tcgcctcctt
    16261 taatgatttc aatcttaatg tacttcgtaa tgattactgc tgaggtagcg gtaaaaatct
    16321 gtcaacttca tagtcaaaac acggttgacc acattgactt gattgattag ctgttggtaa
    16381 tccagattaa ctggaccgat aatggctaga attccaactc ctcgataagg aatgaggaac
    16441 ttactactaa tcaccgctag gtcagctaaa caggactctt gaccgtctgc aacacgaaca
    16501 ttttgcatct gatcctcacg caacccctca cgaatctcca aggccacctt ttgcggttgg
    16561 tcaaagaact gataggcttc tagattggca aaattcaaga gattgacctt gcccgccatc
    16621 acaatgtttt cgttgaacat ttccttaaag atgtgttcaa agagatcgat gacattatcc
    16681 gttgttgtaa agtaacgctg gataatctgc ggaatctccg tccgaatctt gtagtgaata
    16741 tctaaaacgg tgtgaccgag gaaacgttcc tgaatgatgc tcttcagttt cagcaaatcc
    16801 tcctgcaaga agttccttgg aatcagaaac tgactagtaa ccgttcgcga ctcgtctagg
    16861 gtaaataccg ccaaggctgt atgttgcccc aaaacaacga tatcaaaggc tgtcaaacgt
    16921 tgcctgctcg gctcaacatc cagtgccact accgtacagc cactcaggtc tgttagcaag
    16981 ttagcagcct cttgcagaat atcctccaat ttgaagaatt cctgatcaaa ggctttgaca
    17041 atctcatata cctcattttc agccagccgg tgaaaatcca gtgagtgttt cacatagtac
    17101 tgaaaaccag caacacttgg catccgaccg cttgaagtat gagccttctc aagcaaccct
    17161 tgtttttcta gttccgccat gtcattacga atggttgcac tgctagagtt aatagactct
    17221 tgcaaggctt ttgatccgac aggttcgtgc gttttggtaa agatgtcaat aatcagattt
    17281 aaaatatcct gctgacgctc tgtaaccatc tcatcactcc tctctgtctg atcaattagc
    17341 actcaatgca tccaagtgct aacttatgat tctattatac acccttaaaa gagaatgtca
    17401 agacaaaaac tcaaaaaatt agcactcttt tatcaagagt gctaaaaatc aatctgaaga
    17461 cctagaacct tgctattcat ctactcggta tttccttttt agtctgaaat aaccatgaat
    17521 tagataagaa atcagaaaag catataaaac aaaaataaga aagaaagaca tagaaagatc
    17581 ctctctaaac aaactcgtac aaacaacaag accacctaag aaagtagttg tacaggaacg
    17641 aagtctagat cgcataactt cccatttgag ccccttactc atatagactt gatcctctgg
    17701 aagtaaatca gaagacgatt tacgaagaat cgaacaagaa cctgctccta tcaattccca
    17761 acctctatct ctaaaatctt gcagttcatg cttatatttt ttaagaaatc tagaatcata
    17821 gatacggtag atgacatcgt ctggttgaca ttggtcaaaa tagaacaaac caaaacgact
    17881 cgttctatac ctccaacctt tcaaatgcat ctcatgtaaa tattcttctt acttgtccaa
    17941 atcaacaatg gtgaaaatcc gaaattctac tctgctattc attgtcttac cccaaaatta
    18001 gaaaacatgc ctggcgttat ttattagata attctttcca cttttgactc aatctccaaa
    18061 aaatataaga aatctgaatc gcaaaaacta tcaataaaac ccaatctatt atgaaaatca
    18121 aaaacacttt ccaactgaaa gaactacctc cagtgacaaa ctttgagaaa aacggtagta
    18181 gagctaaaaa gagaagtaaa ataggaagca tccgcattgt taaaatccgt ttggcataaa
    18241 aaaatcttta tttaaactaa aatattatag caaaatttac gccagttttt gaacggctga
    18301 tgtagatatt ttatactttc aaaatgttta aatgtgatta tttatttttg aaaaatagct
    18361 caccagcccg actgaaagtg cttatagaat gataataagt cgcctgccga aaacagcgaa
    18421 aaatagcggt gttatgcgga gataatctga cgcgatgcga aagtatattg catacttatt
    18481 ttcaacaatt tagcagagta tttttataag tgtgatataa tagaagtata atttgttctg
    18541 atagtttatt ttatggagaa gtagattttt agaatgcgga gggttcaata tggttgagtt
    18601 tataaagtct aagaaagaaa tgagtgagga ggatattaaa gcaaatttca tcactcctgc
    18661 tattgtatcc aaaggatgaa aaaatggtga gcatatcgct tacgaagaat acttcactga
    18721 tggtcgaatt gaagttagag gagataaggc tcgtcgtaaa gaaggaaaaa aatcagacta
    18781 ttcactgtat taccaatttg gaactcgaat tgcaattgtt gaggcaaagg ataataaaca
    18841 cagcgttcga gcaggattac aacaagctat tgaatatgga gagattttag atgttccatt
    18901 tgtttattct tcgaatggtg atggctttat tgaacacgac cgtatcacga gagaagaacg
    18961 tgagctggag ttagacgaat tccctactcg tgaagaatta ttttctcgta tgacgaagga
    19021 aaaaggattg acgtacgaaa ttacagaagc tatctcaact ccatactata cagacgcctt
    19081 ctcaatgaaa acgccacgct attatcagca aatagctatc aaccgtacta ttgaaacagt
    19141 tgccagagga caaaaacgag taatgtttgt gatggcaaca ggaacgggga aaacgttcat
    19201 ggcttttcaa attattcatc gccttcgaaa agctggtttg gctaaacgag ttttattctt
    19261 agcagataga aacatcttag tagaccaaac gatggctgaa gactttaggc cattcgaaaa
    19321 ggtaatgacg aaaattacac caaaactttt gactgctcct gaaaaattaa attcttttga
    19381 aatttatcta gggctttatc agcaactaac tggtgaagat ggaactgaaa cacattatca
    19441 aaaatttgac aaagacttct ttgatttaat cgtaattgat gaagcgcacc gtggttcagc
    19501 taaggaaaac agtaactggc gtaaggtaat tgattatttc agttctgcga cacagattgg
    19561 gatgaccgct actcctaaag aaaccaagaa tgcttccaat atggaatact ttggtgagcc
    19621 aatctatact tatagtttaa aacagggaat cgaggatggt tttttggctc catatcgtgt
    19681 tatgagggtt aatttagatg tggatgtggg tggttatcgt ccagaaactg gaaaagttga
    19741 tgctaacgga caattaatag aagataggta ctacggcagg aaagattttg ataaaaccat
    19801 tgtcattgat gatagaacgc aaagagttgc caagtttgtt tctgattata tgaagcaaaa
    19861 caatgcacga tttgataaaa caattgtttt ttgtgttgat attgaccatg ccgagcgaat
    19921 gcgtgctgca cttgtaaaag agaatctaga cttagtccaa gaagactatc gttatgtcat
    19981 gcaagtaact ggtgacaacg ctgaaggaaa agctcaactg gataacttta tggatgtcaa
    20041 ttctaatttt cccgctattg taacaacgtc taaattatta acgacaggag ttaatgctaa
    20101 aacatgtcgt ttgattgttt tagactctaa tatccaatcc atgactgaat ttaaacaaat
    20161 tattggtcgt ggcacacgtc tttatcctca aaaggggaaa gaatttttta cgattattga
    20221 ttttcgaaat gttaccaatt tgtttgctga ccctgatttt gatggtgatc cagtgaaggt
    20281 gctggaaaca ggtgcgaaaa cagtcagtgg ttctacgccc ggtttcgtag atgaggaagg
    20341 tgacccagta gaaaaatata tcgttacaga caagcaggtt accattctta attctactgt
    20401 tcaagtattg gatgaaaacg ggaaactgat taccgaaagc ctgaccgact acactcgaaa
    20461 gaatatctta ggtagctacg ccactttgaa cgattttatc acagtttggc atacggcaga
    20521 taagaagaag cttatcttag acgaacttta taaaaaagga gtttatctag atgctattcg
    20581 agagtcggag ggaatatcag aacaagaaat cgatgatttt gatttactcc taaaacttgc
    20641 ctatggtcaa aaagaattaa ccaaaacgga acgtatcaat aaactcaaac aaagcggata
    20701 tttatataaa tatagtgagg aagcgcgtgc tgttttggaa attttactga acaaatacat
    20761 ggataaaggt attggagaac tcgaaagcat tgaaacatta aaacttccag aatttcagat
    20821 atatggtgga accttcaaaa tcatcaatac ttattttgga gataaaaaac gatatttaca
    20881 agcaattaaa gaattggagc aagagctatt tacagtagct taatgaaagg aaagtatgtc
    20941 aattacatca tttgtaaaaa gaattcaaga tatcactcga aacgatgctg gtgttaatgg
    21001 tgatgctcaa cgtattgagc aaatgtcttg gttattattc ttaaaaattt atgatagccg
    21061 tgaaatggtt tgggaattag aagaagacga gtatgagtca attatcccag aggaattaaa
    21121 atggcgaaat tgggctcatg ctcaaaatgg ggaacgggta ttgacaggcg atgaattact
    21181 tgattttgtc aataacaagt tattcaaaga gttgaaagag cttgaaataa cttcaattat
    21241 gcctattcga aaaacgattg ttaaatcagc ttttgaagat gcgaacaact atatgaaaaa
    21301 tggcgtcttg ttacgccaag tcatcaatgt tattgatgaa gttgatttca atagccctga
    21361 agatcgtcat tcgtttaatg atatttacga aaaaattctt aaagatattc aaaatgctgg
    21421 gaactcagga gaattttata cgccacgtgc agcgactgat tttattgccg aagttcttaa
    21481 cccaaaactt ggagaatcaa tggcagacct tgcttgcgga acaggaggct tcttgacttc
    21541 gactctgaac cgtttaagta gtcaacgtaa aactagtgaa gataccaaaa aatataatac
    21601 agctgttttt ggtattgaaa agaaagcatt tcctcatctt ttagcagtta caaatctgtt
    21661 tcttcacgaa attgatgacc ctaaaattgt tcatggaaat actttggaga aaaatgttcg
    21721 tgaatatacg gatgatgaaa aatttgacat tattatgatg aatccacctt ttggagggtc
    21781 agaattagaa acaataaaaa ataactttcc agcagaatta cggagttctg aaacagctga
    21841 tttatttatg gctgtcatta tgtatcgttt gaaagaaaat ggtcgtgttg gagttatttt
    21901 acctgatggt tttctatttg gtgaaggtgt aaaaactcgc ttgaaacaaa aactggtaga
    21961 tgagttcaac ttgcatacga ttattaggtt gcctcatagt gtctttgcac cgtatacagg
    22021 aatccatacg aacattcttt tctttgataa aacaaagaaa acagaagaaa cttggtttta
    22081 tcgtttagat atgccagatg gttataaaaa tttctcgaaa actaagccga tgaagtcaga
    22141 acacttcaat cctgttcgtg actggtggga aaatcgtgaa gagattctgg aaggtaagtt
    22201 ctacaaatct aaatcattta cacctagtga attggctgag ttgaattata atttagacca
    22261 gtgtggtttt ccaaaagagg aagaggaaat cttaaatccc tttgagttga ttcagaatta
    22321 tcaagcggaa agagcaactt taaatcataa gattgataat gtattagctg atattttgca
    22381 gttgttggag gacaaataat gacaccagaa caacttaaag caagtattct ccaaagagcg
    22441 atggaaggga aattagtgcc gcaaaatccc aatgacgaac ctgcaagtga attattaaag
    22501 agaattaaag ctgaaaaaga aaaacttatc agtgaaggaa aaatcaaacg agataaaaaa
    22561 gaaactgaga tatttcgtgg tgatgatggg aaacattatg ggaagtttgc tgatggaagt
    22621 actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt gaggttttct
    22681 acattggttg aaattgtcag aggtggctct ccacgaccaa tcaaagatta tcttacttct
    22741 gaagtagatg gaataaattg gataaaaata ggtgatactg aaaagggtga aaagtatata
    22801 aataatgtta aagaaaaaat caaaaaatca gggcttaaca aaactagatt tgtaaaaaaa
    22861 ggtacatttt tgttaactaa ttctatgagt tttggtagac cttatatttt gaatgttgat
    22921 ggtgcaatac acgatggatg gttggctatt tcgaactatg aaaactcatt aaataaagat
    22981 tacctattct atattctttc atcaaatgta gtttattctc aatttctatc tctaattagt
    23041 ggagctgttg tgaaaaactt gaatagtgat aaagttgctt ctattcttat ccctctcccc
    23101 ccactatccg aacaacaacg aatagtagaa gcaatcgaat cagctttaga aaaagtagat
    23161 gaatatgctg aaagttataa tagactagaa cagctagata aagaatttcc agataaacta
    23221 aaaaaatcta ttcttcaata tgctatgcaa ggaaaattag ttgaacaaga cccaaatgat
    23281 gaatcagtcg aagttttact tgaaaaaata cgagcagaaa aacaaaaact ctttgaagaa
    23341 ggcaagatta aaaagaaaga tttggacatt tctattgttt cccaaggaga tgataactct
    23401 tattatgagg aagtaccttg tgaaatacca gaaagttggg aatgggtgag gttaaacgat
    23461 ataacctcct acattcaaag agggaagtct ccaaaatatt caaatattcc tatataccct
    23521 gtgattgctc agaaatgtaa tcaatggtct ggcttttcta ttgacttagc aagatttatt
    23581 gatcccgaaa cagttcatag ttaccagaaa gaaagattac taagggatgg tgatttaatg
    23641 tggaattcaa caggtctagg tacgttagga cgattagcta tttaccatga aaataaaaat
    23701 ccttatgcct gggctgttgc agatagccat gttacagtta taagagtctt atcgggggtt
    23761 attaattgcc atttcatcta taattttctt tcctctccta ttgttcagtc agttattgaa
    23821 gaaaaagcgt cgggtagtac aaaacaaaaa gaattattaa cgaaaactat aaaagaatat
    23881 ttaatccccc tcccacccct tcctgaacaa tccagaatcg ttgataaaat cgaacaattt
    23941 ttcgcccata ttgacgcact aatttagtat aatagtttta cgtgcggtgg aatttctatc
    24001 aaacataaga taggagtttt acgttgaaag attttgaatt acatttgaag aaagctggtt
    24061 tagctgaaaa tactgtgcgt tcgtaccttt atggtgttcg atttttcttg gagaattacg
    24121 aactcaaaat ggaagattta tttgaataca aaggatattt attagacaat tttaaaccta
    24181 aaactgtcaa tttgcgacta caaggagtaa ataaatatct ggcttttatt ggtcatgatg
    24241 atttgaaatt aaaatttgtc aaagtacagc aaaaaccgtt tttagaagat gtcattagcc
    24301 atgctgatta cctttttctt aaacgtagtt tgaaaaaaga tggtatttta aaatggcatt
    24361 ttgtcgtttg gtttttaggt gcaactgggg ctcgtgtaag tgaacttatt aaactaaaag
    24421 tagagcatgt agaaatcggt tattttgaca tttactcaaa aggtggtaaa attcgtagac
    24481 tgtacattcc taaaaaatta agaaatagtt gtcttagttg gttagaatca gaaaatcgtc
    24541 gaagtggtta tttatttttg aataaattta acgaaccaat tacagcaaga ggagttgctc
    24601 aacagttaaa aaattatgct gataaataca aaatgaatcc taaagtaatt taccctcatt
    24661 cttttaggca tttatttgct aagaattttt tagcgaagta taatgatatt gccttgcttg
    24721 cagatttgat gggacacgaa agtatagaaa ctactcgaat ttatctaagg aaaacagcta
    24781 ctgaacaaca aaatattgta gataaaattg ttaattggta aaaaataaca ggtggtcaaa
    24841 ctgactacct gctatttttg tgattatggc tcttattatg ggaacaaaga cgaaacatcc
    24901 tcttatccta tatatgaaat cccagaagca tggagatata ttaaatttgc tagcctagtt
    24961 aacttcagaa taggaaaaac tcctccacgc agtgaagcta ctttttgggg aactgaaata
    25021 ccctgggtat ctatatcaga tatgcctata tctggttatg taactaatac gagagaatct
    25081 atttctaaat tagcattaaa atcaaagaaa atagacattt cacctaaagg aactttatta
    25141 atgagtttta aattatctat tggaaaagtt gccatattgg atattcctgc cactcataat
    25201 gaagccatta tatcgatatt cccctatgct aataaagaaa atattatcag agattactta
    25261 atgatatttt tgccacttat ctctacttta ggtgattcaa aagatgctat caaagggaaa
    25321 acattaaata gtaccagtat ctccgaatta ttaatcccta tttctaatca tgaagagatg
    25381 aaaagaatca tttccaaagt tgatttactt tttcaaaaag tttctcaact ttttgagtaa
    25441 taagttcctg ttcctcaaaa ggagctaacg gaattaatag ctcgcttagt gtagttttag
    25501 gaatattata taaagcttga cctgatagtt tagttattgc tttcaattgt ttataaaata
    25561 acggagagga caagttaaat aatagaaatt ttgaaataat ctctgaactt tcgaatggtg
    25621 ttaattggaa aataaatcca ccagccacaa caccatcata gtctttatcg attcttgcaa
    25681 actttccaat atgttctaaa gaggttgata caggtgttat tagctgatta tgttttaaat
    25741 aaacttgctc agaggagatg aattgtgtat caatgtagta atcattatcc aacagagaaa
    25801 attctaaagg cttaatatta ccaccacgta taattctaac acctttatta ttaatgctta
    25861 aatcgccctt cttgtaagaa agacctgtat tcattgaaaa aatatctttt atttttataa
    25921 caacccaatt cataggtat
//
LOCUS       DAVLMQ010000023        25821 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000023 DAVLMQ010000000
VERSION     DAVLMQ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25821)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25821)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25821
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.023"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            454..1497
                     /locus_tag="VXF95_001194"
     CDS             454..1497
                     /locus_tag="VXF95_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HEV1081746.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGYNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFYTESEEQ"
     gene            1664..3751
                     /gene="topA"
                     /locus_tag="VXF95_001195"
     CDS             1664..3751
                     /gene="topA"
                     /locus_tag="VXF95_001195"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HEV1081747.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEVASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMVVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            3857..4216
                     /locus_tag="VXF95_001196"
     CDS             3857..4216
                     /locus_tag="VXF95_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HEV1081748.1"
                     /translation="MRLIYLIIGFLSLTLAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYILMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            4309..4941
                     /locus_tag="VXF95_001197"
     CDS             4309..4941
                     /locus_tag="VXF95_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HEV1081749.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGALTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLDNRQTFIDQVGVTQLHGTKVVF"
     gene            4985..5641
                     /locus_tag="VXF95_001198"
     CDS             4985..5641
                     /locus_tag="VXF95_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HEV1081750.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMTGSFVASVREACLEILYQIRKTCFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            5660..6292
                     /locus_tag="VXF95_001199"
     CDS             5660..6292
                     /locus_tag="VXF95_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HEV1081751.1"
                     /translation="MNFQLAKYSLLKKFSENIGFTTLEEYGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVFRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            6320..6754
                     /locus_tag="VXF95_001200"
     CDS             6320..6754
                     /locus_tag="VXF95_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HEV1081752.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            6766..7803
                     /gene="leuB"
                     /locus_tag="VXF95_001201"
     CDS             6766..7803
                     /gene="leuB"
                     /locus_tag="VXF95_001201"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HEV1081753.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAWPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNIYAN
                     IRPVKIFDSLKHLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKIVTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLGVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPISMILSVVMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            7800..8069
                     /locus_tag="VXF95_001202"
     CDS             7800..8069
                     /locus_tag="VXF95_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HEV1081754.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIQEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            8073..8432
                     /locus_tag="VXF95_001203"
     CDS             8073..8432
                     /locus_tag="VXF95_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HEV1081755.1"
                     /translation="MAGSSREHAAWALANYGFKVVIAGTFGDIHYNNELNNGMLPIVQ
                     PREVREKLAQLKPTDHVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIAAYEKQRPAYWQD"
     gene            8651..8794
                     /locus_tag="VXF95_001204"
     CDS             8651..8794
                     /locus_tag="VXF95_001204"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081756.1"
                     /translation="MTSDKAGLERKFAAKERKRNKPGVVLCGSMDELCALAQLNPEIE
                     AFY"
     gene            8813..9067
                     /locus_tag="VXF95_001205"
     CDS             8813..9067
                     /locus_tag="VXF95_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081757.1"
                     /translation="MLLGCILPWKPEAFEKLKAYGDGREELMTDVRGTSCFVIKFGKA
                     GEQLAAKLWEEGKMVYASYASMTKRLKLAMRARCNGVYGR"
     gene            9057..9218
                     /locus_tag="VXF95_001206"
     CDS             9057..9218
                     /locus_tag="VXF95_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081758.1"
                     /translation="MVDKDGKLIPEQGGARSTSPAPVVIRKGLDIDKIMMHLSDTFNS
                     WDYRQREYY"
     gene            9383..11314
                     /locus_tag="VXF95_001207"
     CDS             9383..11314
                     /locus_tag="VXF95_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HEV1081759.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYTEGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFSHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     PQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFDLTNNEQ
                     KDQAVADDNEGDENDDADY"
     gene            11301..12617
                     /locus_tag="VXF95_001208"
     CDS             11301..12617
                     /locus_tag="VXF95_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HEV1081760.1"
                     /translation="MRITDNQHKIIKEKFVEEYPKLSNPLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYHRFSHNDSHVKGV
                     IDVRSHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIENQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASSYSAFCKMMENSEENFKAIIDEEVGRK"
     gene            12792..13778
                     /locus_tag="VXF95_001209"
     CDS             12792..13778
                     /locus_tag="VXF95_001209"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HEV1081761.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKTDAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMVMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            13842..13913
                     /locus_tag="VXF95_001210"
     tRNA            13842..13913
                     /locus_tag="VXF95_001210"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13875..13877,aa:Arg,seq:ccg)
     gene            14096..14794
                     /locus_tag="VXF95_001211"
     CDS             14096..14794
                     /locus_tag="VXF95_001211"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HEV1081762.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            14785..18324
                     /gene="smc"
                     /locus_tag="VXF95_001212"
     CDS             14785..18324
                     /gene="smc"
                     /locus_tag="VXF95_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HEV1081763.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELAQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAVLEDKRNS
                     LSQEKSDKESSLVLLEENLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLATAKEKASQQKDELETAKVQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAASAGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARKVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAEEEASLRSDEVSLKNLQDELARLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEELNRLSEGEWQADKEKCQERLTTITSEKNNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVTDIERLGKELDNLDIEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNLQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELDNLNLAEQEVQDLEK
                     AIRSLGPVNLDAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPPGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            18321..19115
                     /locus_tag="VXF95_001213"
     CDS             18321..19115
                     /locus_tag="VXF95_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1081764.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFAGVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNEHVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            19115..19933
                     /locus_tag="VXF95_001214"
     CDS             19115..19933
                     /locus_tag="VXF95_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1081765.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKETLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISPELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            19937..21214
                     /gene="ftsY"
                     /locus_tag="VXF95_001215"
     CDS             19937..21214
                     /gene="ftsY"
                     /locus_tag="VXF95_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HEV1081766.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVEEVS
                     QEEAEVEIVEQAVFQEEEIQDTVEESLDLEPVVEVSQKEVEEFPHSEEGNTEFLETVE
                     ENNSEILEAERPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEELEEL
                     LIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQ
                     DNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWGRRVD
                     VPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGRIIKR
                     VVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREEL
                     NIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(21260..22747)
                     /locus_tag="VXF95_001216"
     CDS             complement(21260..22747)
                     /locus_tag="VXF95_001216"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HEV1081767.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYKSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     DELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRSVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDITYRQDGRLE"
     gene            complement(22896..23636)
                     /locus_tag="VXF95_001217"
     CDS             complement(22896..23636)
                     /locus_tag="VXF95_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1081768.1"
                     /translation="MAKLKIDVNDLHKHYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEKLGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(23636..25801)
                     /locus_tag="VXF95_001218"
     CDS             complement(23636..25801)
                     /locus_tag="VXF95_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HEV1081769.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
BASE COUNT         8034 a         4549 c         5731 g         7507 t
ORIGIN      
        1 tttagtgtaa ttgagaaagg agaaatgatt gtgattgatg ttggctaggt tatgttcaat
       61 gattcctacc gtctcaaatc ttgtcagtaa ggaaaaataa attcttcaaa agtagagatt
      121 acaaggcttg tttaagaaag aattcaaaga ccttgacaaa taaaaataaa atggttatta
      181 taagaaatgg tctaaaatag atgatgatac ttttcgaaaa tctttttacg tcagctcagc
      241 tttgccttgc tgtgttttga gcaagctacg gttagcttcc gagtttgatt ttcatttact
      301 agaaatgaaa ctgatgagag atatcagtag acatttgagt caggatatta tggaaaatga
      361 taaaaagagc ttgtgagatt ggcatatcag actactaaag tattgagttt gttaggattt
      421 tagcgactag ttagctggga aaggaagata tttgtgacaa ataataaact gtattcgttg
      481 atagaattta gaaataaaat atatgaagaa ttagaacttt ccagaagtga tttagcgatt
      541 ttactatgtg ccatgcttat cgcctctatc ggattaaata tggattcgac tcccgtgatt
      601 attggagcca tgttaatctc tcctttgatg acacctattc tgggagtggg gctctctcta
      661 gctatatttg attttaaatt gttaagaaaa tcttttaaaa tattagctat tcaaattctt
      721 gccagtctaa tagcttcaac actttatttt tatctttctc ccatttcgta tgctagttcg
      781 gagattgttg ctagaacctc tccgactatt tgggatgttc tcattgcttt tgtaggaggg
      841 atagcaggta ttattggtgc taggaaaaaa gagaccaata atattgttcc tggtgttgct
      901 attgcaaccg ccttgatgcc tcctctttgt acagtaggtt atgctattgc ttctgctaat
      961 ctaaaattta tcataggctc ctcttaccta ttcctcatca attgtagctt tattgtcatt
     1021 gcgacttata taggtgttag gttgatgatg gttaagaaac attattttaa agataatgaa
     1081 gaagactcta aaatgcgtag gattttgctt ctagttgctg ttttgctgat gattccgagt
     1141 ttcatctctg caacgacttt agtgagagaa acgttgaaaa aagagtccct taagaaattt
     1201 atatcagagc agtttcaggg gtataatatt ttgaaaaaaa cctattctaa aaagactcat
     1261 accctaaagc taaccatttc aggaaattat ttgacagaag aagaactcga tatgatttca
     1321 agtaagagag gtgactatgg tttaagtgat gtttctgttc aagtttcaca attgtctgat
     1381 tcagaacaac ttagtaagga agagctggtg gagtatttct tccagtatat caaggataag
     1441 gaagcaaaag aaaaggaaaa agctaataag ttttatacag agtctgagga gcaataattt
     1501 cttgagaata gctggttttt ctcgtgagtc ttctatgtat atcaaaggaa gactgaggtt
     1561 ttaagtataa aacttttctt ctattatagt agctaagtct tgacagggtt caaaaaatgg
     1621 tttacacttt ataaagttta ttactttgaa aaggtgtgat actgtggcta cggcaacaaa
     1681 aaagaaaaaa tcaacagtta aaaaaaatct agtcatcgtg gagtcgcctg ctaaggccaa
     1741 gacgattgaa aaatatctag gcagaaacta caaggtttta gccagtgtcg ggcatatccg
     1801 tgatttgaag aaatccagta tgtccgtcga tattgaaaat aattatgaac cgcaatatat
     1861 taatatccga ggaaaaggcc ctcttatcaa tgacttgaaa aaagaagcta aaaaagctaa
     1921 taaagttttt ctcgcgagtg acccggaccg tgaaggagaa gcgatttctt ggcatttggc
     1981 ccatattctc aacttggatg aaaatgatgc caaccgtgtg gtcttcaatg aaatcaccaa
     2041 ggatgcagtc aaaaatgctt ttaaagaacc tcgtaagatc gatatggact tggtcgatgc
     2101 ccaacaagct cgtcggatct tggaccgctt ggtagggtat tcgatttcgc ctattttgtg
     2161 gaagaaggtc aagaagggct tgtcagcagg tcgcgttcag tccattgccc ttaaactcat
     2221 cattgaccgt gaaaatgaaa tcaatgcctt ccagccagaa gaatactgga cagttgatgc
     2281 tgtctttaaa aagggaacca aacaatttca tgcttccttc tatggagtag atggtaaaaa
     2341 gatgaaactg accagcaatg acgaagtcaa ggaagtcttg tctcgtctga cgagtaaaga
     2401 cttttcagta gatcaggtgg ataagaaaga gcgcaagcgc aatgctcctt taccctatac
     2461 cacttcatct atgcagatgg atgctgccaa taaaatcaat ttccgtactc gaaaaaccat
     2521 gatggttgcc caacagctct atgaaggaat taatatcggt tctggtgttc aaggtttgat
     2581 tacctatatg cgtaccgatt cgactcgtat cagtcctgta gcgcaaaatg aggtggcaag
     2641 cttcattacg gatcgttttg gtagtaagta ttctaagcac ggtagcaagg tcaaaaacgc
     2701 atcaggtgct caggatgccc atgaggctat tcgtccgtca agtgtcttta atacaccaga
     2761 aagcatcgct aagtatctgg acaaggatca gctcaagcta tataccctta tctggaatcg
     2821 ttttgtggct agccagatga cagcggccgt ttttgatacc atggctgtta aattgtctca
     2881 aaaaggggtt caatttgctg ccaatggtag tcaggttaag tttgatggtt atcttgccat
     2941 ttataatgat tctgacaaga ataagatgtt accggacatg gttgttggag atgtggtcaa
     3001 acaggtcaat agcaaaccag agcaacattt cacccaaccg cctgcccgtt attctgaagc
     3061 aacactgatt aaaaccttag aggaaaatgg ggttggacgt ccatcaacct acgcgccaac
     3121 cattgaaacc attcagaaac gttattatgt tcgcctggca gccaaacgtt ttgaaccgac
     3181 agagttggga gaaattgtca ataagctcat cgttgaatat ttcccagata tcgtaaacgt
     3241 gaccttcaca gctgaaatgg aaggtaaact ggatgatgtc gaagttggaa aagagcagtg
     3301 gcgacgggtc attgatgcct tttacaaacc attctctaaa gaagttgcca aggctgaaga
     3361 agaaatggaa aaaatccaga ttaaggatga accagctgga tttgactgtg aagtgtgtgg
     3421 cagtccaatg gtcattaaac ttggtcgttt tggtaaattc tacgcttgta gcaatttccc
     3481 agattgccgt catacccaag caatcgtgaa agagattggt gttgagtgtc caagctgtca
     3541 tcagggacaa attattgagc gaaaaaccaa gcgtaatcgc ctcttctatg gttgcaatcg
     3601 ctatccagaa tgtgaattta cctcttggga caagcctgtt ggtcgtgact gtccaaaatg
     3661 tggcaacttc ctcatggaga aaaaagtccg tggtggtggc aagcaggttg tttgtagcaa
     3721 aggcgactac gaggaagaaa agattaaata agaggagggg cccgaaagta aatttcaggc
     3781 tccttttggt tagaacttga caaaatacat cattttatgc gaaactagaa gaagattatt
     3841 ttaactagga gaagttatgc gtcttatcta tctgataatt ggttttttat cactgacctt
     3901 ggctattgtt ggggttgttt tacccttgtt gccgacaacg cctttccttt tgttgtctat
     3961 tgcttgtttc tccagaagtt ccaagcgttt cgaagactgg ctttatcata ccaagctcta
     4021 tcaaacatat gtagctgatt ttcgcgagac taagtctatt acgcgtgaac gaaagaaaaa
     4081 aatcatcgta tccatttaca ttttgatggg gatttctatt tattttgccc ctctcttacc
     4141 agtcaaaatc ggtctgggtg ctttgaccat ctttatcact tattatcttt tcaaggtcat
     4201 tccagacaaa gaatagttaa aacagtagtt atttgccttg ataaaattga aagcatattc
     4261 ataacaatat gatataataa atttgaagta atattcaagg agaatcaaat gatttacgaa
     4321 ttttgtgctg aaaatgtgac tttacttgaa aaagcgatgc aggctggagc tcgtcggatt
     4381 gaactctgtg ataatctagc agttggtggg acaacaccca gctatggagt gactaaggca
     4441 gcggttgaac tggcagctaa ctacgataca accatcatga ccatgattcg gccacgtggt
     4501 ggtgactttg tctataatga cctagaaatt gctatcatgc tagaagacat tcgtttgact
     4561 gctcaggctg gaagtcaagg ggttgtattt ggagctttaa ctgctgataa aaagttggat
     4621 aagcctaatc tggaaaagtt aattgctgca tcaaaaggaa tggaaattgt ctttcacatg
     4681 gcctttgatg aactaagtga tgaagatcaa ccggaagcta ttgactggct cagtcaagcc
     4741 ggtgtcactc gtatcctaac tcgtgctggt gtgtctggcg actccttaga aaaacgtttt
     4801 gttcactatc acagaatttt ggagtacgct aaaggtaaaa ttgaaattct accaggtggg
     4861 gggattgacc ttgacaaccg tcaaaccttt atcgaccagg tgggggtaac acaattgcat
     4921 ggtactaagg ttgtttttta aaaaatagaa aggaactgct agctttgggt agcagttttc
     4981 acttatgttt gaaattttta aatcctatca atttaatcaa gaaaaggctc atgattatgg
     5041 ttttatagaa aatagcgaag tctggacata tagttgccag attttgcaag gtgactttgt
     5101 catgactgtg tccatcactg ctgataatgt gaactttcaa gtctttgacc aagagactgg
     5161 tgacctctat cctcacgttc atatggaaag tatgacagga agttttgttg caagtgtccg
     5221 tgaggcttgt ttggagattc tttaccagat acggaagact tgttttgatg tgcaagattt
     5281 tatctgtcat cagactaagc gtatcatgac tcaagttcag gaaaagtatg gaaaccagtt
     5341 ggagtatctg tgggaaaaat cgcctgatac agctgtattg cgccatgaag gcaatcaaaa
     5401 gtggtatgcc gtcttgatga aaatctcttg gaataagctg gaaaagggca gagaaggaca
     5461 agtggaagca gtcaacctca agcatgacca agtagctaat ttgctttcac aaaaggggat
     5521 ttatccagcc ttccatatga gcaagcgcta ctggattagt gtgtcccttg atgatacttt
     5581 atcagatgaa gaagtactgg aattgataga aaaaagttgg aacttaacct ctaaaaaatg
     5641 aaatatttta ataattttca tgaactttca attagctaaa tattctttac tgaagaaatt
     5701 ttcagaaaat ataggattta ccacactaga ggaatatggt gccatcttca aatacctgat
     5761 tgagaatgtc aagacggatc gtcagatcat ctattcgcct cactgtcatg atgacctcgg
     5821 aatggcagtg gcaaatagcc ttgctgctgt caagaatggt gcaggacgtg ttgaagggac
     5881 tatcaatggt attagggagc gagctgaaaa tgctgctttg gaagaaattg cagtggctct
     5941 caatattcgc caagattact accaagtaga aaccagtatt gtcctaaatg agaccatcaa
     6001 tacgtcagaa atggtttttc gcttctctgg tattccagtt cctaaaaaca aagccgtcgt
     6061 tggtggcaat accttctccc acgaatctgg tattcaccaa gatggagtcc ttaaaaatcc
     6121 tctcacttat gagatcatca cacctgaatt ggttggtgtt aagattccgc ttggaaaatt
     6181 atctggtcgc catgcttttg ttgagaaact gagagaattg gccctagatt ttacagaaga
     6241 ggatatcaaa ccactctttg ctaagttcaa ggcactggcc gataagaagt aagaaatcac
     6301 agatgcagat actcgagctt tggtagctgg aaccatggtt gaaaatccag aaggcttcca
     6361 ctttgatgat ttacaacttc aaactcatgc agataatgac attgaagcgc tcgttagcct
     6421 agccaatatg gatggtgaga aagtcgaatt taatgcgaca gggcaaggtt ccgttgaagc
     6481 aatctttaat gctatcgata agttctttaa ccaatctgtt cgtttggtgt cctacactat
     6541 cgatgcggta acagatggaa tcgataccca ggatcgggtt ttggtcactg ttgaaaacag
     6601 agatacagaa accatcttta atgcagcagg gcttgatttt gatgtgttga aggcttctgc
     6661 tattgtctat ataaacgcta atacctttgt tcaaaaagag aatgcaggtg agatgggacg
     6721 cagtgtttct taccacgata tgcctagtgt gtaaaggaga aggctatggc aaagaaaata
     6781 gtagctctag caggagacgg aattggccca gaaatcatgg aggttggttt agaagttctg
     6841 gaggctctag ctgaaaaaac aggttttgac tatgagattg acagacgacc gttcggaggt
     6901 gcagatattg atgcagcatg gcctccctta cctgatgaaa cccttaaggc aagtagggaa
     6961 gcagatgcta tcctactagc agctatcggt agtcctcagt atgatggagc agtggttcgc
     7021 cctgaacaag gcctgatggc tctccgtaag gaactcaata tttacgctaa tattcgtcct
     7081 gtaaaaatct ttgacagtct caagcatttg tcaccactca aactggaacg aattgctggt
     7141 gtagactttg tcgtggtgcg tgaattgaca ggcgggattt actttggaga tcatattctt
     7201 gaagagcgca atgcgcgtga tatcaacgac tatagctatg aggaagtgga gcggattatt
     7261 cgcaaagcct ttgaaattgc aagaaatcgc agaaaaatcg ttactagtat cgataagcaa
     7321 aatgttctag cgacctcaaa actctggcgg aaggtagctg aggaagtcgc acaggatttc
     7381 ccagatgtaa ccttggaaca tcagctggta gactcagctg ctatgcttat gattaccaat
     7441 cctgctaagt ttgatgttat tgtaacggag aatctttttg gagatatttt atctgatgaa
     7501 tcaagcgtct tatctggtac acttggggtt atgccatcag ccagtcattc tgaaaatgga
     7561 ccaagtctct atgaacctat tcacggttca gcacctgata ttgcaggtca aggaattgcc
     7621 aatcctattt ccatgatttt atcagttgtc atgatgttga gagatagttt cggacgttat
     7681 gaggatgcag agcgtatcaa acgtgctgtt gagacaagtc tggcggcagg aattttaacg
     7741 agagatatag gaggtcaggc ttcaacaaag gaaatgacgg aagctattat tgcaaggtta
     7801 tgaagttaga cgaaaaaatt actctagtcc ttttgatttg gaatgtcatc attttcttga
     7861 tttatggcat tgacaaattc aaggcaagaa gaagagcttg gcgcatccaa gagaaaatct
     7921 tactcatttt agcccttact tgtggtggtt ttggggcctg gttagctgga atcacttttc
     7981 accacaagac tcgaaaatgg tactttaaaa cagtttggtt tcttgggatg gtgactacac
     8041 tagtagcctt atattttatt tggaggtaat ggatggcagg gtcttcgagg gaacacgctg
     8101 cttgggctct agcgaactat ggttttaagg tcgtgattgc aggaactttc ggtgacattc
     8161 attacaataa tgaactcaat aatggcatgt tgccaatcgt tcagcctaga gaggttagag
     8221 agaaactagc ccagctaaaa ccaaccgacc atgtaactgt ggacttggaa caacaaaaaa
     8281 tcatctcacc agttgaagaa ttcaccttcg agatagatag cgagtggaaa cataaactcc
     8341 taaatagttt ggatgatatc ggtattacct tgcagtatga agagttgatt gctgcttatg
     8401 aaaaacaacg accagcctac tggcaggatt agaaaaaata gaaaaggaaa tatagtaaac
     8461 tgaaataaga tgtaaacaaa tgaattagag cttaacatcc atttccagca attttttaga
     8521 aactacagtg gactattctg gattcaacac attataaaat tatgacaaaa cacattcaca
     8581 agaaggctac gacattttaa aaggtgaggg tggatgtatc gtttgcccta ctaaagttgg
     8641 ttacattatc atgaccagtg ataaggcagg acttgagcgt aagttcgcag ccaaagaacg
     8701 taagcgtaac aaaccaggtg ttgttctctg cggtagcatg gatgaacttt gcgctttagc
     8761 gcaactcaac ccagaaattg aagcattcta ctaaaaacat tgggatgaag atattcttct
     8821 tggttgtatc cttccttgga aaccagaagc ctttgaaaaa ctcaaagcat acggggatgg
     8881 ccgtgaagaa cttatgactg atgtacgtgg tactagctgt tttgttatca agtttggaaa
     8941 agcaggtgaa caattggctg ccaagctttg ggaagaaggt aaaatggtct acgcctcata
     9001 tgcttcaatg acaaaacgat tgaaactcgc tatgagagca aggtgtaatg gtgtctatgg
     9061 tcgataagga cggcaaactc atcccagaac aaggaggagc acgttcaacc tcaccagcac
     9121 cagttgtgat ccgtaaaggg cttgacattg ataaaatcat gatgcacctg tcagacacct
     9181 ttaactcatg ggattaccgt cagagagagt attattagga taaaaaagaa gtctagtgtt
     9241 atgagatatt aaagctccta acactgggct ttttgtttag aatttctttt ctttttctat
     9301 aggatatggt attctatgta gaaaatatat gttaataagt aatgccaata tttaaacatc
     9361 attagtaaaa ggagttagat tgatgaataa aagaaaagtt agtttagaag atttttataa
     9421 atggtatagt ctaaataaag aagagttatt aaataaggca actgttggtg aaaagtttaa
     9481 tgataaatta aaagaagagt ttctccagga atggcctttg gataggattt taacaatgtc
     9541 aatcgatgaa tatgtaatag gaaagggaca gcaaaataag tctttatgct acgctcttga
     9601 gaagggaaaa tacaaaaatc tatttcttgg aatttctggt ggctcagctt caaaatttgg
     9661 tatttattgg aataaaaaaa caaacaaata taaagatcaa gctaataatg agatttcaga
     9721 gttggatcag cgattttcaa aattaaaatc agatttgtat gaaattatca aagaaggtat
     9781 tcgttttaac tttgaaaatc ctatttttga tatgaaaaga tcaacaaatg aatttattgg
     9841 tcgttctgct atggtgacaa aattactttg tatctatact gagggagatc ctttctttgg
     9901 tgtaaatatt aatagtcaga aagaattttg gaaccacttt gtttctcaga caaatcaagg
     9961 tggaccttat ctgcaaaatc ataaaataat tgaactggtg tccaaaactt atcctgagtt
    10021 ggagccatcg aaattaggaa ctatgctttt tgagtattct aagcttttta tggaaaataa
    10081 ggaagacaat agtacaatgg attcatcaaa caattttagt catcaattaa ctcaatctct
    10141 attaaagtct ccaaacctta tccttcgtgg tgctcctggc acaggaaaga cttatcttgc
    10201 taaagaaatt gccaaagaat taacggatgg caacgaagac caaatcggat ttgtacaatt
    10261 tcacccatcc tatgattata cggattttgt agaaggttta agaccagtat caaatgggga
    10321 tggagctatt gagtttaggc tacaggacgg tatttttaaa gatttttgtc agaaagcaaa
    10381 agaaccccaa ttgattggag gacaagataa ttttgatgag gcttgggatt cttacttaga
    10441 atatataaat gttgctgaag aaaaagaata tataacaaaa acatcttact tatctgttaa
    10501 tagtagacaa aatttgtcag taaattatga tagtggtgtt ccaggatggt cactacctag
    10561 caaatatgtt tacgagttgt ataaagataa aaattataat aagcaagaat actacaaaag
    10621 tggtggaaaa actgtcctag aaacattgag aaagagattt ggtttgaaag actatgtttc
    10681 cccaacagaa attgatactg ataagaaatt cgtcttcatc atcgatgaaa tcaatcgtgg
    10741 ggagatttct aagatttttg gcgaactctt tttctctatc gaccctggct atcgtggtga
    10801 aaaaggaagt gtttctaccc aatatgcaaa tctacacgaa actgatgaaa agttctatat
    10861 ccccgaaaat gtttacatca tcggaactat gaatgatatt gatcgttcag tggatacctt
    10921 tgattttgct atgcgtcgtc gttttcgttt tgttgaagtt actgccgagg gtcaagttgg
    10981 catgttggat aaagagttga atatccatgc agaagaagca aaaattcgtc taagaaactt
    11041 gaacgctgct atcgaaaatg ttcaggaatt aaacagtcat tatcatattg gaccaagtta
    11101 ttttcttaag ttgaaggatg tagattttga ctatgaatta ctctggtctg attatattaa
    11161 gcctctccta gaagactact tgcgaggttc ttatgatgag gttgaaactt tggaaacttt
    11221 gaaaaaagca tttgatctga caaataatga gcaaaaagat caggcagtag ctgatgacaa
    11281 tgaaggcgat gaaaacgatg atgcggatta ctgataatca acacaagatt attaaagaaa
    11341 aatttgttga agaatatcct aaactaagca atcctctttt agacagaacc ttggaaagtc
    11401 tatcccaaga tgaacgtatt ttcatttttc caaatgattt gactcatact cctgatttgg
    11461 ataaggacca aaagattttt gaaacagtca atcagaaaat taagacaggg aacgtgattg
    11521 gttttcttgg atatggtcag gaaagattaa cgatttcctc acgattttct gatgagagta
    11581 atgaccattt tttgcattat ctcttaaaca aggttcttca tatcaatctc actagtttag
    11641 atgttgcttt gtctcgtgaa gagaggcttt atcaactttt gatgtatctc ttccccaagt
    11701 atctacaagc tgctattcga aaaggtcttt ataaggaata tcatcgattt tctcataacg
    11761 acagtcatgt taagggagtg attgatgtaa gaagccatct caagaaaaat cttcctttca
    11821 cgggaaatat tgcctacaca acgagagagt tcacctatga taatcccctc atgcagttgg
    11881 tccgtcacac tattgaatac attgagaatc agaaaagcat tggtcaaggg gtactagata
    11941 atctctcaac tagtcgtgaa aacgtatctg aaatcgtgcg tgtaacgccc tcttataaac
    12001 tagctgatcg tgctaagatt attcggggaa atcaatctaa acctatacgt catgcatact
    12061 ttcacgagta cagaaactta caagaacttt gtctgatgat cctaaaccaa gaaaagcacg
    12121 gtttagggta tcaagatcaa aaaatctatg gtattctctt tgatgttgcc tggctttggg
    12181 aagagtatgt ttacaccttg ttgccaaaag gttttgtaca tcccagaaat aaggataaga
    12241 cggatggaat ttcagtattt tctgttggga aacgaaaagt atatccagat ttttatgaca
    12301 gagaacgaaa gattgttcta gatgcaaaat ataaaaaact ggaattgact gaaaaaggaa
    12361 tcaaccgtga ggacttattc cagctgattt cctattctta tattttaaaa gctgagaagg
    12421 ctggactgat ttttcctagt atggagcagt cagtaaatag tgaaatagga aaagtagctg
    12481 gctatggagc tcaattgaag aagtggtcta ttcgaatccc tcagaatgcc tcatcctata
    12541 gtgcattttg taaaatgatg gaaaattcag aagaaaattt taaagcgatt attgatgaag
    12601 aagtggggag aaaataattt cccctctttc ttttattttt aacacaagca aaacccgaac
    12661 gatatatttt aattcataaa ataatttgac aaaaactgta ctttggttta taataaatta
    12721 aggaaacgtc ggaaaaggcg tagtgatgcg agagcatagg taggtcatta caaaagaaac
    12781 gagacatcga tatgttaaat gaatttccaa tttttgatta cgaagatatt caattgattc
    12841 caaataaatg tgtcattaaa agccgtgcag aagcggatac aagtgtcact ttaggaaatc
    12901 acacctttaa actacctgtt gtgccagcga atatgcagac gattttggat gaaaatgtag
    12961 cagagcaact ggctaaaggt ggttacttct acattatgca ccgttttgat gaggcaggac
    13021 gcattccttt tattaaacga atgcacgatc aagggctcat tgcttccata tctgtcggtg
    13081 ttaaggacta tgagtatgat ttcgttagac agctcaagac tgatgctcct gagtatatca
    13141 ctattgatat tgctcatggt catgcggata gcgtgatttc tatgattcaa cacatcaaga
    13201 aagaattgcc agataccttt gtaattgctg gaaatgtggg aacaccagaa gctgtgcgtg
    13261 aattggaaaa tgctggtgcg gatgctacta aggtcggaat cggtcctggt aaggtttgta
    13321 tcaccaaggt taagactggt tttggtacag gtggttggca gttggctgct ctacgctggt
    13381 gtgccaaggc tgcgcgtaaa ccgattatcg ctgatggagg aattcgtact cacggtgata
    13441 ttgccaagtc tatccgcttc ggtgctagca tggtcatgat tggttccctc tttgcaggac
    13501 acattgaaag tccagggaaa acgattgaag tcgatggtga acagttcaaa gaatattatg
    13561 gttcagcctc acaatatcaa aaaggtgctt acaaaaatgt ggaaggcaaa cgtatcttgc
    13621 ttcctgctaa aggtcatctg caagacactt taactgagat ggaacaagac cttcaaagtg
    13681 ctatttctta tgcaggtgga cgtcaggttg ctgaccttaa acacgttgat tatgtgatcg
    13741 tgaaaaactc catctggaat ggggatgctt cccactaaga cggggtcttt gaccaaaaaa
    13801 cttgttatta gagcaaattt ctgttataat aaaacaagtt tccaccctta gtgtaatgga
    13861 tatcacgtaa gattccggtt cttgagatgg gggttcgatt ccctcagggt ggatgtaaac
    13921 atcctaaaaa gcctttaata gggctttttt ctttatcctg acccaaattt gccgctaaaa
    13981 ctgagaatct ctgtctaaag aattcccaaa tgctttccag tcccgtttta gagtgactca
    14041 gggggctttt tttgatataa taaaaaggac tattatcagt tagaaagagg ttggtatgaa
    14101 agaattacaa actgtactaa agaatcattt tgcaatcgaa tttgcagaca aaaatttact
    14161 ggaaactgcc tttactcata cgagttatgc caatgagcac cgcctcttaa aaatttcaca
    14221 caatgaacgc ttggaatttt taggagacgc tgttctacag ttattgattt cagaatatct
    14281 atataaaaaa tatcctaaaa agcctgaagg tgacctatca aaactccgtg ctatgattgt
    14341 ccgtgaggag agtttagctg gttttgcgcg tgattgccag tttaaccagt ttatcaagtt
    14401 gggtaaaggg gaagaaaaat caggtggtcg caatcgtgac accattcttg gtgatgcctt
    14461 tgaagccttt cttggtgccc ttcttttgga taaggatgtg gccaaggtca aggaatttat
    14521 ctatcaagtc atcattccta aggttgaagc aggcgagttt gagatgatta cagactataa
    14581 aacccatctc caagagttgc ttcaggtcaa tggtgatgtg gctattcgtt atcaggtgat
    14641 ttctgaaaca gggcctgctc atgataaggt ctttgatgta gaagttcttg ttgaaggtaa
    14701 gagcatcggt caaggccaag gtcgttctaa gaaattagca gagcaggaag ctgccaaaaa
    14761 tgccgttgag aaggggctgg attcatgtat ttaaaggaaa tcgaaattca ggggttcaag
    14821 tcttttgctg ataagaccaa ggtcgttttt gaccaaggtg tgacggcagt tgttggaccc
    14881 aatggatctg gaaagtccaa tattacagaa agtctgcgtt gggctttggg ggagtctagt
    14941 gtcaagagtc tccgtggggg caagatgccg gatgtcatct ttgctggaac cgaaagtcgc
    15001 aaaccgctca attatgcttc tgtagttgtg actctggata atcatgacgg atttatcaag
    15061 gatgcaggtc aagaaatcag ggtggaacgc catatctatc gtagtggaga tagcgaatac
    15121 aagattgacg gcaagaaagt ccgtctgcgt gatattcatg acctcttctt ggatactgga
    15181 ttgggacgag attccttctc tattatttcc caagggaagg ttgaggagat ttttaattcc
    15241 aagcctgagg aacgacgagc tatttttgaa gaagctgctg gagttttaaa atacaagact
    15301 cgcagaaaag aaaccgagag taaactgcag caaactcagg ataatctgga ccgcttagag
    15361 gacattatct acgagttgga taatcaaatc aagcctcttg aaaagcaagc tgagaatgcc
    15421 cgtaagtttt tagacttgga aggacaacgt aaggctattt atttagatgt tctggttgct
    15481 caaatcaagg aaaataaggc tgaactagag tcgacagaag aagagttggc tcaggttcaa
    15541 gaactcttga tgagttatta ccaaaagcgt gaaaaattag aagaagaaaa tcaaactctt
    15601 aaaaagcaac gccaagattt acaggctgaa atggccaaag accaaggcag tttgatggat
    15661 ttgaccagtc tgattagtga tttagagaga aaattagccc tatcgaaatt agaatctgag
    15721 caagtagccc tgaatcaaca ggaagcacaa gctcgtttgg ctgttttgga ggataagaga
    15781 aattcactca gccaagaaaa atctgataaa gaaagctctt tagtactttt agaggaaaat
    15841 ctagtccaaa ataatcaaaa actcaatcgt ttagaagctg aattgctagc tttttcagat
    15901 gatcctgatc agatgattga gctcttacgt gaacgctttg tagctctttt acaagaagaa
    15961 gcggatgtct caaaccaact gacccgcatc gagaatgagt tggaaaatag tcgtcagctt
    16021 tctcaaaaac aagcagatca actagaaaag ctgaaagagc aattagctac agctaaagag
    16081 aaggctagtc agcaaaaaga cgagcttgaa actgccaagg tgcaggttca gaaattattg
    16141 gctgactatc aagctattgc caaggagcaa gaggagcaaa aaacttccta tcaagctcaa
    16201 caaagtcaac tctttgaccg tctggatagt cttaaaaaca agcaggctag agctcaaagt
    16261 ttggaaaaca tccttagaaa tcacagtaac ttttatgcag gtgtaaagag tgttctccaa
    16321 gaaaaagacc gccttggtgg gattattggt gctgttagtg agcatttgac ctttgatgtg
    16381 cattatcaaa ctgccttaga gattgcctta ggggcaagta gccagcatat catcgtagaa
    16441 gatgaagagt cggcaaccaa ggctattgac ttccttaaac ggaacagagc cggtcgtgca
    16501 accttccttc cgttgacgac tatcaaggcg cgtacgattt ctagtcagaa ccaagatgtt
    16561 atcgctgcaa gtgcgggatt tctaggcatg gcagatgagt tggtgacatt cgatacgaga
    16621 ctggaagcta ttttcaagaa cttgctagct acgacagcga tttttgatac cgttgagcat
    16681 gcgcgtgcag cagcgcgcaa agttcgttat caggttcgta tggtgacttt ggacggtaca
    16741 gagttgcgca caggtggttc ttacgcaggt ggagccaatc gtcagaataa cagtattttc
    16801 atcaagccag aactggagca attacaaaaa gaaattgctg aagaagaagc aagtttgcgt
    16861 tcagatgaag tgagtttgaa gaacttgcaa gatgagctag ctagattgac agaaagatta
    16921 gaagccatca aatctcaggg agagcaggct cgtattcagg agcaaggctt gtccctcgcc
    16981 tatcagcaga ccagtcagca agttgaagag ctagaaactc tttggaaact ccaagaagag
    17041 gaattaaatc gtctttctga gggagaatgg caagcggata aggaaaaatg ccaagagcgc
    17101 cttactacaa tcactagtga aaagaataat ctggaagctg agattgaaga gattaagtct
    17161 aataaaaacg ccatccaaga acgttatcaa aacttgcagg aagagctagc tcaagctcgt
    17221 ctacttaaga cagaactgca agggcaaaaa cgttatgaag tgactgatat tgaacgctta
    17281 ggtaaggaac tagataatct tgatattgag caagaagaaa ttcagcgcct tcttcaagaa
    17341 aaggttgaca atcttgagaa ggttgataca gaattgctca gtcaacaggc ggaagaatcc
    17401 aaaactcaga aaacgaacct ccaacaaggt ttgattcgca aacagtttga gttggatgat
    17461 atagaaggtc agctggatga tattgctagt catttggatc aggctcgcca gcagaatgag
    17521 gagtggattc gcaagcaaac acgtgctgaa gccaagaaag aaaaggtcag cgagcgcttg
    17581 cgccatctac aaagtcaatt aacagaccag taccagatta gctatactga agcactagaa
    17641 aaagcgcatg agttggacaa tctcaatctg gcagagcaag aggtgcagga tttagagaag
    17701 gctattcgct cactgggtcc tgtcaacttg gatgctattg accagtacga agaagttcac
    17761 agccgtctgg atttcctcaa tagccagcga gatgacattt tgtcagcgaa aaatctgctt
    17821 cttgagacta ttacagagat gaatgatgag gtcaaggaac gctttaaatc aacctttgaa
    17881 gctatccgtg agtcctttaa agtgaccttc aagcagatgt ttggcggagg tcaggcagac
    17941 ttgatattga ctgagggcga ccttttaaca gctggtgtgg agatttctgt tcaacctcca
    18001 ggtaagaaaa tccagtcgct taacctcatg agtggtggtg aaaaagctct atcggctctt
    18061 gccttgcttt tctccattat tcgtgtcaag accattcctt ttgtcatctt ggatgaggtg
    18121 gaagctgcgc tggatgaagc caatgttaaa cgttttgggg attacctcaa ccgctttgac
    18181 aaggacagcc agtttatcgt tgtaacccac cgtaagggaa ccatggcagc ggctgattcc
    18241 atctatggag tgaccatgca agaatcgggt gtttcaaaga ttgtttcagt taagttaaaa
    18301 gatttagaaa gtattgaagg atgacaatta aactagtagc aacggatatg gacggaacct
    18361 tcctagatgg gaatggacgc tttgatatgg atcgtctcaa gtctctcttg gcttcctaca
    18421 aggaaaaagg gatttacttt gcggtggctt cgggtcgggg atttctgtct ctggaaaaat
    18481 tatttgctgg tgttcgtgat gacattattt tcatcgcgga aaatggcagt ttggtagagt
    18541 atcaaggtca ggacttgtat gaagcgacta tgtctcgtga cttttatctg gcaacttttg
    18601 aaaagctgaa aacgtcacct tatgtagata tcaataaact gctcttgacg ggtaagaagg
    18661 gttcatatgt tctagatacg gttgatgaga cctatttgaa agtgagtcag cattataatg
    18721 aaaatatcca aaaagtagcg agtttggaag atatcacaga tgacattttc aaatttacaa
    18781 ccaacttcac agaagaaacg ctagaagctg gtgaagcttg ggttaatgaa catgtccctg
    18841 gtgttaaggc catgacaact ggctttgaat ctattgatat tgttctggac tatgtcgata
    18901 agggtgtagc tattgttgaa ttagctaaaa aacttggtat cacaatggat caggtcatgg
    18961 cttttggaga caatcttaat gacttacata tgatgcaggt tgtgggacat cctgtagctc
    19021 ctgaaaatgc acgacctgaa attttagaat tagcaaagac tgtgattggt caccataagg
    19081 aacggtcggt tatagcttat atggagggct tataatggca gatataaaat tgattgcatt
    19141 ggacttggac gggaccttgc tgactactga taaaaggctg acggatcgta ccaaggaaac
    19201 cttgaaagct gcgcgtgatc gtggtatcaa ggtcgtattg acaactggtc gtcccttaaa
    19261 agccatggat ttctttctcc atgagttagg gactgacggt caggaagatg agtataccat
    19321 tacttttaat ggtggattag ttcagaaaaa tacaggagaa atccttgata aaacagtctt
    19381 ttcatatgat gatgtggcac gtttgtatga agaaacagag aaattatcac tgcctcttga
    19441 tgccatctca gaaggaacag tttatcaaat ccaatcggac caagaaagtc tttatgccaa
    19501 attcaatcca gctttgacct ttgttccagt ggactttgaa gacttatcta gtcaaatgac
    19561 ctacaacaaa tgcgtgactg cctttgctca agaacccttg gatgcagcca ttcagaagat
    19621 ttctccagaa ttgtttgacc aatatgaaat ctttaaatca cgtgaaatgt tgctagaatg
    19681 gtcaccaaag aatgttcata aagcaacagg tttggcaaaa ctaatcagcc atcttggaat
    19741 cgaccaaagt caagtgatgg cttgtggtga cgaggccaat gacctctcta tgattgaatg
    19801 ggcaggtctt ggtgttgcta tgcaaaacgc tgttcctgaa gtaaaggtag ccgcaaatgt
    19861 agtgacgccg atgaccaacg atgaggaagc tgtcgcctgg gctatcgaag aatatgtgct
    19921 aaaggagaac taagatatgg gattgtttga ccgtctattc ggaaaaaaag aagaacctaa
    19981 aatcgaagaa gttgtgaaag aagctctgga aaatcttgat ttgtctgaag atgttgatcc
    20041 taccttcaca gaagttgagg aagtttctca ggaagaagca gaggttgaaa ttgttgaaca
    20101 agctgtgttc caagaagagg aaatccaaga cacagttgaa gaaagtctgg atttagagcc
    20161 agttgtagaa gtttctcaaa aagaagtcga agaatttcca cactcagaag aagggaatac
    20221 tgagttttta gagactgtag aagaaaataa ttctgaaatt cttgaagcag aaaggcctca
    20281 aacagaagaa actgttcagg aaaagtatga ccgcagtctt aagaaaactc gcacaggttt
    20341 cggtgcccgc ttgaatgcct tctttgctaa cttccgctct gttgacgaag aatttttcga
    20401 ggaactggaa gaactgttga ttatgagtga tgttggtgtc caagtcgctt ctaacttaac
    20461 ggaggaacta cgttacgaag ccaagcttga aaatgccaag aaacctgatg cacttcgtcg
    20521 tgtcatcatt gagaaattgg ttgagcttta tgaaaaggat ggtagctacg atgaaagcat
    20581 ccacttccaa gataacttga cagttatgct ctttgttggt gtgaatggtg ttgggaaaac
    20641 aacttctatc ggaaaactag cccaccgcta caaacaagct ggtaagaagg tcatgctggt
    20701 tgcagcagat accttccgtg cgggtgcagt agctcagcta gctgaatggg gccgacgagt
    20761 agatgttcca gtagtaactg gacctgaaaa agctgatcca gccagcgtgg tctttgatgg
    20821 tatggaacgt gccgtggctg aaggtatcga tattctcatg attgatactg ctggtcgtct
    20881 gcaaaataag gataacctta tggctgagtt ggaaaagatt ggtcgtatta tcaaacgtgt
    20941 tgtgccagaa gcaccacatg aaaccttctt ggcacttgat gcatcaacag gtcaaaatgc
    21001 cctagtacag gccaaagaat tttcgaaaat cacaccttta acgggaattg ttttgactaa
    21061 gattgatgga actgctcgag gaggtgtggt tctagccatt cgtgaagaac tcaatattcc
    21121 tgtaaaattg attggttttg gtgaaaaaat cgatgatatt ggagagttta actcagaaaa
    21181 ctttatgaaa ggtctcttgg aaggtttaat ctaatcagaa gcaaaaatcc tgcaaggcat
    21241 aaacttgcag gaaatttttt tattctaagc gaccatcttg acgataggtg atatctggtt
    21301 gccaagtcca tttggcaccg aatttttcaa gtaggtcaaa gctggcttga ggtcccatgc
    21361 ttccagcttt atagtcatga agtggggcac cattttcagc ccagagcttt tcaatacggt
    21421 caatcaactt ccatgacgca caaacttcat cccagtggct aaagttagtt gagttgttat
    21481 ttaggacatc ataaatcaat ttttcgtatg gttctggaga agcaccagtt gcagtcgcat
    21541 ctgtacggta atcaagtgag ttaggagcca agttaaattc ttctcctact tgcttcccat
    21601 ttaggctaag agagaagcct tctgttggtt gaatatagat ggtcaaaata tttggagcaa
    21661 gtggttctcc aaagatagaa tccatttgtt taaagacgat gttgacatgg gttccttttt
    21721 cagtcagtcg tttacctgta cggaaaaaga aaggaacact acggaatcga tcgctgtcta
    21781 caaagaaggc accagatgta aaggtttcag ttgttgattc tggattcaca tttggctcgc
    21841 tacgataaga gatgtatttc atgccatcaa tcttaccaga gcggtattgc ccacgtataa
    21901 agtgttcttt gagttcttca tcagttggat gatagaggtt tttaaagacc ttaatctttt
    21961 cagcacgaat ctcgtctttt gtgaagcttg ctggtttgtc catggcgagg agcgaaagaa
    22021 gttgtagagt gtggttttgg accatgtcac ggagggcacc ggattggtca tagtagccac
    22081 cacgttcttc tacacccaag cgctccgcaa aggtaatttg aacattgtcg ataaaatcct
    22141 tgttccaaac gttttcaaaa atcaagtttg caaagcgaac tgcaaagatg ctttggatca
    22201 tttccttacc aagataatgg tcgatacgga aaatttgttc ttcgtcaaat gttgctagga
    22261 gttcgtcatt caacttgctt gcagttgcgt aatctgtacc aaatggtttt tcaacgatca
    22321 agcgctcaaa acctttgcca tcgacaatgt tttcagattt gaggtgtttg gcaatggttc
    22381 caaagaactg aggtgccata gacaagaaga agagcttatt gtgttcagct tggtattttt
    22441 cattaagctc agcttgtaat tgacgcaaag caatataatg ttccgaatca ttgacatcat
    22501 ggctttgata gtagaagtgg ctagcaaatt cttgggcttg ctcggtacta tctgccaaat
    22561 caaggatgga ctcgacaact acagattcaa aatattcctt actccaaggt ctacgggcag
    22621 ttccaataac ggcaaagtgc ttggaaagat tgccggattt atatagtcta aaaagggaag
    22681 ggtagagctt gcgtttagcc aggtctccac tcgcaccgaa aattgtaaca ataaccttag
    22741 atgacatcta gctacctaat ttctattttt attcctagtc ttgctaggta tgaggaaacc
    22801 tcatttcata aacttaattc taacataatt ttccgaaaaa tcaaaaattc caatacgagg
    22861 tagaaaaact gcaaggaaat ccttacagtt tgagtttaga cgtttaagac cttatctaag
    22921 aactctttca gacgagggtg ttgtgggtta tcaaagattt ggtcaggtgt tccgtcttca
    22981 aggaactcgc catctgcagt aaagataacg cggttggcaa cctgacgagc aaatcccatc
    23041 tcatgggtta cgataatcat ggtcatgcct tgctcagcca attccttcat aacgttaagt
    23101 acgtctccaa ccatctcagg gtcaagggca gaagttggtt catcgaagag catgatgtct
    23161 ggattcattg ctaggccacg agctatggcc acacgttgtt tttgaccacc tgataggcta
    23221 tctggattgg cattagcttt atctgctagt ccaacctttt caagcaactc cattcccaat
    23281 ttctcagctt cttccttagt catcaacttg tgctcaatag gagcaaaggt gatgttgtcc
    23341 aatacagaca tatgagggaa gaggttgaag tgttggaata ccatgccgat attttcacgg
    23401 acgtggtcaa cattggttgt tttttcagtt aaatcatagc cgttcacagt gatgtgaccg
    23461 ctagtgactt cttctaaaag attgaggcta cggaggaaag ttgacttacc agaacctgaa
    23521 ggaccgatga tacaaacaac atctccttca tagaacttag tcgtaattcc ttttaggact
    23581 tcattttttc catagtgctt gtgtaaatca tttacatcaa tttttaattt tgccattaac
    23641 gaatcctctt ttctaagcgt ttcgctagtc tagtcaaaag tgtgataatt acaagataga
    23701 agatagcaag gattgcatac atcttgaaac tttggtagtt acgagcaatg ataatcttac
    23761 cagtttggaa gagttcaacc aaaccgatag cagatacgat agttgtatct ttaagagcga
    23821 taacgaattg gttgacaaag tttggcaaca tcaatttagt tgcttgtggc aagataatct
    23881 tacgcatggt ttttccataa gagataccca agcttcggct ggcttccatt tggccaactg
    23941 gaacggcctg aataccacca cgaacgattt cagcgatata agcagccgca ttgagtgaga
    24001 gggcaatggt tccagctaca aagtcgttaa ttgggctttg ttggcctgtg atagactcga
    24061 tgaagtttgg aattccccag aagatgaagg ctgcaagaat catcaatgga ataccacgaa
    24121 taacgtcaac gaaaatctca gagatgacgc gaagagattt gtatgggcta acgctaaaca
    24181 taccgaagat aattccgatg acaatggcaa tagcaaatga gataagagct agagcaagag
    24241 tgataccaag accgctaagg agttgtttgt agttgttttg aagcaagccc cagagcgttg
    24301 tttcgtcaac agtacttgtt gaagcagttg aagattcgct agctaggtat ttgtcaagaa
    24361 tcttttggaa ttcaccgttt gctttaaggt ttgcaagtcc gttgttgaac atttcaatca
    24421 gttctggatt tgctcctttt ttaacggcaa aggctgtttc accgattgga gttccagaga
    24481 ttggagtttt caatttttga ccttggctga tagaatattt gagaacaggt tcatcatcca
    24541 taacggcatc aatggcacca gtgtttaaac tgtcatacat tgaagaacca tcagcaaagg
    24601 ttttgatttt gtagccgtat ttgctttgat tttctgttag gaaggtttga gaagcagttc
    24661 cgtttttaac accgactgtc tttcctttta gatcttcata agaagcaata ttgcttgatt
    24721 ctttgacacc aagaatggta ttagcagtgt agtatgattc tgagaagtca aaagttgcct
    24781 tacgagcatc tgtgacagac ataccagcga tgataccatc ggcttgacca gcttggacag
    24841 cactgatagc agcatcaaaa ccagggttgg tgatttcaat ttcaaaacct tggtctttag
    24901 cgattgcctt aatcaattcc atatcaatac cagtgtattg gttgcttgaa ttttggaaaa
    24961 caaaaggtgc aaaagaagaa tcgctggcaa tgatatattt agccttaaca ggaatagctt
    25021 ttaatcctgc gagagtagtt gtagttggca ctgctgaaga tgatgaagca gtccatttct
    25081 tgataatttt atcaagacta ccatcttttt tcatttcaga caaggcttgg ttaaattcag
    25141 taactaggtg ctcgtattta cttccttttt tcacaccgaa agcaaaactt cctacagctt
    25201 caccatccat ttcaatatgg aggtcttgac cttggttaat ggcatattcg ataacaggtt
    25261 tgtcatccat catggcatcg atggcaccag cactcaagct gttgttcatt aaatcaccag
    25321 tgtcaaatgt tttaatagta aagccgtatt tatctttgat tgtttcaagg aaacgttgag
    25381 cggcagttcc gtttttaaca ccaacggttt tgccagttaa ttggtcgtac ttgctaattt
    25441 tgtgtgactt tgtagtagca atgacaactt ttgtatcata gtaagtatca gacatggtga
    25501 agactttttc acgttcttta gtctttgtca tccctgccat gatagcgtcg gcttgcccag
    25561 cttgaaccgc attgactgct gcgtcaaatc caggatagga catctgaatg ttccagcctt
    25621 taatctcagc gactttgtta ataatgtcaa catcaattcc tttataagtt tgatctgaat
    25681 ctttaaactc aaaaggtgca taggcggtat cagaaacaat cttaatcgtt tctgctttgg
    25741 caatacctaa tgagaaaatt gggaataaaa ttagcaaaaa tgctagaaat tttttcttca
    25801 tttttagtct ccttttccga a
//
LOCUS       DAVLMQ010000024        25238 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000024 DAVLMQ010000000
VERSION     DAVLMQ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25238)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25238)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25238
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.024"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(137..508)
                     /locus_tag="VXF95_001219"
     CDS             complement(137..508)
                     /locus_tag="VXF95_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0218 family bacteriocin-like peptide"
                     /protein_id="HEV1081770.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAIYIPRWAITGAITGAAYAAL
                     AAAGGGGLQLVLASYGLRSALVAGIVKGLGVLGIHIGNAFANTVIRSIASAGIGAGAD
                     WIFTNIIDGWDGRRDNQLRIG"
     gene            1145..2008
                     /locus_tag="VXF95_001220"
     CDS             1145..2008
                     /locus_tag="VXF95_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001268160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1081771.1"
                     /translation="MRYDFGKVYKEIRESKGLTQEEVCGGVLSRTSLSKIESGKTTPK
                     YENMEFLLRQINMSFEEFEYICQLYQPSQRTEIMQTYLNMRSIIGTSDLVNLFQKCQD
                     YLKIHHDLPIEEIRDMLEVVIYIRQHGAGELSDHAEQVVKKLWRKIEKQDTWYESDLK
                     ILNTILFSFPIEYLHLITGKILQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMC
                     KQICYTLLEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKK
                     EVEIYYQAKER"
     gene            complement(2194..2664)
                     /locus_tag="VXF95_001221"
                     /pseudo
     CDS             complement(2194..2664)
                     /locus_tag="VXF95_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
     gene            complement(2630..3436)
                     /locus_tag="VXF95_001222"
     CDS             complement(2630..3436)
                     /locus_tag="VXF95_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HEV1081772.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSTPYYTAKNKLIVKKSDLATYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVAKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            complement(3643..4284)
                     /locus_tag="VXF95_001223"
     CDS             complement(3643..4284)
                     /locus_tag="VXF95_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081773.1"
                     /translation="MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK"
     gene            complement(4281..6389)
                     /locus_tag="VXF95_001224"
     CDS             complement(4281..6389)
                     /locus_tag="VXF95_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1081774.1"
                     /translation="MKKISNFCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATVLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLIFNYVMKIGTTILLTAL
                     LIGVGRSLEQENKELAYQQQWVSQGNYLTLETFKLNDNLWQEELAGSGKSTDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVTTFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     GLASRMEKRSLVELLKGGIL"
     gene            complement(6441..6728)
                     /locus_tag="VXF95_001225"
     CDS             complement(6441..6728)
                     /locus_tag="VXF95_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1081775.1"
                     /translation="MRKLVKIGVASLMVCGILATTNALAVWVEGGQWNYGVGWTGTFG
                     YSDYLHSTRYHTATVRHGGRTSKDYAKPEAWARASLTKIPPTVMEYFYGFE"
     gene            7159..7479
                     /locus_tag="VXF95_001226"
     CDS             7159..7479
                     /locus_tag="VXF95_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1081776.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDNAKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            complement(7532..8104)
                     /locus_tag="VXF95_001227"
     CDS             complement(7532..8104)
                     /locus_tag="VXF95_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1081777.1"
                     /translation="MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            8346..9017
                     /gene="sdaAB"
                     /locus_tag="VXF95_001228"
     CDS             8346..9017
                     /gene="sdaAB"
                     /locus_tag="VXF95_001228"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HEV1081778.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            9026..9898
                     /gene="sdaAA"
                     /locus_tag="VXF95_001229"
     CDS             9026..9898
                     /gene="sdaAA"
                     /locus_tag="VXF95_001229"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HEV1081779.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIENGKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            9920..10552
                     /locus_tag="VXF95_001230"
     CDS             9920..10552
                     /locus_tag="VXF95_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1081780.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKDTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAITWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            10602..10679
                     /locus_tag="VXF95_001231"
                     /pseudo
     CDS             10602..10679
                     /locus_tag="VXF95_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(10855..12705)
                     /locus_tag="VXF95_001232"
     CDS             complement(10855..12705)
                     /locus_tag="VXF95_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HEV1081781.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(12747..13904)
                     /locus_tag="VXF95_001233"
     CDS             complement(12747..13904)
                     /locus_tag="VXF95_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1081782.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTESFVMNNVAIIQQGEFVCGGPRP
                     TIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREYGYKIRYSPSILSYQYIRPTFKKMLHQKYLNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGF
                     LIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKRTIIYLDKISQINKNML"
     gene            13962..15128
                     /locus_tag="VXF95_001234"
     CDS             13962..15128
                     /locus_tag="VXF95_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HEV1081783.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFY
                     TVMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVS
                     LAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGL
                     SQTGGYILAAFGPTLFGYSFDLFHSWVPSVAALLLIDILMTVALFTVDRADKIL"
     gene            15267..15593
                     /locus_tag="VXF95_001235"
     CDS             15267..15593
                     /locus_tag="VXF95_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HEV1081784.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            15580..16173
                     /locus_tag="VXF95_001236"
     CDS             15580..16173
                     /locus_tag="VXF95_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HEV1081785.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTILAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA"
     gene            16166..17077
                     /locus_tag="VXF95_001237"
     CDS             16166..17077
                     /locus_tag="VXF95_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HEV1081786.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVY
                     DSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTDNHFHAEN
                     IQVHGKVELTAKDYLRIILDQKENQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            17139..18203
                     /locus_tag="VXF95_001238"
     CDS             17139..18203
                     /locus_tag="VXF95_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081787.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGK
                     NTQVEEEVSQAEVELESQQEEKIETPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(18274..19120)
                     /locus_tag="VXF95_001239"
                     /pseudo
     CDS             complement(18274..19120)
                     /locus_tag="VXF95_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
     gene            complement(19395..20381)
                     /locus_tag="VXF95_001240"
     CDS             complement(19395..20381)
                     /locus_tag="VXF95_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HEV1081788.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            complement(20653..22128)
                     /locus_tag="VXF95_001241"
     CDS             complement(20653..22128)
                     /locus_tag="VXF95_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HEV1081789.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            complement(22386..23309)
                     /locus_tag="VXF95_001242"
     CDS             complement(22386..23309)
                     /locus_tag="VXF95_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1081790.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            complement(23323..24252)
                     /locus_tag="VXF95_001243"
     CDS             complement(23323..24252)
                     /locus_tag="VXF95_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1081791.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            complement(24571..24792)
                     /locus_tag="VXF95_001244"
     CDS             complement(24571..24792)
                     /locus_tag="VXF95_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081792.1"
                     /translation="MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQEELQKAVLF
                     LADEKGSEHTEAELIDNLKEVIAKLKANA"
     gene            complement(24746..25006)
                     /locus_tag="VXF95_001245"
     CDS             complement(24746..25006)
                     /locus_tag="VXF95_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081793.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
BASE COUNT         7683 a         5446 c         4492 g         7617 t
ORIGIN      
        1 gtaattccaa ataaaatgag aaatcagcaa tgatagaaaa ataacaatat caattttcct
       61 gttgttgaca tactctgtaa ttttatgata cagtaatgca acaataactg aaattaaaac
      121 aatcaacata agattattaa cctattctca attgattatc acgtcgccca tcccagccat
      181 caataatatt ggtaaaaatc caatcagctc cagcaccaat tccagcagat gcaatacttc
      241 taataacagt atttgcaaaa gcatttccaa tatgaattcc taatactcct aaacctttaa
      301 caatcccagc taccagtgcg gagcgtaatc cataagatgc aagaactagt tgaaggcctc
      361 cacctcctgc tgctgctaat gctgcatatg ctgcaccagt aatggctcct gtaattgccc
      421 acctgggtat atatatagcc cccccatcaa ggtacatcat ctcttcttca tcaatcacaa
      481 cataattatt tggtaataca agttccattt attttctcct tttttattaa gcatgcttag
      541 gatggtttcc taacaagtga tcgcaggctt tgtttagtta cctaaattag acttccttcc
      601 tttatcttat tttaaatatt taaaaccagt tactgcttga agcttaacag tttacttaat
      661 tcaaataaca gctaatcact gattccctga ttttatcaaa tatactaata acaacaattg
      721 tgatacgatc atcattataa gaacaacatt taacgaatca aagtttttcc gagataataa
      781 taaagcaaca gcaagcagta ttattactaa agattgaata actactatta ctcttaacat
      841 tttatcctcc actaacaact caagctccct tacattatat cgaccagccc catggaaaga
      901 ttatagctag actaatcaat gatataatac atactagaat acaaaatatt tttttattca
      961 tactttttct cctatcttta ttttctacct acatagtacc tcttattaag ctcatttcaa
     1021 aattacgtta acttttttca caaatttatt tcgactttct tttttacttt ttacattgct
     1081 atgatacaat atttttaaca agattttatt atttgttaac ttttttcaca gaaaggagaa
     1141 aatcatgcgt tatgatttcg gaaaggtcta taaagaaata cgtgagtcaa aggggctgac
     1201 ccaagaagag gtctgtgggg gtgttctctc aagaaccagc ttatcaaaaa tcgaaagtgg
     1261 caagacaacc ccaaaatatg aaaatatgga atttcttctc cgtcaaatca atatgagttt
     1321 tgaagagttt gaatatatct gtcaacttta tcaaccaagt caacgcacag agattatgca
     1381 aacctatctc aatatgcgtt ccattatcgg gaccagcgat cttgtcaatt tatttcaaaa
     1441 atgccaagac tacctcaaga tccaccacga tctccctata gaagaaatca gagatatgct
     1501 tgaagttgtc atttatatcc gtcaacacgg ggcaggggaa ctatcagatc acgcagaaca
     1561 ggttgtcaaa aaactttgga gaaaaattga aaaacaagat acatggtatg agagtgatct
     1621 aaaaatcctc aataccattc ttttcagttt tcccattgaa tacctccatc tcatcactgg
     1681 aaaaatattg caacgcctag aagtctataa aaactatcaa catttatatg acttgcgaat
     1741 agcaatcctg ctcaaccttt ccacactcta tctatacaat caagataaaa acatgtgtaa
     1801 gcaaatctgc tacactttac tggaggacgc caagaataag aaaagctacg ataggctggc
     1861 tatctgctat gtccgcattg ggatttgtac agacgattct aaacttatcc aaaaaggttt
     1921 ctcactccta gagctgaccg aggaaacttc tatgctgtct catctcaaaa aagaagtaga
     1981 gatctattac caagcgaagg aaagataaaa aagccgaggg agctcctcga ccttttcata
     2041 gaatcgccga acgatttaac gagaaagtat gacttttacg tttatcccaa ctcaattatg
     2101 acattttttt caaaagtcaa tatatctcac tttttcaacg acaagaaaga ggctgccaat
     2161 cgaccaacct cttattctga acccatcact ccatcacttt ttagcttcat tcgctttctt
     2221 agcgactgca atctggtatt cgacttggtc aaacccctta ccggtacaac catgagcaat
     2281 tgtagtcgct cctatctgat gcgctatttc aaccaatttt ttagaaatca gagggcggct
     2341 caaggcagat accaagggat acttttgttc ataataggca tgtgactaat gagccactag
     2401 cacataatct gtagcaaatt cgtccttaac atcaatgaca taagattcta ctgcccaaac
     2461 cttaagagcc ttatcatgga tgaaatctaa gtctttccct tcacccacat ccatacaaac
     2521 tgaaacaaca tcatagtctt tctttaacca ggtaatagca actgatgtgt ccaaaccgcc
     2581 agaataggcc aaaattactt tttctttact catgttcttt tccttctttc tatttttcaa
     2641 tggatgcttt aaaggcatcc tcaatgagtt tgtctaattc cccagactcc ttcaactttt
     2701 gaatggtttt atcgactgcc tctttcaatt ccttgctatc ttttttcatg gctaccgcat
     2761 aggaatcatc ttgctctttt tcaaaattga ggtctgcgat tgctaaatca ggattatttt
     2821 ccacaaatcc cttggcaacg ggttcttcaa aaataacggc atccacttgc cctgatttta
     2881 aatctgtgat taaattccca tttttaggca gagatacgag ggaagaattt tgtagcaaat
     2941 ctttcgccat cgtctcttga atcgaacctt tctgcgctcc gacctttttc tgcgccaaat
     3001 cgttgacaga ctgataagtg gctaaatcag attttttgac aatgagttta ttttttgcag
     3061 tatagtaggg agttgaaaaa tcaaacacct tgctccgttc atctgtctta gaaacacctg
     3121 atatggcaag gtcagctttt cctgattgaa cgctagccag tacattgtca aaactcatag
     3181 gagatagttc caattcgaca cctagttctg ttgcgatagc cttggctaat tcgatatctg
     3241 aacccacaat ctgatttttc ccatcaacca ctttttgata ttcaaatgga gcaaaatctg
     3301 gattgagggc tacaaccaat tttcctttgg acttgatggc ttcaattcca gccgattgat
     3361 tgttactaca agcaaatagt agggggagca tcactaaacc aaacatcgtc atcaacacct
     3421 tcttcatctt attcataaca aagcctcctt tatgtttatt cttttttatt gtataaacaa
     3481 tactcctata ctcatccttt gtcaagccta aattgaaaaa attttcaatt tgaaacaaaa
     3541 aaaacctaga aatactacat aaaatgtcat tcctaggcgt atttatgcta tttttctctg
     3601 gaaaacatga gtattcagcc agtcaaaagg agctgaatga actcattttc cctcgcccaa
     3661 ttcaatgaca cgatgacatt gttgggctac ataagcatcg tgggtcacaa taatgactgt
     3721 tttcccttct cgattcatct ctaagagaaa cttcaagacc aaatctctat tttcaggatc
     3781 cagcgaacct gtaggttcat cggctaaaat cagctggctg ggttttaaga tggctctagc
     3841 aactgcaatt cgttgttgtt cgcccccaga caactcggag accctttgat gcaaagtagc
     3901 tgacaaacct actctctcta aaatctcttc cacctttttg agcttgtctt tcttaggcaa
     3961 tttcacatat ttcagcgcca gcatgagatt gtactcgacc gtttcatcat caatcagggc
     4021 aaaattttga aacagataag agatatgttc acggattatt gtttgcgact tagcagaatt
     4081 aaccgctaga tttgtctgac caaaaatctc ataccgtccg ctataatcac catctatcaa
     4141 acccaataaa tttaacaagg tcgacttccc actaccactc ttaccaacaa tagctaccaa
     4201 atccccctga tcaatcctga gagataagtt atccaaaatc acttttcccc caatggtttt
     4261 ggtaatattt ttcaactcaa tcataagatg ccccctttca ataactctac tagacttctt
     4321 ttctccatcc tagaagctaa gcctagcaca aatagtatat ccagacatgt aaaacctgca
     4381 aacagtagaa gtggtaagaa cgcatgggca aagaaaatca agactagaag agggaaacta
     4441 tagcccagca agagcagaac gaggagagga cggtagcgat cgaccagttt ccaccccata
     4501 aacttcttgg taatgatatc cctgcgcttc aataagaaag ttgttactag taagaagtag
     4561 gaaatcatca tgctaaggag accaaacaaa gcaaagagta ggttaaaatt ccgaacagca
     4621 tctctataag aatccacttt ctcttgttga atggcttgaa tagatgaaaa ttttaaataa
     4681 tttccatctg acaatttctc aactaactct gtaatctctt tttgatgttg aaccgtattt
     4741 tcaattttaa tcggattatt taagccagtt gttgacaggg aggctttctc atcccacatc
     4801 atatcagaat cattgaccaa gctaataatt ggattggaga gattttcctt tcgcttatca
     4861 ctatatggga aaaatgacca atctccttca taataggcaa tctcgacatc catctcctct
     4921 atcgttcgtt tttgctgctc ttcatacttc atcgaatgaa aggcaattaa cttccccaag
     4981 agctgatttt tatcttcttc acctttcgta cttgctggca tcaaaataac ttttttaata
     5041 ccggtatctg gtagcttgaa tcccttgctc tttagaaaat tgcgattggc atagtaaaca
     5101 tccaccgtat ctgttaactg atattgctga atctgttctg attggacaaa attttttaca
     5161 ggaagactgc tactctgcac atagcccgcc tgcgtttttt ctaccaaatc ctgataaaat
     5221 cgatagaaat aatctgtaga tttccctgac cctgctagct cttcttgcca cagattatca
     5281 ttgagtttga aggtttctaa ggtcaggtaa ttaccttgac ttacccactg ttgctgataa
     5341 gcaagttctt tgttttcttg ttctaaactt ctgcccaccc caatcagtaa ggccgtcagt
     5401 aaaatagttg tccctatttt catcacataa ttgaagataa gaccaaattt gaaagatgaa
     5461 aaacctttca gcagagagct gattgtcatt ttttggatta agaggtaagt caaccaactg
     5521 ataaagagat aaagctgcaa cagcaaaaaa tgagacaacc acagcatagg aaacaaatct
     5581 tttggcttat aatcaagcaa gaaaaacacg cctagattga tcacaagagc cccacctagg
     5641 aggaggtaaa ggttgccttt tacaacatca gctaaaacag ccctatcttg aaaaccaagt
     5701 aatttttgta ccccaactct tttcatctcc atcatcggtt gatatactgt cactaacaca
     5761 agaagcaaaa tagccaagac aaaaacaatg gcagataaaa gcaaatctcg atttatgact
     5821 tccactgcac ttttgtaggt cggctctagc acggtagcct ggtctatctt gaaaaaatcg
     5881 ctccatttct gtacaatcct atccttgtcc atctcttgtg tagaagttat cgtatagcga
     5941 ccatttaaac tacgagatgt atccttgata taggtttgaa aagtcataag ctgaataggt
     6001 ttggctttta gaaaggtcgg aatcgtacca agtttattgg aaatttcttt attactatag
     6061 actccttcac catctgtggt aaaatcaaga gaagaaatcc caaactcttg gtaggggaag
     6121 gtatctttat caaaaacacc agacttgacc acctcatcac cactgtctgt tttgatgatg
     6181 gagactttat actcctttga tacatcctca aaaaatcgaa gaacagacgc tgcaggttcg
     6241 ttaatatctt tcaaatacaa atccaaagaa tctacagtct ttcccatttc ttgaatccga
     6301 accacttctc gtgtatagtt tacattaaaa acaaaaaaag tggtacacag aagcaggagt
     6361 aacatacaga aattactgat ttttttcata aaagtgcctc cactacagtt ttccctctcc
     6421 aaataggaga gggaagaatt ttactcaaat ccatagaaat attccattac tgttggcgga
     6481 atcttggtga gggaagctct agcccatgcc tcaggttttg cataatcctt agaggttcta
     6541 cccccatgtc taacagttgc tgtatgatat cgagtagaat gtaagtaatc agaatatcca
     6601 aaagttcctg tccaacctac tccatagttc cattgaccac cctcaaccca tactgctaaa
     6661 gcatttgtag tagcaagtat accacatacc attaaagatg caacaccaat tttaactaat
     6721 tttctcatga tttatttctc ctattatcga gagctgttcc gtaaaaacag ctatagtaat
     6781 ttatcaacaa gtatcgtagt ccattggact caccttcctt ctatctcatt tcatttttta
     6841 acaacgaact tactcttaac cgggagaatg gtgcgcttct gtatcaggtc cttgaacaac
     6901 cagagtagta ttaagcacac tctaactatt actcaagaat cagtccaata aacaatatgg
     6961 atagcgcttt caaattttta aactcctatc ccgtcctttt atctatataa taagcataag
     7021 cgaaaatata ataactgtca agtatctgaa gtgaatttta taaaaaaatt acaagccaaa
     7081 tttgtaaagt ttacactaag ccgctagggc aatcgtctat cagaatgtcc gtttatttgt
     7141 caataatccg agaaaatctt gcaacgctta gaagtctata aaaactatca acatttatat
     7201 gacttgcgaa tagcaatcct gctaaacctt tccacactct atctatacaa tcaagataaa
     7261 aacatgtgta agcaaatctg ctacacttta ctggaggacg ccaagaataa gaaaagctac
     7321 gataggcttg ctatctgcta tgtccgtatt gggatttgta cagataatgc taaacttatc
     7381 caaaaaggtt tctcacttct ggagctgacc gaggaaactt ctatgctgtc tcatctcaaa
     7441 aaagaagtag agacccatta tcaaccaaag aaattataaa aaaagtcgag ggagctcctc
     7501 gaccttttac atattatttg ttcgttagtt cttaatacca gccattgtta agccagaagt
     7561 ttttagcagc agtccatgaa ccgtaacgtc ctgcaacgta ggcatctgct acacgttctt
     7621 ggttttcagc tgagtagtca ccgttcaggt atgaatctgt taattggtaa cgtccgatat
     7681 aacgtccatt tgtagctgta tagctaccac ctgattcttt ttgagcgatc cattctttgg
     7741 cttctgcttc agatccgctt acagttgaaa caactgtttc acttactact ggagctgaaa
     7801 cagtttcatc ttgagcggct ggtgccgcat aagtagctgg cgctggtgtt gcaacaggcg
     7861 ctacagggcc atcgataacc aactcttgat caacataaat caaatgaatg ttatcaatgt
     7921 ggttgttttc tgccaatttt tcaactgttg tgttgtgagt ttcagcgatt tctgaaagtg
     7981 tatcaccttc tttaacagtg taagttgatg attcttgagc agatacaaat gatggagcaa
     8041 atactgcaaa caaggcagct actcctgcaa gagttgcttt aatcttttta gttattgatt
     8101 tcatattcga aaattctcct tctttctata gttctatcat accctttaaa tattaccgtt
     8161 tcttgacact tttatgtaga aatattacaa aattattttt tatttcccta aataaggtgt
     8221 tttttgtcat aaaagatact atttttatgc tatttgaggt attagaaagg ttttcatcca
     8281 caattaaagc caagcccctc attctttgat ataatagaga taagaatttt tataagggga
     8341 aactgatgaa atcacttcgt tttcaatctg tctttgatat catcggacca gttatgattg
     8401 gcccatctag tagccatacc gctggtgctg ttcgtattgg gaagattgtc tcttccattt
     8461 ttgatgatac tccgacagaa gttgaattcc aactttttaa ctcatttgcc aagacctatc
     8521 gtggtcacgg aacagaccta gcccttgttg caggtatttt aggaatggat acagatgatc
     8581 ctgaaattcc aaatagtctg gaaattgccc acaagcgtgg tatcaagatt gtctggacca
     8641 ttcagaaaga cagcaatgcc cctcacccta acaccactaa aattactgtt aaaaatgccc
     8701 acaagaccat cagcgtgact ggtatttcta tcggtggagg aaatattcag gtaaccgaac
     8761 tcaatggttt tgccgtctct ctcaatatga atacaccgac tatcatcatc gttcatcaag
     8821 atattccagg tatgattgcc cttgttacag aggcgctttc ccgctatggt atcaatatcg
     8881 cccagatgaa tgtcactcgt gaaaaagctg gtgaaaaagc cattatgatt atcgaagttg
     8941 acagtcgcaa ctgtgatgag gctatcgaag aaattcgaaa aatccctcat ctccacaatg
     9001 tcaatttctt taaataggag gaagcatgtt ttattctatc aaagaattgg tcgagcaagc
     9061 agatctagac tttcaaggaa atgtcgcaga actcatgatt acaacagagt ttgaattgac
     9121 cggtcgcgaa cgtgaagaag tcttccttct catggaacgc aatctggaag ttatgaaagc
     9181 ctctgtccaa cttggcctca atgaaaataa atctcgtagt ggcctgacag gtggagatgc
     9241 tgccaaattg gatcactaca tcgaaaacgg aaaaactctg tcagattata cgattctctc
     9301 ggctgcccga aatgccatcg cagtcaatga acacaatgcc aaaatgggct tggtctgtgc
     9361 cactccaacc gctggaagtg ctggctgtct gccatccgtt ctcactgctg ctattgaaaa
     9421 attagacctc agccacgagc aacaattgga tttcctcttt gctgctggtg cctttggact
     9481 agtcatcgca aacaatgcct ccatctcagg tgctgagggt gggtgtcaag ctgaagttgg
     9541 ttcagcctct gctatgagtg ctgccgcctt gactctggct gcaggtggaa caccttatca
     9601 ggccagtcaa gctattgcct ttgtcattaa aaatatgcta ggcctcatct gtgaccctgt
     9661 tgcaggtttg gtcgaagttc cctgtgtcaa acgtaatgcc atgggagcta gctttgcttt
     9721 catcgcagca gacatggcct tggcaggtat cgaatctaaa atccctgtgg atgaagtgat
     9781 cgatgccatg taccaagtag gagcaagcat gccaactgcc tttcgtgaaa cagctgaagg
     9841 tggactcgct accaccccta ctggtcgtcg cctccaaaaa gaaattttcg gagaataagc
     9901 ttatcaaata ggagaaacca tgacctctat cacagcgatt tttttcgatt tggatggaac
     9961 cctcgttgat agttctatcg ggattcacaa tgcctttacc tataccttta aagagctggg
    10021 ggtgcctagc cctgatgcca aaactattcg tggttttatg ggaccacctc tcgaaagtag
    10081 ttttgcgacc tgcctgtcca aagaccaaat ttctgaagcc gtgcagatat atcgttctta
    10141 ctataaggca aaaggcatct atgaagctca actctttcct cagattatag acttgcttga
    10201 ggagttatcg agcagttatc cactctacat caccacgaca aaggatacat ctactgctca
    10261 agacatggca aaaaacttgg aaatccatca tttctttgat ggcatttatg gttctagccc
    10321 tgaagcaccc cataaggcag atgtcattca ccaagccttg cagacacatc aactagcacc
    10381 agaacaagcc atcatcatcg gagataccaa gtttgatatg ctgggagctc gagaaacagg
    10441 tattcagaaa ttggccatca cttggggatt tggagagcaa gcagatctac taaactatca
    10501 acctgattat atcgctcaca aacccttaga agttttggcg tattttcaat agcatagact
    10561 gggtaacaat tccatttcag aagaaaatga agtaatactc aatgaaaatc aaagagcaaa
    10621 ctaggaaact agctgcgggc tgctcaaaac actgttttga ggttgcagat agaactgacg
    10681 aagtcagctc aaaacactgt tttgaggttg tggatagaac tgacgaagtc agtaaccata
    10741 tacggcaagg cgacgttgac gtggtttgaa gagattttcg aagagtataa gtctctacat
    10801 aataaaacgc atattaccaa ggttgtgtaa cttgatacta tgcgtttttc ttttttattc
    10861 aatgtgggtt gtttgattag caaaggcgat aatagcttgc ttcaactcat ctccactgag
    10921 agtgcggaac tctccaatct tttgattgat ggattctaaa ggcatgacat taaccttacc
    10981 aacgaaaatc ttatccataa cttgattatc aacgagttcg gttgatacca agagttcttc
    11041 gtagagtttt tcacctgggc ggattccaac ttcaacgatt ggaatttcac tttcagtgtg
    11101 gccacttaga agcaccatct tcttggccaa gtcataaatc ttgactggtt tgcccatatc
    11161 aaggataaag acttccccat ctttggcata agcaccagca tggataacca gacggctagc
    11221 ttctggaatg gtcataaaat aacgggtcat gcggaagtct gtcaccgtta caggcccacc
    11281 ttcagcaatc tgacgttcaa agactggaat gacactacca cggctaccaa gaacattccc
    11341 aaaacgaact gcacagtagg ttgattggct acgttggtta aagccagtga caatcaactc
    11401 cgccacgcgc ttggttgctc ccataacatt tggtggattg actgccttat ctgtcgaaat
    11461 cataaccatc ttagacactt tagcttcatc aacagcctta gcaacattgt aagttccacg
    11521 gatattgttt ttgaaggctt cttttggatt gcgctccatc ataggaacat gcttgtgggc
    11581 tgccgcatga taaacaatag caggtttgta ctgctcaaag acttgcaaca aacgatcata
    11641 gtcttgaatg tccgcaatca caggtacata atcaatccct tggaacttac gaatcaattc
    11701 atgataaaca aggtagattg agttttcccc atgaccgagc aagacaatgc gttcaggatt
    11761 gaagcgacta acttgacgac agatttcaga accgattgaa cctccagctc ctgtgactaa
    11821 gatggtctta cctgtcagtt ctgcacccag acgcgattcg tcaagacgga tttcctgacg
    11881 acccaaaagg tccgtaatat caattttttg gaagccagta cctgcttggt gaaggccctg
    11941 aacaacagtt tcaaccttag gcatcttgta acatttgaca cccagcttat tacacatctg
    12001 caagatacgc tcatattctg acggatccag cgacggaatc gcaacgatga cacgctcgat
    12061 ttgatggcgt ttggctaatt caggcagatt gtcataagag cccaaaacag gaataccacc
    12121 aagtttttga ccctttttct tagaatcctt atccaaaata ccgaccagtt ctaattcact
    12181 ggttggatgt tggtaactat ccataaaaag agccccacca tcaccggcac caatcaagaa
    12241 ggtccgacgg tgttctccat caccactacc ttttttgcgt ctggagtaga ttaactgcca
    12301 agtaatccgt ggcaataaaa tcaagaaggt actcaacaag ataaagagaa tgatgaaacg
    12361 gatggagaag agtggcaaga aggcataaca gatactatat gacaagacac tgctagcagt
    12421 cacaccaaaa aagattttca tgaaatccgt aatcttgctg taacgactaa tgctcgcgtt
    12481 caacccccaa aaaccaatca tcaattgata gaacaggaag gccaaactcg tatagataat
    12541 gtagtcaaca ggtgctggat taatcagccc ataaaataaa atataagata caatgatgga
    12601 aaccaccata ctgaaaatat caaatattcc ccagaaaacc tgcttttgtt gtttatttaa
    12661 aatttccacc agatcaatca cataatctgt tagtttttta ttcatagaaa tctactcctc
    12721 cttaaaagag ttttactata ttgttattat agcatatttt tgtttatttg gcttatttta
    12781 tccaaataaa ttattgttct cttgtactcc ttcttccatt taaatcctct aattaaacct
    12841 acaatcgtcc caaagccata agcaaagtga atggaaaata aaagaaaggg catcacaatt
    12901 agaaatccat ttttatgttt taataaagtc agcaaagtga gtagtgacaa aagtagaaaa
    12961 taggcaccta atagtaaagt tatgaatacg aatgtgatcg gtaacaatgc tagactaaac
    13021 acaagactca aaacaaataa acaaggaaca tagtgaaata atgataaaca cttaaactga
    13081 acatgacttg tcaagccaat ccacaaacca tttaaatact tttgatgcag cattttcttg
    13141 aatgttggtc gaatatactg ataagataga atacttgggc tatagcggat tttataacca
    13201 tattctcgaa ttctataatg aatatcatta tcttcagttc ggccaagttg ctcatttact
    13261 aaaccaacct tctggaaaac ctctcgttta tacattccat gaaaaataga agaaacatat
    13321 ctatcctcag aactatttcg ataattggca atgctactgc caaacatatt ttcctcaaca
    13381 agatgcaagg tctctgccca ttttcctttt ccttcgacaa tcgtcggtct aggcccccca
    13441 cagacaaatt caccttgttg aataatagcc acattgttca ttacaaaact ctcagtaact
    13501 tttgaatgag catcaatttt taaaataagg tcccctacag aatgtttaac tcccaggtta
    13561 aaaccactag cttgattttt cttaggattg ttatacaatc taattgagtt aaactctgta
    13621 tcttccttta taaattgctg aatgatagct gtggtcccat ctgtggacat agcatttata
    13681 aatagaattt caatattctc tttaggataa gtttgatttt ttaagtcttc aattagacca
    13741 ggcagatatt tttcttcatt gtatgcactg attacaatgg atacgagaag actttcaaca
    13801 ttttgagtca ctactactct cctgaatttt tccttccacc attctatcat aattttcaag
    13861 actttcccat ttttatcttg aaagccagaa accttacttg acattatagt gaaaaagcct
    13921 taaaataagc tgttattaaa atcagctaga agaggtatta tatgaaaaag caatcactct
    13981 tttttgttcc aggtattatc ctgattggtg tttccttgcg aactcctttt actgttttac
    14041 ccattatttt gggaaatatt tcgcaaggtc tggaggtaga agttagttcg cttggtgtct
    14101 tgaccagcct gcctctcctt atgtttaccc tcttttcacc attttctacc cgactggctc
    14161 agaaaatcgg cttggagcat ctcttcacct acagcctctt cttcttgacc atcggctcac
    14221 ttattcgact aatcaatctg cccctgctct atctaggaac cttgatggtt ggggcaagtg
    14281 tcgcagtcat caatgtcctg cttcctagtc ttatccaagc caatcaacca aagaaaattg
    14341 gttttctgac caccttatat gtaacgtcta tggggattgc aacggctctg gcttcctatc
    14401 tagctgtgcc cattacacaa gccagttctt ggaaaggact tatccttctc ctcacgttac
    14461 tctgtctagc aacttttttg gtctggctcc caaatcaccg ctataatcat agactagctc
    14521 cacaaaccaa acaaaaaagt caaataaagg tcatgcgtaa taaacaggtt tgggcaatta
    14581 ttatcttttc aggttttcaa tccttgatct tttacaccgt catgacctgg ttacctacca
    14641 tgtctatcca tgcaggtcta tccagtcacg aagctggctt gctgacttct atcttatctc
    14701 tgattagcat tcctttttca atgaccatcc caagcctgac aaccagttta tctactcgca
    14761 accgtcagct catgctcact ctggtttcac tagctggtgt ggtcggcatt tccatgctct
    14821 ttttcccaat caataatttc atttactggc ttgccatcca tctcctcatc ggaaccgcaa
    14881 ccagcgccct cttcccttat ctcatggtca acttttcact caagacaagc gcccctgaaa
    14941 agacagccca attgtccggc ctatctcaaa caggaggcta tatcctagca gcctttgggc
    15001 caaccctctt tggttacagt tttgacctgt tccactcttg ggtaccatct gtagctgccc
    15061 tcttgctcat cgatatcctg atgactgtgg ccctctttac agtggacaga gcggataaga
    15121 tcctttaaac ttctagtttt agctagaagt tttttatata taaaaatttt acacatttct
    15181 cttgacaggg ctttctttta gatgtacaat gtatgtgtag aaaaattata tataaaaatc
    15241 ttacacatta gaaaaggagg tttcccatgt actttccaac atcctctgcc ttgattgaat
    15301 ttctcatctt ggccgtactg gagcagggtg attcttatgg ttatgagatt agccaaacca
    15361 ttaagctgat cgctaatatc aaagaatcca cactctatcc cattctcaaa aaattggaag
    15421 gcaatagctt tctgacaacc tattctagag agttccaagg tcgcatgcgc aaatactact
    15481 ccttgacaaa cggtggtata gagcagctct tgaccctaaa agatgaatgg gcactctata
    15541 cagacaccat caatggcatc atagaaggga gtatccgcca tgacaagaac tgaatacctg
    15601 actcagctag aactctatct caagaaacta cctgaagctg accgtatcga agccatggac
    15661 tatttcagag agctctttga cgatgctgga gtcgaaggag aagaagaact catcgctagt
    15721 ttgggaactc ccaaagaagc ggcccacgaa gttctatcca atcttctcga taaaaaaatc
    15781 aatgaagcac ccgctcaaaa aaataaccga caaattttac atatcgcctt gttagccctc
    15841 cttgcagcac ctatcggcat tcctctggga atcgccatcc tcgtgaccct gttcgcaatc
    15901 cttgtagccg ctttgactgt cattctggct ttctttgcag tttccatact gggtatcatc
    15961 ggcggattcc tatttttagt tgaaagtttc actatcctcg cccaagccaa atcagccttt
    16021 atcttgattt ttggttctgg tttactggct atcggtgctt cttcgctagt tttacttggc
    16081 atttcctatg tagctcgctt cttcggtcta ctcattgttc gtctggtaca atttgttctt
    16141 aaaaaaggaa agagaggtaa tcagcatgcg taaatggaca aaaggatttc tcatctttgg
    16201 tgtggtgact accgttatcg gctttatcct gctttttgta ggtatccaat ctgacgggat
    16261 taagagccta ctttccatgt ccaaagaacc tgtctatgat agccgtacgg aaaagctaac
    16321 ctttggcaag gaagtcgaaa acctagaaat tactctccac caacacacgc tcaccatcac
    16381 agactctttc gatgatcaaa tccacatttc ttaccatcca tctctttctg ctcaccatga
    16441 tcttatcacc aatcagaacg atagaactct gagtctcact gataagaaac tgtctgaaac
    16501 tccgtttctc tcttctggaa ttggtgggat tcttcatatc gcaagtagct actctagtcg
    16561 ttttgaagaa gttattctcc gactaccaaa agggagaact ctaaaaggga tcaacatctc
    16621 agccaatcgc ggacaaacca ccatcataaa tgctagcctt gaaaatgcga ccctcaatac
    16681 aaacagctat atcctccgaa ttgaaggaag tcgtatcaaa aacagtaaac tcacaacgcc
    16741 caatatcgtt aatatctttg atacagttct tacagatagt cagctagagt caacagataa
    16801 tcacttccac gctgaaaata tccaagtcca tggtaaggtt gaactgactg ccaaagatta
    16861 tctcagaatc atcctagacc agaaagaaaa ccaacgaatt aactgggaca tctcaagcaa
    16921 ctatggttct atcttccaat tcacaagaga aaagcctgaa tcaagaggta cggaattaag
    16981 caacccttac aaaactgaaa aaaccgatgt caaggatcaa ctcattgcga gatctgatga
    17041 taatattgat ctaatatcca caccaagcag acgttgacaa aaacgcttac atctgctact
    17101 atggaagcat atttatctaa ccaaaaggag gttctaccat gaaacaagaa tggtttgaaa
    17161 gtaatgattt tgtaaaaaca acaagcaaga acaagcctga agagcaagct caagaggttg
    17221 cagacaaggc tgaagaaacg atagccgatc tcgatacacc aattggaaaa aatactcaag
    17281 tagaggagga agtctctcaa gctgaagtcg aactggaaag ccagcaagaa gagaaaattg
    17341 aaactcctga agacagtgaa gcgagaacag aaatagaaga aaagaaggca tctaattcta
    17401 ctgaagaaga gccagacctt tctaaagaaa cagaaaaagt cactatagct gaagagagcc
    17461 aagaagctct tcctcagcaa aaagcaacca cgaaagagcc acttcttatc agtaaatctt
    17521 tagaaagtcc ttatatcccc gaccaagctc caaaatctag ggataaatgg aaagagcaag
    17581 tgcttgattt ttggtcttgg ctagtggaag cgatcaaatc tcctacaagt aagttggaaa
    17641 caagtatcac acacagttac acagcctttc tcttgctcat tctgttttct gcatcttcct
    17701 ttttctttag tatctatcac atcaaacatg cttactatgg acatatagca agcattaaca
    17761 gtcgcttccc tgagcagcta gctcctttaa ctcttttttc tatcatctct atcctagtag
    17821 cgacaacact cttcttcttt tcattcctct tgggtagttt cgttgtgaga cgatttatcc
    17881 accaggaaaa ggactggacg ctagacaagg ttctccaaca atatagtcaa ctcttggcaa
    17941 ttccaatctt cctcactgct attgctagtt tctttgcttt ctttgatagc ctacgattta
    18001 cagccctctt gtgtgtgatt agcattggaa tcattctgct tgccagtctc catatcatta
    18061 caagaccaag tcaagcaagt gaaaccgact ccttctatca attattcttg tctgtccttg
    18121 tgaacggagt tattatcctc ctcttctttg tagctgaagt ggcactgatt ggagattatc
    18181 ttcgtatctt ggcctttctt taaaattcaa tcctgtcatc cttggcagga tttttctatt
    18241 tcaaaaaagc aagtcgattg acctgcttct gctttacttt tcttgtgcta atgttttaaa
    18301 atcttgtcct aggatgggtt gtacttctaa ttgattggcg tctagttggt ggtaaaatgc
    18361 tgatggtagt gactctagga attttgcata gtccaagcgg gcgatggctt catagtcttc
    18421 tggtttagag ccatctcctg tgatttgaac caagtcgatc tcccactgca cttccttatc
    18481 caccaattgc tccatatagg cagcaggaac aaatggttct ctcggtaaaa cggtcttgac
    18541 gccttgagcc aaatgataaa caccgtgcac ttgcccttct ccatcctgat agaaggaaac
    18601 tcttgcaaag taggcatctg tctcttgaac cgcacgcaca cgcgcttcaa actgggccaa
    18661 gccatctgcc tctaaaaagc ttttcaagtt ctcacgacta aagaaaatag gattaaaaat
    18721 tccttggcaa atcgtaaaac gagctacagg gtctgctaga taggcttgaa tacttgcttg
    18781 gaaataagct tcaaaatcaa aaccatctag cccttcaata tcagtccctg tataagcaag
    18841 caaagcatct aaaaatgact tgataatctg ccagtctgtc tttgttagta ggtcaggaag
    18901 atcgacacgg taagcctttt gaccatcagc ataactgacc ttaaaaagaa attgtgattg
    18961 ccccattatc gcacagacga ttaagaggct gacggagata gactacatca tagctatgtg
    19021 actccaaacc gtctagcaag gccaagatcg acttggcatt caaaatctct tgttctccta
    19081 aaatgctctg tttatttgga ataaaaaatg tttttgccat aactggactc ctttgaaatc
    19141 gtttacatac agtatacctt atttttctga aagatacaaa aacaaacttt atattcttcg
    19201 aaaatctctt caaaccgcgt cagcttcgcc ttgccgtaga tatatgtaac tgacttcgtc
    19261 agtcttatct acaacctcaa agcagtgctt tgagcagcct gcagctagct tcctagtttg
    19321 ctctttgatt ttcattgagt attagatttt tgagtacaaa gcatagaaaa acagcccctg
    19381 aggactgttt gatcttatac agtagctgcc tgatccaagc tttcaccgat agcggctagg
    19441 cgctcaatca cttcagcttg tgtcaattca ttttttgaaa catagcggtt acgtgggtga
    19501 acacggcact cgtgtgagca tccacgaagg tacttgtctt cattttcttc tgatgtcaag
    19561 atacgacggt tacagaaggg atttccacag ttgacataac gttcacatgg tgttccatca
    19621 aaccagtctt tccctacgat ggttgggttg acatggttga catcaacggc aatacgctcg
    19681 tcaaagacgt acattttccc atcccaaagc tcaccttgaa cttctgggtc tttaccgtaa
    19741 gttgcgattc ctccgtgcaa ttggccaaca tctttgtaac cttcacgaac catccagcct
    19801 gagaatttct cacagcgaac accacctgta cagtaaacca cgacacgctt gtccatgaat
    19861 ttttctttgt tgtcacggac ccattgtggt aactcacgga agttgcgaat atctgggcga
    19921 atagccccac ggaaatgtcc taggtcgtac tcataatcgt tacgtgtgtc aaggacaacg
    19981 gtatctttat caagaagcgc ttctttgaac tcttttggag acaagtaagc acctgttgtt
    20041 tcaagtgggt tgatgtcatt gtcaaagtcg ttgtcttcca aaccaaggtg gacaatttct
    20101 ttcttgtagc gaacaaacat cttcttgaag gcttgttcac tttcttcgtc aatcttgaac
    20161 cagagatctt ccattcctgg aaggctgtga acgtagtcca tgtatttttg agttgtttca
    20221 tagtcacctg aaactgttcc gttaattccc tcgtcagcga ctaggatacg gcctttaagg
    20281 ccgattgatt tacagaaagc caagtggtct gcagcaaatt gctctgcatt ttcaattgga
    20341 gtataaaggt agtaaagtaa gacacgaata tcttttgcca taagatttgt tctcttttct
    20401 attcttaaat tttctaaatt ttttatttat ctacactagt atacctgctt gagaaaacga
    20461 atgcaattta tttgactgga aattgtagag gattctcgaa atttcctgaa tggttaaaat
    20521 aaggacaaga gaaaacaggg atatctatat ccttgtgccc aaaaaaccac tgccctcccc
    20581 agaccaatct gaggaaagca gtgattctta ttttaggagt taggaatgaa tacacgaaat
    20641 caatttagct gattattttt tgtttttcaa gaattcatcg tattgttttt gcatttcgtt
    20701 caatactttt tcgtaggcac cttcagattt caatttttcc atcaattctg gaatcgcttt
    20761 atctgggtct acagtaccag tgttgatagc tgtatcaaat tgttgcattg tgttagcaat
    20821 agctgagatt tcagatttca cattgtcagt attaaagata aatccaagcg ctggagattc
    20881 tttagcttct gccaattctt tcttagaatt ttcgatttgt tggtctgtaa cgttttcgtt
    20941 gatgtaaagg atccagttgt taccagtgtt ccatccaccc atgtgagtgt ttcctttgta
    21001 gccatcaaga acgcgaacac ggttttcttt accttcaatt ttttcccagt tcttgccttc
    21061 tggaccgtaa acaagaccgt tcaagagttc tgggttcgta ttcaagaggt tcaagatttc
    21121 cattgatttt tctttgttct tagagttgtt tgagatgaca aagttagcaa cttgtgttgt
    21181 ttggtttttc ttgatgaagt tagtaattgg tttgatttgg atatctttgt tggcaacacg
    21241 tgaaagcaag ctgttaccgt agtcagctgg tcctactgtt tcttcacgaa cgaaccaagt
    21301 atcttgttga aggtcaaagg aagtatcgct tgttgcgacg tcttttggaa tgtagccagc
    21361 ttcatagaat ttgtgaagag tcttcaagtg ttctttgaaa cgaggtactt cgtaacggtt
    21421 tacaacttta gtagtatcgc cttcaaggtc aataacgaat ggaagaccgt ttgctactgg
    21481 gtagtcaaag ttatcagatg ggatgaaaac tttaccaata gcaaatggta ctacgtctgg
    21541 agctttttct ttgatttgtt tcaagactgg ctcaagagtt tcgtaagaag taacacctga
    21601 aatatcgata ccatatttgg caaggagagt tccgttgaag gcaaagtttt gagatgatgc
    21661 tacgttggct gcaactggta cagcgtaaat cttaccattt acagtattac ccttgatata
    21721 agctggatca agtgccttgt aaaggtcttt accttctttt ttgtacaatt ctgtcaagtc
    21781 agcataagca cctttttgag catttacaat atagttatct gcaaaggcga tatcatagtt
    21841 ttcaccagat gatgtgataa ctgacatttt cttaccatag tcaccccagc caaggtattg
    21901 gatatccaat ttagcaccaa ctttttcttc gatgattttg ttggcatttg ctaacaattc
    21961 atccaagtta tctggtttgt caccgatttg gtacattttg ataacaggtt tgtcacctga
    22021 atcagcagct tttttgctgt tacctgtcaa atttccacaa gcagcaagac ctgcagccag
    22081 agcgactaca ctagcagatg caaaagcata ttttttccag tttttcatga taaaaactcc
    22141 tttttttatt tttaaactta taaacaatgt aatgatctta tactcaatga aaatcaaaga
    22201 gcaaactaga aaactagtcg caggctgctc aaagcactgc tttgaggttg tagataagac
    22261 tgacgaagtc agttacatat atctacggca aggcgacgtt gacgcggttt gaatttgatt
    22321 ttcaaagagt attaacttca cacaagggaa gttgggaact gagaaatgtt ctttttcaat
    22381 aagcactatt ctttcacacc accgatagtc aaacctttta caaagtagcg ttggaagaat
    22441 ggatataaaa tcgcgattgg aagggtcgca accacaacca tggccatacg acctgtttct
    22501 ttcggtagag caactcccag ttgaccagtc aagccgaccg ctttggcaat gtagtccata
    22561 ttttgttgga tttgcatgag caaatattgc aatggataca agttgtcact cttgatgtaa
    22621 agaagggcgt tgaaccagtc attccagaaa ccaagagctg tcaaaagcgt gatggttgcg
    22681 atacctggta gtgacaatgg caaacagatt tggaagaaaa tccgggcctc actggcacca
    22741 tcgatacgag ccgattcgag aatggcttct ggaatggtct tcttgaagaa ggaacgcatc
    22801 aagatgatat tgaatggtga gagaagcatt ggaacaatca aggcccaaac agtgtcacca
    22861 agctgaagta cacgggtcac catgatataa cctggtacca aaccagcgtt gaacaacata
    22921 ctgagaagga cgaagatggt aaaaaatctg cgatacttaa aggttgtccg tgaaatagcg
    22981 taggcatagg ttgttgtgat aaagacattt gtcaatgtcc caactacggt tacaaagaca
    23041 gagatgaaga gggcttgtag gattttatcc ttaaactgtg ccaaaaactc aaaaccgtct
    23101 aagccaaatt gggatgggaa gaagctatag ccgtattgga ggaggctttt ctcgtctgtc
    23161 actgaaataa tgataacgaa tacaaaaggt aggatacaag agagggcaat caaacccgaa
    23221 atgatactga agaagatatc tgctttctta ctgaaggagt gaatgccgac attatcaatt
    23281 ttttcttttt taattttctt ttttgccata ttctcctcct ttctagaaca aagctgagtt
    23341 tggatcgact cgtcttgcaa gcaagtttga taggataacc agaatcaaac caacaacgga
    23401 ttggtaaaga ccggctgctg cagccatacc gatatctgct gtctgagtca aaccattaaa
    23461 aacatatacg tccaaaacgt tggttacatt gtaaagctga ccagcattgt gtgggatttg
    23521 atagaagaga ccgaagtctg cgcggaagat atttccgact gcaaggatgg tcaatacagt
    23581 tacaagcgga gtcaactgag gaatggttac gttgcgaata cgttgccact tgctagctcc
    23641 gtccactgtc gctgcttcgt agtaggttgg atcaattccc atgatcgtcg catagtacat
    23701 gacactgcta tatccaaaac ctttccaaat acctaggaaa agtaggagat agggccagat
    23761 gcccaggtca gcgtagaaat tgacttcttt gagaccaaga ctttccaata gatgattgaa
    23821 caccccttta tcaatattta ggaaggcatc tgtaaagaaa ctgatgataa cccaagacaa
    23881 gaagtaaggg aacaacatag aagtttggaa aatcttcacc attctcttag aacggagctc
    23941 gctgaggata atggcaatcc ctacagatac aactaaacct agaaagataa agccaagatt
    24001 gtagaggaca gtatttcgtg tgataataaa ggcgtctctt gaactaaata agaatctgaa
    24061 attatcgagt ccgacccatt tactatttat gatactatct atgaaaccat tactggtcat
    24121 gtggtagtct ttgaaggcaa ccacgttccc aaatactgga atgtaaaaga atagaatcaa
    24181 ccagagtgcc cctggcaaaa ccatcaagag aaagatccag ttgtctctca atgtttttga
    24241 aaactttttc ataatttcct ccctttttat tttgatatcc atctaaaaat tcttttttag
    24301 acttttgata acgattacat tattagtata ctcctatttg caggttaggt taaactccta
    24361 attatagaaa aaactccaca aattatgtag cagatttaaa actttatcac cactataaaa
    24421 caaatgtcct aaatcaattg tttattttat ctctattagc ccagtgatgg cgtcactctg
    24481 ttataagcat ccaacaacgg ggtatactga aaaatctcca gactagggaa ctcagcgata
    24541 gttcctaatc tggagatttt taatatgtta ttaggcgttt gctttcaact tagcaataac
    24601 ctctttaaga ttatcaatca actctgcttc agtatgctca gagccttttt catctgccaa
    24661 gaacaaaact gctttttgaa gttcttcttg agagttttca aggacatcct tatctactgt
    24721 ttcaaggttt gagtctttaa gaagtttact taattccttg gctaatttct tgagtttgat
    24781 ttgcagactc atcttctcct gctgtttctt tgcccgctgt ttgtcctcca tccttagttg
    24841 ctgactggct ttccttaatg gactctaggg aagcaatggc atctttgact gtttgcaaga
    24901 tatcacgtaa accttgctct gtcaaactat catctgcaag agctttctta gcctctgcca
    24961 aaaccagacg tgctgaatct gtggtaggat tcgatacacc tgtcaatgat ctcaaaagat
    25021 tttctaaggt ttgagtctgc ttactaatac tagactaaaa tcaaaaagca ttacataaca
    25081 gtgatatgaa atcaactaaa gaagaaatcc aaaccatcaa aacactttta aaagactctc
    25141 gtacagctaa atatcataaa cgccttcaaa tcgttctata gtaaaatgaa acaagaacag
    25201 ggcaaatctt ataaagagat tatagaactt ttatagta
//
LOCUS       DAVLMQ010000025        25026 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000025 DAVLMQ010000000
VERSION     DAVLMQ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25026)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25026)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25026
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.025"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(215..697)
                     /locus_tag="VXF95_001246"
     CDS             complement(215..697)
                     /locus_tag="VXF95_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081794.1"
                     /translation="MKSSFFHYLKEIILYGVLVPILTVIVGFHLFTTFYPISDSLLTD
                     FLKAFTEQRILAIVFVLILCFIFFGSIYYCISCGRNRKLIPDKVYTQITTYISSVGLG
                     TAVIAVATLTLTELQFSILTGWIAFIALLLPLLKFKVQYSTYQSSDNVAQKTTENKAN
                     "
     gene            752..955
                     /locus_tag="VXF95_001247"
     CDS             752..955
                     /locus_tag="VXF95_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1081795.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQAELAKQVSVTSSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            972..1169
                     /locus_tag="VXF95_001248"
     CDS             972..1169
                     /locus_tag="VXF95_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081796.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            1180..1341
                     /locus_tag="VXF95_001249"
     CDS             1180..1341
                     /locus_tag="VXF95_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081797.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDRKKRINEYKKIQDDEL
                     ERIRNKFNL"
     gene            complement(1336..1761)
                     /locus_tag="VXF95_001250"
     CDS             complement(1336..1761)
                     /locus_tag="VXF95_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081798.1"
                     /translation="MDYQILIQPAISVILAIISGLWSYIASKANNKAEIEKQAKEHSH
                     IVEKLEKEFHYQIDTLKQQHTLELEKVKQAHELRLQELEKVSQIDTETDKAMKMNDLI
                     YKTFTGEVDLDKALKLADKANNHKQKLNKKFIQKTSKKS"
     gene            1815..2525
                     /locus_tag="VXF95_001251"
     CDS             1815..2525
                     /locus_tag="VXF95_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HEV1081799.1"
                     /translation="MNEIFNFHGQEVRTLTIDDEPWFVGKDVADILGYSKARNAITLH
                     VDEEDALKQGIPTSGGTQDMLIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRKQ
                     GGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAQSLLKKRKAR
                     VVACLGGIDSPAYADKVFAQSVFRQAEIDFKDHFNISRYDLLPKKHADAALAYWMTWE
                     PSTNTKMKIMKLNSFDDV"
     gene            2539..2796
                     /locus_tag="VXF95_001252"
     CDS             2539..2796
                     /locus_tag="VXF95_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1081800.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCE
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            2882..3202
                     /locus_tag="VXF95_001253"
     CDS             2882..3202
                     /locus_tag="VXF95_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081801.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQGYNHAYERGREAERQEIRKNIRRPFKGFTYDNEPPQGLRPEPLALPEPKQSA
                     IRLL"
     gene            3218..3514
                     /locus_tag="VXF95_001254"
     CDS             3218..3514
                     /locus_tag="VXF95_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081802.1"
                     /translation="MEELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLLVKE
                     YLTDYEKLAKDYRYVTLKNKLLKIEKMELEGRHIYEDMRMKYRANRRKWGARYV"
     gene            3507..4313
                     /locus_tag="VXF95_001255"
     CDS             3507..4313
                     /locus_tag="VXF95_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HEV1081803.1"
                     /translation="MSEIKWIKITTDIFDDEKICLIDALPDPDAILVIWFKILTLAGK
                     HNSNGLLMMTDKVHYTDEMLATIFRRPLNTVRMAIGVFEQFGMIEIIDGIISLPNWEK
                     HQNVDGMEKIKEQTRNRVAKYRKKQKNLALGNVTGNVTVTDGNALEEDKDKNKNRLDK
                     DKNKKRITTTSSGSEENILELFQSEFRRLLSGFEIEEINHLLNENDVDLVKEALKTAI
                     NSGKPNIKYIGGILRNWQMNNVTTVEQVRQSEKKNKDKKEEQEAKDEWGY"
     gene            4301..4459
                     /locus_tag="VXF95_001256"
     CDS             4301..4459
                     /locus_tag="VXF95_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081804.1"
                     /translation="MGVLELIEQFEIDYYPLSYEKKTLLADQPIHQVVACLSEMASWH
                     ECGGRLVW"
     gene            4453..5223
                     /locus_tag="VXF95_001257"
     CDS             4453..5223
                     /locus_tag="VXF95_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1081805.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEVLKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            5432..6106
                     /locus_tag="VXF95_001258"
     CDS             5432..6106
                     /locus_tag="VXF95_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HEV1081806.1"
                     /translation="MMKFLNGDCMDIMKQYPDNYFDLAIVDPPYFSGPEKRKFYGRKI
                     SPIGVSRLYGEISEWKIPNRDYFDELFRVSKNQIIWGVNYFDYSFGSGRIVWDKVNGQ
                     SSFSDCEIAYCSYHDSTRLFRYMWNGMMQGKSISEGHIQQGNKALNEVRIHPTQKPVN
                     LYLWLLQTYAKEGDKILDTHVGSASSLIACGELGFDYVGCEIDKSIFNLAQQRLDAYE
                     KQLKLF"
     gene            6116..6334
                     /locus_tag="VXF95_001259"
     CDS             6116..6334
                     /locus_tag="VXF95_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081807.1"
                     /translation="MLELYFVYNGHCKFYLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGK"
     gene            6419..6586
                     /locus_tag="VXF95_001260"
     CDS             6419..6586
                     /locus_tag="VXF95_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081808.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            6754..7071
                     /locus_tag="VXF95_001261"
     CDS             6754..7071
                     /locus_tag="VXF95_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081809.1"
                     /translation="MMEELKRKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMAQVVIAVYLIY
                     GGN"
     gene            7073..7603
                     /locus_tag="VXF95_001262"
     CDS             7073..7603
                     /locus_tag="VXF95_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HEV1081810.1"
                     /translation="MNIKALIKKYEELWNEHSPFYEPVPYTSMVELFLKELKQLDEPQ
                     KVKIPQFVADWIEVCKEHLTTSLYTAMTPNFMKENNQSFDLILWIKKASNQDLFARAW
                     LDGYEVEKEKRYLVKIKGNIKENMLVYGELLERYFFTKSFSLDDAIYSHTRKELENAK
                     IGWVFDCEGFEIEEVE"
     gene            7603..7890
                     /locus_tag="VXF95_001263"
     CDS             7603..7890
                     /locus_tag="VXF95_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000194860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081811.1"
                     /translation="MTQTLEEGMKNQSKCIKVPREIRPFDIGYRIVNKYGQALALRNG
                     ASIFDLPFLAEKAIEKEFGKNDPDFDIGKHSVEEVAIVNLSKFHSYFEERV"
     gene            7921..9003
                     /locus_tag="VXF95_001264"
     CDS             7921..9003
                     /locus_tag="VXF95_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1081812.1"
                     /translation="MKFLDLFAGIGGFRLGMESAGHKCIGFCEIDKFARESYKAIHNT
                     KGEIELHDITAVSDESIRGIGSVDIICGGFPCQAFSIAGNRRGFEDTRGTLFFEIARF
                     ASILRPKYLFLENVKGLLNHENGVTFETIISTLDELGYNVEWQVLNSKNFGVPQNRER
                     VFIIGHLRREHTRRIFPLSGKNQSTSNQSVMKIGNINPSGNGMNGEVYQADGLAPTLT
                     TNKGEGQKIAIKSNTIKQFGVLQPNFNQCGVVYETDGIAPTIRAYQGGGLEPKIIQRG
                     HGYNKGGEHNIAPTLTSNSYHENNHLSDGFRIRKLTPRECWRLQGFPDWAFDKAQEVN
                     SNSQLYKQAGNSVTVNVIAAIAKELS"
     gene            9105..9383
                     /locus_tag="VXF95_001265"
     CDS             9105..9383
                     /locus_tag="VXF95_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081813.1"
                     /translation="MKRLGIIIGAVFVIVVSPFVVQYGWNEIITTIVPVGKITVWQAL
                     GMDALLSFIWPVLSSKKESEEDYSYAVKSSISKIITCAFLIWLASLFI"
     gene            9395..9805
                     /locus_tag="VXF95_001266"
     CDS             9395..9805
                     /locus_tag="VXF95_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081814.1"
                     /translation="MIPKFRGLSIDEKSKGEWQYGHLIEDRGRAFIINEVVEANEQYI
                     TIGSWCPVNPATLGQSTGLRDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTYIGGMP
                     AVYLKGFGDGYAWTEYEEIIGNVYENPELLEVNE"
     gene            9942..10343
                     /locus_tag="VXF95_001267"
     CDS             9942..10343
                     /locus_tag="VXF95_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HEV1081815.1"
                     /translation="MKKLSDEDLKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     SVGISKPTETIAVRIADDPTLKFLEGFKAIINKLLINLVDEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAILKGEL"
     gene            10531..11073
                     /locus_tag="VXF95_001268"
     CDS             10531..11073
                     /locus_tag="VXF95_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1081816.1"
                     /translation="MEFVSPIKDNDDIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            11450..11770
                     /locus_tag="VXF95_001269"
     CDS             11450..11770
                     /locus_tag="VXF95_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HEV1081817.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            11907..12299
                     /locus_tag="VXF95_001270"
     CDS             11907..12299
                     /locus_tag="VXF95_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HEV1081818.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYVDMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            12292..14022
                     /locus_tag="VXF95_001271"
     CDS             12292..14022
                     /locus_tag="VXF95_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HEV1081819.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            14030..14248
                     /locus_tag="VXF95_001272"
     CDS             14030..14248
                     /locus_tag="VXF95_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081820.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            14266..15468
                     /locus_tag="VXF95_001273"
     CDS             14266..15468
                     /locus_tag="VXF95_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HEV1081821.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDILYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            15452..16027
                     /locus_tag="VXF95_001274"
     CDS             15452..16027
                     /locus_tag="VXF95_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HEV1081822.1"
                     /translation="MQKRNSYRATQFQTREEESGDLVLSGYFIKFDEETELWRGYHEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFKL"
     gene            16024..17190
                     /locus_tag="VXF95_001275"
     CDS             16024..17190
                     /locus_tag="VXF95_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HEV1081823.1"
                     /translation="MNKALIFGARMRAKATKVVELEETIEELNKRSVVELEKLDRAKN
                     DEEVLAVEKTVDGLQREIEEKEAEKVQLENEIDELDKQIKEQNRKAPTPGKMEERGGK
                     TLGQREAFNHYLRTKEARADGFKSAEGEAIIPVELMTPKEAKQDKTDLTSLVNIVNVK
                     NASGKWSVVKLTDQAMNTVEELEENPELAKPTFTKVNYEIKTRRGHLPVSQEFIDDAD
                     YDVMGLVAKQTKNQERITKNKEIAKVLKTATSKSAAGLDGLKDILNVELKTYYNATIV
                     CTQSMFAALDKIKDKDGRYMLQTDITSPTGYKFAGRVIVVYPDDIIGESKGDLKAFIG
                     DVGEFATLFDRAQTTVKWQDDKIYGQYLATANRFDVVKVDGDAGFYVTYTDAVL"
     gene            17202..17471
                     /locus_tag="VXF95_001276"
     CDS             17202..17471
                     /locus_tag="VXF95_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081824.1"
                     /translation="MVYKVIRPFKDLRDPKKHCYKVGDNYPRVKHKLDKEFAETLLNG
                     ANSAGSIFLMNVEDKDMSKDDTLTTEVEKEETKVVDGKPEEGDEE"
     gene            17474..17755
                     /locus_tag="VXF95_001277"
     CDS             17474..17755
                     /locus_tag="VXF95_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081825.1"
                     /translation="MDNVQLLELLKLKLGIATKLRDKPLEKIIEAVKTELEDNLGVLL
                     DLDSSEDQMFVVDFAAFRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            17742..18041
                     /locus_tag="VXF95_001278"
     CDS             17742..18041
                     /locus_tag="VXF95_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HEV1081826.1"
                     /translation="MWNHEITLISKEVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            18038..18397
                     /locus_tag="VXF95_001279"
     CDS             18038..18397
                     /locus_tag="VXF95_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HEV1081827.1"
                     /translation="MSLTSDLANEIAKAMAEYSAEVEDKIDLIAEDVVNEAVTELKAT
                     SPKRHGKYARNWRFKKNAKGSYVIYNAAPTYRLTHLLENGHVLRNGGRSRAFPHIKPV
                     EEKVKENFEKRIKEIGK"
     gene            18394..18717
                     /locus_tag="VXF95_001280"
     CDS             18394..18717
                     /locus_tag="VXF95_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081828.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPNLPYLVYYESIPAINA
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            18729..19307
                     /locus_tag="VXF95_001281"
     CDS             18729..19307
                     /locus_tag="VXF95_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1081829.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIDLTL
                     DTKGETTTIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            19319..19738
                     /locus_tag="VXF95_001282"
     CDS             19319..19738
                     /locus_tag="VXF95_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081830.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSENPHIKPYEQFFMEME
                     VFPIQEVGPVLMEMLNASMTTKKHQMNQNQLAKKSSQ"
     gene            20016..22775
                     /locus_tag="VXF95_001283"
     CDS             20016..22775
                     /locus_tag="VXF95_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HEV1081831.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANRM
                     EAELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAEALDLTSRATRAAADGAAFYDKSIESVTESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFSSLPAPVKDFVVILGTV
                     VTAVGVIAPIFLSLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILEVINAVVSEISNFVMSIFGTVVAWWTENQELIRASAETVWN
                     AIYTVISTILEILGPLIQAGWDNIQLVITTAWEIIKTVVETAINVVLGIIQAVMQIIN
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRKTQL
                     RAGVT"
     gene            22772..23494
                     /locus_tag="VXF95_001284"
     CDS             22772..23494
                     /locus_tag="VXF95_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1081832.1"
                     /translation="MIKHNELVIDGVRTSSFPFKVIVHDSPSIALGESKTALLEHGGI
                     SGAIVQTNKHRELVKKSYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVTDLEEVQPGLYMTKATFTCHPTKYFKATDTQRLTRSGTLNVQGSALAFPKITIVG
                     QSVVETSFTIAGQVIRLEKLSESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            23495..>25026
                     /locus_tag="VXF95_001285"
     CDS             23495..>25026
                     /locus_tag="VXF95_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HEV1081833.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKEIMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALSRMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIVGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKNYQRTKNSQNVVTRIHAKSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQAKFSNEGIDKISDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDVFKKAIAYEFDALKEEYISLILDDKAGAGG
                     SRTSGGLSSAADAILGVTESAQEVALEKALQNADLDFDHKAGLLRQEISDGIELAKAK
                     AEEVKQELSDTINQRFNSFDNGPLKEAKRRAEEALRNAGASSLLAQEAKRIGLDSVAR
                     LEEFKSQTTSAQTALSGDLDALKRTIVNDIRPKQAQVEAEIAKQVEALVQTKKELSGA
                     STL"
BASE COUNT         8240 a         4152 c         5790 g         6844 t
ORIGIN      
        1 attcgtaagc taaagagtta gcgaactaga caactaaaaa ataaagcctt acaaaactga
       61 ttggcgtccg tttactgtag gtaaaactta cttttagtag gtcttttctc tatgttttta
      121 ttttaaaaca tttgactaga gttgtcaaga agttcgctaa ctttttagat aattttttaa
      181 aagaaagggg gagaggagaa tggtagagcc tttcttaatt ggctttgttt tcggtagttt
      241 tctgtgctac attgtcgcta ctttgatagg tgctgtattg gactttaaac ttcagaagtg
      301 gcaacaacaa agcgataaaa gcaatccaac ctgtaaggat tgaaaactgt aattctgtga
      361 gagtcaaggt agcgacagct atcactgcag tccctaaacc tacagatgaa atgtaagttg
      421 tgatttgtgt ataaacttta tcaggtatca attttctatt tcgtccacat gaaatacagt
      481 aataaattga accgaaaaat ataaagcaaa gaataagaac gaatacaata gcaaggattc
      541 tttgttctgt aaaagctttc aagaaatctg ttaacagtga atcagaaata ggatagaagg
      601 tagtaaaaag gtgaaatcct acgataactg tcaaaatcgg aactaggaca ccatataaga
      661 tgatttcctt tagatagtga aaaaatgaag atttcattat tctcctccaa tcgtttttat
      721 tttaattata tcaaatttag aaaggaaaaa tatgagtaaa gaactaaaga taatcaaggc
      781 taaaatcaaa actcgtttga ttgagctgga tatgactcaa gccgaattgg caaaacaagt
      841 atctgtaaca tcatcagtta tttcagaact gctgaagtat ggaaaaggaa gtgattatgt
      901 gaaagaaaaa gtcgtagata ttttgggtat tgaaaaccct tgggaaaata gttagagcat
      961 gaggaaatag tatgaacaac gcagcgcaaa aagtaacacg gattgacaaa gatgcctggg
     1021 agattgctac ggagttggcg aacgagtacg gggtatctat ttgtcacatc atcagtgaga
     1081 gcgtccgcta ctgtgcagag aatgccgaat ttaaggagat ggacgttgtc gttaaacgat
     1141 tggtagtcgg cagtaaggtg ctggagtagg agggtggaga tgaatgaact agtatggttt
     1201 tactttgttg tcataatcaa tcttatcatt ggttttgcta catactacgc tagcaaaaga
     1261 gacagaaaaa agcgcatcaa cgagtataaa aaaatacaag atgatgagct tgaaagaatt
     1321 agaaataaat ttaatttatg attttttaga agtcttttga ataaattttt tatttagttt
     1381 ttgtttgtga ttgttagctt tatcagctaa ttttaaagct ttgtccaaat caacttcgcc
     1441 tgtaaaagtt ttgtagataa gatcattcat cttcatagcc ttgtcggttt cagtatcaat
     1501 ctgagatacc ttttcaagtt cttgtaaccg taattcatga gcttgtttga ctttttcaag
     1561 ttccaaggtg tgttgttgtt tgagagtatc tatctgataa tgaaattctt tttcaagttt
     1621 ctctacgata tgtgaatgtt ctttggcctg tttttcaatc tcagctttat tgttagcttt
     1681 tgatgcaata tatgaccata aacctgagat tattgcaaga atgacactaa ttgcaggttg
     1741 aataagaatt tgataatcca taagatttct ccaatcgttt tattttcatt ataccaaatt
     1801 tagaaaggaa tactatgaac gaaattttta attttcacgg acaagaagtc cgtactttga
     1861 caattgatga cgagccgtgg tttgtcggga aggatgtagc ggacatccta ggatatagca
     1921 aggctagaaa tgcgattact cttcacgttg atgaagagga cgccctaaaa cagggcatcc
     1981 ctactagtgg cggaacacag gatatgttga tcatcaacga atctggtctc tactctctca
     2041 tcttatccag caagttgcct caagctaagg aattcaagcg ctgggtgact tcagaggtct
     2101 tgccagctat tcgcaagcag ggcggattta tccgcgagga cttggacgag gatgccttta
     2161 tcgctctatt cactggtcaa aagaaattgc gtgagcaaca ggctaccatg ctggaagata
     2221 tcgactatct aaagagtgag caaccgattc atccaagcta tgctcagtcg ttactgaaga
     2281 agcgcaaagc tcgggtcgtg gcttgccttg gcggtattga cagtcctgct tatgcggata
     2341 aggtttttgc tcaatcagtc tttagacaag ctgagattga tttcaaagac cacttcaaca
     2401 ttagtcgcta tgacttgcta cccaagaagc atgcggatgc cgctcttgct tactggatga
     2461 cgtgggagcc aagcactaat accaagatga aaatcatgaa attgaactca tttgatgacg
     2521 tctagaaagg ggaagaagat ggacaatgtt ctactttcac tgtctgaatg gattaaatct
     2581 attatcaagg acacaatcac aaggctagtc gaaatagaaa aagatagtga tcactatcca
     2641 gagttgatgg atgtgaacac tacctgcgaa tttctaggaa ttaagtatgc caccttttca
     2701 gataattatc gttacttaaa gggatttcca aaggaattac ctggtaagaa atggtcaaaa
     2761 agagccatca aagaatggct ctctaatcaa atataataac tttactaaaa ggcttctgga
     2821 caaggtctta gcaaaattat ttgactatat tatagcacaa aaagaggata aggagataaa
     2881 aatgtttgaa ccaccgattt tagaccagtt gatgggggtt ggagccttac tgcttggatt
     2941 tgcaggggct tgccgtcata tcaaattgca ggaacaacgc aaggaagaag aaagacgaga
     3001 agagcaagaa tttgcgtcta tgattattca aggctataac catgcttacg aacgtggtag
     3061 agaagctgaa cgtcaagaaa tccgcaagaa tattcgtcgt ccgttcaagg gctttaccta
     3121 cgacaacgaa ccgcctcaag gattgcgtcc tgagccatta gctttgccag aacctaaaca
     3181 gtctgcaatc agacttctgt aatgaggagg gcaggaaatg gaagaattga ttgaatcgct
     3241 ggataacctg attatgattg ttaaagaact ggaaggaagg gaatcaactt caagacattt
     3301 tattacgata tgggaaaacg attataaaaa tctattacta gtcaaagaat acctaaccga
     3361 ctatgaaaaa ctagcaaagg actatcgtta tgtgaccctt aaaaataagc tgctaaagat
     3421 tgaaaaaatg gagctggaag gcaggcacat ctatgaggat atgcgtatga agtatcgtgc
     3481 caatcgcagg aagtggggtg ctcggtatgt ctgaaattaa gtggataaaa atcacaaccg
     3541 atatttttga cgatgaaaag atttgcctga ttgatgcctt gcctgatcct gatgccatct
     3601 tagtgatatg gttcaagatt ttgacacttg ctggaaaaca taacagtaat ggtttgttga
     3661 tgatgactga taaggttcac tatacagatg aaatgttagc tactattttt cgtagaccat
     3721 tgaatacagt aagaatggct attggagttt ttgaacagtt tgggatgatt gagattatcg
     3781 atggtattat tagcttgcca aattgggaaa aacatcaaaa cgttgacgga atggagaaaa
     3841 tcaaggaaca gacacgtaac cgtgtagcca aataccgtaa aaaacaaaaa aatcttgctc
     3901 ttggtaacgt tacaggtaac gttacagtaa cggacggtaa cgcactagaa gaagataaag
     3961 ataagaataa gaatagatta gataaagata agaataagaa aagaataact actactagta
     4021 gtggtagtga agaaaatatc ttagaacttt ttcaatctga gtttcgtaga ctcttatctg
     4081 gatttgaaat tgaagaaatc aaccatctac taaatgagaa tgatgtggat ttggtgaaag
     4141 aagcattgaa gactgctatt aactcaggaa agccgaacat caaatatatt ggtgggattt
     4201 taagaaattg gcagatgaac aatgttacca ctgttgaaca ggttcgtcaa tcggaaaaga
     4261 agaacaagga taagaaagaa gaacaggagg ccaaggacga atgggggtac tagaactaat
     4321 tgaacaattc gagattgact attatccgtt aagctacgag aagaaaactc ttttagcaga
     4381 ccaaccaatt catcaagtgg ttgcctgctt gtctgaaatg gctagctggc atgaatgcgg
     4441 aggtcggcta gtatggtaga caatgtgttt gaggaaatcg ccttatctta tcgtaggaat
     4501 acagaacaac aagaagagtt ctgcgaaaag cataacatcc ctttgataaa gatattgagg
     4561 accgagagtg ttgtatgtcg catgtgtgaa tctgagcgga ttcatgaaga aaatcaggaa
     4621 agagtgaatg aactggctaa tgctgagaat gagcgagaga ggaaatacta tcttgaaaag
     4681 ttctctcttt atgatgaagt tttgaaaaat gctactttgg acaattttga aacaccaacc
     4741 gaaaaagaag cggaaaagct agcttttgca aagaggattt gtcgtgagtg gtctgagggt
     4801 gctaggaaca acatcgtgtt acaaggagaa gctggaacag gtaagagcca tttggctttt
     4861 gctatggtta aggctctatc tgagtacacg aaagagattg ctatttttat taacgtaact
     4921 gacttgctga tgaagattaa agctgatttt agtcaggaag agtttctggt caataaaatt
     4981 gctagtgcta agttcttggt tttggatgat ttaggaatgg aaaaagatag cgaatggtca
     5041 tttactattc tctacaatat cttgaataag cgttcaaaca caatcattac cacaaatttg
     5101 atttctgccg atattcaaaa aagatatggc agacctttca tgtccagact aatgaagggt
     5161 gtagataaag accatttgat ggttttcaat gatttgacaa acaagcgaaa gcaatatttt
     5221 tagaataggg gtggctgatg tttattttaa agcatgggac aagagaggat aagccgtttc
     5281 taaggtctgc aattatcagt gtgactggct tggatatttc gtgttccgag gagaagaaag
     5341 ccatgcggtt tatttctcgg gcggctgccg tacaggttgg aaaggctttg aggggttcct
     5401 ttgggaactt ttaccctgtt gaggtggagt gatgatgaaa ttcttaaatg gtgactgcat
     5461 ggacatcatg aaacaatatc ctgataatta ctttgaccta gctattgttg atccaccata
     5521 tttttctggt ccagaaaaaa ggaaatttta cggacggaaa atcagtccaa taggtgtaag
     5581 cagactctat ggcgaaatct cagagtggaa aattccaaac agagattatt ttgatgaact
     5641 tttcagggta tctaaaaatc aaattatttg gggtgtgaac tacttcgact attcttttgg
     5701 ttctggccgt attgtgtggg acaaagttaa tggtcaatca agtttttcag attgtgagat
     5761 agcgtactgc agttatcatg atagtactag gctatttcgt tacatgtgga atggtatgat
     5821 gcaaggtaaa tcaatctctg aaggtcatat acaacaagga aataaggcat tgaatgaggt
     5881 tagaatccat ccgacacaaa aaccagtcaa cctttacctt tggttattgc aaacttacgc
     5941 aaaagaaggc gataaaatac ttgatactca cgtcggttca gcaagtagct tgattgcttg
     6001 cggagagcta ggatttgact atgttggatg cgagattgat aaaagtattt tcaacctcgc
     6061 tcaacagaga cttgatgctt atgagaagca gttgaagtta ttttaggagg tattgatgtt
     6121 agagctttac ttcgtctata acgggcactg caagttttac cttgggaggt ttgacaatgt
     6181 cgatgatctc attgagcaga tggaagatca tcagtgggct ttctcggcta tcactcatcc
     6241 aagatttcag aagcacattg gtcagcggac gacacgattt gactacggtt ctaaggattg
     6301 ttactattta gcgacttttt caggagggaa ataatggcta aaaatatttt aatggattta
     6361 gcatttgaga attttcacaa atgtatggga atttctgatt tagtgggagg taagaaacat
     6421 ggttggagta acctatcagg aaattcatct ctttgttgaa tttttgaaag agcagtacgg
     6481 gcaaggtcgt ccagactata ttgaagccct gaacgactta gacggtctgg tggaagtctc
     6541 ctacagagaa gctattgaaa ggtttttaga agatgaagta cgataaacag gctgagattg
     6601 acggactgaa acgcacgatc gatcaaaacg aagagaagat aatcgagtat tcgaaaccgt
     6661 gcgatgcacg caagagacgt attagagcgc tagagcgcga tttgttgagg aaaaagaata
     6721 aagaattgag acggaaagtg gaggagttgg aagatgatgg aagagttaaa gcgaaaagtt
     6781 aatgaagtat acaactggac ggtagaagac gggaagccgc aacctcccaa gcaagattta
     6841 ccacaagcgg tgaaagaccg ggcggactat ttttgggaaa tggcagaaga tggtatgacg
     6901 tttatgggag cgatggaatg tatcttcgct gatgaaaagc ctacagacta tgatttggga
     6961 gctactaagg gttggttgcc aaaatctaag gagtttgatg attgggttgg ctattcgcca
     7021 agcatggctc aggtagttat tgcagtttat ttgatttatg gaggaaacta agatgaatat
     7081 taaggcattg attaagaagt atgaagaatt gtggaatgaa cacagccctt tttatgaacc
     7141 tgtaccttat acttcaatgg ttgaactttt tttgaaagag ttgaaacaac tagacgaacc
     7201 ccaaaaagtc aaaattccgc agtttgtggc ggattggatt gaggtttgta aagaacattt
     7261 aacaactagt ctatatactg ctatgactcc aaactttatg aaagaaaaca accaaagttt
     7321 cgatcttata ttatggatta aaaaggcgag caaccaagac ctcttcgctc gcgcatggct
     7381 tgacggctat gaggtcgaaa aagagaagcg gtatctggta aagattaaag ggaatattaa
     7441 agaaaatatg ttggtttatg gagaactttt ggaaaggtac ttctttacaa aaagctttag
     7501 tttagacgat gctatatatt cccacacccg taaagaacta gaaaatgcaa aaatcggctg
     7561 ggtgtttgat tgtgaagggt ttgagattga ggaggtggag tgatgacaca aacacttgaa
     7621 gaaggaatga agaatcaaag taaatgcata aaagtcccaa gggaaatcag accgtttgat
     7681 atagggtatc gaatagtgaa caaatacggt caagcgctcg ctttaagaaa tggggcaagt
     7741 atattcgatt tgccttttct ggctgaaaaa gctatagaaa aagaatttgg gaagaatgat
     7801 ccagactttg acatcggaaa gcattctgtt gaagaggtcg ctattgtcaa tttaagtaaa
     7861 tttcatagtt attttgaaga acgtgtatga gaaagtgaaa gttggggatg aggtgatgtt
     7921 gtgaaattct tggatttatt cgcaggaatt ggcggttttc gtttaggaat ggagtctgcc
     7981 ggccataaat gtattggctt ttgtgaaatt gataagtttg ctagagaaag ctataaagcg
     8041 atacacaata cgaaaggaga aatagaatta catgacatca cagcagtatc agatgaatct
     8101 attcgaggaa tcggaagtgt ggacattatc tgtggaggat ttccgtgcca agctttctca
     8161 attgcaggaa acagacgagg ttttgaagat acacgaggaa ctttgttctt tgaaattgct
     8221 aggttcgcat ctattctcag acctaaatat ctattccttg agaatgttaa aggattgctc
     8281 aatcacgaaa atggagttac attcgagacc attatctcaa ccttggatga actggggtac
     8341 aacgtggaat ggcaagtgct taacagcaag aatttcggag tcccccaaaa tcgggaacga
     8401 gtgttcatta tcggacatct tagaagagaa cataccagaa gaatttttcc tctcagcgga
     8461 aaaaatcagt caactagtaa ccaatcagtc atgaaaattg ggaatataaa cccatctggc
     8521 aacggaatga atggggaagt ctatcaagct gatggtctag ctcccacgct aacaacaaac
     8581 aagggagagg ggcaaaagat agctataaaa agcaatacta taaaacaatt tggggtattg
     8641 caacccaatt ttaaccaatg tggggtggtt tacgaaacag acggcatcgc accaactatc
     8701 agagcctatc aaggtggagg acttgagcct aaaattattc aacgtgggca tggttataat
     8761 aaaggcggag aacataacat cgctcctact ttaactagca atagctatca cgaaaacaat
     8821 catttatcag atggatttag gattagaaag ctaacaccta gagaatgctg gaggttacaa
     8881 ggttttcctg attgggcttt tgataaggcg caggaggtca actctaacag tcaattatat
     8941 aaacaagcag gaaatagcgt gacagttaat gtcatagcag caatagcaaa ggagttatca
     9001 tgaacacaat agagaaagtc aaacaatggt ttattgaccg tgatttagaa aacggtaggg
     9061 tcgttggatt gatggtgctt tcgtcaaaga ggaggattta taaaatgaaa agactaggaa
     9121 tcattattgg ggcggtattt gtaatcgttg tatcgccgtt tgtagttcag tatggatgga
     9181 atgagattat cacaacaatt gttccagttg gtaaaattac agtctggcaa gcattaggga
     9241 tggatgcact actatctttc atctggcctg tgctatctag caaaaaagaa tctgaagagg
     9301 attattcgta tgcggtaaag agcagtattt caaaaatcat tacatgtgca tttttgatat
     9361 ggttagctag tttgtttatt taaggagtgt tagcatgata ccaaaattta gagggttatc
     9421 cattgacgaa aaaagcaaag gagaatggca atacggacat ttaattgaag atagaggaag
     9481 agcatttatt atcaacgaag tggtagaagc caatgaacaa tacattacta taggttcttg
     9541 gtgtcctgta aatccagcaa cattaggaca atcaacagga ctcagagaca agaacggcaa
     9601 ggaggtattc atcggtgaca tcgttaaatg tacaagagga tgtctccatg aagtatattt
     9661 agaaaaagaa tacggtggca catacatagg tggaatgcct gctgtatacc taaaaggatt
     9721 tggagatgga tatgcgtgga cggaatatga ggaaatcatc ggcaatgtct acgaaaatcc
     9781 ggagcttttg gaggtcaacg agtgagatat tttaaaatac tatgtttggt attactgaac
     9841 aaacagttag attttatgga acgaagacaa gtaggaatag atatccgatc tcgacaattt
     9901 tgataacttg tttacatttt tgaaaaactt ggaggtggaa attgaaaaaa ttgagcgacg
     9961 aagacctcaa aacattagac agagaacttt tcaaatttca aaacattcaa cgtacaatag
    10021 atttgagaag actagaatta gaaactcgaa acccagatgc tcagagtggt cccagcgtag
    10081 gaataagcaa acctaccgaa actatcgcag tcagaatcgc agatgatcca accttaaaat
    10141 ttctcgaagg gttcaaagct attattaaca aacttttgat caatctagtt gatgaagata
    10201 aggaaatctt taatctgcgc tggagatatc ctcaactgag atgggaagaa atagcagaac
    10261 agaaattcat gagcaaagct acaatctatc gacgtagaag aattatctta gaacagtacg
    10321 ctatactgaa aggtgagttg taaataagat tgagacaaaa gacatcttga agtctcacaa
    10381 aaaaaggtct attatgatag catgaacttc tgaaacaaaa acacaaatca catgttggag
    10441 tcatcctatt tttacagaaa agttgtttaa cagaggaaca tcatgagtca gcaaccagct
    10501 ggctttttgt tttgtagaaa ggaggcagtt atggaatttg tatcaccgat aaaagacaat
    10561 gatgatattc aagctatgaa agattatctc agagaatgga atgagatgta ttatatgcta
    10621 ttcatcacag gcctgaatac tggcttacga gtcggagata tacttacctt gaaagttaaa
    10681 gatgttcaag gttggcacat caaactgaga gaacggaaga ctggcaagca gataacaaga
    10741 cggatgacaa aagaactcaa gaaagaaatg aggagatatg ttgaaggcaa accatttcat
    10801 catttcttat tcaagagtag gcaaggtcag aataaagcga tcactcgtga gcgagcctat
    10861 caaatcatac atgaagcagc tgaagaactt ggcattgata atgttggcac acatacaatg
    10921 cgcaagacat tcggctataa atattacaac aagacaaagg acgtaggaac attacagaaa
    10981 atgttcaatc actcatcacc tgcaatcacc ctgagataca tagggataga gcaagcagag
    11041 cttgatgacg cactacggaa ctttgtcatt taatttttta gatattactt tcacataatg
    11101 agttaagcat aaactaaaaa aatgaaactc ttcaaaaccc atgcttagta agggtttgag
    11161 attcagagtg agtttaacaa aatataagat atgtgaaagt gagggataaa attggtatag
    11221 ttacaagagg tgaaaaatgg taaaagaata ccgtatttgt aaatggaatg catataccgt
    11281 taacagccat actagtaaaa tggaataatt tttttaaaga atcagaatga gacaaaagac
    11341 atcttgaagt ctcacaaaaa aaggtttatt atggtagcat agatttcttg tatgaggagg
    11401 ggataggtca aaggcctgtc ccttttagca ttgagaaagg aggtttgaga tgtataacaa
    11461 acctatcaga ccatccttga aatctaagaa gtgggagaag ttccgtgata ggataatgcg
    11521 taagcatgat tatctttgcc aagaaagttt gcgttacgga atttctgttc aagcagaaat
    11581 ggtacatcat atctttcctg tgtctgaata tcctgagctt gaatttgttg aatggaattg
    11641 cttgccattg acgaataaga aacataatac gtttcatgat agagtgaacg atagagtaat
    11701 caaccaagga ttgtattggc agaaaaaaag aaaaaaagaa tttttaaatt ttttcaaaaa
    11761 tgaaaaatga aaatttttaa tcccccctct ttttgaaaaa tcattttggc cagtagggta
    11821 ccggtgaagg gaactttttc caagtcgggg gccttcaaac aaaaaggggg taaaaactaa
    11881 gcgattttga cgaaaggagg tagtttttgg ctaaaccaat tacagcaaag tcgattaagt
    11941 caaaagtggt caagcagatg aaagacttgg gaacttatcg taaagagttc gaaatgatca
    12001 ttgacatttt tgcaggtatg ttataccagt atcagaaact tgctcaagat tatgttgata
    12061 tgggttatcc agtaacagac acctacgtca ataaggctgg tgctgaaaat gagcgcaaag
    12121 ttccaatctt gacagcgatg gaaattttga ggaaagatat actcagctac tctaatcagt
    12181 tgatgatgaa tcctaagtcg ctcggtgagg tagtagaaca agagggtgag tcagttctta
    12241 ctgaggtact gaagttcaag aacgaaatca agaagaagcg agtgactggc aatgggtaat
    12301 cttgataaag ctaaaaaata cgctcaacac gtcttaactc accgagaaga acattgcgaa
    12361 gaaaacatcc ttgctgctga acgttttttc cgtgatttag aaaatccaac ctttgagatg
    12421 gatgaggata tggtggattt tgttattcac tttatcgaga acgtgatagt tcatcagcag
    12481 ggcgatgata tgtttgcggt atctatccgt aacaagccat tgcttttgca accgtggcaa
    12541 catttcgttg tagttaatct gtttggtttt tactacaagg gtacgaatga gcgcaggttc
    12601 aaagaagcgc tcatcatgct tgctcggaag aatgggaaga cctcgtttac tgctgcaatc
    12661 gcacttgctt atcagatatt agatacagat agcggttcca aatgctatat cgttgctaac
    12721 tcagtcaagc aagcgatgga agcttttggt tttttaagat tcaacgttga acgctggaac
    12781 gataagaaca ttcgtatcaa ggataataac caagaacact ctatcaccgc caattttggt
    12841 gatgaaggtt ctttctttat ccaggcttta gcgaatgatg agagccgtct ggactctttg
    12901 aacggaaatg ttatcatctt ggacgaagct cacacaatga ggaacagtaa gaaacatggt
    12961 cttatgaaaa aaacaatgtc agcataccgt aacagtatgc tttttgttat ctctacagct
    13021 ggggatattc ctaccgggtt ccttgctaac cgtctgaaat actgtcaaaa ggtgctcaag
    13081 caattagtca ctgatgattc atttttcatc ttcatctgta aggctaatca atctgctgat
    13141 ggggacgtgg tgaactatct ggacgagaat atcctcaaga tggctaatcc gtcatggggt
    13201 gtcacggttt cgctcaaggc tctcaaggaa gaagcagagc aggctatgaa tgatcctcag
    13261 acaagaaatg agtttttcaa taagaccttg aatatcttca ctaactctat gaacgcttat
    13321 tttaatcctg atgagtttat tgcgtcggat agttgctacg attggagttt agaagagctg
    13381 gcacgtttgc ctattcgttg gtatggtggt gcggacttgt caagattgca cgacttaaca
    13441 gctgctgctc tctatggtgt ctatcatgac ggtgagaaag acgttgatat ctgtatcaca
    13501 catgctttct tccctcggat taatgctcag aaaaaagcta atgatgacgg gattccactc
    13561 tttgggtggc agtctgacgg ttggttgacg atgagcaaca ctccgaccgt cctctatgat
    13621 gatatcgtca aatggttcat caagatgagg gagaaagggt tcaagattgc tgctgtcgga
    13681 atggatagga agtttggccg tgagttcttg acgaagatga aacaagctcg gttcaagatg
    13741 attgaccaac ctcagctttt ttatctgaaa tcagagggat tcagacggat tgagtttaaa
    13801 gttaagaata aagaatttta ctatcttcat tctgatgctt acgaatactg tgtgagcaat
    13861 gttagagcaa ttgaaaaggt ggacgatgct gtgcaatatg agaaattaga tggagacggt
    13921 gggactgcaa ggattgactt gtttgatgcc agcgtctttg cttgtataca ggctcttgct
    13981 aatcttggca agggtggtga tgtgatgaga ttctttgatt aggtgaatta tgaatgaaat
    14041 agtattatca gaacatgaaa ttaacttgct gatcaacaaa gggcgagtta aagtaatttt
    14101 aaacggggaa gtagtaacta ttcgtcaaag acatatgaaa aatttgatgg ctgaaacagt
    14161 aaaatgggaa aaacaggtaa ttgatgtcag tcagaatatc gtaagaaata aacactttga
    14221 ttcacttttt caaaatactt ttcgttagaa aggaggtgag gaaacatggg tatttttgaa
    14281 aagttttgga aacgaaacaa gccaagtaag tcaatcaaca tgctgagtca ttcagattta
    14341 gggttgtcaa acctgatgga ctcgtatgta cctttggcca gaaatccaga tgtggtgaca
    14401 gcggttaata agattgctga tttggtctct aatatgacca tccacttgat ggagaataca
    14461 gataaaggtg atatcagaat ccgtgatggg cttgctagaa agattgatat caatccgtgt
    14521 aaacacatga caaggaagtc atggattttc aagattgtgc gcgatttgct tttatatggc
    14581 gatgggaact ctgtcctaca tgtggaatat gaacctgtta cggattatat ttctaatcta
    14641 agaccatttc cgatgagaga ggtttcattc caaacagata aggattccta tgtaatctca
    14701 tttaggggtg aagaatattc ccctgatgaa gtagtccact tcgtcatcaa tccagatcca
    14761 gatattctat acattggtac tggttttagg gtgacgttga cagatgtggt tcaaagtttg
    14821 aacatggcta ccaagactaa aaaaagcttt atgaacggga agaatattcc tagtcttatc
    14881 gttaaagtag actcgtctag tgctgaacta gattcggagc aagggcgtga gcgtatcgct
    14941 gagaagtatt tgagtactag cagggttggc gctccatgga ttgttccaga ggcattgctg
    15001 gacattcagc aggtaaaacc gcttagtcta acggacatcg ctttaaacga gtctgtggaa
    15061 ttggataaaa gaacagttgc aggtctatta ggagtacctg cttttatttt gggtgtagga
    15121 gagttcaaca agacagagta taacaacttt gtaaatacga ctgtcatgag tattgctacc
    15181 actattactc aaacactaac cagggactta cttttgtcta gcaatcgtta cttcaagcta
    15241 aatcctcgtt cactcttctc ttacaacatt acggagttgt ctgctgttgc tcaacaaatg
    15301 gcaaacagtg ctgcaatgcg tcgtaatgag tggagggatt ggctagggat ggctcctgat
    15361 cctgagatgg aagagttgat tgttcttgaa aactttctcc ctcaggagaa actaggagat
    15421 caaaataaac tgaagggagg tgaggaagag aatgcaaaag cgaaatagct atcgtgccac
    15481 tcaatttcaa acgagagaag aagaatctgg agacttggtg ttgagtggct attttataaa
    15541 atttgatgaa gagacggagt tgtggcgtgg ttatcatgaa gtaatcaagc gtgctggtgt
    15601 tgagaaagct gtcacagacg ctgatatcag agctttattt aaccatgatg atagccttgt
    15661 tctcggtcga acaggtaacg gaactctgac actgggtgtt gatgatgttg gtctttttgg
    15721 agatatcatc attaacaagg atgatcctca agctgttggg gcctatgccc gtgtcaagcg
    15781 tggagatgtt atagggtgta gctttggctt tatcccggta aaaatcgaaa cggaagaacg
    15841 tgaagatggt tcgtatttgg acactgtctt agagctagaa atctttgaag tgagtccatg
    15901 tactttccca gcctatccac aaacggaaat tgctgcacga caaaaagact tcgaaagtca
    15961 gaagcgtgct aatcgtgaag cgctagacaa gcgcaagaaa gaaattaagg agaaatttaa
    16021 gctatgaata aggcattaat ctttggtgct cgtatgcgag caaaagcaac taaggtagtt
    16081 gagttggaag aaactatcga agaattgaac aaacgttcgg ttgttgagtt agaaaagttg
    16141 gatcgtgcta aaaatgatga agaagtttta gcagttgaaa agactgtaga cggtcttcaa
    16201 agggaaattg aagaaaaaga agctgaaaaa gtacagcttg aaaacgagat cgatgagtta
    16261 gataaacaaa tcaaagagca aaatcgtaaa gcaccaactc cggggaaaat ggaagaacga
    16321 ggaggaaaga cattgggaca acgtgaagca tttaatcatt acttacgaac aaaagaagcg
    16381 cgtgctgatg gtttcaaatc tgccgaaggg gaagcaatca ttcctgttga attgatgacg
    16441 cctaaagaag cgaaacaaga caagacagat ctgacttcat tggtcaacat cgttaatgtc
    16501 aagaacgcaa gcggtaaatg gtcagttgta aaattgactg atcaagcaat gaacactgtt
    16561 gaagagttgg aagaaaaccc tgaattggct aaaccaacct ttacaaaggt gaactatgaa
    16621 atcaaaacac gtcgtggtca tttgccagta tctcaagaat ttattgatga cgctgactac
    16681 gatgtcatgg gattggttgc taaacaaact aagaaccaag aacgtatcac taagaataaa
    16741 gagatcgcta aagttctcaa gacagctaca tctaaaagcg cagctggttt ggacggcttg
    16801 aaagatattc tcaacgtgga attgaaaaca tactacaatg caactatcgt atgtactcaa
    16861 tctatgttcg ctgctcttga taaaatcaag gacaaggacg gtcgctacat gctccaaaca
    16921 gatatcacat ctccaactgg ctacaagttt gctggtcgtg ttattgttgt ttatccagat
    16981 gatatcattg gagaaagcaa gggagatttg aaagccttca tcggtgacgt tggagaattt
    17041 gcgacattgt ttgaccgtgc gcagactact gtcaaatggc aagatgacaa aatctacggt
    17101 cagtatttgg caaccgctaa tcgttttgat gtagtaaaag tagacggaga tgcaggattt
    17161 tatgtgacct atacagatgc tgttttgtaa ggaggtagta aatggtatat aaggtaatcc
    17221 gtccttttaa ggacttacga gacccaaaga aacattgcta taaggttggg gataattacc
    17281 ctagagttaa gcacaaactt gataaagagt ttgcggagac tctgctaaat ggggcaaata
    17341 gtgcaggatc tatctttttg atgaatgtag aagataagga tatgtcgaaa gatgacacat
    17401 taactacaga agtagaaaag gaagaaacaa aggtagtaga tgggaaacct gaagagggag
    17461 acgaggagta gttatggaca atgttcaatt attagaattg cttaagctaa aattgggtat
    17521 agcaacaaaa ctacgcgata agcccttgga gaaaatcatc gaagctgtca aaacagaact
    17581 agaagataac ttaggagttc tacttgactt agacagctca gaagaccaaa tgtttgtagt
    17641 tgattttgca gcctttcgct atgagggtgg ggtggatatg ccacgtcacc ttcagtggcg
    17701 actgcataat ttacagatag catcaaagaa agaggtcaag aatgtggaat catgaaatca
    17761 cactgatctc taaggaagtc acaggtaagg ataaactact acaaccaatc tctgaagatg
    17821 ttgaagttac tctcctatgt cgcaaaaaga gggtcactcg ctctgaattt tatcaggcga
    17881 atcaggtagg gcttaaaccg agcttggtcg ttgagattcg aaattttgag tatgagaatc
    17941 aagagcttgc gaagttcgaa ggcaagcaat atcatatctt gaaaacctat cctattgatt
    18001 ctgaaatttt agagttgact ttgtcagagg tgttgaaatg agcttaacaa gtgatttagc
    18061 gaatgaaatt gcaaaggcaa tggcagagta ctctgctgag gtagaagata agattgacct
    18121 gattgctgag gacgttgtaa acgaagccgt tacggaatta aaagcgacta gtccaaaacg
    18181 tcatggaaag tatgctagaa attggcgctt caagaaaaat gctaaggggt catacgtcat
    18241 ctacaacgca gctccaacct atcgtttaac tcacttacta gaaaatgggc atgttttgag
    18301 aaatggcggt cgtagtcggg catttccaca tattaaacct gttgaggaga aagttaaaga
    18361 aaactttgag aagcgaatca aggagattgg gaaatgaagc tatcagactt tgctgctatt
    18421 ttggaacagg caaacttgcc tgtcacttat cgagcgttta aaattggaaa cgctcctaac
    18481 ctaccttatc tggtctatta tgaatcaatt ccagccatca atgcagctga caacacggtt
    18541 aatcatcaga ttaagagcgt gacagttgag ctggcttttg agagtaagga tgaagatttg
    18601 gaagaacgtc tggaagagct gtgggcaaac cacaagctct tttttgaagt tcaagaagaa
    18661 acatttatcg agactgaaag actctatgtc aagtcttaca cagtctatct atactaagga
    18721 ggaatgacat gactcaagaa aataaagtaa cctttggcct agaaaatgta catatcgcac
    18781 ctatcaagac acttgcagca gatggagtta tcacttacgg cgatgttttt cgttttcctg
    18841 gagcaataga tctgacactt gatactaaag gggaaacaac cactatcaaa gcagacaaca
    18901 aggattacca tttcatgaat tcaaacgaag gatatgaggg taaacttaaa atcccacaca
    18961 tcattgatga atttgcgaca aaaattcttg gtgaaatcaa ggaccctcaa actggtgtta
    19021 tgactgaaaa agcagatgcg agcttgacag agttcgcaat gatgttccag tttgaaggcg
    19081 acaaaaacaa gactcgctat gtgatgtact actgttttgc cagtcgccca tctcttggct
    19141 caaaaactaa gaacgggaca tcaaccaacg aacgtgaact tagtttcaaa gctagcccgc
    19201 gtccattgga tacagttgtc aagcgttcta tcacatcagc tgatgacaag gatgcgtatg
    19261 acaactggtt caagaaagtg tatgaaccta ctgcagttgc agcttaagga gaagatctat
    19321 gcgtaaaatc gttttggttg gtgatcagga gtatgagttg gggaccaacg gctatactcc
    19381 tattgcttac aagcaacaat ttggaaaaga ttattttcaa gatttgttct cgatgttgaa
    19441 aaatcaatca ttcatgaatg aattgaacaa gttggaaacc gacaaggaat tgacagcgac
    19501 taatattgat atttcgatgt tgtcagattt tgacatgacc tttttcaacc gtcttttttg
    19561 gacctttgct aaatctgaaa atcctcacat caagccttat gaacaattct tcatggaaat
    19621 ggaagtcttt ccgattcagg aagttgggcc tgtattgatg gaaatgctga atgcgagcat
    19681 gacgacaaaa aagcaccaga tgaatcagaa tcagctagcg aagaaatctt cacagtagaa
    19741 acctacttat cttgctgtaa agaaactggt ctttctattg atgatctaaa gcacatttca
    19801 atcggaatgg ctctggatta tcagacggat tatgtgaatc tacggagcga ggataagggt
    19861 ggcgaacgga aagccacgca agctgatttt gacggttttt aaagaaaaat gagtgctgag
    19921 agagcgattc tgagaccaag ttccttggtc tggctgcatt atcagtggta gaagttctct
    19981 cagcgctttt ctattttttt gagaaaggag gaaatatggc aggaaatatc aaaggtatta
    20041 aaattgaaat cgatggcgac acgcaaccct tacagaaggc gctgaaaaat gtcaataagg
    20101 ctgctactga tgcaagtcag gagttgagac agattgacaa agcattgaag tttgatacag
    20161 ggaacgtaac gctcctgact cagaagcaag aggtcttgca aaagcaagtt tcgacgacca
    20221 aagagaaact agaaaccttg agacaagctc agtctcaggt ggaacagcaa ttcaaaaatg
    20281 gcgatatcgg tgctgaccag taccgtgctt tccaacgtga agtagaagtt actcaaaacg
    20341 tcctaaaagg atatgagggt aagcttgcaa atgtgaatca ggcgcttaat gagaatggga
    20401 gtgctactca gaacaacaag aaccaattaa aagagttgca aaatgagcag agtcaacttg
    20461 cttcagagat gagtaaggtg acaagttcat tcaaactgca agaaagcgct ttgggttcaa
    20521 atgctagtga agccgagaga aatgctcttg ctcagaaaaa gattggtgct cagtctgaga
    20581 ttgtaagtaa acagatttca aatctagaac agcaattgga aatcactaaa aaagaatttg
    20641 gtgagaactc cacacaagcc aacaggatgg aagcagagct aaatcaggct aagacagcat
    20701 tcaatcatct caatgatgag atgaaaggaa caaagtctgc tgctgatagc actcaagaaa
    20761 gtttaagtga aatctcaaga aatttaagag cagaactact tcaacagttt agtgagaagt
    20821 tgagtgctat ttcagaaaag cttgtggaag taggaaaaga agcgttagaa gcagctgctc
    20881 aaatgcaagc tagtaatgct caatttacta ccgttttcgg agatatggaa acccaagcaa
    20941 gagaagcgtt gaatgctatt ggtcaggaaa tggatattgt cccagagcga ttgcaaggat
    21001 cattcactca gatggcttca tttgcaaaaa cttcaggatt ggatacagca gaagctttgg
    21061 atcttacttc tcgtgcaact agggcagcag cagacggtgc agccttctat gacaaatcta
    21121 ttgagagcgt gacagagagc ttacaatctt ttttgaaggg aaactttgct aacgatgcgg
    21181 ctcttggcat ttctgcaaca gaaacgacca ggaatgccgc tgcaaataaa ttgtacggaa
    21241 agtcattcaa ggacttgagc gaagcgcaga agcaattgac cttgcttcag atggtcgaag
    21301 acggaaataa actctcagga gctcttggac aggctgcaag agaatcagac ggcctggaaa
    21361 acgtgatggg gaatctgaaa caagctggga ccaatgcatt atctgctatt ggtcaacctc
    21421 ttctagaaat gatgattcct gtttttcaaa ccttggcaac gattgtgaaa ggtgtagctg
    21481 agctgttcag ttccttacct gctccagtaa aagattttgt tgttatttta ggaacagttg
    21541 tgactgctgt aggggtcata gcccccatat tcttatcgtt gcaagccctt gctgagtttt
    21601 taaaaatatc tattggagaa atgataattg ccgcattgcc aattattgga acagctattg
    21661 caattgctgc tgcagttgct gcaattattg ttattgtaaa atatctctgg gaaactaacg
    21721 aaggttttcg agatgcggtc acgaccgttt ggaatgcgat tcttgaagtt atcaatgcag
    21781 tcgtatcaga gatttctaat tttgtcatga gtatctttgg aacggttgtt gcttggtgga
    21841 cggagaacca ggaacttatt cgagcaagtg ctgagactgt ctggaatgct atctatacgg
    21901 ttataagcac aattctggaa attttaggtc cactcattca agctggttgg gataatatcc
    21961 aacttgtcat tacaacagct tgggaaatca ttaagactgt tgttgagact gcaataaacg
    22021 ttgtccttgg tatcattcaa gcagttatgc agatcatcaa tggtgattgg tcaggcgctt
    22081 gggaaactat taagggggta ttctctactg tatggcaagc tatccaaagc attgttcaga
    22141 ctattttctc agctatccag agttatattt caaatattct caacggcatt tcaggaactg
    22201 tatcaaatat ctggaacagc atcaaggaca ctgtctcaaa tgtgttaaat gctatatcta
    22261 gtactgtctc aagtgtttgg gaaggtatca agagtaccat ttcaagtgct atcaatggtg
    22321 caagggatgc tgtttcttca gctattgaag ccatcaaagg attgtttaac ttcaacatca
    22381 gctggccaca tatcccacta cctcactttt acgtgagtgg ttcggccaat ccattagatt
    22441 ggttgagtca aggtgttcca agtattggaa tcgaatggta tgccaaaggc ggtatcatga
    22501 cgaaaccaac tatctttgga atgaatggta ataacataat ggttggtggt gaagctggga
    22561 atgaagcagt attgccactt aacgacaaaa cgcttggagc catcggtcga ggtatcgctc
    22621 aaactatggg tggaacttca ccaaccatta acattaccat tactggcaac actgtcagag
    22681 aagaagccga catcagtcgt attgctgatg aggtggctca gcgtattgct gacgagttgc
    22741 aacgtaagac acaattgaga gcaggggtta catgataaag cataatgagc ttgtgattga
    22801 cggtgtgaga acatcgtctt ttccgtttaa agtcattgtc catgattctc cttcaattgc
    22861 tctgggagag agcaagacag ctcttttgga gcatggtggt atcagtgggg caattgttca
    22921 gacgaacaag cacagggaac tggtcaagaa atcttatacg atttacttag tcaaaccgac
    22981 tgaggagcag atgaaccaat ttatgagtct gtttatccgt gagaagttct ggttagagag
    23041 cgagcgagtc aaaacaactc gtctctggtg ctataaggtc aatgtgactg accttgaaga
    23101 agtacaacct ggtctttaca tgaccaaagc gaccttcact tgccatccta caaaatactt
    23161 caaagcaact gatactcaga gattgacaag aagcgggact ctgaatgtgc aaggttctgc
    23221 tcttgctttt cctaaaatca caatcgttgg tcagagcgtt gttgagactt catttacaat
    23281 cgctggtcag gtcattaggc ttgaaaaact ctcagaatcg cttgtgatgg ttaataatcc
    23341 tgacaatcct agctttaaaa cgacaacagg gaagccagtg aaatggtcag gggattttat
    23401 cacagttgat ccagcgaaag ttaagaatat tggggttgtt ttaggcccag gtattcaatc
    23461 gattgaaatc gaaacggttt gggggtgggc ataattgctt tatctactta ataaagatgt
    23521 aagaaccgtt cgatggaacg gggagccact tcatgaagcg acttcggcga ttgttaaaga
    23581 gatcatgaat ggtgatttca ccttaactgt gaaatatccc atttccgact ctggtattta
    23641 tcagctcatc caagaagata tgttgataaa agcgccgact cctgttcttg gtgcgcagct
    23701 atttcgcatt aagaaacctg ttgagcacaa tgaccatctg gaaatcacag cctatcacat
    23761 ttcagatgat gtgatgcaac gatctatcac acaaatgagt gtgactagtc agagttgtgg
    23821 catggctctt tctcgcatgg tacaaaacac caaaacagct cttggagact tctcattcaa
    23881 cagtgatatc caggaccgta ggacattcaa cacgactgag acagaaaccc tgtactctgt
    23941 attgctggac ggcaagcata gtatcgtcgg aacgtgggaa ggcgagctgg tgcgtgataa
    24001 ctttgcgatg actgtaaaga agagtcgtgg ggagaatcgt ggtgttgtta ttacaacgca
    24061 caaaaatctg aagaactacc aacgcacaaa aaacagtcag aatgttgtca caagaattca
    24121 cgcaaagtcg acttttaaac ctgaaggtgc tgaaaaggaa acaactatca gagtgactgt
    24181 tgatagtcct cttattaatt cttatcctta cataaacgaa aaagagtatg agaacaacaa
    24241 cgcaaaatcc gttgaagagt tgcagaagtg ggcacaggct aagttctcaa acgagggcat
    24301 tgacaagatc tctgacgcta tcaagattga agcttatgaa cttgatgggc aagttgttca
    24361 catgggtgat acggtcaatc tcaagagctg gaaacataat gttgatgtat ttaagaaagc
    24421 tattgcttat gagttcgatg ccttaaaaga agaatatatc tctctgattc tcgatgataa
    24481 ggcaggagct ggtggttcta gaacatctgg tggcttatct agcgcagcgg atgccattct
    24541 tggagtaaca gaatctgcac aagaagttgc ccttgaaaag gctcttcaaa atgctgactt
    24601 agactttgat cataaggctg gattgcttag acaggaaatt tctgacggca tcgaacttgc
    24661 caaggccaag gcggaagaag tcaagcaaga actgtctgac actatcaatc agcgctttaa
    24721 tagctttgac aacgggccat tgaaagaagc taagcgcagg gctgaagaag ccttgagaaa
    24781 cgctggcgca agcagcttac tcgctcagga agcgaagcgg attgggctgg attctgtcgc
    24841 tagacttgaa gagtttaagt cgcagactac gagcgcacaa acggctctgt caggtgactt
    24901 ggacgctctg aaacggacta tcgtgaatga tattcgaccg aagcaagcac aggttgaagc
    24961 tgagattgcc aagcaagttg aagcacttgt tcagaccaaa aaagaactgt ctggcgcaag
    25021 taccct
//
LOCUS       DAVLMQ010000026        24671 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000026 DAVLMQ010000000
VERSION     DAVLMQ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24671
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.026"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            143..508
                     /locus_tag="VXF95_001286"
     CDS             143..508
                     /locus_tag="VXF95_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HEV1081834.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            584..1525
                     /locus_tag="VXF95_001287"
     CDS             584..1525
                     /locus_tag="VXF95_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HEV1081835.1"
                     /translation="MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHGLSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            1473..2489
                     /locus_tag="VXF95_001288"
     CDS             1473..2489
                     /locus_tag="VXF95_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HEV1081836.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRAGLSQGKSFSEMMESLGCSSTIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
                     LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            2491..2817
                     /gene="comGC"
                     /locus_tag="VXF95_001289"
     CDS             2491..2817
                     /gene="comGC"
                     /locus_tag="VXF95_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HEV1081837.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQAKAYKEYHDKNGEA
                     NRKVND"
     gene            2810..3214
                     /locus_tag="VXF95_001290"
     CDS             2810..3214
                     /locus_tag="VXF95_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HEV1081838.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTLSNGSQKLTVPKGIQAPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            3219..3479
                     /locus_tag="VXF95_001291"
     CDS             3219..3479
                     /locus_tag="VXF95_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081839.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            3442..3903
                     /locus_tag="VXF95_001292"
     CDS             3442..3903
                     /locus_tag="VXF95_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1081840.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEKS"
     gene            3881..4294
                     /locus_tag="VXF95_001293"
     CDS             3881..4294
                     /locus_tag="VXF95_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HEV1081841.1"
                     /translation="MWKKKKVKAGVLLYAVTIAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEIATDSSEKVEKKKSEEKPEKKENS"
     gene            4431..5025
                     /locus_tag="VXF95_001294"
                     /pseudo
     CDS             4431..5025
                     /locus_tag="VXF95_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            5086..6039
                     /locus_tag="VXF95_001295"
     CDS             5086..6039
                     /locus_tag="VXF95_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1081842.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            6090..7280
                     /locus_tag="VXF95_001296"
     CDS             6090..7280
                     /locus_tag="VXF95_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HEV1081843.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGCSEQQILDIENHAQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKYIGQYLAVLNGADAIVFTAGVGE
                     NAENFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            7429..7800
                     /gene="rnpA"
                     /locus_tag="VXF95_001297"
     CDS             7429..7800
                     /gene="rnpA"
                     /locus_tag="VXF95_001297"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HEV1081844.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYQEGNGSEKETKVD"
     gene            7775..8599
                     /locus_tag="VXF95_001298"
     CDS             7775..8599
                     /locus_tag="VXF95_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HEV1081845.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTILIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            8618..9604
                     /locus_tag="VXF95_001299"
     CDS             8618..9604
                     /locus_tag="VXF95_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HEV1081846.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIETISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QAESQELEDLGLKVETNFDIEQVATEVMAYVQTIIDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNCYSRTFYITINVNDYVEHRAEVLQTYAQKL
                     AIRVLEEGRSHQTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            9655..10278
                     /locus_tag="VXF95_001300"
     CDS             9655..10278
                     /locus_tag="VXF95_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HEV1081847.1"
                     /translation="MLNKIRDYLDFSGLQYRSPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLEKQAKILDIPTVKGIYYLAYSDGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            10409..11866
                     /locus_tag="VXF95_001301"
     CDS             10409..11866
                     /locus_tag="VXF95_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1081848.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            11889..12170
                     /locus_tag="VXF95_001302"
     CDS             11889..12170
                     /locus_tag="VXF95_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1081849.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            12247..12732
                     /locus_tag="VXF95_001303"
     CDS             12247..12732
                     /locus_tag="VXF95_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1081850.1"
                     /translation="MNLKQALIDNDSIRLGLEANDWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            12749..13414
                     /locus_tag="VXF95_001304"
     CDS             12749..13414
                     /locus_tag="VXF95_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HEV1081851.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAVDPAGAARAFKDEIKR
                     IWG"
     gene            13418..14281
                     /locus_tag="VXF95_001305"
     CDS             13418..14281
                     /locus_tag="VXF95_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HEV1081852.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFIEMSIDERDERL
                     ARLDWSKEERLEVVKEIYETGVRIPSICFSGHRRYPLGSKDSVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIN
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAIQEAQAF
                     LYPLIKKAGLM"
     gene            14283..14987
                     /locus_tag="VXF95_001306"
     CDS             14283..14987
                     /locus_tag="VXF95_001306"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HEV1081853.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVAWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVEPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            15164..16837
                     /locus_tag="VXF95_001307"
     CDS             15164..16837
                     /locus_tag="VXF95_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1081854.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALVDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVTLQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINKEIVVQAFLEDI"
     gene            16949..18040
                     /gene="ulaG"
                     /locus_tag="VXF95_001308"
     CDS             16949..18040
                     /gene="ulaG"
                     /locus_tag="VXF95_001308"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HEV1081855.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            18154..20130
                     /gene="tkt"
                     /locus_tag="VXF95_001309"
     CDS             18154..20130
                     /gene="tkt"
                     /locus_tag="VXF95_001309"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1081856.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKIVRNLK"
     gene            20247..20546
                     /gene="yajC"
                     /locus_tag="VXF95_001310"
     CDS             20247..20546
                     /gene="yajC"
                     /locus_tag="VXF95_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1081857.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            20593..21021
                     /locus_tag="VXF95_001311"
     CDS             20593..21021
                     /locus_tag="VXF95_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HEV1081858.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQQYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            21023..21433
                     /locus_tag="VXF95_001312"
     CDS             21023..21433
                     /locus_tag="VXF95_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081859.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            21734..24385
                     /gene="adhE"
                     /locus_tag="VXF95_001313"
                     /gene_synonym="adhC"
     CDS             21734..24385
                     /gene="adhE"
                     /locus_tag="VXF95_001313"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HEV1081860.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGVATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT         7718 a         4428 c         5433 g         7092 t
ORIGIN      
        1 aatatttttg tacataagta aatagaaatt cagtcatcca tcagatggct ggatttttta
       61 tcaaaaaatt aagaaatgag catatttctt tccttgtctg gcggaattgg ttataatata
      121 cggtacaaag gaatgaatga atatgtatcg tgttatagaa atgtacggag attttgaacc
      181 gtggtggttc ttagaaggtt gggaagaaga tattgtagca agtagaaaat ttgaccagta
      241 ttatgatgct ctcaaatact acaaaacttg ctggtttaga ttggaacaag aatcccctct
      301 ttataaaagt agaagcgact tgatgaccat tttttgggac ccggaagacc aacgctggtg
      361 tgatgaatgt gatgagtatt tacaacaata ccattctttg gctcttttgc aggatgagca
      421 ggttatccca gacgaaaaac tacgctcagg ctatgaaaaa caaaccagtc aggaaaggaa
      481 tcgttcttgc cgtatgaaat taaaatagag aaaagtaact tttttggagt tgcttttttt
      541 atttttctaa cgctttgcga atagtatagg tgaggaggta agtatggttc aagaaattgc
      601 acaagaaatc attcgctcgg ctcggaaaaa aggggcgcaa gacatttatt ttgtccccaa
      661 gttagacgcc tatgagcttc atatgagggt aggagacgag cgctgtaaaa ttggtagcta
      721 tgattttgaa aagtttgcag ccgttatcag tcactttaag tttgtggcgg gtatgaatgt
      781 gggagaaaaa agacgtagtc aactgggttc ctgtgattat gcctatgacc agaagatggc
      841 gtctctacgt ttatctactg taggcgatta tcgggggcat gagagtttgg ttatccgttt
      901 gttgcacgat gaggagcagg acttgcattt ttggtttcag gatattgaag aattaggcaa
      961 gcagtacagg caacggggac tctatctttt tgctggtccg gttggaagtg gtaagacgac
     1021 cttgatgcat ggattgtcca agtcactctt taaaggacag caagttatgt ccatcgaaga
     1081 tcctgtcgaa atcaagcagg acgatatgct tcagttgcag ttgaacgaag caatcggcct
     1141 aacctatgaa aatctaatca aactttcctt gcgtcatcga ccagatctct tgattatcgg
     1201 agaaattcgt gacagcgaga cggcgcgtgc agtggtcaga gctagtttga caggtgcgac
     1261 agtcttttca accattcacg ccaagagtat ccgaggtgtt tatgagcgtc tgctggagtt
     1321 gggtgtgagt gaagaagaat tggcagttgt tctgcaagga gtctgctacc agagattaat
     1381 cgggggagga ggaatcgttg actttgcaaa cagagattat caagaacacc aagcagccaa
     1441 gtggaatgag caaattgacc agcttcttaa agatggacat atcacaagtc ttcaggctga
     1501 gacggaaaaa attagctaca gctaagcaaa aaaatatcat caccctattt aacaatctct
     1561 tttctagcgg ttttcatctg gtggagacta tctccttttt agataggagt gctttgttgg
     1621 acaagcagtg tgtgatccag atgcgtgcgg gcttgtctca agggaaatca ttctcagaaa
     1681 tgatggaaag tttgggatgt tcaagtacca ttgtcactca gttatcccta gccgaagttc
     1741 atggaaatct ccacctgagt ttgggaaaga tagaagaata tctggacaat ctggctaagg
     1801 tcaagaaaaa attaattgaa gtagcgacct atcctttgat tttgctgggt tttcttctct
     1861 taattatgct ggggctacgg aattacctgc tcccacaact ggatagtagc aatattgcca
     1921 cccaaattat cggtaatctg ccccaaattt ttctaggcat ggtagggctt gtttccgtgc
     1981 ttgccctttt agcactaact ttttataaaa gaagttctaa gatgagtgtc ttttctatct
     2041 tagcacgcct tccctttatt ggaatctttg tgcagaccta cttgacagcc tattatgcac
     2101 gtgaatgggg gaatatgatt tcacagggaa tggagctgac gcagattttt caaatgatgc
     2161 aggaacaagg ttcccagctc tttaaagaaa tcggtcaaga tctggctcaa accctgaaaa
     2221 atggccgtga attttctcag acgataggaa cctatccttt ctttaggaag gaattgagtc
     2281 tcatcataga gtatggggaa gttaagtcca agctgggtag tgagttggaa atctatgctg
     2341 aaaaaacttg ggaagccttt tttacccgag tcaaccgcac catgaatttg gtgcagccac
     2401 tggtttttat ctttgtggca ctgattatcg ttttacttta tgcggcaatg ctcatgccca
     2461 tgtatcaaaa tatggaggta aatttttaaa atgaaaaaaa tgatgacatt cttgaaaaaa
     2521 gctaaggtta aagcttttac attggtggaa atgttggtgg tcttgctgat tatcagcgtg
     2581 cttttcttgc tctttgtacc taatctgacc aagcaaaaag aagcagtcaa tgacaaagga
     2641 aaagcagctg ttgttaaggt ggtggaaagc caggcagaac tttatagctt ggaaaagaat
     2701 gaagatgcta gcctaagcaa gttaaaagac gatgggcgaa tcacggaaga acaggctaaa
     2761 gcttataaag aataccatga taaaaatgga gaagcaaatc gtaaagtcaa tgattaaggc
     2821 ctttaccatg ctggaaagtc tcttggtttt gggtcttgtg agtatccttg ccttgggctt
     2881 gtccggctct gttcagtcca cttttgcggc ggtagaggaa cagattttct ttatggagtt
     2941 tgaagaactc tatcgggaaa cccaaaaacg cagtgtagcc agtcagcaaa agactagtct
     3001 gaacttagat gggcagacgc ttagcaatgg cagtcaaaag ttgacagttc ctaaaggaat
     3061 tcaggcacca tcaggccaaa gtattacatt tgaccgagct gggggcaatt cgtccctggc
     3121 taaggttgaa tttcagacca gtaaaggagc gattcgctat caattatatc taggaaatgg
     3181 aaaaattaaa cgcattaagg aaacaaaaaa ttagggcagt gattttactg gaagcagtag
     3241 tcgctctagc tatctttgcc agcattgcga ccctcctttt gggacaaatt caaaaaaata
     3301 ggcaagagga agcaaaaatc ttgcaaaagg aagaagtctt gagggtagct aagatggccc
     3361 tgcagacggg gcaaaatcag gtaagcatca acggagttga gattcaggta ttttctagtg
     3421 aaaaaggatt ggaggtctac catggttcag aacagttgtt ggcaatcaaa gagccataag
     3481 gtcaaggctt ttaccttgtt agaatcccta cttgccctca ttgtcatcag tgggggatta
     3541 ctcctttttc aaactatgag tcagctcctc atttcagaag ttcgctacca gcaacaaagc
     3601 gagcaaaagg agtggctctt gtttgtggac caacttgagg cagaattaga ccgttcgcag
     3661 ttcgaaaaag tagaaggcaa tcgcctatac atgaagcaag atggcaagga catcgccatc
     3721 ggtaagtcaa agtcagacga ttttcgtaaa accgatgcta gtggacgggg gtatcagcct
     3781 atggtttatg gcctcaaatc agctcagatt acagaggaca atcaactggt tcattttcgt
     3841 ttccagtttc aaaaaggctt agaaagggag ttcatctatc gtgtggaaaa agaaaaaagt
     3901 taaggcaggt gttctcctct acgcagtcac catagcagcc atctttagtc ttttgttgca
     3961 attttacttg aaccgacaag tcgcccacta tcaagactat gctttgaata aagaaaaatt
     4021 ggttgctttt gcaatggcta aacgaaccaa ggataaagcc gagcaagaaa gtggggaaca
     4081 ggtctttaat ctaggtcagg taagctatca aaacaagaaa acaagcttgg tgacgactgt
     4141 tcgtacgtct aagagccaat atgagtttct gtttccttca gtcaaaatca aagaagagaa
     4201 aagagataaa aaggaagaga tagcgaccga ttcaagcgaa aaagtggaga agaaaaaatc
     4261 agaagagaag cctgaaaaga aagagaattc ctagtcaatt caactataat gcgttgaatc
     4321 cagaatagtc cactatagtt tctataaaat tgctggaaat ggatattaag ctccaattca
     4381 tttgtttata tcttatttca gtttactata ctttgtgcta aactaaagat atgaaacatg
     4441 attttaacca caaagcagaa actttcgatt cccctaaaaa tatcttcctc gcaaacttgg
     4501 tatgtcaagc agccgagaaa cagattgatc ttctatcaga caaagaaatt ttagatttcg
     4561 gtggtggcac gggtctatta gccttgcccc tagcccctag ccaagcaggc taagtcagtc
     4621 actcttgtag acatttctga gaaaatgttg gagcaagctc gtttgaaagt ggagcagcaa
     4681 gcaatcaaga atatccagtt tttggagcaa gatttaccga aaaatccctt ggagaaagag
     4741 tttgattgcc ttgctgttag tcgggttctt catcatatgc ctgatttgga tgcggctctc
     4801 tcactgtttc atcaacattt gaaggaagat gggaaactca tcattgctga ttttaccaag
     4861 acagaagcta atcatcatgg atttgattta gctgaactgg aaaacaagct aattgagcat
     4921 ggtttttcat ctgtgcatag tcagattctc tatagcgctg aagaccggtt tcaaggaaat
     4981 cactcagaat tctttttaat agtagcccaa aaatcactcg cctagtcagg gagtgatttt
     5041 tctataagga tggaaaaaag aagggaaatt tgataagata ggaatatgga ttttgaaaaa
     5101 attgaacaag cttataccta tttactagag aatgtccaag tcatccaaag tgatttggcg
     5161 accaactttt atgacgcctt ggtggagcaa aacagcatct atctggatgg tgaaactgag
     5221 ctaaaccagg tcaaagacaa caatcaggcc cttaagcgtt tagcactacg caaagaagaa
     5281 tggctcaaga cctaccagtt tctcttgatg aaggctgggc aaacagaacc cttgcaggcc
     5341 aatcaccagt ttacaccgga tgctattgct ttgcttttgg tgtttattgt ggaagagttg
     5401 tttaaagagg aggaaattac tatcctcgaa atgggttctg ggatgggaat tctaggcgct
     5461 actttcttga cctcgcttga taaaaaggtg gattacttgg gaatggaagt ggatgattta
     5521 ctgattgatc tggcagctag catggcagat gtaattggtt tgcaggctgg ctttgtccaa
     5581 ggagatgccg ttcgtccaca aatgctcaaa gaaagcgatg tggtcatcag tgacttgcct
     5641 gttggctatt atcctgatga tgccgttgcg tcgcgccatc aagttgcttc tagccaagaa
     5701 catacttacg cccatcactt gctcatggaa caagggctta agtacctcaa gtcagacgga
     5761 tacgctattt ttctagctcc gagtgatttg ttgaccagtc ctcaaagtga tttgttaaaa
     5821 gaatggctga aagaagaggc gagtctggtt gctatgatta gtctgcctga aaacctcttt
     5881 gctaatgcca aacaatctaa gactattttt atcttacaga agaaaaatga aatagcagta
     5941 gagccttttg tttatccact tgctagcttg caagatgcaa gtgttttaat gaaatttaaa
     6001 gaaaattttc aaaaatggac tcaaggtact gaaatataaa atagattttg ttataatagt
     6061 tgaaaacgct taaaaagggg tatcatgtta tgacaaaaac aattgcaatc aatgcaggaa
     6121 gttcaagttt gaaatggcaa ttatacttaa tgccagaaga aaaagtattg gcgaaaggtt
     6181 tgattgaacg tatcggtttg aaagattcaa tttcaactgt aaaatttgac ggctgttctg
     6241 aacaacaaat tttggatatt gaaaatcatg cacaagccgt taaaatttta ttggatgact
     6301 tgattcgttt cgatattatc aaggcttatg acgagattac aggtgttgga catcgtgttg
     6361 ttgctggtgg agaatatttc aaagaatcaa cagttgttga gggagatgtt ttagaaaaag
     6421 ttgaagagtt gagtttgttg gctcctctac acaacccggc caatgcagca ggtgttcgtg
     6481 ccttcaagga attgttgcca gacattacca gtgtagttgt ttttgatact tccttccaca
     6541 caagtatgcc agagaaagct tatcgctacc ctctaccaac aaaatattac acagaaaaca
     6601 aggttcgtaa atacggtgct catggtacaa gtcaccagtt tgtagcagga gaggctgcaa
     6661 aactcttggg acgtccatta gaagacttga agttaattac ctgtcatatt ggtaacggag
     6721 gctcaattac agctgtgaaa gccggcaaat ctgtagacac ttctatgggg ttcactcctc
     6781 ttggtggtat tatgatggga acgcgtacag gggatattga tccagctatc attccttatt
     6841 taatgcaata tacagaggat tttaacacac cagaagatat cagtcgtgtt cttaaccgtg
     6901 aatcaggtct tttgggagtt tctgctaatt ctagcgatat gcgcgatata gaagcagctg
     6961 tagcagaagg gaatcacgag gctagcttgg cttatgaaat gtatgttgac cgtatccaaa
     7021 aatatatcgg tcagtacctt gcagtgctaa atggagcaga tgccattgtt ttcacagcag
     7081 gtgtcggtga aaatgcagag aatttccgtc gtgatgtaat ctcagggatt tcgtggtttg
     7141 gttgtgatgt tgatgatgaa aagaatgtct ttggcgttac aggagacatc tcaacagagg
     7201 cagctaaaat ccgtgtcttg gttattccaa cagatgaaga attagtcatt gcccgtgacg
     7261 ttgaacgctt gaaaaaataa gtgaaactaa aaaaatattc aatacaagga gttgggaaag
     7321 ttatttttcc agcttctttt tctgatgaaa ttgtccaaaa ccttgctatg attggctttt
     7381 ttgaaaaata tggtataata gtagtaattt aatagatgga gttgagtttt gaagaaaaac
     7441 tttcgtgtaa aaagagagaa agattttaag gcgattttca aggaggggac aagttttgct
     7501 aatcgcaaat ttgtggtcta ccaattagaa aaccagaaaa accattttcg agtaggtcta
     7561 tcagttagca aaaaactggg gaatgccgtc actagaaatc aaattaagcg acggattcgg
     7621 catattatcc agaatgcaaa agggagtctg gtagaagatg tcgactttgt tgtcattgct
     7681 cgaaaaggag tcgaaacctt gggatacgca gagatggaga aaaatctact ccacgtatta
     7741 aaattatcaa agatttacca ggaaggaaat gggagtgaaa aagaaactaa agttgactag
     7801 tttgctagga ctgtctctgt taatcatgac agcctgtgcg actaatgggg taactagcga
     7861 tattacagcc gaatcggctg atttttggag taaattggtt tacttctttg cggaaatcat
     7921 tcgcttttta tcgtttgata ttagtatcgg agtggggatt attctcttta cgatcttgat
     7981 tcgtacagtc ctcttgccag tctttcaggt gcaaatggtg gcttctagga aaatgcagga
     8041 agctcagcca cgcattaagg cgcttcgaga acaatatcca ggtcgagata tggaaagcag
     8101 aaccaaacta gagcaggaaa tgcgtaaagt atttaaagaa atgggtgtca gacagtcaga
     8161 ctctctttgg ccgattttga ttcagatgcc ggttattttg gccctgttcc aagccctatc
     8221 aagagttgac tttttaaaga caggtcattt cttatggatt aaccttggta gtgtggatac
     8281 aacccttgtt cttccgattt tagcagcagt attcaccttt ttaagtactt ggttgtccaa
     8341 caaagctttg tctgagcgaa atggcgctac gactgcgatg atgtatggga ttccagtctt
     8401 gatttttatc tttgcagttt atgcgccagg tggagtcgcc ctatactgga cagtgtctaa
     8461 tgcttatcaa gtcttgcaaa cctatttctt gaataatcca ttcaagatta tcgcagagcg
     8521 cgaggccgta gtacaggcac aaaaagattt ggaaaataga aaaagaaaag ccaagaaaaa
     8581 ggctcagaaa acgaaataaa taaggaggaa tctggtaatg gtagtattta caggttcaac
     8641 tgttgaagaa gcaatccaga aaggattgaa agaattagat attccaagaa tgaaggctca
     8701 tatcaaagtc atttctaggg agaagaaagg ctttcttggt ctatttggta aaaaaccagc
     8761 ccaagtggat attgaaacga ttagtgaaac gactgttgtc aaagcaaatc aacaggtagt
     8821 aaaaggcgtt ccgaaaaaaa tcaatgattt gaacgagcct gtgaagacgg ttagtgaaga
     8881 aaccgttgac cttggtcatg tggttgatgc tattaaaaaa atagaggaag aaggtcaagg
     8941 catttctgat gaagtcaagg ctgaaatctt aaaacatgaa agacatgcca gcactatctt
     9001 agaagaaact ggtcacattg agattttaaa tgaacttcaa atcgaggaag cgatgaggga
     9061 agaagcaggc gctgatgacc ttgaaactga gcaagaccaa gctgaaagtc aagaactaga
     9121 agacttgggc ttgaaagttg aaacgaactt tgatattgaa caagtagcta cggaagtaat
     9181 ggcttatgtt caaacgatta ttgatgacat ggatgttgag gctacacttt caaatgatta
     9241 taaccgtcgt agcatcaatt tgcaaattga tactaacgaa ccaggtcgta ttatcggcta
     9301 ccatggtaaa gtcttgaagg ccttgcaact gttggctcaa aattatcttt acaactgcta
     9361 ttcaagaacc ttctatatca ctattaatgt caatgattat gttgaacacc gtgcagaagt
     9421 cttgcagacc tatgcgcaaa aattggcgat tcgtgtttta gaagaaggac gtagtcatca
     9481 aacagatcca atgtcgaata gtgaacgcaa gattatccac cgtattattt cacgtatgga
     9541 tggcgtgacc agttactctg aaggtgatga gccaaatcgc tatgtcgttg tagatacaga
     9601 ataagtaaaa tcagggttga cctgattttt tgctagctag aggaggttaa actgatgttg
     9661 aataagataa gagactatct agacttttct ggtttgcagt accgtagtcc tgataaagcg
     9721 ggggcagagc gagagaagat gctggcgttc cgccacaaag gacaagaggc ccgaaaggct
     9781 tttacagaac tggccaaagc ctttcaagca agccatccag aatggcaact ccaacagact
     9841 agtcagtgga tgaatcaggc ccagcgtttg agaccacatt tttgggttta tctacagaga
     9901 gacggacaag tgacagaacc tatgatggcc ttacgtttgt atgggacatc tactgacttt
     9961 ggaatttctt tggaagtcag tttcatcgaa cgtaagaagg atgagcaaac tttagagaaa
    10021 caggccaaga ttttagacat accaaccgtt aaaggaattt attatctagc ctactctgat
    10081 ggccaaagtc aacggtggga ggcgaacgaa gaaaagcgtc gtactttacg cgagaaggtg
    10141 agaagtcaag aagttcgaaa agttttagtg aaggtagatg ttcctatgac agaaaattcg
    10201 tctgaagaag aaatcgtaga aggcttattg aagtcttatt ctaaaattct tccctattat
    10261 ctagctacga gaaaataaga taatttgtaa aacatcataa atcatacagt ccaagagtga
    10321 acagtccgct gtgtaattct tggtcttttt gtttgcgctt tcgcattata taataaactt
    10381 acaaaaacaa ttcaaaagga gaacaattat ggaagtcgtt tcaagtgttc taaattggtt
    10441 ttctagcaat attttgcaga atcccgcatt tttcgtaggt ttattggtgt tgataggata
    10501 tgcacttttg aaaaaacctg cccatgacgt tttttcaggg tttgttaaag caacagtagg
    10561 gtatatgttg cttaacgtgg gtgctggtgg tttggttaca acctttcgtc caatcttagc
    10621 agctcttaac tacaaattcc aaattggtgc agcggttatc gacccttact ttggacttgc
    10681 tgcagcaaac aacaaaattg cagcagagtt tccagatttt gttggaactg caactacagc
    10741 tctattgatt ggttttggaa taaatatctt gctcgtagct cttcgaaaga ttacgaaggt
    10801 aagaaccctc tttattactg gtcacatcat ggtacaacaa gctgcaacag tatctcttat
    10861 ggttctattc ttagtaccac aattgcgcaa tgcttacggt acagcagcga ttggtatcat
    10921 ctgtggactt tactgggcag ttagttcaaa tatgactgtt gaggcaactc aacgcttgac
    10981 tggtggtggc ggatttgcga ttggtcacca acagcaattt gcaatctggt ttgtagataa
    11041 agtagcagga cgctttggta agaaagaaga aagtttagac aatcttaaat tacctaagtt
    11101 cctctcaatc ttccacgata cagttgttgc atctgctacc ttgatgctcg tattcttcgg
    11161 ggccattctt ttaatcttgg gtccagacat tatgtctaat aaagaagtca tcacttcagg
    11221 aactctattc aatcctgcta aacaagattt ctttatgtac attatccaaa cagcctttac
    11281 cttctcagtt tacttgttcg ttttgatgca aggtgtccga atgttcgtat ctgagttaac
    11341 aaacgctttc caaggtattt caaacaaatt gttgccaggt tcattcccag cggttgacgt
    11401 tgcagcttct tatggatttg gttctccaaa tgctgtcttg tcaggattta cctttggttt
    11461 gattggtcaa ttgattacaa ttgtcttgct catcgtcttt aaaaatccga ttcttattat
    11521 tacaggattt gtaccagtgt tctttgacaa tgcagccatt gcggtctacg ctgataaacg
    11581 cggcggatgg aaagcggctg ttatcctttc ctttatatca ggtgtccttc aagttgctct
    11641 aggagctctt tgtgtggccc ttctcgattt ggcatcttat ggtggctacc atggaaatat
    11701 cgactttgaa ttcccatggc ttggatttgg atatatcttc aaataccttg gtattgttgg
    11761 ttatgtactt gtgtgtctct tcttgcttgt tattcctcaa cttcaatttg ccaaagcaaa
    11821 agataaagag aaatattaca acggtgaagt tcaagaagaa gcttagtatc tagaaaagga
    11881 gaaataaaat ggttaaagta ttagcagcgt gcggaaatgg aatgggttca tcaatggtta
    11941 tcaagatgaa ggttgaaaat gctctccgta agcttaatca aacagatttt acagtcaatt
    12001 catgcagtgt cggtgaagct aaaggtttag cagtaggata tgacatcgta atcgcttctc
    12061 ttcatttgat tcaagaattg gaagggcgaa ctaatgggaa gttaattgga cttgataact
    12121 tgatggatga taaagaaatc accgaaaaac tcagtcaagc actacagtaa aaggttggag
    12181 ggggctggac agaaactgag agttatcgtt tctgtccttc tccctcttta aataaaggag
    12241 gcagatatga atttaaaaca agctttaatt gacaatgact cgatccgact aggtttagag
    12301 gctaacgatt ggaaagaagc agtcaaggta gcagtagatc ccttgattga aagtggggca
    12361 attttgccag agtattacga tgctatcatt gaatcgactg aagagtatgg gccttactat
    12421 atcttgatgc caggtatggc tatgccccac gctagacctg aagctggtgt gcaaagtgat
    12481 gccttttcat taattacctt acaaaatcct gttgtatttt cagatgggaa agaggtatct
    12541 gttttgttgg cactagcagc aacaagttca aaaattcaca caagtgtagc cattccacaa
    12601 attattgccc tgtttgaatt agaagattct attgcacgtt tacaggcttg ccagactaaa
    12661 gaagatgtct tggctatgat tgaagaatct aaggatagcc cttatctcga aggattggat
    12721 ttggaaagtt agaaagagga ataaagaaat gacaaaaaga atacctaatt tacaagttgc
    12781 attagaccat tcagacttgc aaggagcgat taaagcagct gtttctgttg gtcaggaagt
    12841 agatattatc gaagctggaa ctgtttgctt gcttcaagtt ggaagtgaac tggctgaagt
    12901 cttgcgtagc cttttcccag ataagattat tgtggcagac acaaaatgtg ctgatgctgg
    12961 tggaacagtt gctaaaaata atgcggttcg tggagcagac tggatgactt gtatctgttg
    13021 tgcaaccatc cctactatgg aagcagctct aaaggctatc aagactgaac gaggagaacg
    13081 aggcgaaatc cagatcgagc tttatggcga ttggactttt gaacaagctc agctttggct
    13141 agatgcaggt atctcacaag ctatttatca ccaatctcgt gatgctcttc ttgctggtga
    13201 aacttggggt gaaaaagacc ttaataaggt taaaaaactc attgacatgg gcttccgtgt
    13261 atctgtaaca ggtggtctag atgtagatac tctcaaactc tttgaaggtg ttgatgtctt
    13321 tacctttatc gcaggtcgtg gaattacaga ggctgtggat ccagcaggag cagcgcgtgc
    13381 cttcaaggat gaaatcaaac gaatttgggg gtaaatcatg gtacgtccaa ttggaattta
    13441 tgaaaaggca accccaacac actttacttg gctagaacgt ttaaattttg ccaaggagtt
    13501 aggctttgat tttatcgaga tgtctattga cgaacgtgac gagcgtttag caagacttga
    13561 ctggagtaag gaagaacgct tggaagttgt caaagaaatc tatgaaactg gtgttcgtat
    13621 tccttctatc tgtttttcag gccatcgtcg ctacccattg ggatcaaaag attcagttct
    13681 agaggaaaaa tctctagaac tcatgaaaaa atgtatcgaa ttagctcaag acttgggagt
    13741 tcgtacgatt caattagctg gttacgatgt ttactatgag gaaaagtcac cccagacacg
    13801 ccaacgtttt atcaaaaatt tgagaaaagc ctgtgactgg gctgaagaag ctcaggtggt
    13861 acttgctatt gaaattatgg atgatccttt catcaatagc atcgaaaaat atttggctat
    13921 agaaaaagag attgactctc ccttcctctt tgtatatcca gatattggta atgtgtctgc
    13981 atggcataat gatatctata gtgagtttta tcttggtcat catgccatcg cagctctcca
    14041 tctcaaggat acttatgcag tgacagaaag ttcaaagggc cagttccgag atgtaccttt
    14101 tgggcaaggt tgtgtcaaat gggaagaagc tttcgatatt ttaaaggaaa ccaattataa
    14161 tggacctttc ctaatcgaaa tgtggtctga aaattgtgaa acagtagaag aaacacgcgc
    14221 agccattcaa gaggcgcaag cttttctcta tccactcatt aagaaagcag gtttgatgta
    14281 agatgaatca agtaatcaat gctatgcgta aacgagtctg tgatgccaat caatcattgc
    14341 caaaacatgg acttgtcaaa tttacctggg ggaatgtatc tgaagtcaat cgcgaactcg
    14401 gtgtcattgt tatcaaacca tcaggcgtgg attatgacga attgacacct gaaaacatgg
    14461 tagtgactga tctagatggt aagatcctag aaggggattt aagaccatct tccgacctcc
    14521 caactcatgt gcaattatat aaggcttggt cagaaattgg tagtgtggtt cacacccatt
    14581 cgacagaagc tgttgcttgg gctcaggcag gtcgtgatat tcctttctac ggaacaaccc
    14641 atgcagatta tttctacggt tcaatccctt gcgcccgtag tttgaccaag gacgaagtag
    14701 aagtggccta tgaaaaagat actggcctgg ttatcgtaga agagtttgaa catcgcggac
    14761 ttaacccggt tgaagtacca ggaattgttg tacgcaatca cggtccattc acctggggca
    14821 aaaatccaga gaatgctgtt tatcactctg tcgtactaga ggaagtatca aagatgaatc
    14881 gctttacaga acaaatcaat ccaagagttg aacctgctcc ccagtacata ctagaaaaac
    14941 actaccaacg taaacatgga ccaaatgctt attatggtca aaagtaagaa cgatgaagga
    15001 ggagaaaaag ataaatttag ctcctctttt tacatttgat ttttattgag agtaaagttg
    15061 gagttgaagt aattttgaaa gattttttag aaatagcgct tgatatatat ggtaaaataa
    15121 aaagaattgc tgtgatatca atagatttgg gggatttttt aatatggtac tggataaggc
    15181 aagttgtgat ttgcttcaat atttgatgga tcaagaaacg tccaaaacga ttatggcgat
    15241 ttcgaaagat ttgaaagagt caagaaggaa aatttattat cacattgaca aaatcaatgc
    15301 tgctctggtt gacgaggcgc ttcacatcat tagtattcca cgaattggta ttcacttaac
    15361 ggaagagcag agagatgctt gttgtaaact attatcggaa gtagattcgt acgattatat
    15421 catgagtgcg catgaacgta tgatgataat gttactatgg ataggtattt ctaaagaacg
    15481 tattacgatt gaaaaattga tagagttaac agaggtatct aggaatactg ttctcaatga
    15541 tttgaatagt attcgttatc aactaacttt ggaacaatat caggtgacct tgcaagtgag
    15601 caagtcacag ggataccacc ttcatgccca ccctcttaat aaaattcagt atcttcaatc
    15661 gcttctatat catattttta tggaagaaaa tgccactttt gtatctattt tagaagataa
    15721 gatgaaagag aggttagatg atgagtgttt gctttctgtt gaaatgaacc aattttttaa
    15781 ggaacaggtt cctttagttg aacaagattt agggaagaaa ataaaccatc atgaaataac
    15841 ttttatgttg caggttctac cttatttgct gttaagctgt cataatgttg aacagtatca
    15901 agaaagacat caggatatag agaaagaatt ttctttgata agaaaaagaa tagagtatca
    15961 ggtgtctaag aaattaggag aacggttgtt tcaaaagttt gaaatttctt tgtcaggact
    16021 tgaagtttct cttgtagctg ttctcctcct ctcctatcgt aaagatttgg atattcatgc
    16081 agaaagtgat gattttcggc aattaaaact tgctttagaa gaatttatct ggtattttga
    16141 atcacaaatc cgaatggaga ttgagaacaa ggatgatttg ttacgaaatt tgatgatcca
    16201 ctgtaaagcc ttgttattta gaaagactta cggtattttt tctaaaaatc ctctaacaaa
    16261 acaaattcga tccaagtatg gagaattatt tttagtcact agaaaatctg cggaaatttt
    16321 agaaggagca tggtttattc ggctaacaga cgatgatatt gcctatttga cgattcatat
    16381 tggaggattt ttaaagtata caccatcgtc tcaaaaaaat atgaaaaaag tttatctcgt
    16441 ttgtgatgaa ggtgttgcgg tttcgagact tttgctgaaa caatgcaaac tttattttcc
    16501 aaatgagcaa attgacactg tatttacaac agaacaattt aagagtgtgg aagatattgc
    16561 acaagttgat gtagtgatta ctactaatga tgatttggat agcagatttc cgattttaag
    16621 ggttaatcct atccttgaag cagaagatat tttgaaaatg ctagactatc ttaaacacaa
    16681 tatatttcgt aataagagca aaagtttcag tgaaaatctt tctagtctta tttcgtctta
    16741 tattgtagac agcaagttgg ctagtaagtt ccaagaagag gttcaaacac ttataaataa
    16801 agaaatagta gttcaagctt ttttggaaga tatttgaagg acagtccaat gatgaacaca
    16861 aacctgtgtt tttcttggtc ttttttagtg ttttgaaggg tggtatacta atctcaaaga
    16921 taacaattat atccaaagga ggcaacatat gccaaacgtc aaagaaatta caagagagtc
    16981 atggatttta gccactttcc cagagtgggg aacatggttg aacgaagaaa tcgaagaaga
    17041 agtcgtacct gaaggcaact ttgccatgtg gtggctaggc aactgtggta cttggattaa
    17101 gacaccagct ggtgctaacg ttgtcatgga cctttggtca aaccgtggaa aatcaaccaa
    17161 aaaagtgaaa gatatggttc gtgggcacca aatggcaaat atggcaggtg ttcgtaagtt
    17221 gcaaccaaac ttgcgtgttc agccaatggt tatcgatcca tttgctatca acgaactaga
    17281 ctattactta gtttcacact tccacagtga tcatatcgac ccatacacag ctgcagcaat
    17341 tctcaacaat cctaagttag agcatgttaa gtttatcggt ccttaccact gtggacgaat
    17401 ctgggaagga tggggtgttc caaaagaacg tatcatcgtt gttaaaccag gtgacactat
    17461 cgaattaaaa gatatgaaga ttcatgcagt agaatcattt gaccgtactt gcttggtaac
    17521 tctcccagtg aacggtgctg atgagacagg cggtgaactt gctggcttgg ctgttacaga
    17581 tgaagaaatg gctcaaaagg ctgttaacta tatctttgaa acaccaggtg gaaccatcta
    17641 tcatggtgca gattctcact tctcaaacta ttttgcaaaa catggtaaag actttaaaat
    17701 tgatgttgct ttgaataact atggtgaaaa tccggtaggt atccaagaca aaatgacatc
    17761 tatcgacctt cttcgtatgg cagaaaatct gcgtaccaaa gtcattatcc cagttcacta
    17821 tgatatctgg tctaacttca tggcttctac taatgagatt ctagaacttt ggaaaatgcg
    17881 aaaagatcgc ttgcaatacg atttccatcc atttatctgg gaagttggcg gtaagtacac
    17941 ttatcctcaa gatcaacact tagtagaata ccatcatcca cgtggttttg atgattgttt
    18001 tgaacaagac tctaacattc aatttaaagc tttgctataa tataaaaata ttctttggag
    18061 gttatccgta tgttgcatga tacggataat tttcatataa tagtaaaata gaatgtgtga
    18121 ttcaataatc acctcaaata gaaaggaaat tctatgtcaa atctatctgt taatgcaatt
    18181 cgttttctag gtattgacgc cattaataaa gccaactcag gtcatccagg tgtggttatg
    18241 ggagcggctc cgatggctta cagcctcttt acaaaacaac ttcatatcaa tccagctcaa
    18301 ccaaactgga ttaaccgcga ccgctttatt ctttcagcag gtcatggctc aatgctcctt
    18361 tatgctcttc ttcacctttc tggttttgaa gatgtcagca tggatgagat taagagcttc
    18421 cgtcaatggg gttcaaaaac accaggtcac ccagaatttg gtcatacggc agggattgat
    18481 gctacgacag gtcctctagg gcaagggatt tcaactgcta ctggttttgc ccaagcagaa
    18541 cgtttcttgg cagccaaata taaccgtgaa ggctacaata tctttgacca ctatacttac
    18601 gttatctgtg gagacggaga cttgatggaa ggtgtctcaa gcgaggcagc ttcatacgca
    18661 ggcttgcaaa aacttgataa gttggttgtt ctttatgatt caaatgatat caacttggat
    18721 ggtgagacaa aggattcctt tacagaaagt gttcgtgacc gttacaatgc ctacggttgg
    18781 catactgcct tggttgaaaa tggaacagac ttggaagcca tccatgctgc tatcgaaaca
    18841 gcaaaagctt caggcaagcc atctttgatt gaagtgaaga cggttattgg atacggttct
    18901 ccaaacaaac aaggaactaa tgctgtacac ggcgcccctc ttggagcaga tgaaactgca
    18961 tcaactcgcc aagccctcgg ttgggactac gaaccatttg aaattccaga acaagtatat
    19021 gctgatttca aagaacatgt tgcagaccgt ggcgcatcag cttatcaagc ttggactaaa
    19081 ttagttgcag attataaaga agctcatcca gaactggctg cagaagtaga ggccatcatc
    19141 gacggacgtg atccagtcga agtgactcca gcagacttcc cagctttaga aaatggtttt
    19201 tctcaagcaa ctcgtaattc aagtcaagat gccttgaatg ttgtggcagc taaattacca
    19261 accttcctag gtggatcagc tgaccttgct cactcaaaca tgacttatat caagacggat
    19321 ggacttcaag acgataccaa tcgcttgaat cgtaacattc agtttggtgt tcgtgaattt
    19381 gcaatgggaa caatcttgaa cgggatggcc cttcatggtg gacttcgtgt atacggtgga
    19441 actttcttcg tcttctctga ctatgtgaag gcagctgtcc gcttgtcagc cttacaagga
    19501 cttcctgtga cttatgtctt tacccatgat tcaatcgcag ttggggaaga tggtccgact
    19561 cacgaaccag ttgagcattt agcaggtctt cgtgctatgc caaatctaaa tgttttccgt
    19621 ccagcagatg cgcgtgaaac tcaagcagct tggtaccttg cagtgacaag tgagaaaaca
    19681 ccaactgccc ttgtcttgac acgtcaaaac ttgactgttg aagatggaac agacttcgac
    19741 aaggttgcta aaggtgctta tgttgtatat gaaaatgcag ccgactttga taccatcttg
    19801 attgcgacag gttcagaggt taatcttgct gtctcagctg ctaaagaatt ggctagtcaa
    19861 ggcgaaaaaa tccgcgtagt cagcatgcca tctacagatg tctttgataa acaagatgca
    19921 gcttacaagg aagaaattct tccaaatgca gtccgccgtc gtgttgcagt cgaaatgggt
    19981 gcaagtcaaa actggtacaa atatgttggt ctcgatggtg ccgttctagg tattgatacc
    20041 ttcggagcct ctgccccagc accaaaagta ttggcagaat atggctttac tgtagaaaat
    20101 cttgtaaaaa ttgttcgaaa cttgaaataa tcctaaaaat cagggcgtaa gctctggttt
    20161 ttcttaccag aaaagtaagg tacaatcttg taaaagtagc tgaaatttga tatagtagtc
    20221 ctatgtaaaa gacaaaggag aaaacaatga atccaaatat tactttttta atcatgcttg
    20281 taggtatgat ggccttgatg ttctttatgc aacgttctca aaagaaacaa gctcaaaagc
    20341 gtatggaaag cttaaataaa ctacaaaaag gctatgaagt gattacaatc ggtggacttt
    20401 atggaacagt cgatgaagta gatacggaga agggaacaat agttcttgac gtagatggag
    20461 tttacttgac ttttgaacta gctgctatca agacagtatt accgctgaaa gaaacagctt
    20521 cactagaagg cgcaattgaa aaataagacg ggatcacgaa ctcccgtttt tctataaaag
    20581 aaaggaaatg ggatgaaaaa attagtcttt gtctgtctgg gaaatatttg ccgtagccct
    20641 atggccgagt ttgttatgaa atcaatgaca gataactacg aaatccaaag tcgagcaact
    20701 tcctcttggg aacatggcaa tccgattcat aaggggactc agggaatttt tcaacagtat
    20761 gagattcctt atgacaagaa caagacatcg cttcagatta gtaaggaaga ttttgaagcc
    20821 tttgattata ttatcggaat ggacgcttca aatatttctg acttacgtca gatgtgtcca
    20881 gtagactgtc aagataagat ttactcattt tcatctgaaa gtgttccaga cccttggtat
    20941 acaggagatt ttgaagaaac ctatcgacgt gttcaagagg gctgtcaagc ttggttagaa
    21001 cgtttagaaa aggagagtta aggtggaaaa tcttacgaat ttttacgaaa agtatcgtgt
    21061 ctatctgact cgtccacgtt tagagctttt ggcagtagtt accattgttt tctgtgctgt
    21121 actcgtcttt tttctaaata ttccaggaaa aggtgtctta aaactcgata atggaacgat
    21181 tgtttatgat ggcagtcttg tccgtggtaa aatgaatggt caaggtacca ttaccttcca
    21241 aaatggagac caatatacag gtggcttcaa caatggagcc ttcaacggaa aaggtacctt
    21301 tcaatctaaa gaaggctgga cctacgaagg tgattttgta aatggtcagg ctgaaggaaa
    21361 agggaaacta acaacagaac aagaagtcgt ttatgaagga acttttaaac aaggcgtttt
    21421 tcaacaaaaa taaagcctcc ttatccaaag gaggtattat tagaaccaca aggtaagcgc
    21481 ttacctgtaa atccctttct ttccaaatcc ctcttccaag caagtttgtg aaataaaaaa
    21541 tatttgaaat aaatttcaca aacttcaaag ataaaacctg ataagaaaag aaaatgagaa
    21601 aagtttcaca agagtttaaa aattctttgt gaaatgttta tgaaactgtt tacaaagttg
    21661 aaataatgcg ttataataaa cttgtgaaaa aattaacaaa ggatatcgtt ccttgaaagc
    21721 tatggaggaa aatatggctg ataaaaaaac tgtgacacca gaggaaaaga aactcgttgc
    21781 tgaaaaacac gtagatgagt tggttcaaaa agctctagtt gcccttgaag aaatgcgtaa
    21841 attggatcaa gagcaagttg actacatcgt tgccaaagca tcagtagcag ctttggatgc
    21901 ccacggagaa ttggctttac atgcctttga agaaacagga cgtggtgtat ttgaagacaa
    21961 agcaactaag aacttgtttg cctgtgaaca cgtagtaaac aacatgcgcc acactaagac
    22021 agttggcgtt atcgaagaag acgatgtaac aggattgact cttattgctg aaccagttgg
    22081 tgttgtttgt ggtattactc caacaacaaa cccaacatca acagcaattt tcaaatcatt
    22141 gatttcattg aagacacgta acccaatcgt ctttgccttc catccatcag cacaagaatc
    22201 atctgctcat gcagctcgta tcgtccgcga tgcagctatc gcagctggtg ctcctgaaaa
    22261 ctgtgtgcaa tggattactc aaccatctat ggaagcaaca agtgccctta tgaaccacga
    22321 aggggttgcg acaatccttg caacaggtgg taatgccatg gttaaggcgg cttattcatg
    22381 tggtaaacca gctcttgggg taggtgccgg aaacgttcca gcttatgttg aaaaatcagc
    22441 aaacattcgt caagcagcac acgatatcgt catgtctaaa tcatttgata acggtatggt
    22501 ctgtgcatct gaacaagcag ttatcattga taaagaaatt tacgatgaat ttgtagcaga
    22561 gttcaaatct taccacactt actttgtaaa caaaaaagaa aaagctcttc ttgaagagtt
    22621 ctgcttcggc gtcaaagcaa acagcaaaaa ctgtgctggt gcaaaattga acgctgacat
    22681 cgttggtaaa ccagcaactt ggattgcaga acaagcagga tttacagttc cagaaggaac
    22741 aaacattctt gctgcagaat gtaaagaagt tggcgaaaat gagccattga ctcgtgaaaa
    22801 attgtcacca gttattgcag ttttgaaatc tgaaagccgt gaagatggta ttactaaggc
    22861 tcgtcaaatg gttgaattta acggtcttgg acactcagca gctatccaca cagctgacga
    22921 agaattgact aaagaatttg gtaaagctgt taaagctatt cgtgttatct gtaactcacc
    22981 ttctactttt ggtggtatcg gggacgttta caatgccttc ttgccatcat tgacacttgg
    23041 atgtggttct tacggacgca actcagttgg ggataacgtt agtgccatta acctcttgaa
    23101 tatcaaaaaa gtcggaagac ggagaaataa catgcaatgg atgaaacttc cttcaaaaac
    23161 atactttgaa cgtgattcaa ttcaatacct tcaaaaatgt cgtgacgttg aacgtgtcat
    23221 gatcgttact gaccatgcca tggtagagct tggtttcctt gatcgtatca tcgaacaact
    23281 ggaccttcgt cgcaataagg ttgtttacca aatctttgcg gatgtagaac cggatccaga
    23341 tatcacaact gtaaaccgtg gtactgagat tatgcgtgcc ttcaaaccag ataccatcat
    23401 cgcactcggt ggtgggtctc caatggatgc tgccaaagta atgtggctct tctacgagca
    23461 accagaagtg gacttccgtg accttgtcca aaaattcatg gatatccgta aacgtgcctt
    23521 caagttccca ttgcttggta agaagactaa attcatcgcg attccaacta catctggtac
    23581 aggatctgaa gtaacaccat ttgccgttat ctctgataaa gcaaacaacc gtaaataccc
    23641 aatcgctgac tactcattga caccaactgt ggcaatcgta gatcctgctt tggtattgac
    23701 agttccagga tttgttgctg ctgatactgg tatggacgta ttgactcacg cgacagaagc
    23761 atacgtatca caaatggcta gtgactacac tgatggttta gcacttcaag ccattaaatt
    23821 ggtctttgaa aatctcgaaa gctcagttaa gaatgcagac ttccactcac gtgagaaaat
    23881 gcataacgct tcaacaatcg ctggtatggc ctttgccaat gccttcctag gtatttctca
    23941 ctcaatggcc cataagattg gtgcgcaatt ccacacaatc cacggtcgta caaatgctat
    24001 cttgcttcca tacgttatcc gttacaacgg tacacgtcca gctaagacag caacatggcc
    24061 taagtacaac tactaccgtg cagatgaaaa ataccaagat atcgcacgca tgcttggact
    24121 tccagcttct actccagaag aaggggttga atcttacgca aaagctgtct acgaactcgg
    24181 tgaacgtatt gggatccaaa tgaattttag agaccaagga attgacgaaa aagaatggaa
    24241 agaacattct cgtgaattag ccttcctggc ttatgaagac caatgttcac cagctaaccc
    24301 acgtcttcca atggtagacc atatgcaaga aatcatcgaa gatgcatact atggctacaa
    24361 agaaagacca ggacgccgta aataattgtt tatcagtcta gaagcaagac aaaaactcaa
    24421 tttgagggaa agatccagta atttttctat gataaaaggc atcctatcaa ggtttttgaa
    24481 cacctgatag gatgcctttt tatgatattg aggccttttt gccctttttg aaaaactaga
    24541 atagaaacaa aatatataat agattgaaac tagagtagta cacatctgct tctaaaacat
    24601 tgttagaatt cgatttgact gtcctgatca atttgtcctg ttcttatttc attttaatat
    24661 ataaaaaata t
//
LOCUS       DAVLMQ010000027        23193 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000027 DAVLMQ010000000
VERSION     DAVLMQ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 23193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.027"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            435..1145
                     /gene="deoD"
                     /locus_tag="VXF95_001314"
     CDS             435..1145
                     /gene="deoD"
                     /locus_tag="VXF95_001314"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1081861.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYACELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKKLGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(1168..1692)
                     /locus_tag="VXF95_001315"
     CDS             complement(1168..1692)
                     /locus_tag="VXF95_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HEV1081862.1"
                     /translation="MKIAIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFSPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFEWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(1745..1981)
                     /locus_tag="VXF95_001316"
     CDS             complement(1745..1981)
                     /locus_tag="VXF95_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HEV1081863.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(2049..2969)
                     /locus_tag="VXF95_001317"
     CDS             complement(2049..2969)
                     /locus_tag="VXF95_001317"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HEV1081864.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEKKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVESFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            3159..3526
                     /locus_tag="VXF95_001318"
                     /pseudo
     CDS             3159..3526
                     /locus_tag="VXF95_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3742..4323
                     /locus_tag="VXF95_001319"
     CDS             3742..4323
                     /locus_tag="VXF95_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HEV1081865.1"
                     /translation="MYYAENPDAAHDIHELRVDLLGQKMTFLTDAGVFSKKMVDFGSQ
                     LLLKCLYVNQGETVLDVGCGYGPLGLSLVKVYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            4320..5597
                     /locus_tag="VXF95_001320"
     CDS             4320..5597
                     /locus_tag="VXF95_001320"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HEV1081866.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVRQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            5615..6277
                     /gene="deoC"
                     /locus_tag="VXF95_001321"
     CDS             5615..6277
                     /gene="deoC"
                     /locus_tag="VXF95_001321"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HEV1081867.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYGFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSTVKAFETKEAIQNGADEIDMVINVGALKSGDL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVLACQLAQKAGSDFVKTSTGFSTGG
                     ATIADVRLMRETVGPDMGVKAAGGARSYADALTFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            6264..6653
                     /locus_tag="VXF95_001322"
     CDS             6264..6653
                     /locus_tag="VXF95_001322"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1081868.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDRSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            6743..7795
                     /locus_tag="VXF95_001323"
     CDS             6743..7795
                     /locus_tag="VXF95_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HEV1081869.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            7939..9474
                     /locus_tag="VXF95_001324"
     CDS             7939..9474
                     /locus_tag="VXF95_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1081870.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            9467..10525
                     /locus_tag="VXF95_001325"
     CDS             9467..10525
                     /locus_tag="VXF95_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081871.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            10528..11484
                     /locus_tag="VXF95_001326"
     CDS             10528..11484
                     /locus_tag="VXF95_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1081872.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGVIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            11569..12839
                     /locus_tag="VXF95_001327"
                     /pseudo
     CDS             11569..12839
                     /locus_tag="VXF95_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="programmed frameshift; internal stop; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(12882..13523)
                     /gene="plsY"
                     /locus_tag="VXF95_001328"
     CDS             complement(12882..13523)
                     /gene="plsY"
                     /locus_tag="VXF95_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HEV1081873.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            13659..15602
                     /gene="parE"
                     /locus_tag="VXF95_001329"
     CDS             13659..15602
                     /gene="parE"
                     /locus_tag="VXF95_001329"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HEV1081874.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVVNTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            16022..18493
                     /gene="parC"
                     /locus_tag="VXF95_001330"
     CDS             16022..18493
                     /gene="parC"
                     /locus_tag="VXF95_001330"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HEV1081875.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKKTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            18625..19647
                     /locus_tag="VXF95_001331"
     CDS             18625..19647
                     /locus_tag="VXF95_001331"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HEV1081876.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGIGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            19703..20407
                     /locus_tag="VXF95_001332"
     CDS             19703..20407
                     /locus_tag="VXF95_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1081877.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNSTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGSPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            20472..21161
                     /locus_tag="VXF95_001333"
     CDS             20472..21161
                     /locus_tag="VXF95_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HEV1081878.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            21158..22081
                     /locus_tag="VXF95_001334"
     CDS             21158..22081
                     /locus_tag="VXF95_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HEV1081879.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            22096..22740
                     /gene="pcp"
                     /locus_tag="VXF95_001335"
     CDS             22096..22740
                     /gene="pcp"
                     /locus_tag="VXF95_001335"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HEV1081880.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            22908..23138
                     /locus_tag="VXF95_001336"
     CDS             22908..23138
                     /locus_tag="VXF95_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HEV1081881.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKVVEILIENYNLAK"
BASE COUNT         6983 a         4120 c         5226 g         6864 t
ORIGIN      
        1 ggtttgaaga gattttcgaa gagtataaac agaaaggtag agcgcgtgtt ctaatttgaa
       61 cacgagtaga aaacttttct aaaaacaaaa acgaaaggat gggtaaactg tattcgctga
      121 actgaatacg ggcgactctc ctctaaatca aaattaagaa agaaaggaat tgaaccaccc
      181 taaaagcagt gggaaaaaga tagttggtct agcgagcatc gctcactgcg cccaactcct
      241 attttccctt cgctttttga cgggtttggt atctttctca atataaaata taaaataaag
      301 aaaggtagag cgtgtgtttt gatttgaaca cgagcggaaa actcggaaaa tagataatct
      361 gactgaaaaa tcaggatttc tcgtcaggtt cctaattttc agtcgttttc ttctcgctct
      421 ttgtatcata aattatgtct atccatattg ctgctcagca gggtgaaatt gctgataaaa
      481 ttcttcttcc tggggatcct cttcgtgcta agtttattgc ggagaatttc cttggtgatg
      541 ctgtttgttt taacgaagtg cgtaacatgt ttggttacac tggtacttac aagggtcacc
      601 gtgtatctgt catgggaact gggatgggaa tgccatctat ttcgatttat gcgtgtgagt
      661 taatcgtaga ctacggtgtg aagaaattga ttcgtgtggg aactgcaggt tctttgaatg
      721 aagaggttca tgttcgtgaa ttagttttgg cgcaggcggc tgcaaccaac tcaaacatcg
      781 ttcgtaatga ctggccacag tacgattttc cacaaattgc tagctttgat ttgcttgata
      841 aagcctacca tatcgccaaa aaacttggta tgactactca cgttgggaac gttttgtcat
      901 ctgatgtctt ttactcaaat tactttgaaa agaatatcga gcttggtaaa tggggagtca
      961 aggctgtgga aatggaagca gcagctcttt actatcttgc tgcccaatac catgttgatg
     1021 cgctagctat catgaccatc tctgatagct tggtcaatcc agacgaagac acaactgcag
     1081 aagaacgtca aaataccttc actgatatga tgaaggttgg tttggaaacc ttgattgcag
     1141 aataattata gccaaaaagg aagcccttta tgaattgtag gacttccttt tcttatccag
     1201 aaattgatct agctctctct gatttcgaag aatagtgact ttatgtgaat attcttggca
     1261 aagtttttgg taattttctt tttgagtttt gctacgccca tcccaaagaa tccatctgat
     1321 aaactcccac tcaaagcgtt cagggcaatc tgccgccata ctttctctga cttttccacg
     1381 gtatttaaga taacgcttaa aggctctaaa gagacaggtc aatggcgaaa aattgagaaa
     1441 gatgatttgg tcagcttctt gcattcgttc ttggtagtag caccaagaat aattaccatc
     1501 gatgacccaa gctttatgct tggtgagaaa gttttttatc tcggttaaca tccattcgca
     1561 gtcactgtct tgccaaccag gttgaaattg gagtgtgtcc atgtgcagtt ttggaatgga
     1621 gtagtagtta gataactttt ctgctagagt tgacttacca gaaccagaat atccgataat
     1681 tgcgattttc attttctacc ttttcctatt tggagacaaa aaaacagcct ctatggactg
     1741 tttcttattt agcaagttta gctgaaagac gagctttatc gcggcttgct ttgtttttgt
     1801 gaatcaaacc tttagtttct gctttatcga tagctgagct agcagcacgg aaaagttctt
     1861 cagatgggtt tgcttcgaaa gcttttatag cagtacgcat agctgatttt tgagctgagt
     1921 tcttttcgtt ttgtttaacg ttcaattcag cgcgtttgat agctgattta atgtttgcca
     1981 atgttcttac ctccatattt actaactata ccattatata tgaaaactta cgttttgaca
     2041 agggaaaatt acttttttaa gtaaatttca tcgatttcat ggttcttgct tttatgaaga
     2101 atcacttctg cacgatttct ggttggttca atataatttt gcagatttgt gagattgata
     2161 ctggtccaga cctgatgggc aaaggactcc acttccccaa tcggcatctg agtaaaacga
     2221 taatagtagc tatcagggtc gttttgggct aggctcagca ttttcaagaa acggtccaga
     2281 taccaacttt caatatcatc cactccagca tctacataga tggaaaagtc aaagaagtca
     2341 gtgatataga gacgatcgtt ttgtggattt tgaaagacat taattccctc aacaattaca
     2401 aaatcagcag ctttgacact ttgtttcttt tcgggtacga tgtcgtaaac ttcatgagaa
     2461 tagacaggaa tatctacatc ttgtccattt ttgatgcggt ccaagaagtt gagaagagct
     2521 tccatatcat agctttcagg aaatccttta cgatttaaaa tcccctgctc aatcaaggtt
     2581 tgattgggat agagaaaacc atcagttgta accaactcaa ccgtagcatc tgtaaacgta
     2641 cgggacagta ggatttgaag taggcgactg gttgtggatt ttccaacggc aacactccca
     2701 gaaaccccaa taataaaagg ttgagattta ctttcacgtt ggaggaaaat tccttttgaa
     2761 aaggctaaat cttccttagt tcgcttgtaa atctgaatca gatgagccaa ggggagatag
     2821 atatctgtaa cgtcttggag actgatttgg tcattaaaac tcttgataga ttccaattct
     2881 tcttctgtca aaggaggtgt tgtctttcga tgtaaagatt gccaagtctg gcggctgatt
     2941 ttttcaaaat gtaaaaattc gttggtcatt tgttttcccc taggtatttt atctatcata
     3001 ccataaaaag ctaaaaaaat aaagcggttt cttgaatgtt gtaagtcaat gatatataat
     3061 ataagcgatc aatttattga tgaaatagga gatagattct actgatttat aagcttataa
     3121 agggggcttt ttagttcaca acttatagga gatgtactat gaaaatctta aaacgttaca
     3181 tattggaact ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag
     3241 ataatggtag atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta
     3301 ttgtaacagc tgtctttatc tgttcgttct taattgctgt cttactaaaa aacgatgggc
     3361 gaaatggatt gcgacagagg gttatttctt ccgcatgtca ctagaagatt tgatacgact
     3421 ttggacaagt ttggaaatcc tgacacaaac gtatcagttg ggcttttatc taaacatttt
     3481 gttaggaatt ttgttgataa taaagtattt taaggttaag caatagaaat aataatctgc
     3541 ctgattatag atgataaact ttttgttttt atctggactg tgatatttat agttctaaat
     3601 ggtttattat ttataagtgt tgaaagagat tgaagaaaat ggcttcgtga cttgctttct
     3661 tcggtctttt tcgttttatt atcaatttgt aaacgattta caatttgagt caaattatgg
     3721 taaaatagtg tcatgagtaa aatgtattat gcagaaaatc ctgacgctgc tcacgacatt
     3781 catgagttga gagtggactt gttgggacaa aaaatgactt ttttgacaga tgcgggtgtt
     3841 tttagcaaga aaatggttga ctttggaagt caactcttgc tcaagtgtct gtatgtcaac
     3901 caaggagaga cagtcctaga tgtaggctgt ggttatggtc cattaggttt gtccttggtc
     3961 aaggtttacg gagttcaggc gaccatggtt gatattaaca ctcgtgcctt ggatttagct
     4021 cggagaaatg ctgaaaaaaa taatgcaaaa gcgacgattt tccagtccaa catctatgaa
     4081 caagttgaag gacattttga tcatgtcatt tccaatcctc ctatccgtgc gggcaagcaa
     4141 gtcgttcatg aaatcattga gaaaagtaaa gatttcttgg aaactggtgg ggatttgaca
     4201 atcgtcatcc agaaaaaaca aggggctcca agtgctaagt ccaagatgga ggatgtgttt
     4261 ggtaattgtg aaatccttaa aaaagacaaa ggatactata tccttagaag tgtgaaagaa
     4321 tgagagcagt tgatttaata caaaaaaaac gagacggtca agaactgact tcaagtgaaa
     4381 ttgaatggct ggtagaaggc tatgtgtcag gaactgttcc tgattatcag atgtctgcct
     4441 ttgctatggc tgtttatttt aaaggaatga cgactcgtga aatttctgat ttaacgatga
     4501 atatggttaa gactgggcaa gagtttgacc tgtcagccat tgatggtgtg aaagttgaca
     4561 agcattctac tggtggtgtc ggcgataagg taaccttgat tttagctcct cttgttgcta
     4621 gcttcggtgt gcctgtagca aaaatgagtg gtcgtggtct tggccataca ggcggaacaa
     4681 ttgataaatt ggagtccatt aagggctatc aagtagaacg tagtcaagag gattttattc
     4741 gtcaggttca ggatattgga gtatctgtca ttgggcaatc agaccagctg gtcaaagcag
     4801 ataagcttct ctatgccctt cgtgatgtga ccgcaactgt cgacacgatt cctttgattg
     4861 cgagttcggt gatgagcaag aaaattgcgg caggggcaga tgctattttg ctagacgtga
     4921 ctgtcggtga gggtgccttc atgaagacgg ttgatgaggc gcgtgagttg gctcaaacta
     4981 tggtagatct tggtaaggtt gttggacgga agacagtagc agtgattacg gatatgagcc
     5041 agcctttggg acgagcgatt ggaaatcgtc tggaaatcct tgaagcattg gagattttgc
     5101 aaggtcaagg acgtcaggat attacccact ttatttgtga attggctcaa attatgcttg
     5161 gtttggcaaa tgttaacaaa actgttgaag aagttcgcca acatcttgag aatggtcaag
     5221 cactggctaa gtttgaggaa atggtgcaag cccaaggtgg agacttggaa gacctctatc
     5281 gtcctgtaaa tgtagctcat gtggtggaaa tccctgctca ggaaacgggt gtcatttcag
     5341 ctcttccagc tatggacttt ggtctttatg ccatgaggct gggtgctggt cgtgcagtta
     5401 agtctgatgc cttggactat gaaacaggaa ttgtttttga aaagaagatt ggagactccg
     5461 ttcaaaaggg tgaaattgtt gcaaaagtat acacaaatga aaaaattcca cctcaactag
     5521 ttacagattt ccaaaaatgt gttaaaataa gtgatgaagt gaaaaaaatc cgtgaaattg
     5581 tagaaatcat ctcctaaatg gagggaaaac cgaaatgaaa ttaaataaat atatagatca
     5641 tacgctttta aaacaagatg caaagaaaaa acaaattgat agtttgttgt ctgaggctag
     5701 agagtatggc tttgccagtg tttgcgttaa tccgacctgg gttgaacatg ctaaaaaagg
     5761 acttgaaggc acagatgtta aggtttgcac agtagtaggt ttccccttgg gagcaacaac
     5821 ttcaactgtg aaagcttttg aaacaaaaga agctatccaa aatggggctg atgagattga
     5881 catggtaatc aatgttgggg ctctcaagtc aggtgatttg gccttggttg agtcggatat
     5941 tcgtgcagta gtggaagcaa gtggggacaa gttagtgaaa gtcattattg aagcttgcct
     6001 tctgacagac caagaaaaag ttttggcttg ccaattagcc caaaaagcag gatctgactt
     6061 tgtcaaaaca tctactggct tttcaactgg tggtgctacg atagcagatg ttagattaat
     6121 gcgtgaaaca gttggacctg atatgggtgt caaggccgcc ggtggagctc gttcttatgc
     6181 agatgctctt acctttgtcg aagcaggtgc gacccgtatc ggaacgtcag ctggggtagc
     6241 tattttaaaa ggagaattgg cagatggcga ctactgagtt gattgaactg gcaattgaaa
     6301 ccagcaaaca tgcctatgtc ccctattctc actttcctat cggagcagtt ttagtagcca
     6361 aagaccgaag tgtttacacg ggagtgaata tcgaaaatgc tagctatcct ttgaccaatt
     6421 gcggtgagag aacagctatt tttaaggcta tatctgaagg ccaaagagaa ttttcagaat
     6481 tgattgtcta tggtcaaact gaaaaaccga tttcaccatg tggtgcttgt cgccaagtaa
     6541 tggtcgaatt ttttgaacaa gatttaaaag tgaccttagt cgcaaaagat aaatcgacgg
     6601 tcgagatgac ggtcggggaa ttacttccat actcttttac agacttaaac tagtctgagt
     6661 cgctctctga gtggcacggt ccttgtggcc aaccaatcca tacttgcaac atcgttgcac
     6721 atcttattta ggaggttcag taatgaacaa gaaacaatgg ctaggccttg gtctagttgc
     6781 agtggcagca gttggacttg ctgcatgtgg taaccgctct tctcgtaacg cagcttcatc
     6841 ttctgatgtg aagacaaaag cagcaatcgt cactgatact ggtggtgttg atgacaaatc
     6901 attcaaccaa tcagcttggg aaggtttgca ggcttggggt aaagaacaca atctttcaaa
     6961 agataacggt ttcacttact tccaatcaac aagtgaagct gactacgcta acaacttgca
     7021 acaagcggct ggaagttaca acctaatctt tggtgttggt tttgcccttc acaatgcagt
     7081 tgaagaagca gctaaagaac acactgactt gaactatgtc ttgattgatg atgtgattaa
     7141 agaccaaaag aatgttgcga gcgtaacttt cgctgataat gagtcaggtt accttgcagg
     7201 tgtggctgca gcaaaaacaa ctaagacaaa acaagttggt tttgtaggtg gtatcgaatc
     7261 tgaagttatc tctcgttttg aagcaggatt caaggctggt gttgcgtcag tagacccatc
     7321 tatcaaagtc caagttgact acgctggttc atttggtgat gcggctaaag gtaaaacaat
     7381 tgcagccgca caatacgcag ccggtgcaga tattgtttac caagtagctg gtggtacagg
     7441 tgcaggtgtc tttgcagagg caaaatctct caacgaaagc cgtcctgaaa atgaaaaagt
     7501 ttgggttatc ggtgttgatc gtgaccaaga agcagaaggt aaatacactt ctaaagatgg
     7561 caaagaatca aactttgttc ttgtatctac tttgaaacaa gttggtacaa ctgtaaaaga
     7621 tatttctaac aaggcagaaa aaggagaatt ccctggcggt caagtgatcg tttactcatt
     7681 gaaggataaa ggggttgact tggcagtaac aaacctttca gaagaaggta aaaaagctgt
     7741 cgaagatgca aaagctaaaa tccttgatgg aagcgtaaaa gttcctgaaa aataatggat
     7801 ggaagtcatt tcttaggaag cggccaaggg ccgctttttt aagagttgag acaaagtcat
     7861 tttgtctcag taaagcttgc tactagacaa actagcaagt tttattgaaa taaaataaga
     7921 ctctgaaagg aagagcacat ggcacacgaa aatgtcattg agatgcgtga tattaccaag
     7981 gtgtttggtg gatttgttgc caacgacaaa atcaacttgc acctacgaaa aggtgaaatt
     8041 catgcacttt taggagaaaa tggggctggt aagtccacgc taatgaacat gttagcaggc
     8101 cttcttgaac caactagtgg tgaaatcgcg gtcaacggtc aagttgtcaa tctcgactcc
     8161 ccatctaaag cagctagctt gggaatcggg atggttcacc agcactttat gttggttgaa
     8221 gccttcacag tggctgaaaa catcatttta ggtagtgaat tgactaaaaa tggtgtgcta
     8281 gatatcgctg gagctagcaa agaaatcaag gctctttctg aacgttatgg cttagctgtt
     8341 gacccttctg ccaaggtagc agatatctca gttggagccc aacaacgtgt agaaatttta
     8401 aaaacacttt atcggggggc tgatatcctt atctttgacg aaccaacggc tgttttgact
     8461 ccatcagaaa ttgatgagtt gatggctatt atgaaaaatc ttgtcaaaga aggaaaatca
     8521 attatcttga ttacccacaa attggatgaa attcgcgcag tttctgaccg tgttacagtt
     8581 atccgtcgtg ggaaatcaat tgaaaccgtt gaaattgcag gggctaccaa tgctgatttg
     8641 gcggaaatga tggtaggacg ttctgtttcc tttaaaacag agaagcaagc ctctaaacca
     8701 aaagaagtgg ttttgtctat caaagatttg gtggtcaatg aaaaccgtgg tgttccagct
     8761 gttaaaaatc tgtccttgga tgttcgtgct ggagagattg ttggtattgc ggggattgat
     8821 ggaaatggtc agtctgaact gattcaagcc attacaggtc ttcgtaaggt tgaatctggt
     8881 agcattgagc taaaaggaga ttcaattgta ggcttgcacc cacgtcagat tacagaacta
     8941 agtgttgggc acgttccaga agaccgtcac cgtgatggct tgattttgga aatgatgata
     9001 tctgaaaata ttgcccttca aacctactat aaagaaccac atagtaaaaa tggaattttg
     9061 aattattcaa atattacttc ttatgctaaa aagctgatgg aagagtttga tgttcgcgct
     9121 gccagtgaat tagttcctgc agctgcactc tcaggaggaa atcaacaaaa agcaattatt
     9181 gctcgtgaaa ttgatcgaga tcctgatctc cttatcgtta gccagccaac tcgtgggttg
     9241 gatgtcggtg ccattgagta tatccacaaa cgcttgattg aagagcgtga taatggcaag
     9301 gctgtccttg ttgtcagctt tgaattggat gagattttaa acgtctcaga ccgtattgcc
     9361 gttatccacg atggtaagat tcaaggtatt gtatcaccag aaacaaccaa taaacaagaa
     9421 cttggtgtct tgatggctgg tggaaacttg ggaaaggaga agagtgatgt ctaaaaaatt
     9481 acaacaaatt tcggttccct tgatttctgt atttctagga attttactcg gagccattgt
     9541 catgtggatc ttcggttatg atgctatttg gggctacgaa gaattgttct atacagcctt
     9601 tggcagtctg cgtgggattg gagaaatctt ccgtgctatg ggtcctctgg tcttgattgg
     9661 tcttggtttt gcggttgcca gtcgagctgg tttctttaac gtcggacttc ctggtcaggc
     9721 tttggcaggt tggattctca gtggttggtt tgcgctgtcg catccagata tgccccgtcc
     9781 cttgatgatt ctagcaacca tcgtgattgc cttgattgct ggtgggattg tcggagcgat
     9841 tccaggtatt cttagggcct atctagggac gtcagaggtt attgtaacca tcatgatgaa
     9901 ctacattgtc ttgtatgtag ggaatgcctt tatccatgct ttccctaaag acttcatgca
     9961 aagtacagat tcgaccattc gtgttggggc taatgcaacc tatcagacac cttggttggc
    10021 tgagttgact ggtaactcac ggatgaatat tggtattttc tttgccatca ttgccgttgc
    10081 agttatttgg ttcatgctca agaaaacaac tcttggtttt gaaatccgtg cagttggtct
    10141 taatccacat gcttcagaat atgctggtat ttctgccaag cggactatta tcctatctat
    10201 gattatttca ggtgccttgg caggtcttgg tggagctgtt gaaggtttgg gaaccttcca
    10261 gaacgtctat gttcaaggtt cgtcattagc tatcggattt aacggaatgg cggttagttt
    10321 gcttgcggcc aactcaccaa ttggtatact ttttgcagcc ttcctatttg gcgttctcca
    10381 agttggggct cctggtatga atgcggcgca ggtaccatct gagcttgtca gcattgtaac
    10441 agcgtctatt atcttctttg tcagtgttca ttaccttatc gaacgctttg tcaaaccgaa
    10501 aaaacaagtt aaaggaggta agtaaagatg tctattataa ccttgctccc cctcttggtg
    10561 tcttctatgc tgatttactc agcacctctc atctttacaa gtatcggtgg tgttttctct
    10621 gaacgtggtg gtgtggtaaa cgttggcctt gaaggaatta tggttatggg tgccttttct
    10681 ggagttgtct ttaaccttga atttgcagaa caatttggag cagcaactcc atggctatcc
    10741 ttgcttgtag caggattggt tggtagtgtt ttctctatca tccacgcagc agcgacggtt
    10801 catttccgtg cagaccatgt tgtcagcggt acggtattga acttgatggc gcctgccttg
    10861 gctgttttct tagttaaagt tctctataac aaaggacaaa ccgacaacct aagtcaaact
    10921 tttggacgct ttgatttccc agtcttggca aatatcccag tgattggtga tatcttcttc
    10981 aagtcaacta gtctacttgg ttatctggcg attgccttct cattccttgc ttggtttatt
    11041 ctctttaaga ctcaatttgg tcttcgtctc cgctctgtcg gtgaacatcc tcaagcagcg
    11101 gataccctgg gaatcaacgt ctacaagatg agatatttag gggttattat ttcaggtttt
    11161 ctaggtggaa ttggcggagc gatttatgcg caatcaatct cagttaactt ctcagtgaca
    11221 actattgttg gacctggatt tatcgccctt gctgcgatga tctttgggaa atggaatcca
    11281 atcggtgcta tgctttctag tctcttcttt ggactttcac aaagtttggc tgttatcggt
    11341 tctcaattgc cgttcctaca aggagtgcca gcggtttatc ttcaaattgc accttatgtt
    11401 ttgacaattc ttgtcttagc agccttcttt ggaaaagcag tcgcaccaaa agcagatggt
    11461 atcaactaca tcaaatcaaa ataagcatac aaaaaaacgt cagtccaatg actgaactgc
    11521 accccaaaag ttagacagaa aaaatctaac ttttggggtg tttttattat gaaattgagt
    11581 tgtgatgata aagttcagat ctatgaactt agaaaacaag gatatagctt agagaagctt
    11641 tcaaataaat ttgggataaa caattctaat cttaggtaca tgattaaatt gattgatcgt
    11701 tacggaatag agttcgtcaa aaaagggaaa aatcgttact attctcctga tttaaaacaa
    11761 gaaatgattc ataaagtctg acatgaaggc tggactaaag atagagtttc tcttgaatac
    11821 tgtctcccaa gtcgtacgat acttcttaac tggctagcac aatacaggaa aaacgggtat
    11881 actattgttg agaaaacaag agggagagta cctgagagcg gagaatgcca tcctaaaaaa
    11941 gttaagagaa ctccgattga aggaggaaaa agagaaataa gaaagacaga aattgttcaa
    12001 gaattaatga ctgagttttc gttagatctt cttctaaaat ccattaaact agctcgttcg
    12061 acctactact atcacttgaa acagctagac aaaacagata aggaccaaga gcttaaagct
    12121 gaaattcaat ccatctttat cgaacacaag ggaaattatg cttatcgtcg gatttattta
    12181 gaactaagaa atcgtggtta tctggtaaat cataaaagag ttcaacactt gatgaagtac
    12241 tcagtttaca agctaaaacg cgacagaaac gaaaatattc ttctcataaa ggagacgttg
    12301 gcaagaaggc agagaatctc attcaaggcc aatttgaagg ctctaaaaca atggaacagt
    12361 gctacacaga tgtgactgaa tttgccattc cagtaagtac tcaaaagctt tacttatcac
    12421 cagttttaga tggctttaac agcgaaatta tcgcctataa tctttcttgt tcgcctaatt
    12481 tagaacaagt acaaacaatg ttggaacagg cattcaaaga gaagcactat gagaatacga
    12541 ttctccatag tgaccaaggc tgtcaatacc aacacgattc ttatcatcgg ttcctagaga
    12601 gtaagggaat tcaagcatcc atgtcacgca agggaaacag ccaagacaac ggtatgatgg
    12661 aatctttctt tggcatttta aaatccgaaa tgttttatgg ctatgagaaa acatttaaat
    12721 cacttaatca attggaacaa gccattatag actatattga ttattacaac aacaagagaa
    12781 ttaaggtaaa actaaaagga cttagccctg tgcaatacag aactaaatcc ttcggataaa
    12841 ttaattgtct aactgtttgg gggcagtaca gaactggcgt tttatttttt aggatcttga
    12901 tgagttaggt tcaatcccca agggaccaaa ttttcagttt tatttttgat acgagctata
    12961 ttgtccttat gacgaatgat aatcaaacta gcaagtgcta agataatagc gatgaagaga
    13021 gagtcatagt tactcaggat aaaaccaaaa agtggaaaga gcagaacccc gataacagcc
    13081 gcgatcgatg ctgtgacact agacagtgaa atcatactgc caagatagag agctccaaag
    13141 aagataatcg caaggtagag acagaagata ggcgcaaatc cgaaaatcac tccagcactg
    13201 gttgcgacag ccttaccacc tttaaatcct gcaaagatag ggaaggtatg gccgataaca
    13261 gccaaaagtc caaagatgag aggagaaacg ccttgtagat gaaaaataat cggaagcagc
    13321 gttgctaggg ttcctttgaa aaagtcaatc acaaaggttg ccataccagc tttcttacct
    13381 aaaatgcgga aggtattggt cgttccagtg ttaccagaac catgctcgcg tagattgatt
    13441 tgaaagaata cttgtccaat ccagagacca gatggaatcg aacccagcag ataggctagg
    13501 attaataaaa ctattgtaat catactccta ttatatcatg aattgggaaa gaaaagcaga
    13561 gaatctctgc tgaaattgtc acatcggaga aagaaaaatt ttgcaaaatc cttggaaaac
    13621 ctgtagaata gtaaagatga acgaatagga ggttccttgt gtcaaaaaag gaaatcaata
    13681 ttaacaatta taatgatgat gctattcagg tgctagaagg gttggatgcg gtccgaaaac
    13741 gtccggggat gtatattgga tcgaccgatg gcgctggtct tcatcaccta gtttgggaaa
    13801 tcgttgataa tgcagtcgat gaagccttgt ctgggtttgg tgatcgtatc gatgtaacta
    13861 tcaataaaga cggtagtcta acggttcaag accatggacg tgggatgccg acaggtatgc
    13921 acgctatggg aattccaact gttgaggtta tctttaccat tcttcatgcc ggagggaaat
    13981 tcggtcaagg tggctataag acatcaggtg gacttcacgg agtgggttct tccgttgtta
    14041 acgccctttc tagctggtta gaagttgaaa ttacccgtga tggcgcagtt tacaagcaac
    14101 gtttcgaaaa tggtggaaaa cctgtcacga ctttgaagaa aatcggtaca gcacccaagt
    14161 ctaaaacagg caccaaagtt acttttatgc ctgacgcgac tatcttttct acgacagatt
    14221 tcaagtacaa taccatttca gagcgcctta atgaatcagc ctttctcttg aaaaatgtga
    14281 ccttgtcttt aacggacaag cgaacagatg aagcgattga gttccactat gagaatggag
    14341 tacaagattt tgtttcttat ctcaacgaag ataaggaaat cttgacgcca gttctttact
    14401 ttgaagggga agacaatggt tttcaagtgg aagtagccct ccagtacaat gacggattct
    14461 cagataacat tctatccttt gtcaataacg ttcgcaccaa ggacggtgga acgcacgaga
    14521 caggactcaa gtctgccatt accaaggtca tgaatgacta tgcacgtaaa acaggtcttc
    14581 tcaaggaaaa agataaaaac cttgaaggtt cagactatcg tgagggacta gcggccgttc
    14641 tttctatctt agttcctgaa gaacacttgc agtttgaagg acagaccaag gataaactag
    14701 gaagccccct agctcgccca gttgtggatg gaatagtggc tgataagttg acctttttcc
    14761 ttatggaaaa tggggaatta gcttctaacc tcatccgcaa ggctatcaag gcccgtgatg
    14821 ctcgtgaagc agcacgtaag gcgcgtgatg agagccgaaa tgggaagaaa aacaagaaag
    14881 ataagggctt gttgtctggg aaattgaccc cagcccaatc taagaatcct gctaagaatg
    14941 aactctatct agttgagggg gactctgccg gtggttctgc caaacaaggt cgtgaccgca
    15001 agttccaggc tattctacct cttcgtggta aggttgtcaa tacagccaag gccaagatgg
    15061 cggatatcct caaaaatgaa gagatcaata ccatgattta taccattggt gcgggtgttg
    15121 gagcagactt ctctattgaa gatgccaact atgataagat cattatcatg accgatgcgg
    15181 ataccgacgg tgcccatatc cagaccttgc tcttgacatt tttctaccgt tacatgcgtc
    15241 cgctagtcga ggcaggtcat gtctatattg ccctcccacc tctttacaag atgtccaaag
    15301 gtaaaggcaa gaaagaagaa gtggcctacg cttggacgga cggagaacta gaagaactcc
    15361 gtaaacagtt cggtaaaggc gctaccctcc aacgatacaa aggacttggt gagatgaatg
    15421 cggaccagct ctgggaaaca accatgaacc cagaaacacg taccctcatc cgtgtcacaa
    15481 ttgaagattt agcgcgcgcc gaacgccgcg tcaatgttct catgggagat aaggtagaac
    15541 cacgccgtaa atggattgaa gataatgtca agtttacgct agaagaagcg acagtgtttt
    15601 aatgaaagaa aataatatgt tagtaaactg gaaattagag tcggatgtga atgactatgt
    15661 aaaaaagcag tttgaaaatc ttggtttgaa aaaattgcag gattattaat gaagaatctt
    15721 ctatgagtgc ttatctcaaa gaggcgttta agggagcggc taagacacaa actaagacta
    15781 attttggaaa accagatttt catattgaaa aatacaaaca ggatagtttg gttacttatc
    15841 gtaactgaac acgggacgaa ttcccgtaaa atatctttta ctgcataaaa acctactcta
    15901 cattctttga aaggagttga acacgcccta gatactgtgt gaaaaagata aattctcttg
    15961 tgagtttgct tacttcaaga attttctatt ttcacttggt attttatggg ctttgtatct
    16021 tatgtctaac attcaaaaca tgtccctgga ggacatcatg ggagagcgct ttggtcgcta
    16081 ctccaagtac attattcaag accgggcttt gccagatatt cgtgatgggt tgaagccggt
    16141 tcagcgccgt attctttatt ctatgaataa ggatagcaat acttttgaca agagctaccg
    16201 taagtcggcc aagtcagtcg ggaacatcat ggggaatttc cacccacacg gggattcttc
    16261 tatctatgat gccatggttc gtatgtcaca gaactggaaa aatcgtgaga ttctagttga
    16321 aatgcacggt aataacggtt ctatggacgg agatcctcct gcggctatgc gttatactga
    16381 ggcacgtttg tctgaaattg caggctacct tcttcaggat atcgagaaaa agacagttcc
    16441 ttttgcatgg aactttgacg atacggagaa agaaccaacg gtcttgccag cagcctttcc
    16501 aaacctcttg gtcaatggtt cgactgggat ttcggctggt tatgccacag acattcctcc
    16561 ccataattta gctgaggtca tagatgctgc agtttacatg attgaccacc caactgcaaa
    16621 gattgataaa ctcatggaat tcttgcctgg accagacttc cctacagggg ctattattca
    16681 gggtcgtgat gaaatcaaga aagcttatga gactgggaaa gggcgcgtgg ttgttcgttc
    16741 caagactgaa attgaaaagc taaaaggtgg taaggaacaa atcgttatta ctgagattcc
    16801 ttatgaaatc aataaggcca atctagtcaa gaaaatcgat gatgttcgtg ttaataacaa
    16861 ggtagctggg attgctgagg ttcgtgatga gtctgaccgt gatggtcttc gtatcgctat
    16921 cgaacttaag aaagacgcta atactgagct tgttctcaac tacttattta agtacaccga
    16981 cctacaaatc aactacaact ttaatatggt ggcgattgac aatttcacac ctcgtcaggt
    17041 tgggattgtt ccaatcctgt ctagctacat cgctcaccgt cgagaagtga ttttggcgcg
    17101 ttcacgcttt gacaaagaaa aggctgagaa acgtctccat atcgtcgaag gtttgattcg
    17161 tgtgatttcg attttggatg aagtcattgc tcttatccgt gcttctgaga ataaggcgga
    17221 cgccaaggaa aacctcaaag ttagctatga ttttacggaa gaacaggctg aggctatcgt
    17281 aactttgcaa ctgtaccgtt tgaccaatac cgatgtggtt gtcttgcagg aagaagaagc
    17341 agagcttcgt gagaagattg ctatgctggc ggctattatc ggtgatgaaa ggactatgta
    17401 caatctcatg aagaaagaac ttcgtgaggt caagaagaaa tttgcaactc ctcgtttgag
    17461 ttctttagaa gacactgcga aagcaattga gattgataca gctagtctta tcgctgagga
    17521 agatacctac gtcagcgtga ccaaggcagg ttacatcaag cgtaccagtc cacgttcctt
    17581 tgcggcttcc accttggaag aaattggcaa gcgtgatgat gaccgtttga tttttgttca
    17641 atctgccaag acaacccagc acctcttgat gttcacaagt cttggaaatg tcatctacag
    17701 accaatccat gagttggcag atattcgttg gaaggacatc ggagagcatc tgagccaaac
    17761 catcacaaac tttgaaacga atgaagaaat cctttatgtg gaagtactgg atcagtttga
    17821 cgatgcgaca acctactttg cagtgactcg ccttggtcaa atcaaacggg tagagcgaaa
    17881 agaattcact ccatggcgga cctatagatc taagtctgtc aagtatgcta agctcaaaga
    17941 cgatacagat cagattgtag cagtggctcc gattaaacta gatgatgttg tcttggttag
    18001 tcaaaatggt tatgccctgc gtttcaatat cgaagaggtt ccggttgtcg gtgctaaggc
    18061 agcaggtgtc aaggctatga atttgaaaga agatgatgtc ctccaatctg gctttatctg
    18121 taatacttcg tccttctacc tcttgaccca gcgtggaagc ttgaaacgtg tttccattga
    18181 ggaaattcta gcaaccagcc gtgccaaacg aggattacaa gtcttgcgtg agttgaaaaa
    18241 caaaccgcat cgtgtcttct tggcaggagc agttgcagag caaggatttg ttggcgattt
    18301 cttcagtacg gaagtggatg tgaacgacca aactctactt gtccaatcca ataaaggaac
    18361 aatctatgaa agccgattgc aagacttgaa cttgtcagaa cgcactagca atggaagctt
    18421 catttctgac acgatttcag atgaagaagt ttttgacgct tatcttcagg aagtagttac
    18481 tgaagataaa taagtgaaat gaagaatcag ttctaagagc tggtttttat tggagaaatt
    18541 ttctgaaaat tacaaaatat acttgctatt ttagaaaaat agtgtagaat ataagaaata
    18601 ggtttttaga ataaggagtg gaatatgaca gtaacgattg attgggaaaa cctcggtttt
    18661 tcctatatga aattacctta tcgctatctt gctcatttca aaaatggaca atgggatcaa
    18721 ggagagctta cagaggatgc aactttgcat atttcagagt cttctccaag tcttcactat
    18781 ggacaacaag catttgaagg tttgaaagct tatcgtacta aggatggcag tgttcaactg
    18841 ttccgtcctg atgaaaatgc taaacgcctg caacgtacat gtgaccgtct cttgatgcca
    18901 caagttccga cagacatgtt tgtagaagct tgtaaagcag ttgtccgtgc gaatgaagaa
    18961 tacgtaccac catacggaat aggtggaact ttatatcttc gccctctttt gattggtgtc
    19021 ggagatatta tcggggtaaa accggcagaa gagtacattt tcaccatctt tgctatgcca
    19081 gttggaaatt actttaaagg tggtttggtc ccaaccaact tcttgattca ggatgagtac
    19141 gaccgtgcag caccaaatgg tacaggtgcg gctaaggttg gtggaaacta tgctgcaagt
    19201 ctcttaccag gaaaaatggc caagtcacgc catttctcag atgttatcta tctggaccca
    19261 tcaactcata caaagattga agaagtcgga tcagctaatt tctttggaat tacagctgat
    19321 aatgaatttg taacaccatt gagtccatct atcttgccat ctattaccaa gtattccttg
    19381 ctttatttgg cagaacatcg cttgggatta actcctattg agggtgatgt tccaattgat
    19441 aatcttgacc gttttgtaga ggcaggtgcc tgtggtacag cagcggttat ttctccaatt
    19501 ggaggtattc aacatggtga tgatttccat gtattctata gtgaaacaga agtaggtcct
    19561 gtgacgcgta aattatataa tgaattgacg ggtattcagt ttggcgatat tgaagcgcca
    19621 gaaggttgga ttgtaaaagt agattaaaat aaaccaaagg agatttttta tgaaatagaa
    19681 aaagtggctc ttaacagcag gagtggtcct gagcacgtca gctattttag tggcttgtgg
    19741 aaaaactgat aaagaagcag atgcaccgac aacattttct tatgtctatg cagtagatcc
    19801 agcatcattg ggctacagta tagcgactcg aacatcgagg acagacgtta ttggaaatgt
    19861 tattgatggt ttgatggaaa atgataaata cggcaatgtt gctccttctc aaaaagacta
    19921 tgatttgaac agtacaggat gggctccaag ctatcaagat ccagcgtctt acttgaatat
    19981 tatggatcca aaatctggtt ctgccatgaa acaccttggc attacgaaag gaaaagataa
    20041 ggatgttgta gctaaacctg gtttggataa atataagaaa ttgttagaag atgctgtttc
    20101 tgagaccact gacctagaga agagatatga aaaatatgcc aaagctcaag cttggtcgac
    20161 agatagttca ttattgatgc caacagcttc atctggtggt tctccagttg taagtaacgt
    20221 agtaccattc tcaaaaccat actcacaagt tggtattaag ggggaaccat atatctttaa
    20281 aggaatgaaa ttgcaaaaag atattgttac aacaaaagaa tataacgagg tttttaaaaa
    20341 atggcaaaaa gaaaaattgg aatccaatag caaataccaa aaagaactag aaaaatacat
    20401 taaataagga atggtattga tcttgataaa atttttaaaa tactgtcatt ttgaatataa
    20461 aggagtttga tatggagtgg attagattaa taggaatagc aatcattgtt gtgggtttta
    20521 ttttaaaatt tgatacaatt gcaacagtag tcttagctgg tttggttaca gctttagttt
    20581 caggtgtttc tctcgttgaa tttttggaga ttttgggaaa agaatttagc aatcagcgag
    20641 tgctcacgat ttttatggtt accttgcctc ttgtggggct gtcagaaacc tttggactca
    20701 agcaacgatc aatcgatttg attcgaaaga ttaaaggtct gacagttgga aacttctata
    20761 cagtttattt ctttattcga gagttagctg gtttcttttc aattcgtcta ggaggacacc
    20821 ctcagtttgt cagacctttg gttcaaccta tgggagaagc agctgcagag tctcaattag
    20881 gtagaaagtt aacagaggtt gaagatgaga caataaaagc gcgtgcggct gcgaatgaaa
    20941 attttggaaa tttctttgct caaaatacgt ttgtaggtgc tgggggagtc ctcttgatag
    21001 ggggaacatt agatcagtta ggctatgaaa gcaattatgc agggattgct tctacatcta
    21061 ttattgttgc tgttataaca cttattgtag tggggattta caattattta tttgataaaa
    21121 aattgatatc aaaaaagact aggggaggag aacaaaaatg acagagttgg caaagcaact
    21181 attagagttg acctatattg tgattggttg tcaatttctc catacagcct attgtagtta
    21241 taaagataaa acaaacccag ttcgacttgg gacatctgca ttttggactc tattgtctat
    21301 tacgtttata ggtggttcct atatgccaaa tatgagtatt ggtattattg taatcctatt
    21361 atcgctgtta acattgttta agcaagtccg tatcggaacc ttgccatcct tagatgaaat
    21421 gaaagccaat attgaatcta acaggttgaa aaataaaatt tttattccag ttatgctgat
    21481 ggcaatactt gcgttggtct tagcgcaaat gattccagaa tttagcaaga tttcgattag
    21541 ccttgccgcc ttgtttgcta caatttctgt tcttgtgatt accaatagtc accctaagag
    21601 tctgttatca gaaaataatc gaatgactca gcaagtttca acaagtggga ttgttcctca
    21661 attattaggg gctttggggg ctatttttac tgtagcaggt gttggtgatg ttatctctca
    21721 tctgattagc ggtattgttc cttcagatag tcgctttata ggagttttgg cttatgttct
    21781 tggaatggtt ctattcacaa tgattatggg aaatgctttt gcagcattca ccgttattac
    21841 agcaggtgtt ggagttccct ttgtatttgc tctgggagct aatccaattg tggctggtgc
    21901 tcttgccatg acagcaggtt attgtgggac cttattgacc ccaatggctg ctaattttaa
    21961 cgctctacca gcagcattga tggatatgaa agatcagaat ggcgttataa aggctcaagc
    22021 aggtgttgct ctagtaatga ttgttattca catattctta atgtactttc tcgcatttta
    22081 gtaaaggaaa ataaaatgaa aatattggtt acaggtttta atccttttgg aggtgaaaag
    22141 attaatccag ctttggaggc tgtaaaatta ttaccatctg agattaatgg ggctgaagtt
    22201 cgctgggtag aaattccaac ggttttttat aagtcgtcag aagttttaga ggcagaaata
    22261 ttacgatatc aaccagatgc tgtactttgt attggacaag caggcggcag gaccggctta
    22321 acacctgaac gagtggctat taatcaagat gatgctcgca tacctgataa cgaaggcaat
    22381 caaccaattg atacaccgat tcgtattgat ggagcatcgg cctattttag tagtttacct
    22441 atcaaagcga tggtacaagc tatcaaaaaa cagggacttc cggcagttgt atccaatagt
    22501 gcaggaacct ttgtttgcaa tcatttgatg taccaagctc tttatttagt ggataaaaaa
    22561 ttccctaata tgagagcagg tttcatgcat attccatata tgatggaaca agtagtaaat
    22621 aagccgaata ctgcaggaat gagtctatgt gatattgtaa gaggcataga ggtagctatt
    22681 gaagctattg tagactacaa agataaggat ttgcagttag taggcggtga gactcactga
    22741 taacctaaaa aggatagtca attatgcttg tttactaact attaactatg ctaaatcaat
    22801 tgaggttgtt tacataaaac tctatatcag agaagcctga tatagagttt tttcttgcta
    22861 gttttaggat tttcttgtaa aatagaaaaa gtgaagagag gtatgaaatg agcaagaaag
    22921 ataaaaaaat cgaaattcaa gtagcggatg ccaaagttaa tgttggtaaa gacagttttg
    22981 aaggttatac attgactatc ggtaaaaaag ttatcggaga aattgccgaa ttagacggac
    23041 aatttgccat tataaagaat gggaatgtcg atagttttta taaaaaattg gaaaaagttg
    23101 tggaaatttt gattgaaaat tataatttag caaaataagt cttgtttttt tgaaattttc
    23161 atgatataat agtccatgtt gattgtagga gag
//
LOCUS       DAVLMQ010000028        22048 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000028 DAVLMQ010000000
VERSION     DAVLMQ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.028"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            117..281
                     /locus_tag="VXF95_001337"
     CDS             117..281
                     /locus_tag="VXF95_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HEV1081882.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIVGAAIVI
                     TVVSFFTGRK"
     gene            365..931
                     /gene="amaP"
                     /locus_tag="VXF95_001338"
     CDS             365..931
                     /gene="amaP"
                     /locus_tag="VXF95_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HEV1081883.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            943..1113
                     /locus_tag="VXF95_001339"
     CDS             943..1113
                     /locus_tag="VXF95_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HEV1081884.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            1152..1760
                     /locus_tag="VXF95_001340"
     CDS             1152..1760
                     /locus_tag="VXF95_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1081885.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            1791..1994
                     /locus_tag="VXF95_001341"
     CDS             1791..1994
                     /locus_tag="VXF95_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HEV1081886.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(2104..2382)
                     /locus_tag="VXF95_001342"
                     /pseudo
     CDS             complement(2104..2382)
                     /locus_tag="VXF95_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895264.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2580..2867
                     /locus_tag="VXF95_001343"
     CDS             2580..2867
                     /locus_tag="VXF95_001343"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HEV1081887.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            complement(3145..3915)
                     /locus_tag="VXF95_001344"
     CDS             complement(3145..3915)
                     /locus_tag="VXF95_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HEV1081888.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(3930..4765)
                     /locus_tag="VXF95_001345"
                     /pseudo
     CDS             complement(3930..4765)
                     /locus_tag="VXF95_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="formylglycine-generating enzyme family protein"
     gene            complement(4762..6237)
                     /locus_tag="VXF95_001346"
     CDS             complement(4762..6237)
                     /locus_tag="VXF95_001346"
                     /EC_number="3.1.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase"
                     /protein_id="HEV1081889.1"
                     /translation="MVQTKQPNIILIVVDQMRADVLSLNSKDKLVSTPTLDMMASVGY
                     NFENAYSPVPSCVPARAALLTGLDQDKSGRVGYQDEVPWNFTNTLPKVFKDMGYQTEC
                     IGKMHVFPSRQRLGFDHVLLHDGYLHVDRKYDKAYGSQFDYASDYLAFLKGKVGYDVD
                     LIDDGMDCNSWEARPWDKDEKLHPTNWVVSESISFLQRRDPTVPFFLKMSFEKPHAPL
                     NPPKYYFDMYMERLPQFLDLHIGNWEVLEKQIPSIYALRGKLKEDDQRRMVAAYFGLI
                     THIDHQISRFLTALKEFRHDKDTIIWFVSDHGDQLGEHYLFRKGYPYQGSIHIPSFIY
                     DPAGLIAGNRGTIKQLVKIQDIFPSLVDLAGGTTTDELDGRSVKNLLFGQYEGWRTEF
                     HGEHALGKDSSQYILTDQWKFIWFPVLNHYQLFDMKKDPHEMNDLYPSEKYQPIVRQM
                     KKKLVDFLRYREEGFVVDEELVPVELSKITPTLTKTGDSQS"
     gene            complement(6560..7915)
                     /locus_tag="VXF95_001347"
     CDS             complement(6560..7915)
                     /locus_tag="VXF95_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1081890.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGYFTAMMIGFLASIIFCKVMKKNWVIKLPDSVPPAIAKPFTSIIPG
                     FMAMYIVAILTYVFHLLSNDLLIDWVYKVLQTPLLGLSQSFFAVILMIFLNKLFWFFG
                     LHGGNVLAPIMEGLFGVAMLANLDAFQKGEPIPYIWTSGSFGAFVWFGGLGLVLAILI
                     FSRNSHYRKVAKLGLAPVLFNIGEPVNYGLPVVLNPLLFIPFVLSPVFMATVAYWATS
                     WGLVSPVTQNVTWVMPPILYGFFSTAFDWRAIILSVVCLIISVLTYFPFVKMVDKTEL
                     S"
     gene            complement(7925..8242)
                     /locus_tag="VXF95_001348"
     CDS             complement(7925..8242)
                     /locus_tag="VXF95_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1081891.1"
                     /translation="MNESNLESAMGLIMYGGEAKSNAMEAIQAAKKGDFSKANRRLAD
                     ANAALLQAHKAQTEMLTKEAQGEETSISLLMVHAQDHLMTSLTFVDLAKEVVEVYERF
                     EKN"
     gene            complement(8259..8576)
                     /locus_tag="VXF95_001349"
     CDS             complement(8259..8576)
                     /locus_tag="VXF95_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1081892.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            complement(8591..9487)
                     /locus_tag="VXF95_001350"
     CDS             complement(8591..9487)
                     /locus_tag="VXF95_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HEV1081893.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLKRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            complement(9484..10752)
                     /locus_tag="VXF95_001351"
     CDS             complement(9484..10752)
                     /locus_tag="VXF95_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1081894.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWFVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDPGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLEDCE"
     gene            11032..12210
                     /locus_tag="VXF95_001352"
     CDS             11032..12210
                     /locus_tag="VXF95_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HEV1081895.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDNYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            complement(12438..12884)
                     /locus_tag="VXF95_001353"
     CDS             complement(12438..12884)
                     /locus_tag="VXF95_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081896.1"
                     /translation="MTIRFEEKVSIENAQLVCQWSNSLGKVFQEQWMGPRIPFPLTLQ
                     ALEGVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLDSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRVQNLYQKEGFEIVQMVEAPVRKYSRLKLE"
     gene            12954..13613
                     /locus_tag="VXF95_001354"
     CDS             12954..13613
                     /locus_tag="VXF95_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HEV1081897.1"
                     /translation="MIDIYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLH
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLFYSWELLSLGQVVLITAG
                     LTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
                     FLASCALVFSVTELLILIQFASTTGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            complement(13585..14361)
                     /locus_tag="VXF95_001355"
     CDS             complement(13585..14361)
                     /locus_tag="VXF95_001355"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HEV1081898.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFIYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIKQAVAYQK"
     gene            complement(14354..15577)
                     /gene="trpB"
                     /locus_tag="VXF95_001356"
     CDS             complement(14354..15577)
                     /gene="trpB"
                     /locus_tag="VXF95_001356"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HEV1081899.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQNLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            complement(15555..16154)
                     /locus_tag="VXF95_001357"
     CDS             complement(15555..16154)
                     /locus_tag="VXF95_001357"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HEV1081900.1"
                     /translation="MTKVKICGLSTEEAVETAVSAGADYIGFVFAPSKRQVTLEEAAE
                     LAKLIPSDVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            complement(16141..16908)
                     /gene="trpC"
                     /locus_tag="VXF95_001358"
     CDS             complement(16141..16908)
                     /gene="trpC"
                     /locus_tag="VXF95_001358"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HEV1081901.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALAEERLKELYDYATVLGLEVLV
                     ETHNLAELEVAHRLGAQIIGVNNRNLTTFEVDLQTSVDLAKHFKDDCLYISESAIFTR
                     QDAERLAPYFNGILVGTALMQAENVVQRIKELQIDKG"
     gene            complement(16905..17909)
                     /gene="trpD"
                     /locus_tag="VXF95_001359"
     CDS             complement(16905..17909)
                     /gene="trpD"
                     /locus_tag="VXF95_001359"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HEV1081902.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIAQVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            complement(17920..18486)
                     /locus_tag="VXF95_001360"
     CDS             complement(17920..18486)
                     /locus_tag="VXF95_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HEV1081903.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMICDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDGRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            complement(18483..19844)
                     /gene="trpE"
                     /locus_tag="VXF95_001361"
     CDS             complement(18483..19844)
                     /gene="trpE"
                     /locus_tag="VXF95_001361"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HEV1081904.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYIVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEVMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETASVQVTKYMEVELFRY
                     VMHLTSVVKGRLLAELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            complement(20345..20422)
                     /locus_tag="VXF95_001362"
                     /pseudo
     CDS             complement(20345..20422)
                     /locus_tag="VXF95_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(21030..22031)
                     /locus_tag="VXF95_001363"
     CDS             complement(21030..22031)
                     /locus_tag="VXF95_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1081905.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
BASE COUNT         6913 a         4763 c         3700 g         6672 t
ORIGIN      
        1 aagaaattga ttttttgata ttaaaataaa aaaggagggt aggcagtgtt gtgatcaatt
       61 attgctggag gtcttattgg tctcttggca ggtaaaatca ctaaaaaagt agttctatgg
      121 gaatcatcgc aaatgtattc gctggtttag tcggggcata tgcaggacaa tctcttttag
      181 gtagttgggg tccatcaatc gctggaatgg ctttgctccc atctattgta ggtgcagcga
      241 ttgtgattac tgtagtgtca ttctttacag gtagaaagta aacttttcgc cagtaaagtt
      301 agcaaactat ttttaaatca atgacgggaa aaatagttta aatgttaaat cgaaaggatt
      361 gtatatgtca aaagcaaaga aaatatgttt cattattttc tgtattttaa tcttgacaat
      421 tttccttcct gttttgatag attatcatca agttagtgat ctaggtattc atctacttag
      481 ctggagacag aactccgtag ttgaattcta tcttgctaga tatgtctttt gggggacagt
      541 ggttctatca actttagttt tattatccat tttagttgtg atgttttatc ctaaacgtta
      601 cttggaaatc caacttgaaa ctaaaaacga tacattaaaa ttaaagaatt cggcaatcga
      661 aggttttgtt agaagtttgg tgagtgatca tagattgatc aagaacccaa ctgttcatgt
      721 aaatttacga aaaaataaat gtttcgttca tgtagaaggt aaaattcttc cttcagacaa
      781 catcgctgac agatgccaaa taattcaaaa tgaaataact aatggattga agcagttttt
      841 tggtattgag cgtcaagtaa aacttgaagt tgcagtaaaa aattaccaac caaaacctca
      901 aaacaaaaag actgttagtc gtgtgaagta aggaagtaaa aaatggaatg gcttaaacaa
      961 tatcgatatc caattatcgc tggtctcata ggcgtatttc tggcttgttt gattgtctcc
     1021 tttggcttct tcaaaacaat atttgtattg attttaggag cactgggagt tgcagctgga
     1081 ttatatatcg aaaaaaacta tatagataaa taaaaaaata aaaattacta atttaattaa
     1141 aggagtttca tatgtcaaac gaaaaaaaca caaacactaa cgtagaaaag aaagatgcta
     1201 ctgttgtagc tcacgaaatc aaaggggaac ttacttacga agataaagtt atccaaaaaa
     1261 tcattggtct ttcactagaa aacgtttcag gtcttttggg aatcgatggt ggtttcttct
     1321 caaatcttaa agaaaaaatc gttaacagcg atgacgtaac aagtggtgtt aacgtagaag
     1381 ttggtaaaac acaagttgca gttgacttaa acgttattgt tgagtaccaa aaaaatgttc
     1441 cagctttata ttcagaaatc agagaaatcg tatcttcaga agttgctaaa atgactgact
     1501 tggaaattgt tgaaatcaac gtaaacgttg tcgacatcaa aactaaagaa cagcatgaag
     1561 cagactcagt aagccttcaa gatcgcgtat ctgacgttgc tgaatcaaca ggagaattca
     1621 cttcagaaca attcgaaaaa gctaaatctg gtcttggatc tggtttctca actgttcaag
     1681 aaaaagttag cgaaggtgta gaagctgtta aaggtgcagc aaatggtgta gtatctcacg
     1741 aaaacactcg tgtaaactaa gataaaataa atataacagg agaaattatc atgtcagtag
     1801 aagaaaaatt aaatcaagct aaaggttcta ttaaagaagg tgttgggaaa gccatcggtg
     1861 atgaaaaaat ggaaaaagaa ggagcagctg aaaaagttgt ttctaaagta aaagaagttg
     1921 ccgaagacgc taaagacgct gtagaaggtg ctgtagaagg tgttaaaaac atgttgagtg
     1981 gcgacgataa ataaggttaa aagttacttt atctttttgg taacattagt caaaagagtc
     2041 tgagtcaaga tgattctcag aaaacaaaaa gctagagatt cccaattgcg gaactctagc
     2101 tttttaattt tgcctctttc tcttattata tttcagcagg ttgttggcca tgagtatgaa
     2161 tcccatgtca attctcactt gacgcttacc tctcagatga catctcttat aacccaaaca
     2221 aacctttatc tgcccaaaga cagatttcat atcaatctta cgtttagcga aaatttgtct
     2281 acccttggaa gataaaagtg cctgatattc tttagttttt aaacactggt aacgttcatt
     2341 catatacagt ctcttttgag gggctgattc aggttcataa tcgcagttaa cattgatttc
     2401 aaggctgttt gctttctatc tccccttttt catgatatat tttcgtacag gttcttcaat
     2461 agtttctata gtaaaatgaa ccaaaaatag tacacgttgc ggtataatgt tcttgtggca
     2521 tattcattag attttcgtaa acagttctct cctatttgtg agcgaacagg tatagtcaat
     2581 tgattgtcag tttgaagacc aagagtcgta aggcaaagga tatggcagaa tccatccaag
     2641 ggtggctggc acaatttcta gtgaacctct ttaaatctat tacgtttgac tgtggaaaag
     2701 agttttcaaa atggaaagat atttccaatc atcacgatag tgagagcttt tttgcgaatc
     2761 taggatgttc aagacagcgg tgtctcaacg aacattcaaa tagactttta aggtgtcatg
     2821 acttgccaaa gcagacagat ttcaacgaag tcagtcaaga attttaggct ggacaaaaac
     2881 tcaatttcag gagaaaatga aataaatatt cccacaataa aacgcatagt atcaaagttt
     2941 ttccaacacc tgatattatg cattttttaa ttttaaagac tttttcccag cctcaagaaa
     3001 tcacatccca cctaaatcct ttggatacca aatacctcat caggtatttt ctgagttggt
     3061 aagactgtct agcttaattt gacaaatgga gggcgttaaa tccagttttt acaggaagtc
     3121 tatttaaata ttttcacact gaccttacaa aatatgaaat aaattatata aagtcattcc
     3181 catgacaaag aataacatcc ctttaaaaca gtatcttacc caattttcag gtaagacttt
     3241 tgatacaacc gtccccaata cccctccgca tatagaagca agaaaaataa ctggaacagg
     3301 tgctaaatga tactgattta aacctgtaac cacaacaatt gtagccaaat gagacagctg
     3361 ggaaaagaaa ataattgcaa gagaatacat cgttgcttct tttatcgaaa tagaaaaaaa
     3421 caccatcaat aaagatacat tgagcggacc accaccaatc cctaaaaaac tagaaattaa
     3481 gcccaataga agaccacaaa tcatatagaa tcctatctta tcaaattgat aagttttttt
     3541 aaaatctgtt aaaacaaatg atacaagtag catcacaaat agtaaaatca tttgaacaat
     3601 ggatactagc cgtactgata actgagataa caaaacttga aaaataagat gacctagaaa
     3661 tcctcctaaa acagaagaaa aggataccgt aaaaatcaat ctccatttta tctctttact
     3721 ttgtgaaaat cttttgattg ttgaaataat cgccattata aaaacagaga aactagaata
     3781 aaaagcaata tcactgaccg aatggtatcc aaaactatcc ataagtggct taattataat
     3841 tccaccaccc atgcctgata tagaacccaa tccactagct attataatga ttagaaaata
     3901 aataatctca accacttttt aagtccatcc tattctttca aacatctaaa acctagatgg
     3961 ctactagtgg aagtagaaat acatccattt ctagcagcta ctcggtatcg attacaataa
     4021 gaacaatgac ataaaaagga acctcctctg atagcatact cctcatcttg tatcccatat
     4081 tttggtaact catagtcatc ttcattaaaa ctagctaata aggtatatct cggattgcga
     4141 caccattccc aaacattccc aatcatttga tatagaccaa aatcattagg taaaaattca
     4201 tagacaggag ccgttcctat aaatccatct aaggcagtat tttcataagg aaatcttcct
     4261 tgccaagtat tggcatgata atatccacct tctaaaagag tatctcccca aggatattca
     4321 gattgtcttc ctcctctagc agcatattcc cactgtgctt cagtcggtaa agacattccg
     4381 ctccaattac agaaagccaa tgcatcttct aaagcaacat gaactactgg atggtcttct
     4441 aaacccacta gattactatt ctcaccgtag ggatgtttcc agcaagcgtt cggaacttgt
     4501 aaccaccacg gagccccagc aggatgagaa tatccctccc tttctgcctc tggaacgaac
     4561 aatataaaaa caaaagacca ctctgtgttt tatagcctgt ttctttcaca aattgagcaa
     4621 attcttgatt cgtaactgga gtatccgcaa tggaaaaatc ctttacacta acagcgactt
     4681 gaggaccttc aaaatcatct aaaaagccct cttcagaatt tgttcccatc ataaatgtcc
     4741 cacccttgat ttttttcatt ttcatgattg actatccccc gttttcgtta gagttggcgt
     4801 tattttagaa agttcaacag gaactaactc ttcatccaca acaaaacctt cttctctata
     4861 tctaagaaag tctactaatt ttttcttcat ctgacgaaca ataggttggt atttttcact
     4921 tggatacaaa tcattcattt catgcggatc ttttttcata tcaaataact gataatgatt
     4981 taaaacagga aaccagataa atttccactg gtctgtcaag atatattgac tagaatcttt
     5041 tcctaaagca tgttcaccat gaaattctgt tcgccacccc tcgtactgtc caaataataa
     5101 attcttaaca ctccgtccat ctagttcatc tgtagtagtt cctcctgcca aatccacgag
     5161 tgaaggaaaa atatcttgaa ttttcactaa ttgcttgatt gttcccctat taccagctat
     5221 caatccagcc ggatcgtaaa taaacgaagg aatgtggata cttccctgat aaggatatcc
     5281 ctttctaaac agataatgtt caccaagctg atctccatga tccgaaacaa accagataat
     5341 cgtatcttta tcatgacgaa attcttttag ggcagtcaaa aagcgactaa tttgatggtc
     5401 tatatgagta atcaatccaa aataagcagc aaccattctt ctttgatcat cttcctttaa
     5461 tttccctctt aaagcataaa tagacggaat ttgcttttct aatacttccc aattcccgat
     5521 atgcaaatcg agaaattgag gcaagcgttc catatacata tcaaaatagt attttggggg
     5581 atttaatgga gcatgtggtt tttcaaaaga cattttgaga aaaaaaggaa ccgttggatc
     5641 tcttctttgt aaaaatgaaa tggactcact cacaacccag tttgttggat gtaacttctc
     5701 atctttatcc caaggtctag cttcccaaga attacaatcc attccgtcat caatcaaatc
     5761 aacatcataa ccaactttac cctttaaaaa ggctagatag tcactagcat aatcaaattg
     5821 acttccataa gccttatcat actttctatc aacatgtaga tacccatcgt gaagtaagac
     5881 atgatcaaac ccaagtctct gtctggaagg aaaaacatgc atcttaccaa tacactctgt
     5941 ttgataaccc atatctttaa agacttttgg aagagtatta gtaaaattcc aaggcacctc
     6001 atcttgataa ccaactcgtc cacttttatc ttggtctaag ccagtcaata aagctgccct
     6061 agcaggaaca caagaaggaa ctggagaata ggcattttca aaattataac ctacactagc
     6121 catcatatct aatgttggag tgctaactag cttatcctta ctattcaagg ataagacgtc
     6181 tgctctcatt tgatctacaa caatcaaaat aatatttggc tgttttgtct gaaccataaa
     6241 atctcctttc taatatggca aaagaggcac aagaagatat ctacctttac tgcacccctt
     6301 tctatatcaa tctctctata taaaacaata acattcttgt tatgttttat agaaaaatga
     6361 actaaaatat gactaaatcg attaggaaat tcaaatcatt ttctagtact gttttagaag
     6421 ttacagtgta ctattccaac ttcaataaat tataaacctt tgtctaataa caattttagt
     6481 ggagataaga aatcctacac ctaactcatc ttacacgtaa tctatttcta ttttatcaca
     6541 aaaaacgcaa gtaagaccat taactcaatt cagttttatc taccattttc acaaatggga
     6601 aataagtcaa gacactaata atcaaacaaa caactgataa gatgatggca cgccaatcaa
     6661 atgctgtaga gaagaaacca tataaaattg gaggcattac ccaagtaacg ttttgtgtaa
     6721 caggtgaaac aagaccccag cttgttgccc agtaagctac cgttgccatg aaaaccgggc
     6781 taagtacaaa tggtataaat agcaaaggat tcaagacaac tggtaaacca taattgaccg
     6841 gctcaccaat attaaacaga actggtgcta gaccaagttt agcaactttt cgataatgac
     6901 tgtttcttga aaaaattaaa atagcaagta ctaatcctaa tcctccaaac cagacaaacg
     6961 ccccaaaaga cccacttgtc catatataag gaatcggttc acctttttgg aaagcatcca
     7021 gattcgctaa catagcaact ccaaacagcc cttccatgat gggagccaat acatttcctc
     7081 catggagacc aaaaaaccag aataacttat tcaaaaagat catcagaata actgcaaaga
     7141 aactttgaga caaacctagt aatggcgttt gtaacacctt gtaaacccaa tcaatcaata
     7201 agtcattgct aagtaaatgg aaaacataag tcaagatggc tactatatac atcgccataa
     7261 atcctggaat gatagaagtg aacggcttag caatcgcagg gggaactgaa tctggtaact
     7321 tgattaccca gttctttttc attactttac agaaaataat agaggctaaa aatccaatca
     7381 tcatggctgt aaagtagcct ctggcattaa tatggtttcc tggaatcaca ttcccaatag
     7441 ttaccatcag atttttacca tcaaatgcta gattatcaat tccttgtaag atttgatcta
     7501 atttcacatc tcctacattt gccaaaggga aactctttgt aactgtactt ccaatcgaaa
     7561 tgacaaacga agcaagcgat accaaaccag cagaaactgt atcaacctta taaatcttag
     7621 cgatattcac tcccaagcaa tagatgaaca ataaggaaac aattggtata cttcccttga
     7681 ataccaaatt attgatgtca acaagccact gaaaggtttt cgtaatactt tctaggtgaa
     7741 attgttgtgg taaatccact agaaaagcat ttaataacaa agcaatggaa cctgtcataa
     7801 taacaggcat agtccccaca aatgaatcac gtaaagcaac taaaaacttc tgattcccaa
     7861 ctttcattgc aattggagaa agtttttctt gcattttatc caacattgta ttcatagcaa
     7921 attcctaatt tttttcaaat cgttcgtata cttctaccac ttctttcgcc aagtcaacaa
     7981 aggtcagact cgtcattaaa tgatcttgcg cgtgtaccat caagaggcta attgatgttt
     8041 cttccccctg tgcctctttt gtcaacattt ctgtttgagc cttatgcgcc tgtaataagg
     8101 cagcattcgc atcagctaat cttcgattgg ctttagagaa atcccctttt tttgctgcct
     8161 gaatagcctc catagcatta cttttggctt ccccaccata cataattagc cccattgcag
     8221 attctaaatt actttcattc atagcattct cctcaatctt agtctaataa actttcagct
     8281 aaatctaaga ctttagaacc attcatcatt ccataatctg tcatcggaat aaccgccaca
     8341 ggaatctgtc tatcttttag tttttcttga aagtccccta gtaaatagcg aacttgaggg
     8401 cctaaaagca acacatttac ttcttttgtt gctacaattt cttctgcttc aggagctgga
     8461 actgcaaaaa tttctgcatc caacccctta tcttctgctg ccttttgcat ctttgtcact
     8521 agcagacttg tactcatacc tgctgcacat gctaacataa ttgttacttt agccatagct
     8581 tactccttta tcacctattt actgacctag ccaagcgaga tactgtatgt ctcactcctc
     8641 taattgcctt gctcaatgca taaatattat cgactgttgc cagtccccca tatcctgcgt
     8701 cacctatatg ttgaatatca actccacaaa ttttatttct aagtgcaatt tccttaatag
     8761 tatctgtatc agatgtttct tggctagtac caatagcact caatacaaga ccacccttac
     8821 tatgaacgag atcaacgact tcacgcaact cttggtcatg aaaggctgga acggttccaa
     8881 ctgctggaac aagtatcaca tccgcacctg cttccaacaa ttgctctgcg acagaaagct
     8941 ctgccacagg ctcattcact cctgccccgt gcatcttacc tgcaataatc aaaccagaaa
     9001 agttttcctt agcagtttga acagccttaa tgatttctcg attgctaact cctgttccag
     9061 gatttccagt caaacagaca aagtcaaaac ctaactcctc tattcgcttc aatgtttcaa
     9121 cactagcaac acgacctgca acaatttcct gtgtttcctc tagcatcttt gcagatgggt
     9181 caatcggttc caaatttaca ccaattggac aagcaacaag ctggtgtaag cgatgaataa
     9241 catcatcacc tgaactatcc aaagcataaa ttttaggctc aaaaacatca acacaattca
     9301 ataaaatcat atcagctcca aaagctctag caatttcaga attagttata tccccaacaa
     9361 atgtctcacg agtaactaca ttttcagata gaacaactct accttcactt gctaaaatac
     9421 tttgttttaa ttcttcagca ttcatctgta atatctcaga tggatttgca ctaattaaac
     9481 gtttcattcg caatcctcca ataacttaaa ccgtttttca atagctatta caaatggtaa
     9541 ataaagtaag acatccaaaa caatcaatac aatttgtaat aatgaaccag aaatacttcc
     9601 tgtagcaagt aaaccactta taacaggtgg catagtccaa cctggatctg tataagttag
     9661 cggaaccaaa cctgatgcca ttgctcccca cgctactagt aagttaaaca ttggagctaa
     9721 gataaatgga actagtaaca aaatgttcaa aacaatagga acgccaaaca ttgctggttc
     9781 atttatatta aataatccag gtataacagt tataggtgcc aaagttttta gttgtttact
     9841 agctttcttc ttatgtgcta aatatcctaa cgcaagaact aaacctatgg ttgcaccacc
     9901 gccacctatg aatacaaaat tatccataaa tacgctagta aaaatatttg gaagagtttc
     9961 tccagtttga taagctactt tatttgcatc tagattagct aaccataacg gtttcataac
    10021 tgcattaaca acatttcctc cgtgtaatcc tacaaaccaa aaactactat taaggaaaat
    10081 taagataaga aggccaataa cattatttcc taaaagtcca agtggacctc ccaaagctac
    10141 ttgagcaatt tcatgaagat taggtaaact taatttatct aaagttgcat aaacaatcaa
    10201 ccaaccaaca atagtcactg caccaggaat aatggcacta aagcttttag atactgctgg
    10261 tggaacacca tccggcattt ttatctgtat attatgattt ataaaccatt ggtagatata
    10321 gccattaatc aatcctaaaa tcatagcaac aaataaacct tttgatgcca tgaaagcggt
    10381 aggcattcct gctccagcct ctcctctaat gaaaggcgta actgtaataa aagatgataa
    10441 tgacacaata ccagcaggaa taccatcaac tttgtattgt ctagccataa agtaagcgat
    10501 accaaaacta gctacaagac caagtaatcc aaaactacta tcaacaccct tccataaata
    10561 gtcagcaaca ccaatatcac ccagatattt ttcccatcct ggaataggaa aacttgcaat
    10621 aaccattagt aatgaaccta tcaacaataa aggtatagtt agagtaatac cgtctcgaat
    10681 agaaaccaac gctttattat tacccaatct agccgctact ggaagtaact tttcttgtaa
    10741 taatttttcc ataacctttt cctcttaaat atattttatt atcaaaagtt atcaattatc
    10801 tttatttttt gacgtcaagt tgttatttga ttatcttttg ttatttatat tttacaacta
    10861 taagaaagcc ttgtcaagga tttgtgtaaa catttgatta ttttttatta tcaatatata
    10921 ataaaaagag accagtaagt aatgaaaagc ttaaaaagat taacatctac atttatccat
    10981 agcaaaaaat cataggattt taagaatctg acaactagga agaaaactaa tatgacctta
    11041 tctaagaaac aattacaact aagagctaaa atactggaaa cagtttacac attaggtccc
    11101 atttcacgaa ttgaaatcgc tactaaaaca ggaataacac ctgcaacaac tagcagtatc
    11161 acaaatgatc tgattaaaga aaatattctc ttagaacttg gtgaagacga acacgataca
    11221 agcgtaggga gaaaaaaaat cctgctagac attcaagcta aacgatttta ctacattggt
    11281 tgtgaactat ctgaaaaaca tttcactttt gctttaggag ataatctagg aaatatctta
    11341 aaggaagaga aagaaattgt tactaaacag ttaatccaag aaaagggaaa tcaactcatt
    11401 aaccagacac taaagcaatt cttaaataac tgctctgatt atgaaataga agcaattgga
    11461 atcgcgctac ctggtcgcta tttagataat tataaaataa caacaaacaa tcctttatgg
    11521 caacatatcg acttagaaat gattcaatcc cactttgata agcctttgtt tttctctaac
    11581 aatgttaact gtatggctat aggtaaacgc ctatttagtc gccaacagaa tgaccctaat
    11641 tttgcttatt ttcattttgc tagaggtatg cactgttctt atatctacga cggaaacatt
    11701 tatgggaaag gaaatctaat gattggagaa atagggcata cagttgtttc atctgaggga
    11761 gaagaatgta gctgcggacg caagggatgc ttacaaactt ttgctggaga atcttggtta
    11821 atcaaaaaat caaaaattct atatcatcaa tctccctatt ctctacttcc tagtttagtc
    11881 aaaaatgccg atgatattga tatccaagtt attttaaccg cttatcaatt aggtgacact
    11941 ggaataatca cacttatcca tcaagcctta ctctatctta gtcaaaccat tttaaatatc
    12001 agtatgatga ttgactctca aaaaatctac ctacatagtc ctttactaac aaatcaacac
    12061 atcatccaaa aactatatag tgaaatgaac tacaaaccca aactgctcta taatcgccta
    12121 cctgaagtca ttattgaacc ttacaatgat tttacagccg cacactcagc tattgcactt
    12181 tgtttgtatc atacaattct acattcttaa ttttctatta catttaataa ataggctaaa
    12241 aagagggagt atatcataaa aagcgaataa acctgttttc tgaaaatcag aattctgttt
    12301 tgttcgcttt ctttatattt ggaattatac tcctatctcc cctttttcat aatgtataat
    12361 aaaatgaaat aataacagga cgaatcgatc gggacagtca aatcgatttc taacaatgtt
    12421 ttagaagtag aggtgtacta ttctagtttc aatctactat attttcgtac aggtgcttca
    12481 accatttgaa cgatttcaaa tccttctttt tggtaaagat tctgaactct ttgatttgcc
    12541 tcgaagacat ttagagaaat actatctata tcttcatttt caaaggccaa actaacaaat
    12601 ttccttaaag cttggctatc taagccttgc ccctgtttct gggggttgat aaaaaatctc
    12661 ccgatatgaa gattgctgtc ttctagcctg attttctgga taagtcccac aaactcttgt
    12721 tcatcaaaga ttgaaaagac tccttccaag gcttgaaggg tcagtggaaa aggaatcctt
    12781 ggtcccatcc attgttcttg aaagactttg cctaaggagt tggaccactg gcatacgagc
    12841 tgagcgtttt ctatactcac cttttcttca aaacgaattg tcatcttttc ctccccatct
    12901 tatctatgtt tctccattat actacttctc ccatttttta cgaatagata agtatgattg
    12961 atatttattt ttttcttgtc gggagcattc tcgcttcctt tcttggtttg gtcattgacc
    13021 gttttccaga gcaatccatt atcagttcag ccagtcactg cgattcctgt cagactcgct
    13081 tgcatccctt agatttgatt ccgattctct cacaggtctt caatcgcttt cgctgtcgct
    13141 actgcaaagt tcgctatcct gtctggtatg ccctctttga actaggctta ggactcctct
    13201 ttctgtttta ctcttgggaa ttgctttcct tggggcaagt cgtcctaatc accgctggtt
    13261 tgaccttggg tatctacgac tttcaccatc aggaatatcc cttactggtc tggatgactt
    13321 tccacctaat cctaatagct tcctctggct ggaatctggt catggtctcc ttcctcatac
    13381 ttggaatttt ggctcatttt atcgatatcc gcatgggtgc aggggatttc ctttttttag
    13441 cttcttgtgc tctcgtcttt agcgtaacgg agttactgat cttgattcag ttcgcttcta
    13501 cgacgggtat cctggccttt ctcctgcaaa agaaaaagga aagacttcct ttcgtgcctt
    13561 tcctcttact tgctacttgt ttgattattt ttggtaagct actgcttgtt tgataaagtc
    13621 ctgaatcggc tctccttggt ggagagcttt tactattttc gaaccgacga taacaccatc
    13681 tgacaccgca ttgaagcgtt ccagatcggc ttgactagat acaccaaaac ctgtcaagac
    13741 tgggatgtcg gccacttgat gaagttgcgc caagtgcttg tccaaatctg cacggtaatt
    13801 gcctgatttc cctgtcactc cattgatggc aacggcatag atgaatccct ccgccccttc
    13861 aatcaactct ttctggcgct caattcctgt ggtcaagctt actaaaggaa tcaaggcgat
    13921 atctgtatct gccaaaaatg gttctacaaa gttggcatgt tcatgaggca agtctgggat
    13981 aatcaagccc ttcacagctg tatcagccag atctttgaca aagttctcca caccgtactg
    14041 aaagaggggg ttgaagtagg tcatgatgac cagtggaatc tctgtttcaa tggttttcaa
    14101 ggtttcaact aaagcctggg tagaggtccc gtgggctaaa ctgcgcaagc cagcttcttc
    14161 gataacaggt ccatctgcaa cagggtctga aaagggaata cccacttcaa ttgcagagac
    14221 acccaaatct tctaaaaagt gaattgtttc agcaagaccg tccaaacctt tctcgtggtc
    14281 accagccatg atatagggaa caaaaattcc ttttccagct gctttaatag cattcaattt
    14341 ttctgttagt gtcttaggca tgagcttctc ccttctttgc tgcatctgct tccaagcggt
    14401 ctttgacttg aaccacatcc ttgtccccac gacctgatag gcagacaatc atagactttt
    14461 ctggtccaag ttctttggcc aatttcaccg caaaagcgat agcatggcta gattccaagg
    14521 ctgggataat cccttccaca cgagacaaga gttggaatcc ttccaaggct tcttcgtctg
    14581 tcacagggac atagctggca cgtttgatat cgtggtagtg agaatgttct ggaccaatac
    14641 caggatagtc caaacctgct gagatagaga aggcttcaag aatttgacca tgggcatctt
    14701 ggagcacatc catgagagaa ccgtgaagaa cacccggacg acccttggtc aaggtagcag
    14761 cgtggtgctc tgtatccaca ccaagccctg ctgcttcagt tccatacata gctactgact
    14821 catcttctac aaagggatgg aagagcccaa tagcattaga tccaccacca acacaggcta
    14881 ctagagcatc gggcagattt tgacctgtca tatcgcgata ctgttgttta gcttcgcgac
    14941 cgatgacact ttggaagtca cgaacgattt ctggaaatgg atgaggcccc aaggcagaac
    15001 caaggatata gtgggtatcg tcgatattag ccacccatga acgaagggct gcattgaccg
    15061 catccttgag cacgcgcgaa ccatctgtta cagcctcgac cttggctccc aaaagctcca
    15121 tgcggaagac attgagggct tggcgtttga catcttcctc acccatgtag atggtacatt
    15181 ccatgttaaa gagggccgca gcagttgcag ttgccacacc gtgctgacca gcaccggttt
    15241 ctgcgataat tttcttttta cccatgcgtt tggcaagcca aacttgtcct aaggcattgt
    15301 taatcttgtg ggctcctgta tggttaaggt cttcccgttt gagataaatc ttggctccgc
    15361 caatatgctg ggtcaagttt tttgcgtagt aaagaggagt ttcccgcccc acatactggc
    15421 gcaagagttg gtttaattcc tcttggaaac ttgggtctgc ctgactttca cgataggcct
    15481 tctccaactc caaaactgct gtcatcaatg tttctgggac aaaacgtccg ccgaattttc
    15541 cgtaaaatcc atctttattt ggttcctgat atgccatgct ttaccctctc tataaatctt
    15601 ctaatctttt catgatcttt ttgtccatct gtctccactc cgctcgatac atctactgca
    15661 tagggagtaa aatgttgaat tgcttttact acattatctt cattaaggcc acctgcgata
    15721 aagaagggct gtgctagtcc agtcgtatcc agttgacccc aatcaaaggg ctggccactt
    15781 cctgccacag gggcatcaaa gagtagataa tctgcctgag aattggggac atgcccattt
    15841 ccatctacct gcacagcctg aatactggca caaggcaaat tctcaaataa atcatctgcc
    15901 acctgaccgt gaacttgaac caagtccaag ccaactttgt caatcgcttc cagcagttct
    15961 acccgacttg gtgaaacaaa tactccaacc tttttcacat ctgaaggaat aagctttgcc
    16021 aactcagctg cctcttctaa agtcacctgt cttttactag gtgcaaagac aaaaccgatg
    16081 tagtcggctc ctgctgaaac ggctgtttcc accgcttctt cggtcgatag tccacaaatt
    16141 ttaacctttg tcaatctgca actccttgat tctctggacc acattttctg cctgcataag
    16201 agctgtccct accaaaattc cgttaaagta tggggctagt cgttccgcat cctgccttgt
    16261 gaaaatagca gattcagaaa tgtacaagca atcatctttg aaatgtttag ccaagtctac
    16321 actggtctgc aagtcgacct caaaggtggt caagttgcgg ttattgaccc cgataatctg
    16381 ggcaccaagt ctgtgagcca cttctagttc agctagattg tgagtttcca ccaagacttc
    16441 cagaccaagc actgtcgcgt agtcgtaaag ttccttaaga cgttcttctg ccaaggctgc
    16501 cacaatgagc aagatgactg tcgcacctgc attgcgagcg cggatgattt gcttttcatc
    16561 gatgataaag tccttgttga gcgtcggaat ctctacctga ctggaaatct cccgtagata
    16621 atccaaatgt cctttaaaga aaacttcatc tgtcaacacc gaaatcatca ctgctccgtt
    16681 ttcttcataa gtctgggcct gttgcacaat atccacatcg agattgatat ctcccaaact
    16741 agggctagct ttcttgacct cagcgattac ctgcaagcgg tcctgatgat tcttcaaaaa
    16801 ttctgccaag cgataggtct ggcgcagagg ctggatttgc tccagcttca tctgctccac
    16861 ctcacgcgcc ttctgctcta agattcgtgc taaaaattcc tgactcattt ttggtactcc
    16921 tgtaacagtc tgagtttttc aagggccttg cctctagcaa tcacttgacg ggccaaggca
    16981 actccttcct tgatgctatc aatcttacca ttagcataga aaccaagacc agcattcaag
    17041 actgtcgttt ccaagaatgg acttgcttcg tttttcagaa cgctaagcaa aatttctgca
    17101 ttttcctgag cattcccacc acgaatatct tccatagcat agccttccat tcccaaatcc
    17161 tctggagtaa agcttgacaa gctgatttcg ccattttcaa gaagtgcaat cttggttgtt
    17221 ccgttcaagc cagcttcatc caacccttct ggtccagcaa ccacgatggc acgtttgcga
    17281 cccatatttt tcaaaacctg agctgtactt tctaggagtt ctggacgact aattccaaga
    17341 agctgtgttt ctaaagccat tggatgaatc agtggaccag tcaagttcat aatcgttgga
    17401 attcccaatt ccaaacgagc tggcatgatg tatttcatag ctgggtgcat atttttagcg
    17461 aagagaaaga cgattccagt tttatcaaag accttaccta gttcagctgg tttgagatca
    17521 agattgattc ccaaggcttc gaggacatct gcggaaccag atttagaaga aatcgagcgg
    17581 ttaccatgct tggccatgtg aataccgcca ccagccaaga caaaggctgc agttgtggaa
    17641 atattaaaac tgaaagactt gtccccacct gtaccacagt tatccatggc atcatgaatc
    17701 tcagttggaa tatgctgggc atgtcctctc atgacttggg caatggctgt gcgttcttca
    17761 ggtgtttccc ccttcatctt gagagctaag aggagagaag caatctgcgc ttcagttaca
    17821 cgcccagtta cgatacgctc aatgacatcc gtcatttcca cacctgataa attttcaaat
    17881 tttgctagtt tttcaataat ctctttcatc ctagtttcct cactttacaa ccttctcgat
    17941 aaaattccga atagaagaca agccgtctgg cgttccaatg ctctctggat ggtactggaa
    18001 gccataaatc ggtaggtttt tatgttgaat ccccatgatg gcttggtcat cagtcgaacg
    18061 agctgtcact tcaaagtctt ctggcatttc ctcaatcaaa atactgtgat aacgcatgac
    18121 cgcacgtcca tcctcaatac cttgatacaa aacagatggc gcttcaaagt tgatattgct
    18181 ctgtttccca tgcatgactt ttggagccaa acctagctta ccaccaaaga cttctgcaat
    18241 ggcttggtga cccaaacaaa tccctagaat cggcttcttg cctgcaaaat cacaaatcat
    18301 gtcttccatc tttccagcat caactggcca accaggacca ggagaaaaga ccagaccatc
    18361 tgctttttca gcttcttcat acagcttgga atcatcattt ctcagaacct gaacttctgc
    18421 aaaattccca atgtattggg ccaagttata ggtaaaagaa tcatagttgt caatcaataa
    18481 aatcatggtc ttagttctcc aattctagtc atagattttg ctttgttaat ggtttcttgg
    18541 tattcgtttt gggcgataga gtcgtagaca atccctgccc cagcctgcac ataggctctt
    18601 tgatttttga gaatcatggt tcggatggca atggccaaat ccatatcacc cgtcgcagac
    18661 aagtagccga ttgctcctgc atatacgccc cgtttttccg tttccagttc atagatgcgt
    18721 ctcatagctc gaatttttgg tgctccagaa acggttccag caggaagcgt tgctttcaag
    18781 gcatccatgg cagtgagttc tgcaagcaaa cgtcccttga ccacactggt caaatgcatg
    18841 acgtagcgga agagctccac ctccatatac ttagtaactt ggacactggc cgtttcagag
    18901 atgcggccaa tatcgttacg ccccaagtct accaacattc gatgttctgc tgtttccttc
    18961 tcatcagaga ggaggtcagt cgccaaggcc ttgtcttctt catccgtagc ccctcttggt
    19021 cgcgtccctg caatcggatt ggttgtcacg atgccatttt tgacagaaac caaactttct
    19081 ggactagctc cgatgatttg ataatcccca aaatcataga aataaaggta attagaagga
    19141 ttagtcacgc ggagatttct gtagaagtca aatggatttc cagtaacttc tgctgagaaa
    19201 cgctggctga gtacacattg gaacatatca ccattacgaa tcaagtcgcg agcagtttct
    19261 accattacct caaacttatg tggagcgata tgcggtttga agtcaagtgg tgataaatcc
    19321 aagtcttcaa attcatttgg agcaggaatg cgtaattcct caagcacttg gttcaaggat
    19381 ttttccaagg cctcttgact gcgctcacta taaagtgcat cctctatgac atgtatcttc
    19441 tccttcttgt ggtcaaagac tatatagctc tcatagacaa agaaatgcat gtctggcgtc
    19501 ccaattgtat cctcagggat ttgaccaatt tcttcataaa gcgaaatcat atcgtaaccc
    19561 acaaaaccaa tggctccacc accaaaaggt agctctgaat ggtgctgact cttatgaatc
    19621 acttcataaa ggaaatccaa gggatcccga tcaatcactt gaccattttg ataaagaact
    19681 ccattttcaa acttaatctc aaaaacagga ttataggcta ggatagaaaa acgagctgtt
    19741 tccttgtctc tcggaatact ctctaagata accttgtgtt gcccctttaa gcgcatataa
    19801 gccaagattg gtgataagac atctccatga atgattcgtt ccattgtaat ttccctttca
    19861 gttctaattc tagttcgtag cgactgtatg aaaaatcccc acgcaaaata acttgcgtga
    19921 ggacgaaatt cgcggtgcca cctcaattat aggatttctc ctatctctca ttcctgtctc
    19981 agatatctcc tgtaacaggc tgtgcgataa agggcactcc cttgagaatg atgttttctt
    20041 ctctcgtttc agatgaaccc aactttacag ctttctctgc ttgttttcag caaccacaag
    20101 ctctctgtga gagaaagaac tgtaattttt ccatctatta ttttttagct tctagtagtc
    20161 tgcaatcgca gctaggtcct tgcctccacg accagagaca ttgatgaaga gatgttcatc
    20221 tcggtacacc tttatactct tcgaaaatct cttcaaaccg cgtcaacgtc gccttgccgt
    20281 aggtatggtt actgacttcg tcagttctat ctgcaacctc aaaacagtgt tttgagctga
    20341 cttcgtcagt tctatccaca acctcaaaac agtgttttga gcagcctgcg gctagtttcc
    20401 tagtttgctc tttgattttc attgagtatt actagctttt ttcgtattag tccagccttt
    20461 ttgtttgctt ttagtagtag gcaaggagct gtagatagaa ctcaagttca tcaaagcgac
    20521 ttaaggccct aataaaagat aaaccaaacg acggatagaa aaaagcccac acacagaata
    20581 tacttccgtg tgagggcgtt ggtaacgcga tgccacctca attataaagg gactatccct
    20641 ttacatctct gccttgttta acaacaagct gcactgtaag gtgtgcgcac cgaattttca
    20701 ttgtttcaaa ttcattttca aaatcagccc actttcacta cttccaacca cctattcaca
    20761 atcaccacag gctccctgaa gatcaaaaat agttactttt ctgatttgtt gaacttattt
    20821 taatactttg ttttttcttt gtcaagactt ttttacgatt tttttgaaaa tatcattcga
    20881 atgtgaccat gtcttcctta gatcgaacat gaacatgtcc cactcgttag aaattggatc
    20941 caactcaata gaaactgaat ggaggctaaa cagaacttat tttagaacac tccatctttt
    21001 ccactaggat tttcaagaat taaacaatac tagaaactct gtctcctaac aaatttagga
    21061 gaaacttcaa cagatgtgac actttcccct ttaataattg ctaaaacacc ttctatcatt
    21121 tctttagcca atttaacata attgggagca attgtagaca aagctggagt ataatactga
    21181 gaaataggaa tattatcaaa tccaatgata gaaatatcat ctggaataag aattcctttc
    21241 tcatagcacg cacgaatcaa gccctgaacc ttttcatctc ctgaaacaaa aataatgtcc
    21301 ggataatttt gggtagtcaa gtgctgcatt gcataagaat aaactgaatc aattgtagat
    21361 aagccataaa tgacttttaa atccataaag taatttttat cattcagaaa agaacgcaca
    21421 cctctttcac gatccttatt aacatgggat tctcctccca taagcaacca catattttta
    21481 aatttttctt cagttacagc tttcatcata tcataagtag cttgaaaatt attattagat
    21541 acatagacta ctccagacgt ttgagattca ccgaaaacaa gaaaaggcat atggttcttc
    21601 tttaaatact gaattctgat atcatctaca ctttcataaa aaacaataac accatctact
    21661 aggctacctg tgcttgatat aattgaatta ctaattgtat cctcctctcc aaagtactca
    21721 actatagcat taacaccaaa ttctttacac gtccgtaaca ctttatctaa cagcgtatga
    21781 aaccaaatta aaggaaaaga gtcgattttt tttacagaaa tcaatatatt tatagcttct
    21841 tttttagtta aattttttgc atacgcattt ggaatatacg acaattcctc tataactttt
    21901 tgaatcgctt gataagtttc ttctttaaca tttactccac cattaataac tcgtgaaact
    21961 gtttttggag aaaaacctga taaacgtgca atatcataaa tagttacctt tttcccattt
    22021 atatttttca tttcagtcct ccattacg
//
LOCUS       DAVLMQ010000029        21156 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000029 DAVLMQ010000000
VERSION     DAVLMQ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21156
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.029"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(85..984)
                     /gene="galU"
                     /locus_tag="VXF95_001364"
     CDS             complement(85..984)
                     /gene="galU"
                     /locus_tag="VXF95_001364"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HEV1081906.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            complement(1006..2022)
                     /locus_tag="VXF95_001365"
     CDS             complement(1006..2022)
                     /locus_tag="VXF95_001365"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1081907.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     HHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKVI
                     IMHASKGLEPDSHKRLSTILEEEIPEHLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQKLFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            2234..2614
                     /locus_tag="VXF95_001366"
     CDS             2234..2614
                     /locus_tag="VXF95_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HEV1081908.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            complement(2788..3213)
                     /locus_tag="VXF95_001367"
     CDS             complement(2788..3213)
                     /locus_tag="VXF95_001367"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1081909.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMIGCLAYNLYLFLKQLAGDEVKSLTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(3281..3931)
                     /gene="phoU"
                     /locus_tag="VXF95_001368"
     CDS             complement(3281..3931)
                     /gene="phoU"
                     /locus_tag="VXF95_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HEV1081910.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKTLLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            complement(3946..4698)
                     /gene="pstB"
                     /locus_tag="VXF95_001369"
     CDS             complement(3946..4698)
                     /gene="pstB"
                     /locus_tag="VXF95_001369"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HEV1081911.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWDEVKDNLKKSAMSLSGGQQQRLCIARA
                     LAVEPDVLLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            complement(4700..5515)
                     /gene="pstA"
                     /locus_tag="VXF95_001370"
     CDS             complement(4700..5515)
                     /gene="pstA"
                     /locus_tag="VXF95_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HEV1081912.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            complement(5508..6371)
                     /gene="pstC"
                     /locus_tag="VXF95_001371"
     CDS             complement(5508..6371)
                     /gene="pstC"
                     /locus_tag="VXF95_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HEV1081913.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFIANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRSFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            complement(6489..7364)
                     /locus_tag="VXF95_001372"
     CDS             complement(6489..7364)
                     /locus_tag="VXF95_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HEV1081914.1"
                     /translation="MKFKKMLTLAAIGLSGFGLVACGNQSAASKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            complement(7531..8862)
                     /locus_tag="VXF95_001373"
     CDS             complement(7531..8862)
                     /locus_tag="VXF95_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HEV1081915.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGQGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQEQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            complement(8863..9570)
                     /locus_tag="VXF95_001374"
     CDS             complement(8863..9570)
                     /locus_tag="VXF95_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1081916.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGMEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGEQEGDDSDNIADDSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            complement(9654..10130)
                     /locus_tag="VXF95_001375"
     CDS             complement(9654..10130)
                     /locus_tag="VXF95_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HEV1081917.1"
                     /translation="MDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALYTSI
                     YFLLEETNPSHFHRLTADEIWYFHAGSPLTVHMITADGHYEAVTLGLDISKGQQLHYC
                     VPKSTIWGSTVDKDYALVSCLVAPGFEFEDFELFERADLLATYPEHKEMIEHLTRY"
     gene            10137..10683
                     /locus_tag="VXF95_001376"
                     /pseudo
     CDS             10137..10683
                     /locus_tag="VXF95_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11073..12764)
                     /locus_tag="VXF95_001377"
     CDS             complement(11073..12764)
                     /locus_tag="VXF95_001377"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HEV1081918.1"
                     /translation="MNTKELIASELASIIDNLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            12900..13346
                     /gene="argR"
                     /locus_tag="VXF95_001378"
     CDS             12900..13346
                     /gene="argR"
                     /locus_tag="VXF95_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1081919.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDEWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            13397..15931
                     /gene="mutS"
                     /locus_tag="VXF95_001379"
     CDS             13397..15931
                     /gene="mutS"
                     /locus_tag="VXF95_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HEV1081920.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDCEGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            16078..17772
                     /gene="patA"
                     /locus_tag="VXF95_001380"
     CDS             16078..17772
                     /gene="patA"
                     /locus_tag="VXF95_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HEV1081921.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDKEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQEGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(18102..18371)
                     /locus_tag="VXF95_001381"
                     /pseudo
     CDS             complement(18102..18371)
                     /locus_tag="VXF95_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019770457.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            18563..20329
                     /gene="patB"
                     /locus_tag="VXF95_001382"
     CDS             18563..20329
                     /gene="patB"
                     /locus_tag="VXF95_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HEV1081922.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTHVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMSNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMGLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            20468..>21156
                     /locus_tag="VXF95_001383"
     CDS             20468..>21156
                     /locus_tag="VXF95_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1081923.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
BASE COUNT         6149 a         4156 c         4553 g         6298 t
ORIGIN      
        1 ttcattagtt tttattaaat aggtagattc aagtagagaa tttacttaat ttatgtgtgg
       61 ctaatcttta tataaatgat tttgttattc cttctcagtc aattcttttc caagttggat
      121 gaggtaattc ttcaaatcat ctttgacttg tggatgtttg agggcgtagt cgatggatgt
      181 tttcatgaag ccaaacttgt ctccgacatc gtaacgagcc cctttgaact cacgagcaaa
      241 tacacgttgt gttttattga gggtgtcgat tgcatctgtc agctgaattt catttcctgc
      301 acctggagct tgcttttcga gaatctcaaa aatttcaggc gtgaggaggt agcgtccgat
      361 aatagcaagg tcgctaggag cgtcctctgg agctggtttt tcaacaaagg tttcaacact
      421 gtaaagacca tcttttcctt cgccttgcgg agcaataacc ccgtaagcag atacttcgtc
      481 atgagggact ggcatgacag cgatagtaga cgcgtgggta cgctcgtagt catccatgag
      541 ttgtttggta agtggaacag ccttttcgtc tgtgatatcc atcaagtcat caccaagcat
      601 aacgacaaaa ggttcatttc cgacgaaagc cttggcttgc aaaacagcat ctccgagacc
      661 gcgtggatga gtttggcgga taaaatgcag acgcatgcca gttgtttcat caactagctt
      721 caaaagatct gttttccctt tttctttgag gttatattcc aattcgaagt ttgaatcaaa
      781 gtggtcctca atagaacgtt ttgatttacc agtgacaact agaatatctt caatacctga
      841 tttgagagct tcttccacga taaactggat agttggtttg tctacgattg gcaacatttc
      901 tttggcaagg gccttggttg ctggtaaaaa tcgagttcct agtccagcag cagggatgac
      961 tgcctttcta acttttgatg tcataaaaat cctttctata gagggttaag accactcatt
     1021 ttctgcttta aattcattgt tcatgatgtc ataaatggca tctttgatat tggttccgtg
     1081 ataaataact tggtaaatag cctgtgtaat gggcatatag actccaagtt cttgggctag
     1141 ttcataggct gctcgagtcg ttgaaattcc ttcgattacc atgcccatat tagcttctat
     1201 atcagctagg gattctcctc gtccgagagc atctccagct ctccagttac gagagtggat
     1261 ggaagttccc gttacgatca aatctcccac accagataag ccgctatagg tcaatggact
     1321 ggccccgagt gctaccccta ggcgggtgat ttctgctaaa cctcgagcga tgatggctgc
     1381 cttagcatta tcaccaaatc caagaccatg taaagctcca gcaccgacag caataatatt
     1441 tttaagagca ccagcagttt caaccccgat aacatccgta ttggtataaa gtcggaagta
     1501 gtgattacta aatagcttct gaacgtattg agctgtttgt aaatctttag aagcagcagt
     1561 tattaaagtt aggtcacgca caatggtctc ttctgcatga ctaggccctg aaacaacgac
     1621 gatatcacta cggagatgtt caggaatttc ttcttcaaga atggttgata atcgtttatg
     1681 gctatcaggt tctaatccct ttgatgcgtg catgatgata accttatggt ccaaggtttg
     1741 tgcaacttgc tgggcaacaa gtcgtgtcac ttttgttggg acaacaaaca aaatcgcatc
     1801 cacatctttc aatgtttctg ctaagtcggt gtaggcaatg atattttcgt ctagaacgac
     1861 atctttaaag tagtgcttat tagtatggtg tgtattaatt tcattgattt gctcgggaag
     1921 atttccccaa atacgtacct cgtgtccatt gtcatttaag acttgtgaaa gggcggttcc
     1981 ccaagaacca ggccccaaga cggcgacggt ttgtttttcc atgatttcct ccttgataga
     2041 gttctttctc ttattctatc atattctagg ggattttgca cttgcattac tggggtatgg
     2101 tggaaaaata cacaaaaacc gagacgaagg gataaactct tagtctttag ttaaagtgag
     2161 aagaaatctg atagatagtt tgattcagta tatgcttata atagaggtaa acaactcagg
     2221 aggttcttgt aggttgcgag agtttggcga aaaaattaaa agattacgtt tggctaaaaa
     2281 aatcagtcgt tcagaatttt gtggtgatga gtctgaatta agtatccgtc aattaattag
     2341 aattgaaaat ggagaatcca gaccaacact aacaaagtta aaatatatcg ctgaacgttt
     2401 gggggttgag gattacaagt tgatgccaag ttatatagag ttggataagg aatacctaga
     2461 attgaagtat tttttgatga ggactcctac atacgaagat gaaactatcg cccaaaagaa
     2521 agagagtgtt ttgataagat ttttgaagag tattatgata ggctacctga ggaagaaaga
     2581 tttatcatcc caaattattc atatctggca ctaacgaact acacagttca aaaattacca
     2641 gaaaagctag ttgaaatact gtccttctgg tgattttgct taatttctga tgttcgagac
     2701 ataattgagg agatttgtct tgattttttc ctaaaaaagg gcagacttct cccttggttt
     2761 gatgctcgat ttttaaaata aggtgactta ttctgttagg catgttttcc cctgccctct
     2821 agctctatat ggaacaggga gtatcagatt tatctggcag attgtatcaa ataaggcttg
     2881 aaactgtttt gaataggcgt atagacttga gaatttgaga atatgtcgtc tagcagtaga
     2941 gacatatttt ccggcaatat gaaggaagag acgtcgaaaa cgcttgatag tcaaggactt
     3001 tacttcatca ccagctagct gttttaaaaa gaggtagaga ttataagcca gacagcctat
     3061 catcatacgt acttcattct taatcatggt cgaactatct gtcttatccc caaagaatcc
     3121 tgctttcctt tctttgataa agttttcagc attccctcgt tcacgataga attgaaacag
     3181 ctcctcacta tctacactgc ttaaattggt caaatgaact tttttacaac cataaaaaag
     3241 agcacttaat cgtactcttc tcttttaagg attagttgaa ttaattcaaa tccactagtt
     3301 ctcctgtttc taggtagact aggcgttcac aaatgttagc aatgtaatca gcgaagcgtt
     3361 ccagatgccc tatgatataa aggtattgtg ttccattggg aattgaggtt tcttggtctt
     3421 tcataagtcc aatgatttcc tttgataagg cataataata ttggtcaatc tgttcatctt
     3481 tttgagcaat actaatagct tttgaggctt ggtgcaaagg aaaggcaacc aataaatcgg
     3541 atagcatgct gagggataat ttacccattt ggtgtaactg ttcttcgtca ggggctagtt
     3601 gattttcttt tagttgcaaa acagctttag caatgcctgc catatggtct cccatacgtt
     3661 caaggtctga acaagaagac atgatgctaa tcacaaatcg aaggtcagac acttgtggct
     3721 gctgcaaggc caacaaacgg gcacaggtca attcgatagc gctttgacct tggttgatag
     3781 catgatcctt attgataatt agctctgcca tctccttgtc tttggaggct aaggccagta
     3841 aggtttttga agctgtttca aggacaagtt gccctagtcc taaaaaggat tgttctaatt
     3901 catgcaattc taagtcaaat tgatttctca taggtttttc cttccttatc cgaaccgtcc
     3961 tgaaatatag tcttctgtgc gctgatcttt tggattggta aacacgtcaa cggtgtctcc
     4021 aaattcgcaa atttctcctg ttaagaaaaa agcagtttta tctgaaatac gtgaagcttg
     4081 ttgcatgtta tgggtaacaa tgataatcgt ataatccttt tttagttgct gaatgaggtc
     4141 ttcaattttt aaagtggaga tagggtctaa ggctgaagtc ggctcatcca ttaacagaac
     4201 atcaggttct actgctaaag ctcgcgcaat gcaaaggcgt tgctgctgac cgcctgataa
     4261 ggacatggca ctctttttaa gattatcttt gacttcgtcc caaatggctg ccccttttaa
     4321 agatttttcc actaaggcat ctaattgttt tttgtctcga ataccatgtg tccttgggcc
     4381 ataagccacg ttatcataga tagacatggc aaagggatta ggctgttgaa aaaccatccc
     4441 tacacgcttg cgtagctgat taaggttgaa tttgctacta taaatatctt gctcatctaa
     4501 gaggacttgg ccttcaatat ggcaagaagg aaccaaatcg ttcatccgat taagggtttt
     4561 tagaaaagtt gatttgccac aaccagatgg gcctatcaag gcagtaatct gtctttctgg
     4621 taattgaatc gaaatatttt ttaaggcttg aaaatccccg taaaataagt ctaggtgtct
     4681 gactgaaaat gttcccatac taggaagctc ctttcacaag tttccgagat aataagcttg
     4741 atagagtatt tatcattaaa acagtaataa tcaaaatcac gccggtagca taggcttcat
     4801 tgacatgtag cccctcactt gacagcatat acatatgtag ggctagagaa cggcctgaag
     4861 acatgagact acttggcgta ttggtagagg tacctaatgt atacatgagg gcagctgttt
     4921 caccaacgat acggccaata gctagtatca ctccagctaa aatacctggc atggcaactg
     4981 gtagaacaat tctaaaaaca gtccgtaact tacctgcccc aagtccataa cttgcttgac
     5041 gcatactatc actaacagat aaaagggctt cttctgttga gcgaataatg actggcaaca
     5101 ccatgataac tgaggttaag attcctgata acagagagta ttgaaaacct aagaagacta
     5161 caaagaagag catgccaaac agaccaaaaa caatggaagg aatcccagat aaggtatctg
     5221 aggccaatcg catgatttta acacaaaggg aatctttttt tgtatattcc acaagataaa
     5281 aaccagcaaa aatccctatg ggcaaggcta aaagaagagc accaaagacc agaataacgg
     5341 tggaaataat cgctggcata agggaaatgt tctcagaagt ataagtccaa gaaaagaggg
     5401 atagacttag atgaggtaag cctttgatga ggataaaacc aatgattaaa aagagagagc
     5461 caaaggttaa agctgaaaaa caataaacga gaagttttag caggtattta ctcataagat
     5521 gattttcctt tcaagtaggc aaagtaggca ttaatcaaga gaataaggaa aaagagaact
     5581 gctgaggttg caataagggc ttccctatgc tgacctgatg cgtaagccat ttccagaaca
     5641 atattggttg ttaaggttct ggttcctgaa aagagtccac ttggaataat cggctggttg
     5701 cctgccacca aaataactgc catggtttca cctactgcgc gaccgattcc taaaataact
     5761 gctgataaaa taccagatct cgcagctggc aagatgacac taaaaatact ccgttcatga
     5821 ctagctccta gagccaagct accagaataa tacgttttgg gaactgttcg gatagcagat
     5881 tctgacaaac tgataatggt tggcaaaatc attattccta atagtaacga agcggttagg
     5941 acactcatgc catttcctaa aaagcttcta atccaaggca ccaataattg taggccgaaa
     6001 aaaccataaa caatagatgg aatggctgcc atcaagttga tagctgattt taagaagcca
     6061 tagacgggct ttggacaata ataaaccata aacaccgatg tcaagatgcc tgttggcacc
     6121 ccaatcacaa tcgctcctaa ggtaattaat aaggaaccaa cgatcattgg taaaatacca
     6181 tagcttgccg gaatgttcgt tggcgaccaa tcactgccta ataaaaaacg ggcaaagccg
     6241 tagttagcta tgaaaggtaa gccattacta aaaataaaga aacagattag caaaatagct
     6301 acaacagcta ctgttgcact catgaaaaaa attgccctaa aaactgcttc tttgaaggct
     6361 tgttttgtca catcttgtcc tttctagtga agaaagtaag ggagatacga cacctcccta
     6421 cttgccttct ttatcttatt gtacgatgaa acgtctgcat ctctttagag atttatggag
     6481 caaacatttt atttaatctt gtcccaggtg gttaatttgc cactaaaaac gtctgcaagt
     6541 tcagccatac tgacttggct tgccttattg tcattattga ccacaacagc aataccgtct
     6601 aaagcaatag catcatgggt gagactctta ccttcttcag gagttaattc cctagaaacc
     6661 ataccaatat cagcggtttt ctccttaaca gcggtaatac ctgctgaaga cccattagag
     6721 gtaatatcaa tcgtaacttc tggattttct tttttataag cttctgctaa tttttccatt
     6781 aaagaagata ctgaagtgga acctacaaca gacaacttgc ctgataagtg ttggcttgta
     6841 tattctgtgg tttcggtttt agcttcaata aatttattat cagtgaccac ttgttgacct
     6901 tgtttggagt ggataaagct gataaaatct tgacctagct tggaaagatt agaagaccaa
     6961 acaatgttga agggacgttg aagagggtat tcaccatcta aaactgtgtc tcgactagcc
     7021 ttgacaccat caatctctaa agccttgaca gatttcgtta aagatcccaa ggagatgtag
     7081 ccgatagcat tagcattccc ttgaactgct gagagaacac cttctgtact attttgaatc
     7141 acagctgttt tggcagtgtt gtcaattttt ttatcaccgt cttttttgag aatccctgtg
     7201 atttctgtga aggcaccccg tgttccagag ccattttctc gtgaaatcac ctcaatcgtt
     7261 cctgaagctg actgtttgga agcagctgac tgattgccac aggcaacaag cccaaatcct
     7321 gataagccaa tggctgcaag agtaagcatt tttttgaatt tcataataat cacctttatc
     7381 tctatgtatt tttcttgtgt aggcttacta catttatagt ctaacaagtc tttgtaaagg
     7441 tttatccctg attcatgtaa agattgtgta aagaatcaaa aaaagccact tttgaaaaat
     7501 ggctgctcct aaaaatagct ttaaaaatta ttagtcctgt gcgaaagatt ggttaggaag
     7561 aaaaatcgtg aagcaactgc ctctgccaag ctgactcgtc accgtgactt ggccacctaa
     7621 taattgactg agttctttga caatggcaag gccaagacca gtgccaccag tttgtctgct
     7681 tcgaccttta ttaactcggt aaaaacgttc aaaaatacga tcctgctcta attgactaat
     7741 accaatccct gtatctgata cagaaatctt aatgccttcg ttcacctttt gggtcttgac
     7801 ctcaattttt cccccttgtt cagtgtaacg gatggcattg gataaaagat tgagtaagat
     7861 ttgggaaagt aattgactat ctgatacgag ggtgacatca tctggcacct gcacctttag
     7921 ctgtaaatcc ttcttcttga gctgaggttg caagctttga gtcaaatcct gtacaaattc
     7981 tgccaaagaa agggtcgtcc attgtatagg catttgttga gccttagata aggtaagaag
     8041 atgctcaaca atatgctcaa gacgcaagct ttctttgtaa ataatgtcta gaaagtcatc
     8101 cttgagcgct tcttcttcag ctgacatccc cttaatggtt tcagcaaagc ccttaatcga
     8161 agtaactggt gtcctcaatt catgggaggc atttgagaca aaggctaaat ttaacttttc
     8221 ataagttcta atcgttgtta aatcatatag caagacgagc acagcttcca cagattgggt
     8281 ggggctaaaa acgggaactg ctgtcacttc taaaatcaag tcaccctcat gaaacccact
     8341 tacttcttgt tttaaccttg ttttttgatc aaaggcttgg tgaactaaat ttcgaatatc
     8401 catccgtttg aggtcatcaa gtgaacttat gtcgccgtcc acatcgggaa aataatgagg
     8461 cagagagcga ctggataata acatctgacc ttgagcggaa actaaaaacg tccccatggt
     8521 taggtgcgac agaagaacct ccattgtttc ggctaggtcc ttgtattgct gttcctgttg
     8581 ggagactttg gtttttaggc cagacacata ctgagccaaa gactttaagt cttcttgccc
     8641 tttttctaaa aagtattcac tactggtcaa gagaggttgg tgcaaggtct caaaagcaac
     8701 ttcccatttc caaaggcaaa agagccagta gccaccttgt cccaaagaaa gggctagaag
     8761 aaagagaccg atgcctttac tgatccaagt taatgccatc cctgcaatca gaatgaggct
     8821 aacacttaga ttgactagcc aaaattgaag gtagcgtttc atctataact ccttgaactt
     8881 ataaccataa ccccgaatgg ttcgaataaa ttgaggggct ttaggattgt cttcaatttt
     8941 ttccctcaac ttaccaatat gaacgtccac caaacgtgtt tcctgcccaa agtcataccc
     9001 ccagatacgt tccaaaagac gctctctagt tagtgtcatg ttgggatgtt tcataagata
     9061 gagcaagagt tcaaattctt ttggggtcaa actcagtaac ttattcgcct tgtagacttc
     9121 atgacgctca gggtatactt tcaaggtccc aaatagccaa gaatcgtcag cgatattatc
     9181 tgaatcatct ccttcttgtt ctcctttagt tcgcctgagg acagccttga cacgcgccag
     9241 caattctcta gggctaaaag gcttggtcag gtagtcatca gcccctaatt ccaaggccaa
     9301 aaccttatca aattcatcac ttttcgcaga aaccatcata attggagttt tgacgccttt
     9361 ggctctcagt cgcttacaaa cttccatgcc atctaattgt ggtaacatga tatcaagcaa
     9421 gataaaatca aagggttctg tttctgccaa agctaaggcc ttccgtccat ttgttaccaa
     9481 ttgagtagaa aagccttcct tacttaaatg gtagtcaagc aatttcagaa tgtgttcttc
     9541 atcatccact aataagactt gttttgtcat ctattatctc ctattggtaa cattataaca
     9601 caattatcag aaatcctaac attgctaaat tagattaaat ttgcttatca agactagtat
     9661 ctggtcaaat gctcaatcat ctccttgtgc tctggatagg tcgccagtag atctgccctt
     9721 tcaaataatt caaaatcctc aaattcaaaa ccaggagcaa caagacaaga aaccagagca
     9781 taatccttat caactgttga tccccaaata gtgctcttag gaacacagta gtgaagttgt
     9841 tgccctttgg atatgtccag gcctaaagtg actgcttcgt agtgaccatc tgctgtaatc
     9901 atgtgaacag taagtgggga tcctgcatga aaataccaga tttcatctgc tgtcaatcgg
     9961 tgaaaatgtg aaggattcgt ttcttctaat aagaaataaa tactggtata aagcgccctt
    10021 cccttaccag caaggtttat agtgtctgaa gctttttttg tttgtctaaa atagccacct
    10081 tcaacatggg gagctaactc tagagttctt atcaagtctt ctttatccat cggggccaat
    10141 gggttgaagt aactcttgtt caaagtggtg ttacgatttc aagaactcct ctcagttctg
    10201 aggacacggt aatgattgat gcgacggaag tacaaatcaa tcgccctaaa aaaagaatta
    10261 gcgaatgatt ttggtaaaaa gaaatttcac gctatgaagg ctcaagcgat tgtcacaagt
    10321 caagggagaa ttgtttcttt ggatatcgct gtgaactatt gtcatgatat gaagttgttc
    10381 aaaatgagtc gcagaaatat cggacaagct ggaaaaatct tggctgacag tggttatcaa
    10441 gggctcatga agatatatcc tcaagcacaa actccacgta aatccagcaa actcaagccg
    10501 ctaacagctg aagataaagc ctataaccat gcgctatcca aggagagaag caaggttgag
    10561 aacatctttg ccaaagtaaa aacgtttaaa atattttcaa caacctatcg aaatcatcgt
    10621 aaacgcttcg gattacgaat gaatttgatt actggtatta tcaatcatga actaggattc
    10681 tagttttgca ggaagtctat tatttggtta ggtgaattag tgaagcgttt aggcaagtgt
    10741 ctctggttac gacgtaaaga agcataaatc gatcatattt atgtttcttt actagtgaaa
    10801 cgcctagcca aattaccata gttacgacgt catgacctct aaatcgatta tatttagggg
    10861 tcatgactag tgaagcagtt agctagttcg catataagcg gctagcgtct aacaattagg
    10921 aactttagtt ccaataactt taagattacg acgttttagg acataaatcg atcatattta
    10981 tgtcctaaaa ctagtgaagc gcctagccaa agtccgaata ggatttggcg ttagttactt
    11041 agattgcttt gcaatcaagt aactttggcg atttacatct tctctggcgc ttctactcca
    11101 agcaagcgaa gggcttcttt gagaacgact gcggttgcgt agctgagggc tagacggctg
    11161 tcgcgttctg ggctttcatc caagatacgt gtatgtgcat agtatttgtt aaaggattga
    11221 gctaggctaa ttgcaaattt agcaatgata gaaggttcaa agttatctgc cgcacggttg
    11281 ataatacgtg ggaagtcttg aatgagttta atgatttccc agctttcagt atcattcaag
    11341 ctatagttgc cagctgtttc tggtttgaaa tcggctttgc gtaagataga ttggatacga
    11401 gcgtaggcat attgaacgta aggtccagtt tcaccctcga aggataccat agcctctagg
    11461 tcgaagtcgt atccatttgt acggtcggtt ttgaggtcat agaatttaat ggctccaacc
    11521 ccaacagcat gtgctacttg gtctttgttt tctagttcag gatttttagc ctcgatttgg
    11581 accttggcac ggctaacagc ctctgcaaca gtaggctcta gcaagatgac attcccttta
    11641 cgagtagaga gtttcttccc ttcttttgta accaaaccaa aaggaacgtg agtaatgtcg
    11701 tcactccagt cgtagcccat ctcttgcaag acagctttga gctgtttaaa gtgggcagat
    11761 tgttcttgac caacgacata gatagattta gcaaattggt attcgttttt acggtaaagg
    11821 gctgcagcca agtcacgtgt gatatagaga gttgcaccat cagatttctt gatgagagct
    11881 ggatgttcaa ttccgtattt ctcaagattg acaacttggg caccttctga ttcaagaagt
    11941 agtccttttt cagaaagaat gtctacaact gcatccatct tatcattgta gaaggcttct
    12001 ccgttatagc tgtcaaattc aaccttcaat tcattgtaaa ggcggttaaa ttccactaaa
    12061 ctttcatcgc ggaaccattg ccaaagagcg agagcttcct catctccatt ttcaagttta
    12121 cggaaccatt cgcgcgcttc ttcatccaag ctagggtcat tttcagcttc agcgttgatg
    12181 cggacataga gtttaaggag ttcatcgatt ggatgagctt ttacagcttc ttcgtcgccc
    12241 cattttttgt aggcaacaat caacatccca aattgtttac cccagtctcc caaatggttg
    12301 accttgaccg tttgataacc gattttttgg aaaatatgtg acaagctatc tccgataaca
    12361 gttgaacgca ggtggccaat agaaaatggt ttagcgatat tcggactaga catgtcgata
    12421 acaacatttt cttgtttgcc aatattttgg tcagcatagt gttctttttc agtggtaaca
    12481 gcttgcaata cttgagcaga aatggcagat ttatcaagga aaaagttaac gtaaggtcct
    12541 gttgcgacaa ctttttcaaa ggcttggctg ttcatttttt cagccagttc agccgcaatc
    12601 atttgtggtg ctttacgttc gactttggca agagaaaaag cagggaaagc gatgtcaccc
    12661 atttctgagt ttttaggggt ttccagtaac tttaaaatag cctcttggtc caggttatca
    12721 atgatgctag ccaattcgct agcaatcaat tcttttgtat tcattaagag ctcctttttg
    12781 gacttttcta ctattttaac acaattttaa agaaagaaga aaaaattttt gaaatctcct
    12841 gtttttttgg tataatatgg ttataaatat agttataaat atgcacgcaa gaggatttta
    12901 tgagaaaaag agatcgtcat cagttaataa aaaaaatgat tactgaggag aaattaagta
    12961 cacaaaaaga aattcaagat cggttggagg cgcacaatgt ttgtgtgacg cagacaacct
    13021 tgtctcgtga tttgcgcgaa atcggcttga ccaaggtcaa gaaaaatgat atggtgtatt
    13081 atgtactagt aaatgagaca gaaaagattg atttggtgga atttttgtct catcatttag
    13141 aaggtgttgc aagagcagag tttaccttgg tgcttcatac caaattggga gaagcctctg
    13201 ttttggcaaa tattgtagat gtaaacaagg atgaatggat tttaggaaca gttgctggtg
    13261 ccaatacctt attggttatt tgtcgagatc agcacgttgc caaactcatg gaagatcgtt
    13321 tgctagattt gatgaaagat aagtaaggtc ttgggagttg ctctcaagac ttatttttga
    13381 aaaggagaga cagaaaatgg cgatagaaaa gctatcaccc ggcatgcaac agtatgtgga
    13441 tattaaaaag caatatccag atgctttttt gctctttcgg atgggtgatt tttatgaatt
    13501 attttatgag gatgcggtca atgctgcgca gattctggaa atttccttaa cgagtcgcaa
    13561 caagaatgcc gacaatccga tccctatggc gggtgttccc tatcattctg cccaacagta
    13621 tatcgatgtc ttgattgagc agggttataa ggtggctatc gcagagcaga tggaagatcc
    13681 taaacaagca gttggggttg ttaaacgaga ggttgttcag gtcattacgc cagggacagt
    13741 ggtcgatagc agtaagccgg acagtcagaa taattttttg gtttccatag actgcgaagg
    13801 caatcaattt ggcctagctt atatggattt ggtgacgggt gacttttatg tgacaggtct
    13861 tttggatttc acgctggttt gtggggaaat ccgtaacctc aaggctcgag aagtggtgtt
    13921 gggttatgac ttgtctgagg aagaagaaca aatcctcagc cgccagatga atctggtact
    13981 ctcttatgaa aaagaaagct ttgaagacct tcatttattg gatttgcgat tggcaacggt
    14041 ggagcaaacg gcatctagta agctgctcca gtatgttcat cggactcaga tgagggaatt
    14101 gaaccacctc aaacctgtta tccgctacga aattaaggat ttcttgcaga tggattatgc
    14161 gaccaaggct agtctggatt tggttgagaa tgctcgctca ggtaagaaac aaggcagtct
    14221 tttctggctt ttggatgaaa ccaaaacggc tatggggatg cgtctcttgc gttcttggat
    14281 tcatcgcccc ttgattgata aggaacgaat cgtccaacgt caagaagtag tgcaggtctt
    14341 tctcgaccat ttctttgagc gtagtgactt gacagacagt ctcaagggtg tttatgacat
    14401 tgagcgcttg gctagtcgtg tttcttttgg caaaaccaat ccaaaggatc tcttgcagtt
    14461 ggcgactacc ttgtctagtg tgccacggat tcgtgcgatt ttagaaggga tggagcaacc
    14521 tactctagcc tatctcatcg cacaactgga tgcaatccct gagttggaga gtttgattag
    14581 cgcagcgatt gctcctgaag ctcctcatgt gattacagat gggggaatta tccggactgg
    14641 atttgatgag actttagaca agtatcgttg cgttctcaga gaagggacta gctggattgc
    14701 tgagattgag gctaaggagc gagaaaactc tggtatcagc acgctcaaga ttgactacaa
    14761 taaaaaggat ggctactatt ttcatgtgac caattcgcaa ctaggaaatg tgccagccca
    14821 ctttttccgc aaggcgacgc tgaaaaactc agaacgcttt ggaaccgaag aattagcccg
    14881 tatcgaggga gatatgcttg aggcgcgtga gaagtcagcc aacctcgaat acgaaatatt
    14941 tatgcgcatt cgtgaagagg tcggcaagta catccagcgt ttacaagctc tagcccaagg
    15001 aattgcgacg gttgatgtct tacagagtct ggcggttgtg gctgaaaccc agcatttgat
    15061 tcgacctgag tttggtgacg attcacaaat tgatatccgg aaagggcgcc atgctgtcgt
    15121 tgaaaaggtt atgggggctc agacctatat tccaaatacg attcagatgg cagaagatac
    15181 cagtattcaa ctggttacag ggccaaacat gagtgggaag tctacctata tgcgtcagtt
    15241 agccatgacg gcggttatgg cccagctggg ttcctatgtt cctgctgaaa gcgcccattt
    15301 accgattttt gatgcgattt ttacccgtat cggagcagca gatgacttgg tttcgggtca
    15361 gtcaaccttt atggtggaga tgatggaggc caataatgcc atttcgcatg cgaccaagaa
    15421 ctctctcatt ctctttgatg aattgggacg tggaactgca acttatgacg ggatggctct
    15481 tgctcagtcc atcatcgaat atatccatga gcacatcgga gctaagaccc tctttgcgac
    15541 ccactaccat gagttgacta gtctggagtc tagtttacaa cacttggtca atgtccacgt
    15601 ggcaactttg gagcaggatg ggcaggtcac cttccttcac aagattgaac cgggaccagc
    15661 tgataaatcc tacggtatcc atgttgccaa gattgctggc ttgccagcag accttttagc
    15721 aagggcggat aagattttga ctcagctaga gaatcaagga acagagagtc ctcctcccat
    15781 gagacaaact agtgctgtca ctgaacagat ttcactcttt gatagggcag aagagcatcc
    15841 tatcctagca gaattagcta aactggatgt gtataatatg acacctatgc aggttatgaa
    15901 tgtcttagta gagttaaaac agaaactata aaaccaagac tcactagtta atctagctgt
    15961 atcaaggaga cttctttgac aattctccac ttttttgcta gaataacatc acacaaacag
    16021 aatgaaaagg agctgacgca ttgtcgctcc cttttgtcta ttttttaagg agaaagtatg
    16081 ctgattcaga aaataaaaac ctacaagtgg caggccctgg cttcgctcct gatgacaggc
    16141 ttgatggttg ctagttcact tctgcaaccg cgttatctgc aggaagtctt aggcgccctc
    16201 cttactggga aatatgaagc tatttatagt atcggggctt ggttgattgg tgtggccgta
    16261 gtcggtctag ttgctggtgg actcaatgtt gtcctcgcag cctatattgc ccaaggagtt
    16321 tcatccgacc ttcgggagga tgccttccgt aaaattcaaa ccttttctta tgctgatatt
    16381 gaacaattta atgcgggaaa tctagtcgtt cgaatgacaa atgatatcaa ccagattcag
    16441 aacgttgtca tgatgacctt ccaaattctt ttcagacttc ccctcttgtt catcggttcg
    16501 tttatcctag cggttcaaac cttaccttct ctgtggtggg tgattgttct catggtagtc
    16561 ttgatttttg gtttgactgc tgtcatgatg ggaatgatgg ggcctcgttt tgccaagttt
    16621 caaacccttc ttgagcgcat caatgccatt gccaaggaaa atttacgtgg cgttcgtgtg
    16681 gtcaagtcct ttgtccaaga aaaagagcaa tttgctaagt ttacagaggt ctcagacgag
    16741 cttcttggtc aaaaccttta cattggttat gccttttcag tagtggaacc ctttatgatg
    16801 ttggttggtt acggggcggt cttcctctct atttggctgg tcgcgggaat ggttcagtcg
    16861 gatccgtctg ttgttggttc catcgcttct tttgttaatt acctaagcca gattatcttt
    16921 accattgtta tggttggatt tttgggaaat tctgtcagcc gtgccatgat ttccatgcgt
    16981 cgtattcgag aaattcttga cgcagagcca gctatgacct tcaaggatat cccagatgaa
    17041 gagttggttg gaagccttag ctttgaaaat gtgaccttta cctatccaat ggacaaggaa
    17101 ccgatgctga aagatgtgag ctttactatt gaacctggtc aaatggttgg tgtagttgga
    17161 gcgactggtg caggaaagtc aaccttggct caattgattc cacgtctctt tgatccacag
    17221 gaaggggcta tcaaaatcgg aggtaaggat attcgagaag tgagtgaagg aaccctgcgt
    17281 aaaacagttt ccatcgttct ccaacgtgcc attcttttta gtggaacgat tgcagataac
    17341 ttgagacagg ggaagggaaa tgctactcta tttgaaatgg agcgcgcagc caatattgcc
    17401 caggctagtg aattcattca tcgtatggag aaaacctttg aaagtccagt tgaagaacgg
    17461 ggaaccaatt tctctggtgg acaaaaacaa aggatgtcga ttgcgcgtgg gattgtcagc
    17521 aatccacgta ttctgatttt tgatgattcg acctcagcct tggatgccaa atcagagcgc
    17581 ttggtgcaag aagctttgaa taaggacttg aaggggacga caaccattat tattgctcaa
    17641 aaaattagct cggttgtcca tgcagacaag atcttggttc taaatcaagg acgattgatt
    17701 ggtcaaggca cgcatgcaga cttggttgcc aacaatgccg tttaccgtga aatctatgaa
    17761 acacagaaat gaaagacaaa ctataagaaa agtcaatagt tttatctaaa ctatttctta
    17821 tttcaatttg atgatttggc gatgatttta gagcacggca aaaagctatt gaaaaagtcc
    17881 attttttcaa aggtaatcct gtgttaattt cagaaattat atcacttttt gttcgtcaaa
    17941 tggcagctct tttttaggat ataaaacagg gttcggataa gtttttttgc aaggtggatg
    18001 atggctacat tgtaatgttt tccttattct aacttagtct taagataggc cttaaaagca
    18061 ggtgaaaagc gagggcatgc tttggcagct tgtatgagta cctaccgcag atgaggggaa
    18121 ccccgtttga ccattcttcc tgctaaatca atctgacctg actgataaat agaagaatcc
    18181 agtccagcga aagcttgtaa ttgagcagga ttatcaaagg catgaatatt tcgaatctcg
    18241 gctaaaatga ccgcccctaa acgattctca atcccagtaa ccgtcgtgat gaccgagttg
    18301 aactcagcca tcaagtcatt gacacatttt ttcgccttgt caatgagcct cttgtaatgt
    18361 ttgatgattt cattacacga gataaaacgt ctatgcgtta tcaaactcat taccaattaa
    18421 aacaaaaagc tgtggttaga tcctttcgga aatcgtcaag cgattggagg aaatgaacta
    18481 atccacagcg gcttattcca agtataccac ttgggctttg gcagtagcta actgcgctaa
    18541 atataatata aggaggagta aaatgaagac agttcaattt ttttggcatt attttaaggt
    18601 ctacaagttc tcatttgtag ttgtcatcct gatgattgtt ctggcgactt ttgcccaagc
    18661 cctctttcca gtcttttctg gacaagcggt gacgcagcta gccaatttag ttcaagctta
    18721 tcaaaatggc aatccagaac ttgtatggca aagcctatca ggaatcatgg tcaatcttgg
    18781 cctgctggtt ttggttctat ttatctctag tgtaatatac atgtgtctca tgacgcacgt
    18841 gattgcagaa tcgaccaacg agatgcgcaa aggcctcttt ggtaagcttg ctcagttgac
    18901 ggtttctttc tttgaccgtc gacaagatgg cgatatcctg tctcatttta ccagtgattt
    18961 ggataatatc ctccaagcct ttaacgaaag cttgattcag gtcatgagca atattgtttt
    19021 atacattggt ctgattcttg tcatgttttc gagaaatgtg acgctggctc tcatcaccat
    19081 tgccagcacc ccattggctt tccttatgct gattttcatc gtgaaaatgg cacgcaaata
    19141 caccaacctc cagcagaaag aggtagggaa gctcaacgcc tatatggatg agagcatctc
    19201 aggccaaaaa gccgtgattg tgcaaggaat tcaagaggat atgatggcag gatttcttga
    19261 acaaaatgag cgcgtgcgca aggcaacctt taaaggaaga atgttctcag gaattctttt
    19321 ccctgtcatg aatgggatgg gcctgattaa tacagccatc gtcatctttg ctggttcggc
    19381 tgtacttttg aatgataagt ctattgaaac aagtacagcc ctaggtttga ttgttatgtt
    19441 tgcacaattt tcacagcagt actaccagcc tattatccaa gttgcagcga gttggggaag
    19501 ccttcagttg gcctttactg gagctgaacg aattcaggaa atgtttgatg cagaggagga
    19561 aatccgacct gaaaaggctc caaccttcac taagttgcaa gaaagtgttg aaatcagtca
    19621 tatcgatttt tcatacttgc ctgataaacc tattttgaaa gatgtcagca tttctgcccc
    19681 taaaggccag atgacagcag ttgttgggcc gacaggttca ggaaaaacga ctattatgaa
    19741 cctcatcaat cgcttttatg atgttgatgc tggtggtatt tattttgatg gtaaagacat
    19801 tcgtggctat gacttagata gtcttagaag caaggtggga attgtattgc aagattcggt
    19861 cttgtttagc ggaacgattc gagacaatat ccgatttggt gtgccagatg ctagtcagga
    19921 aatggttgag gtagcagcaa aagcaaccca cattcacgac tatatcgaaa gtttgcctga
    19981 taagtacgat actcttattg atgatgacca gagcatcttt tcaacagggc agaagcaatt
    20041 gatttcaatc gctcgaaccc tgatgacaga tccagaagtt ctcattctcg atgaagcaac
    20101 ttcaaacgta gatacggtga cagaaagcaa gattcagcat gccatggagg tggttgtagc
    20161 aggtagaact agtttcgtca ttgcccaccg cttgaaaacc attctcaatg cagatcagat
    20221 tattgtcctt aaagatggag aagtcattga acgtggtaac caccatgaac ttttgaagct
    20281 aggtggcttt tattcagaac tctatcacaa tcaatttgtt ttcgaataag aaagaagttg
    20341 tcctatgtgg gcagcttttt cttgtccata aaaaatgttt atcacagcct taaaaaaaac
    20401 atattagacg aaagtcattt tgagtgatat gataggacta tcgttagcat tcgaaaggag
    20461 aggcatcatg gctagaacgg ttgtaggagt tgctgcaaat ctatgtcccg tagacgcaga
    20521 aggcaaaatc attcattcat ctgtatcttg tagattcgca gagatcattc gtcaagtcgg
    20581 tggtctccct ttagtcattc ctgttggtga tgagtcagtt gtacgtgatt atgtggaaat
    20641 gattgacaaa ctcattttga caggaggcca aaatgttcat cctcagtttt atggagagaa
    20701 aaagaccgtc gaaagcgatg attacaatct ggtccgtgac gaatttgaat tggcactctt
    20761 gaaggaagcg cttcgtcaga ataaaccaat tatggcaatc tgtcgcggtg tccaacttgt
    20821 caatgttgcc tttggtggaa ccctcaatca agaaatcgaa ggtcactggc aaggactacc
    20881 tttcgggaca tctcactcta ttgagacagt agaaggaagc gtggtggcta agctatttgg
    20941 gaaagaaagt caggtcaact cagtccatcg tcaaagcatt aaagatttgg cacctaattt
    21001 ccgtgtaact gccattgatt caagagacca aactattgaa gcgattgagt ctatcgacga
    21061 gcaccgcatt atcggtttac agtggcatcc agagtttctg gttaatgaag aagatggcaa
    21121 tttagaatta tttgagtatt tattgaatga actgta
//
LOCUS       DAVLMQ010000030        21135 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000030 DAVLMQ010000000
VERSION     DAVLMQ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21135
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.030"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(41..1378)
                     /locus_tag="VXF95_001384"
     CDS             complement(41..1378)
                     /locus_tag="VXF95_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HEV1081924.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPNINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            complement(1388..1654)
                     /locus_tag="VXF95_001385"
     CDS             complement(1388..1654)
                     /locus_tag="VXF95_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HEV1081925.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            complement(1919..2305)
                     /gene="rplQ"
                     /locus_tag="VXF95_001386"
     CDS             complement(1919..2305)
                     /gene="rplQ"
                     /locus_tag="VXF95_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HEV1081926.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            complement(2317..3252)
                     /locus_tag="VXF95_001387"
     CDS             complement(2317..3252)
                     /locus_tag="VXF95_001387"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HEV1081927.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            complement(3295..3678)
                     /gene="rpsK"
                     /locus_tag="VXF95_001388"
     CDS             complement(3295..3678)
                     /gene="rpsK"
                     /locus_tag="VXF95_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HEV1081928.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            complement(3696..4061)
                     /gene="rpsM"
                     /locus_tag="VXF95_001389"
     CDS             complement(3696..4061)
                     /gene="rpsM"
                     /locus_tag="VXF95_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HEV1081929.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            complement(4079..4195)
                     /gene="rpmJ"
                     /locus_tag="VXF95_001390"
     CDS             complement(4079..4195)
                     /gene="rpmJ"
                     /locus_tag="VXF95_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HEV1081930.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            complement(4220..4438)
                     /gene="infA"
                     /locus_tag="VXF95_001391"
     CDS             complement(4220..4438)
                     /gene="infA"
                     /locus_tag="VXF95_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HEV1081931.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            complement(4555..5193)
                     /locus_tag="VXF95_001392"
     CDS             complement(4555..5193)
                     /locus_tag="VXF95_001392"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HEV1081932.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHCVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            complement(5344..6654)
                     /gene="secY"
                     /locus_tag="VXF95_001393"
     CDS             complement(5344..6654)
                     /gene="secY"
                     /locus_tag="VXF95_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HEV1081933.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            complement(6667..7107)
                     /gene="rplO"
                     /locus_tag="VXF95_001394"
     CDS             complement(6667..7107)
                     /gene="rplO"
                     /locus_tag="VXF95_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HEV1081934.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            complement(7252..7476)
                     /gene="rpmD"
                     /locus_tag="VXF95_001395"
     CDS             complement(7252..7476)
                     /gene="rpmD"
                     /locus_tag="VXF95_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HEV1081935.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            complement(7448..7942)
                     /gene="rpsE"
                     /locus_tag="VXF95_001396"
     CDS             complement(7448..7942)
                     /gene="rpsE"
                     /locus_tag="VXF95_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HEV1081936.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            complement(7960..8316)
                     /gene="rplR"
                     /locus_tag="VXF95_001397"
     CDS             complement(7960..8316)
                     /gene="rplR"
                     /locus_tag="VXF95_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HEV1081937.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            complement(8400..8936)
                     /gene="rplF"
                     /locus_tag="VXF95_001398"
     CDS             complement(8400..8936)
                     /gene="rplF"
                     /locus_tag="VXF95_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HEV1081938.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEITLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            complement(9128..9526)
                     /gene="rpsH"
                     /locus_tag="VXF95_001399"
     CDS             complement(9128..9526)
                     /gene="rpsH"
                     /locus_tag="VXF95_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HEV1081939.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            complement(9811..10080)
                     /gene="rpsN"
                     /locus_tag="VXF95_001400"
     CDS             complement(9811..10080)
                     /gene="rpsN"
                     /locus_tag="VXF95_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HEV1081940.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            complement(10098..10640)
                     /gene="rplE"
                     /locus_tag="VXF95_001401"
     CDS             complement(10098..10640)
                     /gene="rplE"
                     /locus_tag="VXF95_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HEV1081941.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            complement(10664..10969)
                     /gene="rplX"
                     /locus_tag="VXF95_001402"
     CDS             complement(10664..10969)
                     /gene="rplX"
                     /locus_tag="VXF95_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HEV1081942.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            complement(11047..11415)
                     /gene="rplN"
                     /locus_tag="VXF95_001403"
     CDS             complement(11047..11415)
                     /gene="rplN"
                     /locus_tag="VXF95_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HEV1081943.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            complement(11441..11701)
                     /gene="rpsQ"
                     /locus_tag="VXF95_001404"
     CDS             complement(11441..11701)
                     /gene="rpsQ"
                     /locus_tag="VXF95_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HEV1081944.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            complement(11726..11932)
                     /locus_tag="VXF95_001405"
     CDS             complement(11726..11932)
                     /locus_tag="VXF95_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HEV1081945.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            complement(11942..12355)
                     /gene="rplP"
                     /locus_tag="VXF95_001406"
     CDS             complement(11942..12355)
                     /gene="rplP"
                     /locus_tag="VXF95_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HEV1081946.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            complement(12359..13012)
                     /gene="rpsC"
                     /locus_tag="VXF95_001407"
     CDS             complement(12359..13012)
                     /gene="rpsC"
                     /locus_tag="VXF95_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HEV1081947.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            complement(13025..13369)
                     /gene="rplV"
                     /locus_tag="VXF95_001408"
     CDS             complement(13025..13369)
                     /gene="rplV"
                     /locus_tag="VXF95_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HEV1081948.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            complement(13381..13662)
                     /gene="rpsS"
                     /locus_tag="VXF95_001409"
     CDS             complement(13381..13662)
                     /gene="rpsS"
                     /locus_tag="VXF95_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HEV1081949.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            complement(13766..14599)
                     /gene="rplB"
                     /locus_tag="VXF95_001410"
     CDS             complement(13766..14599)
                     /gene="rplB"
                     /locus_tag="VXF95_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HEV1081950.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            complement(14617..14913)
                     /locus_tag="VXF95_001411"
     CDS             complement(14617..14913)
                     /locus_tag="VXF95_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HEV1081951.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            complement(14913..15536)
                     /gene="rplD"
                     /locus_tag="VXF95_001412"
     CDS             complement(14913..15536)
                     /gene="rplD"
                     /locus_tag="VXF95_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HEV1081952.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            complement(15561..16187)
                     /gene="rplC"
                     /locus_tag="VXF95_001413"
     CDS             complement(15561..16187)
                     /gene="rplC"
                     /locus_tag="VXF95_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HEV1081953.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            complement(16403..16711)
                     /gene="rpsJ"
                     /locus_tag="VXF95_001414"
     CDS             complement(16403..16711)
                     /gene="rpsJ"
                     /locus_tag="VXF95_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HEV1081954.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            complement(16977..17594)
                     /locus_tag="VXF95_001415"
     CDS             complement(16977..17594)
                     /locus_tag="VXF95_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HEV1081955.1"
                     /translation="MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAHELESLQRDILALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            complement(17591..18181)
                     /gene="nrdG"
                     /locus_tag="VXF95_001416"
     CDS             complement(17591..18181)
                     /gene="nrdG"
                     /locus_tag="VXF95_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HEV1081956.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVSGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLAQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELPDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            complement(18174..18680)
                     /locus_tag="VXF95_001417"
     CDS             complement(18174..18680)
                     /locus_tag="VXF95_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081957.1"
                     /translation="MELRRPRLADKETVLEMMTEFEKFQSPHDGGFWNTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVVFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            complement(18724..18864)
                     /locus_tag="VXF95_001418"
     CDS             complement(18724..18864)
                     /locus_tag="VXF95_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081958.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            complement(18876..21083)
                     /gene="nrdD"
                     /locus_tag="VXF95_001419"
     CDS             complement(18876..21083)
                     /gene="nrdD"
                     /locus_tag="VXF95_001419"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HEV1081959.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKQEDYAWK
                     KAQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHRLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
BASE COUNT         5803 a         4726 c         3990 g         6616 t
ORIGIN      
        1 catctaatct taaatagaac ttaaaatttc tcctattttc ttaattttta aaactatgaa
       61 ttggtgctgg gatttgtcca ccgcgagaga tgaagtcgac agacgaagcc ccattaacct
      121 tcataacggg tgcagttcct aatagaccac caaactcaat catatcgcct tctcttcctt
      181 tgggaatgat acgaacagct gttgttttca tgttgataac accgattgct gcttcatccg
      241 caatcatagc cgcaatagtt tcagcaggcg tatcttctgg gatggcaatc atatccaatc
      301 caacagaaca gatagccgtc atagcttcta gtttttctaa attaagagag ccattttgca
      361 ctgcagcaat cattccttca tcctcagaaa cagggataaa ggcaccagat agaccaccga
      421 cctggttaca ggccatcact ccaccctttt taacttggtc gttcaagagg gccaaggcag
      481 ctgtcgttcc atgcgtgcca actgtttcta gccccatttc ctcaaggaca cgtgccacag
      541 agtctccaac cgcaggggtt ggtgccaaac tcaagtccac aataccaaac tccacaccca
      601 gtctctcact ggccatttga ccaaccaatt gaccgatacg agtgatttta aaggcagttt
      661 tcttaactgt ttcggctact acatcaaagc tctgtccacg aactttttcc aaagcacgtt
      721 tcacaacacc aggaccagaa actccgacat tgatgataac atctgcttcc ccaacaccat
      781 gaaaggcacc cgccataaat ggattgtcct caacagcatt agcgaataca accaacttgg
      841 ccactcccat atctgaaaga tttgctgttt ccttgataat tcgtcccata tctgccacag
      901 ccgtcatatt aataccagac ttggttgagc cgatattgac tgacgagcag accttatccg
      961 tctcagccaa agcgcgagga atggaattga tgagaatctc atctcccttt tgataacctt
     1021 tttgtactaa ggcagaaaaa ccaccaataa agtccacacc aatctctttc gcagccttat
     1081 caagcgcttt tgccagaacc acgtagtccg tcgcatctgt cgctgcccca atcagagaaa
     1141 taggtgtcac cgatacacgc ttattaacga taggaattcc caactcagcc gcaatttcat
     1201 caccaacagc tactaaatta gccgcctttg tcgtaatttt ttgatagatt ttctccgcag
     1261 cacgattgat atttggatcg atacagtcca aaagagaaat ccccatggta atggttctaa
     1321 tatcgaagtt ttgctcctca atcatggcga tggtttcagt aacttgtcta atatccatga
     1381 tgacctccta gatattatac atagcttcga aaatcgctgc actctgaata ttgattttta
     1441 cattcaaagt ttgcccaaaa gcttcaaatt cattacgaag ataggtaaaa tcttgctttt
     1501 catcactaga tacaacagcc atcatcgtaa aatattcatc caatacagtt tgagagatat
     1561 cgtcaatatt caatcctaat tctgcaattt taccagaaac acctgcaaca attccagatt
     1621 tatctttacc aacaacagtt ataatcgctt tcataagtaa actccaattc ttcttaaaat
     1681 aagaaacctt aacattaaac aggattcttt tcaaatagta tagcataatt ctaacgaaaa
     1741 tactcaaaaa cgcctgctta cgaagttgtt cttaagaaaa aaacaatttc gtaaacaagc
     1801 gtctactatc ccaacttatg atgagtgttc ccgctaggac cgaaatccta gcggtagacc
     1861 agagctagac taagagcaca agactccatc atcataacac tcaacaaaat tgatgatttt
     1921 atactaattc gatgatcgcc attggcgctg catcaccacg acgtggttca gttttaagga
     1981 tacgagtgta tccaccgtta cgttcagcat aacgaggtgc gatttctgag aacaattttt
     2041 gaagtgctgt agtagaagtg tacttatcag ttgcttcatc atagttttca gatgcgattt
     2101 cattacgtac gaaagcagct gcttgacgac gtgcatgcaa atcaccacgt ttacctagag
     2161 taatcatttt ttcaacagtt ttacggattt ctttagcacg agcttcagtt gtcacgattg
     2221 attcgttgat caaaaggtca gttgtcaaat cgcgaagcat tgctttacgt tgtgagctag
     2281 tgcgtcctag tttacggtaa gccatgtatt cctcctttat ttatctttta atccaagacc
     2341 caaatcaatg agtttgagtt tcacttcttc caaactcttg cgtccaagat ttcgtacttt
     2401 catcatctct gcttcagatt tttctgtcaa atcatgcaca gtattgatac cggcacgttt
     2461 taaacagttg tatgaacgca cagacaagtc cagttcctca atcgtacgat ctaaaatacg
     2521 gtcgtcagat tcagtatcag cttctttcat cacttcagtt gacttagcaa tctcagtaag
     2581 atttgtaaac aaatcaagat gttctgtcaa aatacgtgct gaaagcccta aagcatcttc
     2641 tggaataatt gttccatttg tcaagatttc aagggttaat ttgtcgaaac catcattgct
     2701 acctacacga gcaggttcca cttgatagtt gacttttgta actggtgtat aaatagaatc
     2761 tacagcaagt gttccaactg gtgcattatc ctttttattt tcatcagcag gtacatatcc
     2821 acgaccactg ttaacagtca tagtcgcttt tagagaagaa ccttcaccga ttgtaaagag
     2881 ataatgatct ggatttacaa tttcaatatc gctatctgtc aaaatgtcac cagctgttac
     2941 ttcagcagga ccttcaacat ccagttcgat gattttttcg tcttcaacgt acgatttcac
     3001 tgcaattcct ttaatgttca gaatgatttg catcacgtct tcacgaacac ctggaactgt
     3061 gtcaaactca tgtaacacac catcaatgtt gatagatgtc acagctgctc ctggtagaga
     3121 agctagaagt acacgacgaa gagagttacc aagagttgta ccgtagccac gttcaagtgg
     3181 ttcgattaca aacttgccat aatctttatt ttcatcaatt tttgttatat ttggtttttc
     3241 aaactcgatc atttagttac tccctcttaa acgaaaagca gtgtaatgcg atgattatac
     3301 acggcgacgt tttggaggac gagcaccatt gtgtggcact ggagtcacat cacgaattgc
     3361 tgttacttca agaccagcgg cagcaagcgc acgaatagct gactcacgac cagaacctgg
     3421 accttttaca gtaacttcaa ctgatttaag accgtgttct tgtgcagatt tagcagcagc
     3481 ttcagaagcc atttgagcag cgaatggtgt agatttacga gaacctttga aaccaagagc
     3541 accagctgat gaccaagcaa ttgcattacc atgcacatca gtaatcataa caatagtgtt
     3601 attaaatgta gcgtgaatat gagcaatacc agattcgata ttctttttca cacgacgttt
     3661 acgtgttggt ttagccaaga cttttacctc ctatattatt ttttcttacc agcaatcgca
     3721 acagctttac ctttacgagt gcgagcgttg tttttagtat tttgtccacg gacaggaagt
     3781 ccacgacggt gacggatacc acggtatgaa ccgatttcca tcaaacgttt gatgttcaag
     3841 tttacttcac gacgaaggtc accttcaact ttgattgcat ccacttcacg acggatagca
     3901 tcttcttgat ctgatgtaag atcacgtaca cgaacatctt ctgagattcc agcagcagcc
     3961 aaaattttct tagatgttgc aagtccgata ccataaacat aagtcaatga gattactacg
     4021 cgtttgtcat ttggaatatc aactccagca atacgagcca tgttttctcc tttctatctt
     4081 atccttgacg ttgtttgtgt tttggatttg ctgggcaaat taccataaca cgaccattac
     4141 gacgaataac tttacagtat tcgcaaattg gtttgaccga tggtcttact ttcatttctt
     4201 atccctccaa gtttttcgat tatttaaagc ggtaagtgat acgtccacgt gtcaagtcat
     4261 atggactcat ttcgacagta acacgatctc ccgctaaaat acgaatatag tttttacgaa
     4321 ttttaccaga aactgttgct aaaatctgat gtccattttc aagttcaacc gtaaacattg
     4381 cattcggcat tgtatcaact actttgcctt caacttcaat cacatcgtct tttgccacgc
     4441 aaaagcacct ccataaattt cgattcgatg cctctagaca cagagacaac aattataagt
     4501 cagactatct cagtataaca tttgtagcgg atttttgcaa gtgtgaaaaa cgctttattt
     4561 caaatttgtc aatacttttt caatatctga gaagacatca ttgatatctt gattaccttc
     4621 gatgtcatga accaaacctt tggcacggta gtgagcaatg attggttctc cttgagcaat
     4681 attaacatcc aaacgacgtt ttactgtctc aggcttatca tcttcacgtt ggtagtaatc
     4741 ttcttcttta tagtcaactg gtgggttaaa gaccttgtgg aaagtttctc cagttacgca
     4801 gtggatgata cggccactca aacgttccaa gaggctgtca gggttcactt caatattgat
     4861 aataccttct agttcaatgc caagttcagc caatgttttg tccaaggcat gagcttgttc
     4921 aattgtacgt gggtaaccat ccaataagaa tcctgtttct ttaatatcat cttgtgaaag
     4981 gcgttctttt acgattccat ttgtaacttc gtcaggaacc aattcaccct tgtcaatata
     5041 tgacttagca agaacaccca tttcagtttg atttgccatt gcagcgcgga acatatcacc
     5101 tgttgagata tgtgcaacat ggaattgttc tacgattttt gctgcttgag ttcccttacc
     5161 tgcaccaggt aagcccataa tcaaaagatt catgatttga tctccttatt ttatttttaa
     5221 atagaagcaa aaagtctttt cacccctatt taaaaacaaa atagaagagg ggagatccaa
     5281 ctcttacaaa tgtcagagtt taaacctcca ctccctcagt atttactgat tcagtaaata
     5341 cttttattct gttctgtcca tgaaaccaac atacttacgt ttcaataggt aaccttccaa
     5401 ttgcttgatt ccttcgatac ctgtagagat aatgatcaag agacttgttc caccaaaggc
     5461 aacaacatca gaaagaccaa atacatcttt agctgcaatc ggtaaaatgg aaatcacacc
     5521 aaggaagagg gaaccaacag ttgcaagacg acgaagaagt ttagacatat attcttctgt
     5581 acctttacca ggacgaactc catggatata ggcaccactc ttttgtaggc tctctgctgc
     5641 tttttcagga ttaatctgta caaacgtata gaagaatgta aagagaataa tcaacaaagc
     5701 atacatggca ataccagttg gagaagtagt tgccaacatc tcttgtgcta cccttaccca
     5761 agcccaatca tgacctgtgg cactcaaaaa ctgaagaata gccgcaggcg ctgcagtaat
     5821 cgaactggca aagataacag ggataactcc agcaggattt acctttaacg gaaggtaaga
     5881 gctagatgga gcaccttgtg caaccttagt atattggatt ggaattttgt attctgcttg
     5941 ttgaacataa gttgtaaagt aaataatcaa caatacagta ataatcaaaa tgattacgaa
     6001 aatgatagat gaagtgatac ggctacttgg gacgttcaca aagtagtcca catagatgcc
     6061 ctgaatcatc tctggaattg aagaaacaat cccggcaaag ataatcatgg aaacaccgtt
     6121 tccgtatccc ttatctgtaa tttgctcacc caaccaagtg acaatcatac taccagctgt
     6181 taagatgata ccaatcgtca gaaaaacttg tggagttaaa gcagttttaa tcaattgagc
     6241 tccagccaag gtattaaaac cagctgtaat cccgatagat tgcacaaaag cgagaactag
     6301 agcaatataa cgagtagctt gattcaattt tcttcgacct acttcccctt gtttacccca
     6361 ctctacaaac ttgggtaaaa tatccatttg caagagttgg acaacaatag aagcggtgat
     6421 atagggacta actcctaagg caaaaatcga aaagtttttt agggcattcc ccgacaccaa
     6481 gctcaacatg tttaagaagg ataatccact taaagcattc aagctattgg cattcacacc
     6541 aggaactgta atgctagttc cgatacgaaa gaccaaaacg ataaaaattg taaataaaat
     6601 ttttgatcga acctgcttga ctttaagagc ttctcttaat aatttaaaaa acataggtca
     6661 cctctcttag atgacttcta ctgaaccacc tttagcagtg atagcttctt cagctgattt
     6721 agagaattta gctgctttca cagtcaattt cttagtcaac tcaccgttac caagaatttt
     6781 aatacctgac ttttcagctt taacaattcc tgcttcgata agaacaactg gagttacttc
     6841 agcaccatct tcaaagacgt tcaattggtc aaggttcaca attgcgtatt ctttagcgtt
     6901 gatgttagtg aatccacgtt ttggaagacg acggaacaat ggagtttgtc caccttcaaa
     6961 accaaggcga actccgccac cgctacgagc tttttgacct ttttgaccac gaccagatgt
     7021 tttaccgtta cctgatgaag taccacgacc aacgcggtta cgtactttac gagaaccttc
     7081 tgcaggtttc aattcatgaa gtttcatttt tattttctcc tcttttgtaa aatgctagcg
     7141 ccgataaggg agaaaaggtt gtctccccca tcaactcgcc tatacgatgt catcatagat
     7201 gactatatct agttttaggg gatggtacag tgcacatccc ctaaaacttc attagtttac
     7261 ttcttcaact gttactaagt gagatactgc tgtgatcata ccacggatag cagcgttatc
     7321 ttctttaata acagagctgt tcaatttgcc aagtccaagt gctacaacag ttttacgttg
     7381 tgatggaatg cgtccgattg gagacttagt caaagtaatt ttaatttgag ccattttatc
     7441 ccctttctta tgccaaatca gaaactgaaa taccacgaag ggcagcaatt tcttcagcgc
     7501 gtttcaattg tttcaaacct tcaacagttg cacgaacaat gttgattgga gtgttagaac
     7561 caagtgattt agatgtaata tctgccacac ctgccaattc cacaacggca cgaactgcac
     7621 caccagcggc aactccagaa ccttctacag caggtttcaa caatacttta gctccaccga
     7681 attctgaaag aacttcgtgt gggattgttg ttccaaccat aggaacttcg atcaagtttt
     7741 tcttagcatc atctactgct ttacggattg cttctggaac ttcttgagct ttaccagtac
     7801 caaatcctac gcgaccattg tggtcaccaa caacaacaag agctgcgaaa cgaagacgac
     7861 gtccaccttt aacaactttt gtaacacggt tgacagcaac tacgcgttct tctaattcaa
     7921 ctgcattgtc tttaaatgcc attttctagt gtcctcctat tagaatttca atccgttttc
     7981 acgagctgca tcagccaaag ctttcacacg tccgtgatat agatatccac cgcggtcgaa
     8041 caccacttct gaaatacctt tagcgtttgc acgttctgca acgagtttac cgacagcaac
     8101 ggcttgttca gttttagttc cttttgaaac ttctttatca agagttgaag cacttgcgag
     8161 cgttacaccc gctacgtcat caatcacttg agcgtagatg cctgtattag aacggaatac
     8221 gttcaaacgt gggcgatcag cagttccaga gagttttccg cgaacgcgac ggtggcgttt
     8281 ttggcggagt ttgtttttat ctggttttga aatcacagtt ttcacctctt tagttttaaa
     8341 tcgtgtgcta tgcacaaagt tggaaaatag gttggtggtt gatgatcaac cactcaacat
     8401 tatttacctg ttttaccttc tttacggcga acgaattcac caacgtaacg gataccttta
     8461 cctttatatg gttctggtga acgaaggcta cgtacgtaag cagctgtttg accaactact
     8521 tcttttgaaa ttccgctaac aacgattgtt gttgggtttg gaagttcaaa agtaattcct
     8581 tctggagctt caacttcgtc tggatgagat ttaccaacag ccaaaacaag tttagatcct
     8641 tgaagctgtg cacggtaacc aaccccacgc atttcaagtt ctttcttgaa tccttctgat
     8701 acaccaacaa ccatgttgtt caaaagggca cgagtagttc cgtggatagt tttcatttct
     8761 tttgaatcgt ttggacggtg aagagttatt tcagtacctt ccacacggat ttcaatatct
     8821 tttgagaact cacgagtaag ttctccttta ggtcctttta cagttacaac gttgtcattg
     8881 ttagcgagtt caacaccagc aggcaacacg ataactttat taccaatacg tgacatgttt
     8941 attttctcct gttaaattgt caggccagaa cggccagttt tcacggggtt cagatactta
     9001 tttagttcaa gagctgaact gaacacgctc taagaactgt gcaaaataga taagttggct
     9061 tgtttgtaaa caaacttctc caacttccta attttgcttt gttctttacg agctttgtat
     9121 cttgatttta ccaaacgtaa gcgataacct caccaccaac attcttttgg cgtgcttctt
     9181 tatcagtaag caaaccttca gaagttgaaa ggatggcaat tccaagtccg ttaagaactt
     9241 ttggaaggtc ttcacgtttt ttgtagacac gaagtcctgg tttagaaaca cgtttcaagt
     9301 tagtgataac tttctcacca tttggtccgt atttaagaaa tacacggatg acgccttgtt
     9361 tgtcatcttc aatgatttca acgtttttta caaaaccttc gcgtttaagg atttcagcaa
     9421 tccctttttt gatgtttgat gcaggtactt caagtacttc gtgtttagct tggttagcat
     9481 tacgaatacg agttaggaag tctgcgattg ggtcagtcat aaccattttg tttttctcct
     9541 cttactagta gtttgcaagt tgcacttgct agttaataca tgatacaaag agcgtaacag
     9601 tacgagcaaa aatagacaat ttaatgcaga agcaatgctc caaagcaaat tggtcttttt
     9661 tgccaaagct gtagctcgtg ttcaaattgg caagcccaat tgaacccggg ctaaactctg
     9721 tgtgaaaaag ataaactttc ctagaaactt tagtttcttc gtcaagtttc ctatttttac
     9781 ttggagtttt gacgctcttg atatcttaaa ttaccaagat gcttttgtta caccaggaat
     9841 ttgaccttta tgcgcaagtt cgcgaaaagc gatacgactc agaccaaatt tgcggtaaac
     9901 tgaatgtggg cgccccgtaa ctctacaacg attatgtaaa cgagtcggtg aggcgttgcg
     9961 aggtaattta gataaacctt cgtagtcccc tgccgccttt aatgcagcac gtttttcagc
    10021 ataacggtca acaatttttt ggcgtttagc ctctctagct accattgatt ttttagccat
    10081 tagatttacc tcctatatta ttttgcaaaa ggcattccaa ggcctgtaag caatgcacgt
    10141 gactcttcgt cagtgttagc agttgttacg ataacgatgt caagaccacg agttttgtca
    10201 acgtcatcga agttgatttc tgggaagatt aattgttctt tcacaccaag tgtgtagttc
    10261 ccgcgtccat caaatgattt tgttggaaca ccgtggaagt cacgtacacg tggaagtgaa
    10321 actgatacca atttatccaa gaattcgtac atacgttcac cacgaagggt aacttttgca
    10381 ccgatcgcaa caccttcacg aagacggaag ccggcgattg attttttagc tttagtgata
    10441 agtggttttt gacctgagat aagtgccaat tcttcagcag ctttttcaag gcttttagcg
    10501 tttgatacag cttcaccaac acccatgttc aaaacaatct tatctacttt aggcacagcc
    10561 atcactgatg agtagttgaa ttgttctgtc aaagcaggaa ctacttcatt aagatatttt
    10621 tcttttaaac gatttgccat tatacttctc ctttccttcg tgattaatca agcacttcgc
    10681 ctgatttttt gttgtagcga acttttttac cgtctacaaa tttgtaacca acacgaccag
    10741 ctacaccatt tttgtccaaa acttgaacat ttgatacgtg gatagctgct tctttctcga
    10801 tgataccacc ttgaggaagc tcgttagttg gacgttggtg tttcttaaca atgttaacac
    10861 cttcaacgat aactttgttt acttttggaa gggcagtaag gacaacagct tctgttccct
    10921 tatctttacc agcgattacg cgaactttgt cgcctttttt tacaaacatt aggtttctcc
    10981 ttgatttttc ttacgcccat aagggcaccc tagcttgaag ctaggggact agtttgttcc
    11041 taaaaattaa agtacttctg gagcaagtga cacgatcttc atgaagccac cttcacgcaa
    11101 ttcacgtgca actgggccaa agatacgtgt tccgcgagga gttttgtctt cacggatgat
    11161 aactgctgcg ttttcgtcaa atttgatgta tgaaccatca gcacgacgag cacctgattt
    11221 agtacgaacg ataactgctt taacaacgtc acctttttta accgcaccac caggagtagc
    11281 ttgttttaca gatgccacga taacatcacc gatgtttgca aatttacgtc ctgaaccacc
    11341 aagaactttg atagtcaaga tttcgcgagc accgctgttg tctgcgactt tcaaacgagt
    11401 ttctgtttga atcatttcag ttttctcctt tcaggtttga ttagatgatg accgcttctt
    11461 caacaacttc tacaagacgg aaacgttttg tagctgaaag cgggcgagtt tccatgatac
    11521 gtacgatatc gccttctttg gcaacattgt tttcatcatg agctttgtat tttttagagt
    11581 agttaatacg tttaccatag actgggtggt tacgttttgt ttcaactaca actgtgattg
    11641 tcttgtccat tttgtcagat acaacacgtc caacaagaac tttacgatta ttgcgttcca
    11701 ttgaaatttc tccttcccta gtctattatt tcgcttcaga ttgaactgtt ttgatacgag
    11761 cgatttgttt tttaacttct ttcaagcgag ctgtttgttc caattgacca gtagcagctt
    11821 ggaaacgaag ttcaaacaat tcttttttca attcgttttc gcgcttcgcg agttcttctt
    11881 gagaaagacc acgaagttct ttaacaaatt cttttacttc attaagtttc atgccttctc
    11941 cttattctgc ttcacgtttt acgaatttac atttaactgg caatttgtgg ctagcaagtc
    12001 gaagcgcttc acgtgcaatc tcttcagata caccagcgat ttcgaacatc actttaccac
    12061 gtttaactgg tgctacccaa ccttcaggtg cccctttacc agatcccata cgcacaccga
    12121 tagctttagc agtgtatgat ttgtgtggga agattttaat ccaaacttta ccaccacgtt
    12181 tcatgtaacg agtcatggcg atacgagcag cttcgatttg gcggttagtg atccagtggc
    12241 tagttgtagc ttgaagaccg tattcaccga atgctacttc ttttccacct tttgcttcac
    12301 cgcgcatttt tccacggaac tcacgacggt gtttaacacg tttaggtact aacattggtt
    12361 atttacctcc tttagtgttt ttacgagctg gaagaacttc accacggtag atccatactt
    12421 taacaccaag tttaccgtat gtagtatctg cttcttccca agcgtaatcg atatctgcac
    12481 gaagtgtgtg aagcggaaca gttccttcag agtatccttc agcacgggcg atatctgcac
    12541 cgttcaaacg acctgatact tgagttttga ttcctttagc tccagcacgc attgcacgtt
    12601 ggattgcttg tttttgtgca cgacggaaag caacacgttg ctccaattga cgagcaattc
    12661 cttcacctac aaggtgagca tccaaatcag gttgtttgat ttcgatgatg ttgatgtgta
    12721 cttgttttcc agtcaatttg ttaagttttg cacggagtgc atcaacgtta gcaccacctt
    12781 taccgataac catacctggt ttagcagtgt gaagtgaaac gttaactttg tttactgcgc
    12841 gttcgatttc aatagttgaa actgctgcgt cagcaagttc tttttgaacg aatttacgga
    12901 ttgcaagatc ttcatgaagg taatccgcgt attctttttc agcataccat ttggcatccc
    12961 aatcacggat gatgccgaca cgcataccaa ttggatgtac tttttgaccc acgattttac
    13021 ctccttattt ttctgcaaca gctacagtga tgtgagctgt acgtttgttg attggtgaag
    13081 ctgaaccttt cgcacgtgga cggaaacgtt tcatagttgg tccttcgttt gcgaatgctt
    13141 cagatactac caagttagct ttatccaaac caaagttgtt ttcagcgtta gctacagctg
    13201 agttcaaaac tttcaagatg atttcagcag ctttgtttgg agtgaatgtc aagattgcga
    13261 ttgcatcggc tacgctttta ccacggatgt tatcaagaac aagacgtgat ttacgaggtg
    13321 aaacacgtac tgtacgagcc attgctttag ctgaagtaat ttctgccatt tatgttctcc
    13381 ttattttcta cgtgttttct tgtcgtctgc agcgtgacct ttgtaagtac gagttggtgc
    13441 aaattcacca agtttgtggc ctaccatgtc ttcttggatg taaacaggta cgtgtttacg
    13501 tccgtcataa actgcaatag tgtaaccaat gaaacttggg aagatcgttg aacgacgtga
    13561 ccaagtttta ataacttttt tcttttcgtc gttagcttga gcttcaactt ttttcatcaa
    13621 atgctcatcg acgaaaggtc cttttttaag actgcgtccc atttttatat tttctccttt
    13681 aaatgttgta ccacagcggc ttgcactcct atggagcgct accgagctgg cggatttact
    13741 agttgcttaa gcgactagtt taatattatt tctcgttgcg acgacgaacg ataagtttgt
    13801 cagatttcgc tttcttgtta cgagttttaa gaccaagagc aggtttgccc catggagtag
    13861 atggtgcttt acgaccaact ggtgctttac cttcaccacc accgtgtggg tgatcgttag
    13921 ggttcattac agaaccacga actgttgggc ggataccttt ccaacggcta cgtcctgctt
    13981 taccaaggtt tacaagtcca tgttgttcgt ttccgacaac accaactgta gcacggcaag
    14041 ttccaagaat catacgaact tcacctgatt gaagacgaac aagaacgtat ttaccttcag
    14101 aacccaatac ttgagcagat gcaccagcag cacgtaccaa ttcaccacca cgacctggtt
    14161 tcaactcgat gttgtgaatc aaagtaccaa ctgggatgtt agcaagtgga agagcgtttc
    14221 cgactttgat atctgcttct ggacctgaaa cgatacgttg acctacttca agaccttttg
    14281 gagcgatgat gtatgctttc acaccatcag tgtagtgtac aagagcgatg tttgcagaac
    14341 ggtttggatc gtactcgatt gttttaacaa ctgcttcaac gttgtcttta ttacgtttga
    14401 agtcaaccaa acggtagaaa cgtttgtgtc caccaccttg gtgacgaact gtgatacgac
    14461 cgttgttgtt acgaccagcc ttgctcttca atgcaacaag caatgatttt tcaggagtgc
    14521 ttgttgtgat ttcagcgaaa tccaaagaag tcatattacg gcgaccgttt gttgttggtt
    14581 tataaacacg aattcccacg atatttcctc cttagattat tcagcttcag cagcaaacaa
    14641 ctcgattgct ttagaatcag ctgtaagtgt gatgatagct tttttagttt tgttagtaaa
    14701 accagtgtaa cgtccaacac gtttagcttt tggttttacg ttgattgtgt taacattggc
    14761 aactttaaca ccttcgaaag cagcttcaac agcttgcttg atcaaaagtt tgtgtgcacg
    14821 agtgtcaact tcaaatacat atttccctgc ttcaagttga gccattgagc tttcagtgat
    14881 gacaggtttt ttgataacat catacaaatt cattatgcaa gaacctcctc gattttagag
    14941 atagctgctt gtgtgacaag aagtttgtcg ctatttgcga tgtcaagaac acttgcagtt
    15001 gtagcagttg caactttcac gtttggaagg ttacgagctg aaagagctgc gaattcattt
    15061 ccttcttcaa ggataacaag aactttagaa tcgatgctca atgctgcaag aacttttgca
    15121 aattcagcag tttttggagc tgtaaatgaa agagcgtcta cagctacgaa tttgttttca
    15181 gcaacttttt cagagtaaac tgatttaaga gctaggcgac gaactttttg tggaagtttg
    15241 tagccgtatg aacgtggagt tggtccgaag acaacaccac caccacgcca ttgtggtgag
    15301 cggatagaac cttgacgagc acgtccagtt cctttttgac gccatggttt gcgtccacca
    15361 cctgatactg cagagcggtt tttaacagcg tgtgttcctt gacgaaggct tgcgcgttgg
    15421 ctgatgatta catcaaacac aactgattca tttggttcga taccaaatac tgcatcgcta
    15481 agaacaactt ggccagcttc tttaccagtt tggtcaaata atgttacgtt tgccattgtg
    15541 actgatttcc cctttcttta ttatttacca gctttaactg ctgatttgat agtgataaga
    15601 gatttcttag cacctggtac gttacctttg ataaggataa cgttcttttc tggaacaact
    15661 tgtacaactt caaggttttg aattgttacg cggtcgccac ccatacgtcc tgcaaggttt
    15721 ttacctttga atacgcggtt aggtgcaaca ggtcccatag aacctggacg acggtggtaa
    15781 cgagaaccgt gagccattgg tccacgtgat tgtccgtggc gtttgataac accttggaaa
    15841 cctttacctt tagaagtacc agttacgtca acaacgtccc cagctgcgaa tgtttcaact
    15901 gtaatttcag caccaacttc caagccttca acgtttttga attcacgaat gaagcgctta
    15961 ggagccgtgt tagctttcgc tacatgtcct ttagcaggtt tgttgctcaa tacttcgcgt
    16021 ttgtcatcga aaccaacttg gatagcgttg tatccgtctg tttcaacagt tttaacttga
    16081 agaacaacgt ttggagttgc ttcaataact gttacaggga tcaattcgcc agcttcagtg
    16141 aagatttgag tcattcccac ttttttccct aagattcctt ttgtcatgag aaaatagttc
    16201 cttttctata tttttattca aaaagttttt aacgagcgtt ttttatgctc aagtctaaga
    16261 tacaaagggc gtcaaactca acgtgaaaat aggaaactga cacagtgtct agcagacgcg
    16321 aggaagttta tctttttcac accaagttta gcccgtgttc aattagattg aaacaccagc
    16381 ctctgctctc ttatatttta gattaaagtt tgatttctac gtttacacca cttggaagat
    16441 ccaatttcat caaggcatca actgtttttt gagttgggtt aacgatatcg atcaaacgtt
    16501 tgtgtgtacg catttcaaat tgttcgcgag agtctttgta tttgtgagtc gcacgaatga
    16561 ttgtgtagag gctacgttca gttggaagtg ggattggacc cgcaacttgt gcacctgtac
    16621 gagtagctga ttctacgatt tttgcagccg ctgtgtcaag cgtacggtgt tcgtaagctt
    16681 tcaaacggat acggattttt ttgtttgcca tctttttctc cttttcgtct atttaagata
    16741 ataggctagc tccacaagaa aaccgacgcg gtgttgcgtg gcaatgcaac cgagcgtgtc
    16801 gcaacctctt gcatcaaaac taaggctgta atttacagca ccataataga ataacacaaa
    16861 tcccctgcga ttgcaaggga tttgttaggt tttttcgttt ttttgggatg aaactgtttt
    16921 cctacttttt ctttctaaaa ttagggattt tcttctatat ttcttctata cataagttaa
    16981 gtcctcttga catcaaattt atcttctgat tggtccacta agatatccgc cttagactca
    17041 gtttctttat agtatcgcag atactgctcc cgtctcatct gatggctagc caatataaag
    17101 gatgcatcgc gatttctcac agtcgtatct ctagcaaggc gtcgctttaa ttcggtctcc
    17161 tcatccgtgt agaaacagat ggttttttca aagagttcct tgggtagaaa gccaacagac
    17221 atcccttcga caatcaaaat tggtttggct ccagacaaga cctcactagc cttccaaggt
    17281 tcttcaattg tcaagacatc catacccgcc tgcaaggcaa ggatatctct ctgcaaactc
    17341 tccagttcat gcgccactgg cagactggct gtcacctttt gattcggcgc gtccttgggt
    17401 actaccaaat agcgtccgga ggtgatatag ggatctgttt ctagcaaatt tactgtagta
    17461 gaatctaaag cttggtacaa ttcctgtgca aaggttgatt tacctgaagc tccatgaccg
    17521 tatattccca gtgtcctgac tttccccgtc tcgatctctg agactagttg gtctactaag
    17581 tcttttttct tcattctctc ttcacctgtt catagctttc ttttccgtca ttgagcttgt
    17641 cccaaatcac tacttgccca cttttgagcg atttttgcac atcgataatt cgttggttgg
    17701 acgaacctcg aaactggagc atgagatttc tcttagttcg atcgtatcgt ccatcgacaa
    17761 gaatgtcaat caatgataag agttccagtt tatctggagt ttccaacatc atttcttccc
    17821 aagtgtagcc cgtccaggac caaatgtcct tgtctggcaa ttcctttcgg atgcgtttaa
    17881 ctagaggcaa gagaatgcca gtattgagaa aaggctcccc tcccagcaaa gtcaagcctt
    17941 gaacataggg ttgggcaagg tctgccataa tctgctcttc taattctgct gtatagggaa
    18001 tgccagcatt aaaagaccaa gtcgcaacat tataacatcc ctcgcagtga aacatacagc
    18061 ctgatacata gagagagttg cgcacgcctt cgccgtccac aaagttaaag gccttgtagt
    18121 caatgatacg accttgacta agttcctcgc ttttccattc ttgtggtttt ggattattca
    18181 ttcgctacct ctatccaata acgctcgact ccattgcgag catcctcaaa tattccacca
    18241 tttgctagaa tgactgctct gctagcagga ttattcacgc tacaggtcac cagagctttc
    18301 ttgatgttct tttccttagc aacttgcaag ccctgacgga gagtctcttt tgcataaccc
    18361 ttgcctcttt cagatggacg aatggagtag ccaatgtggc caccttcttc tagtagaaag
    18421 ttactgaggc gcaaccggag attaagaaat ccaactgctt gacctttctc agaaaaaacc
    18481 actaactgaa ttgcaggaac ccatccttca ggcagattaa tccccatttc ctgttcctga
    18541 ttgctttcta accagtcttc atacacaaag ttctctgtat tccagaaacc gccgtcgtga
    18601 ggcgactgaa atttttcaaa ctctgtcatc atctctaaaa ctgtttcttt atctgctaat
    18661 cttggtctgc gtaattccat ccctacctcc cactatgaga aaagcgagag ctggctctca
    18721 cttttatttt ttcttgttct tgtttaaaaa ttgttctctg aagctaagca agcgttcttt
    18781 cttaccagct ccacctttag agtgtttctc gtgataacgg gtcacttgtg cgcgcccctt
    18841 atcgtctagt tgatattttc ccatttcatt tctttctaat ttgttacttg atgcccagct
    18901 attttaatcg ttgaaccatt catatgtttg acacgcgcag cgatttcctt gtgacgcccg
    18961 ttaaccattg gtctcgcttg aggattgcca agatagccac aagtccgttt aacaacgtct
    19021 actgttttag gatcgctatt gccacagttt ggacaagcaa accctctctc agttggttca
    19081 aaatcccctt caaagtcaca cttgtagcaa cggtcaatcg gagtattggt gcctagatag
    19141 cctacacggt cataagcata atcccagaca gcttccaagg cctttggatt ttgctgaagg
    19201 actggatact cacaataatg gatgaaacca cctgacgcac ctgcttctgg atagactttc
    19261 tcaaagtcca atttttcaaa cggtgttgga tttttacgaa catcgtagtg gaaagagttg
    19321 gtgtagtatt ccttgtctgt gatatcagga atagagccaa acttgtctat atctagtcgg
    19381 cagaaacggt ctgtcagact ttcggatggt gttgagtaga tagagaaatg gtagccatat
    19441 tggtctgacc actcttctac acggcgtttc atatcgtgaa tgatgtctag cgtgaattcc
    19501 ttagcatctg gattactttc ccagctgtta ccaaagaaaa ctgtcgctac ttcatacaag
    19561 ccgatatagc ccagcgaaac ggtcgcacga cgattcttaa agagctggtc aacactttct
    19621 tctttaccta gacgatggcc aaaagcaccg tactgataaa gaataggagc attcgctggt
    19681 gtcgcctctt tagtgcgttc gacacggtaa acaagagcat cttctgcgat attcattcgc
    19741 tcgttgaaga tttcccagaa cttattcata tcaccttcag actcaagagc aatacgaggc
    19801 agattaaccg tcacaacacc cagattcatg cgacctgaat tgacttctac accattttca
    19861 tccttccacc cttgaaggaa agaacggcag cccataggca ccttgaaaga acctgtcaaa
    19921 tcaacaatct tatcataaga caagacgtct ggatacatcc gcttggttgc acactctaga
    19981 gccaactgct tgatgtcata gttgggagtt ccttcctcta agttgaggcc tcttttaagc
    20041 gtaaagataa gtttaggaaa gatagccgta cggtgttctg aaccaagacc cttgatgcga
    20101 atgtttaaaa tagctttttg aatttctcgt tcaaaacgac tggttcccag accaaaacct
    20161 aacgaagtaa aaggtgtttg tccatttgaa gtgaagagag tattgatttc atactcaaga
    20221 gattgcatgg catcgtagat gtccttttgc gctttcttcc aagcgtaatc ttcctgtttt
    20281 tcaggcaata cccactcttc tgcatctttg agatgttttt gataattctt ctctgcataa
    20341 ggcgccaaaa tttcatcgat acggtcagct gaacagccac cgtactggct agaagcaacg
    20401 ttggcaatga tttgagaaat ctgtgctgtc gcagtctgga tagacttggg actctctacc
    20461 tctgcatttc caatcttaaa accattttcc aacataccct taaaatcaat caaacagcag
    20521 ttggtcatag gggtataggg actgtagtcc aaatcgtgat agtggatatc ccccttttgg
    20581 tgggcattgg ctacgtgctt aggaagcatt tgcagtccga ttgatttccc aacaatccct
    20641 gctgtcaaat cacgctgagt gttaaagaca tcactgtctt tattagcgtt ttcattgaca
    20701 actgtctggt ctttgttgag aagtttatga atactaaagt tgatatccgt cgcttttgag
    20761 cgctcaaaat ccctctgtgt ccgataagta atatactcct cagccagcgc atattctttg
    20821 gcttcaagga gttcatgttc tacgatattt tgaatttcgt aaatcttaat tccctgtgga
    20881 aagcgactat gaatttctgt aataattcgc tcagtcagat cattgaggcg tttttcaacc
    20941 aggggtgtca catccataac cttgtcagcc gccttgtgga gagccttgtc aatcttgtcc
    21001 acatcaaata caacacgtct cccatctcgt ttctcgacga agagagttgg caaaattgta
    21061 attttttctt ctagtgcaat catatgcatg ctcttttcta aaatgttctt tctaaaaagt
    21121 attataccac tctaa
//
LOCUS       DAVLMQ010000031        20914 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000031 DAVLMQ010000000
VERSION     DAVLMQ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.031"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(106..255)
                     /locus_tag="VXF95_001420"
                     /pseudo
     CDS             complement(106..255)
                     /locus_tag="VXF95_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007895229.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            complement(409..2040)
                     /gene="rlmD"
                     /locus_tag="VXF95_001421"
     CDS             complement(409..2040)
                     /gene="rlmD"
                     /locus_tag="VXF95_001421"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1081960.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKNS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHNLMPLEDFF
                     IQDPVIDQVVVALRDLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSEQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVIIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMNLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(2114..3088)
                     /locus_tag="VXF95_001422"
     CDS             complement(2114..3088)
                     /locus_tag="VXF95_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HEV1081961.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGVEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(3162..3776)
                     /gene="pmp23"
                     /locus_tag="VXF95_001423"
     CDS             complement(3162..3776)
                     /gene="pmp23"
                     /locus_tag="VXF95_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HEV1081962.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     QDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(3776..4750)
                     /locus_tag="VXF95_001424"
     CDS             complement(3776..4750)
                     /locus_tag="VXF95_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HEV1081963.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSSKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDVSRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(4758..6014)
                     /locus_tag="VXF95_001425"
     CDS             complement(4758..6014)
                     /locus_tag="VXF95_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HEV1081964.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYISLIEPGDTVMGMDLASGGHLTHGAPVSFPGQTYNFVSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEELAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(6076..6507)
                     /locus_tag="VXF95_001426"
     CDS             complement(6076..6507)
                     /locus_tag="VXF95_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081965.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(6509..7108)
                     /locus_tag="VXF95_001427"
     CDS             complement(6509..7108)
                     /locus_tag="VXF95_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HEV1081966.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVASLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFDQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(7095..7934)
                     /gene="prmC"
                     /locus_tag="VXF95_001428"
     CDS             complement(7095..7934)
                     /gene="prmC"
                     /locus_tag="VXF95_001428"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HEV1081967.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALDLASENAKNQNLQ
                     IFFKKSDCFTEISEKYDIIVSNPPYISREDESEVGLNVLYSEPHLALFADEDGLAIYR
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKKVRTFKDQFGQDRMVVVDD
                     GQD"
     gene            complement(7934..9013)
                     /gene="prfA"
                     /locus_tag="VXF95_001429"
     CDS             complement(7934..9013)
                     /gene="prfA"
                     /locus_tag="VXF95_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HEV1081968.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASTR
                     DTVTAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(9030..9503)
                     /locus_tag="VXF95_001430"
     CDS             complement(9030..9503)
                     /locus_tag="VXF95_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081969.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKKYQKQFIATNAISLAEAYVYTK
                     NGDFVAPLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDKNFQNQGYFKPIMDK
                     VLDYVRTASAGLGNKLWLSYEPENEHARSCYLSYGFKETGEIYENEVVAIYDFNN"
     gene            complement(9493..10092)
                     /locus_tag="VXF95_001431"
     CDS             complement(9493..10092)
                     /locus_tag="VXF95_001431"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HEV1081970.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGFIRDLPETPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFAPMITSNKEQNYDN"
     gene            10216..10398
                     /locus_tag="VXF95_001432"
     CDS             10216..10398
                     /locus_tag="VXF95_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HEV1081971.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            10536..11909
                     /gene="mnmE"
                     /locus_tag="VXF95_001433"
     CDS             10536..11909
                     /gene="mnmE"
                     /locus_tag="VXF95_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HEV1081972.1"
                     /translation="MITREFDTIVAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIVDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPEAIETSELPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNEGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(11956..12891)
                     /gene="dapA"
                     /locus_tag="VXF95_001434"
     CDS             complement(11956..12891)
                     /gene="dapA"
                     /locus_tag="VXF95_001434"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HEV1081973.1"
                     /translation="MSYQDLKKCKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLVYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFIAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAVLNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(12947..14023)
                     /locus_tag="VXF95_001435"
     CDS             complement(12947..14023)
                     /locus_tag="VXF95_001435"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HEV1081974.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGGSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIASF
                     PGAVLEDDVVHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(14609..14681)
                     /locus_tag="VXF95_001436"
     tRNA            complement(14609..14681)
                     /locus_tag="VXF95_001436"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14646..14648),aa:Thr,seq:ggt)
     gene            complement(14781..15290)
                     /locus_tag="VXF95_001437"
     CDS             complement(14781..15290)
                     /locus_tag="VXF95_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HEV1081975.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(15288..15384)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            15413..15844
                     /locus_tag="VXF95_001438"
     CDS             15413..15844
                     /locus_tag="VXF95_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HEV1081976.1"
                     /translation="MKKPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKVYIFRK"
     gene            15926..16303
                     /gene="mscL"
                     /locus_tag="VXF95_001439"
     CDS             15926..16303
                     /gene="mscL"
                     /locus_tag="VXF95_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HEV1081977.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(16345..17439)
                     /gene="hemH"
                     /locus_tag="VXF95_001440"
     CDS             complement(16345..17439)
                     /gene="hemH"
                     /locus_tag="VXF95_001440"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HEV1081978.1"
                     /translation="MKKAILMMTFGSPEEITFEGVADFFTNIRRGVRPQDHEIQTLYD
                     NYVRIGGTPLQKITRQEVALVEARLGNEYSVYFANKFSSPFIPDVIGQMEADGIEQCI
                     CLILEPHYSFYSVMGYEKFLESKQIQFLVIKDWYQEEALLNYWADEIAKILKEEVKQD
                     SFKVIFSAHSVPIFALDFGDPYIDQIFENSKLVAEKLGLSSEQYTNTWQSESDIGIPW
                     IKPDVLEYLREQTEHPDHYIFVPISFISEHIEVLFDNDVECYDLCQEFGVNYHRPPMP
                     NTDSRLIDALVNTIRVNENQEFKEFLPEEETFDELVPSDETKNILAESEDLQMPEFVK
                     KLIEKKGRENVKMPYLIKKMLEKAGKLPKE"
     gene            17594..18817
                     /gene="pepT"
                     /locus_tag="VXF95_001441"
     CDS             17594..18817
                     /gene="pepT"
                     /locus_tag="VXF95_001441"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HEV1081979.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTSLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLIDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNEELGSNRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(18853..19482)
                     /locus_tag="VXF95_001442"
     CDS             complement(18853..19482)
                     /locus_tag="VXF95_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081980.1"
                     /translation="MNKANQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIETASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            19447..19668
                     /locus_tag="VXF95_001443"
     CDS             19447..19668
                     /locus_tag="VXF95_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1081981.1"
                     /translation="MDLFQELICLVQKTFYFFLSICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNIL"
     gene            complement(19745..20286)
                     /locus_tag="VXF95_001444"
                     /pseudo
     CDS             complement(19745..20286)
                     /locus_tag="VXF95_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521835.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(20390..20914)
                     /locus_tag="VXF95_001445"
                     /pseudo
     CDS             complement(20390..20914)
                     /locus_tag="VXF95_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
BASE COUNT         6056 a         4393 c         3904 g         6561 t
ORIGIN      
        1 agcacaccaa ctatttattt tttgagtttt aaactttggt agaagtcttg aactccttat
       61 atttacataa ctatttgcct ctataactat tatgacacga aaccaacaag caagttcaag
      121 cacctcctta tctttattca aatgaggact aagatattca caaactttat cataaacctc
      181 tttatctttt ttcataaaag gggcatacaa cttagcaaat ttatcctaaa attttttgtt
      241 gcctttatca atcatttcaa cactccttta aatataaaaa tgatcctatc aatctttata
      301 ttgagcctat tttctaattg ataccttgca agaaaggaat aatagctgtt cctataccaa
      361 gtaggaatgt aataaatgca gaaagtcata tactgtcatt cttttctatt aaatcatttt
      421 gaagtgtctc aaagcatcca tgatggcttc ttctttttca ggtgtacact gtggaataat
      481 ttgtttatcc tttttagact tgttgtaatg ttctcgtaat tctattccac atttcttttt
      541 tatctgtgca atatataatg tcgaaacttt taattcaaat ttattccaaa catattcttt
      601 gatttgagca tatgttgctt tgctctccgc acttgtcaaa ttcatctcat ccagctcaat
      661 ttcaacactt atgtgcttat cgacatcgag tttggacaaa agtgctaccg tctcgacgtg
      721 atgcgtttga ggaaatagat ccaccggctg gactttcttc aattcatatc ccaattcttg
      781 gtagagtttg atatcacgcg ccatggttgc tacattgcag gagatatagg cgatgcgatc
      841 ggctcctgtt tgggcgcttg ctttgataaa gctttctgtc aagcccttgc gtggaggatc
      901 aaccaagata acggttggtt gaatcccatc tttaagccaa ttcttcatag cattttcagc
      961 tgtgtcacag acatagtggg cgtttgaaat attgttcagc tgagcatttt ttttactatt
     1021 ctcaaccgct tctggaatca gttcaacacc gtagacttct ttgacatgct tggcgactga
     1081 taaaccaata gttccaatac cagaataggc atcaataatc acatcatctt tttttaactc
     1141 tgcaaagtca atggctgttt gatagagttt ctccgccatt tcagtattga cttggtaaaa
     1201 ggctgggcca gcgatttgga agtcatttcc caacatctgg tccgtaatat agtcttgacc
     1261 ataaagagtg cgccactcct taccaaaaat cgcattggta ttctggtcgt tgatattttg
     1321 catgacagac acaatctctg ggaactgctt gataacttgt tcaatcaatt ggtcaacacg
     1381 aaaaactttt ggacgagttg tcaccaaaac gaccatgatt tgttctgaat agtgaccacg
     1441 acgcaccaca agattccgaa tcaatccaga ctgttccttt tcgtcataag gttttaaatc
     1501 aaaacgacgg agcaggtctc gaagagctac tacgacttgg tcaatgacag gatcctggat
     1561 aaagaaatct tcaaggggca tgaggttgtg cgaattctta cggaaaaatc ctgtttccaa
     1621 gacaccattc actcgacgaa cgggcacctg cgccttattg cgatacttga ctggatgttc
     1681 cataccaagc gtttcagcaa cttctacatc tgcaattcca gcaatcttgt agagactgtt
     1741 cttgacttgc ttggttttaa acttgagctg ttctggataa gaaaggtgtc ctaaatccgc
     1801 gattcctgaa cgcaggtaag ccaaatctag atcttgatta cggtgtggtg actggacaag
     1861 gtatttttca acttttccaa agccaatctt tttattgacc ttgaggacac gcatgagaat
     1921 tttttcactc ggtaaagcat tctctacaaa aaagaccaaa ccatctacct tggcaactcc
     1981 tgccccttca tgggtcaaat caacaatttc aacttctaca atatcatttt tctttaacat
     2041 tcttttctct ttctattggc cgacaaaaaa gacggcaacg ttacggttac catccattat
     2101 accatgaaat ttcttaagaa ccaaaactct tgaagaagtt gacaagggct tgccagaggg
     2161 agcttaagaa gttaccaccg tcctctagcg ccttatccgc atcaaagtta aggttgatat
     2221 ttttaaaact gtcgccagct tgtgatacga tgctttgttt aaggtcattt agggttttag
     2281 tgaaatctgc attgctgagg atatcactct ttgagagatt caaggcaaaa ttgatgatga
     2341 tattgatctg gtttcctgtt atgacctgat caagtttgta attttttaag gtatcttcaa
     2401 caatcttgcg gatatcttct tctgtcagat ttcccttgct ttctttagct ttggcgagtc
     2461 ctgacttgat atcagctagg gcaacgttta atttattagc atcatagcct gatttgtcct
     2521 tgttttcagc attgatatct gacaaagctt ttagctcttc ttgagccaaa tctttattgg
     2581 cttgcggcac cttggctcca ttagcttcta gcgaatagta gatcccagcc aaagcactct
     2641 cacctgtaac tggaatgggt gctgctacag tgattttggc gtgttccaca cccaaagtta
     2701 cggctgcatt tcggtacata tcctgagtta ccttagtgat gttttcaggt gtttcaatct
     2761 tgacctcaag tggcgatttg tcacctagct tttgaatctt ggctgatgaa tacaactgta
     2821 agctagagtc attggccaca ttcatgattt tagaataaac atcaggtgtc atggtcttga
     2881 gttctttggt atctgttgag gcattgtagc ccagtttttt aagagtttga tttttttggt
     2941 cttcagatag ggaggaacct aggacatatt caggttggac ataggtttca tcgataactt
     3001 tttgaacatc tgttgctgca tggacgctat tcatagctgt tactgcccac aagaccgcag
     3061 cactagtcag aaagagtttc tttctcatag ggaatttcct cctttacttc tttagagtaa
     3121 tatatctatc ttaaagaaaa cttataacaa aaacacctgg tctagccaga tgttgaaaag
     3181 agagtgaaac atttgatgat gtaaaggtta agtcgtacct gtctagaata ataatagttt
     3241 cctccattta catagagttc agcaccgtga aaaatggaaa tgggatgaat ataactataa
     3301 gtctttccag tcgtattacc aagcaagggg gcaacagtct cacgagagta ctgtttggct
     3361 agagccaagg tattttcctt gccattttgg gcgataaaat cgatataggc aggtccaaaa
     3421 ttataggctt gaacagctgt ccagatatct acacccttct tctgcgccag atagagattg
     3481 cctgtcagag tttgaatgcc ttgccgaatg ctagaggcat tatcattgat ggtgttggtg
     3541 gaaccacttg cagactcact agactgcata acatcgcctt cttttccttt tgtttcagta
     3601 taaatcatag caagcacaag ctcttcgttt gctggggtgt cttgttcact caagatttct
     3661 cgcaccatgg gttgataggt catgacttgt ttgacatctt gatgaacgcg gtaagcttta
     3721 tagccagcaa aaaggaagac tgctagtaca agcactcttc gaattcgttt aaacattatt
     3781 tactttggat atcctcgata tttttgatta agatagagta ggttccattt tcgttttgga
     3841 taaactcaac agactcggcg tcttgataga cgttattggg aacgatgagc tcaattccat
     3901 ttgataagga gagtttttgg ttttcaaatt tctttaattg gcgactgaca tcaatttcat
     3961 caaattgaac aggttctggt acggcttctt tgacttggtc aataaagctc aaacgagccg
     4021 tcagattgtt gtcaaaaagg tcattagcca atttctcagg tgacaattca ttgctttctt
     4081 ctaggttgtt gaaaatagct gatttgacct tggattgaaa ttgaaaatca tctgtgttaa
     4141 aagattcagc aattctctgg gctgtttttt ccagttcctt gatagatttt ttaggagaaa
     4201 tcttaggagc gacagcaaga agattatctg aaaaatagtt caaaaaagtc ccgttgtact
     4261 tgattcgttt ttcaatcagg tgatacttgc tactctgaag attgaccacc aaggcctcat
     4321 cagctcctgt tccaaatcca ggcaggttat tctgagttag cttgattgga ttatcaactt
     4381 ctcctccgag gtgggtcaag gtctcccgca gggcaattcg caagaaagcg aaatgttcta
     4441 caccttcttt agaaaattga acaaaaatca agtcattggt cttgagattt tcagaaatgc
     4501 taaactcctc tttccagaga ttagccagcg ttactgatgt ctccaacaaa tcgtctgtaa
     4561 tatgattgaa gaagggattt tcttcttcga aaatcccagt cttggcttca tctgaataca
     4621 catgttcaat ttttttacgt aggtattctt cgatttttgg agtaatattg agaaacttat
     4681 ctgctaagaa cagctcggta tcatccggac tgaactggtg aataatggct ttcttaatat
     4741 aaatgtccat aaaagtttta ttcctcgtat aatgggaagg catctgtcaa ttctttgact
     4801 gcacttctca cttcttctaa tacagcctca ttttctgaat tcttaagggt tttaatgatg
     4861 agttcagcca ctttgcgact ttcttcttca ccaaatccac gtgcagtaat agctgctgct
     4921 ccgatacgaa tcccacttgt cttgaatggt gacaaggttt cgtaagggat tgaattttta
     4981 tttagggtaa tattgacttc atccagcaag ttttgagcaa cttttccgtt ttctacaacc
     5041 ttagtcacat caacaaggaa gagatggttt tcagttccac ctgaaataat acggaaatca
     5101 gggtcttgca agaagacatc tgccatagcc ttgctgttct taattacatt ggcagcatat
     5161 tccttgaagg ctggatccaa aacttctttg aaggaaactg ccttagccgc cacaacatgc
     5221 tctaaaggac cgccctgaat acctgggaaa atagctgaat taattttttt agcaagttct
     5281 tcgtcattgg tcaaaatcaa accaccacga ggtccacgaa gggttttgtg ggtcgttgtt
     5341 gttgtgatat gagcgtatgg aactgggctt ggatgaaggc cagccgcaac caaaccagcg
     5401 atatgggcca tgtccaccat gagcttcgca ccgacagcat ctgcgatttc acggaatttt
     5461 gaaaaatcga taatttgaga atatgctgaa gcaccagcta caatcagttt tggttttact
     5521 tcttgggctt gtttcaagat agcatcaaag tctaagagtt ccgtttcagg atcaacacta
     5581 taagaaacaa agttgtaggt ttgaccaggg aagctaacag gagccccatg agtcaaatga
     5641 ccacctgatg ccaaatccat tcccataacc gtatcacctg gctcaatcaa ggatatgtaa
     5701 gccgcacagt tggcctgact tcctgaatgt ggttggacat tggcaaattt agcaccgaaa
     5761 atttcttttg cgcgttcaat agcaagagtc tctacaacgt ctactacatc agttccacca
     5821 taataacggc gtcctgggta accctcggca tatttatttg tcaagataga cccttgagct
     5881 gccataacag ccttggaaac tacgttttcc gaagcaatta actcgatatt attttgttgg
     5941 cgttcttctt ctttggcaat agcattccag agatcagcat catatgcttt aaaatcatct
     6001 ttgtcaaaaa tcataggtct tctcctttat tgtgtgacta gtccattagt ttgattttac
     6061 aataagaaaa tcaaactaaa agatgcgaat aaaccgtttc tgcattttat cacaagtata
     6121 gccaactttt tcataaaatg catgagcacc cagacgatga ttggcagaat ttaagcggat
     6181 aaacccataa ccacatcttt tggcttcttg ttccaaccct tgtagtaaac ttttaccgat
     6241 accttgacct tgcgcttgag gtgaaactgc taaagctaag atattaaatc ctgctttgga
     6301 atagagtgat tcgtaaactt cagcgtggac atatccaagt aagacatgat tagctgcatc
     6361 ctcatagcca agtaggaaat gatgggaatc ctgagacagt ctagctagtt ggctagccgt
     6421 ttcctctgga ctaaaagtat aacccaaagc ctcttggttg atgtcacata tcgctttcac
     6481 atctgtttct tgcaaatctc ttagcatttc aagcctcctc aaaagaaatc tctggcaacc
     6541 gagcaagaat atcttctcgt ttaattgcgc cttggcgtaa gattttcacc ttgtctccag
     6601 acaaatccac aatagttgaa tcctgtccag ttagaaaagc atcgtcttcc agacccagaa
     6661 cctcttggtc aaaatccttt agaatttgat caaaggttac accacttgcc tgacctgaga
     6721 tattggcaga cggcccaatc aagggacctg tctctcgaat taaatccagt gtgatagggt
     6781 gactgggcat ccgaaatcca atagttgcaa ggtcagaatt tacccaatag ggaactcggt
     6841 cattggcttc gagaataatg gtcaagggac ctggcaaaaa ggtctctaca agtttttgta
     6901 gataagctgg ctgattctta gaaaagtgca agatatcctc taaagaggca acattgagat
     6961 tgagcgcctt gtctctagga cgacgtttga gctggtaaac atggtcaact gctttttcgt
     7021 ctaaggcctt ggcaaaaaga ccataaaccg tctctgtagg cagaatgaca gctccaccat
     7081 tttccaactc ttgtctaatc ctgtccatca tcaaccacga ccatcctatc ttgaccaaat
     7141 tggtccttga atgttcgaac ttttttttca ggaagatgtt ttctaaaaag ttcgggaaca
     7201 ctttgacctt gcttgtatcc aatttcaagg taaatcttac caccatcttt gagatagtct
     7261 tttgcatctt ccgcaattct acggtaaata gctaggccat cctcgtctgc aaagagagct
     7321 agatgaggct ccgaatacaa gacattcaag cctacctctg actcatcttc acgagagata
     7381 tagggtggat tggaaacaat tatatcatat ttttcagaaa tttctgtaaa acagtcagat
     7441 tttttaaaaa atatttgaag attttgattt ttagcatttt cgctagctaa atctaaagcc
     7501 tcttgagaaa catctgctgc tgtcactgac caatctggtc tattttttgc tagagcgaga
     7561 gcaatagctc cactacctgt tccaatatcc agaactgaaa gattcgtctc aagattttca
     7621 gttagaataa gctccactaa ctcctctgtt tctggacgag gaatcaaaac ccgttcatcc
     7681 acctttaaat gcattccata aaaatctgcc tgtccaatga tgtactgagc tggcttgtga
     7741 gctgctagtt gctggtaaat atcttctaca aattgttttt cttcctctgt tgtcacctcc
     7801 tgctggaggg caaaaataaa gtctgtaaaa gatagatttt tcagactacg atagacaaaa
     7861 gagaggcttt ccgcttcctc tccttgtctt atcaactctt cttcaaaatt tgaaaataat
     7921 tgagctaatt tcattatttg tttaattctt ctagtttttg tgtttggtca taaagcacca
     7981 aggcatccac aacttcgtcc aatttaccag acaaaatcgt atctagtttt tggagggtca
     8041 agccgatacg gtggtctgtg acacggtttt gtgggaagtt ataagttcgg atccgttctg
     8101 aacggtcacc agtaccgatt gtcgacttac gctcagcgtc ttgttcatcc tgagcaatct
     8161 gagcaaagtg gtcagcgacg cgtgcacgga taatcttcat agccttctcg cggttcttct
     8221 gctgggtacg ttcttcctgc atctcaacct tgatattggt tggcaagtga acgatacgaa
     8281 cggcagtcgc aaccttattg acgttctgtc caccagcacc agaggcgtga tagatgtcga
     8341 cacgaaggtc ttttggatca atgtcgtatt caacctcttc aacttctggc ataacaagaa
     8401 ctgtcgctgt cgaagtatga acacggcctt ggctttctgt cacaggaaca cgttgcacac
     8461 ggtgggcacc tgattcatac ttaagcttag agtatacaga ctgacctgaa accatagcaa
     8521 ccacttcttt aaaaccaccg acaccattca tagaggcttc catgacttca aagcgccaac
     8581 cttgggcttc cgcatacttt tggtacatag ttagcaaatc tccagcgaaa agtgccgctt
     8641 cgtctccacc agctgctcca cggatttcaa ggatgatatt cttgtcatcg tttggatcct
     8701 ttggaaggag caagattttt agtttttctt cgtattcttc tttttcagcc ttggcatctt
     8761 tgagctcttg cttggccatt tcttccaagt ccgcatctcc gcctgattcc ttaatcatct
     8821 cttcagcatc gacgatattt tgaaggactt gtttgtactc acggtaggct gtaaccgtgt
     8881 cacgagttga agcctcttct tttgaaagct ccataaaacg cttggtgtct gaaacgacat
     8941 ccgggtcact gagcaattct cctaattctt cataacggtc ttctacagct tgtagttgat
     9001 cataaatgtt cattttttct ccttatttct caattgttaa aatcgtatat cgctactact
     9061 tcgttctcgt atatttcccc agtttcttta aatccataac tgaggtaaca agatcttgca
     9121 tgttcatttt ctggttcata agacaaccaa agtttattgc ctaaacctgc tgacgctgtc
     9181 cgaacatagt ctagtacttt atccataatt ggtttaaaat atccttgatt ttgaaaattc
     9241 ttatcaatca taaaacgaaa tagtaaataa tttccactac ttattccgat ctttttatca
     9301 taagctatca tcacaaaacc tataattgca tcattatcat aaactgccaa tggagctaca
     9361 aaatctccat ttttagtgta gacatatgct tcagctaaac taattgcgtt ggttgcaatg
     9421 aattgttttt gatatttctt gacatccaaa ttcaaaacat caaaataatt ttccattgta
     9481 acatctctta gttcaattgt catagttttg ctccttgtta gaggttatca ttggcgcaaa
     9541 ataatgttta cggcaaaccg agatataggt ttcattaccg ccaatctgga tctgttctcc
     9601 atcgtaaacg ggcagtccat cctgtgttcg caaaaccata gttgcctttt tcttacaata
     9661 ctgacaaatg gtcttgattt catcaatctt atctgctaaa agcaagagat acttggaacc
     9721 ttcgaacagt tcattgcgaa aatcattttt caaaccaaaa gccatgacgg gtatatctaa
     9781 ctcgtccaca acacgagcta gatcgtaaac atgatgacgt ttgagaaact gggcttcatc
     9841 gaccaacaca cagtaaggtg tttctggtaa atcacggata aatccaaaga tatccgtcgt
     9901 ctcctcaatc gcaagagcag ggcgtttcat accgattcga ctcgacacat agccaacacc
     9961 gtcacgcgta tccagagccg aggtcataat cacaacacct tttccttgct cctcatagtt
    10021 ataggccacc ttgagaatct caatcgtctt acctgagttc atggtcccat aacgataata
    10081 caactgtgcc atgtttcttg cttcacgtcc gtttctaaat ttttgctaca ttctagtata
    10141 tcataatttt ctgaagcttt aaacggcaaa atgtggtaaa atagaagaaa tcaaaaacta
    10201 gtggaggaag ctattatgcc atttgtacgc atcgatttat ttgaaggacg cacgctcgag
    10261 caaaagaagg ctcttgctaa ggaagtaacg gaagctgttg tccgtaacac tggagcccct
    10321 caatctgctg tccatgtcat catcaacgac atgccagaag gaacttactt ccctcaaggt
    10381 gaaatgcgca ccaaataagc tagcttaagc agaattgctt aggctttttc aatctccaag
    10441 tagcattcat tgaagaaata gttcaaattt gttacaattt gaaaagagac ttggagaatt
    10501 ttccaagaaa agagctattg attaaaggaa atattatgat tacacgtgaa tttgatacca
    10561 tcgttgctat ctctactcca ctaggtgaag gggctattgg tattgtccgc ctgagcggaa
    10621 cagacagttt tgctattgcg caaaagattt ttaaaggaaa agacttgaac aaggttgcta
    10681 gccacactct caactacggt cacatcgttg atcctctgac tggtaaagtc atggacgagg
    10741 tcatggtggg agccatgaaa tctccaaaaa ccttcactcg tgaggatatt atcgagatta
    10801 acacccacgg tgggattgcg gtgaccaatg agattctcca gctagctatc cgtgaaggag
    10861 ctcggttggc tgaacctggt gaatttacca aacgtgcctt tttaaacggt cgcgtagatt
    10921 tgacacaggc tgaggcggtc atggatatca tccgcgctaa gacagacaag gccatgaaca
    10981 ttgcggtcaa acaacttgat ggttcccttt ctgatcttat caataatacc cgtcaagaaa
    11041 tccttaacac acttgcccaa gttgaagtca atatcgacta tcctgaatac gatgatgttg
    11101 aggaagctac tactgccgtt gtccgcgaga agactatgga gtttgagcaa ttgctaacta
    11161 atctccttag gacagcccgt cgaggtaaaa ttcttcggga aggaatttca acagctatca
    11221 tcggccgccc caacgttgga aaatctagcc tgctcaacaa cctcttgcgt gaagacaagg
    11281 ccatcgtcac agacattgct gggacaacac gtgatgtcat cgaagaatac gtcaacatca
    11341 acggtgtccc tctcaaattg attgacacag caggtattcg tgaaacggat gacatcgttg
    11401 aacaaatcgg tgtggaacgt tcgaaaaaag ccctcaagga agctgacttg gttcttctag
    11461 tactaaatgc cagcgagcca ctgacagccc aagaccgaca acttcttgag attagccaag
    11521 atacaaaccg cattatactt ctaaataaaa ccgacctgcc agaagcgatt gagacttcgg
    11581 aactacctga agacgttatt cgtatttcag tccttaaaaa ccaaaacatc gataagattg
    11641 aagagcgaat caacaacctc ttctttgaaa atgctggttt ggttgagcaa gacgcaacct
    11701 acctgtccaa tgcccgtcat atttccttga ttgaaaaggc agttgaaagc ttacaagctg
    11761 ttaatgaggg tctagaactg gggatgccag ttgatttgct tcaagtagat ttgacacgta
    11821 cttgggaaat cctcggagaa atcactgggg atgccgctcc agatgaactt atcacccaac
    11881 tctttagcca attctgttta ggaaaataag aaaaatccat gatccttcat tcggtcatgg
    11941 attttattgt ctttattagt aatctggtct taagacacct gttacagttg ccttggtcgc
    12001 ttcgtagtcg ccatctacga caaccttgat aatgcgttta gcatcttctt ctggtgctgg
    12061 aacaagaggt agacgagttg gtccagcttc aaatcccatg tagttcaaaa ctgccttaac
    12121 tggagcagga cttggataag agaagagagc attaacctta ggaatgaatt tacgttgaat
    12181 agctgcggct ttcttcatat cactttctgc aatggcaata aacatctcgt gcatttcatc
    12241 cccatttgta tgagaggcaa cagaaataac cccatccgcc ccaaggttca tggcatggaa
    12301 agcatctcca tcctcaccag tatagaccaa gaactcttct ggtttgtgct caatcaagta
    12361 agccatatta gccaagctag tacattcttt gacaccgata atatttggat gatcagccaa
    12421 gcgaagcatg gtttctggag ttaattcaac aaccacacgc cctggaatgt tatagataat
    12481 aattggtagg tcagaagcat ctgcaatagc cttaaagtgc tgatacatcc cttcttgaga
    12541 aggtttgttg tagtaaggaa caatagcaag cccagctgcg aaaccaccaa attccgctac
    12601 ttctttgaca aactcaatag agtcacgcgt atcattagta cctacacccg caatcaaagg
    12661 aacgcgtcca ttgacaacct tttgtacagc cgcaaacaac tccaactcct catcgtgggt
    12721 caaagttgga ctctcagcag tcgttcctgc gagaagaatt ccatccgtat gatgggccaa
    12781 taaatgctca atcaaggctg gaatagcatc aaagttaatg gaaccatcct catggaaggg
    12841 ggtaataaaa gctgtaatga ttttacattt ttttaaatct tgataagaca cgaaaacacc
    12901 tctctatttc aaagaaggag ttcatctgaa ctcctaaacg atatgactat tttaattcaa
    12961 atttcaattc agctgttgga cgaaccaatc cacgttcatg aagagtttca gcaatctgaa
    13021 ctgagttcca agcagcacct ttgagaaggt tatctgaaac aacccacatg tgaattcctt
    13081 tttctgcatc caagtcttta cggatacgac caacaaaggt atcacgtgaa ccaactgcat
    13141 tgatggcttg aggatagatt tgatgaacta catcatcttc aagaacagca cctgggaagg
    13201 atgcgatagc tgctttgact tcttcaattg gagccacttc ctttgtttca atataaactg
    13261 actcagagtg agctgacaag actggaatac gcacacatgt cgcagatact gcaatgctat
    13321 catcttccat aattttctta gtttccttgg tcatcttcat ctcttcgtac gtgtaatcat
    13381 tatcagtgaa gacatcaatt tgtggaagag cgttaaaggc gataggataa tgtttcttgt
    13441 caccacctga aggcaagatt tccgcatgca aatcacgtgg tttcactcca tcattcaaga
    13501 cctcacgaag ttcacgttgt gtctcaagaa ttgctcccat accagcacct gaaacggctt
    13561 gataagttga aacaatgata cggtccaagc cccatttttg gcgaaccggc tcaagagcca
    13621 ccatcatttg gattgttgaa cagttagggc aggcaatgat tccgttgtgg gcatcaagtg
    13681 catgagcatt gacctctgga acaaccaaag gaacatctgg attttgacgg aaataagatg
    13741 tattatccac tactaccacg ccagctttta ctgcgtatgg tgcatactta gctgatgtcg
    13801 aaccacctgc tgaaaagaga gcaatatcaa ctccttcaaa agctgtttca gtcgtttctt
    13861 caatcgtaat atcttgatct ttaaatttca atgacttacc tgctgaacgt gcagaagcaa
    13921 ggtaacggat tttatcgatt ggaagtgttg attcttccaa catttttatc atctgagcac
    13981 cgacagcacc tgtcgcgccg actacagcaa ctgtatatcc cataaataac ctctttcgga
    14041 attttctaaa aatttctata atagaagtat tatactactt tttccatgaa ttgcaaagct
    14101 ttttcatcat tttttggaaa ataaaaatcc ccaatcgcta gactagggat taagaggcat
    14161 cttcatgtga tgagcaggtt cacacaactc atcaaggtcc gctcctgcgt tatgacctcc
    14221 ttatgctcaa tagtagcccg aagactacct atcgactcat cgcatctact attctactaa
    14281 agagaatgac ttttgtcaac agacgaaact ctttatactc ttcgaaaatc tcttcaaact
    14341 tcgtcagcgt cgccttgccg tatgtatggt tactgacttc gtcagtttca tctacaacct
    14401 caaaaacatg ttttgagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg
    14461 agcaacctgc ggctagtttc ctagtttact ctttgatttt cattgagtat tagttttatt
    14521 tacacaggtg cataagaaat atattggaaa aattgggggc agacataaca aaaacccttg
    14581 taaatcaagg gcttttctgt ctatttaatg ctaattgccg ggattgaacc ggcgacctca
    14641 tccttaccat ggatgcgctc tgccaactga gctaaatcag cttacttaag aagtatacta
    14701 tattcaaaaa aacttgtcaa gtttccttag aaattttcca taggaaaaag ccaggtaaga
    14761 actacctagc ttatcttctt ctatttactt aaatcaattc gacgaccaat tttaccaata
    14821 ataatcgctc caataatcaa tgaagcaaat tcaccgattc ctgttgtaaa ccaagtaagg
    14881 aagaatggta attctgctac aatatttaac tctgcagcga tagtaaacat ggaaattgaa
    14941 aagaggattg aaaagaagaa atgatctttt cgaatcaatc cgttaaagag gtaatccttg
    15001 ctatattttg caaaaagcca aacacctaaa ctgaggaata ctaaggttga accaccacca
    15061 acaaagacat ctagcagtcc gaagctaaag aaattagcaa tcatacaacc gatggtaact
    15121 ccgatgatgt acttaggatt gtaaaaagcc ataaagttca tcatttctga aatacgaaac
    15181 tgataagcac catagctgat ggcatttagg ggcggtgtga cagtcaaaac gacgtagata
    15241 gcagcgacga ttgcaatatc tgcaacatca cgaatagtta attttttcat cttttctcct
    15301 ttggcggtta tccgcgtgta atatgcttgg tgaaagaagc taagcaccaa gggttgattc
    15361 attcaacctt actagtatag cacaatagcc tgctttatgc tatacttaaa gcatgaaaaa
    15421 acctattcaa aaatttttta acaatgaaat cttagcctat ctcttttttg gccttgcgac
    15481 aactctagtt tcgattctct cacgactagt catttatcaa ctaagtcatc aggaactcct
    15541 tgctacggcc ttggcaaata ttatcggtat cttatttgcc tttatcacaa atgatacgat
    15601 tgtatttaag caaaaaaaga aaaatagact tatccgttta gtgaaatttt ctcttgctcg
    15661 cctttctact tttctgttag acttgttttt aacttttctc tttgtaaccc aatttcctca
    15721 catcataggg caattcgtaa ctgaaaacat tgataagata aatgctattg aaacaataat
    15781 tgcacaaata ttcattatta tcatcaatta tatcttgagc aaggtctata tttttagaaa
    15841 ataatgctcc atttatgagc cttttaattg ccttctataa tgatttagga tacaatgaaa
    15901 cacgaaacat tgaaaggaaa acagtatgtt aaaaaatcta aaatcgttct tgcttcgagg
    15961 aaatgttatt gaccttgctg tcggtgttgt cattgcctct gcttttggtg ctatcgttac
    16021 ttcacttgta aacgacatta tcactcctct tattttaaat cccgctttga aagctgctaa
    16081 agtcgaacgt atcgctcaac tttcttggca tggagtcggc tatggtaact ttttaagtgc
    16141 tattatcaat tttatctttg tgggtaccgc cctcttcttt attatcaagg gcattgaaaa
    16201 agcacagaaa ctgactggca taaagaaaga aaaaactgcc gaaaaaaaac caaccgaatt
    16261 ggaagtcctt caagaaataa aagctctcct tgagaaaaaa taatcgatta aaaggatcta
    16321 gcgcaaagct aaatcctttt ttctttactc tttgggtaac ttgcctgctt tttcaagcat
    16381 ttttttgata agataaggca tcttaacatt ctcccgccct tttttctcaa tcagtttttt
    16441 cacaaattct ggcatttgta aatcttcaga ttcagctaaa atgtttttcg tctcgtctga
    16501 aggaactaac tcatcaaagg tctcttcttc tgggagaaat tccttaaact cttgattttc
    16561 attgactcta attgtattga ccaaagcatc aatcaaacga gaatctgtat ttggcattgg
    16621 tggacgatgg tagtttaccc caaattcctg acataagtca taacattcca catcattgtc
    16681 aaacaagacc tcaatatgct cactgatgaa actaataggt acaaaaatat aatggtctgg
    16741 atgttctgtc tgttctctga gatactccaa aacatctggt ttaatccatg gaataccaat
    16801 atcactctca ctctgccaag tgttggtata ttgttctgaa ctcaagccca gtttttcagc
    16861 gactagcttg ctattttcga aaatttggtc tatataagga tcaccaaagt ccaaggcaaa
    16921 aataggcaca ctatgggctg aaaagatgac tttaaagctg tcttgcttta cttcttcttt
    16981 taaaatctta gcaatttcat ctgcccaata gtttaagagc gcttcttcct gataccagtc
    17041 cttaataacc aaaaattgaa tttgtttgct ttctaaaaat ttttcatagc ccatgacaga
    17101 gtagaaagaa taatggggct ccaaaatcaa gcaaatacac tgttcaattc cgtctgcttc
    17161 catttgaccg atcacatctg gaataaaggg actggaaaac ttattagcaa agtagacact
    17221 gtattcattc cccagcctag cttctaccaa ggcaacctct tgacgggtaa ttttttgcag
    17281 aggcgtgcct ccaattcgta cataattatc atagagagtc tgaatctcgt ggtcttgggg
    17341 tctcacccca cgacgaatat ttgtgaaaaa atcagctaca ccttcaaagg taatctcttc
    17401 tggtgaaccg aaggtcatca ttaaaattgc ttttttcatg actgcttcct tgtgatgttt
    17461 ttatcaagtt tattttatca ttaattcatc gataagtaaa cgctaacata gggacattct
    17521 caatcttctg tcttttgttt ttctcttctt tctatgatac aatggaaaaa ataaattcaa
    17581 aaggagtttt tttatgactt atccaaatct cttggaccgc ttcttaacct acgttaaggt
    17641 caacacgcgc tctgatgaac actctactac tactccaagt acacagagtc aggttgactt
    17701 cgcaacaaat gtcctaattc ctgaaatgaa acgtgttgga ctgcaaaatg tttactatct
    17761 accgaatggt tttgctattg gaaccttgcc agccaacgat ccgtctttaa cacgtaagat
    17821 tggttttata tcgcacatgg atactgctga ttttaatgct gaaggagtca atccacaggt
    17881 aattgaaaac tacgatggtg gtgtgattga actagggaat tctggtttca aactcgatcc
    17941 agctgacttc aagagtcttg aaaaatatcc aggacaaacg ctcatcacaa cagatggaac
    18001 aagcttgcta ggtgctgatg acaagtcagg aattgctgaa attatgacag ccattgaata
    18061 tctaactgct catcctgaaa ttaagcactg tgagattcgt gttggttttg gtccagatga
    18121 agaaatcggt gttggtgcca ataaatttga tgcagaagat tttgatgtgg attttgccta
    18181 cactgttgat ggtggtccac taggtgaact tcagtacgag actttctcag ccgctggtgc
    18241 tgaattgcat ttccaaggcc gtaatgtcca ccctggtact gccaaagggc agatggtcaa
    18301 tgcccttcag ctagcaattg attttcataa tcaacttcca gaaaatgacc gacctgagtt
    18361 aactgaaggt taccaaggtt tttaccatct aatagatgtg acaggtagtg ttgaggaggc
    18421 gcgtgcaagc tacatcattc gtgattttga aaaagatgcc tttgaagcgc gtaaagcatc
    18481 catgcaatct atcgctgata agatgaatga agaacttggg agcaaccgtg tcactctcaa
    18541 cttgacagac cagtactaca atatgaaaga agtcattgaa aaagatatga ctccaattac
    18601 cattgctaaa gccgttatgg aagatctagg tatcacgcct attatcgaac caatccgggg
    18661 tggaacagac ggctctaaga tttcctttat gggaatccca actccgaata tctttgcagg
    18721 tggcgaaaat atgcacggac gttttgaata cgttagcctt cagactatgg aacgtgcagt
    18781 tgataccatc attggcatcg tagcttataa aggctaaaaa gacgaggtag ctcagctact
    18841 tcgcctttct ttttattcta ctggtttttc ttgatttcca gtagttgtag aagattctgt
    18901 tgtttcattt tctgaagttg attcagcagg tttagaatct cttgtattgc ttggtttgtt
    18961 ttcgtcgcta gcagtttcaa tgttagattc tgcagttgcg tttggttggt tctcagcact
    19021 ggtgttatca ctatttgctt cagcatttct tgctggactt gtttcttcac ttgcgctagc
    19081 ttttgactgg atttgatgat tcaaaactag aatagctttt gtcgattcaa gtaaagctgt
    19141 tttgtcttta ctcttagcag aaagttgatc taataatgca tccaccttat caaagtccgc
    19201 atcagatcca ttattacttt ctaaataaga gtgaagcgac atgagaatat cgtagagttt
    19261 ttgatagagt acaagtgtct gagaatcttg ctcagcattt tccttttctt gttgaagggc
    19321 gctagcgata cgagtcaaga catcttttac ctgactgttt acttcatcca agtctgcatc
    19381 agccttgttt gtggcagctt ttagattttc tacttcttct gccaaggatt gtctgattcc
    19441 ttcttcatgg atttgttcca agagttgatt tgccttgttc aaaagacttt ctacttcttc
    19501 ctttctatct gtcgcagatt attggttgct atctaccatg tactcctaaa acaggagagt
    19561 tataatccaa gattacaagg ccttacagaa ataagaaatc cagataagac aatgttcgtc
    19621 caagacgcta ttcgcttcgc acagcagcac ggattcaata tactttaatt ttaaagttta
    19681 ggtgtcaaga cctcttttta gtgtgcccaa aatttagaga agtaatcaat caactaactt
    19741 ttattttttt caaactttca gtaaactgac ctaaagctaa ctcaatctgt ctttgtagat
    19801 gcttctgcta tcagctagaa gttgatctac ttttgccaag actgccttct catcaaaagt
    19861 tccaggttga tagttggatt gcagggatgg aatcttgttt ttcaaagccg cttcatatcc
    19921 cttagtttga accttgatgt agtgattgtg gtcgccatga ggaatcacaa aaccttctga
    19981 atcttcactt ataattcgat tggcatcaaa accatgacca tcttcttcct catggtggac
    20041 atgtggtgac ggattactta atacagaact agaagaactt cctacctctt ccgtgttaga
    20101 gtgtgatggg ggattgttaa gagatgactt aggaatatag tgatagtgat ccccatgtct
    20161 tactatataa gcatcacctg tatctctgac aatatcatta gggttaaaga catatgtggc
    20221 tgctaattca cctgccgaca agtcactctc aggaatgaaa tgatagtgac caccatgtgg
    20281 tactatagta gattgaaata gaatatgagc aaattgataa ggggatttta aagtaatttc
    20341 taacaatgat ttagaaacta tgatgtgcta ttctaaattc aactcactat atataaccat
    20401 catcggtagt ataacgtccc tgtaattttg ctacagatac ttctgcacta gctcctttat
    20461 cgtctttacc atgttcttgt ttttggcgat tgatttcatc ttttgttcgt acattttctg
    20521 catgagcttg atctttaagg taaacataat actttccatc taccttaata atatatcctc
    20581 ccttaaccta actgacgata tcttgatctt tcggctgata gttgggggct ttcattaata
    20641 gctcttcact aaagagcgca tcaaaaggaa ctttaccatt atagtagtga taatgatcgc
    20701 catgagaagt tacataacct tgatctgtaa tcttaataac aatttgtttt gcttgaattc
    20761 cttctttttg actaacctag tctggagtca aattttcagt cttcttagtg tctttattac
    20821 tgtttacata tgaaacacga tttttatctg tattggcctg ttagctatgt tggttcagag
    20881 cataaacaca cagacttaag gaaaggataa caac
//
LOCUS       DAVLMQ010000032        20387 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000032 DAVLMQ010000000
VERSION     DAVLMQ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20387
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.032"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            108..1058
                     /gene="rsmH"
                     /locus_tag="VXF95_001446"
     CDS             108..1058
                     /gene="rsmH"
                     /locus_tag="VXF95_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HEV1081982.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQQRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQEASLTAYEVVNHYDYHDLIRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKSAKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMEMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            1070..1387
                     /gene="ftsL"
                     /locus_tag="VXF95_001447"
     CDS             1070..1387
                     /gene="ftsL"
                     /locus_tag="VXF95_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HEV1081983.1"
                     /translation="MAERMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            1391..3643
                     /locus_tag="VXF95_001448"
     CDS             1391..3643
                     /locus_tag="VXF95_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PASTA domain-containing protein"
                     /protein_id="HEV1081984.1"
                     /translation="MKWTKKVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAVFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGSKGNGITY
                     ANMMAIKKELETAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGKDGIITYEKDRLGNIVPGTEQVSQQTVDGKDVYTTISSTLQSFMETQ
                     MNAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGLTKDFVWRDILYQSNYE
                     PGSTMKVMTLAAAIDNNTFPGGEVFNSSELKVADATIRDWDVNEGLTGGGMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGIPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFITALYDPNNQSVRKSQKEIVGNPVSKDAA
                     SQTRTHMVLVGTDPRYGTMYNHSTGKATVNVPGQNVALKSGTAEIADEKNGGYLVGST
                     NNIFSVVAMNPAENPDFILYVTVQQPEHYSGIQLGEFANPILERAVAMKDSLNLQSTA
                     KTLDQVTNQSAYAMPSIKDISPGDLAEALRRNIVQPIVVGTGTKIKESSVEEGSNLAP
                     NQQVLLLSDKAEEVPDMYGWTKATAEAFSKWLNIELVFEGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            3645..4625
                     /locus_tag="VXF95_001449"
     CDS             3645..4625
                     /locus_tag="VXF95_001449"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HEV1081985.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIKFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLIASVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGVVFYLFYERGGDMLSVFGYQVHLGIFYILFALFWLVGF
                     SNAVNLTDGIDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFVFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
     gene            5234..7339
                     /locus_tag="VXF95_001450"
     CDS             5234..7339
                     /locus_tag="VXF95_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1081986.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELEKKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
     gene            complement(7635..8117)
                     /locus_tag="VXF95_001451"
     CDS             complement(7635..8117)
                     /locus_tag="VXF95_001451"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HEV1081987.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
     gene            complement(8212..9696)
                     /locus_tag="VXF95_001452"
     CDS             complement(8212..9696)
                     /locus_tag="VXF95_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HEV1081988.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIVTGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            9849..11459
                     /locus_tag="VXF95_001453"
     CDS             9849..11459
                     /locus_tag="VXF95_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001156816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HEV1081989.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDFLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLAQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEEINVQEALANSDSIFYTYQKL
                     IQIRKENSWLIRADFKLLDTADKVFAYIRKDGDRRFLVVANLSNDKQNFSVDGKVRSV
                     LIENTAAKEVLEKQVLTPWDAFCVEMTD"
     gene            complement(11537..12371)
                     /locus_tag="VXF95_001454"
                     /pseudo
     CDS             complement(11537..12371)
                     /locus_tag="VXF95_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(12319..13704)
                     /locus_tag="VXF95_001455"
                     /pseudo
     CDS             complement(12319..13704)
                     /locus_tag="VXF95_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677226.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
     gene            13881..15326
                     /locus_tag="VXF95_001456"
     CDS             13881..15326
                     /locus_tag="VXF95_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1081990.1"
                     /translation="MSRRFKKSGSQKVKRSVNIVLLTIYLLLVCFLLFLIFKYNILAF
                     RYFNLVVTALVLLVALVGLLLIIHKKAAKFTIFLLVLSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSEIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNIDLT
                     VNQSSSYLATYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADG
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDIHYYVRLNFTSFLKLIDLLGGVDVYNDQ
                     DFTSLHGKFHFPVGNVHLDSEQALGFVRERYSLADGDHDRGRNQQKVIAAILQKLTSS
                     EALKNYSMIIDSLQDSIQTNMPLETMINLVNAQLESGGTYKVNSQDLKGRGRTDLPSY
                     AMPDSNLYMMEINDSSLASVKTAIQDVLEGR"
     gene            15328..16059
                     /locus_tag="VXF95_001457"
     CDS             15328..16059
                     /locus_tag="VXF95_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HEV1081991.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLTEAYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVASDLVIAYGAEIYYTPDVLGKLEKNRIPTLNNS
                     RYALIEFSMNTPYRDIHSALIKILMLGITPVIAHIERYDALENNEKRVRELINMGCYT
                     QVNSSHVLKSKLFGEPYKFMKKRAQYFLERDLVHVIASDMHNVDSRPPHMAEAYDLVS
                     QKYGETKAQDLFIDNPRKIVMDQLI"
     gene            16068..16760
                     /locus_tag="VXF95_001458"
     CDS             16068..16760
                     /locus_tag="VXF95_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein CpsC"
                     /protein_id="HEV1081992.1"
                     /translation="MKEQNTIEIDVFQLLKTLWKNKLIILLVALVTGAGAFAYSIFIV
                     KPEYTSTTRIYVVNRNQENKPGLTNQDLQAGTYLVKDYHEIILSQDVLEKVATNLKLD
                     IPVKTLTSKVQVTVPADTRIVSISVKDKQPEEASRIANSIREVAAEKIIAVTRVSDVT
                     TLEEARPATTPSSPNVRRNTLVGFLGAAAVTVITVLLIELFDTRVKRPEEVEDVLQMP
                     LLGVVPDFNKMK"
     gene            16770..17459
                     /locus_tag="VXF95_001459"
     CDS             16770..17459
                     /locus_tag="VXF95_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HEV1081993.1"
                     /translation="MPTLEISQAKLELAKKTEEYYNALCTNLQLSGDDLKVFSISSVK
                     AGEGKTTTSTNIAWAFAHAGYKTLLIDADMRNSVMSGVFKSRERITGLTEFLSGTTDL
                     SQGLCDTNVENLFVIQAGSVSPNPIALLQSKNFSTMLGTLRKYFDYIVVDTAPIGIVI
                     DAAIIMQKCDASILVTKAGETKRRELQKAKEQLEQTGKSCLGVVLNKFDTSVDKYGFY
                     GSYGSYRKQKK"
     gene            17474..18835
                     /locus_tag="VXF95_001460"
     CDS             17474..18835
                     /locus_tag="VXF95_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HEV1081994.1"
                     /translation="MNEKLAKSSVAIVQSFLVILLTYLLSAVRETEIVSTTAIVLYIL
                     HYFVFYISDYGRNFFKRRYLIELVQTLKYILFFALAISISNFFLEDRFSISRRGMIYF
                     LLLHVFLVYMLNLFIKWYWKRAYPNFKGSKKVFLLTATSHVEKVLDRLIESDDVVGEL
                     VAVSVLDKPDFQHDDLKVVAEGEIVNFATREVVDEVFINLPSEKYNIGELVSQFETMG
                     IDVTVNLNAFDWARNKQICEMAGLNVVTFSTTFYKTSHVIAKRVIDIIGSLVGLILCG
                     LVSIVLVPLIRKDGGSAIFAQTRIGKNGRHFTFYKFRSMCVDAEDKKRELMEQNTMQG
                     GMFKVDDDPRITKIGHFIRKTSLDELPQFYNVLKGDMSLVGTRPPTVDEYEHYTPEQK
                     RRLSFKPGITGLWQVSGRSEIKNFDEVVKLDVVYIDGWTIWKDIEILLKTVKVVLMKD
                     GAK"
     gene            18867..20045
                     /locus_tag="VXF95_001461"
     CDS             18867..20045
                     /locus_tag="VXF95_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1081995.1"
                     /translation="MKKSVYIIGSKGIPAKYGGFETFVEKLTEYQKDGNIQYYVACMR
                     ENSAKSGFTADTFEYNDAICYNIDVPNIGPARAIAYDIAAVNKAIEIAKKNKDEAPIF
                     YILACRIGPFIARLKKKIQAIGGTLFVNPDGHEWLRAKWSLPVRKYWKFSEQLMVKYA
                     DLLVCDSKNIEKYIQNDYKQYQPKTTYIAYGTDTSPSILKSEDLKIRSWYQEKGLSEN
                     GYYLVVGRFVPENNYETMIREFIKSKSKKDFVLITNVEQNKFYDQLLQETGFDKDPRV
                     KFVGTVYDQELLKYIRENAFAYFHGHEVGGTNPSLLEALASTKLNLLLDVGFNREVGE
                     DGAIYWRKDNLHKVIEESEQKTIEEIKEIDILSTEQVEKRFTWDFIVNEYENLFLLGK
                     "
BASE COUNT         6061 a         3662 c         4578 g         6086 t
ORIGIN      
        1 taaagtgtca agtatttttg acatattttt tgaagaaata ttagcgctct tgtctgattt
       61 gtctgactag tgcaagctgg tcagatttgt ggtaaaatag ataagatatg acaaaagaat
      121 ttcatcatgt aacggtctta ctccacgaaa cgattgatat gctcgacgta aagcctgacg
      181 gtatctacgt tgatgcgact ttgggtggag caggccatag cgagtattta ttaagtaaat
      241 taagtgaaaa aggccatctc tatgcctttg accaggatca gaatgccatt gacaatgcgc
      301 aacaacgctt ggcaccctac attgaaaagg gaatggtgac ttttatcaag gataacttcc
      361 gtcatttgca ggcacgtttg cgcgaagctg gtgttcagga aattgatggc atttgttatg
      421 acttgggagt gtctagtcct caattggacc agcgtgagag aggtttttct tataagaagg
      481 atgcgccact ggacatgcgc atgaatcagg aagctagtct aacagcctat gaagtggtga
      541 accactatga ctatcatgac ttgattcgta ttttcttcaa gtatggagag gacaaattct
      601 ctaaacagat tgcgcgtaag attgagcaag ctcgagaagt caaacctatc gagactacga
      661 ctgaattggc agaaattatc aagtcggcca aacctgccaa ggaacttaag aagaagggtc
      721 atcctgccaa gcagattttc caggctattc gaattgaagt caatgatgaa ctgggagcgg
      781 cagatgagtc catccagcag gctatggaga tgttggctct ggatggtaga atttcagtga
      841 ttacctttca ttccttggaa gaccgcttga ccaagcaatt gttcaaggaa gcttcaacgg
      901 ttgaagttcc caaaggtttg cctttcatcc cagatgatct caagcctaag atggaattgg
      961 tgtcccgtaa gccaatcttg ccaagtgcag aagaattaga agccaataac cgctcgcact
     1021 cagccaagtt gcgcgtggcc agaaaaattc acaagtaaga ggaaaaaaga tggcagaaag
     1081 aatggaaaaa acaggtcaaa tactacagat gcaacttaaa cggttttcgc gtgtggaaaa
     1141 agctttttac ttttccattg ctgtaaccac tcttattgta gccattagta ttatttttat
     1201 gcagaccaag ctcttgcaag tgcagaatga tttgacaaaa atcaatgcgc agatagaaga
     1261 aaagaagacc gaattggacg atgccaagca agaggtcaat gaactattac gtgcagaacg
     1321 tttgaaagaa attgccaatt cacacgattt gcaattaaac aatgaaaata ttcgaatagc
     1381 ggagtaagat atgaagtgga caaaaaaagt aatccgttat gcgaccaaaa atcggaaatc
     1441 gccggctgaa aacagacgca gagttggaaa aagtctgagt ttattatctg tctttgtttt
     1501 tgccgttttt ttagtcaatt ttgcggtcat tattgggacg ggcactcgct ttggaacgga
     1561 tttagcgaag gaagctaaga aggttcatca aaccacccgt acagttcctg ccaaacgtgg
     1621 gactatttat gaccgaaatg gagtcccgat tgctgaggat gcgacatctt ataatgtcta
     1681 tgcggtcatt gatgagaact ataagtcagc aacgggtaag attctttacg tagaaaaaac
     1741 acaatttaac aaggttgcag aggtctttca taagtatctg gacatggaag aatcctatgt
     1801 aagagagcaa ctctcgcaac ctaatctcaa gcaagtttcc tttggttcga agggcaatgg
     1861 gattacctat gccaatatga tggctatcaa aaaagagttg gaaactgcag aggtcaaggg
     1921 gattgatttt acaaccagtc ccaatcgtag ttacccaaac ggacaatttg cttctagttt
     1981 tatcggacta gctcagctcc atgaaaatga agatgggagc aagagtttgc tgggaacttc
     2041 tgggatggag agttccttga acagtattct tgcagggaaa gacggtatta ttacctatga
     2101 aaaagatcgt ctgggtaata ttgtccccgg aacggaacaa gtttcccaac aaacggtaga
     2161 tggcaaggat gtttatacaa ctatttccag cacccttcag tccttcatgg agacccagat
     2221 gaatgccttt caagaaaaag taaaaggcaa gtatatgacg gctaccttgg tcagtgctaa
     2281 aacaggggaa attcttgcaa caacgcaacg gccgaccttc gatgctgata ctaaggaggg
     2341 gctgactaag gactttgttt ggcgtgatat cctctatcaa agtaactatg aaccagggtc
     2401 aaccatgaag gtcatgactc tcgctgctgc tattgataat aacactttcc caggaggaga
     2461 agttttcaat agtagtgagt taaaagtagc agatgctact atccgagatt gggacgtcaa
     2521 tgaaggatta actggcggag gaatgatgac cttttctcaa ggtttcgcgc actcaagtaa
     2581 cgttgggatg acgcttcttg agcaaaagat gggagatgct acctggcttg attatctcaa
     2641 tcgctttaaa tttggtattc cgactcgttt tggcttgacg gatgaatatg caggtcaact
     2701 tccagctgac aatattgtca atatcgctca gagttcattt ggacaaggga tttcagtaac
     2761 tcaaacacaa atgattcgtg cctttacagc cattgccaat gatggcgtca tgttggagcc
     2821 taaatttatt acggccttgt atgacccaaa taaccaatct gttcgtaaat ctcaaaaaga
     2881 aattgtaggg aatcctgttt ctaaggatgc ggcaagtcaa actcggactc atatggtctt
     2941 agtaggaacg gatcctagat atggaactat gtataatcat agtacaggaa aagcaactgt
     3001 caatgttcca ggtcaaaatg tagccctcaa gtctggtaca gccgaaatcg ctgacgagaa
     3061 aaatggaggc tacttggttg gttctaccaa caacattttc tcagttgtgg ctatgaaccc
     3121 tgccgaaaat cctgatttta tcttgtatgt gacggtccaa caacctgaac attattcagg
     3181 tatccagttg ggagaatttg ccaatcctat cttggaaaga gcagtggcca tgaaagattc
     3241 ccttaacctc caatctaccg ctaaaacgtt agatcaggta accaatcaaa gcgcttatgc
     3301 catgcctagc atcaaggata tttcacccgg tgatttggcg gaagccttac gtcgcaatat
     3361 tgtgcaacca atcgttgtag gaacaggaac aaagattaaa gaatcatctg tagaagaagg
     3421 aagcaatctt gctcctaacc agcaagttct tctcttatct gataaagcag aggaagttcc
     3481 agatatgtat ggttggacaa aagcaaccgc agaagctttt tctaagtggt taaatataga
     3541 acttgtattt gaaggttcgg gctctactgt tcagaagcaa gatgttcgtg ctaatacagc
     3601 aatcaaggac attaaaaaaa ttacattaac tttaggagac taatatgttt atttccatca
     3661 gtgctggaat tgtgacattt ttactaactt tagtaggaat tccggccttt atcaaatttt
     3721 atagaaaggc gcaaattaca ggccagcaga tgcatgagga tgtcaaacag catcaggcaa
     3781 aagctgggac tcctacaatg ggaggtttgg ttttcttaat tgcttctgtt ttggttgcct
     3841 tcttttttgc cctatttagt agccaattca gcaataatgt aggaatgatt ttgttcatct
     3901 tggtccttta tggacttgtc ggatttttag atgactttct caaggtcttt cgtaaaatca
     3961 atgaggggct gaatcctaag caaaaattgg ctcttcagct tttaggtggg gtcgttttct
     4021 accttttcta tgagcgtggt ggcgatatgc tttcagtctt tggttaccaa gtgcatctag
     4081 ggattttcta tattcttttt gcccttttct ggctagtcgg tttttcaaat gcagtcaact
     4141 tgacagacgg aattgatggt ctggctagta tttctgttgt gattagtttg tctgcctatg
     4201 gagttattgc ctatgtgcaa ggtcagatgg atatccttct agtgattctt gccatgattg
     4261 gtggtctgct tggtttcttc gtctttaacc ataagcctgc taaggtcttt atgggtgatg
     4321 tgggaagttt ggccctaggt gggatgctgg cagctatctc tatggctctc caccaagaat
     4381 ggactctctt gattatcgga attgtgtatg tttttgaaac aacttctgtt atgatgcaag
     4441 tcagttattt caaactgaca ggtggtaaac gtattttccg tatgacgcct gtacatcacc
     4501 attttgagct tgggggattg tctggtaaag gaaatccttg gagcgagtgg aaggttgact
     4561 tcttcttttg gggagtggga cttctagcaa gtctcctgac cctcgcaatt ttatatttga
     4621 tgtaagaatg gcaccctgat gtttcagggt gtttttgtgt ttaaatacac aatgaaaatc
     4681 aaagaacaaa ctagaaagct aactttaggc tgctcaaaat atagtagatt gaaactagaa
     4741 tagtacacat ctacttctaa aatattgtta gaaatcgatt tgactgtcct gattgatttg
     4801 tcctgttctt atttcgtttt aatatacagt tttgagatgg ttgatagaac tgacgaagtc
     4861 agctcaaaac acggttttga ggttgtagat aaggagaagc tgatgtggtt tgaagaggtt
     4921 ttcgaagagt gtaaaaaaat attggtcagt taaagtcaaa actcttgacc ttttctgacc
     4981 aatgtagtat attatgaacg taaggtaaat gaaagcctta ctagaacact tatttaaagt
     5041 aaaatagaaa gaggtgggtc tatgtttcat ctagaaatct tcagaagtaa agatagtcta
     5101 ctcctgcttg aaaaagaaaa accagaaata gtacgtaggg tagcgatcta gctagtctaa
     5161 attttttaaa acaatggtca aagatagtca atatcagtaa tcataactaa gtaaacaaaa
     5221 agaggtaaag aatatgaata acaactttaa taattttaat aacatggatg atttatttaa
     5281 ccaattgatg ggtggtatgc gaggatacag ttctgaaaat cgccgttact taattaatgg
     5341 acgcgaagtc acacctgagg aatttgctca ctatcgtgcg actggtcaat taccaggaaa
     5401 tgcagaaact gatgtgcaaa tgccacaaca ggcatcaggt atgaaacaag acggtgtcct
     5461 tgcaaaacta ggtcgaaact taacagcaga agcgcgtgag ggcaagttgg atcctgttat
     5521 cggacgaaac aaggaaattc aagaaacatc tgaaatcctc tcacgccgca ccaagaacaa
     5581 tcctgttttg gtcggagatg caggtgttgg taagacagca gttgtcgaag gtctagcgca
     5641 agccattgtg aacggagatg ttcctgctgc tatcaagaac aaggaaatta tttctattga
     5701 tatctcaggt cttgaggctg gtactcaata ccgtggtagc tttgaagaaa atgtccaaaa
     5761 cttagtcaat gaagtgaaag aagcagggaa tattatcctc ttctttgatg aaattcacca
     5821 aattcttggt gctggtagca ctggtggaga cagtggttct aaaggacttg cggatattct
     5881 caagccagct ctctctcgtg gagaattgac agtgattggg gcaacaactc aagacgaata
     5941 ccgtaacacc atcttgaaga atgctgctct tgctcgtcgt ttcaacgaag tgaaggtcaa
     6001 tgctccttcg gcagagaata cttttaaaat tcttcaagga attcgtgacc tctatcaaca
     6061 acaccacaat gtcatcttgc cagacgaagt cttgaaagca gcggtggatt attctgttca
     6121 atacattcct caacgtagct tgccagataa ggctattgac cttgtcgatg taacggctgc
     6181 tcacttggcg gctcaacatc cagtaacaga tgtgcatgct gttgaacgag aaatcgaaac
     6241 ggaaaaagac aagcaagaaa aagcagttga agcagaagat tttgaagcag ctctaaacta
     6301 taaaacacgc attgcagaat tggaaaagaa aatcgaaaac cacacagaag atatgaaagt
     6361 gactgcaagt gtcaacgatg tggctgaatc tgtggaacga atgacaggta tcccagtatc
     6421 gcaaatggga gcttcagata tcgaacgttt gaaagatatg gcccatcgct tgcaagacaa
     6481 ggtgattggt caagataagg ccgtagaagc tgtagctcgt gctatccgtc gtaaccgtgc
     6541 tggttttgat gaaggaaatc gcccaatcgg cagcttcctc tttgtagggt ctactggggt
     6601 tggtaagacg gagcttgcta agcaattggc actcgatatg tttggaaccc aggatgcgat
     6661 tatccgtttg gatatgtctg aatacagtga ccgtacagct gtttctaagc taattggtac
     6721 aacagcaggc tatgtgggtt atgatgacaa tagcaatacc ttaacagaac gtgttcgtcg
     6781 caatccatac tctatcattc tcttggatga aattgaaaag gctgatcctc aagttattac
     6841 ccttctcctc caagttctag atgatggtcg tttgacagat ggtcaaggaa atacagtaaa
     6901 cttcaagaac actgtcatta ttgcgacctc aaatgctgga tttggctatg aagccaactt
     6961 gacagaagat gcggataaac cagaattgat ggaccgtttg aaacccttct tccgtccaga
     7021 attcctcaac cgctttaatg cagtcatcga gttctcgcac ttgactaagg aagacctttc
     7081 taagattgta gatttgatgt tggctgaagt taaccaaacc ttggctaaga aagacattga
     7141 cttggtagtt agtcaagcgg ctaaagatta tatcacagaa gaaggttacg acgaagtcat
     7201 gggggttcgt cctctccgtc gcgtggttga acaagaaatt cgtgataagg tgacagactt
     7261 ccacttagat catttagatg ctaaacatct ggaagcagat atggaagatg gcgttttggt
     7321 tattcgtgag aaagcctaag atagaatttt gaggataaaa aagaaggagc cagctgaaaa
     7381 aaactggttc ctttttaggt acgacaggca tgtcgtatag tagaagtgta ttattccagt
     7441 ttcaatatac tatagtagct cagaagtcgg tacttaaacg tgctatatca aaaccagtcc
     7501 ttgaaaaacg tggactggtt tcgtgtttgg attattacct tgaacgacat gcgttaaaag
     7561 ttagttgaac cgccgtatgc cgaacggcac gtacggtggt gtgagagggg ctagagatta
     7621 tcccctactc gattttaaat cacatgacgt tcaaaggcat catctgaaat cccttgttcc
     7681 aagatgagtt ttgcccattc tttagcagag aagaggctgt ggtccttgta gtttccgcaa
     7741 gattcgatgg ttgtccctgg gacatcttcc caagtagtag tttcagcgat ttccttgagc
     7801 gaatccttga taacagctgc aattttagca ctggtgtgac gtccccacat aatcatgtgg
     7861 aagcctgtgc ggcaaccaaa tggcgaacag tcaatcatgc cgtcaatgcg ggtacggatg
     7921 agtttggcta agaggtgctc gatagtgtga aggccggcgg tagggatgga gtcttcgttt
     7981 ggttgcacca agcgaatatc ataattggag atgatgtctc cttttggtcc tgtttcttcc
     8041 ccaatcaagc gaacataggg tgctttgaca atggtgtggt caagttcaaa actttcgaca
     8101 ataacttctt ttgacatggt aaatcctttc agttttcttc tctcattata tcataaaggt
     8161 tgctcctgag acagagagaa aacctctccg aggctggaga ggttgaaatc tttacttacg
     8221 atataagcgg tcgtattggt agtatgggtc aaaggttacg ttgataccca gtttacgaag
     8281 gacattcttg tcttcatcag tcaagatgat ggttgagtgg gcttcgcttc ctttgaggtt
     8341 gccgagttct tccatagcgc gggcagcatc aggattttct gtagctgtga tagcaagtgc
     8401 aatcaggatt tcatttgaat gaaggcgtgg attgcggcta ccgagatgat cgattttaag
     8461 accttggatt ggcttaacaa cttccggctc gattaatttt acttctttag cgatgtcagc
     8521 tgattttttg atggcgttga tcaaggcagc ggctgtaggc ccaaagagtt ctgagttctt
     8581 accagtgacg atttccccat ttggcaattc aaaggctagg gctggtccac cagtttcttc
     8641 tgctttttgg cgcgcaacga cagcaacctt acggtctgca ggtgtgatac cgaggtcgtt
     8701 catgagcaac tcaattttct tgacggcagc ttcgccaact ttttcagctt tgaagtcaag
     8761 aactgtttga tagtaacggc ggatgatttc ttgtttagaa gcttcgacag cagcctcgtc
     8821 atctgtaata gcgaaaccaa ccatgttgac acccatatct gtcggtgaag cgtatggtga
     8881 ttttccgaga atacgttcca acatgcgctt gagcactggg aagatttcga tatcacggtt
     8941 gtagttgaca gtggtttctc cataggtttg aagatggaag gggtcaatca tgttgacatc
     9001 atcaaggtca gctgtggcag cttcataagc caagttaact ggatgatgaa ggggaagatt
     9061 ccaaacaggg aaggtttcaa atttagcgta gccagatttg atgccattga tttggtcgtg
     9121 atacatattg gacatacacg ttgccaattt tccagaacca ggtccaggag cggttacgac
     9181 aatcaagttg cgactggttt tgatgtagtc gtttttgccc atgccttctg gggaaatgat
     9241 gtgatccata tccgtcggat atcctttgat tggataatga agataagaat caattccgtt
     9301 tttctcaagt tggttgcgga aggcatctgc agcgggttgg ccagcgtatt gtgtaatgac
     9361 aacggaacca acaaaaatcc ctaattcatt gaatttgtca atcaaacgaa gaacttcttg
     9421 gtcataagaa atgcctaagt cgccacgtgc tttggaatgt tcaatgttgc tagcattaat
     9481 ggcaatcaca acctcaacct gctctttcaa ttcttgcaag agcttgattt tgttgtcagg
     9541 ttcataacca ggaaggacac gagcagcgtg gaaatcttct aacattttac cgccaaactc
     9601 taagtagagc ttgccgtcaa attggttaat gcgctccaaa atatggtcgc gttgtaaatt
     9661 caaatattgt tcagaactaa aagcttgttt tttcattttt ttacctctgg actctattat
     9721 aataaaaaat tggaagttag gaaactacgg agctaaaaaa gaaattaaaa agattaagca
     9781 aacgcttgca caaaatttta aaaagtgcta tcatagacta tagattatga aaataatgag
     9841 gtaaacagat gcaagaaaaa tggtggcata atgccgtagt ctatcaagtc tatccaaaga
     9901 gttttatgga tagtaatgga gatggaattg gcgatttgcc aggaattacc agtaagttgg
     9961 actatctagc caagctagga atcacagcaa tttggctttc tcccgtttat gacagcccta
    10021 tggatgataa tggctacgat attgctgatt atcaagcgat tgcaacgatt tttggaacca
    10081 tggaggatat ggatcaactg attgcagaag ctaagaagcg tgatatccgt atcatcatgg
    10141 acttggtggt caatcatacc tcggatgagc atgcctggtt tgtagaggcc tgtgaaaatc
    10201 ctaatagccc tgagcgagac tactatatct ggcgcgatga acccaatgac ctagattcta
    10261 tctttagtgg gtctgcttgg gaatacgatg aaaagtcagg tcaatactat ctccactttt
    10321 tcagcaagaa acagccggat ctcaactggg aaaatgaaaa acttcgccag aaaatttatg
    10381 agatgatgaa cttctggatt gataaaggta ttggtggttt ccgtatggat gttattgaca
    10441 tgattggcaa aattcctgac gagaaggtag tcaataatgg tcctatgctc catccctatc
    10501 tcaaggaaat gaatcaggcg acctttggag ataaggattt cttgacagta ggggagactt
    10561 ggggagcaac gccagagatt gccaagctct actctgatcc aaaggggcaa gaattgtcta
    10621 tggtcttcca gtttgaacat atcggtcttc agtatcagga aggtcagcct aaatggcact
    10681 atcaaaaaga gctgaatatc gctaagttaa aagaaatctt caacaaatgg cagacagagt
    10741 taggagttga ggacggctgg aattccctct tctggaacaa ccatgacctc cctcgtattg
    10801 tctcaatctg gggaaatgac caagaatacc gcgaaaaatc tgccaaagcc tttgcaatct
    10861 tacttcatct catgagagga actccttata tctaccaagg tgaggagatt gggatgacca
    10921 actatccgtt tgaaacactg gctcaagtag aagatattga atctctcaac tatgcgcgtg
    10981 aggctcttga aaaaggtgtt ccgattgaag aaatcatgga cagtatccgt gttattggac
    11041 gtgacaatgc ccgtacccct atgcaatggg acgagagcaa aaacgctggt ttctcaacag
    11101 gtcaaccttg gttggcggtt aatccaaact acgaagaaat caacgttcaa gaagcactgg
    11161 caaactcaga ttctattttc tatacctatc agaaactcat ccagattcgt aaggaaaaca
    11221 gctggttgat tcgagctgat tttaaattac tcgatacggc tgataaggtc tttgcttata
    11281 tccgtaagga cggtgaccgt cgcttcctag tcgtggctaa tttatccaat gataaacaaa
    11341 acttttcagt agatggaaaa gttagatctg tcttgattga aaacactgcg gctaaagaag
    11401 tacttgaaaa acaggtcttg actccatggg atgctttctg tgtggaaatg actgactaga
    11461 atgagcaaga gcctgggaca aaatagttct cgaccacaaa aaagctagag atttccaatt
    11521 gtggaactct agctttttaa ttttgagtca ttctcttatt gtattttagg aggttattgg
    11581 ccataagtac caatcccatg tcaattctca cttgacgctt gcccctcaga ttacatctct
    11641 tgtaacccaa acaagccttt atctgcccaa agacaggttc cacatcaatc ttgcgttgag
    11701 cgaaaatctg tctaccttgg ggagataaaa gcgcctgaca ttctttagct ttcaagtttt
    11761 gatagccttc gttcatatac agtccccttt tgaggggctg attcaggttc gtcgacgtag
    11821 taaaccttga tttcttgttg aaagtctgtc tgtgttttct gatgtttggt atggtgaaaa
    11881 cgataatact agccatcagg atgtgtatag ctatcctcct tgtcattata gtgccaattc
    11941 gctaagtttc tagctgactg tttatagcct ctcttctgtt ccttatcaaa catggcatat
    12001 ttaatcagat ggtttacctc cttttcatct aaacgaagga ggttctcttc acttccatat
    12061 ccagcatctg cgacaactgt cttcaagtca tgcggatagg tttcaaggaa tggcagaaga
    12121 gtcttggtat ctgtcggatt tgaaaagaca tcatagtgaa gaacaaattg gttttccgta
    12181 gcgatttgaa gattataagc agccttgggt tgactatttt tcatatgttc ttccttcatc
    12241 cgcataaaag tggcatctgg atcggttttg gaaaaactgt taggcccttg aaatgtctcc
    12301 tgatagttct catatttttc agcacgtact gaaaaatcct cctttaaact cttcataatc
    12361 ctttttattt ttatgaagat attgtttgaa agatgtgagt ttccacggat gggtttgtgg
    12421 agggatatac ttgcgtcttt ctttttttgt tctggttctt gttcaaggtt tttcgaatag
    12481 agttcatgat ttagtagctc ctttgtgtga tagattttgt cagcgatatt gaggtagatg
    12541 tcaccatcaa atgcttttat aactaatgct tttgtctttc tgatgaaata gacttctttt
    12601 ccttgctcgg tagggatata gcaacgattt tggaatcgga tatggtgtcc actatcgacg
    12661 actctctccc gccagtttag ctagaatgag atttcgttca gagggcttag gagcctcctc
    12721 aaagacagag agttttgtct tgtttccaaa ctgttcatta aaggtttgga tataggaagg
    12781 cagaaaggta ttggcttctt ccaaggtatg aatcttgttt cgttccagtt cgataggcag
    12841 gagagattgt agtatctgat tgagtctttc gactctccct ttagcttgag ggatagaggt
    12901 tgtctcaagg agaattccca gttggtgaca ggcgtatcca aattgtgtat gggtgtcgtc
    12961 ctccattttc ttagagttgg aggcttgata ggtaaaaaca gttctcttat ctgttttgat
    13021 ttgaacagga atgccgtggt tggctaagat ttgttcgagg acatgatagt aagcattcaa
    13081 ggtctcttgt ttgtcaaaat aagcgcctag gatattgcca gaagcatcat caatggctag
    13141 gtgtaagtta gaggtttctg ctccaaacca ggcatgaggg ctggcatcca tttggatgag
    13201 ttctccagca aatttctttc tgggtctact aggatgtacc tttttagggt cttccaggaa
    13261 gttttcagcc gtcggtaaga ttggattgtc taggggttgc ttggggttca gtttagcttg
    13321 ctttcttact ctcttctttg tctttctatg ggacttaggc gacaggatat ttttcttata
    13381 gagtattttt ctaacagttg tatcagagag ctgaattcct tcttcttcag ctagcaattc
    13441 acagaaatga cggacatttg gtttatatgt ttcataggag aggtatttct ttaggatacg
    13501 ttctttgatt tcatcaggga ttgcatgttt tggttttcga tttctgtttc cgtgtctgaa
    13561 ggcttctttt cctttctgtt gataggctag tagcagacga ttgatttgcc tttcagaaag
    13621 attgagctcg acacaggctc gtttctttgt tttctttcct tgggctatag cttttatcac
    13681 aagatatttt ttcgtttcat tcatattcag ttggatcctt tacatatgac tattctacca
    13741 aatgggacat ttttacgttc gatttactaa agacattatc acattcgaat tacacaagat
    13801 gcagatagtg aaaaaaaggt gtagacatta ccgtaaaaaa gtgatataat tgtaagatgt
    13861 tcaatgtata ggtgttaatc atgagtagac gttttaaaaa atcaggttca cagaaagtga
    13921 agcgaagtgt taatatagtt ttgttgacta tttatttatt gttagtttgt tttttattgt
    13981 tcttaatctt taagtacaat atccttgctt ttagatattt taatctagtg gtaactgcgt
    14041 tagtcctact agttgccttg gtagggctac tcttgattat ccataaaaaa gctgcaaagt
    14101 ttactatttt tctgttggtg ctctctattc ttgtcagctc tgtgtcgctc tttgcagtac
    14161 agcagtttgt gggactgacc aatcgtttaa atgcgacttc taattactca gaatattcga
    14221 tcagtgtcgc tgttttagca gatagtgaga ttgagaatgt tacgcaactg acgagtgtga
    14281 cagcaccgac tgggactgat aatgaaaaca ttcaaaaact actagctgat atcaaatcaa
    14341 gtcagaatat cgatttgacg gtcaatcaaa gttcgtctta cttggcaact tacaagagtt
    14401 tgattgcagg agagactaag gccattgtct taaatagtgt ctttgaaaat atcatcgaat
    14461 cggagtatcc agattacgca tcgaagataa aaaagattta taccaaggga ttcactaaaa
    14521 aagtagaagc tcctaagacg tctaagaatc agtctttcaa tatctatgtt agtggaattg
    14581 atacttatgg tccgattagt tcggtgtcgc gttcagatgt caatatcctg atgactgtca
    14641 atcgagatac caagaaaatt ctcttgacca caacgccacg tgatgcttat gtaccaatcg
    14701 cagatggtgg gaataatcaa aaagataaat tgacccatgc gggcatctat ggagttgatt
    14761 cgtccattca caccttagaa aatctctatg gagtggatat ccattactat gtccgtttga
    14821 acttcacttc tttcttgaaa ttgatcgatt tgttgggtgg ggtagatgtt tataatgacc
    14881 aagatttcac atctctacac gggaagttcc atttcccagt tggaaatgtc cacttagatt
    14941 ctgagcaggc tctgggattt gttcgtgagc gctattccct agcggatggt gatcatgacc
    15001 gcgggcgcaa tcaacaaaag gtgattgcgg ctatccttca aaaattaact tcgagcgaag
    15061 cgctgaaaaa ttatagtatg atcattgata gcttgcaaga ttctatccaa acaaacatgc
    15121 cccttgagac catgataaac ttggtcaatg ctcagttaga aagtggtgga acgtacaaag
    15181 taaattcgca agacttgaag ggtaggggac ggacggatct tccttcctat gcgatgccag
    15241 atagtaacct ctatatgatg gaaattaacg acagtagcct tgcatctgtc aaaactgcta
    15301 ttcaggatgt gttggagggc agatgaaatg attgatattc attcgcacat tgtctttgat
    15361 gtagatgatg gtcccaagtc aagagaggaa agtaaggctc tcttgacaga agcctacagg
    15421 cagggggtgc gaaccattgt ctctacctct caccgtcgca agggcatgtt tgaaactcca
    15481 gaagagaaga tagcagaaaa ctttcttcag gttcgggaaa tagctaagga agtcgcgagt
    15541 gacttggtca ttgcttatgg ggccgaaatt tactacacac cagatgtttt gggtaagctg
    15601 gaaaaaaatc ggattccgac cctcaataat agtcgttatg ccttgataga gtttagtatg
    15661 aacacccctt atcgcgatat tcatagtgcc ttgattaaaa tattgatgtt gggaattact
    15721 ccagtcattg cccacatcga gcgctatgat gctcttgaaa ataatgaaaa acgcgttcga
    15781 gagctgatta atatgggctg ttacacgcaa gtaaatagtt cacatgtcct caaatccaaa
    15841 ctttttggag aaccttataa attcatgaaa aaaagagctc agtatttctt ggagcgtgat
    15901 ttggttcatg tgattgcaag tgatatgcat aatgtggaca gcagacctcc ccatatggca
    15961 gaagcatatg accttgtttc ccaaaaatac ggagaaacga aggctcagga cctttttata
    16021 gacaatcctc gaaaaattgt aatggatcaa ctaatttagg agaaataatg aaagaacaaa
    16081 acacgataga aatcgatgta tttcaattac ttaaaacctt gtggaaaaac aagctaatca
    16141 ttttattagt ggcacttgtg acaggggcgg gagcttttgc atatagcatt tttattgtta
    16201 agccagaata tacaagcacc acgcgtattt acgtagtcaa tcgtaatcaa gaaaataagc
    16261 cgggactgac gaatcaggac ttgcaggcag gaacttatct ggtaaaagac taccacgaaa
    16321 ttatcctttc gcaagatgta ttggaaaagg tagcgacaaa tttgaaattg gatattccag
    16381 taaaaacgtt aactagcaaa gtgcaagtga ctgtaccagc cgacactcgt atcgtctcaa
    16441 tctctgtcaa ggataaacaa ccagaggaag ccagtcgcat tgctaattct atacgagaag
    16501 ttgctgcaga aaagatcatc gctgtaacgc gagtatctga tgtaacgacg cttgaagaag
    16561 cgcgaccagc tacgactccc tcttctccaa atgttcgacg caacacctta gttggttttc
    16621 ttggagccgc cgccgtaaca gtaattactg ttcttttgat tgagttgttc gatacccgtg
    16681 taaaacgtcc tgaagaagtt gaagatgtac tgcaaatgcc acttctagga gtcgttccag
    16741 attttaataa aatgaaatag gaggaagtta tgccaacgtt agaaatctca caggcgaaat
    16801 tagaacttgc gaaaaagaca gaggaatatt ataatgcttt gtgcacgaac ctacagttaa
    16861 gtggagatga tttgaaagta ttttctatca gttctgtgaa agcaggagaa ggaaaaacaa
    16921 cgacttccac caatatcgct tgggcttttg cgcatgcagg ttacaaaacg ctgctgattg
    16981 atgcagacat gcgtaactcc gttatgtcag gtgtctttaa atcaagggaa aggattactg
    17041 ggctaacaga atttctatca gggacaacag acctgtcaca ggggctttgc gataccaatg
    17101 ttgagaatct ctttgtgatt caggctggct ctgtgtcacc aaatccgata gcccttcttc
    17161 aaagtaagaa tttcagtaca atgcttggaa ccttgcgtaa atattttgac tatatcgtcg
    17221 tagacactgc tcctatcggt atcgtgattg atgcggctat cattatgcag aaatgtgatg
    17281 cttctatttt agtgacgaag gcaggtgaaa caaaacgacg ggaacttcaa aaagcgaaag
    17341 aacagttgga acaaactggg aagtcgtgtt taggagttgt gttgaataaa ttcgatactt
    17401 cagtagacaa atacggtttt tatgggagtt atgggagtta caggaaacag aaaaaatagg
    17461 ttgagggata gagatgaatg aaaaactagc aaagtcttca gtagctatag tccagagttt
    17521 tcttgttatt ttattgactt atctacttag cgctgtgaga gaaacagaga ttgtttcaac
    17581 aacagctatt gtactttata tcctccacta ttttgtcttt tatatcagtg attatggacg
    17641 gaatttcttt aaaaggagat atttgattga acttgtccag acattgaaat atatcctatt
    17701 ctttgcgcta gcgattagta tttctaattt tttcttagag gatcgattta gtatttccag
    17761 acgaggcatg atttacttcc tcctattaca tgttttctta gtctatatgc taaacctatt
    17821 tatcaagtgg tattggaagc gggcttatcc caactttaaa ggaagtaaga aggttttcct
    17881 acttacagca acttctcatg tcgaaaaggt actggataga ctaatagaat cagatgatgt
    17941 tgttggggag ttggtagccg tcagtgtttt agataaacca gattttcagc atgatgattt
    18001 aaaggttgta gcagaggggg agatcgtaaa ctttgcgact cgtgaggtgg tcgatgaagt
    18061 ctttatcaat cttccaagtg aaaaatacaa tattggagag cttgtctctc agtttgaaac
    18121 gatgggaatt gatgtaacag tcaatctaaa tgctttcgat tgggcacgta acaagcaaat
    18181 ttgtgagatg gcaggactaa atgttgtgac tttttctaca acattttata agactagcca
    18241 tgtgattgct aagcgggtta ttgatattat cggttccctg gtaggtttga tactatgtgg
    18301 tctagtcagt attgtgctgg ttcctttgat tcgaaaggat gggggctctg ctatttttgc
    18361 tcagacgcgt ataggaaaaa atggccgcca tttcactttt tacaagtttc gctctatgtg
    18421 tgtagatgct gaggataaaa agagagaact catggaacaa aataccatgc agggtggaat
    18481 gtttaaggtg gacgatgatc ctcgtatcac gaaaattggt cattttatac ggaagacgag
    18541 cttggacgag ctaccacagt tttataatgt tctaaaggga gatatgagtt tggtaggtac
    18601 acgaccacca acagtggacg agtatgaaca ctatacccca gaacaaaaac gtcggctaag
    18661 ttttaaacct ggtataacag gcttatggca ggtcagtgga cgaagtgaaa tcaaaaattt
    18721 cgatgaagtt gtcaaattag atgtggtcta tattgatggt tggacaatct ggaaagatat
    18781 tgaaatttta ttgaagacag ttaaagttgt attgatgaag gatggagcga aatagtttgc
    18841 ttttgtttca gactattagg agaaaaatga agaagtcagt ttatatcatt ggttcaaaag
    18901 ggattcccgc taagtatggg ggctttgaaa cctttgttga gaaattaaca gaatatcaaa
    18961 aagatggtaa catccaatac tatgttgcct gcatgcgcga aaattctgca aaatcaggat
    19021 ttacagcaga tacatttgag tacaatgatg ctatttgtta caacattgat gtgcctaata
    19081 ttggtcctgc tagagccatt gcttatgata ttgctgctgt gaataaagcg attgaaatag
    19141 ctaagaaaaa caaagatgaa gctcctattt tttacattct agcttgtcgt atcgggcctt
    19201 ttatagctag acttaagaaa aagattcaag ctatcggagg tactctgttt gtcaatccag
    19261 atggacatga gtggcttcgg gctaaatgga gcctgccggt tcgaaagtat tggaaatttt
    19321 cggaacagtt gatggtcaaa tatgcagatt tattggtctg tgatagcaaa aatattgaaa
    19381 aatatatcca gaatgactat aagcaatatc aaccaaagac gacttatatt gcttacggga
    19441 cggatacaag tccgtctatc ctgaaatccg aagatctaaa aattcgtagt tggtatcagg
    19501 aaaaaggact tagcgaaaat ggctattatc tagtggtggg acgattcgtc cctgaaaaca
    19561 actacgaaac catgattcgt gaatttatca aatctaagtc caagaaggac tttgtcctca
    19621 tcacaaatgt ggagcagaat aaattttacg accagttgtt acaggagact ggttttgaca
    19681 aagatcctag ggttaaattt gtaggtactg tctatgacca agaattgctt aagtacattc
    19741 gtgaaaatgc ttttgcctat ttccatgggc atgaggttgg agggaccaac ccttctctac
    19801 tagaagctct agcatccaca aaactgaatt tgttgctaga tgttggtttt aaccgtgagg
    19861 ttggtgaaga cggggctatt tattggagaa aagataatct tcataaggtt attgaagaga
    19921 gtgaacaaaa aacaatagaa gaaataaaag aaatagatat tctatctaca gagcaggtag
    19981 aaaaaagatt tacttgggat tttattgtta atgaatatga aaatttattt ttactaggga
    20041 aataattatc taagttacaa ggattttatt tgaggaagct ttgatggaag ttcatcactt
    20101 tcttagacaa ttatctaaat aacttatgtt attcatgaag tttttaaaat gatagatatt
    20161 ctcccttttt gcaaagatac taaaattata gagaggaaat atgcccagta gttgatagtg
    20221 tttttgggta gggttaaacg acatagtttt aagacaaact ggtggagatt taagaaataa
    20281 gtagttctta ttaaatcaaa aacgtgttct tattctatat tgtcatttag tcaaaggtat
    20341 caagtatgac tattaaaatt aattatatgt tttttgtttg tctctct
//
LOCUS       DAVLMQ010000033        18415 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000033 DAVLMQ010000000
VERSION     DAVLMQ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.033"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            826..2085
                     /locus_tag="VXF95_001462"
     CDS             826..2085
                     /locus_tag="VXF95_001462"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HEV1081996.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
     gene            2101..2652
                     /locus_tag="VXF95_001463"
     CDS             2101..2652
                     /locus_tag="VXF95_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1081997.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            2645..3922
                     /locus_tag="VXF95_001464"
     CDS             2645..3922
                     /locus_tag="VXF95_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1081998.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            3938..4798
                     /locus_tag="VXF95_001465"
     CDS             3938..4798
                     /locus_tag="VXF95_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HEV1081999.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            5177..5961
                     /locus_tag="VXF95_001466"
                     /pseudo
     CDS             5177..5961
                     /locus_tag="VXF95_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            6152..8443
                     /gene="pcrA"
                     /locus_tag="VXF95_001467"
     CDS             6152..8443
                     /gene="pcrA"
                     /locus_tag="VXF95_001467"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HEV1082000.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQDCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTTYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVVRT
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGLGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNTQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDPDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKPASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            8486..9166
                     /gene="radC"
                     /locus_tag="VXF95_001468"
     CDS             8486..9166
                     /gene="radC"
                     /locus_tag="VXF95_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HEV1082001.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(9163..9852)
                     /locus_tag="VXF95_001469"
     CDS             complement(9163..9852)
                     /locus_tag="VXF95_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HEV1082002.1"
                     /translation="MKKPVIGITGNEKAHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9870..10511)
                     /locus_tag="VXF95_001470"
     CDS             complement(9870..10511)
                     /locus_tag="VXF95_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HEV1082003.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            complement(10594..10809)
                     /locus_tag="VXF95_001471"
     CDS             complement(10594..10809)
                     /locus_tag="VXF95_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HEV1082004.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            complement(10817..11164)
                     /locus_tag="VXF95_001472"
     CDS             complement(10817..11164)
                     /locus_tag="VXF95_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HEV1082005.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKELTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            complement(11169..12284)
                     /locus_tag="VXF95_001473"
     CDS             complement(11169..12284)
                     /locus_tag="VXF95_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HEV1082006.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFANNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            complement(12294..13253)
                     /locus_tag="VXF95_001474"
     CDS             complement(12294..13253)
                     /locus_tag="VXF95_001474"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1082007.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            complement(13366..13935)
                     /locus_tag="VXF95_001475"
     CDS             complement(13366..13935)
                     /locus_tag="VXF95_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HEV1082008.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAENYLSKEELPQGLVLDEL
                     AKHGIQIKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDMTDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            14063..14734
                     /locus_tag="VXF95_001476"
     CDS             14063..14734
                     /locus_tag="VXF95_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HEV1082009.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            14718..15536
                     /locus_tag="VXF95_001477"
     CDS             14718..15536
                     /locus_tag="VXF95_001477"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HEV1082010.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLEKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIAHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            15533..16429
                     /locus_tag="VXF95_001478"
     CDS             15533..16429
                     /locus_tag="VXF95_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1082011.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIDIPAEKGFETLEAIELPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            16473..17447
                     /gene="pta"
                     /locus_tag="VXF95_001479"
     CDS             16473..17447
                     /gene="pta"
                     /locus_tag="VXF95_001479"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HEV1082012.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(17847..18146)
                     /locus_tag="VXF95_001480"
     CDS             complement(17847..18146)
                     /locus_tag="VXF95_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HEV1082013.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
BASE COUNT         5446 a         3350 c         4013 g         5606 t
ORIGIN      
        1 aactatattg ttataaattg atttgaattt caaaattaaa ttgtttgatt cttatttcaa
       61 tttgttatag tatatctgat gtcaaagttc tcggcgagtc aaatagcgat tcccaagcct
      121 gactatcgtg aggtagcgga ttaaaatggt ctggggatag accgttttaa gtctgacgct
      181 ggaaataaga attgtcagaa gaagggatag agaaatcgtg gctctacgaa caggaacgtg
      241 ataataaggc gtatatagcg gataagaggg cctcaaactc taaagtccaa aaaggtagtc
      301 gtaacctaat aaagagaaaa cgacagatag aagtgatcct gagtcacggt tatctttaaa
      361 atagattgtc tgataggacg gtatgtataa aacgcttctg tgaattgaga gaaggggaga
      421 agttcttgct aaaatttagt tgaacagccg tattccgata cttagataag agatctagtc
      481 ttagccccta ctcagtttta ggggataaaa aaggggcaat agcgattcga gaaagattat
      541 actcttcgaa aatctcttca aatcacgtca atatcgcctt gccgtatgtg taggatactg
      601 actacgtcag ttccatctac aacctcaaaa cagtgttttg agcaacctgc ggttagtttc
      661 ctagtttgat ctttgatttt cattgagtat tagtaattca gttactaact cgtcaactct
      721 gatttatcca ataaaattga aaaggatgga aaaaaggata aatttatgat atactttatt
      781 ttgaagacct tattagaaat cttgaaagag tattgaaaac ttagaatgag aaaaattgtt
      841 atcaatggtg gattaccact gcaaggtgaa atcactatta gtggtgctaa aaatagtgtc
      901 gttgccttaa ttccagctat tatcttggct gatgatgtgg tgactttgga ttgcgttcca
      961 gatatttcgg atgtagccag tcttgtcgaa atcatggaat tgatgggagc tactgttaag
     1021 cgttatgacg atgtattgga gattgaccca agaggtgttc aaaatattcc aatgccttat
     1081 ggtaaaatta acagtcttcg tgcatcttac tatttttatg ggagcctctt aggccgtttt
     1141 ggtgaagcga cagttggtct accgggagga tgtgatcttg gtcctcgtcc gattgactta
     1201 caccttaagg cgtttgaagc tatgggtgcc actgctagct acgagggaga taacatgaag
     1261 ttatctgcta aagatacagg acttcatggt gcaagtattt acatggatac ggttagtgtg
     1321 ggagcaacga ttaatacgat gattgctgcg gttaaagcaa atggtcgtac tattattgaa
     1381 aatgcagccc gtgaacctga gattattgat gtagctactc tcttgaataa tatgggtgcc
     1441 catatccgtg gggcaggaac taatatcatc attattgatg gtgttgaaag attacatggg
     1501 acacgtcatc aggtgattcc agaccgcatt gaagctggaa catatatatc tttagctgct
     1561 gcagttggta aaggaattcg tataaataat gttctttacg aacacctgga agggtttatt
     1621 gctaagttgg aagaaatggg agtgagaatg actgtatctg aagacagcat ttttgtcgag
     1681 gaacagtcta atttgaaagc aatcaatatt aagacagctc cttacccagg ctttgcaact
     1741 gatttgcaac aaccgcttac ccctctttta ctaagagcga atggtcgtgg tacaattgtc
     1801 gatacgattt acgaaaaacg tgtaaatcat gtttttgaac tagcaaagat ggatgcggat
     1861 atttcgacaa caaatggtca tattttgtac acgggtggac gtgatttacg tggggccagt
     1921 gttaaagcga ccgacttaag agctggggct gcactagtca ttgctgggct tatggctgaa
     1981 ggtaaaactg aaattaccaa tatcgagttt atcttacgtg gttattctga tattatcgaa
     2041 aaattacgta atttaggagc ggatattaga cttgttgagg attaaaccgt agaggtgttt
     2101 atgaatattt ggaccaaatt agcaatgttt tctttttttg aaacggatcg cttgtatttg
     2161 cgtcctttct tttttagtga tagtcaggac ttccgcgaga tagcttcaaa tccagaaaat
     2221 cttcaattta ttttcccaac gcaggcaagt ctggaagaaa gtcaatatgc actggccaat
     2281 tactttatga agtccccttt gggagtgtgg gcaatttgtg accagaaaaa tcaacaaatg
     2341 attggttcta ttaaatttga gaagttagat gaaatcaaaa aagaagctga gcttggctat
     2401 tttttgagaa aagatgcttg gtcgcaagga tttatgacag aggttgttag aaaaatttgt
     2461 cagctttctt ttgaggaatt tggcttaaaa caattatcta tcattaccca ccttgaaaat
     2521 gaagctagcc aaagagttgc tcttaagtct ggatttagtt tgttccgtca gtttaaggga
     2581 agtgatcgtt acacaagaaa aatgcgggat tatcttgaat ttcggtatgt aaaaggagag
     2641 ttcaatgagt aagcatcagg aaattctaag ctatttggag gaattaccag taggtaaaag
     2701 ggtcagtgtt cgtagcattt cgaatcatct aggagttagt gatggaacag cctatcgggc
     2761 tattaaagaa gctgaaaacc gtggaattgt ggagacccgt cctagaagtg gaacaattcg
     2821 tgttaaatcc cagaaagttg ctatagagag attaacgttt gctgaaattg cagaagtgac
     2881 ttcttctgag gttctggctg ggcaagaagg tttagagaga gaatttagta agttttcaat
     2941 tggtgccatg actgaacaaa atatcttgtc ttaccttcat gatggggggc tcttgattgt
     3001 cggagaccga acccgtattc agttgctagc cttggaaaat gaaaatgcag ttctggttac
     3061 agggggattt caggttcatg atgatgtgct taaactggcc aatcaaaaag ggattcctgt
     3121 tctaagaagt aagcatgata cctttaccgt cgcgaccatg atcaataaag ccttgtcaaa
     3181 tgtccaaatc aagactgata ttctgacagt tgagaaactt tatcgcccta gtcatgagta
     3241 tggttttctg agagagacag atacagttaa agattatttg gacttggttc gtaagaatcg
     3301 tagcagccgt ttccctgtta tcaatcaaca tcaggtcgtt gttggcgttg taaccatgag
     3361 agacgctggt gataaatcac caagcacgac aattgataag gttatgtctc gtagtctatt
     3421 tttggttgga ttatcgacaa atattgccaa tgtgagtcaa cggatgatcg cagaagactt
     3481 tgaaatggta ccagttgttc gaagcaatca aactttgctt ggcgttgtga cgcgacgaga
     3541 tgtcatggag aagatgagcc gttctcaagt ttcggctcta ccaacttttt ctgagcagat
     3601 tggacaaaag ctctcttatc accatgatga agtagtcatt acagtggaac cctttatgct
     3661 agaaaaaaat ggagttttgg ctaatggtgt attggcagaa attctgaccc acatgaccca
     3721 agatttagtt gttaatagtg gtcgcaatct cattatcgag cagatgctaa tctacttttt
     3781 gcaggctgtt cagatagatg atatattgcg cattcaggca cggattattc atcatacgag
     3841 acggtcagct ataattgatt acgatattta tcatggtcac cagattgttt caaaagcaaa
     3901 tgtgactgtt aaaattaatt agaaactagg agaaaagatg ataacattaa aatcagctcg
     3961 tgaaatcgaa gctatggaca aggctggtga ttttctagca agtattcata taggcttacg
     4021 tgatttgatt aagccaggcg tagatatgtg ggaagttgaa gaatatgtcc gccgtcgttg
     4081 taaagaagaa aatttccttc cacttcagat tggggttgac ggtgccatga tggactatcc
     4141 ttatgctacc tgttgctctc ttaacgatga agtggctcac gctttccctc gtcattatat
     4201 cttgaaagat ggtgatttgc tcaaagttga tatggttttg ggaggtccca ttgctaaatc
     4261 tgacctgaat gtctcaaaat taaacttcaa caatgttgaa caaatgaaaa aatacactca
     4321 gagctattct ggtggtttag cagactcatg ttgggcttat gctgttggta caccgtccga
     4381 agaagtcaaa aacttgatgg atgtaaccaa agaagctatg tacaagggta ttgagcaagc
     4441 tgttgttgga aatcgtatcg gtgatatcgg tgcggctatt caagaatacg ctgaaagtcg
     4501 tggttacggt gtagtgcgtg atttggttgg tcatggtgtt ggcccaacta tgcacgaaga
     4561 accaatggtt cctaactatg gtattgcagg tcgtggactc cgtcttcgtg aaggaatggt
     4621 cttaaccatt gaaccaatga tcaatacagg cgattgggaa attgatacag atatgaaaac
     4681 tggttgggcg cataagacca ttgacggtgg attgtcatgt cagtatgaac accaatttgt
     4741 cattacgaaa gatggacctg ttatcttgac tagccaaggt gaagaaggaa cttattaata
     4801 aaaagtgaaa agactactgg aagtttatta tgaaaaaatc cagtagatct tttcataata
     4861 aaacgcattg tatcaagtgt taggggctga tatcatgcgt ttttctgctt ttaagatttt
     4921 ttccaactct gtttgtaagc gcatcataac aaagggtcta ggattcaggg ctctcctcct
     4981 atatactatt agtaaagtaa aactaaggga ggatatttta gtgtcgcagt ctattgttcc
     5041 tgtagagatt ccacaatatt gtcgttttga ttctaaaaag agaaatggaa ttctgtttaa
     5101 tgttcgtatt gccaatctta aatttacctt ttttagatta gacttcctgc gaaacaaaat
     5161 atggtatagt agttctatga atgatgaagc aagtaaacaa ctaactgatg cacgatttaa
     5221 gcgtcttgtt ggtgttcagc gtaccacttt tgaagagatg ttagctgtat taaaacagct
     5281 tatcaactta aacacgcaaa aggtggacga aaacctaaat taagcctgga agaccttctt
     5341 atggccactc ttcaatatgt gcgagaatat cgcacttatg aacaaattgc ggctgatttt
     5401 ggtattcacg aaagcaactt actccgtcgg agccaatggg ttgaagtaac tcttgttcaa
     5461 agcggtttta cgatttcaag agctcctctc agttctgagg acacggtaat gattgatgcg
     5521 acggaagtac aaatcaatcg ccctaaaaaa acaattagcg aatgattctg gtaaaaagaa
     5581 atttcatgct atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctattgt
     5641 catgatatga agttgttcaa aatgagtcgc ggaaatatcg gacaagctgg taaaatcttg
     5701 gctgacagtg gttatcaagg gctcatgaag atatatcctc aagcacaaac tccacgtaaa
     5761 tccagcaaac tcaagtcgct aatagctgaa gataaagcct ataaccatgc gctatctaag
     5821 gagagaagca tggttgagaa catctttgcc aaagtagaaa cgtttaaaat gttttcaaca
     5881 acctatcgaa atcatcgtaa atgcttcgga ttacgaatga atttgattgc tggtattatc
     5941 aatcatgaac taggattcta gttttgcagg aagtctattg aggtattgag ctagtttatg
     6001 aaaaaattga gtgaaaagtc gagtgtttta gaaacccaca gtgtagtatt ctagtttcaa
     6061 tccactatat tttgctactc cccgtaaagt ttctattttc cctgatttct gatataatag
     6121 aaatattgac ttcaagagta aggaagagaa gatgaacgca ttattaaatg gaatgaatga
     6181 ccgtcaggct gaggcggtgc aaacgacaga aggtcccttg ctaatcatgg caggggctgg
     6241 ttctggaaag actcgtgttt taacccaccg tatcgcttat ttgattgatg aaaagctggt
     6301 caatccttgg aatatcttgg ccattacctt taccaacaag gctgcgcgtg agatgaaaga
     6361 gcgtgcttat agcctcaatc cagctactca ggactgtctg attgcgacct tccactccat
     6421 gtgtgtgcgt attttgcgtc gcgatgcgga ccatattggc tacaatcgta attttacaat
     6481 tgtggatcct ggtgaacagc gaacgctcat gaaacgtatt ctcaaacagt tgaacttgga
     6541 tcctaaaaaa tggaatgaac gaactatttt ggggaccatt tccaatgcta agaatgattt
     6601 gattgatgat gttgcttatg ctgcccaagc tggcgatatg tatacgcaaa ttgtggccca
     6661 gtgttataca acctatcaaa aagaacttcg tcagtctgaa tccgttgact ttgatgattt
     6721 gattatgctg accttgcgtc tctttgatca aaatcctgat gttttgacct actaccagca
     6781 aaaattccaa tacatccacg ttgatgagta ccaagatacc aaccacgctc agtaccaatt
     6841 ggtcaaactc ttggcttccc gttttaaaaa tatctgtgtg gttggggatg cggaccagtc
     6901 tatctacggt tggcgtggtg ctgatatgca gaatatcttg gactttgaaa aggattaccc
     6961 caaagccaag gttgttttgt tggaggaaaa ttaccgctca accaaaacca ttctccaagc
     7021 ggccaacgag gttattaaaa ataataaaaa tcgccgtcct aaaaatctct ggactcaaaa
     7081 cgctgatggg gagcaaatcg tttactatcg tgccgatgat gagctggatg aggctgtatt
     7141 tgtagtcaga accatcgatg aacttagtcg cagtcaaaac ttccttcata aggattttgc
     7201 agttctctat cggactaatg cccagtcccg tacaattgag gaagccctgc tcaagtctaa
     7261 cattccttat accatggttg gtggaaccaa attctacagc cgtaaggaaa ttcgcgatat
     7321 tattgcttat ctcaacctta ttgctaattt gagtgacaat attagttttg agcgtattat
     7381 caacgagcct aaacgtggaa ttggtctagg tacagttgag aaaatccgtg attttgcaaa
     7441 tttgcaaaat atgtctatgc tggatgcttc tgctaatatt atgttgtctg gtatcaaggg
     7501 taaggcagcc caatctatct gggattttgc caatatgatg cttgatttgc gggagcagct
     7561 agaccactta agcattacag agttggttga gtccgtccta gaaaaaacag gttatgtcga
     7621 tattcttaac acccaagcga ctctagaaag caaggcaagg gttgaaaata tcgaagagtt
     7681 tctttctgtt acgaagaact ttgatgacac cactgatgtg acagaagagg aaactggtct
     7741 ggacaaactg agtcgtttct taaatgactt ggctttgatt gccgacacag attcaggtag
     7801 tcaggaaaca tcagaagtga ccttgatgac cctgcatgct gccaaaggtc tcgaatttcc
     7861 agttgtcttt ttgattggga tggaagaaaa tgtctttcca cttagtcgtg cgactgaaga
     7921 tccagatgaa ttagaagaag agcgccgtct agcctatgta ggtatcacgc gtgcagagaa
     7981 aattctctat ctgaccaatg ccaactcacg cttgcttttt ggtcgtacca attataaccg
     8041 tccgactcgt tttattaacg aaatcagttc agacttgctt gagtatcaag gtctggctcg
     8101 tcctgcaaat acaagcttta aggcatcata tagcagtggt agtatttcct ttggtcaagg
     8161 tatgagtttg gctcaggctc ttcaagaccg taaacgcggt gctgccccaa aatcaatcca
     8221 gtcaagcggt cttccatttg gtcaatttac agctggcgca aaaccagcat ctagcgaggc
     8281 aaattggtcc attggtgaca ttgctctcca caagaaatgg ggagagggaa ctgttctgga
     8341 agtttcaggt agcggtgcta ggcaggaatt gaaaatcaat ttcccagaag taggtttgaa
     8401 aaaactttta gccagtgtgg ctccaattga gaaaaaaatc taattttcca tccttctcac
     8461 gaataataaa gtgaggagga tttttatgta cagtatttca ttccaagaag attcactatt
     8521 accaagagaa aggctggcca aggaaggagt tgaagcgctt agtaaccaag agttgctagc
     8581 tattttactc aggacaggaa cacgtcaagc tagcgttttt gaaattgccc aaaaagtctt
     8641 gaacaatctt tcaagcctaa cggatttgaa aaaaatgacc ctgcaggaat tgcagagttt
     8701 gtctggtatt gggcgtgtta aggccataga attacaagct atgattgaac tggggcatcg
     8761 tattcacaaa cacgagactc ttgaaatgga aagtattctc agcagtcaaa agttggccaa
     8821 gaagatgcag caggaattag gggataaaaa acaagagcac ctggtggcac tctatctcaa
     8881 tactcaaaat caaatcatcc atcagcagac catttttatc ggttctgtaa ctcgtagtat
     8941 cgctgaaccg cgagagattc ttcactatgc aatcaagcat atggcgactt ctcttatctt
     9001 ggtccacaat catccttcag gagcggtagc gcctagccaa aatgatgatc atgtcactaa
     9061 acttgttaaa gaagcctgcg aactgatggg gattgttctc ttggaccatt tgattgtctc
     9121 tcattctaat tactttagtt atcgtgaaaa gacagattta atctaaagtt cattaacgac
     9181 atagtcaaag agttttttat ctttgggacg attttcaaaa agaagttctg gatgccattg
     9241 gacaccgaga aaggcgacat catccgtact catgacagcc tcaatgatac catctttagg
     9301 atcatgagcc acaactttta aatttggtgc taagtccttg atgctctggt ggtggaagga
     9361 gttgatatga gagatttctc catagatttc ttggagaacg gtatctggtt ctgttaccaa
     9421 gcgttgagtt gtgtactcaa cagaagaatc ctgccaatgg tcttcgatat cttggtacaa
     9481 agttccaccc atggcaacgt taaagagttg ggtaccacgg cagacagaga aaatgggctt
     9541 tttctgttta atagcttcct tgatgagggc cagttcgaag atatctcttt gaaggtgata
     9601 gtcatcgcta tcaatggttt tgggttcgcc atagaatttt ggatcgacat tttgcccacc
     9661 tgtcaagatg agcttgtcaa tcaaactgat atagtggcag gccatttctt gatcaccaat
     9721 cggtaggatg atgggaatcc ctccagcatc tttaacgcct tcaacaaagc cttttgctgc
     9781 gtagctcatc atgatgtcat catctggatg agctttttcg tttcctgtaa tcccaataac
     9841 tggttttttc ataaaatgat tttcgctttc taatcctctt ttcgcatgaa gtagaggagg
     9901 gtttggagtt cacttgtcaa atcgacatac tgaacgacca cgtcttttgg taaatgcaga
     9961 tggactggtg aaaaactgag aattcctttc acaccagcat caaccaagag attagcaacc
    10021 tcttgtgact tgacgctggg aacagttagg atagcagtct tcacatcagc atccttgatt
    10081 ttatccttga tctgagaaat cccgtaaatg ggaatcccgt caggagtttg ggtaccgact
    10141 tcaggatggt cgtctaggtc aaaggccatg ataatcttca tcttgttacg ttcgtggaag
    10201 cggtagtgga gaagggcatg gcccatattt ccaataccaa ccagcatgac attggtaata
    10261 gagttgtcat tgagcaaatc ggcaaaaaat gtcattagtt ttttgacatc atagccaaaa
    10321 ccacgacgac caagttcacc aaaataggaa aaatcacgac gtacggtcgc tgaatcaata
    10381 ccgatagcct ctgcaatttg cttagagttg gcacgttcaa tcttttctgc atgaaatctc
    10441 ttaaaaattc gatagtagag agagagtctt tttgctgtag cttttggaat agcaaactgt
    10501 ttatctttca caaaatcaca acctttctat tcttctattt tatagaaaca ttgtgaaaaa
    10561 atcaacaaaa ataagaaaaa actaagaaaa atcttagttt tgatgtaaaa aatctgcatg
    10621 agatagaaaa cggtagaggt ctccgaccag accctgataa actttttggc ccctaaaagt
    10681 cagagaagtc acataaagtg tatctggtaa ggttacacat cctgacaaag tcaacatgag
    10741 agcctcatga tcctcatact tgagagtacg ctctacatga tagcagtcct tataggtcag
    10801 ttcaaacatt ttggctctat ctttccgatt ttgtaaagac accacgttct accaagctat
    10861 ccatgaggaa gtagaatttt tcctgatgaa tatggtggtc ttctgatttg aaaatatcaa
    10921 ctagacgaag gccaaacttg tcagtgatat tgattttagc ccctgtaagt tccttgttaa
    10981 tgatgatttt gagttggaag ccttcaccgc tgtttggcac tttttccaaa aggcgagtca
    11041 gttcatagtt accaacctta gtttcaaaaa aggtgttatc tttgagggtg aattttttaa
    11101 cagaagggct aagagtgtaa tcgtaacgac aattttttaa ctgaatgatt ttttcaaatg
    11161 ccatatggct aacctccgat aatttctttt aaggtttttg cgagggtttg taggtcttca
    11221 acggtatttt gtggcgacaa actgatgcga agggattcct tcaagcgttc tgaatttgcg
    11281 ccatacatgg cttcaagaac atggctggat tggacaacgc ctgcagtaca ggctgagcca
    11341 gtagagattg aaattccagc taaatctagc cgaaggagta agaggtcatt tttctgacca
    11401 ggaaatccaa tattgagaac ataagggaga tgatgttttc ctctattcaa gtaatactga
    11461 atgccctcca gctctgccag aaaggcagtt tctagatttt gtacatgttg aaaatgttct
    11521 tcttgttttt ctaggtcttc ttttagggct gcaaccatgc ctacgatagc aggcagattt
    11581 tcagttcctg cacgtttttt ctgttcctgg tctccgccat gtagatagga atcaaagtcc
    11641 atgctagatg cgtagagaaa accgattccc ttaggaccat ggaatttgtg ggcagaagca
    11701 gtgagaaaat caatgcccaa ttcttctgaa tgaattggga ttttaccaat agcctgaact
    11761 gcatcaacat gataggcagc agggtgttgc ttgagtattt ggccaatttc agcgatgggc
    11821 agtaggtttc ctgtctcatt attggcaaac atggtagaaa ccaaaatcgt atcgtcacgt
    11881 aaagcctttt gaatttgctg ggctgtgatt tcttgatttt ctggctggat aatggttgct
    11941 tcaaacccaa agtgttgaac caagtaatca attgtttcaa ggacagcatg gtgctcgatg
    12001 gcagttgtga tgatatgttt tccttgttct tggtgacgaa gacagtagcc aatgatggta
    12061 gtattattgc cttcagtccc accagaagtg aaaaagatat gttgaggttt tgtccttagt
    12121 aactgggcta gttcctgacg ggcttctcgc aagagtttgc cagcttgacg accatgacca
    12181 tgaatactag aaggatttcc gtgggtttct tgcataacct tggtcatagc tgaaatagca
    12241 actgctgaca taggagtcgt tgcagcattg tccaaataaa tcaaagaatc accttatttc
    12301 tttttattgt aggcaaagag tgggctgact ggttttcttt cgtgaatacg gacgatagca
    12361 tcaccaatta actcactagc agtgatgtag catacatttt taggagtttt ttcttttgtt
    12421 gctactgaat cagtcacaag aatttcttta atattagtat tgtcaagaag ctcagcagct
    12481 ccctcgacga agagaccgtg gctagaaaca gcataaattt ctgtagctcc ttcacgttca
    12541 acgattttag aagcttcaga gaaggtacgt cctgtattta aaatatcatc aatcaagata
    12601 gctttcttac cttcaacatc accaataata taaccttcgt tacgagttgc atcgtcttga
    12661 gggtagtcga taatggcgat aggagcatca agatattcag ccaggctacg cgcacgtttg
    12721 acacctgaat ttttagggct aacgacaaca acatctgaac caagcaatcc tttatcgcag
    12781 taatgttttg cgaatagggg aacagtgaaa agattatcca ctggaatatc aaagaaacct
    12841 tgaacctgaa cggcatgcaa atcaagagtc aggatacgat caactccagc cttaaccagc
    12901 atattggcaa ctagttttgc tgtaagtggc tcacgaggac aagcaatgcg gtcttgacgt
    12961 gcatagccaa aatatggaag gacaacgttg atactgtggg cacttgcacg cacacaagca
    13021 tcgaccatga ttaacaattc cattaggtgg ttgttgacag ggaaacttgt tgattggatg
    13081 atgtaaacat cataaccacg gacactttct tcgatattta cttggatttc tccgtctgaa
    13141 aattgacgtg atgatagttt tccaagtggg acaccaacag cttgggcaat tttctgtgca
    13201 atctcttggt tagagttgag tgcgaaaagt ttcatgtttt ttctatctga cattatagac
    13261 cgtcctctgt aaactttata aatcctagtt atatttacct tacatatatg aactggagtt
    13321 tgtgtatttt tatcttttct attttaccaa aaaatggaga ttatttcagc tatttttcat
    13381 acttttgaca aatcgaacca attttgaagg agctttttgg taggaaatct gatttttctc
    13441 taaaaattgt cggaaatcct gtttgccttg ctcatgattt tccacttcaa gctccaattc
    13501 gtaatctgtc atatcaaagt atcggctctg atccagtgcc atgagaccaa tagctgtttt
    13561 catttcatag cgaagcgttg ttagacaacc aagaacctgc cagttcttaa tttggatacc
    13621 atgtttcgcc aattcatcca gtactagccc ttgaggaagt tcttccttac tcagatagtt
    13681 ctcagcatct tttagttgca atttttggtt gtattccatg tttccaacac tctgcgggac
    13741 tttgagtgtc aactcagccc agtcttcaaa ggttcgaatg cgcatagcga ctttcttttc
    13801 tcgcagttca aaatcaggcg tgtcgatgta gtaatttgtt tgaagaacag gagtgacacc
    13861 tgtgaactgg tcttttagac gattgtattc atcttttttc aatagtgttt tcaattcaat
    13921 ttctaaatgt ttcatttttc ttaccttttt ttatcgttga aagcggattt atggtataat
    13981 aagcattgta tttattgtat atgaatctgg agaaaaaatc aaagatattt ttgacggata
    14041 atatgagaac aagggagaat atatgacctt agaatgggaa gaatttctag atccttacat
    14101 tcaagctgtt ggtgagttaa agattaaact tcgtggtatt cgtaagcaat atcgtaagca
    14161 aaataagcat tctccaattg agtttgtgac cggtcgagtc aagccaattg agagcatcaa
    14221 agaaaaaatg gctcgtcgtg gcattactta tgcgaccttg gaacacgatt tgcaggatat
    14281 tgctggctta cgtgtgatgg ttcagtttgt agatgacgtc aaggaagtag tggatatttt
    14341 gcacaagcgt caggatatgc gaatcataca ggagcgagat tacattactc atagaaaagc
    14401 atcaggctat cgttcctatc atgtggtagt agaatatacg gttgatacca tcaatggagc
    14461 taagactatt ttggcagaaa ttcaaattcg tactttggcc atgaatttct gggcaacgat
    14521 agaacattct ctcaactaca agtaccaagg ggatttccca gatgagatta agaagcgact
    14581 ggaaattaca gctagaatcg cccatcagtt ggatgaagaa atgggtgaaa ttcgtgatga
    14641 tatccaagaa gcccaggcac tttttgatcc tttgagtaga aaattaaatg acggtgtagg
    14701 aaacagtgac gatacagatg aagaatacag gtaaacgaat tgatctgata gccaatagaa
    14761 aaccgcagag tcaaagggtt ttgtatgaat tgcgagatcg tttgaagaga aatcagttta
    14821 tactcaatga taccaatccg gatattgtca tttccattgg cggggatggt atgctcttgt
    14881 cggcctttca taagtacgaa aatcagcttg agaaggtccg ctttatcggt cttcacactg
    14941 gacatttggg cttctataca gattatcgtg attttgagtt ggacaagcta gtgactaatt
    15001 tgcagctaga tactggggca agggtttctt accctgttct gaatgtgaag gtctttcttg
    15061 aaaatggtga agttaagatt ttcagagcac tcaacgaagc cagcatccgc aggtctgatc
    15121 gaaccatggt ggcagatatt gtaataaatg gtgttccctt tgaacgtttt cgtggagacg
    15181 ggctaacagt ttcgacaccg actggtagta ctgcctataa caagtctctt ggcggtgctg
    15241 ttttacaccc taccattgaa gctttgcaat taacggaaat tgccagcctt aataatcgtg
    15301 tctatcgaac actgggctct tccattattg tgcctaagaa ggataagatt gaacttattc
    15361 caacaagaaa cgattatcat actatttcgg ttgacaatag cgtttattct ttccgtaata
    15421 ttgagcgtat tgagtatcaa atcgcccatc ataagattca ctttgtcgcg actcctagcc
    15481 ataccagttt ctggaaccgt gttaaggatg cctttatcgg tgaggtggat gaatgaggtt
    15541 tgaatttatc gcagatgaac atgtcaaggt taagaccttc ttaaaaaagc acgaggtttc
    15601 taagggattg ctggccaaga ttaagtttcg aggtggagct attctggtca ataatcaacc
    15661 gcaaaatgca acgtatctat tggacgttgg agactacgtt accattgaca ttcccgctga
    15721 gaaaggcttt gaaaccttgg aggctattga gcttccatta gatattctct atgaggatga
    15781 ccactttcta gtcttgaata aaccctatgg agtggcttct attcctagtg ttaatcactc
    15841 taataccatt gccaatttta tcaagggtta ctatgtcaag caaaattatg aaaatcagca
    15901 ggttcacatt gttaccagac tagataggga cacttctggc ttgatgctct ttgccaagca
    15961 cggttatgcc catgcacgat tagacaagca gttgcagaag aaatctatcg agaaacgcta
    16021 ctttgctttg gttaagggag atggacattt ggagccagaa ggggaaatta ttgctccgat
    16081 tgcgcgtgat gaagattcca ttattaccag acgagtggct aaaggcggaa agtatgccca
    16141 tacttcatac aagattgtag cttcttatgg aaatattcac ttggtctata ttcacctgca
    16201 cactggtcga acccatcaaa tccgagtcca tttttctcat atcggttttc ctttgctggg
    16261 agatgatttg tatggtggta gtctggaaga tggtattcaa cgtcaggctc tgcattgcca
    16321 ttacctatcc ttttatcatc catttttaga gcaagacttg cagttagaaa gtcccttgcc
    16381 ggatgatttc agtaacctta ttacccagtt atcaactaat actctataaa aactgtctca
    16441 gagtataatt attatcttaa aggagaaaac tcatggaagt ttttgaaagt ctcaaagcca
    16501 accttgttgg taaaaatgct cgtatcgttc tccctgaagg ggaagagcca cgtattcttc
    16561 aagcgactaa acgtttggta aaagaaacag aagtgattcc tgttttgtta ggaaatcctg
    16621 aaaaaattaa aatttatctt gaaattgaag ggatcatgga tggttatgag gtcatcgacc
    16681 ctcaacatta tcctcaattt gaagaaatgg tttctgcctt ggtggagcgt cgcaagggca
    16741 aaatgactga agaagatgta cgcaaggttt tggttgaaga tgtcaactac tttggtgtga
    16801 tgttggttta cttgggcttg gttgatggaa tggtgtcagg agcgattcac tcaacagctt
    16861 caacagttcg tccagctcta caaatcatca aaactcgtcc aaatgtaact cgtacttcag
    16921 gagccttcct catggttcgt ggtacggaac gttacctatt tggagactgt gccattaaca
    16981 tcaatccaga tgcagaagcc ttggctgaaa ttgccatcaa ctcagcaatc acagctaaga
    17041 tgtttggcat cgaacctaaa attgccatgt tgagctattc tactaaaggt tcagggtttg
    17101 gtgaaagcgt tgataaggtc gttgaagcaa ctaaaattgc tcacgacttg cgtcctgacc
    17161 ttgaaatcga tggtgagttg caatttgatg cagcctttgt tcctgaaact gcagctctga
    17221 aagctcctgg aagtacggta gctggtcaag caaatgtctt catcttccca ggtatcgagg
    17281 caggaaatat cggttacaag atggctgaac gcctgggtgg ctttgcggct gtaggacctg
    17341 ttttgcaagg tttaaacaag ccagttaatg atctttctcg tggatgtaat gcagatgatg
    17401 tttacaagtt gaccctcatc acagcagctc aagcagttca tcaatagtga aaactataaa
    17461 gcgatatact atgctatact gtagttatga aactatgtac gaaaagcact gccattaatt
    17521 cctgagaact aaattactga ttggtgtcaa aaaggaaaac ttccaagcga tgatatcctg
    17581 tctatacacg acctatagaa atctgtaata tgtatgtccg taaaacgata atttcccttt
    17641 ttgattttaa atgagtatga aaagagaatt ttttcatgag aaaacgcata atattaagtg
    17701 tcttgacacc tgctattatg cgttttctac aataaaatag gctccataat atctatagtg
    17761 gatttaccca ctacaaatat tatagagtca tttttgcacc tttcttagcc tttgttatcg
    17821 acaagcattg ttctagctcc ttgtttttag aaaggtaatt tcccagcgaa agcacccagt
    17881 tttttcttgg tagtttcatc gatttgttca agagcagagt tgatggcttg aacggtcata
    17941 tcagaaagag tctcaaggtc ctctgggtca acgacagctg gattgaaatc aatgctgaca
    18001 actttcttat cgccagttaa ggtcgcttgg acaagatctt gagcagattt gccaacaaat
    18061 tgcatagcag caagttcagc ttggctttgt tccatttgtt tttgaagttt ttgtgcttga
    18121 cgcatcatgt tttgcatgtt catcataaga tttctaaagt tcctttcatc tcaaggggat
    18181 aatccttgtt gttaacaagt gcctgatttt ctctcctaat tgttattagt agcatagcca
    18241 tcaagcccaa gtattgattt tattatacca tttttttaag acatagtctt ttattggtga
    18301 gagttattta tgtcaaggag tgattagaaa taaattaaaa taatgatttt tgctaagagg
    18361 ggctctattc tagtttcatg gaaatgattt tactaaagat tcgtatgctt tgttt
//
LOCUS       DAVLMQ010000034        18256 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000034 DAVLMQ010000000
VERSION     DAVLMQ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18256
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.034"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            68..5371
                     /locus_tag="VXF95_001481"
     CDS             68..5371
                     /locus_tag="VXF95_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1082014.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPTDLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWQTVEKKEQQGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKEDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPVVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYSLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPRAKVVITEDANADKKVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTDKEKMYYFNTQAGATTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKASVTVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRNNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGKGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDLYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGKMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIEALKNALVQKKTALVAED
                     FESLDAPAQPGEGLENAFDGNVSSLWHTSWGGGDVGKPATMVLKEATEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALAKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASDQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(5537..7696)
                     /locus_tag="VXF95_001482"
     CDS             complement(5537..7696)
                     /locus_tag="VXF95_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="HEV1082015.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLTYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQPAQP"
     gene            complement(7693..8289)
                     /gene="recU"
                     /locus_tag="VXF95_001483"
     CDS             complement(7693..8289)
                     /gene="recU"
                     /locus_tag="VXF95_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HEV1082016.1"
                     /translation="MVNYPHKVSSQKRQKSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKGQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            8355..8882
                     /locus_tag="VXF95_001484"
     CDS             8355..8882
                     /locus_tag="VXF95_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HEV1082017.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENEIKLAYFYQKMKNQEDYFIKRL
                     TFDQLNELAENFSEN"
     gene            8952..9281
                     /gene="gpsB"
                     /locus_tag="VXF95_001485"
     CDS             8952..9281
                     /gene="gpsB"
                     /locus_tag="VXF95_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HEV1082018.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            9302..9682
                     /gene="rnpB"
                     /locus_tag="VXF95_001486"
     ncRNA           9302..9682
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VXF95_001486"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            9767..10924
                     /locus_tag="VXF95_001487"
     CDS             9767..10924
                     /locus_tag="VXF95_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HEV1082019.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVDRELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            10937..12307
                     /gene="mapZ"
                     /locus_tag="VXF95_001488"
     CDS             10937..12307
                     /gene="mapZ"
                     /locus_tag="VXF95_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HEV1082020.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEELVETQSLDDLIQEMREAVEESEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKSAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQASSNTTS
                     EPKPSSSNETRSSRSEVNMGLSSEGVAVQRSASRVAYNQSAIDDSNNSAWDFADGVLE
                     QILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGYFVGNGAGH
                     ADDLDY"
     gene            12383..13807
                     /gene="gndA"
                     /locus_tag="VXF95_001489"
     CDS             12383..13807
                     /gene="gndA"
                     /locus_tag="VXF95_001489"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HEV1082021.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            13819..14508
                     /locus_tag="VXF95_001490"
     CDS             13819..14508
                     /locus_tag="VXF95_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1082022.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLILLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVFIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            14606..15625
                     /gene="cbpC"
                     /locus_tag="VXF95_001491"
     CDS             14606..15625
                     /gene="cbpC"
                     /locus_tag="VXF95_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HEV1082023.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDDLFDNRPVFEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPIGEVAKGWTQDFHVTIDIDRSKPAPWYYLDPTTGIM
                     QTGWQYLGNKWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNASNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(15743..16975)
                     /locus_tag="VXF95_001492"
     CDS             complement(15743..16975)
                     /locus_tag="VXF95_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1082024.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALWIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVMSIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLRLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLAMLSIIIS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAHIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(16986..17438)
                     /locus_tag="VXF95_001493"
     CDS             complement(16986..17438)
                     /locus_tag="VXF95_001493"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082025.1"
                     /translation="MFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCEGISGIILY
                     LCMYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKIQQVI
                     LACSERDDHGLLMFQGDSGKADLFDFGIGSMGVYWCLLNNKFPFDVQT"
     gene            complement(17506..17981)
                     /locus_tag="VXF95_001494"
                     /pseudo
     CDS             complement(17506..17981)
                     /locus_tag="VXF95_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811282.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="lantibiotic-modifying protein"
BASE COUNT         5622 a         3322 c         4145 g         5167 t
ORIGIN      
        1 gaggaaggag tattttttaa aaagaaaatg taaacgcttg ctcaaaaatg aaaggattta
       61 gaagtttatg aataaaggat tatttgaaaa acgttgtaaa tatagtattc ggaaattttc
      121 attaggtgtt gcttctgtta tgattggagc tgcattcttt gggacaagtc cggttcttgc
      181 agatagcgtg cagtctggtt ccacggcgaa cttaccaact gatttagcta ctgctcttgc
      241 aacagcaaaa gagaatgatg ggcgtgattt tgaagcgcct aaggtgggag aagaccaagg
      301 ttctccagaa gttacagatg gacctaagac agaagaagaa ctattagcac ttgaaaaaga
      361 aaaaccggct gaagaaaaac caaaagagga taaacctgca gctgctaaac ctgaaacacc
      421 taagacggta acccctgaat ggcaaacggt agagaaaaaa gaacaacagg gaacagtcac
      481 tatccgagaa gaaaaaggtg tccgctacaa ccaactatcc tcaactgctc aaaatgataa
      541 cgcaggcaaa ccagccctgt ttgaaaagaa gggcttgacc gttgatgcca atggaaatgc
      601 aactgttgat ttaaccttca aagaagattc tgaaaagggc aaatcacgct ttggtgtctt
      661 tttgaaattt aaagatacca ataataatgt ttttgtcggt tatgacaagg atggctggtt
      721 ctgggagtat aaatctccaa caactagcac ttggtataga ggtagtcgtg ttgctgctcc
      781 tgaaacagga tcaacaaacc gtctctctat cactctcaag tcagacggtc agctaaatgc
      841 cagcaataac gatgtcaatc tctttgacac agtgactcta ccagctgcgg tcaatgacca
      901 tcttaaaaat gagaagaaga ttcttctcaa ggcgggctct tatgacgatg agcgaacagt
      961 tgttagcgtt aaaacggata accaagaggg ggtaaaaaca gaggataccc ctgctgaaaa
     1021 agaaacaggt ccggttgttg acgatagcaa ggtgacttat gacacgattc agtctaaggt
     1081 cctcaaagca gtgattgacc aagccttccc tcgtgtcaag gaatacagct tgaatggaca
     1141 tactttgcca ggacaggtgc aacagttcaa ccaagtcttt atcaataacc accgaatcac
     1201 ccctgaagtc acttataaga aaatcaatga gacaacagca gagtacttga tgaagcttcg
     1261 cgatgatgct cacttaatca atgcggaaat gacagtacgc ttgcaagttg tggacaatca
     1321 attgcacttt gatgtgacca agattgtcaa ccacaatcaa gtcactccag gtcaaaagat
     1381 cgatgacgaa agaaaactac tttcttctat tagtttcctc ggcaatgctt tagtctctgt
     1441 ttctagtgat caaactggtg ctaagtttga tggggcaacc atgtcaaaca atacgcatgt
     1501 cagcggagat gatcatatcg atgtaaccaa tccaatgaaa gacctagcca agggttacat
     1561 gtatggattt gtttctacag ataagcttgc tgctggtgtt tggagtaact ctcaaaacag
     1621 ctatggtggt ggttcgaatg actggactcg tttgacagct tataaagaaa cagtcggaaa
     1681 tgccaactat gtaggaatcc acagctctga atggcaatgg gaaaaagctt ataagggcat
     1741 tgttttccca gaatacacga aggaacttcc aagggctaag gttgttatca ctgaagatgc
     1801 caatgcagac aagaaagtcg attggcagga tggtgccatt gcttatcgta gcattatgaa
     1861 caaccctcaa ggttgggaaa aagttaagga tatcacagct taccgtatcg cgatgaactt
     1921 tggttctcaa gcacaaaacc cattccttat gaccttggat ggtatcaaga aaatcaatct
     1981 ccacacagat ggtcttgggc aaggtgttct ccttaaagga tatggtagcg aaggccatga
     2041 ctctggtcac ttgaactatg ctgatattgg taagcgtatc ggtggtgtcg aagacttcaa
     2101 gaccctaatt gagaaggcta agaaatatgg agctcatcta ggtatccacg ttaacgcttc
     2161 agaaacttat cctgagtcta aatacttcaa tgaaaaaatt ctccgtaaga atccagatgg
     2221 aagctatagc tatggttgga actggctaga tcaaggtatc aacattgatg ctgcctatga
     2281 cctagctcat ggtcgtttgg cacgttggga agatttgaag aaaaaacttg gtgacggtct
     2341 cgactttatc tatgtggacg tttggggtaa tggtcaatca ggtgataacg gtgcctgggc
     2401 tacccacgtt cttgctaaag aaattaacaa acaaggctgg cgctttgcga tcgagtgggg
     2461 ccatggtggt gagtacgact ctaccttcca tcactgggca gctgacttga cctacggtgg
     2521 ctacaccaat aaaggtatca acagtgccat cacccgcttt atccgtaacc accaaaaaga
     2581 tgcttgggtt ggggactaca gaagttatgg tggtgcagcc aactatccac tgctaggtgg
     2641 ctacagcatg aaagactttg aaggctggca aggaagaagt gactacaatg gctatgtaac
     2701 caacttattt gcccatgacg tcatgaccaa gtatttccaa cacttcactg taagcaaatg
     2761 ggaaaatggt acaccggtga ctatgaccga taacggtagc acctataaat ggactccaga
     2821 aatgcgagtg gaattggtag atgctgacaa taataaagta gttgtaactc gtaagtcaaa
     2881 tgatgtcaat agtccacaat atcgcgaacg tacagtaacg ctcaacggac gtgtcatcca
     2941 agatggttca gcttacttga ctccttggaa ctgggatgca aatggtaaga aactttctac
     3001 tgataaggaa aagatgtact acttcaatac gcaggccggt gcaacaactt ggacccttcc
     3061 aagcgattgg gcaaagagca aggtttacct ttacaagcta actgaccaag gtaagacaga
     3121 agagcaagaa ctaactgtaa aagatggtaa aattactcta gatcttctag caaatcaacc
     3181 atacgttctc tatcgttcga aacaaaccaa tcctgaaatg tcatggagcg aaggcatgca
     3241 catctatgac caaggattta acagtggtac cttgaaacat tggaccattt caggcgatgc
     3301 ttctaaggca gaaattgtca agtctcaagg ggcaaacgat atgcttcgta ttcaaggaaa
     3361 caaagaaaaa gttagtctca ctcagaaatt aactggcttg aaaccaaata ccaagtatgc
     3421 cgtttatgtc ggtgtcgata accgtagtaa tgccaaggcg agcgtcactg taaatactgg
     3481 tgaaaaagaa gtgactactt ataccaataa gtctctcgcc ctcaactatg taaaagccta
     3541 cgcccacaat acacgtcgta acaatgctac agttgacgat acaagttact tccaaaacat
     3601 gtacgccttc tttacaactg gatcggacgt atcaaatgtt actctgacat tgagtcgtga
     3661 agctggtgat gaagcaactt actttgatga aattcgtacc tttgaaaaca attcaagcat
     3721 gtacggagac aagcatgata caggtaaagg caccttcaag caagactttg aaaatgttgc
     3781 tcagggtatc ttcccatttg tagtgggtgg tgtcgaaggt gtcgaagaca accgcactca
     3841 cttgtctgaa aaacacgatc tatatacaca acgtggttgg aatggtaaga aagtcgatga
     3901 tgttatcgaa ggaaattggt cactcaagac aaatggacta gtgagccgtc gtaacttggt
     3961 ttaccaaacc atcccacaaa acttccgttt tgaagcaggt aagacctacc gtgtaacctt
     4021 tgaatacgaa gcaggttcag acaataccta tgcttttgta gtcggtaagg gagaattcca
     4081 gtcaggtcgt cgtggtactc aagcaagcaa cttggaaatg catgaattgc caaatacttg
     4141 gacagattct aagaaagcca agaaggcaac cttcctcgtg acaggtgcag aaacagggga
     4201 tacttgggta ggtatctact caactggaaa tgcaagtaat actcgtggtg attctggtgg
     4261 aaatgccaac ttccgtggtt ataacgactt catgatggat aatcttcaaa tcgaagaaat
     4321 taccctaaca ggtaagatgt tgacagaaaa tgctctgaag aactacttgc caacggttgc
     4381 catgactaac tacaccaaag agtctatgga tgctttgaaa gaggcggtct ttaacctcag
     4441 tcaggccgat gatgatatca gtgtggaaga agcgcgtgca gagattgcca agattgaagc
     4501 cttgaagaat gctttggttc agaagaaaac ggctttggta gcagaagact ttgaaagttt
     4561 ggatgcgcca gctcaaccag gtgaaggcct agagaatgct tttgatggca atgtgtctag
     4621 tctatggcat acatcatggg gcggaggaga tgtaggcaag cctgcaacca tggtcttgaa
     4681 agaagcaact gaaatcactg gacttcgtta tgttccacgt ggatcaggtt caaatggtaa
     4741 cttgcgtgat gtgaaacttg ttgtgacaga tgagtctggc aaggagcata cctttactgc
     4801 aactgattgg ccagataaca ataagccaaa agacattgat tttggtaaga caattaaggc
     4861 taagaaaatt gtccttacag gtactaagac ttacggagat ggtggcgata aataccaatc
     4921 tgcagcggaa cttatcttta ctcgtccaca ggtagcagaa acacctcttg acttgtcagg
     4981 ctatgaagca gctttggcta aggctcagaa attaacagac aaagacaatc aagaggaagt
     5041 agctagcgtt caggcaagca tgaaatatgc gacggataac catctcttga cggaaagaat
     5101 ggtggaatac tttgcagatt atctcaacca attaaaagat tctgctacga aaccagatgc
     5161 tccaactgta gagaaacctg agtttaaact tagctcttta gcttccgatc aaggtaagac
     5221 gccagattat aagcaagaaa tagctagacc agaaacacct gaacaaatct tgccagcaac
     5281 aggtgagagt caatctgaca cagccctctt cctagcaggt gttagcctag ccctatctgc
     5341 tctctttgta gtaaaaacga agaaagacta gtatttagta aaacctctta acaagattac
     5401 ggaagcagtc tctatctttt ccaatgaggt ttatagtaca gaaaaagtct gagaagatgt
     5461 cttctcagac ttttgttaag cacataaata caatagtgct atgacaaaat cacccagaaa
     5521 atctgggtga taaatgttat ggttgtgctg gttgaggatt ctgattttgt tgatcagggg
     5581 ttgtatttga ttgttgcgta ttattgttag gattggtagt cgtactatta tttgtgcttg
     5641 gagtggttga gctagactgt gaagttgaac tatctgatga tgagcttgaa ctttcagttg
     5701 atgggggttg ttgtggagca ggtgagctcc acgtagaacg agcaccattt ttaaatacga
     5761 attctccatt tctgtagagc ccctctggta tattccaatc ctctggattg cttccttcag
     5821 acaggtaggt catcatagag cggtaaactt tggcagcgac cgtaaggcca ttgcctacaa
     5881 gtggtgtcag acggttagaa tagcctgtcc atacagccat tgaatattta cgcgtatagc
     5941 cagcaaatag ttcatcaggt gctacaaatt gagaggtctt gatgtggttt tcaatttcct
     6001 cgtctgtata gttagaggtt cctgttttac cagcctgagg gagccaagca agataggcat
     6061 ttcgtccagt tccataagtc aagactgttt tcatcatgtc ggtcatcata taggctgtcg
     6121 tttctttcat ggcacgagtt ccgacattag agaactcttt ttcactccca tcactaaaga
     6181 cgactttatg gatatacatt ggtttatagt aagttccacc atttgcaaag gcagcgtaag
     6241 cagcagccat cttttcacta cttgctccat attttttgtc tgattcggtt gtgttacttg
     6301 aaatggcatt tgagtagtga atacttgggt agtcgattcc tagaccattt aggaaagtct
     6361 tggcgcggtt gagtccgacc ttgtttagag tttccacggc tgggacgttt cgcgattgtt
     6421 gcagggcgta ttgcaaggtg atgttgccaa agtagcccct atcccagtta taaacaggag
     6481 tatttgtccc agggtagtta tagggctcat cgtgaacgat agtagcagtt gaatcgtaga
     6541 caccgtactc caaggcagga gcatagtctg tgatcggttt catagttgat ccccagtcgc
     6601 ggtttgtttc tactgcttgg ttaattccga aggaaacatt acttgactga tggcgtgctc
     6661 ctagctgggc aatgacttta ccgttagaaa catcaacaat ggtagaagcg acttgcaatt
     6721 catcgtctgg ataggcaacg tattcgtctg tattgtaaat atcccacaga tgtttttgag
     6781 cttcttggtc tacatttgtg tagacatcca tcccagttgt gagcaggtta tagcctgttt
     6841 cttcttcaac ttgattgatg acttccttga ggtaattatc catgtaagca gggtaattac
     6901 ttgctgattt gagactttgt agtccatcag taattggtgt attgactgct ttctcatact
     6961 gttcagcaga gatgtagcct tgatttttca tttcagataa gaccaagttt cggcggtctt
     7021 gggctgcttc tggatgtgaa taggggtcat attggtttgg tgcctgaggc attccagcca
     7081 gcaaggctaa ctgaggtaaa cttaaattat tgaggtcttt accatagtag ttttgagctg
     7141 ctgtctgcat tccatagttc ccattagaca tgtagacctt atttatatag taggtcaaga
     7201 tttcttgctt ggttgctttt tgttctaact gaatcgctaa ccaagcttcc tgagccttac
     7261 gagaaatagt ctggtcggaa gtcgaagttg aaaagtaagt caacttaatc aactgttgag
     7321 tgagagttga tccaccttgg agggaattgc tttgcagatt gcgcaagaaa gctcccagga
     7381 tacggatggt atcaatcccc ctgtggtcga agaagcgatg gtcttcgata gaaacgattg
     7441 ccttaaccaa atctgtggga atatcattag cttgggcatt gacgcggcgt tcagaaccca
     7501 agtcagcaat gagttgattt ttattgtcgt agattttact agaagttgtt gcaactagtt
     7561 tactctcgga taggctagga gccttgctaa cgtagtagaa aaaaactcct ccgcctaaga
     7621 caatggctgc gataaccaag cttaagaagc taatgctcag atacttgatt aggcgcagaa
     7681 tcgttggttt gttcatcttg ttttaccacc taataaatgt tctttgataa cattgagata
     7741 aggaatttga ggaaaggcac cagccttgat ttcatatcca tattctcgaa tatattcaag
     7801 tggcattgat ttttgtccct tatcttgatg atagaagcga atcaaatcga atgccggcaa
     7861 taagtaggtt tcttgctgag aagaaaagtg aagaaggaca aagcagattc cttgttgggc
     7921 aaggacttgt tccatatgct gaatctgatg tggatgaaaa tttttcatcg gaatcgcacg
     7981 tttttgtttt gtttccttga cttcaaagtc gatgtaatat ccattataaa cgccagaata
     8041 gtccgtcgtt gaagcttgtc gaaaataggc ttcaacaatc ttggcacgac ttcgttgtgg
     8101 atagtccact tgtacgattt gaataggagt tggtttctta tgtatgacag ccaagccctg
     8161 agacaaatag tagtcgttgg tagcattgat catcttttca aaagacattc ctcgatttgc
     8221 gaaatttttg ggttgagaaa gagatttttg tcttttttgt gatgaaactt tatgtggata
     8281 gttgaccata attctcctta ttggtacaat aacatcactt tattatatca taatttgcac
     8341 agaaagggtt aaaaatggct acagctttgg ttttaggcta ttctgctttt gatttgggtt
     8401 tattttctga taaggatcct cgtcttaaat tgattaaaaa agcgatacgt aaagatttag
     8461 aggctatggc agcagatggg gtgtcttggc ttgtgtttac aggaagtttg ggttttgaat
     8521 attgggtttt agaggttgct caggagatga aaaccgaata cggtttccag ttggccacca
     8581 tttttgcttt tgaaacccat ggggaaaatt ggaatgaagg caatcagatg aaactgagtc
     8641 gctttaagca ggtagacttt gtcaaatatg cttatcctcg ctatgaacac aaggggcagt
     8701 taagagatta ccagcagttt ttgctggaaa acacgactag ttcctatctt ttttatgatg
     8761 aagaaaatga aataaaacta gcttattttt accaaaagat gaaaaatcaa gaggactatt
     8821 ttataaagag attaacattt gatcaattaa atgaacttgc tgaaaatttt tccgaaaatt
     8881 gaagctttga ccttgatttt tgtttgcctt tttttatata ataatactag caagcgagaa
     8941 tggagagaga catggcaagt attatttttt cagcgaaaga tatttttgaa caagagtttg
     9001 gacgtgaagt ccgtggctat aataaagtag aagttgacga gtttttagac gatgtcatca
     9061 aggactatga aacctatgct gccttggtca agtcacttcg tcaggaaatt gcggatttga
     9121 aggaagaatt aactcgtaaa ccgaaacctt caccagttca agcagaaccc cttgaagcgg
     9181 caattacaag ttctatgacg aattttgata ttttgaaacg cctgaataga ttggaaaaag
     9241 aagtttttgg taaacaaatt ttagataact cagattttta agtagttatt tgagatgtgc
     9301 aatttttgga taatcgcgtg aggagaattg cttctcatga ggaaagtcca tgctagcaca
     9361 ggctgtgatg cctgtagtgt ttgtgctagg cgaaaccata agcctaggga cgagaaatcg
     9421 ttacggcagt tgaaatggct aagtccttgg ataggccaga gtaggcttga aagtgccaca
     9481 gtgacggagt ctttctggaa acagagagag tggaacgcgg taaacccctc aagctagcaa
     9541 cccaaatttt ggtcggggca tggagtacgc ggaaacgaac gtagtattct gactgctatc
     9601 agctagagct gttagtggta gacagatgat tatcgaagga agtggtccta gtcacttctg
     9661 gaacaaaaca tggcttatag aaaattgcat ataggttggg gctgagaaat tttctcaacc
     9721 tcatttttta aagtggacat atagaaaggt cttgcaagac tgtaacatga aaaaagaatt
     9781 taatttaatt gcaactgtgg cagcagggct tgaggctgtc gttggtcgtg aagtgcgaga
     9841 gttgggctac gattgtcagg ttgaaaatgg acgtgttcgt tttcaaggag acgtgagagc
     9901 tattatcgaa accaaccttt ggcttcgggc agcagatcgt atcaaaatta tcgtaggaac
     9961 gttcccagct aagacttttg aagagctatt tcagggagtt ttcgctttag attgggaaaa
    10021 ttatttacca cttggagctc ggttcccgat ttcaaaagct aaatgtgtta agtccaaact
    10081 tcacaatgag cccagtgttc aggctatttc taagaaagct gttgtcaaga aattgcagaa
    10141 acactatgct cgcccagaag gggttcctct gatggagaat ggtccagagt ttaagattga
    10201 ggtctctatt ctcaaagatg tggcaactgt catgattgat acgaccgggt ctagcctctt
    10261 taaacgtggt tatcgtaccg aaaaaggtgg cgctcctatc aaggaaaata tggcagcagc
    10321 cattttacaa ctttctaact ggtatccaga caagcctttg attgatccga cctgtggttc
    10381 ggggactttc tgtattgagg cagttatgat tgctagaaag atggcgccag gtcttcgtcg
    10441 ctcttttgca tttgaggaat ggaactggat cagcgatcgc ttgattcaag aagtgcgcac
    10501 agaagcggct aaaaaagtag accgtgagct tgagctggat atcatgggct gtgatattga
    10561 tgctcgcatg gtggaaattg ctaaggccaa tgctcaggca gctggtgttg caggagacat
    10621 tacttttaag cagatgcgcg tgcaggattt acgttccgat aaaatcaatg gagtaatcat
    10681 ttccaatccg ccttatggtg aacgtttgtc agatgatgca ggggtgacca agctctatgc
    10741 tgagatgggg caagtatttg caccgctgaa aacttggagc aaatttatcc tgactagtga
    10801 tgaagctttt gaaagcaagt atggtagcca agcagataag aagcgtaagt tatacaacgg
    10861 aaccttgaaa gtggatctgt atcaatattt tggtcagcgt gtcaaacggc aagaggtaaa
    10921 atagaaaggg atactcatga gtaaaaaaag acgaaatcgt cataaaaaag aaggtcaaga
    10981 accgcaattt gattttgatg aagcaaaaga gctaacagtt ggtcaagcta ttcgtaaaaa
    11041 tgaagaagtg gaagcaggag tcttgcctga ggattccatt ttggacaagt atgttaagca
    11101 acacagagat gaaattgagg cggataagtt tgcgactcgt caatacaaaa aagaggagtt
    11161 agttgaaact cagagtctgg atgatttaat tcaagagatg cgtgaggctg tagaggagtc
    11221 agaagcttct tcggaggaag ttccatcttc tgaagacatc ttactaccct tgcctctgga
    11281 cgatgaggag cagggcttgg atcctctatt gttagatgat gaaaatccaa cagaaatgac
    11341 tgaagaagtg gaagaggagc aaaacctttc tcgtctggat caagaggact cagaaaagaa
    11401 aagtaaaaaa ggctttattt tgaccgtttt ggcgcttgta tcagtaatta tttgtgtcag
    11461 tgcttattat gtctaccgtc aagtggctcg ttcgaccaag gaaattgaaa cttctcaatc
    11521 aactacagcc aatcaatcgg atgtggatga ttttaataca ctttatgacg ccttttacac
    11581 agatagcaat aaaacggctt tgaaaaatag ccagtttgat aaactgagtc aactcaaaac
    11641 cttgcttgat aaactggaag gtagtcgtga acatacgctt gccaaatcta aatatgatag
    11701 tctagcaacg caaatcaagg ctattcaaga tgtcaatgca caatttgaaa aatcagctat
    11761 tgtggatggt gtgttggata ccaatgccaa agccaaatcg gatgctaaat ttacggatat
    11821 taaaactgga aatacggagc ttgataaagt gctagataag gctattagcc ttggtaagag
    11881 ccagcaaaca agtacttcta gctcaagttc aagtcaagca agctcaaata cgacaagtga
    11941 gccaaaacca agtagttcaa atgagactag aagtagtcgc agtgaagtca atatgggtct
    12001 ctcgagtgaa ggggttgctg ttcaaagaag tgccagtcgt gttgcctata atcagtctgc
    12061 tattgatgat agtaataact ctgcctggga ttttgcggat ggtgtcttgg aacaaattct
    12121 agcgacttca cgttcacgtg gctatatcac tggagaccaa tatatccttg aacgtgtcaa
    12181 tatcgttaac ggcaatggtt attacaacct ctataagcca gatggaacct atctctttac
    12241 ccttaactgt aagacaggct actttgtcgg aaatggcgct ggtcatgcag atgacttgga
    12301 ctactaagca gtcgttacaa aattctttct tttcaaaagt aaaaatgata aaataaaaca
    12361 aatgaaacaa gaggagtgtc aaatgacaaa agctaacttt ggtgtcgtag gtatggccgt
    12421 aatgggtcgt aaccttgccc ttaatattga atcacgtggt tacacagttg ctatctacaa
    12481 ccgtagtaaa gaaaaaacgg aagatgtgat tgcttgccat cctgaaaaga attttgtacc
    12541 aagctatgac gttgaaagtt ttgtaaactc aatcgaaaaa cctcgtcgta tcatgctgat
    12601 ggttcaagct ggacctggta cagatgctac tatccaagcc cttcttccac accttgacaa
    12661 gggtgatatc ttgattgacg gaggaaacac tttctacaaa gataccatcc gtcgtaatga
    12721 agaattggca aactcaggta tcaactttat cggtactgga gtttctggtg gtgaaaaagg
    12781 tgcccttgaa ggtccttcta tcatgcctgg tggacaaaaa gaagcctacg aattggttgc
    12841 ggatgttctt gaagaaatct cagctaaagc accagaagat ggcaaaccat gtgtgactta
    12901 catcggtcct gatggagctg gtcactatgt gaaaatggtt cacaatggta tcgagtacgg
    12961 tgatatgcaa ttgatcgcag aaagctatga cttgatgcaa cacttgctag gcctttctgc
    13021 agaggatatg gctgaaatct ttactgagtg gaacaagggt gaattggata gctacttgat
    13081 tgaaatcaca gctgatatct tgagccgtaa agacgatgaa ggccaagatg gaccaatcgt
    13141 agactacatc cttgatgctg caggtaacaa gggaactggt aaatggacta gccaatcatc
    13201 tcttgacctt ggtgtaccat tgtcactgat tactgagtca gtgtttgcac gctacatttc
    13261 aacttacaaa gaagaacgtg tacatgctag caaggtgctt ccaaaaccag ccgccttcaa
    13321 ctttgaagga gacaaggctg aattgattga aaaaatccgt caagcccttt acttctcaaa
    13381 aatcatttca tacgcacaag gatttgctca attgcgtgta gcctctaaag aaaacaactg
    13441 gaacttgcca tttgcagata tcgcatctat ctggcgtgat ggctgtatca tccgttctcg
    13501 tttcttgcaa aagattacag atgcttacaa ccgtgatgca gaccttgcca accttctttt
    13561 ggatgaatac ttcttggatg ttactgctaa gtatcaacaa gcagtgcgtg atatcgtagc
    13621 tcttgcggtt caagctggtg tgccagtgcc aactttctca gcagctatta cttactttga
    13681 tagctaccgt tcagctgacc ttccagctaa cttgatccaa gcacaacgtg actactttgg
    13741 tgcccacact taccaacgta aagacaaaga aggaaccttc cactactctt ggtatgacga
    13801 aaaataagta ggtcagccat ggggaaacgg attttattac ttgagaaaga acgaaatcta
    13861 gctcattttt taagtttgga actccagaaa gagcagtatc gggttgatct ggtagaggag
    13921 gggcaaaaag ccctttccat ggctcttcag acagactatg atttgatttt attgaacgtt
    13981 aatctgggag atatgatggc tcaggatttt gcagaaaaat tgagtcgaac taaacctgcc
    14041 tcagtcatca tgattttaga tcattgggaa gacttgcaag aagagctgga agttgttcag
    14101 cgttttgcag tttcatacat ctataagcca gtctttatcg aaaatctggt agcgcgtatt
    14161 tcggcgatct tccgaggtcg ggacttcatt gatcaacact gcagtctgat gaaagttcca
    14221 aggacctacc gcaatcttag gatagatgtt gaacatcaca cggtttatcg tggtgaagag
    14281 atgattgctc tgacccgccg tgagtatgac cttttggcga cacttatggg aagcaagaaa
    14341 gtattgactc gtgagcaact gttggaaagt gtttggaagt atgaaagtgc gaccgagaca
    14401 aatatcgtag atgtctatat ccgctatcta cggagcaagc ttgatgttaa aggtcaaaaa
    14461 agctacatta aaaccgtgcg tggtgttggt tacaccatgc aagaatagaa aagcagttgc
    14521 agttgtgtaa ctgctttttt gaggagtttt tatatattga catgcagtcg ggtctttgct
    14581 acaatcgttt taggaggata tatagatgaa acttttgaaa aaaatgatgc aagttctact
    14641 agcagtcttt ttctttggtt tgctagctac aaatacggta tttgcgaata ccacaggtgg
    14701 ccgatttgtt gataaggata atagaaaata ttatgtaaaa gatgatcata aagcaatcta
    14761 ttggcataaa atagacggta aaacttacta ttttggtgat attggagaga tggttgtcgg
    14821 ttggcaatac ttagaaattc ctggaacagg ttatcgtgat gatttatttg ataatcgtcc
    14881 agtcttcgaa attggccttc aggagaagtg gtactatttt ggacaagatg gtgctttgct
    14941 agaacaaaca gataaacaag tactagaggc aaaaacgtct gaaaatacag gaaaagtata
    15001 cggtgaacaa tatcctctat ctgctgaaaa gagaacttat tattttgata ataattatgc
    15061 tgtaaagaca ggctggattt atgaagacgg caattggtat tatttaaata agctaggaaa
    15121 ttttggtgat gattcttaca atccactacc aattggtgaa gttgctaagg gttggactca
    15181 agattttcat gttactattg acattgatag aagcaaacct gctccatggt actacctaga
    15241 tccaacaact ggtattatgc aaacaggttg gcaatatcta ggtaataagt ggtactacct
    15301 ccgttcctca ggagcaatgg ccactggctg gtatcaggaa ggtaccactt ggtattattt
    15361 agaccagcca aatggcgata tgaaaacagg ttggcaaaac cttgggaaca aatggtacta
    15421 tctccgttca tcaggagcta tggcaactgg ttggtaccaa gatggttcaa cttggtacta
    15481 cctaaatgca agtaatggag atatgaagac aggttggttc caggtcaatg gcaactggta
    15541 ctatgcttat agctcaggtg ctttggcagt gaatacgacc gtagatggct attctgtcaa
    15601 ttataatggc gaatgggttc ggtaatgaca gggcgcttat aattatatta gaacactcgc
    15661 ttaatcaaag aagtgacttt gttgtacttg acctgacgat tggggagatt aaaagcatgt
    15721 gaaatctaca catgcttttt cgttagttat gagtgttgaa cttgactaac cattgacaaa
    15781 agataagagc aatcaaaata agatacaaaa atatcaatgc taactgcacc gaaacgcccg
    15841 atgctatgga cagggctaat agggagagca gggacggggc gagaatgtct actgtgctca
    15901 gagcagagcc caccgtcccc atcttgtcac tggggatatg ggcaaagaca gctgcttgta
    15961 ggcgagggct gagaatgccg ataatcgtag aactgatgaa actggtcatg aaaattacga
    16021 tataggcttg acaaaggata ctagttatta gagccaatag ggaaatctca cagaaaacca
    16081 agaggtgcgt gaaacggata tttttaaata gattactgct ggtcatattg ccaaggatag
    16141 ctccacaaga aatgatgatg gagagcatgg cgaggagttg cccaatgctc agttgtgcta
    16201 gtgtctgttg gatgaagcgg agggcaatca gccgagggga cacatccaag atggcaatca
    16261 tactggtcgt cagaaacagt agtatgacgg tatcttttaa cctcaggagc acagccagcg
    16321 actgtttaag atgttgaaaa tatttcttaa aactcagtgc tgtatgtgac atttcaatcc
    16381 ttttttcaac ctcatacaag gtatgtcgaa taacatacag gcccaaaaag gcaatgacaa
    16441 aagtcagagt gttgataagg gaaatagttt gaatactcat aacattgata aggaatgcgc
    16501 cagccagatt ggcgacaatg cggacaaccc tcatcagaga ctgcctgaac cccatggcat
    16561 catgcaggtc gtccttaatt acactgatgt agagggcgtt catcatgtag gcagacaggt
    16621 agctcaaggt gtcagagatg aggttgatga tgacaatcat aatgactgaa actaatgaaa
    16681 agggcgacaa gacgagaaat actgtcaaaa tagcgtagag caggattttg attttggcaa
    16741 tccagagtgc gtgtttgact ctattttctt gaaaatctcc tagaatcccg agaaagagtt
    16801 gcgatagtag gggaaccatc tctgaaatgg aaatcagtaa aattgctagc ggagcgaaat
    16861 tgtactgagc cacataattg ataatggcga ggtagaaaat actgtcgccg aatgatgaaa
    16921 aacagctgtt tagcagcaac tgtctatata tgttgtttgt ccaaaataat ttcatacttt
    16981 tctccttatg tctgcacatc gaatgggaat ttattattta atagacacca atataccccc
    17041 atgcttccta ttccgaagtc aaacaaatct gctttaccac tatctccttg aaacatcagt
    17101 aaaccgtgat catctcgttc agaacatgct aaaattacct gttggatttt tttcatcagt
    17161 aatttgtttt gattgtagac agtggtttgt agtaagctag ttattccgtg gcaatatcct
    17221 gtcatcattt ttagatgatg gttaaaaaca aattcttgat atttactaat aatatctttg
    17281 tttccgtcac aatcgtacat acaaagatat aagattattc cggaaattcc ttcgcaccaa
    17341 gaaagttgta aatttcctaa attttcagta ttagaagtaa ctttttctaa taattttttt
    17401 aattcagtat ggaatgtatg gagatcatta tagaacatag aaggttctaa gactttagaa
    17461 taggcaaata aagcctatgc aattccacaa tatccatgag caaagctata gtctaaaatg
    17521 ctttctttgg ctatatctct ttgtaggaaa taatgctaaa tttcccctat actattgtgg
    17581 atgaaaattt taagagtatt gtcattggta aattgatagt attttattaa tgataatagg
    17641 acaccagatt ttcccaatgc aaagtctatt tcctctagag tatcataatt ctctattaat
    17701 ttcttagcgg agacgtttgc taattgtaga tagtattgat ttttactgat agaaaataaa
    17761 tgtaggagta accatagata gcctgcatca ccaaatagca gtgagtattg atatttatat
    17821 gtgtgtgtcg ttctaattgt cactgccttc ttgatgatag agagtatttt agaatccagt
    17881 tctggggggt acaatttatt tagaggaaac agtagtccag ctattccgtg ttggaatgat
    17941 aaattactta cgaaatttcc aaattctgtt gaagaagtga tccttccttc agaatttaca
    18001 gttttatcta gtaaaaatcg tagaacacta ttacattctg ttttgtaatc atatttatgt
    18061 tcctctattt ttttaatttt gactaaatta tttgtttgac ttaaatttag tagacattgt
    18121 aaccaaaata gttgctcatc tgtgagctga ccttgagtat gtgatagttc tagtaattga
    18181 ataggatcct ttagttagat tcaatcaatc tataacacaa caacataata atacttttag
    18241 gataacttgt caaata
//
LOCUS       DAVLMQ010000035        17558 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000035 DAVLMQ010000000
VERSION     DAVLMQ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17558
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.035"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(127..1062)
                     /locus_tag="VXF95_001495"
     CDS             complement(127..1062)
                     /locus_tag="VXF95_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HEV1082026.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTSIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAGSLFKATAPITRNELIIEIWRTFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GFAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1059..1919)
                     /locus_tag="VXF95_001496"
     CDS             complement(1059..1919)
                     /locus_tag="VXF95_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1082027.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKSPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2027..4189
                     /locus_tag="VXF95_001497"
     CDS             2027..4189
                     /locus_tag="VXF95_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HEV1082028.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHNVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIYKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLEHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQFLSYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKNLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4281..5540
                     /locus_tag="VXF95_001498"
     CDS             4281..5540
                     /locus_tag="VXF95_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082029.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADDTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            5554..6420
                     /locus_tag="VXF95_001499"
     CDS             5554..6420
                     /locus_tag="VXF95_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1082030.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIITIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFLQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSIVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            6434..7267
                     /locus_tag="VXF95_001500"
     CDS             6434..7267
                     /locus_tag="VXF95_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1082031.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7578..9020
                     /gene="gtfA"
                     /locus_tag="VXF95_001501"
     CDS             7578..9020
                     /gene="gtfA"
                     /locus_tag="VXF95_001501"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HEV1082032.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKRLGERYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKDLFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9158..10351
                     /locus_tag="VXF95_001502"
     CDS             9158..10351
                     /locus_tag="VXF95_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HEV1082033.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11037..13016
                     /locus_tag="VXF95_001503"
     CDS             11037..13016
                     /locus_tag="VXF95_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1082034.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVQVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13083..14579
                     /locus_tag="VXF95_001504"
     CDS             13083..14579
                     /locus_tag="VXF95_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1082035.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGTLTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPVTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            14579..15505
                     /locus_tag="VXF95_001505"
     CDS             14579..15505
                     /locus_tag="VXF95_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1082036.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            15514..16581
                     /locus_tag="VXF95_001506"
     CDS             15514..16581
                     /locus_tag="VXF95_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082037.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKEWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            16592..17518
                     /locus_tag="VXF95_001507"
     CDS             16592..17518
                     /locus_tag="VXF95_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082038.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQNIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQTELARYQKGLN"
BASE COUNT         5168 a         3123 c         3679 g         5588 t
ORIGIN      
        1 gttttaatga gagtttgtaa ctctcttttt tgtttttaga gacaataaaa cttcagatcc
       61 gtaaaactta attgaattac taatctgaag ttatttttat atcgtttata ttataattgt
      121 gttattttac ttccaactat tgagagaaat ttcgccacta tttagccaga tttcttttcc
      181 gttatcacat tgaactaaaa gttttccatt ttctgagatg tctttagcaa atcccttgta
      241 gtctttttgc tctagtgtga aagtgacttc ttttcctaga atgaatgact gttttttgta
      301 taggtataat agctcttctg ctggtgtttc gaagaaagta cgccagattt ctatgatcaa
      361 ttcattcctt gttataggag ctgtagcttt aaataagctg ccagcttttt cttttaattc
      421 ctgagggaag tctttaatag tgaaattgat acctactcca ataatgatat ctgtgactaa
      481 gccagtttct acagaggtca ttgcttcagt aaggattcct ccaattttat gattgtttag
      541 atagatatca ttgacccatt ttatgtcgac atctattaaa gttaggttct taatggcttt
      601 gtagacagct ccagctacaa gtagtgtgta ggatggtaat ttgtcatagg ggagatttgg
      661 tttaagatgg agtgtcatat aaataccacc ttgtggtgag tagaaggaac gttgaaaacg
      721 gcctcggcct gctgtttgat aggaagctag atagagggta tttgcttcat ggcctaaatc
      781 aattgcttct tttgcatcta gttgtgttga ttttgtttcg ggtttaaagc tgactttaat
      841 tggaagattt tcttctagaa tctctggaag aataaggtca ccattcatca gtttataccc
      901 tctatttttg atactatcaa tttcaatgcc ttcttgttct agtcgcttga tggctttcca
      961 aattgatgtt cggcttaggg atagtttttc tgcgattttt tctccgctga tatagtcggt
     1021 ttctttagat aggatttggt agacagcttg gtaggatttc ataatgttgc ctttcttact
     1081 agttggtatt gagagtattc ttttcttgta tgacttggag tctgattaaa gtattgttta
     1141 taagctttcg aaaaatggag tggatctgaa aaacctaccg agtatgcaat taccttgatg
     1201 gactcttggg tattttcgag aagttgtcta gctcggtgca ttcgaacgta gagtaggtat
     1261 tctttgggtg ataaggtatt aaattctttg aatacgcttg ataagtagct tctgtgaacg
     1321 gatagttctt ttgctaaatc ttgaattgta agtgattgag gatagtggct atcaattaat
     1381 cgtttgcatt caagatagag ttggtgggtt gatgaaatat tctttttttt ctgattggga
     1441 gcaatagttc ccagatgaaa catcagttca tgaagttgtc ccatgatatg gagttgagct
     1501 aattcacttg attttgtaat ctgagcgaag cggacaatgt ctgagatgag ttttgcagta
     1561 gtctgggtat gacaagtttc agattggatg agataggatt gatcagaaat ttgagaaaga
     1621 gcaaaataat caggggattt ccctccagtg attcctaacc agtagtaggc ccaaggttct
     1681 ttactatctg cttgataaaa ggttagttcc tctggtttta atagaaagaa atctccttct
     1741 tttaaatcaa caattttacc cttgtaatga aattttcctt gtcctttagt aatgtaatgt
     1801 aggacgtatg tatcacgaat ggctggacca aaagagtaat taggtgtgca ttcctcatat
     1861 ccataaaagc ttagggcaag gtcgattgtt ccagtctggt attctgaaaa aactaacatg
     1921 tgctacctcc tacctaacat tttaccatat tcttgagaca tttttctatt ttagaaagcg
     1981 atttcaggtg ataaaatata atcaataaag tgatgaggtg aagtaaatgg gagttaggat
     2041 agagaataat ctattttatg ttgagagtaa aaatctaagt ttgattattg aaaatcgaaa
     2101 tggctactta cttttgaaac atttaggaaa gactattaag aactataaag gttccaatag
     2161 tgtttatgaa cgagaccatg ccttttcagg aaatccaaca gctactaatc gaacctttag
     2221 tttagatact caacgtcaaa tttttggaca acatggctta ggagatttta ggaaaccaac
     2281 catacaggtt cagcataatg taactgaagt aacagacttt cgatttgtag aagcaaagat
     2341 tttaaaaggt cagaatggtc cacagggctt accttctcca catagcatgg acgatacaga
     2401 gactcttgtc ttaatgttag aagattctaa ggctcaactt agtctgactt tgtattatac
     2461 tacttttaat aatgatgcga ctattgctag ctacagtaaa ttagataata atagtaatca
     2521 ggaagttgtc atctataaag atttttcttt tatggctgat tttccagctg cagattacga
     2581 aatagtaact ctgcagggtg cttatgctcg tgaaaagact gttagacgtc aacaggtaga
     2641 acaaggaatc ttttcgatta gttcaaaccg aggtgcttct ggtcatgctc aaacaccagc
     2701 tcttctacta tgcgaacaag gagtcacaga ggatgctggg aatgtgtttg ctattcaact
     2761 aatgtatagt ggcaactttg aagcttttgt tcaaaaaaat caattgaatg aagttcgggt
     2821 ggctattggc attaatccag aaaacttttc ttggaagtta gcccctgagg aatactttga
     2881 aacaccggta gctttagtga ctcattcaga tcagggatta actggtatta gtcatgaaag
     2941 tcagaatttt gtactggagc acattatgct aagtgaattt tctaaaaaag aacgtccaat
     3001 tctaatcaat aactgggaag ctacttactt tgactttcag agagaaaaac tgttagagtt
     3061 agcagatgaa gctaagaaag ttggcattga actttttgta ttagatgatg gttggtttgg
     3121 caatcgtttt gatgataatc gtgctttagg tgattgggtt gttaatgagg aaaaactggg
     3181 tggaagtcta gaaagtctga tttcagctat ccatgaaaga ggtttgcagt ttggactttg
     3241 gttagaaccc gaaatgattt ctgtagatag tgatttgtat cgtcaacatc ctgactgggc
     3301 tattcaggtt cctggctatg agcatactta ttctcggaat caattagtac ttaatcttgc
     3361 caatcctcag gtagtagaat acttgaaaag tgtcttagat caattcctat cttatcatga
     3421 tattgattac attaaatggg atatgaaccg caatatcact aagctaggga atggattaac
     3481 ttatctagag acacagatgc aatctcatca gtacatgctg gggctttacg aactcgtttc
     3541 ttatctgaca gagaagcaca gccatattct ctttgagtcc tgctctggtg gtggtggacg
     3601 aaatgatctt ggtatgatgc gctatttccc acaagtctgg gctagtgata atactgatgc
     3661 cattgcacgt ttaccaattc aatacggttc atcctatctc tatccaacca tttctatggg
     3721 ggctcatgtg tcagcagtac cgaatcatca gatgggacga atgacaccat tagaaacacg
     3781 tggccttgta gcaatgatgg gaaatttggg ctatgaactt gatttgacaa atttatcaga
     3841 tgaagagaaa gctacgattg ctaatcaggt gaacttgtat aaagaattac gaccagtagt
     3901 tcagttagga cagcagtata gactaattaa tcctgatact gtatccaatg aagcagctgt
     3961 acaatttaat tacggaaatc aaacgattgt aacctacgtt cgcgttttat ctgttgtaga
     4021 gaccatggaa acaactttaa aattaaaaaa tttggatgaa gagggactat ataaattaca
     4081 ggaaaatggc gaagtttact caggtgcaga actaatgtat gcgggcctaa ctgttatctt
     4141 atcccaagga gattttttga gtagacagta tatttttaga aaactatgat atgtactgac
     4201 ctcaaaagtt agatttattc tatctaactt ttgaggtgca gtttgataag ggtgtataaa
     4261 tttataaagg aggctttcta atggaatggt ataaaaaaat cggacttctt gcaactacag
     4321 gtttagcttt gtttgggctc ggtgcttgct ccaactatgg taaatctgcg gatgacacag
     4381 tgaccatcga gtatttcaac cagaaaaaag aaatgaccaa aaccttggaa gaaatcactc
     4441 gtgattttga gaaggaaaac cctaagataa aggtcaaagt cgtcaatgta ccaaatgctg
     4501 gtgaagtatt gaagacacgc gttctcgcag gagatgtgcc tgatgtggtc aatatttacc
     4561 cacagtccat cgaactgcaa gaatgggcaa aagcaggtgt ctttgaagat ttgagtaaca
     4621 aagactacct gaaacgcgtg aaaaatggct acgctgaaaa atatgctgta aacgaaaaag
     4681 tttacaacgt tccttttaca gctaatgctt atggaattta ctacaacaaa gataaattcg
     4741 aagaactggg cttgaaagtt cctgaaacct gggatgaatt tgaacagtta gtcaaagata
     4801 tcgttgctaa aggacaaaca ccatttggaa ttgcaggtgc agatgcttgg acactcaatg
     4861 gttacaatca attagccttt gcgacagcaa caggtggagg aaaagaagca aatcaatacc
     4921 ttcgttattc tcaaccaaat gccattaaat tgtcggatcc gattatgaaa gatgatatca
     4981 aggtcatgga catccttcgc atcaatggct ctaagcaaaa gaactgggaa ggtgctggct
     5041 ataccgatgt tatcggagcc ttcgcacgtg gggatgtcct catgacacca aatgggtctt
     5101 gggcgatcac agcgattaat gaacaaaaac cgaactttaa gattgggacc ttcatgattc
     5161 caggaaaaga aaaaggacaa agcttaaccg ttggtgcggg agacttggca tggtctatct
     5221 cagccaccac caaacatcca aaagaagcca atgcctttgt ggaatatatg acccgtccag
     5281 aagtcatgca aaaatactac gatgtggacg gatctccaac agcgatcgaa ggggtcaaac
     5341 aagcaggaga agattcaccg cttgctggta tgaccgaata tgcctttacg gatcgtcact
     5401 tggtctggtt gcaacaatac tggaccagtg aagcagactt ccataccttg accatgaact
     5461 atgtcttgac cggtgataaa caaggcatgg tcaatgattt gaatgccttc tttaacccga
     5521 tgaaagcgga tgtggattag gagtagagag actatgaaaa aagtattaca aaaatattgg
     5581 gcatgggctt ttgtggtcat ccccctcttg ttacaagcaa ttttcttcta tgtgccgatg
     5641 tttcaaggag ccttttacag ttttaccaac tggacaggat tgacttacaa ctacaaattt
     5701 gtcggcttaa acaactttaa gctcctcttc atggatccaa aattcatgaa tgcgattggc
     5761 tttaccgcaa tcattacgat tgccatggtg gttggtgaga ttgcactcgg gatcttcatt
     5821 gcgcgtgtct tgaactctaa aatcaaaggc caaaccttct tccgtgcttg gttcttcttc
     5881 ccagctgttt tatctggttt gacagtggct ttgatcttca agcaagtctt caactacggt
     5941 cttccagcga ttgggaatgc ccttcatatt gaatttctcc aaaccagtct tttagggact
     6001 aagtggggag caatctttgc ggctgtcttt gtccttcttt ggcaaggggt ggctatgccc
     6061 atcatcatct tcctagctgg tttgcaatct attccaactg agattacaga ggcagcaagg
     6121 attgatggtg cgactagcaa gcaagttttc tggaacattg aattgcctta cttgctacca
     6181 agtgtctcta tagtctttat cctagcccta aaaggtgggc tgactgcctt tgaccaagtc
     6241 tttgccatga ccggtggtgg tccaaacaat gccacaacct cacttgggct cttggtttat
     6301 aactatgcct ttaaaaacaa ccaattcggt tatgccaatg ccattgccgt aatcttgttc
     6361 ttcttaattg tagtgatttc gatcatccaa ttgagagtat ctaagaaatt tgaaatttaa
     6421 gaggagaagc atgatgaaac aagatgaaag aaaagccctg attggcaaat acattctatt
     6481 gattctagga tcggttctga ttttagtgcc gctccttgct accctcttta gttccttcaa
     6541 acccactaag gatattgtag ataatttctt tggctttcca accaacttca catgggacaa
     6601 ctttagccgt ctcttagctg atgggattgg aggctattat tggaactctg tcgtcatcac
     6661 tgtcttgtct ttacttgcag taatgatctt tatccctatg gcagcctact ccatcgctcg
     6721 caatatgagt aaaagaaaag cctttaccat catgtatacc ctcttaatcc tcggaatctt
     6781 cgtacctttc caagtcatca tgattccgat tacggttatg atgagtaaac tcggtttggc
     6841 taataccttt ggtttgatct tgctctactt gacctatgcg attccacaga ccctctttct
     6901 ctatgttggc tatatcaaaa tctcgattcc agaaagtctg gatgaagcag cagagatcga
     6961 tggggctaat caatttacaa cctatttccg catcatcttc ccaatgatga aaccgatgca
     7021 tgcgacaacc atgattatca atgccctttg gttctggaat gacttcatgt tgccactcct
     7081 tgtcttgaac cgggattcca aaatgtggac tctgcctttg ttccaataca actacgcagg
     7141 ccaatatttc aacgactacg gaccaagctt tgcctcttac gtggtcggca ttatcagtat
     7201 caccattgtc tatctcttct tccaacgcca tatcatttca ggaatgagca acggggcagt
     7261 gaagtaatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcag gctgtacttg
     7321 agtacggtaa ggtgaagctg acgtggtttg aagagatttt cgaatagtat aagaagagct
     7381 catggaatct atagtctttg acacagagga agagttcagc ttgttgataa ttctatgtag
     7441 aaaacaagaa agtagtactt tgtttatcac agtctatatt agtacgagtt tgatgataaa
     7501 tagagattta aaatgaattt tatttatgaa gccagatcat atgagacttg gcttcaatta
     7561 gaaaaaggag agtaatgatg ccaattcaaa ataaaaccat gttgattacc tattctgata
     7621 gccttggaaa taatcttaaa gacttatatg ataatttgga agagcatttt ggagatgcta
     7681 ttggaggagt tcacctttta ccatttttcc catcaacagg tgatcgtgga tttgcgccag
     7741 ttgactacga cgaagtggac tcagcttttg gtgattggga ggatgttaag cgtttaggtg
     7801 agagatatta tcttatgttt gattttatga ttaatcatat ttctcgtcaa tccaagtatt
     7861 ataaggacta tcaagaaaaa catgaagcca gtgaatttaa agatctcttt ttaaactggg
     7921 ataagttttg gccagaaaac cgtccgacac agtctgatgt agatttaatt tacaagcgta
     7981 aggatcgtgc accaaagcaa gagattgtgt ttgaagatgg ttcagtggaa catttgtgga
     8041 atacctttgg tgaggagcag attgatcttg atgtgaccaa agaagtaact atggaattta
     8101 tccgtaagac cattcagcac ttggcaagta atgggtgtga tttgattcgt ctagatgcct
     8161 ttgcttatgc agtgaagaaa ttggatacta atgatttctt tgtggaacca gatatttggg
     8221 atttattgga caaagttcga gatatcgctg ctgagtatgg gacagagctt ttacctgaga
     8281 ttcatgaaca ctattcgatt cagtttaaaa tagcagacca tgattactat gtttatgatt
     8341 ttgctcttcc aatggtgaca ctttatactc tttacagttc cagaacagag cgtttggcta
     8401 agtggttaaa gatgagcccg atgaagcaat ttacgacgct agatacccat gatgggattg
     8461 gagtagtaga tgtcaaggat atcctgaccg atgaggagat tgactatgct tcaaatgaac
     8521 tctataaggt tggagccaat gtcaaacgta agtactctag tgccgagtat aacaacttag
     8581 atatctacca aatcaattca acctactatt cagcgcttgg agatgatgat gtcaagtatt
     8641 ttctcgctcg tctaattcaa gcttttgccc caggtattcc tcaggtttac tatgtgggtc
     8701 tattagcagg caagaatgac ttgaaattat tagaagaaac taaagaaggt cgaaatatta
     8761 atcgtcatta ctatagcaac gaggaaatag caaaagaagt gcaacgacct gttgtgaagg
     8821 cccttctcaa tctattttct ttccgtaacc gttcagaagc ctttgatcta gaagggacta
     8881 ctgagataga gacaccaaca gctcacagca ttgtaatcaa acgtcaaaat aaagataagt
     8941 ccgtaacagc agtagcagaa attgatttgc aaaatcagac ttatcgggta attgagaatg
     9001 gagttgaagt aacattttga agccttgata tggtggataa aatagggttt ttattttgga
     9061 aaacgtttcc tttgttttca aattgctaaa aaagtggtac aatataggat agcttactat
     9121 tatctgaatc agctgatttg gagagaaagg attcattttg aaatcaatag gctttattga
     9181 aaagctgaag gggttgtcta gtaaagagct gattttattg ggaattatcc taagtatctt
     9241 tttacccttt tatctttttg tagttgtact ctgtttatat attatcagtt tgatttttac
     9301 aggagacatg aaaagtattc ttcagaaaat gggggagcat ccgatgctgc ttctttttct
     9361 tagctatagt actgttatat ccattcttgc acaaaattgg atgggtcttg tggcttcagt
     9421 aggaatgttt ctatttacta ttttcttttt gcactatcag tcgattttat cccataaatt
     9481 ctttcgattg attttgcagt tcgtcttgtt tggtagtgtc ttgtcagctg cttttgccag
     9541 tttagaacat ttccaaattg tgaagaaatt taactatgct tttctttcac ccaatatgca
     9601 ggtgtggcat cagaaccggg cagaagtgac cttctttaat cctaattatt atggaattat
     9661 ttgttgtttc tgtattatga ttgctttcta tctgtttaca acgaccaagt tgaattggtt
     9721 gaaagtattc tgtgtgattg caggctttgt taatctcttt ggtttgaact ttactcaaaa
     9781 tcgaactgcc tttcctgcta ttatcgctgg agcaattatc tatctcttta cgactattaa
     9841 aaactggaag gccttttggc ttagtattgg ggtcttcgcg attggtttga gtttcctctt
     9901 ttctagtgat ttgggagttc gaatgggtac tttagactct tctatggaag aacgcatttc
     9961 tatctgggat gctgggatgg ccttgtttaa gcaaaatcct ttttggggtg aagggccatt
    10021 gacctatatg cactcttatc ctcggataca tgctccttat catgaacatg cccacagtct
    10081 ttatattgat acgattctga gttacggaat tgtgggtacc attttattag ttctgtcttc
    10141 tgttgctcct gttcgcttga tgatggatat gagtcaggag tcggggaaac gtccgattat
    10201 cggcctttat ctatctttcc ttacagtggt tgctgtgcac ggaatttttg acttggctct
    10261 cttctggatt cagtcaggct ttattttctt gctagttatg tgcagtattc cattggagca
    10321 tcgaatgttg gtatcggaca tgacggatta agttttataa gtttgaaatc ttctaccttg
    10381 ggtaggagat tttttatacg atgggcatgt cgtggatctg aggtgtaagt cctctgtagg
    10441 gatccactac cggtgaatac aatagcgctc cccaagcctg actatcgtga ggtagcggat
    10501 taaaatggtc tggggataga tcgttttaag tctgacgcag gaaataagaa ttgtcagaga
    10561 aagcaatagt gaaatcgtag gctatgaata gaaacgtgat agcgaggagc atatagtgga
    10621 caaggtagcg agaaatttta aagtataaaa gatagtctta atctatatgt gtaaatcacg
    10681 aaagtaattg aattcggaat aaggttggtg tgaaaagaca tagtaaactg aatcttgaat
    10741 actagaatga tacttctaca atattgttat aatttaattt gaattccaaa atcacattgt
    10801 tccgtccgta tttcatttta ctgtatgtct tcctaagctc caaaatttct gtgtcaaatt
    10861 tcctattttc actgtagtct ttgacacttc gaacgacaat ttgaatcata tattcaaaaa
    10921 aaaatgaaaa atttgtgcca acaagcctaa atattctgaa aatttgtttg atttttaatg
    10981 gataatgtga tataatggtt gtcaatctat aattcacata aacagaggag tagaaaatga
    11041 aaaaaaatcg tgtatttgct acagcaggtc ttgttttatt agcagcaggt gtacttgcag
    11101 catgcagttc ttcaaaatca tctgattcat cagcccctaa agcttatggc tatgtttata
    11161 cagcagaccc agaaaccttg gactacctga tttcaagtaa aaatagtaca acagtagtga
    11221 cttcaaatgg gattgatggt ttattcacta acgataatta cggtaatctt gctcctgcag
    11281 ttgcagagga ttgggaagtc tctaaggatg gtttgaccta cacttataag attcgtaaag
    11341 gggttaaatg gtttacctct gatggagaag aatatgcaga ggtgacggct aaagatttcg
    11401 tgaacggttt aaaacacgca gcagataaaa aatcagaagc tatgtattta gctgaaaatt
    11461 cggttaaagg cttggcagat tatctatcag gaacttcaac agatttttca acagttggtg
    11521 tcaaggcggt tgatgattat acgttacaat acactttgaa ccagcctgaa ccgttctgga
    11581 actctaagtt gacctattct attttctggc ctctgaatga agaattcgaa acatcaaaag
    11641 gaagcgattt tgctaaacca acagatccga catccttgct ttataatggt ccattcttgt
    11701 tgaaagggtt gactgcaaaa tcttctgtag agtttgtaaa aaatgagcaa tattgggata
    11761 aagaaaatgt ccacctagat actatcaatc tagcttacta tgatggatca gatcaggagt
    11821 cgctagagcg taacttcact agtggagctt atagttatgc ccgtctttac cctaccagct
    11881 ccaactattc taaggttgca gaagaataca aggacaatat ctattacaca caatcaggct
    11941 ctgggattgc tggtctgggt gtgaatattg atcgccaaag ttacaactat acctctaaaa
    12001 ctacagattc agagaaagta gctactaaga aggcattgct taacaaagat ttccgtcaag
    12061 ccttgaattt tgctcttgat cgctcagctt actcagctca aatcaatggt aaagatggag
    12121 cagctttagc agttcgtaat ttatttgtaa aaccagactt tgtttcagct ggtgagaaga
    12181 cctttggtga tttagtcgct gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga
    12241 atttagctga tgggcaggat ggtttattca atgctgacaa ggccaaggca gagtttgcga
    12301 aagctaagaa agctttagaa gcagacggcg ttcagtttcc tattcatctg gacgttccag
    12361 tagaccaagc atcaaaaaac tacatatctc gtattcagtc ttttaaacaa tctgtagaaa
    12421 cagttcttgg tgttgaaaat gtcgttgttg atattcaaca aatgacaagt gatgaattcc
    12481 ttaatattac ttactatgct gccaatgctt catctgagga ttgggatgta tcaggaggag
    12541 tttcatgggg tccagactat caagacccat ctacttacct ggatatttta aaaacaacta
    12601 gcagtgaaac tacaaaaaca tatttaggat ttgataatcc aaatagccct tcagtagttc
    12661 aagttggttt gaaagaatac gataaattag ttgatgaagc tgccagagag acaagcgact
    12721 tgaatgtccg ttatgaaaaa tatgcagcgg ctcaagcatg gttgacagat agttcactct
    12781 ttattcctgc tatggcttct tctggtgcag caccagtgct ttcacgaatt gttccattta
    12841 ctggagcttc tgcgcaaaca ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat
    12901 tacaagataa agtggtgact aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag
    12961 aaaaagctga atcaaatgag aaagctcaaa aagaattggc aagtcatgtg aagtaaataa
    13021 tttctaatag aactttctct ccatgaggag aaggttcttt tgggattttt aaaggaaata
    13081 atatgaaaaa atatattttt atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa
    13141 cgactttgac ctacacgatt atctatacct tggttcctcg aaaattgatt ttcaagcagg
    13201 atcctaacta taataaaatt gcgacaacgg ctgataaacg tgataactat gaaaatactg
    13261 tgtttgagcg tatgggctac attgagtatt acgatactaa agagttgcaa gaaaaggcaa
    13321 gtagcatgga ttcttctgta acagtagaag caaatgcgac taataaagct atttatgaaa
    13381 agtacatcaa tcaattaggt catggttgga ctttgggaga atttactgaa agtggtcaat
    13441 tctatgctac tcgtgaaatt ccaatttttg aacgtgtttt tcacttctat gctaacttga
    13501 ttgacattga ccatacaaat aaaatccaag accctgaaaa tccagacttg aaacgctacc
    13561 ttcgttttga aaatgatcca gctatcggat ggtcattggt cggttcagga actaaacata
    13621 aatatctctt gtactttaac agtcagttcc catttgttca tcaaaacttt gtgaacttga
    13681 atttaggtga ctcttaccca acctatgcta atacaccagt tcttcaggtt attactcaag
    13741 gtcaaggaca aaccaaaact gcccaagttc agttcccaac aggtaagaaa acgtcttctg
    13801 taaatattta ctcaagaacc tacaagtcac ctagtcaggc tgactctcgt gaagtagcta
    13861 gctatgggaa agatgatcct tatacagcga ctgaaagtaa ttaccaatat ccatctatga
    13921 ttgtcagctc tgctattact ggtttgattg gtttggttct tgcctatgct cttgccgtgc
    13981 cacttggttc agccatggct cgtttcaaga acacttggat tgatagcctc tcaacaggga
    14041 ctttgacctt cttgcttgct cttccaacga ttgccttggt ttacatcgtt cgattgattg
    14101 gatcatctat tgcccttcca gattcattcc ctatcttggg agctggagat tggcgttctt
    14161 acgttttacc agcagtcatc cttggtttgt tgggtgctcc tgttacagcc atttggattc
    14221 gtcgttacat gattgacttg caatctcaag actttgttcg tttcgctcgt gcaaaaggtt
    14281 tgtctgaaaa agaaatttca aacaaacaca tctttaaaaa tgccatggtt ccgctggttt
    14341 caggaattcc tggtgccatt attggggtta tcggtggtgc aacccttact gaaacagtct
    14401 tcgccttccc aggtatgggt aaaatgttga ttgactctgt aaaagcatct aataactcta
    14461 tggtcgttgg tcttgtcttc atctttacat gtatttctat cttctcacgt cttttgggag
    14521 atatttggat gactattatt gacccacgta ttaaattgac tgagaaagga ggcaaataat
    14581 gtctacaatc gataaagaaa aatttcagtt tgtaaaacgt gacgattttg cctctgaaac
    14641 tattgatgcg ccagcatatt cttactggaa atcagtgttt aaacaattta tgaagaaaaa
    14701 atcaactgta gtcatgttgg gaatcttggt agccatcatt ttgataagtt tcatctaccc
    14761 aatgttttct aagtttgatt tcaatgatgt cagcaaggta aacgacttta gtgttcgtta
    14821 tatcaagcca aatgcggagc attggttcgg tactgacagt aacggtaaat cgctctttga
    14881 cggtgtctgg ttcggagctc gtaactccat cctcatttct gtgattgcga cagtgattaa
    14941 cttggttatc ggtgtttttg tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt
    15001 catgatggaa gtttacaacg tcatctcaaa catcccacct cttttgattg ttattgtctt
    15061 gacttactca atcggagctg gattctggaa tctgattttt gccatgagcg taacaacatg
    15121 gattggtatt gccttcatga tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa
    15181 cttggcgtca cgtactttgg gaacaccaac cttgaagatt gttgccaaaa atatcatgcc
    15241 tcaattggta tctgttattg tgacaaccat gactcaaatg cttccaagct ttatctcata
    15301 cgaagccttc ttgtctttct tcggtcttgg attaccgatt acagtgccaa gtttgggtcg
    15361 tttgatttcg gattattcac aaaacgtaac aaccaatgct tacttgttct ggattccatt
    15421 gacaaccctt gtcttggtat ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc
    15481 tagtgatcca cgtacacata gataggagta gaaatgacaa aagaaaaaaa tgtaattttg
    15541 actgctcgcg atattgtcgt ggaatttgac gttcgtgaca aagtattgac agccattcgc
    15601 ggcgtttccc ttgaactagt tgaaggagaa gtattagcct tggtaggtga gtcaggatca
    15661 ggtaaatctg ttttgacaaa gaccttcaca ggtatgctcg aagaaaatgg tcgtattgcc
    15721 caaggtagta ttgactaccg tggtcaggac ttgacagctt tatcttctca caaggagtgg
    15781 gaacaaattc gtggtgctaa gattgcgact atcttccagg acccaatgac tagtttggac
    15841 cccattaaaa caattggtag tcagattaca gaagttattg taaaacacca aggaaaaaca
    15901 gctaaagaag cgaaagaatt ggccattgac tacatgaata aggttggcat tccagacgca
    15961 gatagacgtt ttaatgaata cccattccaa tattctggag gaatgcgtca acgtatcgtt
    16021 attgcgattg cccttgcctg ccgacctgat gtcttgatct gtgatgagcc aacaactgcc
    16081 ttggatgtaa ctattcaagc tcagattatt gatttgctaa aatctttaca aaacgagtat
    16141 catttcacaa caatctttat tacccacgac cttggtgtgg tggcaagtat tgcggataag
    16201 gtagcggtta tgtatgcagg agaaatcgtt gagtatggaa cggttgagga agtcttctat
    16261 gaccctcgcc atccatatac atggagtctc ttgtctagct tgcctcagct tgctgatgat
    16321 aaaggggatc tttactcaat cccaggaaca cctccgtcac tttatactga cctgaaaggg
    16381 gatgcttttg ccttgcgttc tgactacgca atgcagattg acttcgaaca aaaagctcct
    16441 caattctcag tatcagagac acattgggct aaaacttggc ttcttcatga ggatgctcca
    16501 aaagtagaaa aaccagctgt gattgcaaat ctccatgata agatccgtga aaaaatggga
    16561 tttgcccatc tggctgacta ggaggaagga aatgtctgaa aaattagtag aaatcaaaga
    16621 tttagaaatt tccttcggtg aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt
    16681 ctttatcaac aagggagaaa ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac
    16741 tattggtcgt gctatcatcg gtctaaatga tacaagtaat ggagatatca tttttgatgg
    16801 tcaaaagatt aatggtaaga aatcgcgtga acaagctgcg gaattgattc gtcgaatcca
    16861 gatgattttc caagaccctg ccgcaagttt gaatgaacgt gcgactgttg attatattat
    16921 ttctgaaggt ctttacaatc accgtttatt taaggatgaa gaagaacgta aagagaaagt
    16981 tcaaaatatt atccgtgaag taggtcttct tgctgagcac ttgactcgtt accctcatga
    17041 attctcaggc ggtcaacgtc aacgtatcgg tattgcccgt gccttggtca tgcaaccaga
    17101 ctttgttatt gcagatgagc caatttcagc cttggacgtt tctgtacgtg cccaagtctt
    17161 gaacttgctc aaaaaattcc aaaaagagct cggcctgacc tatctcttca tcgcccatga
    17221 cttgtcggtt gttcgcttta tttcagatcg tatcgcagtt atttacaagg gtgttattgt
    17281 agaggttgca gaaacagaag aattgtttaa caatccaatt cacccatata ctcaagcctt
    17341 gctttcagcg gtaccaatcc cagatccaat cttggaacgt aagaaggtct tgaaggttta
    17401 cgacccaagt caacacgact atgagactga taagccgtct atggtagaaa tccgtccagg
    17461 tcactatgtt tgggcgaacc aaaccgaatt ggcacgttat caaaaaggac taaactagta
    17521 atggttttat aatttccatg tcaattttta tggaaatt
//
LOCUS       DAVLMQ010000036        17393 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000036 DAVLMQ010000000
VERSION     DAVLMQ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17393
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.036"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(807..2057)
                     /gene="ilvA"
                     /locus_tag="VXF95_001508"
     CDS             complement(807..2057)
                     /gene="ilvA"
                     /locus_tag="VXF95_001508"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HEV1082039.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIQTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(2107..2463)
                     /locus_tag="VXF95_001509"
     CDS             complement(2107..2463)
                     /locus_tag="VXF95_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1082040.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(2701..2937)
                     /locus_tag="VXF95_001510"
     CDS             complement(2701..2937)
                     /locus_tag="VXF95_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082041.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERAGATKSARYIAKWILRNKKH"
     gene            complement(3044..4066)
                     /gene="ilvC"
                     /locus_tag="VXF95_001511"
     CDS             complement(3044..4066)
                     /gene="ilvC"
                     /locus_tag="VXF95_001511"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HEV1082042.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(4132..4608)
                     /gene="ilvN"
                     /locus_tag="VXF95_001512"
     CDS             complement(4132..4608)
                     /gene="ilvN"
                     /locus_tag="VXF95_001512"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HEV1082043.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(4601..6301)
                     /locus_tag="VXF95_001513"
     CDS             complement(4601..6301)
                     /locus_tag="VXF95_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HEV1082044.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTVEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVQFHA
                     "
     gene            complement(6502..8169)
                     /locus_tag="VXF95_001514"
     CDS             complement(6502..8169)
                     /locus_tag="VXF95_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HEV1082045.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDTVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(8172..8537)
                     /locus_tag="VXF95_001515"
     CDS             complement(8172..8537)
                     /locus_tag="VXF95_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1082046.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(8694..8882)
                     /locus_tag="VXF95_001516"
     CDS             complement(8694..8882)
                     /locus_tag="VXF95_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HEV1082047.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(8998..9174)
                     /locus_tag="VXF95_001517"
     CDS             complement(8998..9174)
                     /locus_tag="VXF95_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
                     /protein_id="HEV1082048.1"
                     /translation="MDLDIVVRKSIDELWDLDLTAIPLAAVRDDFYTHNFNSGVLLIN
                     NGMWRAENVTQDLI"
     gene            complement(9285..9483)
                     /locus_tag="VXF95_001518"
                     /pseudo
     CDS             complement(9285..9483)
                     /locus_tag="VXF95_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808887.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 8"
     gene            complement(9911..11455)
                     /locus_tag="VXF95_001519"
     CDS             complement(9911..11455)
                     /locus_tag="VXF95_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HEV1082049.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIREAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKEDERFASLEDGDKLFGSNPFYDQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLETFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAIQLYKNYQTGEYMLGAVGQLQFEVFKHRMEGEYNAE
                     VVMSPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            11668..11970
                     /gene="gatC"
                     /locus_tag="VXF95_001520"
     CDS             11668..11970
                     /gene="gatC"
                     /locus_tag="VXF95_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HEV1082050.1"
                     /translation="MKITQEEVTHVANLSKLRFSEEETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVVEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            11970..13436
                     /gene="gatA"
                     /locus_tag="VXF95_001521"
     CDS             11970..13436
                     /gene="gatA"
                     /locus_tag="VXF95_001521"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HEV1082051.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGIDPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLNSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            13436..14878
                     /gene="gatB"
                     /locus_tag="VXF95_001522"
     CDS             13436..14878
                     /gene="gatB"
                     /locus_tag="VXF95_001522"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HEV1082052.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVELEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEVQRQAEILRSGGQIRQETRRYDEANKATILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDASQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            15007..15567
                     /gene="efp"
                     /locus_tag="VXF95_001523"
     CDS             15007..15567
                     /gene="efp"
                     /locus_tag="VXF95_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HEV1082053.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            15589..15978
                     /locus_tag="VXF95_001524"
     CDS             15589..15978
                     /locus_tag="VXF95_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HEV1082054.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            15971..16393
                     /gene="nusB"
                     /locus_tag="VXF95_001525"
     CDS             15971..16393
                     /gene="nusB"
                     /locus_tag="VXF95_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HEV1082055.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(16442..16678)
                     /locus_tag="VXF95_001526"
     CDS             complement(16442..16678)
                     /locus_tag="VXF95_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082056.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(16691..17164)
                     /locus_tag="VXF95_001527"
     CDS             complement(16691..17164)
                     /locus_tag="VXF95_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082057.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(17182..17367)
                     /gene="briC"
                     /locus_tag="VXF95_001528"
     CDS             complement(17182..17367)
                     /gene="briC"
                     /locus_tag="VXF95_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HEV1082058.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
BASE COUNT         5158 a         3922 c         3149 g         5164 t
ORIGIN      
        1 aaaaaaaaca tatattcaac gaaaataatt agttcagaat tttcttactt cctttttaaa
       61 tccgataata tataggtttt gctagcctct acaccataaa tatttgctaa taaaaatact
      121 gtattattac cctcttaagg tgcgaaatta ttcaagttct taaaaaatgc ttctctattt
      181 ccgtaagata gcttatttct tcgatttaag aactgaagat gatagttcta acctttagaa
      241 atccaagcct tcactagctc aaaaactcct atctttcttc ctcaataaat catctgagag
      301 ataggtattc cttatgtcct tcaaattcat cactcctttg gatattgagg tgctagccta
      361 gaagcagaca cccgattatc taaaccatcc ttaatagaga tgacaagaca gataagctca
      421 gttaattact tatatatctt tttaatatgg tatatttgtc aacaaaaaga aatcaaatca
      481 taccttatac tcaatgaaaa tcaaagagca aactaggaag ctagccgcaa gttgctcaaa
      541 acactgtttt gaggttgcag atagagctaa cgtggtttga agagattttc gaagagtatt
      601 aaagacagtg tgactatgct tgtcaataga taggaaatca aaatgaagga tggaaatctg
      661 agccaaacat cataagtgct ataatgaaca gaagtaagaa ttgcacgata agttttctaa
      721 aaccatagga atcgtcccct ttcttcatct tcattatagc atatatacat cagttgtaca
      781 aataatatga tattttttat tagtcctcag acaagcatat tataaagcgt ttcattacca
      841 tttaagttaa tataagctgg atcaaaacct tccattctac gaatcaaacc tgcataatca
      901 tgcttatctg ctaaagcgat cccaattaat actgggcctg ttcccttgct agctcgtttg
      961 atatactcaa aacgtgtgat atcatcattt ggccccagga tatcatttac aaactcacgc
     1021 aaagctcctg gacgttgtgg gaaattgacc acaaaataat gtttgatacc atcataaatc
     1081 aaggcacgct cttccatttc tggcatacgg ttgatatcat tatttcctcc agaaatgata
     1141 caacaaatgg ttttcccctt aatatattca gctaaaacct ctaaagaggc gatactagct
     1201 gctccagcag gttctgcgac tatcccttgc ttagagtaaa ggtcaatcaa ggtttcagaa
     1261 atcaatccct catcgacacc taccaaagtt tgaatatgtt gacgagttgc ttcataggtc
     1321 aactgaccta ccttttgcac agcaatccca tccgcaaatt tatcaatttc cttgagtttg
     1381 actggacctc cagcctcaaa ggcagctttc atggaacgcg ctccattcgc ctctactccg
     1441 ataacctcaa tctctggact tgtttccttg atataggtag aaaccccggc aatgagaccg
     1501 ccaccaccaa caggaaccaa gacagcatca aaatcaatcg attcttttcg agcttcttct
     1561 aaaatctcat aagcaactgt tccttgacct gcttgaacat gagcatcatc aaaaggatca
     1621 ataaaggtac gattttcaga gactgtaaat tcttgagctg ctttggctga ggcatcaaag
     1681 gtatctccaa ctagtttaat agttacaaaa tccccaccaa aaaagcgaac ctgaccaatc
     1741 ttttgttgtg gcgtagtaat gggcataaag atagtagcag gaattttcat ttcattacaa
     1801 gtataggcta ctccctgcgc atgatttccc gcagaagcgc agactacccc acgttcacgt
     1861 tcttccttgc tgagctggga aatggcataa taggcaccac gaattttaaa ggagcgaaca
     1921 cgctgggcat tttctttttt caaataaatc ttagcaccat acttctccga taaataatga
     1981 tcgtaatcca gtggagtatt cacaaccaca ccgttcaaga ccttgtgagc cttgattata
     2041 tcttttgaac ttaacatata aaacctcttt ttctataaaa aacagtcact aatgactgtt
     2101 ttttagttat tcatctccga aaacttcagt aacactttca tggtatttat gagccatacg
     2161 aatcgaaaac tctttaggaa gttcataacg atttgtggaa atccaatcat ataaccattc
     2221 taccaaactt tcttcactat cattacgatg gaagataaaa tagtttaaaa tttctttata
     2281 ttctacatca ttcaaatcca acgtgtctac aaattgacta cgaggaacaa aattagaatc
     2341 taattttctt agttgatctg tcaattctcc caattgtaaa tccaactgaa aaaatagttt
     2401 ttgcagttgc ctatcagttt catcacatcc tgtcttgata gaaaacaaat tggtaatatt
     2461 catatgattt caacccctaa ataagtacat ctaatatccc acgaatagct aaagctaaag
     2521 ttttcgcagt ccagtcattt aaacccgatt ctttcaatcc agatgcaata atttgctcta
     2581 tttgatataa accgctatct atcgtctcat ttattctgcg aagaggacct tcaatatagg
     2641 ataaagcttc tccgaatcta acagctgatt taggtcctaa tgatttacca actatatttg
     2701 ttaatgtttt ttatttctca aaatccattt cgctatataa cgagcagatt tagtcgcacc
     2761 agctctctca aacggagaat gaatttcaag accttcttct ctagctattt gtgccaattt
     2821 gaagaattgt tcaaaggtca tatgcaacct accatcttca aaattagcat catcataaat
     2881 gttaattaca gcattttcat catacgacca atctgcttta ttttggtctg ctagcactat
     2941 taccgacggt gtaattacat tatacaacta gaaccaataa taacgatgca atttttctca
     3001 taatcttttt cataaaatca tctccagcgc tatatatttc taattagtta tagattttga
     3061 atgcatcatc gtcgttttta ccaacgaatg gcattgcttt acgcaattct gcaccaactt
     3121 tttcaatttc aaggttagct gcttgttcac ggtaagcagt caattttgga cgtccagctt
     3181 tatagtcatt tacaaagtca tttgcaaatt taccattttg gatgtctgcc aagacagcct
     3241 tcatattttc tttaacttgt tcagtgatta cacgtggacc tgatacatag tcaccgtatt
     3301 cagcagtgtt tgaaatagat tgacgcattt tcttgaatcc accttcgtag atcaagtcaa
     3361 cgatcaattt catttcgtga agaacttcaa agtaagccaa ttctggagcg taacctgctt
     3421 ctgtcaagac ttcgaaacct gcttcgataa gggcagtcaa accaccacaa agtacagctt
     3481 gttcaccaaa caaatcttct tcagtttctt ctttgtaagt tgtttcaaga agacctacac
     3541 gagccgctcc aacaccttta caccagtcca tagcaatgtt tttagcattt cctgttgcat
     3601 cttggtatac tgcataaaga gctggaacac caaatccttc ttcgtaagta cgacgtacca
     3661 agtgtcctgg tcctttagga gcacacatga agacatctac atccgcagga actttgataa
     3721 attcaaagtg gatgttgaaa ccatgggcaa atccaactgc gtttccagct tccaagtttg
     3781 gagcgatttc tgcttcgtac aattcttgtt gaatttcgtc tggcgccaag atcatgataa
     3841 catcagccaa cttagtagct tctgctactg tgtaagtatc aaatccatct tcttttgctt
     3901 tatcaaaaga tttacctgga cgtacaccta taataacgtc acgacctgaa tcacgcaagt
     3961 tttgagcatg cgcatgccct tgtgaaccat aaccgataac ggcgattttt ttaccgtcaa
     4021 gtgctgctac tttaacatct ttttcatatt ccatttgaac tgtcatagct tttctctctt
     4081 ttctattatt tattgccttt taggctggtt taataaattt aagttggatt tttaatcgcg
     4141 ggtaaatcca gttgcacccg ttcgagcaat attgcgaata ccgtatgggc gaatgactct
     4201 caatagggct tcgctctttt ctgcatttcc cgtcatctga atggtaatcg agcttggcgc
     4261 tacgtctacc actgttgcac ggaaaggttg aataatcgct aaaatctcag ctctcttctc
     4321 agctggcgct gacatcttaa ccaaaatcac ctcgcgctcc aaatgaggct tgtctgtaat
     4381 atctcgaatg cgaatcacat caatctgacg attgagctgt ttgatgattt gctccacttc
     4441 atcatgagaa gcaacatcaa taataatagt gatacgcgat acattcggat cttctgttgc
     4501 tccaacagag atgctttcaa tattaacctg acgacgagat aggacacctg taaagcgatt
     4561 gaggactcct gaacgatttt gtagttttgc tgttaacatt ctacgcatgg aactgcaccc
     4621 ccaacatctc atgattactc ttaccagccg gtaccattgg taacacctgt tccttacgag
     4681 aaatatctac ctcaattagc ataggaacat cctcagtgat gacttcaagg tcttgagcca
     4741 aggtctcagg attgtcaaac ttatagtttt taataccata agcctgcgcc atcaattgga
     4801 aatcaggaag ggtatcaaag accgactctg atgttctgcc ttcatagaag gattcctgcc
     4861 actggcgaac cattccgagt gaatgattgt tcagcataac caccttgatt ggcaccttgt
     4921 aaatattcaa aatagccaac tcctggttgg tcatttggaa accaccatcc ccaacaaaca
     4981 agactacttc cttatctggg ttagcaattt tagcaccgat tgctgctgga attccaaagc
     5041 ccattgttcc caaaccacct gaagtcacta actgacgttc attttggtag ggataatact
     5101 gagctgtcca catttggtgt tgaccaacgt ctgttaccac aatggcatct ccattcgtca
     5161 attcaccaat tcgttcaata actgcttgcg gttgaaccac acgctctttc ttgtcataag
     5221 aacgaacacg attcttgtct ttagtgactt tctcaatcca cttttcagta ttgttgtgaa
     5281 ctgttggttc tgctagcaac atttgcaagg ccttcttagc atctccaact acaggaatgt
     5341 ctgcactgat aatcttgcca atctcagctg ggtcaatatc aatgtgggca accttagcat
     5401 tcttagcgaa agtcttagga ttccccgtca aacggtcatc gaaacgagaa ccaatactaa
     5461 tcataaagtc cgcttccgtc atggcaatat ttgctgcgaa tgacccgtgc atgcctccca
     5521 ttccaagaaa gagtgggtga ctcgttgcaa tcgttccttg tcccaaaaga ctggttacca
     5581 ctggaatttg atagcgttct gcaaattcat ttagttccgt agcagcctca gcataactaa
     5641 ttccaccacc agctaacaag actggctttt tagccttgga caattgcttc aagattttct
     5701 tgatttgcat atcattcggc tcaacagtcg gctgataact tggtaaattc acttctggtg
     5761 aataaatgaa gtctgtttct aaagcagata tgtcttttgg taggtcaatt acaactggcc
     5821 ctggacggcc tgtagttgcg atatggacag cttccgtaat gatacgcgga atatcagctg
     5881 tctcacgaac ttggtaattg tacttagtga ttggcatggt aattcctacg atgtctgcct
     5941 cctgaaaggc atccttccca atccctgctc gcgccacctg acctgtaaag accaaaaggg
     6001 gaacgctatc gctcatagca tccgcaatcc ctgtaatggc atttgttgct cctggtccac
     6061 tagtgacgac ggcaacaccc aactttccag ttgatttggc ataaccttca gcttcatgca
     6121 aacaaccttg ctcatggcgc cctagaatgt ggcgaatgcc tttaaaatta tatatcgcat
     6181 cataaaaagg caaaaccgca ccaccaggat aaccaaagat ggtatcaact cctaaatcac
     6241 gaagtgtttc caaaactagg tccgaccccg tcttaggaga ttctaaactg attttctcca
     6301 ttgttcccct ttctttcctc ttaaaaataa cttgttacta tcataccatt ttttcaaaat
     6361 ttttcaagat aaaagaagaa attttctgaa ttttctattt taacgtttat ttatgaatgt
     6421 tatttttgtt tttattaaaa agataccgat ttcatttact aaaaaagaaa aaagaactga
     6481 tttctcagtc cttcattaat cttattccac actaaatagg tatgggtaaa caggttgttg
     6541 accttggtga atctcgactt caacgtcttc gaattcttct acgatttctt gagcgatttc
     6601 attggcaagt tcttcgcttc cgtcttcacc gacatagaag gttacgattt cactgtcttc
     6661 atccaacata tgtttcaagg tttcagtcaa tgtttggtgc atatcagggt ttgacacaag
     6721 aatttttcca tccaccatac ctagattatc gttttcatgg atttctaagc catcgatcgt
     6781 tgtatcacgc acggctgttg tgacgcttcc gctaacgaca tcgctaagag cagctgtcat
     6841 acgctcttgg ttttcttcaa tggacttgct tggatcaaag gcaagaagac ttgtcatacc
     6901 ttgaggaaga gtgcgagcct ctaccactac tgctggttgc tccaaaactt ctgccgcaga
     6961 ttgagctgcc atgaagatgt tcttgttgtt tggcaagaag atgatgttac gggcattgac
     7021 ctgttcaaca gccttgataa agtcttctgt tgaagggttc atggtttgac cgccttcgat
     7081 aacatagtcc acgccttgag aacagaagat atctgctaga cctttaccag ccaccacagc
     7141 aattaaagca tactcttttt cttcagccga cttgataact tgagtagctt ctttctcaac
     7201 ctgtgcttcg tgttggttac gcatattgtc aacttttacc ttgaccaagc taccatattt
     7261 gagaccttct tgcataacaa gtcctggatc ttctgtatga acatggactt tgacaatttc
     7321 atcatcgtta acaacgagga gagaatcccc aagctcatcc aagtagttac ggaattcatc
     7381 gtagtcaaaa tctttagcat aggttggacc ttgcttaaga gctaccatga tttcagtaca
     7441 gtaaccaaac gtgatgtcct cagtcgctac gtgaccagct acagacttat gatgctctac
     7501 attgatcatc tcactcatgt tggcaggagt cgctacaaag tcctcagatg caatatattc
     7561 gccagtaagg gctgaaagga aaccttcgta gatgaagacc aatccttgac cacctgagtc
     7621 cacaacgcca acttctttca atactggaag catgtctggt gttttagcta gagctgtttt
     7681 agcaccttcc aaggctgcgc gcatgacttc aacagtgtca tctgtttgct cagctttttt
     7741 cttagcaccg atagcagctc cacgagaaac tgtcaaaatc gttccttcaa caggtttcat
     7801 cactgcctta taggcaactt ccacacctga ttggaaggcc agagccaagt cttgacctgt
     7861 taactcgtct ttatccttga tagcttggga aaatccacgg aaaagctgag acgtaatcac
     7921 tcctgagttc ccacgcgcac ccatcaaaag ccctttggca agaatgctcg ctacttctcc
     7981 aactgtagaa gctggcttgt ctgcaacttc tttagcacca ttttcaatgg tcattcccat
     8041 atttgtccca gtatctccat ctggaactgg aaagacgttt aatgaattga catattcagc
     8101 ttgcttattc aagcgagttg atgcagcctg caccatttct tgaaataagc tagtagtaat
     8161 ttttgacacg gttattctcc tacaactttg atattttgaa tgtagacatt tacagtctga
     8221 gcagtaattc caagctggtt ttccaagcta aaggcaacac gctcttgaat gttttttgac
     8281 acttcactaa tctttgttcc gtagcttaac acggtatata catcaactgc aatactgcca
     8341 tcttcggctg cctttacgac gacaccttta gaataatttt ccttacctag cagggcttgg
     8401 aaattatctt tgagggcatt tttactagcc ataccgacca caccaaaaat ctcagttgct
     8461 gctccaccta cgacggttgc aatcacttca tctgttagtt cgatttgacc atcttttgta
     8521 ttaattttta cagtcatcct ttttacctca actagttgat actctatttt atcatatttc
     8581 agcccaagtg taaaagcaga atgatgtatc agcggatatt tactctattt ttcaaacgat
     8641 gttataccca caataaaaga aaaaagaccc taaggtctcc tttgctttta ttattaaacg
     8701 cgttcaactt tacctgattt caaagcacga gctgaagccc aaactttttt aggtttacca
     8761 tcgataagaa cagtaacttt ttgaaggttt ggttttacgg cacgttttgt ttggttcatc
     8821 gcgtgtgaac ggttgtttcc tgatacagtc ttacgacctg taaagtaaca tactttagcc
     8881 attgtgtttt cctcctatta gatctaatat agcggatgtg ctagcaccac ataccgtact
     8941 atgttatcac actttcttgt tttttgcaag ggaattggaa gattttttat ttgtgtctta
     9001 aatcaggtct tgcgtgacat tttctgctct ccacatgcca ttgttgatta acagaacacc
     9061 agaattaaaa ttatgtgtat aaaaatcatc tctaactgca gctaagggta tagccgtcaa
     9121 gtccaaatcc cacagctcgt ctatcgattt tcttacaaca atatctaaat ccaaatacag
     9181 tacacgagac tcgcttacat actttggaat aaaatatcta aaaaagccgc atatgaaagt
     9241 ccctcaaagg ggagacgata acctttcaga atactactgt caatctaaac attcacaatc
     9301 tcactattca aagtctctag tcttttttcc atcaattgga accattctcg cggaaggtca
     9361 tcattaaaaa cataaaactt aagattataa tagatgaaca caaagagatt ttattgttgt
     9421 ttcaacttta tccatataag cattatctgc acctaagaca atcgcttttt tctcttcttt
     9481 cactctttat ctcatttctt tttattccca tcatatgttt ctacgtaacc attattttcg
     9541 cccattcgtt cgtaaaacca taccagtgga gattttagat gaagtcccat tacggtttac
     9601 aatttttaca ttacgacacg gagttttaca aatcgatttc atttgccaaa cgtagttagt
     9661 aaggcagtta gctaggctac ctactttctg ctacgacgga aaaatccaca aatcaatacc
     9721 attcgtggat ttttcctagt gaagcgttta ggtaagccgc catagcggtt accgattatt
     9781 agattacgac acggagtttg gcaaatcgat tctatttgcc aaacgtagtt agtgaggcag
     9841 ttagctagtt cgccaaatag cgactagcgt ccaacaattt ggaactttag ttccaattgt
     9901 tgatactgag tcacatcttc tcctctaact ctacgtctgg atacttgtcc gcaaaccagc
     9961 ggagggcaaa gtcattttca aagagaaaga ctggttggtc aaaacggtct ttggctaaga
    10021 tattgcgact tgacgacatc cgttcatcca agtcctcagg cttgatccaa cgaacggtct
    10081 ttttacccat tgggctcatg accacttccg cattgtattc gccttccata cggtgtttaa
    10141 agacttcaaa ctggagttga ccaacagctc ccagcatgta ctcgcctgtt tggtaatttt
    10201 tataaagctg aatagcacct tcttgcacca attgctcaat ccccttgtgg aaggattttt
    10261 gcttcataac attcttagca gaaactttca tgaaaatttc aggagtaaaa gttggcagtg
    10321 gttcaaattc aaacttgttt ttaccaactg tcaaggtatc cccaacttga taagtacctg
    10381 tatcgtaaac cccgataata tcacctgcca cggcattggt cacattctca cgactttccg
    10441 ccataaactg agtaacatta gacagtttag cccccttacc agtacgaggg agattaacac
    10501 tcatgccgcg ctcaaattcg ccagatacga tacggacaaa ggcaatacgg tcacggtgac
    10561 gagggtccat gttggcttgg attttaaaga caaagcctga gaaatccttg tcataaggat
    10621 ccacaatttc accgtctgtt ttcttgtgac catgtggttc tggagcaaac ttgaggaagg
    10681 tttcaaggaa ggtctgcaca ccaaagtttg tcagggctga accgaaaaag acaggcgtca
    10741 attctccagc cagaatagct tcctctgaaa actcattccc agcttcattt aaaagctcaa
    10801 tgtcatcctt gacttgatcg tagaaaggat tgctaccaaa gagtttgtcc ccgtcttcta
    10861 gactggcaaa acgctcatcc tctttgtaaa gctctaaacg ttggttatag aggtcataca
    10921 agccctcaaa ggctttcccc atcccaatag gccagttcat agggtagcta gcaatgccca
    10981 agatttcttc caattcttgc aagagatcca aaggctcacg accgtcacga tccaacttgt
    11041 tcataaaggt aaagactgga atgccacgat gtttcacaac ctcaaacaat ttcttggttt
    11101 gagcctcgat ccccttggca gagtccacga ccatgaccgc agcatccacc gccatcaagg
    11161 tacgataggt atcttctgag aagtcctcgt gccctggcgt gtctaagata ttcacgcgct
    11221 tgccgtcgta gtcaaattgc ataacagatg aagtaacaga aatcccacgt tgcttctcga
    11281 tatccatcca gtcagattta gcaaaagtcc ctgttttctt cccttttacc gtaccagcct
    11341 cacgaatctc acccccaaag tagagtaact gctcagtgat ggttgttttc cccgcgtccg
    11401 ggtgggagat aatggcaaag gtacgacgtt tcttaatttc ttcttgaata ttcataagtt
    11461 ctctttcttt gattctctat ttttcttgtt tcaatagctg agaatgattt ttacattgga
    11521 ttttaccatt cctttcaaca ctccattata tcggatttta gcattttttt caatttctat
    11581 ttcttttcac ttccccctcc cttatttata ggaaaatatg gtaaaataga acagactaaa
    11641 aatcatcatt tcacgaaagg atgcaagatg aaaattacgc aagaagaggt aacacacgtt
    11701 gccaatcttt caaaattaag attctctgaa gaagaaactg ctgcctttgc gaccaccttg
    11761 tctaagattg ttgacatggt tgaattgctg ggcgaagttg acacaactgg tgtcgcacct
    11821 actacgacta tggctgaccg caagactgta ctccgccctg atgtggtcga agaaggaaca
    11881 gaccgtgatc gcttgtttaa aaacgtacct gaacaagaca actactatat caaggtgcca
    11941 gctatcctag acgatggagg agatgcctaa tgacttttaa caataaaact attgaagagt
    12001 tgcacaatct ccttgtctct aaggaaattt ctgcaacaga attgacccaa gcaacacttg
    12061 aaaatatcaa gtctcgtgag gaagccctca attcatttgt caccatcgct gaggagcaag
    12121 ctcttgttca agctaaagcc attgatgaag ctggaattga tgctgacaat gtcctttcag
    12181 gaattccact tgctgttaag gataacatct ctacagacgg tattctcaca actgctgcct
    12241 caaaaatgct ctacaactat gagccaatct ttgatgcgac agctgttgcc aatgcaaaaa
    12301 ccaagggcat gattgtcgtt ggaaagacca acatggacga atttgctatg ggtggttcag
    12361 gtgaaacttc acactacgga gcaactaaaa acgcttggga ccacagcaag gttcctggtg
    12421 ggtcatcaag tggttctgcc gcagctgtag cctcaggaca agttcgcttg tcacttggtt
    12481 ctgatactgg tggttccatc cgccaacctg ctgccttcaa cggaatcgtt ggtctcaaac
    12541 caacctacgg aacagtttca cgtttcggtc tcattgcctt tggtagctca ttagaccaga
    12601 ttggaccttt tgctcctact gttaaggaaa atgccctctt actcaacgct attgccagcg
    12661 aagatgctaa agactctact tctgctcctg tccgcatcgc cgactttact tcaaaaatcg
    12721 gccaagacat caagggcatg aaaattgctt tgcctaagga atacctaggc gaaggaattg
    12781 atccagaggt taaggaaaca atcttaaacg cggccaaaca ctttgaaaaa ttgggtgcta
    12841 tcgtcgaaga agtcagcctt cctcactcta aatacggtgt tgccgtttat tacatcatcg
    12901 cttcatcaga agcttcatca aacttgcaac gttttgacgg tatccgttac ggctaccgcg
    12961 cagaagatgc gactaatctt gatgaaatct atgtaaacag ccgtagccaa ggttttggtg
    13021 aagaagtgaa gcgccgtatc atgctgggta ctttcagtct ttcatcaggt tactacgatg
    13081 cctactacaa gaaggctgga caggtccgta cacttatcat tcaagatttc gaaaaagtct
    13141 tcgcggatta tgatttgatt ttgggtccaa ctgctccaag tgttgcctat gacttgaatt
    13201 ctctcaacca tgacccagtt gccatgtact tagccgacct attgaccata cctgtaaact
    13261 tggcaggact gcctggaatt tcgattcctg ctggattctc tcaaggtcta cctgtcggac
    13321 tccaattgat tggtcccaag tactctgagg aaaccattta ccaagctgct gctgcttttg
    13381 aagcaacaac agactaccac aaacaacaac ccgtgatttt tggaggtgac aactaatgaa
    13441 ctttgaaaca gtcatcggac ttgaagtcca cgtagagctc aacaccaatt caaaaatctt
    13501 ctcacctact tctgcccact tcggaaatga tcaaaatgcc aacactaacg tgattgactg
    13561 gtctttccca ggagttctgc cagttctcaa taaaggggtt gttgatgccg gtatcaaggc
    13621 tgctcttgcc ctcaacatgg acatccacaa aaaaatgcac tttgaccgca agaactactt
    13681 ctaccctgat aatcccaaag cctaccaaat ttctcagttt gatgagccaa tcggttataa
    13741 cggctggatt gaagtcgagc tagaagacgg tacgaccaag aaaattggta tcgaacgcgc
    13801 ccacttagag gaagacgctg gtaaaaacac ccacggtaca gacggctact cttacgttga
    13861 ccttaaccgc caaggggtac ctttgattga gattgtatct gaagccgata tgcgttcgcc
    13921 agaggaggcc tatgcttatc tgacagcact caaggaagtt atccagtatg ctggcatttc
    13981 tgacgttaag atggaggaag gttcgatgcg tgtggatgcc aacatctccc ttcgtcctta
    14041 tggtcaagag aaattcggta ccaagactga attgaagaac ctcaactcct tctcaaacgt
    14101 tcgcaagggg cttgaatacg aagtccaacg ccaggctgaa attcttcgct caggtggtca
    14161 aatccgccaa gaaacacgcc gttacgatga agcgaataaa gcaaccatcc tcatgcgtgt
    14221 caaggaaggg gctgctgact accgctactt cccagaacca gacctacccc tctttgaaat
    14281 ttctgacgag tggattgagg aaatgcggac tgagttgcca gagtttccaa aagaacgtcg
    14341 tgcgcgttat gtatctgacc ttggtttatc agactacgat gctagtcagt tgactgctaa
    14401 taaagtcact tctgacttct ttgaaaaagc tgttgcccta ggtggtgatg ccaaacaagt
    14461 ctctaactgg ctccaagggg aagtcgctca gttcttgaat gctgaaggta aaacactgga
    14521 acaaatcgaa ttgacaccag aaaacttggt tgaaatgatt accatcatcg aagacggtac
    14581 tatttcatct aagattgcca agaaagtctt tgtccatcta gctaaaaatg gcggtggcgc
    14641 gcgtgaatac gtggaaaaag caggtatggt tcaaatttca gatccagcta tcttgatccc
    14701 aatcatccac caagtctttg ccgataacga agctgctgtt gccgacttca agtcaggcaa
    14761 acgtaacgcc gacaaggcct ttacaggatt ccttatgaag gcaaccaaag gccaagccaa
    14821 cccacaagtt gcccttaaac tacttgcaca ggaattggcg aagttgaaag aaaactagac
    14881 agaacaaaac cagccctaag gttggttttt tcttctctac caactcccaa taactatttt
    14941 ggctttattt ccagagtatt ttatggtaaa atgaagagta ataatattta ttaaagaggt
    15001 aaaaacatga ttgaagcaag taaattaaaa gctggtatga cctttgaaac agctgacggc
    15061 aaattgattc gcgttttgga agctagtcac cacaaaccag gtaaaggaaa cacgatcatg
    15121 cgtatgaaat tgcgtgatgt ccgtactggt tctacatttg acacaagcta ccgtccagag
    15181 gaaaaatttg aacaagctat tatcgagact gtcccagctc aatacttgta caaaatggat
    15241 gacacagcat acttcatgaa tacagaaact tacgaccaat acgaaatccc tgtagtcaat
    15301 gttgaaaacg aattgcttta catccttgaa aactctgatg tgaaaatcca attctacgga
    15361 actgaagtga tcggtgtcac cgttcctact actgttgagt tgacagttgc tgaaactcaa
    15421 ccatctatca aaggtgctac tgttacaggt tctggtaaac cagcaacgat ggaaactgga
    15481 cttgtcgtaa acgttccaga cttcatcgaa gcaggacaaa aactcgttat caacactgca
    15541 gaaggaactt acgtttctcg tgcctaatct ctagaaagag gtcattctat gggaattgaa
    15601 gaacaacttg gcgaaatcgt tatcgcccca cgtgtacttg aaaaaatcat tgctatcgct
    15661 actgcaaagg tagagggtgt tcactctttt tcaaacagat cagtgtctga taccctttca
    15721 aaactttcac tcggccgtgg catttatctt aaaaacgtgg acgaagaact cacagcagat
    15781 atctatctct accttgagta cggagtaaaa gttcctaagg tagcggttgc tatccagaaa
    15841 gctgtcaaag atgccgtccg taatatggct gatgtagaac tcgctgctat caatattcac
    15901 gttgcaggta tcgtcccaga taaaacacca aaaccagaat tgaaagatct atttgacgag
    15961 gacttcctca atgactagtc cactattaga atctagacgc caactccgta aatgcgcttt
    16021 tcaagctctc atgagccttg agttcggtac ggatgtcgaa actgcttgtc gtttcgccta
    16081 tactcatgat cgtgaagata cggatgtaca acttccagcc tttttgatag acctcgtttc
    16141 tggtgttcaa gctaaaaagg aagaactaga taagcaaatc actcagcatt taaaagcagg
    16201 ttggaccatt gaacgcttaa cgctcgtgga gagaaacctc cttcgcttgg gagtctttga
    16261 aatcacttca tttgacactc ctcagctggt tgctgttaat gaagctatcg agcttgcaaa
    16321 ggacttctcc gatcaaaaat ctgcccgttt tatcaatgga ctgctcagcc agtttgtaac
    16381 agaagaacaa taaaaagaaa aagtgtttga tagatatcaa acactttttc tttgcctccc
    16441 actatctaaa aaaatgataa tagatataat tgtaaacaaa aatccagata ggttttgcat
    16501 gattgagaaa gttaaaaaaa ctatggcaga gaatcgttaa tctcagattg tcggtagaac
    16561 gataaacaag ggcaaaaaag aaaccaatca gactataata taataaacta attggatctc
    16621 tgtgagatag tatcaaatgg ctaatcccaa agatgatagc agataggata acatccaaat
    16681 agtacttgga ctagggaaag aaggtattca taaaataccc tctatcaaga gtctcctcaa
    16741 aaacaggacc gatgattaca ggcaggacaa aagataagat agtcgataaa aaggttggtt
    16801 gtccatttga aaaaagcacg gtaaaatact catcatgaat attcctatga ttaatcaaat
    16861 gagcatagcg tgcccaaaaa ttaccgagaa tctgataaac cacataagtt gcaaataagt
    16921 agaagacaaa tgaccagttc cagctctttt tctcaaagat aaagagcatc tttttctttt
    16981 ttaacctcca aattaataga aggaaacttc ccactaatcc cattgttaaa ataagagaat
    17041 agacatcagc tcctaaccct aaaatgatcg tcacatacaa tccaattgtt tgtggtaaat
    17101 aggtagatag taaaataata agcaaaaata ttccaaattg tcttagtttt tttgtgtttc
    17161 tcatcgtact tttttgaaag attaccctgc tcggaagccg tacttccaag catctatata
    17221 agaattaagt gccccttgcc tcatataggg agcaaattct ctataatata accatctact
    17281 atatccatct tcccaaacag caagaccacc tgaagtttgc tccaagtcct cagttgaaag
    17341 aactgtaaat gtatttgtac ctgtcattgc aagtaccttc ttaaaatata gtg
//
LOCUS       DAVLMQ010000037        15994 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000037 DAVLMQ010000000
VERSION     DAVLMQ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.037"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            102..1379
                     /locus_tag="VXF95_001529"
     CDS             102..1379
                     /locus_tag="VXF95_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HEV1082059.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATPEIQAFALNGDEVIISPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKFLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            1455..2939
                     /locus_tag="VXF95_001530"
     CDS             1455..2939
                     /locus_tag="VXF95_001530"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HEV1082060.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKDGVSKIQELQMTTQTGDNTHVIAIDGNFDDAQTNVKHMFNDVALCEKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGDKINFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVCELDS
                     YIEDPHTAVASAVYKKYQSATGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPVRHKTTVAAADMQAAVEAYLGL"
     gene            3000..4280
                     /locus_tag="VXF95_001531"
     CDS             3000..4280
                     /locus_tag="VXF95_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1082061.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTIVSRLVGLVILWSQLKLPYEKPTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVATA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            4284..4904
                     /locus_tag="VXF95_001532"
     CDS             4284..4904
                     /locus_tag="VXF95_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HEV1082062.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            5070..6212
                     /locus_tag="VXF95_001533"
     CDS             5070..6212
                     /locus_tag="VXF95_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HEV1082063.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASSSEVTKTV
                     IASEEVAPSTGTSVPEEQTAETTRPVEEATPQETTPAEKQETQASPQAASAVEATTTS
                     SEAKEVASSNGATAAVSTYQPEETKVISTTYEAPAAPDYAGLAVAKSENAGLQPQTAA
                     FKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVAERSELGDKIAEYAIQNMASRGI
                     SYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG"
     gene            6618..6956
                     /locus_tag="VXF95_001534"
     CDS             6618..6956
                     /locus_tag="VXF95_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1082064.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRHFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            6967..7325
                     /locus_tag="VXF95_001535"
                     /pseudo
     CDS             6967..7325
                     /locus_tag="VXF95_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861952.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
     gene            7432..8049
                     /gene="pcp"
                     /locus_tag="VXF95_001536"
                     /pseudo
     CDS             7432..8049
                     /gene="pcp"
                     /locus_tag="VXF95_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
     gene            complement(8077..8934)
                     /locus_tag="VXF95_001537"
     CDS             complement(8077..8934)
                     /locus_tag="VXF95_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HEV1082065.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSSFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQRFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            9064..10206
                     /gene="tgt"
                     /locus_tag="VXF95_001538"
     CDS             9064..10206
                     /gene="tgt"
                     /locus_tag="VXF95_001538"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HEV1082066.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMFLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREYFVEKYGYNKSGRNF"
     gene            10304..12121
                     /locus_tag="VXF95_001539"
     CDS             10304..12121
                     /locus_tag="VXF95_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HEV1082067.1"
                     /translation="MRIKWFSLVRITGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNHEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     ASVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGIVFLLSAVAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILVAGTGILTIIVCTVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            12274..13425
                     /gene="nagA"
                     /locus_tag="VXF95_001540"
     CDS             12274..13425
                     /gene="nagA"
                     /locus_tag="VXF95_001540"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HEV1082068.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            13588..14646
                     /locus_tag="VXF95_001541"
     CDS             13588..14646
                     /locus_tag="VXF95_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1082069.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPEKAIKEIYDLTDGRGVDVAIEAVGIPATFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            complement(14695..15950)
                     /locus_tag="VXF95_001542"
     CDS             complement(join(14695..14732,14732..15950))
                     /locus_tag="VXF95_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436265.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1082070.1"
                     /translation="MEQLHFITKLLDIKDPNIKILDIINMDTHKEIIAKLDYEAPSCP
                     DCGSLMKKYDFQKPSKIPYLETTGMPSRILLRKRRFKCYHCSKMMVAETPLVKKNHQI
                     PRIINQKIAQKLIEKISMTDIAHQLAISTSTVIRKLNDFHFEHDFSRLPKIMSWDEYA
                     FTKGKMSFIAQDFDNLNIITVLEGRTQAVIRNHFLRYDRAVRCQVKIITMDMFSPYYD
                     LAKQLFPCAKIVLDRFHIIQHLSRAMSRFRVQIMNQFERKSHEYKAIKRYWKLIQQDS
                     RKLSDKRFYRPTFRMHLTNKEILDKILSYSEDLKHHYQLYQLLLFHFQNKEPEKFFGL
                     IEDNLKQVHPLFQTVFKTFLKDKEKIVNALQLHYSNAKLEATNNLIKLIKRNAFGFRN
                     FENFKKRIFIALNIKKERTNFVLSRA"
BASE COUNT         4689 a         2796 c         3662 g         4847 t
ORIGIN      
        1 tagtgttagg aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata
       61 gttattcaaa ttttatttag attaagaaag tgtaggggag tatgtcttgt tctatcgatt
      121 tattaaaaca tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg
      181 agttggagta tcctgttgca agtttagaag gggatgctac agatgttgaa gttataaagg
      241 atctatttca ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg
      301 gcaatctgat ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct
      361 atacaacgat tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt
      421 tcaataatta tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg
      481 gctgtggtat ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct
      541 atcagatgtt gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc
      601 atttccctga atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa
      661 ccaactactt acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat
      721 ttgcaaactc tgagttttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct
      781 gggaagaatc tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta
      841 atgatgaagc tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg
      901 atgggcagac ctattatttt tatcctattc aggctgggga ctatttggct acgcctgaaa
      961 tccaagcatt tgctctgaat ggggatgagg ttattatttc cccccaagag aaggattttg
     1021 aaactcatcg tagttaccag taccaagact taacgactcg aggaacagtt gagtttcgta
     1081 gtgtgtgtac acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat
     1141 tggttaattt agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg
     1201 gttatgatta caagttttta aggagacaat tttctaagaa aaatcttaca gatgaggaag
     1261 aaactacgat tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg
     1321 tgagaaataa ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat
     1381 ttctcttata aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata
     1441 aaggatagag agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa
     1501 ctgccagcca agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta
     1561 cttatccaaa ggtagatttg gactttgaca aattgaaaga tgcttcttat caggaagttg
     1621 ctaagctagt tttgtcagca tttttagatg actttacagc tgaggagttg gactactgta
     1681 tcaacaatgc ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag
     1741 atgggcaata caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct
     1801 tgtctatttt gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga
     1861 ttgttatctt gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg
     1921 atgtgcctgg tactgagatt atcgtctttt atccaaagga tggtgtcagc aagattcaag
     1981 agttacaaat gaccactcaa actggcgaca atactcatgt tattgctatt gatggtaact
     2041 ttgacgatgc gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt tgtgaaaaat
     2101 tgactaccaa caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc
     2161 cacagattgt ttattatgtt tatgcctatg ctcagttggt caagactggt gagatcgtgg
     2221 ctggtgataa gattaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct
     2281 tttatgccaa acaaattggt ttgccagttg gtaaattaat ctgtgcttca aatgacaata
     2341 atgtcttgac agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa
     2401 caaccagccc atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc
     2461 ttttgggaaa taatgctgaa aagacagctg aacttatgaa tgccttgaac acgcaaggac
     2521 aatataagtt gacagacttt gatgcagaga ttttggacct ctttgcagct gaatatgcga
     2581 ctgaggaaga aacggcagca gagatcaagc gtgtttgtga gttagattct tatatcgagg
     2641 accctcatac agctgttgct tcagcagttt ataaaaaata ccaatcggcc actggagatg
     2701 taactaagac agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag
     2761 aagctgtaac tggaaaagca ggtttaacag actttgaagc cttggctcaa ttacatgaaa
     2821 tctcaggcgt tgcagtgcca ccagcagttg atgggcttga aatagctcct gttcgtcaca
     2881 agacaactgt agcggctgct gatatgcaag cagcggttga ggcttattta ggactttaag
     2941 atagagggag taaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat
     3001 tgtttaagaa aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt
     3061 tgcagatgct aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta
     3121 tttcaggggt ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc
     3181 tgggagctgc tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt
     3241 tggcctatca tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat
     3301 ttttgtccat cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag
     3361 ctgagagtgg tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa
     3421 tgactagtct gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta
     3481 gttttttatc caatgccttg aatattcttt tttcaagtct agctattttt gttctggata
     3541 tggggatagc tggtgttgct tgggggacaa ttgtgtctcg tttggttggt cttgtgattt
     3601 tgtggtcaca attaaaactg ccttatgaga agccaacttt tggtttagat aaggaactgt
     3661 tgaccttggc tttaccagca gctggagagc gacttatgat gagggctgga gatgtagtga
     3721 tcattgcctt ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag
     3781 tcttgaccca gtttaactat atgcctgcct ttggcgtcgc tacggcaacg gtcatgctgt
     3841 tggcccgagc agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct
     3901 tttggctttc tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac
     3961 cattaactca tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac
     4021 tgttttcact acttgggacc cctatgacga caggaacagt catctatacg gcagtctggc
     4081 agggattagg aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc
     4141 gcattgggac aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg
     4201 cagggtctct cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct
     4261 atatgagctt gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga
     4321 ctttattgga ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt
     4381 ctattcctta tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaaaatt
     4441 tgcttgtgcg ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg
     4501 cccagagtct ggctgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc
     4561 tagcttgggc agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg
     4621 cttttaccat tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc
     4681 agagtggctt tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc
     4741 agttgaattc tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc
     4801 agaatagtgg gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga
     4861 ttcaagcgtt agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca
     4921 gttttgtgac agagacctaa caaactattt caagtaacct agtttgttac aaggagtaga
     4981 cagttctgtt aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac
     5041 aggtactcat ttgaaaggaa tttgaaagaa tgaagaaaag aatgttatta gcgtcaacag
     5101 tagccttgtc atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac
     5161 gtagtgttga gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg
     5221 tacagtatgg tgatactttg agcaccattg cagaagcctt gggtgtagat gtcacagtgc
     5281 ttgcgaatct gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa
     5341 cgactgtcaa tgaagcagaa gaagtaacag aagttgaaat ccaaacacct caagcagact
     5401 ctagtgaaga agtgacaact gcgacagcag atttgaccac taatcaagtg accgttgatg
     5461 atcaaactgt tcaggttgca gacctttctc aaccgattgc agaagctcca aaagaagtag
     5521 catcaagttc agaagttaca aagacagtga ttgcttctga agaagtggca ccatctacgg
     5581 gcacttctgt cccagaggag caaacggccg aaacaactcg cccagttgaa gaagcaactc
     5641 ctcaggaaac gactccagct gagaagcagg aaacacaagc aagccctcaa gctgcatcag
     5701 cagtggaagc aactacaaca agttcagaag caaaagaagt agcatcatca aatggagcta
     5761 cagcagcagt ttctacttat caaccagaag aaacgaaagt aatttcaaca acttacgagg
     5821 caccagctgc gcccgattat gctggacttg cagtagcaaa atctgaaaat gcaggtcttc
     5881 aaccacaaac agctgccttt aaagaagaaa ttgctaactt gtttggcatt acatccttta
     5941 gtggttatcg tccaggagac agtggagatc acggaaaagg tttggctatc gactttatgg
     6001 tagcagaacg ttcagaatta ggggataaga ttgcggaata tgctattcaa aacatggcca
     6061 gccgtggcat tagttacatc atctggaaac aacgtttcta tgctccattc gatagcaaat
     6121 atgggccagc taacacttgg aacccaatgc cagaccgtgg tagtgtgaca gaaaatcact
     6181 atgatcacgt tcacgtttca atgaatggat aaacccgact tgataacatc attttgacga
     6241 atgagatcta gctttcgtga tggaaagcga ttctcgttcg ttttttcttt gtcatactct
     6301 tcgaaaatct cttcaaacca cgtcagtttt atatgaaacc tcaaagctgt gctttgagca
     6361 acctgcgact agcttcctag tttgctcttt gattttcatt gagtatcaat ttgaatggaa
     6421 aatggaaagt tattatcttg taataatcca agcaacattc ttgcaatcta ttttacttta
     6481 tatcacaatt gattggtcaa ctattgataa gtcaatggat aggaggaaga aatgatagag
     6541 attcaagatt tactgtatca actccgcttg tctgagcaag cgagtacgca attgtttgaa
     6601 aaaggcttgg gattagtttg acacggtatc agattttact gtttttgctg gagcattctc
     6661 cttgtaacca aatggcggtt caggagcgtt tgaaaattga tcaggctgct ttgacacggc
     6721 atttcaagat tttggaaacg gaaggtttgg tggagcgtca tcgtaatcct gaaaatcagc
     6781 gggaagtgtt ggtagaggct gcgaagtatg ccaaggagca gttagtggtg aatccccctc
     6841 tgcaacatat caaggttaag gaagagatgg aaagtatctt aacagagttt gagagaacag
     6901 aactcagccg tttattaaat aaattggttt tgggtattga aaatatagaa atttaaggag
     6961 aaatagatgt caattatttt aacaacgatc gttgctttgg agcattttta tattttttat
     7021 ttggaaagta ttgccacgca atcagatgcg actagtcgtg tatttaatat ggaaaaggaa
     7081 gaattggctc atccgtcagt aagttcattg ttcaaaaatc aaggaattta taaggctctg
     7141 ctaggagtct ttctcttgta tgtcatttat ttctcacaga atttagaaat tgtgactatt
     7201 tttgtcttat ttgtgattgg tgctgcgact tacggctctt taacagcgga taaaaaatta
     7261 ttttgaagca aggtggatca gctattttgg ccttgattag tattttactc tttaaataca
     7321 cttgaaggtt gattctaatc tcgctaatcc tttttaatcc agaataaggg aaatatgtta
     7381 tacttgtttt taagaaaaaa gtctcattga attggttttg aggagttaga aatgaaagta
     7441 ttagtgacag gttttgagcc cttttgaggc cattaaaggt ttaccagctg aaatccatgg
     7501 tgctgaggtc cgttagctag aggtgccgac agtttttcac aaatctgctc aagtattgga
     7561 agaagagatg aatcgttatc aacctgactt tgtcctttgt attgggcaag ctggtggaag
     7621 aactagtttg acacctgaac gagtggccat taatcaagac gatgcacgca tttctgataa
     7681 cgaagataat caaccgattg accgtcccat tcgcccagat ggtgcttcgg cctactttag
     7741 tagtttgccg attaaagcga tggttcaagc tataaaaaag agggcttacc ggcctctgtt
     7801 tccaatacgg cagggacttt tgtctgcagc catttgatgt atcaggctct ctatttggta
     7861 gaaaagaaat ttccatatgt taaggcaggt tttatgcata ttccttatat gatggaacag
     7921 gtggtgaaca gacagactat tccagctatg agtttagtgg atattcggcg agggatagaa
     7981 gcagcaatcg gcgctatgat agaacatgga gatcaggaac tcaagttggt aggcggagaa
     8041 actcattgat agaaaaaagc ttgagtggaa aaaccttcaa gcttttggac gttttcgagc
     8101 caatactgct cggtaaaaca taattttagt gcattggata taaggtagga gtgaaaaact
     8161 agcaatgcca aaggtaatcc aattgaggaa gtaccaagga agaagctgta aatctaggac
     8221 aaagcgctgg aacttgtagc ccttcataaa ggaacggcta gtttttagga ttcgtcttgg
     8281 tgggacctgt cctaggtcta gactataaca gagaagaaat tccacctgtg aataggcata
     8341 atactgtgga atatagagga tatttcctac aatgatcaag atgagacttg caagaaagta
     8401 gagtccaaag accatgagga aacgctcggt ttcaactgat gagagatcta gatttggaaa
     8461 ctcaggatgt agggtgacga attttttggc taaaaagcta ctataaaaga ggaggtaaat
     8521 cccaagtaaa ttagggatac tccataaaaa gagatagaaa cgtttgagaa gtagggtcaa
     8581 aaaggtttga gaaaagcgct cctcatcaaa gagagctagg ctgtttttta cagatggctc
     8641 cgttttagaa tctttcatga gtgtcagtgt tgcatagacg gaactggtca aaagaatagt
     8701 cccgataaag gagactagta gaggaaagag gtaggtttga agtatttggc caagtatgct
     8761 gaaaaatggc tgttctaaaa cagtcccgtg gatccgagat aagggattaa gaaaactaga
     8821 taagatgacc agcatactgg gaaggatata gaggagaaag agacgggggg tgtcagcctg
     8881 aaaatgtttt gactcctgac gaattgtttt taaatcaatt tttggatagt tcattctctt
     8941 attataccat agttcttata catagttcgt gacagttcct actttttttg ataaaatcat
     9001 acagtgtgtc cttgggcaca ctgtatgaac tgggactgtc tttcccagct tcggaggtaa
     9061 aaaatgtcag attcaccaat caaatatcgt ttgattaaga aagaaaaaca cacaggagct
     9121 cgtctgggag aaatcatcac tccccacggt acctttccga cacctatgtt tatgccagtt
     9181 gggacacaag ccactgtcaa aactcagtca cctgaagaat tgaaggagat gggttcggga
     9241 attatcctat caaacaccta tcatctctgg cttcgccctg gagatgaact cattgcacgc
     9301 gctggtggtc tccacaagtt catgaattgg gaccagccta tcttgacaga tagtggtggt
     9361 tttcaggttt attctttagc agatagccgt aatatcacag aagaaggagt aacctttaaa
     9421 aatcatctaa atggttctaa gatgttccta tccccagaaa aagccatctc tattcagaat
     9481 aatctgggtt cagacatcat gatgtccttt gatgaatgtc ctcagtttta tcaaccttat
     9541 gactacgtta agaaatcgat cgagcgtacc agccgttggg ctgagcgtgg tttgaaggct
     9601 caccgtcgtc cacatgacca aggtttgttt ggaattgtgc aaggtgcagg atttgaagac
     9661 cttcgccgcc aatcagctca tgatcttgtc agcatggatt tctcaggcta ctctatcggt
     9721 ggtttggcag tgggagaaac ccatgaagag atgaatgcgg tcttggactt tacaactcaa
     9781 ctgctgcctg aaaataaacc tcgttatctg atgggtgtgg gagcgccaga tagcttgatc
     9841 gatggggtca ttcgtggggt ggatatgttt gactgtgtct taccgactcg aattgctcgt
     9901 aacgggactt gtatgaccag tcaaggacgt ttggttgtga aaaatgccca gtttgctgag
     9961 gactttacgc cactggatcc tgagtgtgac tgctacacat gtaataacta tacacgcgct
    10021 taccttcgtc acctgctcaa ggctgatgaa acctttggta tccgcttgac tagctaccac
    10081 aatctttact tcttgcttaa cctgatgaag caagtgcgac aagccatcat ggatgacaat
    10141 ctcttggaat tccgtgagta ttttgtggaa aaatatggct ataataagtc aggacgtaat
    10201 ttctaaaatg gaattgatat aaaaaaatcc taagttttct cttaggattt ttcttctttt
    10261 tttgatagaa taaagtgtac aatgaaagga agaataaact cgtatgcgca ttaaatggtt
    10321 ttccttggtt aggattacag gtttactttt ggtactcttg tatcacttct ttcagacgat
    10381 ctttcctgga ggatttttcg gggtagatgt ctttttcaca ttttcaggtt tcctgattac
    10441 agctctactc attgaagaat tttctaaaaa ccatgagatt gatttgatag gattttttag
    10501 aagacgcttt tatcggattg tgccacctgt ggttttgatg gtcttggtga ccatgccttt
    10561 tactttcttg gttcgccaag actatgttgc tggaattggt ggccagattg cgagcgtctt
    10621 aggctttatg accaacttct atgaactcct aacaggtggg agttatgaat ctcagttcat
    10681 tcctcatttg tttgttcata attggagttt ggcagttgag gttcactact atattctttg
    10741 gggattggca gtttggttct tatccaaaca agctaaatca aatggtcagt tgaaggggat
    10801 agtctttctc ttatctgctg ttgccttctt gatcagtttc ttctccatgt ttattggtag
    10861 ttttctagtg acctcttatt cctctgttta tttctccagt ttaactcatg tctatccatt
    10921 ctttttggga agtatgttag caactattgt aggtgttcgt cagacgactt ccctcgtcaa
    10981 gcagttggat aaaatctggg atttacgaaa gactttggta gtttttggag gaggctttgg
    11041 tttcctagtt cttttgactt tctttgtcaa attcacttat ctttttgcct atcttatcgg
    11101 cttcttgctt gccagtcttg cagctcttgc catgattctg gcggcgcgtg tcttacatga
    11161 aaagacacat catatacagg agccgaagat tatcagcttt ttagcggata ctagctatgc
    11221 ggtttatctt ttccattggc ctttctatat cattttctca cagttgacat caaatcttct
    11281 tgctgtatta ctgactctga tttgttctta tggctttgcc agtctgtcat tctatgtatt
    11341 ggaaccttgg attgcaggca agaacacacc tattttacaa actcttcgtc ccctgcctta
    11401 tattcacgca attcttgtag caggtacagg aatcttgacc atcattgtct gcacggtgac
    11461 cttgttggca ccacaagtgg gagcgtttga gacagacttg actgtcaatg gcttgaagca
    11521 agctgcaaca aatattggcc agaccaaggt gatggcagaa cgggcagatg caaacagttt
    11581 gggaattgct gatggcacta tgttaattgg tgactcagtg gctttaaggg caaatacagc
    11641 actacagaca gctcttcctg gagcacagat taacgcgcag gtcagcgtaa caaccaagac
    11701 cgcaaatgaa atcatgctaa ataatagcca gaataaattt ttacctaaga cggtggtcat
    11761 tgcgactggg gtaaataatc ctgagaatta caaggatgac tgggacagta tcgtgaaaaa
    11821 tcttcctaag ggacaccata tgattttggt gactccttat gagggagata agacaaaaga
    11881 gacctatgcc atcgttgaga aggctgctgc ctatatgaga gaattggcag agaagacacc
    11941 ttacattacg atagcagatt ggaatcaagt tgcgaaagag catccagaaa tttgggcagg
    12001 aacagaccag gttcatttcg ggagtgagag tagcactatc gaagcaggag caaaattgta
    12061 tgcagatacg attgccacag ctttgcagac agctcaagac aagccggtta aatcaaaata
    12121 acttgtatta aaaaagagaa gagttggaga aatccagctc ttttaaaata tctccaaaaa
    12181 ataggtctat accatttaca aataaaaaag aaaggtttat aatgtaattg acataataaa
    12241 ttgcagaatc aatcttttaa ggaggttaac attatgccta actatattaa agcggatcag
    12301 tttttctacc cacacggagt tcgtcgaggt ggttacttgg aacttgtgga cggcaagttt
    12361 gggaaacatg tagagcagat tcctgaaggg gctgaggtga ttgactatac aggttatagc
    12421 attgccccag gtcttgtgga tactcatatt catggatatg caggtgtaga tgtgatggac
    12481 aacaacattg aaggtacatt gcatactatg agtgaaggac ttcttagtac cggtgttacc
    12541 agtttcttac ccacaacttt aacagccact tatgagcaat tgcttgcagt cactgaaaat
    12601 cttggaaacc attataaaga agcaacaggt gctaagattc gtgggattta ttatgaaggt
    12661 ccatatttca cagaaacttt taagggggca caaaatccaa cttatatgag agacccgggt
    12721 gttgaggagt ttcattcttg gcaaaaagcg gcaaatggct tgcttaataa aattgccctt
    12781 gcaccagaac gtgatggggt ggaagacttt gttcgtacag ttacgggcga aggtgtgacg
    12841 gttgctcttg gacattcaaa cgcgactttt gatgaagcca aaaaagcagt cgatgctgga
    12901 gcgagtgttt gggtgcatgc ctacaatgga atgcgtgggt tgactcaccg tgaattgggt
    12961 atggttggag ccatgtacca attgccacat acctatgcag agttgatctg tgatggtcac
    13021 cacgtagatc caaaggcttg cgaaattctt atcaaacaaa aaggaacaga aaacatcgct
    13081 cttatcacag actgtatgac agctggggga ttggaagacg gagattatat gttgggagaa
    13141 ttcccagttg tcgttgcaaa tggaactgca cgcctcaaat cgacaggtaa cttggcaggt
    13201 tctatcctca aactcaaaga tggtttgaag aatgtggtcg aatggggaat tgcgaatccg
    13261 catgaagcag tcatgatggc cagcttcaac ccagctaaat ccgttcacat cgatgacgtc
    13321 tgtggccaaa tccgtgaagg ctacgacgct gacttcatcg tattagataa agatttggaa
    13381 ttggtagcaa cctacctaga tggcgtaaaa cgttatcaag cataagagag aaagcagaag
    13441 ttagagacta acttctgctt ttttatgcag ggtactttac tggtaaataa aaagttaaaa
    13501 aaatcacaaa aaaagcttga agaaacaaag aaaaaggctt acaattgaac tataaatatt
    13561 acaaataaaa aaacggagga gtgctttatg aaagcctata cttatgttaa accaggactt
    13621 gcttcttttg ttgatgtaga caaaccagtt attcgcaagc caacagacgc tattgtgcgt
    13681 attgtaaaaa ccactatttg tggaacagac ctccatatta tcaaagggga tgttcctact
    13741 tgccaaagtg gtaccattct tggccacgaa gggattggga ttgttgaaga agttggggaa
    13801 ggagtttcca acttcaaaaa aggtgacaag gtcttgattt cttgcgtctg tgcctgtggt
    13861 aaatgctact actgtaaaaa aggaatttat gctcactgtg aagacgaagg gggctggatt
    13921 ttcggtcact tgattgatgg tatgcaggct gaatatctac gtgtccctca tgcagataat
    13981 actctttacc atactccaga agacttgtca gatgaagctt tggttatgct gtcagacatt
    14041 ctgcctactg gatatgaaat tggtgtctta aaagggaaag tagaacctgg ttgcagcgta
    14101 gccattattg gttcaggtcc agttggattg gctgctcttt taacagccca attctattca
    14161 ccagctaaat tgattatggt agacctagac gataaccgct tggaaactgc cctatcattc
    14221 ggtgcgactc ataaggttaa ttcttcagac cctgaaaaag ccattaaaga aatttatgat
    14281 ttgacagatg gtcgtggtgt ggatgtcgct atcgaagctg ttggtattcc tgcaacattt
    14341 gatttctgtc aaaagattat cggtgtagac ggaacggttg ccaactgtgg tgtgcatggt
    14401 aaaccagttg aattcgattt agataaactt tggattcgca acatcaatgt aacaactggt
    14461 ttggtatcta caaatacgac tccacaattg ttgaaagcgc ttgaaagtca taagattgaa
    14521 ccagaaaaat tggtaactca ctatttcaaa ctcagtgaaa ttgaaaaagc ctacgaagtc
    14581 ttcagtaagg cagcagacca ccatgccatt aaggtcatta tcgaaaacga tatctcagaa
    14641 gcctaagtag taaaaatatt tggctctttg tcaactgtag tgggttgaag tcagctaagc
    14701 tcgagaaagg acaaaattcg tcctttcttt ttgatgttca gagcgataaa aatccgtttt
    14761 ttgaagtttt caaagttccg aaaaccaaag gcattgcgct tgataagttt gatgagatta
    14821 ttggtcgctt ccaatttggc gttagaatag tgtagttgaa gggcgttgac gattttctct
    14881 ttgtccttta gaaaggtttt aaagacagtc tgaaaaagag gatgaacctg cttaagattg
    14941 tcctcaatga gtccgaaaaa tttctccggt tccttattct gaaagtgaaa aagtaagagt
    15001 tgatagagct gatagtggtg tttcaagtct tctgaatagc ttaaaatctt gtcaagaatt
    15061 tctttatttg ttaagtgcat gcgaaaagta gggcgataaa aacgtttatc gctcaattta
    15121 cgactatcct gttggatgag tttccagtaa cgtttgatag ccttgtattc atgagatttt
    15181 cgttcaaact gattcataat ttgaacacga aaacgactca tggcacggct gagatgttgg
    15241 ataatatgga aacgatctag aacgatttta gcacacggaa aaagctgttt agccaagtca
    15301 tagtaaggac taaacatatc catcgtaatg attttcactt gacaacgaac ggctctatcg
    15361 tagcgaagaa agtgatttcg gatgacagct tgtgttctgc cttcaagaac agtgataata
    15421 ttaagattat caaaatcttg cgcaatgaaa ctcatctttc ccttagtgaa ggcatactca
    15481 tcccaagaca taatctttgg aagccgagaa aaatcatgct caaagtgaaa gtcattgagc
    15541 ttgcgaatga cagttgaagt tgaaatggcc agctgatggg caatatcagt catagaaatt
    15601 ttttcaatta acttttgagc aattttttgg ttgatgatac gagggatttg gtgatttttc
    15661 tttaccaggg gagtctcagc aaccatcatt tttgaacagt gatagcactt gaaacggcgt
    15721 tttctaagga gaattctaga aggcatacca gttgtttcga ggtaagggat cttagacggt
    15781 ttttgaaagt catatttctt cattagactt ccacaatcag ggcaagatgg agcctcataa
    15841 tccagcttag cgataatttc tttgtgggta tccatattga tgatatctag aatcttgatg
    15901 tttgggtctt taatatcgag cagttttgtg ataaaatgta attgttccat atgaatcttt
    15961 ctaatgatgg ttttgtcgct tttcattata ggtc
//
LOCUS       DAVLMQ010000038        15615 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000038 DAVLMQ010000000
VERSION     DAVLMQ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15615
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.038"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            197..292
                     /locus_tag="VXF95_001543"
                     /pseudo
     CDS             197..292
                     /locus_tag="VXF95_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(545..1165)
                     /locus_tag="VXF95_001544"
     CDS             complement(545..1165)
                     /locus_tag="VXF95_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1082071.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPGSIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1165..1647)
                     /locus_tag="VXF95_001545"
     CDS             complement(1165..1647)
                     /locus_tag="VXF95_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HEV1082072.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYHIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1647..2489)
                     /locus_tag="VXF95_001546"
     CDS             complement(1647..2489)
                     /locus_tag="VXF95_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HEV1082073.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2584..3384)
                     /locus_tag="VXF95_001547"
     CDS             complement(2584..3384)
                     /locus_tag="VXF95_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HEV1082074.1"
                     /translation="MRKQIHPLILFSFLGIMMFILIINRPLNDSQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSAQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3528..4907
                     /gene="glmU"
                     /locus_tag="VXF95_001548"
     CDS             3528..4907
                     /gene="glmU"
                     /locus_tag="VXF95_001548"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HEV1082075.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILEGLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNERLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIAPEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4917..5462
                     /locus_tag="VXF95_001549"
     CDS             4917..5462
                     /locus_tag="VXF95_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1082076.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELKKK"
     gene            5474..5788
                     /locus_tag="VXF95_001550"
     CDS             5474..5788
                     /locus_tag="VXF95_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HEV1082077.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKNHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5805..6497
                     /locus_tag="VXF95_001551"
     CDS             5805..6497
                     /locus_tag="VXF95_001551"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HEV1082078.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVCGNTYHTGTIASHEVV
                     LVESGIGKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6574..7065
                     /gene="rocS"
                     /locus_tag="VXF95_001552"
     CDS             6574..7065
                     /gene="rocS"
                     /locus_tag="VXF95_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HEV1082079.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7163..7753
                     /locus_tag="VXF95_001553"
     CDS             7163..7753
                     /locus_tag="VXF95_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HEV1082080.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIDYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7762..9525
                     /locus_tag="VXF95_001554"
     CDS             7762..9525
                     /locus_tag="VXF95_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HEV1082081.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDKYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVITCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQENPEYTDLLLKKALEFFEF"
     gene            9739..10254
                     /locus_tag="VXF95_001555"
                     /pseudo
     CDS             9739..10254
                     /locus_tag="VXF95_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            10424..10624
                     /locus_tag="VXF95_001556"
     CDS             10424..10624
                     /locus_tag="VXF95_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082082.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDPK
                     IDATKAVLLDAQKVPEDSALTE"
     gene            10649..11065
                     /locus_tag="VXF95_001557"
     CDS             10649..11065
                     /locus_tag="VXF95_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082083.1"
                     /translation="MKAALDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETN
                     SVPAGVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKA
                     QNLLQETLDFVKEENGLAETETKLVEELKAILDKLK"
     gene            11296..12003
                     /gene="ccdA2"
                     /locus_tag="VXF95_001558"
     CDS             11296..12003
                     /gene="ccdA2"
                     /locus_tag="VXF95_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HEV1082084.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            12014..12571
                     /gene="sdbB"
                     /locus_tag="VXF95_001559"
     CDS             12014..12571
                     /gene="sdbB"
                     /locus_tag="VXF95_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HEV1082085.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDAPDFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAEAAFKEMN"
     gene            12945..14336
                     /locus_tag="VXF95_001560"
     CDS             12945..14336
                     /locus_tag="VXF95_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HEV1082086.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIAFPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIMAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLIMLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            14479..15396
                     /gene="adcAII"
                     /locus_tag="VXF95_001561"
     CDS             14479..15396
                     /gene="adcAII"
                     /locus_tag="VXF95_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HEV1082087.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDADVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSILAEELK"
     gene            15404..>15615
                     /locus_tag="VXF95_001562"
     CDS             15404..>15615
                     /locus_tag="VXF95_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1082088.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRHQAGQVKKESNRVSYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
BASE COUNT         4837 a         2742 c         3302 g         4734 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat tttttaactt gatactcagt gaaaagcaaa
       61 gattaaacta ggaagctagc tgtaggctgc tcaaagaaca gctttgaggt tgcagataaa
      121 acttgtgagg taaccaacat atataatgtg aagctgacgt ggtttgaata gattttagaa
      181 gggtatgagt ctggaagttt taatggataa tgcaagattc catagaatgg gtaagctaga
      241 gttcttatgt gaagagtttg ggcataaact tttacctttt cctccctact catcttagta
      301 tagaaaagtg aatctaaaat agtacataac tgcttctaaa acattcttat aaattgattt
      361 aaattctcaa atcatattat tcagttctta tttcattttg ctctacaatc ctgttgagaa
      421 gacacgtgtt catatcaaaa aggtattggc aagttgcaat acctttttac aaggttcttt
      481 tgtcttattt ttgtttcaac tgactatatc tcctatggtt ctagttcaga aggctaggct
      541 ataattatga ttgataagaa gtatcattcc aagtattgag agtgaatgtt tcaaaatcat
      601 gggtttctat aatggtcagg ctggcatttg ctagaccgcc atctttacga agaagtggtt
      661 ctttatagcc taggagagta cgaagactgg cagtaagatt ggcgccgtgt ccgacaatta
      721 gaatacgctc agctggacta tcttttaatg atttgataaa ttggatggtc cgctgagttg
      781 tactatagag ggattcggct ccgaacattc gagtgtcaaa ttgagcaaga tttgaacgaa
      841 aagcctggat ttgttgcggg taaatagctt ccagggttgc aattttcaaa ccttctaact
      901 tcccaagttg ccattcacgg agattaggaa cgatttctaa agaacagggg gtatggagtt
      961 gactttggat aatctcagca gatttgaccg ctcgaggtaa atcacttgaa taaatctgat
     1021 caaaaggaat ttccttgaga tactggccaa gtcgttttag ggtttcaatg gatccaggaa
     1081 gaagaggaga atcaccgcta gcaccttgaa aacgaccttc ttggttccag agggtacgac
     1141 cgtggcggac aaagtagagt ttcattactt gatgtcctcc aaaatatcta caaagtctgc
     1201 ctttacaaag ctagccaagt cttgtggcgc gacgataatg ctgtgtccga cttcgcctgc
     1261 agagacaatc attcgatcca aatctagagc aattttatcg ataaaaatgt gataattgtg
     1321 tttctgacga attccgacag gattattggc tccatgaatg taaccagttg ttttttctaa
     1381 gtccttttgt ggaatcatgc tcactttttt attgccagaa attttagcta gtttcttttc
     1441 agacaagtgc tgagtgatag ggacaattcc gataatcggt ccggtcttgt ctcccaaaag
     1501 cgccaaggtt ttgaaaatct gatctcgttc ataaccttga ggaagctctc cttctagggc
     1561 attgatttga atcccctgat gagggatagc tgctttagat aggatttgtt ccaccaatgt
     1621 ttttttgatt ttaacttttt ttgccattat ttatatttat cctccaattg actcatccaa
     1681 ataccaagcc agattcccag cgcaaagaag aaggcgatga tgacataacc gacaagtgaa
     1741 agtcctgtgt attggatact ttcagcgttt cctgcatttg gaattaagat caaaagggta
     1801 cttgatagga cgataccgat gatgaaatga tagacgcgtg agtggtagtt gtttaaggca
     1861 taatccatca attttgaaaa aacgatgaga gttgcacctg caccaattcc aatcggaaag
     1921 aaggttccca agagatcaaa agttttaaaa ccagtcaaca taggagcata gagtcccaaa
     1981 atcaaaagta aattcgatgg gctgaggcca ggaaccaaga cgccaagggc caatagtgcg
     2041 cctgctagga cgaagttaag aaagctggcg cttaaggttc caacgacaaa atttaaggca
     2101 tagagtccta atccagaaat gataaaggtt gtccataacc aagctaaatc aatcttgtct
     2161 cggtcagatt ctcgagttga ttctttgagg aggctaggaa ctgtaccgat aatagctccc
     2221 gcaaagctcc ataatacaaa gacctgataa ttttcaagca ggtattcaat cgggtaggaa
     2281 aataagccga ttcccagaag cataccgatg gcaactggaa taaagtacaa aacattttct
     2341 ttaaggtctt taaagggatg ggccagaaag ccaatcattc gttcatagat tcctaagatt
     2401 gctgctagaa cccctccgga aattcctggt aggataaatc caagagcaat tacaatccct
     2461 ttaataacgc gtgctaacca tgagagcata tatttcctcc aactatttct atttcaaaaa
     2521 atccttacta tattgtatca caatcagaca caaaaagaaa aagcaaatga taaacaaatg
     2581 cttttaaggt tttaaaaaaa gttttcgaaa ggtttcttct ttatttttta agggagagat
     2641 aacgttgata tctaaatcgt ggtcaaagcc ggcaattttt cctttagatg tgtattggtg
     2701 aatatcataa tctaaatcag ttttaggact gctctccaaa aatcctgagt ctgagccgta
     2761 ggacggaatc caaacagagg taaacttgcc tgtatcaata ctgtgttctt ccatgaagta
     2821 gacaccaacg tagatgccga tgtttttagc acctagtgat gctagttttg ctcgaaagtt
     2881 ttcgacacct tcgttcatat tagacatggt tttgtcttcc acgtcaagcc aatagtaact
     2941 agggctgtaa ggagaggcag cattgtagaa aacttcggca gccttttcca tttcttgggc
     3001 actttttcca gctacataag cgtagacagc aactgggaca ttccgctttt gaagttcagt
     3061 gatatgactc ttataggcct tgtctattcc attgataaat gaagcatcat tttcttttgt
     3121 cgtttgagca ccactgtgaa cacgaacaat agcacctgaa atattttgtg agagggcatc
     3181 gtagttgatt tcctcaggac gctgccagcc agagaggtca ataatcggtt tgtctaagtg
     3241 tttcaaagcc tgtgcttcaa tctgtgctat attggatttt gttttaaacg attggctgtc
     3301 attaagtggg cgattgatga ttaaaatgaa catcataatc cccaaaaaac taaataaaat
     3361 aagtggatga atttgttttc tcatatctta taattctacc ctaaaaatca aaaaaaatca
     3421 aaaaaatggg ttaaggaaga gactttagag cattttttca ttcaagagtg cggaatgatt
     3481 tgaaatatgg tataataaaa gggaatttct acagaaaaga gaagattatg tcaaattttg
     3541 ccattatttt agcagcgggt aaagggactc gcatgaaatc tgatttgcca aaagttttgc
     3601 acaaggttgc gggtatttct atgttggaac atgttttccg tagtgtggga gctatccaac
     3661 ctgaaaagac agtaacagtt gtaggacaca aggcagaatt ggttgaggag gtcttggctg
     3721 gacagacaga atttgtgact caatctgaac agttgggaac tggtcatgca gttatgatga
     3781 cagagcctat cttagaaggt ttgtcaggac acaccttggt cattgcagga gatactcctt
     3841 taatcactgg tgaaagcttg aaaaacttga ttgatttcca tatcaatcat aaaaatgtgg
     3901 ccactatctt gactgctgaa acggataatc cttttggcta tggacgaatt gttcgtaatg
     3961 acaatgctga ggttcttcgt attgttgagc agaaggatgc tacagatttt gaaaagcaaa
     4021 tcaaggaaat caacactgga acatacgtct ttgacaacga gcgtttgttt gaggctttga
     4081 aaaatatcaa taccaataac gctcaaggcg aatactatat tacagacgtc attggtattt
     4141 tccgtgaaac tggtgaaaaa gttggcgctt atactttgaa agattttgat gaaagtcttg
     4201 gggtaaatga ccgtgtggcg cttgcgacag ctgagtcagt tatgcgtcgt cgcatcaatc
     4261 ataaacacat ggtcaacggt gttagctttg tcaatccaga agcaacttat atcgatattg
     4321 atgttgagat tgctccggaa gttcaaatcg aagccaatgt taccttgaaa gggcaaacga
     4381 aaattggtgc tgagactgtt ttgacaaacg gtacttatgt agtggacagc actatcggag
     4441 caggagcggt cattaccaat tctatgattg aggaaagtag tgttgcagac ggtgtgacag
     4501 tcggtcctta tgctcacatt cgtccaaatt caagtctggg tgcccaagtt catattggta
     4561 actttgttga ggtgaaagga tcttcaatcg gtgagaatac caaggctggt catttgactt
     4621 atatcggaaa ctgtgaagtg ggaagcaacg ttaatttcgg tgctggaact attacagtca
     4681 attatgacgg caaaaacaaa tacaagacag tcattggaga caatgtcttt gttggttcaa
     4741 attcaaccat tattgcacca gtagaacttg gtgacaattc cctcgttggt gctggttcaa
     4801 ctattactaa agacgtgcca gcagatgcta ttgctattgg tcgcggtcgt cagatcaata
     4861 aagacgaata tgcaacacgt cttcctcatc atcctaagaa ccagtaggag cctatcatgg
     4921 agtttgaaga aaaaacgctt agccgaaaag aaatctatca aggaccaata tttaaactgg
     4981 tccaagatca ggttgaatta ccagaaggca agggaactgc ccaacgggat ttgattttcc
     5041 acaatggggc tgtctgtgtt ttagcagtaa cggatgaaca aaaacttatc ttggtcaagc
     5101 agtaccgcaa agctatcgag gctgtctctt acgaaattcc agccggaaaa ttggaagtag
     5161 gagaaaacac agcccctgtg gcagctgccc ttcgtgaatt agaggaagaa acagcctata
     5221 cagggaaatt agaactcttg tacgattttt attcagctat tggcttttgt aatgagaagt
     5281 taaaactata tttagcaagc gatttgacaa aagtggaaaa tccgcgtccg caggatgagg
     5341 atgaaacctt ggaagtcctt gaagtgagct tagaagaagc gaaagaatta atccaatcag
     5401 gtcatatttg tgatgccaag acaattatgg ctgttcagta ttgggagttg aagaaaaaat
     5461 agaggaggtc agtatgggta aatctttatt aacggatgaa atgattgaaa gagctaatag
     5521 aggcgaaaaa atttcaggtc ctcctttgct agatgataat gaggagacta agattttacc
     5581 aacctcttct tcccgttttg gttatgccaa tcctaagaat catggtttta gccaggaaac
     5641 cttgaagatt caggtcgaac catctattca taaaagccgt cgcattgaaa ataccaagag
     5701 aaatgtcttc aattctaagt tgaataaaat cttattcgcg gtcatctttc tcttgatttt
     5761 gcttgtttta gcaatgaaac ttttgtaata gaaaaggaat tgaaatgaaa ataggaatta
     5821 ttgctgctat gccagaagaa ctggcttatc tggtccagca tttagataat gcccaggagc
     5881 aagttgtttg tgggaatacc tatcatacag gaaccattgc ttctcatgaa gtcgttcttg
     5941 tagaaagtgg aattggtaag gtcatgtctg ctatgagtgt ggcgattttg gctgatcatt
     6001 tccaggtgga tgcccttatt aatacgggtt cagctggggc agtagcagaa ggtatcgctg
     6061 ttggggatgt cgtgattgct gacaaattag cctatcatga cgtggatgtc acagcttttg
     6121 gctatgctta tggacaaatg gcgcaacaac cgctttattt cgaatcagac aaaacctttg
     6181 ttgctcaaat ccaagagagt ttatctcaat tggaccaaaa ctggcatctt ggtttgattg
     6241 ctacaggaga tagttttgtt gcaggaaatg acaagataga agcgattaag tcccatttcc
     6301 cagaagtttt agccgtggag atggaggggg cagctattgc tcaagcagcg catgccctca
     6361 atctcccagt cttagtcatc agagctatga gtgacaatgc caaccatgaa gcaaacatct
     6421 tttttgatga gtttattatc gaagctggac gtcgctctgc ccaagtcttg ttgacctttt
     6481 tgaaggcttt agattaagcg gaaatttgac agtttttcta gcttatgata agatttaagt
     6541 aaagaaaagc tagaaaacgt ttcagaggat attatgagta ttgaaatgac cgtcagtgag
     6601 attgcagagg tcttaggatt atctcgccaa gcaatcaata accgtgtcaa agaattacca
     6661 gaagaagaca cagataaaaa tgacaaaggg gtaacagttg ttaccagaag tggcttgatt
     6721 aagctagaag aaatctataa aaaaacgatt tttgaagatg agcctgtcag tgaagatgtc
     6781 aaacaacgtg aactgatgga gattctagtg gatgagaaga atgcagaaat tcttcgtctt
     6841 tatgaacaat taaaagccaa ggatcgtcag ttatcagaaa aagacgagca gatgcgtatc
     6901 aaagaccgtc agattgctga gaaagacaaa caattagatc agcaacaaca attgaccctt
     6961 caagccatga aggatcaaga aaatcttaag ctagagctgg accaagcaaa agaagaagtc
     7021 caatccacta agaaaggctt ttttgctcgt ttatttggag gataatcaag gagctgttta
     7081 ggttaaatgc taacctgatg gcttcttttg tttgtgaata gtatagttga ttagaacaga
     7141 gacagtagag gagaggaaca gaatggaacg attagaagat tacattgctt ttgacttaga
     7201 atttaatcag cacgaaggac aaacacactt gattcaagta tcggcagtgc gttttagaga
     7261 tggtcgggaa atcgatgcct atgattccta tgttcatacc agcgtccctc taaaaagctt
     7321 tatcaatggt ttgaccggga ttacagctga gaccttaaaa gatgctcctc cagttgagaa
     7381 agtcttagaa gaattccaag agtttgtggg ttctttgctg atgatagact acaatgctgc
     7441 taaaagtgat ttacctattt tagcagagca tggtttagac tatagccaac agtacaaggt
     7501 ggatttgtat gatgaagctt ttgaacgtcg gagttcagat ttacatggta ttgccaatct
     7561 caaattgcaa actgttgcct catttcttgg atttcaaggt cagtctcata atagtttaga
     7621 ggatgctcgg atgacggcgc gtgtttacga atccttctta gagtcggatc aagctaggga
     7681 attgttagag acagaaagta gcttatcaaa caatcctttt ggtgtcttgg acttgtctca
     7741 attatttgac taggagtgcc tatgaaacct gaaaaaccta aaaaattggg tcttaaacag
     7801 atttacctca atcttgataa aatcctcttt ctatttttct tgatttttat gatagtggag
     7861 tatttgtggg taccattcaa ttcatggttg gctagcttct tattagatca gacaggttat
     7921 ctttttattt cctataacaa tgtcttagcc atccttactc attctccatt gattagtcta
     7981 gcttttttag ccttgattgt aattaacctt ctggttgctt attttcaaat aggactcctc
     8041 tttattggtg ctcgtcatct cctctataat gaaaagcgaa ggctaattga gtatatccgc
     8101 aaggttttcc atgaaagttt tggatttatg aaaaagctaa ctggcgctaa agccttgttt
     8161 atctttttct atatagctat gctttttcct tttatacgga aaatgctgaa gatttattat
     8221 cttaataaaa tcgtcattcc agagtttatc caagcttatt tagaagataa atattggatg
     8281 tggtggctga gcatcctact tctatctctt atctttctct atgtctctgt cagattgatg
     8341 tttgcccttc cgaagattgt atatgatcag ctgactgttc gagaagcagt gatgtttagc
     8401 ttggagaaaa ccaagaagag agttactttt tatgcttgga atttatttta catcttgctc
     8461 aaagcacatt tattatttta tcttcctttg attcctttat tattggctca aactttggta
     8521 gatgatatca ctcagagaga gtctctgatt cttggtattt tgaattttgt cgtgattaaa
     8581 aatctctatt atatggctct gacttatttt ttggttaaat ttgtttcatt tttgacagga
     8641 aaggagctgg atatgcttcc taggagagaa aaagatcaca tcgtgcgatg gggtgtcata
     8701 acttgtgcca gtcttttctt tgccttagaa ggttatattt atctggaggc tcccatggtt
     8761 catctacctc aacttatttc tcaccgaggg gtttccaatg caaatgggat tcaaaataca
     8821 gtagagtcct tggaaactac agcacaactc aaaccagact tggtggagac ggacgtgcag
     8881 gaaacaaaag atgggcagtt tgtcatgatg catgatgcta acttgaaaaa tctagcaggt
     8941 atcaataaaa gtcctcaaga cttaaacttg gaggagctta aagggattga tatttttgaa
     9001 aatggctacc agactaaaat ttcaagcttt gaagattatc tcagtcgagc caacgaactt
     9061 ggtcaaaaat tactaattga aattaaaacc agtaaaaaag atagtccaga catgatgaac
     9121 cgctttttag cccgttatgc tgcaaagctc aagatttatg gacatcaaat ccagtcttta
     9181 gactaccatg ttgtcgaaaa agtaagacag tatgatgccg aactgccagt ttatttcatc
     9241 atgccctaca attctgtctt tcctaaaaca agagcgacag gatatactat ggagtactca
     9301 accttggatg aatattttgt aagcaaacta tggacaacgg atcagaaact ttatgtctgg
     9361 actgtcaatg attcagaagc tatcagcaaa tctcttcact taggagtaga tggagtgatt
     9421 acagatgatt tggaaaaagt tcagcgggaa atagaagtag cccaagaaaa tccagaatat
     9481 acggatttgc tcttgaaaaa agcattggaa ttctttgaat tttagtaata aaaaagagga
     9541 acggttgttc ctcccatgat aggtaagtat tcttgtgaat gcttgctttt ttgtggttgc
     9601 aatccgttta cgagaattgt ttgtattgtt cttgtttcaa tttactttat agtgctttga
     9661 agttggaatg ctacactata acttctaaaa tatagtaaaa tgaaccaaaa atagtacaca
     9721 atgtggtata atctttttat ggcatattca atagattttc gtaaaaaagt tctctcttat
     9781 tgtgaacgaa caggtagtat aacagaagca tcacacgttt tccaaatctc acgtaatacc
     9841 atttatagct ggttaaagct aaaagagaaa acaggagagc taaaccacca agtaaaagga
     9901 acaaaaccaa gaaaagttga tagagataga cttaaaaact atcttactga taatccagac
     9961 gcttatttga ctgaaatagc ttctgaattt ggctgtcatc caactaccat ccactatgca
    10021 ctcaaagcta tgggctacac tcgaaaaaaa gaaccacacc tactatgaac aagacccaga
    10081 aaaagtagcc ttatttctta agaattttaa tagtttaaag cacctagcac aggtctaaca
    10141 aatggtgaat taatcgctcc aatgacttac gaagagatga tgacgagcga cttttttgaa
    10201 gtatggtttc agaagtttct cttaccaaca ttaaccacac catcggttat tatagcgaaa
    10261 tgaaataaga acaggacaaa tcgatcagga cagtaaaatc gaattctaac aatgttttag
    10321 aagtccatat gtactattct agtttcaata taccataact gttcctagtc aacctgcaag
    10381 tcctgtccca gctccaagct cagctccgac tcaagatcct agagtggtag caagcgcttc
    10441 ggctagctca acgagcacac aagctcaaga gcaagttgac aagtctgaac ttcgtgcctt
    10501 gagtcaagag ttagaccaac gcttgaaagc tttggcaaca gtatctgatc cgaaaatcga
    10561 tgcaaccaag gctgtcctcc tagatgctca aaaagttccg gaagatagtg ccttgacaga
    10621 gtaaggtctg catactgcag tagagtctgt gaaggctgcc ttggactctc tcaaagatgt
    10681 gaaagcaaat gctagcgaca gcaagcctgc acaggacaag aaggatgcaa aacaaggaac
    10741 ggaagatagt aaggattcag ataagatgac tgaaacaaac tcagttccgg caggagtgat
    10801 tgtggtcagt ctacttgccc tcctaggcgt gattgccttc tggctgattc gccgtaagaa
    10861 agagtcagaa atccagcaat taagcacgga attgatcaag gttctaggac agctagatgc
    10921 agaaaaagcg gataaaaaag tccttgccaa agcccaaaac cttctccaag aaacccttga
    10981 tttcgtgaaa gaagaaaatg gcttagcaga gacagaaact aaactagtag aggagcttaa
    11041 agcaatcctt gacaaactca agtaaaacat gatttatgaa atgtcagacc taaaagacat
    11101 tttcgttcac aaaagcagcg atgagtaatc cttgtcgttg ctttttggct attttggggg
    11161 ataagatccg ccttgactag caaaagaaaa gattggtcca atagtgcccg atacgatttt
    11221 gcgtagcaga aagcttacaa ataaaattga atatagtaaa ataggattag aattattaag
    11281 aaagttggtt ctttattgga aacgatagta tttttaatct ctgtttttct agcaggtgtt
    11341 ttatcctttt tttctccttg tatttttcct cttctgccag tctatgctgg gattttattg
    11401 gatgatcaag aaagtgcaaa aagcttttct ttgtttggga gaaaggttct ctggtcaggc
    11461 ttgattcgaa cactttgctt tatcgctggt atctctctca ttttctttat tctaggcttt
    11521 ggtgctggtt actttggtca tattctctat gcaaattggt ttcgatatgg catgggagct
    11581 attattatca ttttgggtct tcaccagatg gaaatttttc atttgaagaa attagaagtt
    11641 caaaaaagtt ttacctttaa aaaatcagat tctaatcgtt attggtcagc ttttttactt
    11701 ggtattacct ttagctttgg ttggacacct tgtattggtc cagttttaag ttctgtttta
    11761 gcacttgcgg cttctggagg caatggcgct tggcaaggag cgatttatac tctcatttac
    11821 actctgggca tggcccttcc tttcttggta ttggcactag cttcaggtct agtcatgcca
    11881 tattttagta aaatcaagcg tcatatgatg ctactaaaga aaattggtgg tttcctcatt
    11941 gttttaatgg gaattttgtt actattagga caagtaaatg ttctagctgg aatttttgaa
    12001 taaaggagga caaatgaaaa aagtaatgtt tgctggctta agtctcttgt cattagttgt
    12061 attgatggcc tgtggtgagg aagaaactaa aaagactcaa gcagcacaac agccaaaaca
    12121 acaaacgact gtacaacaaa ttgctgttgg aaaagatgct ccagacttca cattgcaatc
    12181 catggatggc aaagaagtta agttatctga ttttaagggt aaaaaggttt acttgaagtt
    12241 ttgggcttca tggtgtggtc catgcaagaa aagtatgcca gagttgatgg aactagcggc
    12301 gaaaccagat cgtgatttcg aaattcttac tgtcattgca ccaggaattc aaggtgaaaa
    12361 aactgttgag caattcccac aatggttcca ggaacaagga tataaggata tcccagttct
    12421 ttatgatacc aaagcaacca ccttccaagc ttatcaaatt cgaagcattc ctacagaata
    12481 tttaattgat agccaaggaa agattggaaa gattcaattt ggtgctatca gtaatgcgga
    12541 tgcagaagca gcatttaaag aaatgaacta gaatcgataa aatctgatta caagatgtag
    12601 tcagattttg gtaacttcta aaactaactt ccagtttccc acaacctagc ttttagtatg
    12661 agaaaaacgc gtgacatcag tggaaatccg tcttagacta acttccactg gttttctttt
    12721 tcttgatata taagggttca aaagcgaaaa gactcagaaa aagtgcacga caaatagccc
    12781 taaaacagag tcgtcttaga gtaacttcca gttttgggag agagatggaa gttactttga
    12841 gaagttacgg tagtcagatt tttttagaaa aacattttat aaatattcac atatctccta
    12901 tatttatggt aaaatagaat tatcagttta ttttggagtc aaagatgaat atatttagaa
    12961 caaagaatgt tagtttagat aaaacagaga tgcataggca tttgaagtta tgggatttga
    13021 ttttgctggg tatcggagcc atggtaggga caggcgtctt tacaatcaca ggtactgcag
    13081 ctgcaacact tgctggccca gccctagtga tttcaatcgt tatttctgcc ttgtgtgtgg
    13141 gattatcagc cctctttttt gcagaatttg cctcgcgagt acccgctaca ggaggtgcct
    13201 atagttacct ctatgctatc ttaggagaat tccctgcctg gttggctggt tggttaacca
    13261 tgatggagtt catgacagcc atatcaggcg tagcttcggg ttgggcagct tattttaaag
    13321 gcttgctctc tcaatacggg atagcctttc ctcaggcttt aaatggtacc tttaatcctc
    13381 aagcagggac atttgttgat ttattgccta ttcttgtctt ggtcttggtg acttcgcttg
    13441 ttttactaaa tgccaaggca gccttacgct ttaattcgat tctagttatt ttgaaatttt
    13501 ccgctttagc tctctttgtt ttagtaggaa tttggaatat taagtttgat aattggagca
    13561 attttgctcc ttacggtttt ggacaaatct atggagctag cactggtatt atggctggtg
    13621 cgtccttgat gttcttcggt tttttgggat ttgaatccat ctctatggct gtagatgaag
    13681 tcaagactcc tcaaaaaaat attcctagag ggattgtctt atcgctttct atcgtaacca
    13741 ttctctatgc cttggtgacc cttgttttga ctggtgtggt tcactatagt catttaaatg
    13801 tcgatgatgc cgttgccttt gcccttcgta gtgttgggat tagttgggca gccaactatg
    13861 tgtcattagt ggctatcttg accttgatta cagtttgtat ttcgatgacc tatgccctat
    13921 cgcgtatgat ttacagttta gcacgtgacg gcttagtgcc tgctgccttt aaggaactga
    13981 cgaagactag caagatacca aagaatgcta ctatcttgac aggtctagct tcagcagtag
    14041 cagcaggaat gttcccacta gccagtattg cagccttttt aaatatttgt accttagcct
    14101 acttgatcat gttggcttat ggtctgattc gcttacggaa agaaaaagga atgcccaaag
    14161 ctggggaatt taaaacacca ttggtacctc tgttaccaat tttatcgatc atcatttgtt
    14221 tatccttcat gttacagtat aatatgaata cctggattgc tttcctagtt gcgttgttag
    14281 taggaagtat tatttacttc acttatggct ataagcattc taccatagaa gaataaagtg
    14341 aaagtctatt gagttgttga cactcagcag atttttatat gtgaaagaaa tttcaaattt
    14401 tttctaaaaa tatcttgaca gattaaattt tcaggagtag aatatttact agttaattaa
    14461 atggttaagg agttgttcat gaagaaacaa aatttatttt tagtcctgtt aagtgtcttt
    14521 cttttgtgct tgggggcttg tggtcaaaag gaaagtcaga caggaaaggg gatgaaaatt
    14581 gtgaccagtt tttatcctat ctacgctatg gttaaggaag tatctggtga cttgaatgat
    14641 gttcggatga ttcagtcaag tagtggtatt cactcctttg aaccttcggc aaatgatatc
    14701 gcagccatct atgatgcaga tgtctttgtt taccattctc atacactcga atcttgggca
    14761 ggaagtctgg atccaaatct aaaaaaatcc aaagtgaagg tcttagaggc ttctgaggga
    14821 atgaccttgg aacgtgtccc tggactagag gatgtggaag caggggatgg agttgatgaa
    14881 aaaacgctct atgaccctca cacatggcta gatcctgaaa aagctggaga agaagcccaa
    14941 attatcgctg ataaactttc agaggtggat agtgagcata aagagactta tcaaaaaaat
    15001 gcgcaagcct ttatcaaaaa agctcaggaa ttgactaaga aattccaacc aaaatttgaa
    15061 aaagcgactc agaaaacatt tgtaacacaa catacagcct tttcttatct agcgaagaga
    15121 tttgggctta atcaacttgg tattgcaggc atctctcctg aacaagaacc aagtccacga
    15181 caattaacag aaattcagga atttgttaaa acctataagg ttaaaacgat ttttacagaa
    15241 agtaatgctt cttcaaaagt agctgaaact cttgtcaaat caacaggtgt gggtcttaaa
    15301 actctgaatc ctttagaggc agacccacaa aatgacaaga cctatttaga aaatctggaa
    15361 gaaaatatga gtattctagc agaagaatta aagtgaggaa agaatgaaaa tcaataaaaa
    15421 atatctagca ggttcagtgg cagtccttgc cctaagtgtt tgttcctatg aacttggtcg
    15481 tcaccaagct ggtcaggtta agaaagagtc taatcgagtt tcttatatag atggtgatca
    15541 ggctggtcaa aaggcagaaa atttgacacc agatgaagtc agtaagagag aggggatcaa
    15601 cgccgaacaa atcgt
//
LOCUS       DAVLMQ010000039        15232 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000039 DAVLMQ010000000
VERSION     DAVLMQ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15232
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.039"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            153..452
                     /locus_tag="VXF95_001563"
     CDS             153..452
                     /locus_tag="VXF95_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HEV1082089.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSIVSRWNGHSDKGEAPAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            523..2544
                     /locus_tag="VXF95_001564"
     CDS             523..2544
                     /locus_tag="VXF95_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HEV1082090.1"
                     /translation="MKKLFILLSTFFLSFFLAWIIVLRAPQYLYASYDSVSLLRVKKD
                     TQEPTREVFEQELENFANSEQSLIARRIVEPSKDGTTHFIYATYGQGTLPKEFQEASQ
                     ESRERSDPLNSYLLLSGSLTKEKLADKLGDLGYKASADRKIPPYFLAFRILLNPLILI
                     SLAIFGLSFFALVIITRIKEMRAAGIKLFSGQTLLSIMGHSLSTDIKWLLLSALLSFL
                     GGGVVLFSQGLFYPILLATYGFGISFYLLFLLAISILLMLLYLMSLNYKALVPVIKGR
                     LPLKRLMILTLLCQLVAVFTVGYAVKTGLTSYQRLKELEISKQAWQDRADYYQISFGL
                     GDRGKDIENQSKWYAFAKEAIEEEQALYVKDNLLHFANPQGKNEQGETLDTYSPDANT
                     LYVSPSYLDKEKVVVDAETKQKLAHLQKGEFILLLPEHLRSREAELKKVFEERLSYYG
                     KSGEEASAPLDYEMKAHVSYLSMGEKRFVYNNGENPVSTQYLTDPILVVFTPTSTGDS
                     FISLSSWSINAGKQLFIKGYESGLELLKKAGIYEQVSYLKEGRSVYLTRYNEVQTETA
                     TLILGAIVGIASSLLLFYSVNILYFEQFRRDILIKRISGLRFFETHAQYMVSQFASFV
                     FGASLFILSSRDLVIGLLTLLVFLASAVLTLYRQAQKESRVSMTIMKGK"
     gene            2546..3187
                     /locus_tag="VXF95_001565"
     CDS             2546..3187
                     /locus_tag="VXF95_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082091.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTLL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNRVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTASLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            3291..4643
                     /locus_tag="VXF95_001566"
     CDS             3291..4643
                     /locus_tag="VXF95_001566"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HEV1082092.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQCLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYSNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVIPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRDVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELAIQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            4645..5703
                     /locus_tag="VXF95_001567"
     CDS             4645..5703
                     /locus_tag="VXF95_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HEV1082093.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVGWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLAKVEHVGA
                     VTKVSDKNTPEPDELVDIQTHFNPKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELRQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQIENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            5713..6879
                     /gene="divIB"
                     /locus_tag="VXF95_001568"
     CDS             5713..6879
                     /gene="divIB"
                     /locus_tag="VXF95_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HEV1082094.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEESES
                     KEKEEQDKKLAKKATKEKPAKAKIPGIHILRAFTILFLSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKATIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESN"
     gene            7145..7846
                     /gene="pyrF"
                     /locus_tag="VXF95_001569"
     CDS             7145..7846
                     /gene="pyrF"
                     /locus_tag="VXF95_001569"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HEV1082095.1"
                     /translation="MREHRPIIALDFPSFEVVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKILSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            7880..8512
                     /locus_tag="VXF95_001570"
     CDS             7880..8512
                     /locus_tag="VXF95_001570"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HEV1082096.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVDAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQKNWQEG"
     gene            8692..9095
                     /locus_tag="VXF95_001571"
                     /pseudo
     CDS             8692..9095
                     /locus_tag="VXF95_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            9191..9955
                     /locus_tag="VXF95_001572"
     CDS             9191..9955
                     /locus_tag="VXF95_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082097.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKKYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQLLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKIGAIFIPVAYMMVGGIFWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            9955..10707
                     /locus_tag="VXF95_001573"
     CDS             9955..10707
                     /locus_tag="VXF95_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082098.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            10717..11415
                     /locus_tag="VXF95_001574"
     CDS             10717..11415
                     /locus_tag="VXF95_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082099.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDFLNACVLVLFCFMLYALG
                     ANVQMNFACVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            11412..12059
                     /locus_tag="VXF95_001575"
     CDS             11412..12059
                     /locus_tag="VXF95_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082100.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(12146..13012)
                     /locus_tag="VXF95_001576"
     CDS             complement(12146..13012)
                     /locus_tag="VXF95_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1082101.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(13024..13787)
                     /locus_tag="VXF95_001577"
                     /pseudo
     CDS             complement(13024..13787)
                     /locus_tag="VXF95_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            complement(13788..13989)
                     /locus_tag="VXF95_001578"
                     /pseudo
     CDS             complement(13788..13989)
                     /locus_tag="VXF95_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598330.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease"
     gene            complement(14086..14466)
                     /locus_tag="VXF95_001579"
     CDS             complement(14086..14466)
                     /locus_tag="VXF95_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HEV1082102.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            complement(14426..15094)
                     /locus_tag="VXF95_001580"
     CDS             complement(14426..15094)
                     /locus_tag="VXF95_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1082103.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPRIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTRHAGFGNPST
                     LSRK"
BASE COUNT         4574 a         2641 c         3293 g         4724 t
ORIGIN      
        1 aaaatatcta aaaaattcga ttttttcctt gacaacaaat aataaaaatg ttattcttat
       61 cacataagaa agcggtttca acaaaagaga gaggaggatt tattttgttg cattgttgct
      121 cagggtgtgc tttttttgaa agaaaaaata aaatgaaaac gaaaaaacat agattacttg
      181 ctctagctct tatttcaagt tttacattat tgggagctgc atcagctgct gtacaatatc
      241 cagatggagg agtatggaca tatggagaag gttcaggagg tggttgggct ttttcaaatt
      301 actatcatgg taaaaaatat cattattcat ccatcgtgag cagatggaat ggtcattctg
      361 ataaaggaga agctcctgct ggaaaaacct cctatgcatg gatttggact aaatggggag
      421 aacaagtagc attttactgt gattatgact aatcgttcat tgatttaaat cgttcccctt
      481 gtaagaaatt acagggggaa ttttgtttac aaggagtcta ctatgaagaa actattcata
      541 ttattatcaa ctttttttct cagcttcttc cttgcttgga ttattgtctt acgtgcgcca
      601 caatatttat atgcaagcta tgattccgtt tctttacttc gtgtcaaaaa agatactcag
      661 gaaccgacgc gtgaggtatt tgaacaggaa ttggagaatt ttgcaaattc agaacagagt
      721 ttaatagcta gaagaattgt agagccgagt aaggatggga cgactcactt tatttatgca
      781 acttatggtc agggaacttt accaaaagaa ttccaagaag ctagccaaga aagtcgtgaa
      841 cgtagtgatc cgctaaatag ttatctcctt ttgtcaggtt ccttgacgaa agaaaagctt
      901 gccgataaat taggagattt gggttataaa gcaagtgctg accgaaagat accgccctat
      961 tttcttgctt ttcgaatatt actaaatccc cttattttaa ttagtttagc aatatttggc
     1021 ttatctttct ttgctttagt gattatcact cggattaagg aaatgagagc agcaggtata
     1081 aaactctttt ctggtcagac tctcttatcc atcatggggc attctttatc tactgatatc
     1141 aaatggctcc ttctatcagc cctcctttcc ttcctaggtg ggggagtcgt tctttttagt
     1201 caaggtttgt tttatcctat cttgttagcc acctatggtt ttgggattag tttctatctg
     1261 ttgtttttat tggcgatttc aattttacta atgctccttt atctaatgag tttgaattac
     1321 aaagcattag ttcccgttat taaggggaga ttacccctta aacgcctgat gattttaacc
     1381 ctattgtgtc agttggttgc tgtctttaca gtaggatacg ctgttaagac aggtttgacg
     1441 tcttaccaac gattgaaaga acttgaaatt tcaaaacaag catggcagga tagagcagac
     1501 tattatcaaa tttcttttgg cttaggtgat agaggaaaag atatagaaaa tcagagcaag
     1561 tggtatgcct ttgccaagga agcaatcgaa gaagaacaag ctctttatgt aaaggataat
     1621 ctgctccatt ttgccaatcc acaaggaaaa aatgaacagg gagagacact ggatacctat
     1681 agtccagatg ctaatacgct ctatgttagt cccagttatt tggacaagga aaaggtcgtg
     1741 gtagatgctg agaccaaaca gaagttagcc catctccaaa aaggtgagtt tatcctcttg
     1801 ctcccagaac atttgcgctc tcgagaagca gaacttaaga aagtttttga agaaagattg
     1861 agttattatg gaaaatctgg tgaggaggca agtgctcctt tggattatga gatgaaagcg
     1921 cacgttagtt atctttcaat gggagaaaag cggtttgttt ataataacgg tgagaatccc
     1981 gtatccactc agtatttgac tgatccgatt ttagtggtat tcacgccgac ttctacaggt
     2041 gatagtttta tatccttatc tagttggtct atcaatgctg gaaaacaact ctttatcaaa
     2101 ggatatgaga gtgggctaga actcttgaag aaagctggaa tttatgagca agtatcctat
     2161 cttaaagaag gaagaagtgt ttatctaact cgttataatg aagttcaaac tgaaacagca
     2221 actttaatct taggagctat tgtggggata gctagttcct tgttactatt ttattctgtc
     2281 aatattctat atttcgagca attccgccga gatatcttga ttaaacgaat ttcaggttta
     2341 cgattttttg aaacacatgc tcagtatatg gttagccaat ttgccagttt tgtatttggt
     2401 gctagtctct ttattttaag cagtcgagac ttggtgattg gcttgctcac tttattggtc
     2461 tttctagcta gtgcagtttt gacgctttac cgtcaagcgc agaaagaatc tcgtgtttct
     2521 atgacaatta tgaaaggaaa ataggatgat tgaactaaag aatatatcta aaaaatttgg
     2581 aagccgtcag ctattttcag atacgaatct tcattttgaa ggtgggaaaa tttatgcctt
     2641 aatcggtaca agtggctgtg gtaagacaac actcttgaat atgattggac gattggagcc
     2701 atatgacaaa gggcaaatca tctatgatgg cacttctctt aaggacatca agccttctgt
     2761 tttctttaga gattacttgg gatacttatt tcaagatttt ggcttaattg aaagccaaac
     2821 cgtcaaagag aatctcaatc tgggtttagt tggtaaaaag ttgaaggaaa aagagaaaat
     2881 ctctttgatg aaacaagctc taaaccgtgt aaacctctct tatttggatt tgaagcaacc
     2941 tatatttgag ttatcaggag gagaagcaca acgtgttgca ctagcgaaga taattttaaa
     3001 ggatccgcct ttgattcttg cagatgaacc aaccgcttcc ttagacccca aaaactctga
     3061 ggaattactt tccatcctag aatctttaaa aaatccgaat cggaccatta ttattgcgac
     3121 ccacaatcct ctgatttggg agcaagtgga tcaggtcatt cgagttaccg atttatcaca
     3181 tagatgatat ggtaagattc agttagaaga aagagtcaca aacacacttt gtggcttttt
     3241 tatttccata aaaatggtaa aatagtagga gtagaaatgg agttcgagac atgaaagtaa
     3301 tagatcaatt taaaaataag aaagttcttg ttttaggttt ggccaagtct ggtgaatctg
     3361 cggctcgttt gttggacaag ttaggtgcca ttgtgacagt aaatgatggg aaaccattcg
     3421 aggacaatcc agctgcccaa tgtttgctgg aagaagggat caaggtcatt acaggtggcc
     3481 atcctttgga actcttggat gaagagtttg ccctcatggt aaaaaatcca ggtatcccct
     3541 acagcaatcc catgattgaa aaggctttgg ccaagggaat tccagtcttg actgaggtgg
     3601 aattggctta tttgatttca gaagcaccga ttattggtat cacaggatcg aacggtaaga
     3661 caaccacaac gactatgatt ggggaagttt tgactgctgc tgggcaacat ggtcttttat
     3721 cagggaatat cggctatcct gccagtcagg ttgctcaaat agcatcagat aaggacacgc
     3781 ttgttatgga actttcttct ttccaactca tgggtgttca agaattccat ccagagattg
     3841 cggttattac caacctcatg ccaactcata tcgactacca tgggtcattt tcggaatatg
     3901 tagcagccaa gtggaatatc cagaacaaga tgacagcagc tgatttcctt gtcttgaact
     3961 ttaatcaaga cttggcaaaa gacttgactt ccaagacaga agccactgtt ataccatttt
     4021 caacacttga aaaggttgat ggagcttatc tggaagatgg tcaactctac ttccgtggtg
     4081 aagtagtcat ggcagcgaat gaaatcggtg ttccaggtag ccacaatgtg gaaaatgccc
     4141 ttgcgactat tgctgtagcc aagcttcgtg atgtggacaa tcaaaccatc aaggaaactc
     4201 tttcagcctt cggtggtgtc aaacaccgtc tccagtttgt ggatgacatc aagggtgtta
     4261 aattctataa cgacagtaaa tcaactaata tcttggctac tcaaaaagcc ttgtcaggat
     4321 ttgacaacag caaggtcgtc ttgattgcag gtggtttgga ccgtggcaat gagtttgacg
     4381 aattggtgcc agacattact ggactcaaga agatggtcat cctgggtcaa tctgcagaac
     4441 gtgtcaaacg ggcagcagac aaggctggtg tcgcttatgt ggaggcgaca gatattgcag
     4501 atgcgacccg caaggcctat gagcttgcga ttcaaggaga tgtggttctt cttagtcctg
     4561 ccaatgctag ctgggatatg tatgctaact ttgaagtacg tggcgacctc tttatcgaca
     4621 cagtagcgga gttaaaagaa taatatgaaa aaaattgtct ttacaggtgg ggggacggtt
     4681 ggacacgtta ccctcaatct tttgttaatg cccaagttca tcgaagatgg ttgggaagtc
     4741 cactatatcg gggacaagcg tggtatcgaa caccaagaaa tccttaagtc aggtttggat
     4801 gtcaccttcc attctattgc gactggaaaa ttgcgtcgct atttctcttg gcaaaatatg
     4861 ctggacgtct tcaaagttgg ttggggaatt gtccaatcgc tctttatcat gttgcgactg
     4921 cgtccacaga cccttttttc aaaggggggc tttgtctcag taccgcctgt tatcgctgcg
     4981 cgtgtgtcag gagtgcctgt ctttattcac gaatctgacc tgtctatggg cttggccaat
     5041 aaaatcgcct ataaatttgc gactaagatg tattcaacct ttgaacaagc ttcgagtttg
     5101 gctaaggttg agcatgtggg agcggtgacc aaggtttcgg acaaaaacac tccagaacca
     5161 gatgaattgg tggatattca aacccacttt aatcccaaat tgccaactgt attgtttgtt
     5221 ggcggttctg caggcgctcg tgtctttaac caattggtga cagaccataa gaaagaacta
     5281 acagagcgct acaatattat caatctaact ggagattcta gcctgaatga gttgaggcaa
     5341 aatctttttc gtgttgacta tgtgaccgat ctctatcaac ccttgatgga attggctgat
     5401 attgttgtga cacgaggtgg tgccaatacg atttttgagc tcttggcgat agcaaaattg
     5461 catgtcattg tgccgcttgg tcgtgaagct agtcgtggtg accagattga aaatgcagct
     5521 tactttgtaa aaaaaggcta tgcagaagac cttcaagaaa gcgatttgac cttggatagt
     5581 ttggaagaga agctttctca cttactaagt cacaaggaag attaccaagc taagatgaaa
     5641 gcttctaagg aattgaaatc tctagcagat ttttatcaat tgttgaaaaa agatttatca
     5701 taaggaaagt aaatgtcaaa agataagaaa aatgaggaca aagaaatcct cgaagaattg
     5761 aaagagttat cagaatggca gaaacgaaac caagaatatc taaaaaagaa ggctgaagaa
     5821 gaagcggctc tagctgagga gaaggaaaag gaaagacaag ctcggatggg agaagaatct
     5881 gagaagtcag aggacaaaca ggaccaggag agtgaaacag accaggaaga ttcagaatca
     5941 gctaaggaag agtctgaaga aaaagtagca tcctcagagg ctgacaaaga gaaagaagag
     6001 aaagaagaat cagagtctaa agagaaggag gaacaggata aaaagcttgc taaaaaggct
     6061 acaaaggaaa aaccagccaa agcaaagatt cctggtatcc atatcttgcg agccttcacg
     6121 attttatttc taagtctgct tttattgatt gtctctgcct acttgctcag tccttatgcg
     6181 accatgaaag atattcgtgt tgagggaacg gtgcaaacta cagctgatga tattcgacag
     6241 gcttcaggca ttcaggattc ggattatacg attaaccttc tgctagacaa ggcaaaatat
     6301 gaaaagcaga ttaagtctaa ctattgggtt gaatcagctc aacttgtcta tcaatttcca
     6361 actaagttca ctattaaggt caaggaatat gatattgtgg cctactatat ttctggtgaa
     6421 aatcattatc ctattctttc cagtggtcag cttgagacta gttctgtgag tctgaacagt
     6481 ttaccagaaa cttatttatc agttctcttt aatgatagtg aacaaatcaa ggtttttgtc
     6541 tcagaacttg ctcaaattag cccagaactc aaggcgacta tccaaaaggt ggaattagcc
     6601 ccaagcaagg tgacatccga tttaattcga ttgaccatga atgattcgga cgaagtcttg
     6661 gttcctctat ctgaaatgag taagaaactg ccatattaca gtaagattaa gcctcaattg
     6721 tcagaaccga gtgtggtcga catggaagct ggaatctaca gctacactgt ggcggataaa
     6781 ttaattatgg aagctgagga aaaagccaaa caagaggcca aggaagccga gaaaaaacag
     6841 gaagaagaac agaaaaaaca agaggaagag agcaattgaa atcaaacgac ccagcgctca
     6901 ttgcgtcgct aggtttacct tttctcttat agttctttag tgaccatgtt tttacttgac
     6961 aagtgctagt agaaataata gaataataga aaacctttaa agcagtccag agaggcagct
     7021 aaggttagac ggtgaaaggg tggagactac ccatttttcg tggaaccttg ctgttggcag
     7081 gttccttttt tcgtggcttc tgttggccag actctctcac tagtaaaggt aaaaggagaa
     7141 acctatgcga gaacatcgtc caatcattgc tcttgatttt cctagttttg aggtggtcaa
     7201 ggaattttta gctcttttcc cagcagaaga aagcctttat ctcaaggtag ggatggagct
     7261 ttattacgca gcggggcctg agattgtgtc ctacttaaaa ggtttgggtc atagtgtctt
     7321 tttggatctc aaacttcatg acattcccaa tacagtcaag tcagcaatga agatcctatc
     7381 tcagcttggt gtggatatga ccaatgttca tgcggctggt ggtgtagaga tgatgaaggc
     7441 tgcgcgtgaa ggtcttggaa gtcaagctaa attgatcgct gtaactcagc tcacatcaac
     7501 gtcagaagct cagatgcagg agtttcaaaa tatccaaacc agtctgcaag agtctgtgat
     7561 tcactatgcc aagaagacag ctgaagctgg cttggatggt gttgtttgct cggctcagga
     7621 agtacaagtc atcaagcagg ctaccaatcc agattttatc tgtctgacac cagggattcg
     7681 tccagctggt gttgcagttg gagatcaaaa acgagtcatg acacctgctg atgcctatca
     7741 aatcggcagt gactatatcg tagtgggacg tcccattacc caagctgagg atcctgttgc
     7801 agcttatcat gccatcaagg atgaatggac acaggactgg aattaaagaa ctagattaga
     7861 aaaataaaag gagaatacca tgacacttgc taaagatatc gctagccacc tcttgaaaat
     7921 ccaagccgtt tacctcaaac cagaggaacc cttcacttgg gcatctggta tcaagtcacc
     7981 gatttacact gataatcgtg tgacactagc ctatccagaa actcgtaccc taattgaaaa
     8041 tggttttgtg gatgctatca aagaagcctt tcctgaagta gaagtgattg caggaactgc
     8101 aacagcaggg attccacacg gagccattat tgctgataag atggacttgc cttttgccta
     8161 catccgtagc aaaccaaaag accatggagc tggtaatcaa atcgaaggtc gcgtagctca
     8221 aggtcaaaaa atggtagtgg ttgaagacct tatttcaacg ggtggttcag ttcttgaagc
     8281 tgtagcagca gccaagcgag aaggagcaga tgtgcttgga gttgtagcga ttttcagcta
     8341 ccaattgcca aaagcagata agaactttgc agatgctggt gttaaacttg tgacgctttc
     8401 aaactatagc gagcttatcc atctagccca agaagaaggt tacatcacgc cagagggcct
     8461 tgatcttcta aaacgcttta aagaagacca aaaaaattgg caagaaggtt aggtcagtaa
     8521 gataaagaga gacgaggcta ccgagcctct tttaccattt tatttaaaat atgacaatat
     8581 tttaaataaa atgattgaca acgctttctt ttattgatat aatgaaaatg taatatgtat
     8641 caaattgatc aatcaactat cttgtttacc acttcttagg aggacgatgt catgaaaaga
     8701 agaaaaatat attccttttt tgcgtagtta caattgcatc tagtttgttt ctccctacag
     8761 ttttagctag acagattgga aattatgatt taacgttgcc gcgttggggt tcggatacaa
     8821 ctagtgagct tgagaaagaa aacgcctctg ctggaattaa taataatgac agcactggtg
     8881 gcggtaaaag gttaaatacc tctattcgta gcgcctatag tgggtcagat attaccccgg
     8941 tatattcatt ggggtctggc tctaggattg tcatgtacta taatggaggt ggtgacaatt
     9001 atattggttc tggtactaga ttagctatgg cgccacaatt tagaaatcat gtaagaattc
     9061 atacttcagg ttcttggagt ccagattctt attaacttac ttgtcagagt aagccttaaa
     9121 gatggttgat tgtgggtgta gcatgaaaaa agaatgctac accctatttt tattataagg
     9181 aggagtaagg atggaatttt tcatttgtaa tcttgtacga gtcgttcaat cacctcgatt
     9241 ttatatgtct ttatttttga cccttctttg catgagttta ggaaatttcc ttgctttcaa
     9301 tggtatttat aaaattgaag gtttatcgat tttttttgcc gcttcttcta ttcgaggatt
     9361 ttcaccgatt agcctagtag ctgcacttat ctgtacactg ccctattcta gtcagataat
     9421 agaggatgct gagagtcatt ttctaacagc acaattgtgt cgaatttcta aaaagaagta
     9481 tctggctatt gtgggtagta ctgcaattat ttcttctttt ctagtctttt ttctccccta
     9541 tttattatta ttaggaatta atcttttagt gactccttat caggaaattt atattggaga
     9601 ttatagtggt gccttaaaag aattatttga ttccaatcag ttgctctata gtcttgtgac
     9661 gactctctgg tatggagttt ggggcgctgt gttctctatt tttggactag ctagtgcttt
     9721 gctagtgaag aaaaaaatag gagctatttt catcccagtt gcctatatga tggttggtgg
     9781 tattttttgg gctattttag ggctatctta cttagaacct gtgacaacat tagctttggg
     9841 atatcagaaa gatatcagtc tttccttagt tagtgggcat cttgctttta ttttatttgt
     9901 tagttgtttg gttgtttatg gtacattttt tctacattca gaggactatg tataatgaaa
     9961 caatttgttc aattttataa aaaagatttc ttagcagtat tggtttattt tatattactg
    10021 ctatcctgtg ttttatctag tacagtatat ttattgcgct gtcgccaata ttcaatccat
    10081 ccaaatgtat tagaatggat cttagtctta cttcaagata tgacgactgg agtatactgc
    10141 tttccgttca catatatatt gttctttttt tatttgatga ataactattt taataggttg
    10201 gagtgtcgca ttcgtctgaa atcaattaag cactttacca gttttagttt caaattagca
    10261 gctcttagta cggggatttg gacggcgact ttatttttat tgatttttct gattgcattt
    10321 agtaatggtt ttagcttctc tttggagata aaggaggttg attttttaag agaattttat
    10381 ggtataagta ttgcaaacaa tgctagtttc tttataggat tttttttctc ttatatagca
    10441 tactatttct ttttatcctt acttactatt agcagttttt cttggtttaa aaaatcaaac
    10501 atgagcttag tatttctgtt tactttttta tttgtagaat ccttattctg gatttatcag
    10561 ttggacaatg ggataattgg attattgcca atttttcagt atatggtaaa ttccaatccg
    10621 tatgcattga tttattggct tacattacta tctatcataa ttccattgac tgtattttct
    10681 gttcatagaa actggaggag agtgtaaaag ttggaaatgg gaaagttaag tagtcacatg
    10741 tggaggttga atcagataat ctataccaag tacttttggg gttatgttct tttttggata
    10801 ttgatttgtt taggattatg gtattggtta gaaggaaatg atagacttgt tatagaaatt
    10861 ttaaaagggc ctaatctgag tcaaaactct tttttagtct tatctatatg gttgcttcat
    10921 tggtttatta ttcatacatt ttttctagca gttgtatatc gtagaagagc atccgatttc
    10981 tttatggaag tgattcgatt ttcttctatt aagctctgga ttaggtatca gatttggacc
    11041 tgttttcttt atggactcat tttaatcatg gtaaaagttc tagtgattca atttatgtta
    11101 cagttaccaa actgggatat aggagttttg tttatagttg attttttgaa tgcttgtgtg
    11161 ttagtcttgt tttgctttat gttatacgca ctaggagcga atgtacaaat gaactttgct
    11221 tgcgttagtt tctttttact catgattgtg tttggtggtc tatttgtagg aaatcgaact
    11281 aattatctat tttatatttt aaatcgaggg aatggagata taggacgaga tttatttctt
    11341 cagttgctat ttttagtctt tctttttaaa agcattttct atttcactcg tcaaaagagg
    11401 aggtttatag aatgaatgaa ataattacat taaaaaatat tcagttggaa ttaaaaaaaa
    11461 catgtgtttt tcaaaacctt aattttagtt gtaaacaggg ggaaattata ggaattactg
    11521 gtgcgaatgg ctcagggaaa agtgtattgt ttaaattaat agctggttta tatagtccgt
    11581 cttatggaga agtgttaatc aatggggaaa atattgttcc tgagagaaaa attccagcta
    11641 atttgggagc tttgattgaa gaacctggtt ttataaatta ttatagtggc tttaagaatt
    11701 tacaatattt ggcaagcata cgaggagtag ttggtaatca ggaaatcaat gatacactga
    11761 aaatagttgg tctatatgag caaaaagacc agaaagttaa aacttattcg ctaggtatga
    11821 ggaaaaagct agggattgct caagcaatta tggagaatcc ctctattctt ttactagatg
    11881 aacctatgaa tgccttggat aaatcaagtg tagaaaatat gagaacattg tttagaaagc
    11941 tctctagtga aaaagggaca acaattttga ttgctagtca tagtgaagag gatattcgta
    12001 tcttatgtga taaagtatat gcaatagaag ataaagtatg tacactgtgt tcagattgaa
    12061 catcttagat agactcagga tgttataggt aaaatcttaa aaagggattg gatcttaaaa
    12121 tccagttcct tttaagagtt aatgactaat caacttttcc accttcaaca accaggtcat
    12181 ctgctttagc agcgtcaccg taggttaggt gaagtgtttt ttcataggcc ttgtggaaga
    12241 agttttcctt gcctaatttt tcaatatctt tattgatgaa gtctagcaat tcttggttgc
    12301 ctttttgaac tgctgccgca atggtatcgg gatcaccgag ggaagtaatt cctacttcaa
    12361 atcctttatt ttcaagcgcc caagctagaa cttccgtatt gtcagttgaa aaggcatctc
    12421 cacgtccgtc aagaagagct tggtaagagt cactgtattg gtcgtatttt tggagtttga
    12481 tttctggatg attcttttca aaataagtct cagcagtcgt tccttttgtg acaattaagg
    12541 ttttaccttc aagttgtttg acgtctgtaa tgagaccagt cttaggtgat acgacaccca
    12601 gagaaacttt catatatgga agggcaaaat caacttgttt cttacgttcg tcagttactg
    12661 taaagttagc aagagtaata tctaccttgt ttgaaatcaa gtattccgca cggttggcag
    12721 catcgactga aatgtattta accttgacac caaggtcttg agctagttgg ttccctagtt
    12781 caatatcgta gccttggtaa gaaccatcat tgtcaacgta gccaaacggt tttttatctc
    12841 caaacacggc gattcgcagt tcaccgcttt ttttgatttc atcgatagtg cgagctttgg
    12901 cagttgtttt tccagaggat gaaccagcgt ttccacctga gctacaagca gtgataaaga
    12961 taagggcaaa ggcaagtgct aaaacagtta agagtggttt gaatagtttc ataagaatct
    13021 cctttataga tatgagccga attggctaaa gtcaaagacg tttaaaaatt cctgggctcg
    13081 tttggtttgc ggattggtaa agaaggcttg agctgttcct tcttcagcga ttttcccttg
    13141 gtcgaggaag ataatccggt cagcaatggc ttgggcaaac tgcatttcgt gggttactaa
    13201 aatcatggta cggccttctt gggccaaatc attgataagt tccagcacct cacgcaccat
    13261 ttctggatcc agcgaagcag tcacctcgtc aaaaaggatg atttctggat gcattaggag
    13321 ggcacggaca attgcaacac gttgcttctg tccaccagat aattgacggg caaagcaaag
    13381 ctatgttgtt tatccagtaa accgacacga tctagtaatt gcaaagcttc ttccgttact
    13441 tctttcttgt cccttccttg agctttgata gggcctagga tgaggttttg taagacatcc
    13501 agatggggaa agagttcata actttgaaag accatgccaa tcttttggcg aactaggtga
    13561 aaatcttttt tattttcaac gatagactga ccatccagaa gaatatctcc accttgaata
    13621 ctttctaagc cgttgaggca acgaaggagg gtacttttcc cacaaccaaa tggccctagg
    13681 atgacaacaa cttccccttt tttgatttct agagaaagtc cttggaggat gggattgtct
    13741 ccgaaggatt tttttagttc cttgatttct aagatagttt cagacattta gtttctccaa
    13801 tgtttttcta agtgagtgga tagtttggaa atagggtagc aaactgcgaa atataagact
    13861 agaatggttc cataaatcca aaatgaagca gttggggatg gtcaggcgat tgctatcgat
    13921 gatttgttgt ccaactttgg tcacttccac aaccccaatc aaaacaacta atgaagtggt
    13981 tttaatcatc cgagtgacaa gattgatagc ctgcggtagc agtcttctta agacttgtgg
    14041 gatgatgatg tggtagtaaa gttgaacatt agtcaagccg agtgcctatc cactttcaaa
    14101 ctgatgttta gggagagaag tgatagctcc acgtaccaag tctcccattt cagctgttcc
    14161 ccagagggta aaaatgataa tagctgaagt ctcacctgag atattgatat taaagtttcg
    14221 agccaagcca aagtaaacga tgaagagtag caccagctgg ggcatgatac ggataaattc
    14281 cagatacaat cgtgttaaaa atcgtatgat tctagaatgg gaggtcatga tgattcccat
    14341 gactgttccg aacatcatgg ataagaggac agacaggatg gatatcccaa tcgtaacgcc
    14401 caacccctgt aagattctca ggagattatt tccttgaaag agtacttgga ttcccgaatc
    14461 ctgcatggcg ggtcctcctt tctatccagc taaagaccag tgagatgggt agcagcatga
    14521 tcagataagc aactaccaac atagctagcg caatgtctgt ctcatagtag agaccaatca
    14581 aatccttggc gacgtacatg aggtcggcca aagccactgc tgagaaaaca gaggttttct
    14641 tgataaggaa aatgacattg gcactaaagg aggggagtac caccgctgtt gcttgcggaa
    14701 gaaccacata gcgaaagacc tgtagaggtg tcagaccaat agcgaggcca atctcctgct
    14761 gggtttgact gatggcttcc agcccacttc ggaaagattc tgccatatag gagcctccta
    14821 aaaagacaag tccaagcgtt gcacagactt ctgaagatag gacaatcccg attcggggaa
    14881 gaccgaagta gagaaagaag agttgaatca aaaggggcgt attacgtgac aattcaatgt
    14941 aggctgtcgc tacttgcgct aaaacaggga ttcgataatg tcggatgata ctaacgatta
    15001 aaccgagcag aaaggatccc aaaattcccc aaactgcaat atgcaaggtc agaaagaatg
    15061 ccttttgata tagtggtaga tattgttcaa caatggatca atccaaaaat agaacctccc
    15121 atctagaaat aatacagtta ttgtagcact taaaatcttc tttggataat atctattttt
    15181 tattgccgtt ataaggattt ttatcataga cataaaattt ctgaaatttc ca
//
LOCUS       DAVLMQ010000040        15083 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000040 DAVLMQ010000000
VERSION     DAVLMQ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.040"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..255)
                     /locus_tag="VXF95_001581"
                     /pseudo
     CDS             complement(1..255)
                     /locus_tag="VXF95_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            380..838
                     /locus_tag="VXF95_001582"
     CDS             380..838
                     /locus_tag="VXF95_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HEV1082104.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            851..1459
                     /locus_tag="VXF95_001583"
     CDS             851..1459
                     /locus_tag="VXF95_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082105.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            1530..1862
                     /locus_tag="VXF95_001584"
     CDS             1530..1862
                     /locus_tag="VXF95_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082106.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            1873..3288
                     /gene="ply"
                     /locus_tag="VXF95_001585"
     CDS             1873..3288
                     /gene="ply"
                     /locus_tag="VXF95_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HEV1082107.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            4169..4885
                     /locus_tag="VXF95_001586"
     CDS             4169..4885
                     /locus_tag="VXF95_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1082108.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEALETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            5009..5479
                     /locus_tag="VXF95_001587"
     CDS             5009..5479
                     /locus_tag="VXF95_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HEV1082109.1"
                     /translation="MDKPMLVFKRFGHQIHLMVQKEAKRCGIEFMGGPQGQVVHFLDN
                     REKNQDLVLIKDIEQELNITKSVASNLVKRIVQNGLVELEASPVDKRAKFVRLTDKAR
                     SQIQQVKAFFERIDKQLMEDIDEDELLIFEKVLGQLQANIKGIGGENKEISQKN"
     gene            5496..6317
                     /locus_tag="VXF95_001588"
     CDS             5496..6317
                     /locus_tag="VXF95_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082110.1"
                     /translation="MILLAILFTCFSVYLELEVPTYISKITDLLGSQGTNLDELWQPA
                     SMMMGMPFLAFLSVVAVGFFASRVAASYTSRLRSDIFNRVLDYSQTEIKKFSIPSLLM
                     RTTNDITQVQMLITMGLQVVTCGPIMAIWAIGKILGHSEYWLWAVLVAVIVNVLMTTV
                     LMTLAFPKQSLIQGLTDKLNSITRESLTGIRVVRAYNAEDYQNEKFAAVNDELTRLNL
                     FVNRLMAILNPIMMGISSGLSVAIYWIGAYVINDAAPIARLPLFSDMIVFMSYAM"
     gene            6324..7355
                     /locus_tag="VXF95_001589"
     CDS             6324..7355
                     /locus_tag="VXF95_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1082111.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPVQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSTGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQKVAIVGPTGTGKTTIVNLLMKFYEIDKGSIHI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMAQGGFYADLYNS
                     QFTEDEAEE"
     gene            7421..7783
                     /locus_tag="VXF95_001590"
     CDS             7421..7783
                     /locus_tag="VXF95_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HEV1082112.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLACLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            7780..8283
                     /locus_tag="VXF95_001591"
     CDS             7780..8283
                     /locus_tag="VXF95_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HEV1082113.1"
                     /translation="MKNYQEWYRNISSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSAGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            8397..8843
                     /locus_tag="VXF95_001592"
     CDS             8397..8843
                     /locus_tag="VXF95_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1082114.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKAPRLTF
                     YKGTGEYYLDLSEILFFETEGSKIYAHNQKEAYEVRLKLYELESILPRYFNRVSKSTI
                     ANIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            8849..9523
                     /locus_tag="VXF95_001593"
     CDS             8849..9523
                     /locus_tag="VXF95_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082115.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVSLMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGTAKADAPVAPTSKTLIIRGDVAFGKL
                     ELVYVK"
     gene            9779..9967
                     /locus_tag="VXF95_001594"
                     /pseudo
     CDS             9779..9967
                     /locus_tag="VXF95_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647592.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein A"
     gene            10217..10516
                     /locus_tag="VXF95_001595"
     CDS             10217..10516
                     /locus_tag="VXF95_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HEV1082116.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDHKLMKTQEELTA
                     IVRDHFSDMGEIATLYVQVYESSLESLLGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            10513..10830
                     /locus_tag="VXF95_001596"
     CDS             10513..10830
                     /locus_tag="VXF95_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HEV1082117.1"
                     /translation="MIQPASLEELASLVEKDGKKVFLFVADWCGDCRYIYPALPEIEE
                     SNPEFTFIRVDRDQYIDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKQQINDFLA
                     GLK"
     gene            10846..11472
                     /locus_tag="VXF95_001597"
     CDS             10846..11472
                     /locus_tag="VXF95_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HEV1082118.1"
                     /translation="MIFTYNKEHVGDVLMVIVKNSGDAKLNVERKDKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            11505..12266
                     /locus_tag="VXF95_001598"
     CDS             11505..12266
                     /locus_tag="VXF95_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HEV1082119.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            12344..12739
                     /locus_tag="VXF95_001599"
     CDS             12344..12739
                     /locus_tag="VXF95_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HEV1082120.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            13009..13293
                     /gene="groES"
                     /locus_tag="VXF95_001600"
     CDS             13009..13293
                     /gene="groES"
                     /locus_tag="VXF95_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HEV1082121.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            13309..14931
                     /gene="groL"
                     /locus_tag="VXF95_001601"
     CDS             13309..14931
                     /gene="groL"
                     /locus_tag="VXF95_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HEV1082122.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISNRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEATGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
BASE COUNT         4466 a         2755 c         3486 g         4376 t
ORIGIN      
        1 gatagcgcat ggttacaggc tttatcttca actgttagcg gcttgagttt gctggattta
       61 cgtggagttt gtgcttgagg atatatcttc atgagccctt gataaccact gtcagccaag
      121 attttaccag cttgtccgac ttttttgata agctgttttt aatccagcta acatctcttc
      181 aaaagtggta cgctgaacac taacaagacg cttaaatcgt gcatcagtta gttgtttact
      241 tgcttcatca ttcatagaac tactatacca tattttgttt cgcaggaagt ctaataagtt
      301 atagtccagt ttttactata ctttgatatt caaatatgtt atactatggt tatcaaagta
      361 aatgaaagga gttacgaata tgacgccaga agaaatgtac ctgacagagc gattagacgt
      421 acagatagct cattttttaa agaaaagcgt tcaacatcgt agacgctata aggtattaaa
      481 aataacagaa atcgtggcag gtttcctcat agctgtcttt tgtgctattc ctatgccagg
      541 tgatcgctac cgtttgattt cggttgcctt atccagtctc ggcttgctgt gtgaggggat
      601 tatcaatttg tataatgcaa aggaaaattg gatttcttac caaaaaactg cgcaactcct
      661 ggagaaagaa aaattcctct atcaatgcca aacggagaaa tatgcaggaa agaccaaggc
      721 ttttgcccta tttgtcaaga catgcgaagg tcttatctca gaggagatta accagtggga
      781 aagtatccag tcaaaagaag tggcagctag tgcagatgct ccagttaaaa aagagtagga
      841 ggtagaggaa atgtctcaat ccagctacct gtcgcccttg ctctggttaa aaaaagaagc
      901 cgataaggaa aagatgagcg cgacccagtg ccagatattt ttcttttact atcaaatgtt
      961 tgagctctta tttgctagag aaagcgacat gaaagactta tgtctgggaa cgaaaggttt
     1021 ttatttctcg cagttagaga aaaatttgct ttctggagtt tcccgatttc taaaaaactt
     1081 ggaggggaaa gtaactctca aggctaacca agaagtatca gctcgcaaag ccctttttct
     1141 agccttgaca actagccaat cagattggca ggagttagct cctgtttttg atttttatca
     1201 gactatcggg aggcttgaaa atccttctct cttgagttct caggacagac aacatctgat
     1261 gtggatttac cagtcagctt tggagaagga ttatattgtc aaggttattg gcgacaagca
     1321 ttttgtattg aagagacaag atgctactaa attgacagcg cgccaaactc aaactttgga
     1381 aattctgagt caatcagaag acttggtcaa tcctgtctat gttacattag gagaaaaggg
     1441 ggtgctcttg cttgattaag agaggagatg ttgtagctct ttatttgcct tttccgacta
     1501 ttagtagcga tttggctgtg aagaatcata tgtatatctg tattgacaac agcatgacta
     1561 aaaacaaaga gttggttaaa aatcagacct tcaaaccagc tctcttgacc agacgtttgg
     1621 tcaagaactt tatgatagaa gagccggatc tagctcgtaa tccttttaca agaccaacct
     1681 tgattgactt agataaggta tttatgttgg ataatacggt tattccgact tcttatctag
     1741 ccagacggcg acgcaatgtc tcagaagaat tgtacgagga aattttggat cacttagtcc
     1801 aaccacggct gatttcgctg aacaagtctg agtttatgca actcaatcca ggaacttatt
     1861 aggaggtaga agatggcaaa taaagcagta aatgacttta tactagctat gaattacgat
     1921 aaaaagaaac tcttgaccca tcagggagaa agtattgaaa atcgtttcat caaagagggt
     1981 aatcagctac ccgatgagtt tgttgttatc gaaagaaaga agcggagctt gtcgacaaat
     2041 acaagtgata tttctgtaac agctaccaac gacagtcgcc tctatcctgg agcacttctc
     2101 gtagtggatg agaccttgtt agagaataat cccactcttc ttgcggtcga tcgtgctccg
     2161 atgacttata gtattgattt gcctggtttg gcaagtagcg atagctttct ccaagtggaa
     2221 gaccccagca attcgagtgt tcgcggagcg gtaaacgatt tgttggctaa gtggcatcaa
     2281 gattatggtc aggtcaataa tgtcccagct agaatgcagt atgaaaaaat cacggctcac
     2341 agcatggaac aactcaaggt caagtttggt tctgactttg aaaagacagg gaattctctt
     2401 gatattgatt ttaactctgt ccattcaggc gaaaagcaga ttcagattgt taattttaag
     2461 cagatttatt atacagtcag cgtagatgct gttaaaaatc caggagatgt gtttcaagat
     2521 actgtaacgg tagaggattt aaaacagaga ggaatttctg cagagcgtcc tttggtctat
     2581 atttcgagtg ttgcttatgg gcgccaagtc tatctcaagt tggaaaccac gagtaagagt
     2641 gatgaagtag aggctgcttt tgaagctttg ataaaaggag tcaaggtagc tcctcagaca
     2701 gagtggaagc agattttgga caatacagaa gtgaaggcgg ttattttagg gggcgaccca
     2761 agttcgggtg cccgagttgt aacaggcaag gtggatatgg tagaggactt gattcaagaa
     2821 ggcagtcgct ttacagcaga tcatccaggc ttgccgattt cctatacaac ttctttttta
     2881 cgtgacaatg tagttgcgac ctttcaaaac agtacagact atgttgagac taaggttaca
     2941 gcttacagaa acggagattt actgctggat catagtggtg cctatgttgc ccaatattat
     3001 attacttggg atgaattatc ctatgatcat caaggtaagg aagtcttgac tcctaaggct
     3061 tgggacagaa atgggcagga tttgacggct cactttacca ctagtattcc tttaaaaggg
     3121 aatgttcgta atctctctgt caaaattaga gagtgtaccg ggcttgcctg ggaatggtgg
     3181 cgtacggttt atgaaaaaac cgatttgcca ctagtgcgta agcggacgat ttctatttgg
     3241 ggaacaactc tctatccgca ggtagaagat aaggtagaaa atgactagga gaagagaatg
     3301 cttgcgacaa aaagaggcga tgatctctct gcggatatct gaaagtttat ctcttgccta
     3361 gcgatttcca ttggagtatg ctcgtgatgt taaaatgagt ctatcaaaca ggatgtgtaa
     3421 aaaagtaaaa agggtagcca attccttgat atacagggga ttgattatcc tttacttgtt
     3481 ttagatgatt ggaaattcaa gaatgacacg tatcggaaat attttgctgt ttatatctaa
     3541 tacccattta tggaaaaaat gaaattaaat atgaacaaat caattgctag caatggttta
     3601 gaagtgccag tgtactagtc taacttctcc atcttgggaa cacgtaaatt atactcttcg
     3661 aaaatctctt caaaccaggt cagccctatc cgcaacttca aaacagtgtt ttgagcaccc
     3721 tgcggctagc tttctggttt gttctttgat ttttattgag tattagaggt ttgcttagaa
     3781 actcttctat tgatttctta gaatacaata gcgcctataa gaactgttgg atttcaaagt
     3841 atttacttga actatgatat gtctggagta gactgtcaac aaaaggtgca gtatgattgt
     3901 ttttgtcgct tatatctaca aacttcaaac agtaatttga gctgactttg tcaaacttgg
     3961 ctgaaacttt ctatttgcag ataatggtct agtttgtttt ttgaatgtgg atgagtgtct
     4021 gttgataaag atagaaaggc aagaccgtct tagcaggtaa agtgctatcc tagcttgatt
     4081 tgctaataaa atccatttcc tctagtgaaa atcaaaaaaa cttgtgttat aataagaaag
     4141 attaaaatgt gaaaaaagga gattcctaat gggacgtaaa tgggccaata tcgtagccaa
     4201 gaaaacggct aaagatggag ccaactctaa agtatatgca aaatttggtg tagaaatcta
     4261 tgtagcagct aaaaaaggtg atccagatcc agaatcaaac tcagctttga aattcgttat
     4321 cgaccgtgct aaacaagccc aagtgccaaa acacattatc gataaagcga ttgataaagc
     4381 caaaggaaac acagacgaaa cctttacaga aggacgttac gaaggttttg ggccaaatgg
     4441 ctctatgcta attgtggata ctttgacttc taacgttaac cgtacagcag ccaatgtccg
     4501 tgcagccttt ggtaaaaacg gcggaaacat gggcgcttca ggttctgttt cttacctttt
     4561 tgacaacaaa ggtgttattg tatttggagg tgaagatgcg gacgcagtct ttgagcaatt
     4621 gctcgaagcg gatgtggatg tggatgacgt agaagcacaa gaaggtacaa tcacagttta
     4681 cacagcgcca actgaccttc acaaggctat cgttgccctc cgtgagtctg gtattgaaga
     4741 attccaagtg actgaattgg aaatgattcc tcagtcagaa gtggaattgt caggcgaagc
     4801 ccttgaaacc tttgaaaaac tttacagcgt tcttgaagac gacgaagacg tccaaaagat
     4861 ttatacgaac gtagatgggt tttaatttaa cctatagaac atgatcctaa gtgagaaaat
     4921 cacttgggat ttttttaatc aagaaaatag ttctcataga aatttaatta ttctccagag
     4981 aactattttt atttagaagg gggagattat ggataaaccg atgttagtct ttaagcgttt
     5041 tggtcatcaa attcacctga tggtgcaaaa ggaagccaaa cgttgcggca ttgaatttat
     5101 gggtgggccg caaggtcagg ttgtgcattt tttggataat cgcgagaaaa accaagactt
     5161 ggtcttgatt aaagatatcg agcaggaact caatattacc aagtctgttg ctagtaatct
     5221 ggttaagcgt atagtgcaaa atggtttggt ggaattggag gcgagtcctg ttgataagcg
     5281 ggctaagttt gttcgtctga cggacaaagc acgttctcag atacaacagg ttaaggcttt
     5341 ttttgaacgc atagacaagc agttgatgga agacattgat gaagatgaat tactgatttt
     5401 tgagaaagtt ctcggtcaac tacaggcaaa tatcaaggga ataggaggag agaataaaga
     5461 aattagccaa aagaattagt agaaaagaat gggggatgat tttactagcc attctcttta
     5521 cttgcttttc ggtctatcta gagttggaag tgccgaccta tatctcgaaa attacggatt
     5581 tgctaggtag tcaaggaact aatttagatg agttgtggca gccggcaagc atgatgatgg
     5641 gaatgccctt tcttgccttc ttgtccgtag ttgcagttgg attttttgca tcccgagtgg
     5701 cggcttctta tactagtagg ctgagaagtg atatttttaa ccgagttttg gattactcgc
     5761 agacagagat taagaaattt tcaattccta gcctcttgat gcgtactacc aatgacatta
     5821 ctcaagttca aatgttgatt actatgggct tgcaagtggt aacgtgtggt ccaattatgg
     5881 ctatctgggc tattgggaag attttaggtc attcagaata ctggctctgg gccgtacttg
     5941 tggcagtgat tgtcaacgtc ctgatgacga ccgttttgat gacgctagcc tttccaaaac
     6001 agtccttgat tcaggggctg acagataaac tgaacagtat cactcgtgag agtttaacag
     6061 gtattcgtgt cgttcgtgcc tacaatgcag aggattatca aaatgaaaaa tttgcagcag
     6121 taaatgatga attgacccgt ttaaatttgt ttgtcaaccg tcttatggct attttgaatc
     6181 ctatcatgat ggggatttca agtggtttga gtgtggcgat ttactggatt ggggcctatg
     6241 tgattaacga cgctgctccg atagcgcgtc tgcctctctt tagtgacatg attgttttca
     6301 tgtcttatgc catgtaggtt gtcatggact tccttctcat gggagcactc ttcatcgttc
     6361 ttccccgaac tatggtctct gctaagcgga ttaatcaagt tttagatttg cattcttcta
     6421 tccaaaaccc tgttcaagta cagctgactg atgaaaactt caaaggtcag gtcgagttta
     6481 aggatgtgac cttccgctat gcggcaaatt cggaggcagt tattgaacat gttagcttta
     6541 aagcagaaac tggtcaaaca gtggccttta ttgggtcaac aggttctggt aaatcaactc
     6601 tggtcaatct gattccacgt ttctacgacg tgtcagcagg agaaattctg gtggacggtg
     6661 tcaatgttca agactatgac ttctctgcga cagctcatgc tggtcaaaag gttgccattg
     6721 ttgggccgac tgggactggt aagacaacca ttgtcaatct tttgatgaaa ttctatgaga
     6781 ttgataaggg aagtattcac attgatggtg tggataccaa ggctatgacg cgttcagaag
     6841 tgcatgatgc cttttcaatg gtcttgcagg atacctggct ctttgaagga actattcgag
     6901 acaatctcat ctataatcaa atagggatta gtgatgaacg aatgatggaa gctagtaagg
     6961 ctgtgggaat tcaccacttt attatgacct tgccagatgg ctatgatacc atcttggatg
     7021 acaccgtgac cttgtctgta ggacaaaaac aactattgac tattgctcgt gcccttctta
     7081 aggatgcacc gcttttgatt ttggatgagg cgacttcttc tgttgacaca cggacagagg
     7141 aattgatcca aaaagccatg gaccgtttga tggaaggacg cacatccttt gtcattgccc
     7201 accgcttgtc aaccatccga aatgcagact tgatcttggt catgaaagat ggaaatatca
     7261 tcgagcaagg caactatgag gaactgatgg cgcaaggtgg cttctacgct gacttgtaca
     7321 atagtcaatt tacagaagat gaagcagaag aataaatcaa aagaaggctt gacggccttc
     7381 tttttcttat ttatactagt acacatagaa agagagaagt atgagtcaga aattatacaa
     7441 tatgaaattt gctgctgtct acttagcctt gattgcaaaa gttgagcgaa agggtggaaa
     7501 ggcagagtca gttcaccaag tgaccagttg gttgacaggg tatgaagtga gtgatgttct
     7561 tgcttgtctg gatagggatg ttacttacgg agattttttt agacaagcac catattatgt
     7621 ccctgaacga attgcaatta cagggaagat ttgcggtgtc cgtattgagg aaattgatga
     7681 tcctctgatg caggaaatac gtcgcttgga caagctagtg gattggcttg ccaaggggaa
     7741 aacatctcaa caagttctag aaaagtatga gaagcataaa tgaaaaatta tcaagaatgg
     7801 tatcgaaata tcagctccag actaactagt cgtccaattc ttttattcct attacgcagt
     7861 ttcaatcgtt tgatgacagt cgccatgccc ctggtctatc tgatcttgct agtcaccact
     7921 tacctgcaac taggacttgg tcagcaagtt ggggtttatg tgcttattcc tgcatcaggt
     7981 tttgtggcct tgtccctgtt tcgtaagaaa atcaatcacc cgagacctta tgaaacttgg
     8041 gatatctgtc cccttcttga taaggatagt gcgggacggt cgatgcccag tcgccatgtc
     8101 ttttcggcaa ctatcatctc catggcctgt ctgcatgcta gtctacctat tggcttagta
     8161 tgcttgatct tttcagcttt gctggggttg gtgagggttt tagggggtgt tcattatccc
     8221 aaggatgtct tggttggcta tgcttgtggt ttggtgtggg gattcctttt cttcctattc
     8281 tgacatgtaa gttaagctag tcctacaacc acttactgct tcaaattgac cacttgcttt
     8341 tttgcccttg tattcctaac ttagctttga tatagtagag tcagaaagga gatgtgatga
     8401 agttacgaat tgagattgac ggcaatttag aggagactga aattgtcatc aagaccccca
     8461 ctttgacaga tgaaattgca gacttgcaac ggctcttgca agagtcaaag gctccgaggt
     8521 tgacttttta caaggggaca ggtgaatatt atctagacct gtcagaaatt ctcttctttg
     8581 aaacagaagg gagcaagatc tacgctcata accagaagga agcttatgag gttcgcctca
     8641 agctctatga gttggagtct atcttgcctc gctattttaa tcgagtttcc aagtcaacga
     8701 tcgcaaacat ccgtcagatt tactcagtgg acaagtcctt ttcaggaacg ggcaccattt
     8761 ccttttatca gacgcacaag gaggttcatg tctcacggca ttaccaatcc ctcctaaaag
     8821 aaaatctaag aaacatgagg taaaaaacat gaaaaagaaa gcatttggta ttgtgttact
     8881 tgtactagca gctttaatat tagtacaagg aaattttgga atcccttctc taggagggca
     8941 catttggccc ttgattggta ttgctttttt tgcctaccaa tcagttggag ctttgttgcg
     9001 tcgccactta acttcagcct cttttacagc tctagtatcc ttaatgattg ctaaccactt
     9061 ttatggcatt ttaccgattc caaaccagac actaatctgg gcaggagttc taatcgttct
     9121 cggagtaaat atgttgactc attctaacag aacttggaat gggaaaaaat ggtggtatga
     9181 tggtgaaaaa aacattctta tagataagga agttgctttt gggacaggga ctttctacaa
     9241 gcaagaccaa gaattggtag aagaccaagt agaagttggt tttggcaatg caaaaatcta
     9301 ctatgacaat gcagagatgt taggtgattt tgcaacttta aatattgaag tagcttttgg
     9361 taatgcaact gtctatgttc cgcaacactg gcgtgtcgat ttgaaagtag aaacatcctt
     9421 tggtacagcc aaggcggacg ctcctgtagc gccaacaagc aaaaccttga ttattcgtgg
     9481 agacgtggcc tttgggaagt tggagcttgt ctacgttaaa taaaaaaatc ttcacttaaa
     9541 ccatcaaaat agacgtacta agagtaggaa attgatgcct tgctctgatt tcagttctat
     9601 ggttgttaga ctttaaaaaa tgaaatgttg cctttaaaag ttgtatattt ttcgatattt
     9661 tgactcttac gtttgatgta tctatgtcct acagcgtgga tgatgtagtg taaaatgctt
     9721 taaaaaaaaa atgaatgata ttggacagtt tttttgaact tttaattgct caggagccat
     9781 gaaagcaagc gcttgggttt atgacaaggg agaatggtat tatgtaagtt cttctggttc
     9841 catgattgcg aatgattggg tcaaagacaa tggcaagtag tattatctgg cttcatcagg
     9901 taagatgctt cgcaatacct acacacctga tagttactac gttggcaact taggtgcctg
     9961 gcaataagaa taatactctt cgaaaatctc ttcaaaccac gtcagcttca tccacaacct
    10021 caaaacagtg ttttgagctg acttcgtcag ttctatctac aacctcaaag cagtgctttg
    10081 agcagcctgc ggctagcttc ctagtttggt ctttgatttt cattgagtat aagaagtcct
    10141 tttccttaaa ggaagaggct ttttacttgc ttttttgctg tttcctcatt tgtcctaaag
    10201 ccttttttgt gttaaaatga atggtatgaa agctaaaaaa atgtggatgg caggtctggc
    10261 tctgcttggt attgggagcc ttgcccttgc tacgaaaaaa gttgcagatg accataagct
    10321 catgaagact caggaagagt tgacagcgat tgtacgagac catttttcag acatggggga
    10381 aattgcgacc ctctatgttc aagtctatga aagcagtcta gagagcttgc ttggtggcgt
    10441 tatttttgag gatggccgtc attatacctt tgtctatgaa aatgaagacc tagtctatga
    10501 ggaggaagtc ttatgataca accagcaagt ttagaagaat tggcatcttt agtagaaaaa
    10561 gacggtaaga aggtcttcct ttttgtggcg gactggtgtg gcgattgccg ttatatctat
    10621 cctgccttac cagaaattga ggagagtaat ccagagttta cctttattcg agtggataga
    10681 gaccagtata tagatttggc caaactctgg gatgtatatg gaatccctag ccttgttgtt
    10741 ctagaaaagg acaaggaaat cggtcgtttt gtcaatcgcg accgtaaaag caagcaacaa
    10801 attaacgatt ttttagcagg attgaaatag gagaaaaagg aaacaatgat ttttacatat
    10861 aacaaagaac atgtcggtga tgtccttatg gtcatcgtga aaaatagcgg agatgctaaa
    10921 ctgaatgtgg aacgcaaaga caaggtagcc cgtgttttcc tcaaagaaaa tggggaaaca
    10981 gtagcttgga acatttttga ggtttcgagc ttgtttgaaa ttgcagagcg cggtcaagtc
    11041 tttttatcag atgagcaagt cgctcgtttg aaccaagaat tacaggcgga aggttttaca
    11101 gaagaaattg ttaatgataa ggaacctaag tttgttgttg gtgaaattgt cgagatggta
    11161 gctcatccag acagtgacca cctcaacatc tgccaagttg cagtcgcaag tgacaagata
    11221 gtgcaaatcg ttgcaggagc acctaatgcg cgtgttgggt tgaaaaccat tgtggctctt
    11281 cctggtgcca tgatgccaaa agggaatttc attttcccag gcgaacttcg tggtgaaaag
    11341 agttttggga tgatgtgtag tcctcgtgaa ttgcatttgc caaatgctcc gcaaaaacgt
    11401 ggggtgcttg aattatcaga agaccaagtt gtcggaacac cgttcgaccc agcgaaacac
    11461 tggactgcct aggaacttgt cagcatctga tagaaggaaa taagatggca aaaaatgtag
    11521 tgattacggg agcaacctca ggaatcggtg aagcgattgc gcgtgcttat ctggagcagg
    11581 gtgaggatgt cgttctaaca ggacgacgga tagacagatt agaaatcctc aagtcggagt
    11641 ttgcagtaag ctttccaaat caaaccgtct ggacttttcc actagatgtg acggatatgg
    11701 tcatggtgaa gactgtttgc tctgatattc tagaaacgat agggaggatt gatatcttgg
    11761 tcaacaacgc cggactggct cttgacttgg ctccctatca agactatgag gagttggata
    11821 tgttgaccat gttggatacc aatgttaaag gtctgatggc ggttactcgc tgtttcttgc
    11881 cagcaatgat aaaagtcaat caaggtcata ttatcaatat ggggtcaacc gcaggaatct
    11941 acgcctatgc tggtgccgct gtttactcag ctaccaaggc agcggttaag accttttcgg
    12001 atggactgcg aattgatacc atcgcaacgg atatcaaggt gacaaccatt cagcctggga
    12061 ttgtcgaaac agatttctca actgttcgtt ttcatggtga taaagagcgg gctgcgtccg
    12121 tttaccaagg aatagaagcc ttgcaagctc aggatattgc agacacagta gtctatgtga
    12181 ccagtcagcc tcgccgtgtt cagattacag atatgaccat tatggccaat caacaggcga
    12241 caggtttcat gattcataaa aaataagaaa tttcctcgaa aagttacaaa tttctgtaac
    12301 tttttttgat ttcctacgaa tagataagta ggaggaagaa aatatgtata ataaagttat
    12361 catgattggg cgtttaacgt ctacaccaga attgcacaaa accaacaatg acaagtcggt
    12421 agcgcgagca actatcgctg tgaaccgtcg ttacaaagac caaaacggtg aacgtgaagc
    12481 tgattttgtc aatatggtcc tatggggcag actagcagaa actttggcaa gctacgcaac
    12541 caaaggtagt ctcatttccg ttgatggaga attgcgtacc cgtcgctttg agaaaaatgg
    12601 ccaaatgaac tacgtgaccg aagtacttgt cacaggattc caactcttgg aaagtcgtgc
    12661 tcaacgtgct atgcgtgaaa ataatgcagg ccaagatttg gcagatttgg tcttggaaga
    12721 ggaagaattg ccattttaat actcttcgaa aatctcttca aaccacgtta gctttatcca
    12781 caacctcaaa gcagtgcttt gagcagcctg cggctagctt cctagtttgc tctttgattt
    12841 tcattgagta taaacattaa aaagtctgag ttggtctcag gctttttatc ttgagaaagt
    12901 cagacttttt tcttgactat ttctgaccaa gtgatacaat agaattatga attagcactc
    12961 aagttcaaag agtgctaata atatctatct cattatggag gaaatcagat gttgaaacca
    13021 ttaggggacc gtgtggtctt aaaaatagaa gaaaaagaac aaaccgttgg gggctttgtc
    13081 cttgcaggct cagcccaaga aaaaaccaaa acagctcaag ttgtggctac tggacaaggt
    13141 gttcgtacct tgaacggtga cttggttgct ccaagtgtta aaactggaga tcgtgtctta
    13201 gttgaagccc acgcaggtct tgatgtcaaa gatggcgatg aaaagtacat catcgtaggc
    13261 gaagctaaca ttttggcaat cattgaggaa tagaaggaga aagtaagtat gtcaaaagaa
    13321 attaaatttt catcagatgc ccgttcagcc atggttcgtg gtgtcgatat tcttgcagac
    13381 actgttaaag taaccttggg accaaaaggt cgcaatgtcg ttcttgaaaa gtcattcggt
    13441 tcacccttga ttaccaatga cggtgtgacc attgccaaag aaatcgaatt ggaagaccat
    13501 tttgaaaata tgggtgctaa gttagtatca gaagtagctt ctaaaaccaa tgatatcgca
    13561 ggtgacggga ctacgactgc aacagtcttg acccaagcta tcgtccgtga aggaatcaaa
    13621 aacgtcacag caggtgcaaa tccaatcggt attcgtcgtg ggattgaaac agcagttgcc
    13681 gcagcagttg aagctttgaa aaacaacgcc atccctgttg ccaataaaga agctatcgct
    13741 caagttgcag ccgtatcttc tcgttctgaa aaagttggtg agtacatctc tgaagcaatg
    13801 gaaaaagttg gcaaagacgg tgtcatcacc atcgaagagt cacgtggtat ggaaacagag
    13861 cttgaagtcg tagaaggaat gcagtttgac cgtggttacc tttcacagta catggtgact
    13921 gatagcgaaa aaatggtggc tgaccttgaa aatccgtaca ttttgattac agacaagaaa
    13981 atttccaata tccaagaaat cttgccactt ttggaaagca ttctccaaag caatcgtcca
    14041 ctcttgatta ttgcggatga tgtggatggc gaggctcttc caactcttgt tttgaacaag
    14101 attcgtggaa ccttcaacgt agtagcagtc aaggcacctg gttttggtga ccgtcgcaaa
    14161 gccatgcttg aagatatcgc catcttaaca ggcggaacag ttatcacaga agaccttggt
    14221 cttgagttga aagatgcgac aattgaagct cttggtcaag cagcgagagt gaccgtggac
    14281 aaagatagca cggttattgt agaaggtgca ggaaatcctg aagcgatttc taaccgtgtt
    14341 gcggttatca agtctcaaat cgaaactaca acttctgaat ttgaccgtga aaaattgcaa
    14401 gaacgcttgg ccaaattgtc aggtggtgta gcggttatta aggtcggagc cgcaactgaa
    14461 actgagttga aagaaatgaa actccgcatt gaagatgccc tcaacgctac tcgtgcagct
    14521 gttgaagaag gtattgttgc aggtggtgga acagctcttg ccaatgtgat tccagctgtt
    14581 gctaccttgg aattgacagg agatgaagca acaggacgta atattgttct ccgtgctttg
    14641 gaagaacccg ttcgtcaaat tgctcacaat gcaggatttg aaggatctat cgttatcgat
    14701 cgtttgaaaa atgctgagct tggtatagga ttcaacgcag caactggcga gtgggttaac
    14761 atgattgatc aaggtatcat tgatccagtt aaagtgagtc gttcagccct acaaaatgca
    14821 gcatctgtag ccagcttgat tttgacaaca gaagcagtcg tagccaataa accagaacca
    14881 gtagccccag ctccagcaat ggatccaagt atgatgggcg ggatgatgta agctttctat
    14941 agaaaacaac ttataaaaaa cacaaaagga gggaatgact aacccttctt tttataggct
    15001 ctttgtcaac tgtagtgggt tgaagtcagc taagctcgag aaaggacaaa ttttgtcctt
    15061 tcttttttga tattcagagc gat
//
LOCUS       DAVLMQ010000041        15028 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000041 DAVLMQ010000000
VERSION     DAVLMQ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.041"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            81..878
                     /locus_tag="VXF95_001602"
     CDS             81..878
                     /locus_tag="VXF95_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HEV1082123.1"
                     /translation="MISSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGVKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ANSIANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            1026..1148
                     /locus_tag="VXF95_001603"
     CDS             1026..1148
                     /locus_tag="VXF95_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine sulfhydrylase"
                     /protein_id="HEV1082124.1"
                     /translation="MTRDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
     gene            1170..2210
                     /locus_tag="VXF95_001604"
     CDS             1170..2210
                     /locus_tag="VXF95_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001231001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
                     /protein_id="HEV1082125.1"
                     /translation="MRKPGNIYTRITNPTTAALEGGVEALATASGMTAVTYTILAIAH
                     AGDHVVAASTIYGGTFNLLKEPLPRYGITTTFFDIDNLEEVEAAIKDNTKLVLIETLG
                     NPLINIPDLEKLAEIAHKHQIPLVSDNTFATPYLINVFSHGVDIAIHSVTKFIGGHGT
                     TIGGIIVDSGRFDWTASGKFPQFVDEGPSCHNLSYTRDVGAAAFIIAVRVQLLRDTGA
                     ALSPFNAFLLLQRLETSSLRVERHVQNAETIVDFLVNHPKVEKVNYPKLADSPYHALA
                     EKYLPKGVGSIFTFHVKGGEEEARKVIDNLEIFSDLANAADAKSLVVHPATTTHGQLS
                     EKDLEAAGVTPN"
     gene            2381..3655
                     /locus_tag="VXF95_001605"
     CDS             2381..3655
                     /locus_tag="VXF95_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HEV1082126.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMKQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHEALLAKDKEV
                     QLLENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3665..4543
                     /gene="truB"
                     /locus_tag="VXF95_001606"
     CDS             3665..4543
                     /gene="truB"
                     /locus_tag="VXF95_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HEV1082127.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4784..5086
                     /locus_tag="VXF95_001607"
     CDS             4784..5086
                     /locus_tag="VXF95_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HEV1082128.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQS
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5194..5832
                     /gene="udk"
                     /locus_tag="VXF95_001608"
     CDS             5194..5832
                     /gene="udk"
                     /locus_tag="VXF95_001608"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HEV1082129.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5960..7300
                     /locus_tag="VXF95_001609"
     CDS             5960..7300
                     /locus_tag="VXF95_001609"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HEV1082130.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEDLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEK
                     RMATAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLDSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7278..7490
                     /locus_tag="VXF95_001610"
     CDS             7278..7490
                     /locus_tag="VXF95_001610"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HEV1082131.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7487..8362
                     /locus_tag="VXF95_001611"
     CDS             7487..8362
                     /locus_tag="VXF95_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HEV1082132.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFE
                     TESIVSVVESLRING"
     gene            8355..9170
                     /locus_tag="VXF95_001612"
     CDS             8355..9170
                     /locus_tag="VXF95_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HEV1082133.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEA
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKGAVERAHSQFKNE"
     gene            9163..9594
                     /locus_tag="VXF95_001613"
     CDS             9163..9594
                     /locus_tag="VXF95_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1082134.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9601..11268
                     /gene="recN"
                     /locus_tag="VXF95_001614"
     CDS             9601..11268
                     /gene="recN"
                     /locus_tag="VXF95_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HEV1082135.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEEFMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLAAARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKVS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11270..11998
                     /locus_tag="VXF95_001615"
     CDS             11270..11998
                     /locus_tag="VXF95_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HEV1082136.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLD
                     APVDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12077..13900
                     /gene="lepA"
                     /locus_tag="VXF95_001616"
     CDS             12077..13900
                     /gene="lepA"
                     /locus_tag="VXF95_001616"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HEV1082137.1"
                     /translation="MNLEELKKRQGKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14059..14139)
                     /locus_tag="VXF95_001617"
                     /pseudo
     CDS             complement(14059..14139)
                     /locus_tag="VXF95_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14314..14790
                     /locus_tag="VXF95_001618"
     CDS             14314..14790
                     /locus_tag="VXF95_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1082138.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLMDFFTGNGHLEDLSKISEPEKLYAYIAEATA"
     gene            14828..>15028
                     /locus_tag="VXF95_001619"
     CDS             14828..>15028
                     /locus_tag="VXF95_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HEV1082139.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPG"
BASE COUNT         4489 a         2730 c         3533 g         4276 t
ORIGIN      
        1 ttttatgaaa tacagaaaac gcttcctaaa acctaaagtt tgtgatataa ttatcaagaa
       61 aaaagattta ggagtttatt atgatttctt cagaatttat ctcaaagatt gaatttgctt
      121 gcaataagaa agaaagtctt tatagtcaaa gcaaatttaa gtatgcgatt cgttcgatgt
      181 tcgcaggtgc atttttaacc ttcagtactg ctgcaggtgc agttggggct gacttgatta
      241 ataaaattgc accaggtagt ggacgcttcc tctttccatt cgtttttgct tggggcttgg
      301 cctacattgt ttttttgaat gccgagttgg tcacttcaaa catgatgttc ttgactgctg
      361 gtagtttctt aaaaaaaatc tcttggagaa aaacagctga gattttacta tactgtacct
      421 tgttcaacct tatcggagcc ttgatagcag ggtggggctt tgctcattcg gcagcctatg
      481 cgaatctgac acacgatagt ttcatctcag gtgttgttga gatgaagtta ggccgctcaa
      541 atgaattggt cttgcttgag gcgattttgg caaatatttt cgtaaatatt gcgattctgt
      601 catttatttt ggtcaaagat ggtggtgtca aactttggct tgtgttgtca gctatttaca
      661 tgtttgtatt cttaacaaac gagcacattg cggcgaactt tgcttctttc gcgattgtga
      721 aattcagtgt tgctgcgaat tcaattgcca acttcggtgt tggaaatatg cttcgccact
      781 ggggtgtgac tttcatcgga aactttatcg gaggaggcct cttgatgggt cttccatatg
      841 ccttcctcaa taaaaacgaa gatacttatg tagattaaga aaatgagcac gattgagtcg
      901 tgcttttttc attttcaaaa taaggtaata gctatttctt atatcaaaat atagaaaact
      961 gatatttgta aactataact caaggtgcta caatatcctt aataaaataa tatggaggtc
     1021 accttatgac tcgtgatttt aaatttgaaa ctctacaact acatgctggt caagttgtgg
     1081 ctccagctac taagtctcgt gcagtgccga tttatcaaac aacatttttt gtttttgatg
     1141 acacgtagga aggtgccgat ctgtttgcct tgaggaaacc agggaacatt tatactcgta
     1201 tcaccaatcc tacaacagct gcccttgaag gtggtgttga agcgctagca acagcatcag
     1261 gtatgactgc agtgacttat actattttgg cgattgccca tgctggtgac catgtagtgg
     1321 ctgcttcgac tatttacggt ggaaccttca atcttttgaa agaacccctt cctcgttatg
     1381 gtatcacaac aacctttttc gatattgata atttggagga agtagaagca gctatcaaag
     1441 acaataccaa gcttgtcttg attgaaacct tgggtaaccc cttgattaat attccagacc
     1501 tggaaaaact ggcagagatt gctcataaac atcaaatccc acttgtgtca gacaatactt
     1561 ttgcaacacc ttatttgatt aacgtcttct ctcatggcgt tgacattgcc attcactctg
     1621 tgactaagtt tatcggtggg catggtacaa ctattggagg aataattgtc gatagtggtc
     1681 gttttgactg gacggcttca gggaaattcc ctcaatttgt tgacgagggt ccaagctgcc
     1741 acaatttgag ctatactcgt gatgtgggtg cagcagcctt tattatagct gttcgagttc
     1801 aattgcttcg tgatacaggt gcagccttgt caccattcaa tgctttcctc ttgctacaaa
     1861 gacttgaaac ctcttcactt cgtgtggaac gccatgtaca aaatgctgag acaattgttg
     1921 attttcttgt caaccatcct aaggtagaaa aggtaaatta tccaaaactt gcagatagtc
     1981 cttatcatgc cttggctgag aaatacttgc caaaaggtgt cggttcaatc tttaccttcc
     2041 acgtcaaagg tggcgaggaa gaagcacgca aggtcattga taatttagaa atcttttctg
     2101 accttgcaaa cgcggcagat gctaaatcgc ttgttgtcca tccagcaaca accactcacg
     2161 gtcaattgtc agaaaaagac ctagaagcag caggtgtcac accaaactaa attcgtttgt
     2221 caatcggtct tgaaaatgta gaagatttga ttgaagactt gcgcttggcc ttggaaaaaa
     2281 tttaaagtaa aagaagataa acagtgggct tcgactcact gtttttgatt ttccctcagg
     2341 catgatataa tggttaaaga agtctagaaa gaggaacgat atgaacgaaa tcaaatgtcc
     2401 caactgtggg gaagtcttta cagtaaatga gagtcagtat gccgaactct tgtcccaagt
     2461 gagaacggca gagtttgata aggaactaca cgataggatg aagcaggaac tggccttggc
     2521 tgagcaaaag gccatgaatg agcaacagac taaactggct cagaaggatc aagaaattgc
     2581 gcaattacag agtcagatcc aaaactttga tacagaaaaa gaattggcca agaaagaggt
     2641 tgaacagaca agccatgagg ctctcttggc taaggacaag gaagtacagc tcttagaaaa
     2701 tcagttggct accttgcgtt tggagcatga aaatcaacta caaaagaccc tttctgacct
     2761 agaaaaagaa cgggatcagg ttaaaaacca actacttttg caggaaaagg aaaatgaatt
     2821 atctttggct tctgttaagc aaaactacga agcccagctc aaggcagcta gtgaacaagt
     2881 cgagttttat aagaatttta aggctcaaca atctacaaaa gcgattgggg aaagcctaga
     2941 acagtatgca gagagtgagt ttaacaaggt tcgtagtttc gcctttccaa atgcttactt
     3001 tgagaaggat aacaaggtct cttcgcgtgg gtctaaaggg gactttatct tccgtgagtg
     3061 tgatgaaaat ggagttgaaa tcatttctat catgtttgag atgaaaaacg aagcggacgg
     3121 aacagagaag aagcacaaga atgcagattt ttacaaggaa ttggacaagg accgtcggga
     3181 gaagaactgt gagtatgccg ttttggtgac catgcttgag gctgataatg actactttaa
     3241 cacagggatt gttgacgtca gtcacgagta tgaaaaaatg tatgttgttc gtcctcaatt
     3301 ctttatccaa ttgattggtc tcttacgtaa tgcggcgcta aattccctaa aatacaagca
     3361 ggagttggcc ttggttcgcg agcaaaatat tgacattacg cattttgagg aagacttgga
     3421 tgcctttaag ctagcttttg ctaagaacta taattcagct tcgactaact ttggaaaagc
     3481 tattgatgaa atcgacaagg ccatcaaacg catggaagag gttaagaaat tcctgactac
     3541 atctgaaaac caactccgtc tagctaacaa caaattggaa gatgtctctg ttaaaaaatt
     3601 gacccggaaa aatccaacaa tgaaagcgaa gttcgaagca ctgaaggggg agtagaaagc
     3661 aaaaatgaac ggtattatca acttaaaaaa agaagcagga atgacctcgc atgatgcggt
     3721 ttttaaactg cgtaagattt tgggaaccaa gaaaattggt catggcggaa ccttggatcc
     3781 ggatgtggtg ggtgttttgc cgattgcggt tggcaaggcg acacgcatgg tcgagtttat
     3841 gcaggacgag ggtaagatct atgaggggga aatcactctg ggttattcca cgacgactga
     3901 ggatgctagt ggggaagtgg tcgcagaaac ccctgttttg tctcccttgg atgaaaagct
     3961 tgttgatgaa gcgattgcta gcttgactgg gcctattacc cagattcccc ctatgtattc
     4021 ggcagttaag gttaatggtc gcaagctcta tgagtatgcg cgtgctggtc aggaagtgga
     4081 gcgtccagaa cgtcaggtga ccatttatca atttgagcga acaagtccga tttcttatga
     4141 tggccaactt gcccgattca cttttcgtgt aaaatgcagt aaagggactt acatccgtac
     4201 tttgtcagtt gatttgggtg aaaagcttgg ttatgcggct catatgtccc atttgactcg
     4261 tactagtgct gctggcttac aattagaaga cgctcttgcc ttggaggaaa ttgctgaaaa
     4321 agtagaggct gggcaattag attttctcca tcctttagag attgggacag gtgaccttgt
     4381 caaagttttc ctaactccag aagaggctac agaagttcgc tttggtcgtt ttattgagct
     4441 agaccaaacg gacaaagaac tggctgcctt tgaagatgat aaattgttag ccattctaga
     4501 aaaacggggc aatctctata agccaaggaa ggtttttagc tagatcgttt aggaataaaa
     4561 atcgggtgat agataacaat tgcttgataa aaccccatac taatagtaga atggttttgg
     4621 gaattataat attccaattg ttgcgagttg taggtactca aataatctat atagaaattt
     4681 agaggtgtga aatgaagcaa tttaaaattc tttcagataa atatttagag tccattacag
     4741 gttctggtgg gaacttaggc ccaggatttg gtgtgataat tccatgatgc gaaatgagtt
     4801 tcgagaaagg gtggagcaac ttcttcaaca aaaagaaata aatgaaaata gtgagttgag
     4861 tcacctgttt cgtcttgcta tacaaaattt agacagaaat gaaaaatacc aatcggtcat
     4921 ggccaatttg agtcaagggt tgtcacttta cctcatgacg catcattacc aggcacctaa
     4981 gtctgtcatt gattttggtt tatggattgc caaagctcct agccaggaaa gagggagact
     5041 ggctttcttg cagatgcttg ctcaaaccct acagggcttt cgttaaaact gtcgaacatc
     5101 agagggaaga ctctggtgtt ttttgctgat gagactataa attttgtaaa aaatgtgata
     5161 gaatagacga cggataaaat aacggaggat agcatgcaaa atagaccaat cattattgga
     5221 gtgacaggtg gttctggtgg tggtaaaacc agtgtttcaa gagccatttt atcgcatttt
     5281 cctgatgaaa agatttccat gattgagcat gattcatact acaaggatca gtctcatttg
     5341 acctttgaag agcgtgtcaa aaccaactat gaccatcctt ttgcctttga tacagacttg
     5401 atgatcgagc agattaagga attgttggca gggcgtccgg tggacatccc gacctacgac
     5461 tatacagagc atacacggag tagcaagacc tatcgtcagg agcctcaaga tgtctttatc
     5521 gttgagggca ttttggtctt ggaggacaag cgtctgcgcg atttgatgga tatcaagatt
     5581 tttgtggata cggatgacga tgtgcgcatt attcgtcgta tcaagcgtga tatggaggag
     5641 cgtggccgta gccttgatag cgttattaac cagtacttag gtgtggtcaa accaatgtac
     5701 caccagttta tcgagtcaac taagcgttat gctgatatcg tcattcctga aggggttagc
     5761 aataccgtgg ctatcgacct gttgacgacc aagattgcaa agattttgga agaagctcga
     5821 aacagcaaat aatcacatgt ggaggccttg cctccttttt ctatttttcc ctcataatgg
     5881 tacataaatg gagattttta ggcatatttt tggtataata atacccatga aagagcaagt
     5941 aaatgaatag taggtggaga tggaaaagta tttatcggta acaactttga ccaagtatct
     6001 gaaaatgaaa ttcgataaag acccatactt ggaacgggtc tatttaactg gtcaagtttc
     6061 caactttcgt aaacgaccta ctcaccaata tttctcccta aaggatgacc atgcagttat
     6121 tcaagcgacc atctggtctg ggatttatca gaaattaggg tttgacctgg aagaaggaat
     6181 gaagatcaat gtgattgggc gtgtacaggt ctatgaacca agtggtagct actccatcat
     6241 cattgaaaaa gctgagcctg atggggttgg ggcgcttgcg attcagtttg aacaacttaa
     6301 gaaaaaattg acagaagaag acctgtttca agaacgcttc aagcaagctc tgccccaatt
     6361 ttctaagaga attggtgtag taaccagccg tagtggagcc gttattcgag atattatcac
     6421 gaccgtcagc aggcgattcc caggtgttga catccttctt tatccgacca aggttcaagg
     6481 tgaaggggct gcggaggaaa ttgctagaaa tattgcgcgt gctaatcaac gggacgattt
     6541 ggatttgctc attattggtc gtggaggtgg ttctattgag gatctctggg cctttaacga
     6601 agaaattgtg gtacgagcta tttttgaatc tcgtttgcca gttatctcta gtgtggggca
     6661 tgagacggat gtgaccttgg cagattttgt ggcagatcga cgcgctgcaa cgccaacagc
     6721 ggcggctgaa ctggcaacac ctgtgaccaa gttggatgta ttaactcatt tgcaaaatca
     6781 ggaaaaacgg atggcaacgg cagtccgaaa tgttctatct aagaaacaag aggctttgaa
     6841 aaaatgcagt cagtctgtta tctttagaca acctgagcgc ttgtatgacg gttatttgca
     6901 acgcttggac caactgcaac tgcgtttgaa acaaagtttg cgaactcgga tttctgataa
     6961 caaacaatta gttcaagcaa gaactcatca attagtacaa ttatcacctg ttaccaaaat
     7021 ccaacgctat caagaccgtt taggacagtt ggacaagctc ttagatagcc aaatggcgtt
     7081 agtttatgac gccaaggttg ctgaggccaa gcgactttcg gaagctttgc tcatgttgga
     7141 tactagccga atcgttgcgc gtggttatgc tattgtcaaa aaagaagagt ccgttgtaga
     7201 ttcggttgag agtttgaaga aaaaagacca agtaacgctt ttgatgcgag atggtcaagt
     7261 agaattagag gttaaagatg tcaaaacaaa agaaatttga ggaaaatcta gcagaactgg
     7321 aaaccattgt ccaaagtttg gaaaatggtg aaattgctct ggaagatgcg attactgcct
     7381 ttcaaaaggg catggtcttg tcaaaagagc tccaagctac gctggacaag gctgaaaaga
     7441 ccttggtcaa ggtcatgcaa gaagacggaa cagaaagtga ttttgaatga aaaagcaaga
     7501 aaaattagct cttgtcgagt cggctttgga agatttttat ggagaccagc agtttgcctc
     7561 tagtttacgg gagtctgttc tctattctat tcatgctggt ggcaagcgta ttcggccttt
     7621 tctcttgtta gaagttctgg aagccttgca ggttaccatc aaacctgctc acgcgcaggt
     7681 agctactgcc ttggagatga ttcatacagg gagcttgatt cacgatgacc ttcctgctat
     7741 ggatgatgac gattatcgaa gagggcggtt aaccaatcac aagaaattcg gtgaagctat
     7801 ggccattttg gctggagatg ccttattctt agactcatat gccttgattg cgcaggcaga
     7861 tttgccaagt cagattaagg tggacttgat tgccaactta tcccttgctt caggtagtct
     7921 gggtatggtg gcagggcaag ttttggatat ggagggcgaa caccagcact tgtctttgga
     7981 agaacttcag actattcatg ccaataagac tgggaagtta ctagcctatc ccttccaagc
     8041 ggcagctatt atagctgaat tgtcacctga aatgcaggtg aagctgaaaa ctgtgggtga
     8101 attgattgga cttgcttttc aagtcagaga tgatgtactg gatgtgacag ctagttttga
     8161 ggaaatcggc aagacacctc aaaaggatct gcaggcagaa aaatcaacct atcctgccct
     8221 gttgggcttg gaagagtcca ttgccttttg taaccaaacc ctggatcaag ctaatgaaaa
     8281 attggaagaa attgcccagc agcttccctt tgaaacagaa tcgattgtaa gtgtagtaga
     8341 aagtttgaga atcaatggct aaggaaagag tggatgtact agcttataaa caggggttgt
     8401 ttgaaacgag agagcaggcc aagcgaggtg tgatggctgg cctagtcgta gcagtcctta
     8461 atggagaacg gtttgacaag ccaggagaga aaattccaga tgataccgaa ttaaaactca
     8521 agggggagaa actcaagtat gtcagccgtg gtggtttgaa actggaaaag gccttgcagg
     8581 tctttgattt gtcggtggat ggcgcgacta cgattgatat cggggcctct actggaggtt
     8641 ttaccgatgt catgctacag aatagtgcca agttggtctt tgcagtcgat gttggtacca
     8701 atcagttggc ttggaaatta cgccaagacc cacgagttgt cagcatggag cagttcaatt
     8761 tccgctatgc tgaaaagact gatttcgagc aggagccgag ctttgccagt attgatgtga
     8821 gtttcatttc ccttagtctg attttgccag ccttgcaccg tgtcttggct gatcaaggtc
     8881 aggtggtagc acttgtcaaa cctcagtttg aggcaggacg tgagcagatt gggaaaaatg
     8941 gaattattcg agatgctaag attcatcaga atgtccttga atctgtaaca gctatggcag
     9001 tagaggcagg tttttcagtc cttggcttgg acttttctcc catccaaggt ggacatggaa
     9061 atattgaatt tttagcgtat ttgaaaaaag aaaagtcagc aagcaatcag attcttgctg
     9121 agattaaagg agcagtagag agggcgcata gtcaatttaa aaatgaataa aaaagaaaga
     9181 cttgaaaaaa ttagaagatt ggtgacagat tatcaaatcg gcacgcaaga agaaattgta
     9241 gaacatttga aagaagcagg tatcactgcc actcaggcga cggtatcccg agatatcaaa
     9301 gagttaggta ttgtcaaaat tcctttgaga gacaacacct atgtctacga attaccaaaa
     9361 tcaatcgtaa aaagtctgca actggctgaa gacaatatcg aatcggctga attgatggat
     9421 aagatgatca atctccaagt tattccagga aatacggctt ttgtaaaagc tcagttaatc
     9481 gagacttttg cagacaagat ttttagctgt ttgactgatg atagctcgat tttagtcatt
     9541 gccagaagtg gaagtctagc agaggaaatc tttgaacaag taaaaaattg gtaggtctat
     9601 atgttacttg aaatttcgat aaaaaacttt gccattattg aggctatttc cctcaatttt
     9661 gaaaagggga tgactgtcct gactggtgaa acgggtgcag ggaagtcgat tatcattgat
     9721 gccatgaata tgatgttggg agctcgtgcg acgacagatg ttattcgtca tggtgcacca
     9781 aaggcagaga ttgaggggct tttctcagtt gagaatagtc gtcttttaca ggaaattttt
     9841 gatgagcaag gtttagaatt aggtgatgaa attatcatcc gtcgggaaat cttgcaaaat
     9901 ggtcgtagta tcagccgtgt aaatggtcag atggttaatc tgtctgtttt gcgagctatt
     9961 gggcaacatc ttgtagatat tcatggtcag catgaccatg aggagttcat gcgtccccaa
    10021 ctgcatatcc agatgttgga tgaatttggc gatgccgctt tttgggactt gaaagaaacc
    10081 tatcaaacga gttttgatgc ctatcggaaa atgcgcaagc aggttctgga agtcaagaaa
    10141 aaccaacagg aacacaaggc acgtatcgaa atgttggaat ttcaaatggc agagattgag
    10201 gcagcaaact tgcaggctgg agaagacttg gatctcaatc aagagcgaga taaactcctc
    10261 aaccacaaaa atattgcgga tacactgacc aatgcctaca gtatgttgga caatgaagat
    10321 ttttcaagtc tggccaatgt tcgttcagcc atgaatgaca tggaaagtgt cgaagagtat
    10381 gaccctgaat accgtgaaat ttcaagctct ctgtctgaga cctactatgt tttagaagac
    10441 attagcaaac gtttggaagc tatcattgag gaccttgatt ttgatggcaa tcgcctcatg
    10501 caggttgaga atcgtttgga cctccttcat actattactc gtaagtatgg tgggactgtt
    10561 gatgatgttt tgctttattt tgccaagatt acggaagaat acaatctctt gacaggcaat
    10621 aatctttcgt ctgaggacat ggaagcagag cttaagaagt tggaagtcaa tcttgtcaat
    10681 ttggcaggcc aacttgctgc tgctcgtcat aatttggctc agcaactcga agctgagatt
    10741 aaacaagaac tgcaagatct ttatatggaa aaagcccagt ttcaggttcg ttttagtaag
    10801 ggaaaattca gtcgtgaggg aaatgaaatg gttgagtttt atatttcaac caaccctgga
    10861 gaagacttta aacccttggt taaggttgct tctggagggg aattatctcg tctcatgtta
    10921 gccattaagt ctgccttttc acgtaaagaa ggcaagacta gcattgtctt tgatgaggtg
    10981 gatacgggag tttcaggtcg tgttgctcaa gctattgctc agaaaattca taaaattggt
    11041 cagcatggtc aggttttggc tatctcccat ttgccacaag taattgcgat tgcagattat
    11101 caattcttta ttgagaaggt tagtaatgac cattcaacgg tttcgactgt tcgtctcttg
    11161 acggtcgaag agcgagtgga ggaagttgcc aagatgttgg caggtgatga tgtgacagaa
    11221 gcagccctga cgcaagccag agaattgttg agaaacaggg agaaataaga tgacagatta
    11281 ttatgtaatt ggagatgttc acggaaaagc tgggatgctg gaagaccttc tcaaaacctg
    11341 ggatggtcag acccagttgc tctttctagg tgatttgatt gacagaggtg aggatagtca
    11401 ccgtgttctt gaaatggtca aggacttggt ggacaatcaa ggggctatct gtttgtctgg
    11461 aaaccacgag tatatgtttt tgacttggct agatgaccca gaagaaagtt atgaccatta
    11521 tcgtcgcaat ggtggagata caaccattaa ctctatccta ggtcgtccct tggatgcacc
    11581 agttgatgga gtagaagatg ccaagcgggt tgccgctgaa gcgtcagact tggtcgaatt
    11641 cattcgtcaa atgccatttg tagtagagac agacaagtat atatttgttc acgcaggtat
    11701 tgatttgact ttggacgact ggcatgaaac aacagattat aaaaaagtat ggcttagaaa
    11761 accattccac ggagctgaaa atcatactgg aaaaaccatt gtcttcggtc atacaccggt
    11821 ctatggtttg ttacagcaag aacgcggtac atctgagctt tggactacag aagatggcaa
    11881 gattggaatg gatggaggag ctgtttatgg tggtgtcctt cacgggattg tctttacaga
    11941 ccaaggaatg acagaacacc actttatcga aaatgacggc tttgtcgctg aagattagta
    12001 ctcctagcag ggtatggtct tgtcaaaata tcaaaaacaa tttataataa atagataccc
    12061 tgaaaggaag agaatcatga acttagaaga attgaaaaaa cgacagggga agatccgtaa
    12121 cttctctatt atcgcccata ttgaccacgg gaaatcaact ctagcagacc gcattttgga
    12181 aaaaacagag acggtttcaa gtcgtgaaat gcaggcccag cttttggata gcatggatct
    12241 agagcgggaa cgtggaatta ctattaagtt gaatgccatc gagttgaatt acactgcaaa
    12301 agatggggaa acttatattt tccacttgat tgacacacca gggcacgttg actttaccta
    12361 tgaagtttca cgttcgctag ctgcctgtga gggtgctatt ttggtggtcg atgcggctca
    12421 aggaattgag gctcaaactc ttgccaacgt ttatctggct ttggataatg atttggaaat
    12481 catgcctatc attaataaaa ttgacctgcc ggctgcagat ccggagcgcg tgcgtacaga
    12541 gattgaagat gtgattggtt tggatgccag tgaagcagtt ttggcttctg ccaaggctgg
    12601 tattgggatt gaagaaatcc tcgagcaaat tgtagaaaaa gtaccagcac caacgggtga
    12661 tgtgacggcg ccacttaagg ccttgatttt cgactctgtt tacgatgctt accgtggggt
    12721 tatcctccaa gtacgtgtca tggacggagt ggtcaaacct ggtgataaga ttcagctcat
    12781 gagcaatagt aagacctttg atgtggccga agtcggtatt tttacaccaa aagcggttgg
    12841 tcgtgatttc cttgcgactg gtgatgttgg ttacattgcg gcgtctatca agacggttca
    12901 ggatactcgt gtgggtgata ccgttacctt ggcaaccaat cctgcggcag aaccattaca
    12961 tggttataag cagatgaatc ctatggtctt tgcgggtctc tacccaatcg aatcaaacaa
    13021 gtacaatgac ctgcgtgaag cgcttgaaaa attgcaactg aatgatgcta gtcttcagtt
    13081 tgaaccagaa acatctcagg cacttggatt tggtttccgt tgtggatttc ttggacttct
    13141 ccatatggat gttatccagg aacgtttaga gcgtgagttc aatattgatc tcatcatgac
    13201 agctccgtct gttatttaca aagttaattt gaccgacggt gagtctatgg atgtgtctaa
    13261 cccatctgag tttccagacc caactaagat tgcgaccatt gaagagcctt atgtcaaggc
    13321 gcaaatcatg gtaccacagg agttcgtcgg agcagtaatg gagctagctc agcgtaagcg
    13381 tggggacttt gtgactatgg actatattga tgataaccgt gtcaatgtta tctatcaaat
    13441 tcctcttgct gaaattgtct ttgacttctt tgataaactt aagtcttcga cacgtggtta
    13501 tgcaagcttt gactacgaat tgtcagaata tcgcccatct aagctggtga aaatggatat
    13561 tcttctcaat ggagataagg tggatgccct cagctttatc gttcacaagg actttgccta
    13621 cgaacgtggg aaactcatcg ttgataaact caagaaaatc atccctcgcc aacaatttga
    13681 agttccaatc caagcggcta ttggacacaa gattgtcgct cgtactgata tcaaggccct
    13741 tcgtaagaac gtacttgcta aatgttatgg tggtgacgtt tctcgtaagc gtaaactcct
    13801 tgaaaaacaa aaagctggta agaaacgcat gaaatccatc ggatcagttg aagttccgca
    13861 agaagccttc ctcagcgtct tgagtatgga tgaagaataa gttatcagaa atgcctttcc
    13921 ttgttcacag gaaatttata taagaatcaa tagtaaagca ggcttagatg gtctgctttt
    13981 ttagttttta tactcttcga aaatctcttc aaaccacgtc agcgtcgcct tactgtatgt
    14041 atggttactg acttcgtcag tttcatctac aacctcaaaa ctgtgttttg agtaacctgc
    14101 ggctagcttc ctagtttgct ctttgatttt cattgagtat tagaacagaa aaaatgcttg
    14161 gagtatttgt ttgtgtgttt atttttatat aacaaactat aaacaaaaca aaaatataaa
    14221 aaaagagaca aaaaagaaca gaaagtaatt gacaacggtt tcatatagtg ttatacttat
    14281 ggcataaagt taatggaaag aagggaaaaa cttatggtat tagattattt ctttgacaaa
    14341 aaccttgtgt tttgcttaga agcggataat caagaacaac tctttgatca ggttgcaact
    14401 ttattggaag aacgagaaat tgtcactcca acttatcgtg aagctttgat cacgcgtgaa
    14461 aagtcatttc caactggttt agatatggaa tttctaggaa aggacttgcc aaatgtagcg
    14521 attcctcata cagatattgt tcataatcta gctgagaaag tggtggttgt tcgattagaa
    14581 aaaccagtaa cttttcacaa tatgatagct cctgataagg aagtagaagt atccttgctc
    14641 ttctttatca tcaataactc aagttcaagt caaacaaata ttctggctca gttgatggac
    14701 tttttcacag gaaatggaca tcttgaagac ctatcaaaaa tttccgaacc agaaaaactt
    14761 tatgcttaca ttgctgaagc aaccgcttaa tcttgtctat taaaaaataa aatcggagga
    14821 aatccaaatg attaaaattc ttgctgcctg cggtgcaggt gttaactcaa gtcaccaaat
    14881 taaaagtgct ctagaagaag aactttcaaa ccgtggttat gatgttcact gtgatgcagt
    14941 catggtgaaa gatgtaaacg aagaccttat gaaaggttac gatatcttta caccaatcgc
    15001 tgcaacagac cttggttttg aaccaggt
//
LOCUS       DAVLMQ010000042        14353 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000042 DAVLMQ010000000
VERSION     DAVLMQ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.042"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(178..1104)
                     /locus_tag="VXF95_001620"
     CDS             complement(178..1104)
                     /locus_tag="VXF95_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1082140.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLRI"
     gene            complement(1097..1789)
                     /gene="ftsE"
                     /locus_tag="VXF95_001621"
     CDS             complement(1097..1789)
                     /gene="ftsE"
                     /locus_tag="VXF95_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HEV1082141.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            complement(1807..2902)
                     /gene="prfB"
                     /locus_tag="VXF95_001622"
     CDS             complement(join(1807..2829,2831..2902))
                     /gene="prfB"
                     /locus_tag="VXF95_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HEV1082142.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            complement(3010..3666)
                     /locus_tag="VXF95_001623"
     CDS             complement(3010..3666)
                     /locus_tag="VXF95_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HEV1082143.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            complement(3973..4683)
                     /locus_tag="VXF95_001624"
     CDS             complement(3973..4683)
                     /locus_tag="VXF95_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082144.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQGTTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            complement(4683..5447)
                     /locus_tag="VXF95_001625"
     CDS             complement(4683..5447)
                     /locus_tag="VXF95_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082145.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKDKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            complement(5447..6403)
                     /locus_tag="VXF95_001626"
     CDS             complement(5447..6403)
                     /locus_tag="VXF95_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1082146.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            complement(6407..7276)
                     /locus_tag="VXF95_001627"
     CDS             complement(6407..7276)
                     /locus_tag="VXF95_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HEV1082147.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILAISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            complement(7544..8704)
                     /locus_tag="VXF95_001628"
     CDS             complement(7544..8704)
                     /locus_tag="VXF95_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HEV1082148.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEAAEVVKP"
     gene            complement(8806..9054)
                     /locus_tag="VXF95_001629"
     CDS             complement(8806..9054)
                     /locus_tag="VXF95_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HEV1082149.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            complement(9133..9723)
                     /gene="clpP"
                     /locus_tag="VXF95_001630"
     CDS             complement(9133..9723)
                     /gene="clpP"
                     /locus_tag="VXF95_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HEV1082150.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN"
     gene            complement(9897..10526)
                     /gene="upp"
                     /locus_tag="VXF95_001631"
     CDS             complement(9897..10526)
                     /gene="upp"
                     /locus_tag="VXF95_001631"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HEV1082151.1"
                     /translation="MGKIEVINHPLIQHKLSILRRTDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(10615..11082)
                     /locus_tag="VXF95_001632"
     CDS             complement(10615..11082)
                     /locus_tag="VXF95_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HEV1082152.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            complement(11101..11658)
                     /locus_tag="VXF95_001633"
     CDS             complement(11101..11658)
                     /locus_tag="VXF95_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HEV1082153.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            11783..12628
                     /locus_tag="VXF95_001634"
     CDS             11783..12628
                     /locus_tag="VXF95_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1082154.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            12687..13859
                     /locus_tag="VXF95_001635"
     CDS             12687..13859
                     /locus_tag="VXF95_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HEV1082155.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDDQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITELEAAESPLLTDFPHKALQGISLDDVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSNPI"
     gene            13874..14119
                     /locus_tag="VXF95_001636"
     CDS             13874..14119
                     /locus_tag="VXF95_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1082156.1"
                     /translation="MEQSPKKKKGTTLEHIILLRGVTPNGKNAIPKMSYLVDILTEAD
                     FQQVRTYIQSGNIILESNLALEEIREQVHTLLDFLQN"
     gene            complement(14116..>14353)
                     /locus_tag="VXF95_001637"
     CDS             complement(14116..>14353)
                     /locus_tag="VXF95_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1082157.1"
                     /translation="MKIYPQAQTPRKSSKLKPLTVEDKAYNHALSKERSKVENIFAKV
                     KTFKMFSTTYRNHRKRFGLRMNLVAGIINHELGF"
BASE COUNT         4247 a         3102 c         2640 g         4364 t
ORIGIN      
        1 attacacttt tttctaaaaa atttctagtg cgccaaattt caagttcaaa ttagccatca
       61 agaagtcttc tctgggggac ttctttggaa gctcttttct tctacgcatc tcttttcaaa
      121 aactcttgta gcaaaaaagg agattttaca atctcctcat aaaagcagct attttaccta
      181 aatcctcaag aatcggcgca tggatattcc tgatcccaat gaaccaatga aaaccccaat
      241 cacaaatagt agggcaatca tcaacggact aaataaatct ggactaatca tggatagatt
      301 ttgccctacc aacgatttgt tgacagattg gtaaacaatt tgataaacaa taaagaccaa
      361 aacagatggt gcgatagctc ccaataaacc gataaaggct ccttctaaca agaacggtcc
      421 acggatataa ctgtttttag ctccgaccaa gcgcatgatt tgaatttcgc gactgcggga
      481 aataatggta atacgaatgg tatttgaaat caagaaaact gcgataaaaa ttaacaaagc
      541 agcaatccct agtccccaaa cacggataaa tgaagctaac ttgaagagtc tttctgtatt
      601 ggcaccgcca tcttgaacct cagagacacc ttcaattttt ttagcatctt cggctatagt
      661 ttttacatca tttggagtgt ttgcctctac aatataggca tcatagagag gattggcatc
      721 tccttcaaag attttccagt tatctcccat tatctcggtt aatttttcat attgttcttc
      781 tttacttgaa aaggtaacac ttttaaccgt agacatgttc ttcaaagaat catatacctt
      841 gtggtagtca ttatttgtaa cagtttgacc ttctttttca attgtctgac tattatcttc
      901 cacatccttt cggatataaa ctactacacg gacattattt tcaatatctg tagctagttt
      961 cgctgtattg aaaataacag atgcaaatat tgccaccaag gtcaaagtaa tcatgactga
     1021 actgacagca gctactgtca tccaaccatt tcgtttcaaa ctttttaagg cttcaaataa
     1081 atggcgaaaa aatctactaa tcatcgtatc catactctcc ttttgattcg tcacgaacga
     1141 cacggccatt ttcaatggca atgacacggt ggcgcaaggt atttacaatc tggctattat
     1201 gagtcgccat caaaatagtt gtcccttgta ggttaatccg ttccaagaga ttcataattt
     1261 cccatgaatt atccggatcc agatttcctg ttggctcatc agctatcaat actttgggat
     1321 tatttacaat tgcacgcgca atcgcaattc gctgttgctc cccacctgag agttcatttg
     1381 ggaaagaacg aaccttatgc ttcaatccaa ccaagtccaa aacttccatc actcgtcttt
     1441 tgatattacg gcgattttcc ccgattactt ccatagcgta agcaatattt tcatagacag
     1501 ttttctttgg taacaattta taatcttgga agacaacccc aacactacga cgtagaagcg
     1561 ggacatcttt ctttttgatc ttaaccagat taaaaccagc aactgataga cttcctttat
     1621 cgatttttac ttcacgatac agagaacgaa taaaagttga cttccctgct cctgaaggtc
     1681 ctacgatgta agcaaattcc cccggttgaa cgctgaccga aacaccgcgt agagcagtcg
     1741 ttccgttgtc gtatttttta acgacatctc tcatttcaat aattgacatg tgagttcctt
     1801 tctatcttag ctaattcgcc acttgagata agcatcgata aaaccatcta ggtccccatc
     1861 cataacctta tctacctgag caacctcaaa gctagttcgg tgatctttta ccatagtata
     1921 aggcgtgaag acataagaac ggatttggct tccccaagtg atctcctttt tctcaccttt
     1981 gagagaatct acctccgcag ccttcttatc ttgctccatt tgatagagct tagcctgcaa
     2041 catcttcatg gcacgatctc tatttccata ctgggtacga tccactgttg attggacaac
     2101 aattccagtt ggaatgtggg ttaaacgtac acctgttgaa actttattga cgttttgtcc
     2161 accggcacca cctgaacgga aggtatccat cttgatatca tcttcacgga tttccacttc
     2221 aatagtatca tccaattctg gcatcacttc tacagatgtg aaagaggtat ggcgacgttt
     2281 ggcagagtca aatggtgaga ttcgcactaa gcgatgaaca cccatttctg acttgaggag
     2341 accataggca ttaggccctt caaatgataa agttaccgac ttaataccag cctcatcacc
     2401 tgcttggtaa tccaacactt ccactttaaa gcctttagca ttaccataac gagtatacat
     2461 acgaagcaac atatcacccc agtcctgcgc ctcagtacca ccagaacctg gatggatttc
     2521 caagatggca ttgttgtggt cataaggttc tgacaagagt agagtcatct cgtagctggt
     2581 cattatctta tcaagttcgg ctaactgcgc taccagttca tcatgcactg actcgtcttc
     2641 agccaaaaaa tccaataaaa tttcgacttc atcctgcaac tcttccatct tatggaaggt
     2701 attgtaagtg ttttttaatt catttaattc ttgcgacgtt ttttgggccg caatattatc
     2761 gttccaaaaa tcaggttctg tcatcttgtt ttccaagatg gcaatctctt cctctagccc
     2821 ttcgaggtca aagagacccc ctgaaagaag ctaatttttc acgatttgcg tcaattttct
     2881 gacgaattac tgaaatgtcc ataaatactc cttttttaca ttatttcatt atagcatatt
     2941 ttatcatttc tttccatctt tttctctaat ccccttttca tgaaaaaaga agcctttggg
     3001 cttcccttct tacaagactt ttgctgaagt gcgagcgatt tcttccactt gaataccatt
     3061 tgcttcaaat ttttctttca aggctggtaa atcaattgat ccatcgattt gcacttcgat
     3121 aatcacctta ccatccttac gcggaatatt gactgtatgg gagatattca aattttcttc
     3181 tacaatcaaa gaaacaattt ttccaagaac accaacttca tcttctgtaa caaagcgtac
     3241 acgaatccct tcttcgccat aacctgcaat ttcaagaaag gcttggaaaa cgtcacggtc
     3301 agtaataact ccgtatactt gatggttatc tacgacaggg agaatactaa tcttattttt
     3361 caacatcaga taagttgcat cttctagact agcatagcct gagacagtga caacatcgcg
     3421 aatcatgaca tcttttactt ttgtcttatt cagaagataa ttcatctcat agatagaaag
     3481 acttgttgct ttagatggac ttgcttgtgc aatggttccc tcagtcacca aaccaactaa
     3541 ttgatcattt tcgataacag gcagacggtg caaaccttgc tctctcatca aatctgctgc
     3601 atgagatact gttgtatctg gactaatata aactaccttg cgggtcataa aatctttaac
     3661 tgccatgaga cttctccttt tctattctta tccctattat acaatctttt tgcaaatcta
     3721 tcaaacgctt acatttcttt ttcgaaattc agaaaagtat gaataagcta gcaaaagagc
     3781 tctgaaatcg agttctgtga atgaaggtaa gaaacttttc attcgatttt ttcaattatt
     3841 agaaattcag ctttcaatgt agatgcagat ttgtttgcaa tctcaatcta ccgactaaaa
     3901 aggtcccccg gactatattg atgattactt cgtaatcttc atctgccgac taaaacaatc
     3961 cactggattg ttttagccac ctagatatgc ttttctgact tcttctgatg aggcgagttc
     4021 ttttcctgtt cctgatagga cgattttccc tgtttccagt acatatcctc ggtcagagat
     4081 tgcgagtgct ttattggcat tttgttcaat caagaggacg gttgttcctt gcttctgaat
     4141 atcttgaatg atatcaaaaa tctcttggat aaagattggg gcaagtccca ttgatggttc
     4201 atctaaaaga agaagttttg gtgttgacat aagagcgcgt cccatggcaa gcatttgttg
     4261 ttcccctcct gaaagagtag ctgcatcttg gttcttacgt tcttcaagac gaggaaagcg
     4321 tgagaaaacc ttcttcaagt ttgcttgatt ttcttcacga tttttcttta agaaagctcc
     4381 catttcaaga ttttccataa cagtcaagcc aggaaagacg tggcgtcctt ctggaacttg
     4441 tgaaagacca cctgccacga ttttctgagc tggcattttt tggatttctt gacctaaaaa
     4501 ttcaatcttt cctgaacttg gtcgaaccaa acctgacaag gtgcgaagaa tagttgtctt
     4561 acctgcaccg ttggcaccga taagggaaac aacttctcct tcattaactt caaagcttac
     4621 atcacggact gcttggatca taccgtaatg cacagaaaga ttttcaactt ttaacataga
     4681 cattaggctt cacctcctag ataagcttcg ataacgcgtt tattggtctt aatttcgtct
     4741 ggagttcctt gagcaattaa acggccatat tcaagtacgt agatacgttc tgttacttcc
     4801 atgaccagat tcatatcgtg ttcaatcaac atgattgtaa tcttaaattc atctttgata
     4861 cgacgaatta actcagtcaa ttcggctgtt tcctgtgggt tcatacctgc tgctggttca
     4921 tctaagaaga gaattttagg ttccgtagca agggcacgaa caatttccaa acgacgttgt
     4981 tgtccgtagg aaagattttt agcaagagtc tctgcatcac catctaaatc aaagattttc
     5041 aacaattcca aagctttatc ctttaattct ttttcactct tgtaaaaagc tggtaagcgt
     5101 aagaaactag taaaaacatg ctgtttgtga tggtttccaa aagcaatcaa aacattatct
     5161 aaaactgtta aatctttaaa gagacggata ttttggaaag tacgtccaag tcccaaagag
     5221 gcaatcttat aaggtgattt cccattcaaa aggtgaccat ctagggttac tgttccctcg
     5281 cttggttcat aaacaccggt caaaaggttg aaaagggtgg ttttcccagc tccgtttgga
     5341 ccgattaatc caaccagttc cccttcgttc aattcaagag tcacatctcc aacagctgtt
     5401 agaccaccaa aatgtttggt taactgtttt acttcaagta atgccattag ttttgttcct
     5461 ccttcttaga ttttttaaag aaacgtgata ggctcagttc ccatgttcca aggagtccac
     5521 ctggtctgaa aatcattacc aataccaagg ccaaagcgta aataatcata cgcacactag
     5581 caacatcttg gagaagcata ttcaaaattc ccagaacaat agccgaaaca atcgcacctg
     5641 taatggaacc gagtccacca aatacaacaa taatcaaaac gttgattgag ttgatgaagg
     5701 tgtaatcttt cggtacaaca gacccgataa atcctgcctg aagtgaccca gcaatacttg
     5761 cagtaatggc accaaagaca aaagcgatga ttttaatttt agtcgtatta accccaactg
     5821 actcagcagc gatttcatct tcacgaacag agagggttga acgaccaatt gggctacgca
     5881 agaagttcaa ggttgcaatg gttgtaatca cgacaaagaa gtaaaccatt tgccaagttg
     5941 taaagttagg aatccctaaa atacctgccg caccatttgt aaggcttcca ccattgatga
     6001 taaagatacg gataatttca gaaacaccta gagttgctac cgcaagatag tcccccttca
     6061 agcgcaaggt tggaatgccg acaagtaagg caactgctcc tgaaagcaaa gctcctacaa
     6121 gcatagctcc aaagaaggca ccgtaggttg gtgatttaga accaataata gctgctgcat
     6181 aggcaccaat cgccatgaaa ccagcatgac caagtgaaaa ttgtcctgaa aaaccaacga
     6241 ttaagttgag accaacagcc aaaataatat taattccaat ttgttgtaaa atctgtacat
     6301 agaatagatt aagtactccg actgaaacca gtacactaat caagctatag ccagctaaca
     6361 aaaggagtaa ccatagaata ttaactttta aattttcctt catcgcttac accttctctt
     6421 tcacattctt accaaggata ccagctgggc ggacaatcaa gatcaacaac aagattccat
     6481 aaacaatggc atcacggaaa tctgacatcc caaaggctgt cgcaaaggtt tccaatagac
     6541 caatcacaaa gccaccaaga gccgcaccag gaataattcc gataccacca agtactgcgg
     6601 caacgaaaga tttaagacct ggagtaaccc ccatcaaagg ctcaagagag ttataataaa
     6661 gagcaatcag aacaccagcc gcacccgcaa gagcagaacc caaagcgaag gtaaagctaa
     6721 tcgtacggtt tacattgatc cccatcaatt gcgccgcgtc gctatctact gatactgcac
     6781 gcatggcttt ccccatctta gtcttttgga caatgacttg taacaaaatc atcaaaatca
     6841 aggaaatagc caaaatcatt aactgcacat ttgttaagct aattggtccc aaatcatatc
     6901 gaactgtttg aatcgcttga gggaaggcac gggtattggc accaaccaga tagaccattc
     6961 catactccaa taggaaagaa accccaatag ccgtaatcaa aacagcaata cgagtagagt
     7021 ggcgcaaagg tcggtaagca agaaactcaa tcacgacacc aagaatagct gtcgctagca
     7081 tagctacaat aagcgctaca aagaaattca tttggaaaga attgatcaag aaataaccga
     7141 taaaggctcc catcatataa atatcaccat gggcgaagtt gatgagcttg ataattccgt
     7201 aaaccatggt atatcctagg gctaacagcg cgtaaacact acctagaatc aaaccattta
     7261 cgagttgttg gagcataaga ttcactcttt ctatttataa ttccgagggt tttccctcac
     7321 tttttgatag gttcttatac tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag
     7381 gttgctcaaa gcactgcttt gaggttgtag ataagactga cgaagtcagt cacatatata
     7441 atccaaggcg acgttgacgc agtttgaaga gattttcgaa gagtattaaa tatcgaaaca
     7501 gggagtgagt caaaggctca ttccctattt caacattttt ctattatggt tttacaactt
     7561 ctgctgcttc aactttacca ttgttcatgg tcatcatgta agcagttttg actgtgttgt
     7621 ggtctgcatc gaagcttgtt tgaccagtta caccttcaaa atcttttgtt ttagcaaggt
     7681 tatccttgat ttcacctgaa tttttagcac cttttgctgc gtttgctaca aggtgaactg
     7741 aatcataagc caaggctgca aatgttgaag gctcttcatt gtacttagca cggtaagcgt
     7801 caaggaaggc tttagcttta gctgaaactt ctacagtagt tgagaagcct gagataaagt
     7861 agatgtttga tgctttttca gcagttgctt gttgtacaaa ctcctcaccg ttgaatccat
     7921 caccaccaac gattggtttg tcaattccca tgccacgcgc ttggtttaca atcttaccag
     7981 cctcattata gtaaccagga acaacgatag catcaaagtc tttccctttc atttttgtaa
     8041 gggctgcttg gaagtctgtg tcacctgcta cgaaagtttc atctgcaacg atttcaccct
     8101 tgtatgactc gcggaaagat ttggcaatcc ctttagcata gtcactggca ttgtcagtgt
     8161 aaagaacaac tttcttagca tttaattttt cagaaacata gtttgagata atttttcctt
     8221 ggaagctatc ttggaaagtt ccaataaaga ggtaatcttg acctttagtc aatccatctt
     8281 gagtcgcact tggtgagatc aatggaacac ctgcttttgt agcgttcgct accgcagctg
     8341 cagtcgcacc agatgtcgca ggtcctacga ctgctgatac tttagattgg gttacaaggt
     8401 tagttgtaac tgaagcagcc tcagctgttt cagacttatt atctttatcg actacttcga
     8461 tttgttttcc atcgatacca cctgcggcat tgatttcatc aacagccaat tgggcacctt
     8521 tttgttcagc tgttccgtat gcagctaaag aacctgattc ttcaaagtta aacccgattt
     8581 taattgtctt ttcctctact gagttaccag cagtgttgac tgctccagac ttcacttctc
     8641 cacaggctgc aagaagtgct acacttgcaa gcgccacaaa cgatagggca aattttttct
     8701 tcatcttttt gtctccttat ttcttaaata gtctgttaag aatataccga attatcagaa
     8761 aattgtcaat gttttccttg agcttttttc gatgataacg ttttcctatc gataaagatt
     8821 gcccacaaag ggtgtttcca actcttggat atgacaaacc ctaacttttt taataaattt
     8881 ttccttgctc aagcgtccga ccaattgctc cacttcttga gttggaacat agagttgtaa
     8941 gtaacgatgt ttcttggaat gataggtaat atctccataa tcctgcagtt ttttggcatc
     9001 acgattatag taaagataga taatcaagcc agagcgattg actttttcaa acatgataaa
     9061 tcctctttct aagaaatctc tccctattat accaaaaaaa gcaaacccag tcgagtttgc
     9121 cttctatcat cattagttca atgaattgtt ggccataatt tcatcaataa agccatattc
     9181 aagtgtttcc tgggcgctca tccagttatc acgttctgca tctgcatgga ctttttccat
     9241 tgactgacct gaattttcag ccaagatttt ttccaaggta ttacgagttt tgagcaagtg
     9301 ttctgcagcg atagccatat cagtttgttg ggtaccacca cctgtaccgc ccattggttg
     9361 gtgaatcatg tattcagcat ttggaagcat gaaacgtttg ccttttgctc cacttgatgc
     9421 gatgacagtc cccatagatg cagccattcc cataacaatg gtttggacat ctgccttgat
     9481 aaagttcatg gtatctacga ttgccaaacc agctgaaaca gaaccacctg gtgtattgac
     9541 ataaaggtaa atatcttttg tactatcttg ggcatccaag aaaagcaatt gggcaataac
     9601 agagttagcc atattgtctt caaccggacc tgtcagcata atgatgcggt ctttgagaag
     9661 acgtgagtaa atatcgtaag aacgttctcc acggcttgtt tgttcaataa ctacaggaat
     9721 cattcatttc tccttttgag ttttaatttt gttggtcaaa tgactgaaga taagactatt
     9781 ataatatctt ggtcaaaaaa ggtcaaattt ttgctctgct ttcattagac agaaacaaaa
     9841 acccaacctc ctttcgtgac tggaaatact tttccaagtc attcttcttt tcgatcttat
     9901 tttgtaccga acaagcggtc tccagcatct ccaagacctg gaacgatata accgtgttcg
     9961 ttcaaacgtt catccaaggc tgctgtaaag atttctacat ctggatgagc ttcttgaagg
    10021 gcttttacac cctctggagc agatacaagg cagacaaatt tgatatttga tgcgccacgt
    10081 tttttaagag aatcaacagc caagattgct gagccacctg ttgccaacat tgggtctact
    10141 acaaaaattt gacgttggtc aatgtcctca ggcaatttca ccaagtattc aactggttga
    10201 agtgtttctt catcacggta cataccgatg tggccaactt tagcagctgg aaccaagctc
    10261 aagagaccat caaccatccc gatacctgca cgcaagattg ggacgatggc caatttctta
    10321 cctgccaatt gtttttgaac tgtttttgta attggtgttt cgatttccac atcttctagt
    10381 ggaagatcac gaagtacttc ataccccatc aacattgcaa tctcatctac tagctcacga
    10441 aaagcttttg tagaagtatc tgtacgacgc aagattgaca atttgtgttg aatcagtggg
    10501 tgattaataa cttcaatttt tcccattttt ggaattcctt ctttcaattt attcttctta
    10561 ttataccaaa aaacggttta aaaatctttc taaaccattt atttttgata atttttacat
    10621 tagatcagcc tctttaagag ctgtctgtac tgtctcaagt ggtaaatggg tcaattctgt
    10681 ccctttttct tgataaaggt attgggcgta gtcgtccatt cggtactggt tgatataaac
    10741 cacacgcttg cagccgacct gaagcaattg ttttgtacag ttgagacaag gaaaatgggt
    10801 tacataggct gtaaagcctt tgggaacacc acgctcagca ccttgaagga tagcattgac
    10861 ctcagcgtga agggtgcgaa cacagtggcc ttcaatgacc aaacattcgt gatcaataca
    10921 atgctcagtc cctgacaccg aaccattgta accagtggaa ataaccttat tatcttttac
    10981 cagaatcgcg cccactttag cacgtttaca agtggaacga ttcgcaatta gtagggcttg
    11041 ggctgcaaaa tactcatccc aggccagtct tttttcagtc atctcttttc tcctttttct
    11101 ctatttttta aaaaatggta aacctaaatc tgcaatcttt tcagctggta ccttcatgcc
    11161 atccttgatc cattttagaa ggacagagac gatggctgag ctccagaagg aatgaagata
    11221 agagctgaca ccttttgatt tcccatggta tttttctaga aattcctgca tggcttggac
    11281 aaagattttt tccagatggt aatccaaggc caattgaatc actctagctt cctttctggc
    11341 ctcccggaaa aggtgaaccc aaaccaaata aaggtctgtc tttaaatcgt aatgatgcag
    11401 ctgttccata atattgtgga cagttcgttt aaagacgctc tctaaaattt cctctttgga
    11461 gtcataattg cgataaaagg ccgcacgcga aacacctgca cgtttgacca attcagaaat
    11521 actaatcttg gtcagttcct ttttttccaa gagttgcaag agggctgttt caatggcttc
    11581 tctggttaat aaattggatt cttggtttga ttttctgaga ttttcaagag acttttcaga
    11641 gattctacgt tcagacataa cattttcttt ctacttgtca caacagacgg atgatgcttt
    11701 tgtttcaagg gttttcatga tataattgta aaaaaagaca gaacctttgt caatgtataa
    11761 ctgacaaaga tggagaattt ctatgacttg gaagattatt gctgactctg gttgtgatta
    11821 tcgtcaactg ccaacaccag ctattaacac aacctttgta agtgtcccct taaccattca
    11881 agtagctgat caggtctttg ttgatgacgc cagtctcgat attgaccaaa tgatggaaac
    11941 catgtatgca actgcagaag cttcaaaatc ggcttgtcca agcccagatg actatttgcg
    12001 agcatttgaa ggtgccaaaa acattttcct agtaaccatc acaggtaccc tttctggcag
    12061 tcacaatagt gctcaactag caaagaatat ttatctggaa gaccatcctg acactaagat
    12121 tcatgtgatt gatagtttat ctgctggtgg tgaagttgac ctactcgtag aaaaattgaa
    12181 tgacttgatt gaccagggct tgtcttttga agaagtggtt gaagctatca ccgcctatca
    12241 agaaaaaact aagttgctct ttgtcctagc caaagtcgat aacttggtga agaacggccg
    12301 tttgagcaag cttatcggta cggtcgttgg ccttctcaac attcgtatgg tcggaaaagc
    12361 tagtgaaact ggaactctcg aattgctaca aaaagcaagg ggatcaaaga aatcagttca
    12421 agctgcctat gatgagttag taaaagctgg atatgctggt ggccgtattg tcatggccca
    12481 acgcaataac gaaaaatgtt gtcaacagct ctcagagcga atccgtgaaa ccttcccaca
    12541 agcggatatt aaaattctac caacctctgg tctctgcagt ttctatgcag aagagggcgg
    12601 tttgctgatg ggctatgaaa ttgattaatt gcattcttga caagaggtga ccatcatctc
    12661 ttgttttttt gtggtacaat agagctatga aacattttga tactattgtc atcggtgggg
    12721 gacctgctgg tatgatggct acgatttcca gtagctttta tggacagaaa accctcctca
    12781 tcgaaaaaaa tcggaaactt ggaaaaaaat tagctgggac tggtggggga cgttgcaatg
    12841 tgaccaacaa tggtagctta gacaacctgc tagctggaat tcctggaaac ggacgctttc
    12901 tttacagtgt tttctcccag ttcgataatc atgacatcat caactttttt acagaaaatg
    12961 gtgttaaact taaggtcgaa gaccacggac gcgtctttcc agccagtgac aagtctcgga
    13021 ctattatcga agctttggaa aagaaaatca ctgaactagg tggtcaagtt gctactcaaa
    13081 tagaaatcgt ttctgttaaa aaagtagatg accagtttgt ccttaagtca gcggatcaaa
    13141 ccttcacttg tgagaaactc attgtcacaa caggtggtaa gtcttatcct tcgactggtt
    13201 cgactggttt tggtcacgag attgctcgcc attttaagca taccatcacc gagcttgagg
    13261 ctgctgaaag tcctttatta acagattttc cacataaagc cttacaaggg atttctttgg
    13321 acgatgtgac cctaagttat ggtaagcatg tcatcactca tgatttactc tttacccact
    13381 ttggtttgtc aggtcctgct gccctacgca tgtctagctt tgtcaaaggt ggggaggttc
    13441 tctcactcga tgttttgcct caactttctg agaaggactt ggttacattt ctagaagaaa
    13501 atcgggaaaa atccttgaaa aacgctttaa aaaccttgtt accagaacgc ttggccgaat
    13561 tttttgtaca aggatatcct gaaaaagtca aacagctgac tgaaaaggaa cgagaacaac
    13621 ttgtccagtc cattaaagaa cttaaaattc ctgtaactgg aaaaatgtcc cttgcaaagt
    13681 cctttgttac caagggtgga gtcagtctca aggaaatcaa tcctaaaacc cttgaaagta
    13741 agctggtacc tggcctccac tttgcaggcg aagttatgga tatcaatgcc cacacgggtg
    13801 gctttaacat cacttctgct ctctgtaccg gctgggtggc gggatcaaat ccaatctaaa
    13861 tatacattac taaatggaac aatcccccaa aaaaaagaaa ggaactactt tggaacatat
    13921 tatcttgcta aggggagtca ctcctaatgg aaaaaatgct atccctaaaa tgtcttatct
    13981 agtagatatc ttgacagaag ctgattttca acaagttcga acttatattc aaagtggaaa
    14041 tattattctt gaaagtaact tagctctcga agaaatacga gaacaggttc atactctatt
    14101 agacttcctg caaaactaaa atcctagttc atgattgata atgccagcaa ccaaattcat
    14161 tcgtaatccg aagcgtttac gatgatttcg ataggttgtt gaaaacattt taaacgtttt
    14221 tactttggca aagatgttct caaccttgct tctctccttg gatagcgcat ggttataggc
    14281 tttatcttca actgttagcg gcttgagttt gctggattta cgtggagttt gtgcttgagg
    14341 atatatcttc atg
//
LOCUS       DAVLMQ010000043        13669 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000043 DAVLMQ010000000
VERSION     DAVLMQ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13669)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13669)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13669
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.043"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(833..1681)
                     /locus_tag="VXF95_001638"
     CDS             complement(833..1681)
                     /locus_tag="VXF95_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HEV1082158.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            1833..2111
                     /locus_tag="VXF95_001639"
     CDS             1833..2111
                     /locus_tag="VXF95_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082159.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            2113..4176
                     /locus_tag="VXF95_001640"
     CDS             2113..4176
                     /locus_tag="VXF95_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1082160.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGAGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLIRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(4254..5510)
                     /locus_tag="VXF95_001641"
     CDS             complement(4254..5510)
                     /locus_tag="VXF95_001641"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HEV1082161.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQDLDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            5652..8114
                     /locus_tag="VXF95_001642"
     CDS             5652..8114
                     /locus_tag="VXF95_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1082162.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMTKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYRMLREKGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNEHFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSRARR"
     gene            8179..9090
                     /locus_tag="VXF95_001643"
     CDS             8179..9090
                     /locus_tag="VXF95_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HEV1082163.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSLVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVSVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            9320..10018
                     /gene="dapD"
                     /locus_tag="VXF95_001644"
     CDS             9320..10018
                     /gene="dapD"
                     /locus_tag="VXF95_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HEV1082164.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEHDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGAVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            10086..11216
                     /locus_tag="VXF95_001645"
     CDS             10086..11216
                     /locus_tag="VXF95_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HEV1082165.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFAGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITDTAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            11228..11767
                     /locus_tag="VXF95_001646"
     CDS             11228..11767
                     /locus_tag="VXF95_001646"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HEV1082166.1"
                     /translation="MKSELRKQVLHEMKALSQEQKQAIDQALTERILQHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMDFVVYDPQQLVKTAFALLEPQ
                     GDLEVVDVSQIDLIHVPGLAFTTDGYRIGYGGGYYDRYLEHFSGRTLSTVHPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            11751..12428
                     /locus_tag="VXF95_001647"
     CDS             11751..12428
                     /locus_tag="VXF95_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HEV1082167.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGM"
     gene            12430..12516
                     /locus_tag="VXF95_001648"
                     /pseudo
     CDS             12430..12516
                     /locus_tag="VXF95_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(12684..13631)
                     /locus_tag="VXF95_001649"
     CDS             complement(12684..13631)
                     /locus_tag="VXF95_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HEV1082168.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     EQQAKIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNK
                     VKESSKAIVDFHLQKGLAYDVKDSDEKFKDKATLETNVKEITKQIDFIKKVDETFKQE
                     NLEETLKSLNDLVDKYQKQIELLKKEEEKAAEKAKESSSQSNSSSGASNESYNGSSNS
                     NVDYSSSEQTNGYSNNYGSQSYSGSGDSSTNGGSSEQYSSSNSNSGVNNGYYKKYKNI
                     GADGHVSYTYDNESNGDVFDENWNYLGNTGGGIAEPPQR"
BASE COUNT         3883 a         2451 c         3044 g         4291 t
ORIGIN      
        1 gtcaagaaaa atatgctatt atgttaaaaa aatatttttc aaaatataaa tggacggatt
       61 tattttggat tttatttgtt attttgacct gcctctatat tggtaaccat gatttgttta
      121 ctctcaatca tcaagaattc tcttttcgtg gtagcttttg gggtttggta ctgaccttat
      181 atcacttatt gttcattgat aagtttgtaa tttcgaatcg aaaataaaga ttagagctat
      241 gcttgactgt gtacttttag gattgatttt ggaggaagat tttgtctcta ttatttatta
      301 ttttaaattt atttattttg tataagatct attctttgag gcgggaaaaa tcgaaatact
      361 tgatttatac ggcctatatc atatttgggg taaatgtagt atatggtatt caatggttat
      421 taaaagaact gatttcaact atttcccctt aatgcgtatg gaaactataa caaaacgcat
      481 aagattaagg tttgtgtacc tgttcttata cgtttttgtc atattgaaga ttttcggtaa
      541 gttttctact tttgcgaagt ctagtttata ctcaatgaaa atcaaagagt aaactagccg
      601 taggttgctc aaagtacagc tttgaggttg cagataaaac tgacgaagtc agctcaaaac
      661 atggttttga ggttgtagat gaaactgacg aagtcagctc aaaacatggt tttgaggttg
      721 tagatgaaac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
      781 aagtcagtaa ccatacgtac ggcaaggcga cgttgacgtg gtttgaagag tattagaatg
      841 ctttcccaac cagaatctct gcttcgatgg taatctctgt cagttggctc cagtcaatct
      901 tgctctggtc aacgtgaaag aggagaggag tcatactgag tagggcttgg agttgttctg
      961 ctgtgatagt cttagtcaga gaggcagttt gactagatag gatggtaaag tgttcctgga
     1021 aatgctcctt gatatcttgg ttagaatact ccttgtttgt cagctggtcc tgtactcttt
     1081 gacggatttc tttgaggtga ttttcagttg ggataacctt tatcaagata ccgtctttgg
     1141 ataaaacgcg acgaaattct ccatagttgg caggtgagaa gatatcaagc agaatatcca
     1201 tgttagcgtc ttttatagga aggcgtgcca agtcgccaac gaaccaattg actgcccagt
     1261 tgggttcact tttagcagcg atttggactg aatctttgga gatgtcaaag gcatagaaag
     1321 ttttttcaga gtgactttct tgtagtttgc gagaatagaa tccttcacca caaccgatat
     1381 ccaaaattgt tgtggtagtt tttgagcttg caagcaagtc agatacagca tctaagatag
     1441 cttggtaaaa gccggcttct aggatttgtt gacggttttg aaaattttcc ttgtcatagt
     1501 tagcagattg cttgatttga ggtgctagat tgacatagcc aaatttcgcc aagtcaaaag
     1561 aatgacggtt gcagcacttg aaattagtct ctaacagagt cagattttct tgacagatag
     1621 gacaggcaaa ggcagtcgca gaagcaaaac gctgaagttt gggcttgaga tttgtattca
     1681 tagtttaagt gtatcaaaag aggcaaatga aagcaacttt aggaataagt agatgggaga
     1741 ttcagtagaa ataaaactaa ttctccaatt tatagaatga aattgctttt atatctaaat
     1801 tgctatataa taatgataag gaggaaataa gtatgttaaa agaagtatta accgttgcaa
     1861 aagttgcgaa aaaatcttca ttatttttgg gtggtgtcgc atttggtacc cttggtttga
     1921 aaatcttagc aagtaaggaa gctaaaaaag gttattctaa agctttggct aaggcttaca
     1981 agttgaaaga cgagctagat gcatctgttt ctgttgtgaa gcaacatgga gacgatgtct
     2041 tgcaagatgc caaatatttg tacgagcaag agaaaaaaga agagcaatta gatagcctta
     2101 taggtgaata atatgtcttt taaagtgcta catagaggat accaacatat ccgactatca
     2161 tcttcttttt cacttacctt ggatattcaa gactatcttc gttccttggc gagagatgaa
     2221 aaggggattg agtctatcca gttttacatg gatcaacagc actttactct acgcataaaa
     2281 gaaggctttt ctgtattaga taatgcagaa gcctttttaa aaagaattga taaagggaaa
     2341 gtttctgagt tgatgactct tcccattcgt agagaagaga gtgcttattc tattgtttca
     2401 ggtgcagcgg ttaagcgtgt actttttcgt agttttgtgc cgtatcctat tcgctatata
     2461 tggacttgtt atcaggcttt gggttatatt agagaagcct atcaaacact agcgcgtaag
     2521 gaactaacga tggaagtctt ggactgttcg gctattttat tgtccttgtt tatgaaccaa
     2581 tccaagacag ctagcaatat catgtttatg cttgatttgg ggaatcattt agatcagtgg
     2641 tccttgaaaa aaactgcaac agatttagaa cagagtcttc ttgcaaaaga gagcgatgta
     2701 ttcctagtac agggcgatac ggttgttagt ataaagagtt ccgatgttca aataggagat
     2761 gtcttgatct tatctcaagg aaatgaaatt ctgtttgatg ggcaagtagt ttcaggttta
     2821 ggtatggtca acgaaagttc cttgacagga gagagttttc cagttgaaaa aagagagtct
     2881 gatttggttt gtgcaaatac agtattagaa actggagagt tacgcattcg tgtaacagat
     2941 aatcagatga acagccgtat tttacagctg attgagttga tgaagaaatc tgaagaaaac
     3001 aagaaaacga aacaacgcta tttcatcaag atggcggata aagtcgtcaa atataatttc
     3061 ttgggggctg ggctgactta cctattgaca ggttcttttt ctaaggctat ttctttccta
     3121 ttggtcgatt tctcctgcgc tttgaaaatc tctactcctg tagcttattt gacagttatc
     3181 aaggaagggt tgaaccgtga aatggtgatt aaggatggag atgttctgga gaaatatctg
     3241 gaagttgata ctttcttgtt tgataagaca ggaacaatca caactagtta tcctatagtt
     3301 gaaaaggtgt taccttttgg agactatagt gaggaagata ttctcagaat cagtgcctgt
     3361 cttgaggaac acatttatca tcctattgct aatgccatcg tcaagcaagc tgagatagag
     3421 ggaattgaac atgaggaaat gcatgggaaa ctccaatata tcgcaagcaa ggggatcaaa
     3481 tctcatatag atggccaacc agttcttatt gggaattatg tcttgatgca ggatgagcag
     3541 attcatatca gttcagaaca aaatgcttta attgaagagt acaagagtca ctacaatctc
     3601 ttattcttgg cttatcaaaa tgaattgatt ggaatgttct gcattcatac tcctttgaga
     3661 aaagaagcaa aaacagcctt ggataaactt aaggcacagg ggaaaaaatt gattctggca
     3721 acaggagaca ccttgattag gacagaggaa ttagtcaaag atttgccctt tgatcaggtc
     3781 tatacagact tgaaacctga tgggaaattt gagttagtag agaaactgca gaaagcaggt
     3841 cacactattt tgatggttgg agatggattg aatgactcag cggctttaac tctatcagat
     3901 atcggtgtgg tgatgaatga gagtgcagat atttctaagc agatgagtga tatcttattg
     3961 ttagataatc gtttggattt cttccaagag ttggattcgt tatcatcatc tttgcaaaca
     4021 ctcatcaaga aaaatattca agataccgtt gtcgtaaata gtagtttgat tggcttcggc
     4081 ttatttaatt ggctcagtcc ttcaaatctc tctatcttac ataatctaac aaccttgcgc
     4141 attgtcctgc gtagcctgtc tattaaaaat agatagatga gagttattaa cagcaaaaag
     4201 gagttacctt tctcgaggtt aactcctttg tttatagata aatgttgaat agtttagtaa
     4261 gtcaatacaa agtatttttt cttcccacga cggataacag tcagttcatt ttctaactta
     4321 tcagcgtcac tcaagacata gtcaaggtct tggatgcggt cgccgtttac gtagatggct
     4381 ccgttttgga cgtcttcacg ggcttggcgt tttgagttaa ctataccaga tgagacgagc
     4441 agttccacga tattgttgtt ttcgtctgcc tgtacttggt agtttggcac accacgaagt
     4501 ccttgtttga gctctttgac agaaaggttt ttgatgtttc ctgcaaagag ttgctcagtg
     4561 atgttaagtg cttctttgta ggcttcttct ccgtgaacaa gtgtaacaac ttcacgagcc
     4621 aagacttttt gagccaagcg ttcgtgtggc gctgcttcaa attgtttacg aatatcttca
     4681 atctcatcaa gtgacaagaa agtaaagatt ttcaagaagc gaacagcgtc agcgtccatc
     4741 acgttcatcc agaattggta catttcgtat ggagaagtct tttcgggatt gagccagacg
     4801 gcatttcctt ctgatttacc aaatttttta ccagttgcat ctgtgattag tggaacagtg
     4861 ataacgtgac cagtcttgtc cgccttacga cgaagcaatt cggtaccagc tgtcatattt
     4921 ccccactggt cagaaccacc gatttgaaga gtgacattat ggtcttggtt aaggacgaag
     4981 aagtcgtacc cttgcatgat ttggtaagcg aactcagtgt aagaaattcc tgtttcgatc
     5041 cgttttttaa cagattcctt actcatcatg tagttgaccg tgaagtattt tccaatatca
     5101 cggaggaagt caatgaagct gatgctgcca aaccagtcgt agttgttgac catgacagcc
     5161 ttgttttcgc cattttcaaa gtcaagaaaa cgagaaagtt gtccttggat agacttgacc
     5221 cagccatcta ctgtgtcttt tgtttggaga ctacgttcag catctttgaa ggacggatct
     5281 ccgatgagac ctgtagcacc gccaacgagc gcataaggtt tgtgacctgc tagttgcaag
     5341 cgacgacttg tcaagattgc gacaaggtgg cctaggtgaa ggctgtcagc agttggatcg
     5401 tagccagtat aataagaaac ttgaccttct tctagggctt tacgcaaagc ttcttcatca
     5461 gtcgtttgaa atatcaaacc acgctctttt agctcatcaa aaatgtgcat gtgtcttttc
     5521 tcctttttaa aattattgtt tctacctatt gtatcacaaa cttgggcaat agcctagcag
     5581 aatagggaag aaagtggcta ttttattgaa aatttccctt ttgtggtata atagataaag
     5641 tgaggaaatc catgcaaaat caattaaatg aattaaaacg aaaaatgctg gaatttttcc
     5701 agcaaaaaca aaaaaataaa aaatcagcta gacctggcaa gaaaggttca agtaccaaaa
     5761 aatctaaaac cttagataag tcagccattt tcccagctat tttactgagt ataaaagcct
     5821 tatttaactt actctttgta ctcggttttc taggaggaat gttgggagct gggattgctt
     5881 tggggtacgg agtggcctta tttgacaagg ttcgggtgcc tcagacagaa gaattggtga
     5941 atcaggtcaa ggacatctct tctatttcag agattaccta ttcggacggg acggtgattg
     6001 cttccataga gagtgatttg ttgcgcactt ctatctcatc tgagcaaatt tcggaaaatc
     6061 tgaagaaggc tatcattgcg acagaagatg aacactttaa agaacataag ggtgtagtac
     6121 ccaaggcggt gattcgtgcg accttgggga aatttgtagg tttgggttcc tctagtgggg
     6181 gttcaacctt gacccagcaa ctaattaaac agcaggtggt tggggatgcg ccgaccttgg
     6241 ctcgtaaggc ggcagagatt gtggatgctc ttgccttgga acgcgccatg actaaagatg
     6301 agattttaac gacctatctc aatgtggctc cctttggccg aaataataag ggacagaata
     6361 ttgcaggggc tcggcaagca gctgagggaa ttttcggtgt agatgccagt cagttgactg
     6421 ttcctcaagc agcattttta gcaggacttc cacagagtcc tattacttac tctccttatg
     6481 aaaatactgg ggagttgaag agtgatgaag acctagaaat tggcttaaga cgggctaagg
     6541 cagttcttta cagtatgtat cgtacaggtg cattaagcaa agacgagtat tctcagtaca
     6601 aggattatga ccttaaacag gactttttac catcgggcac ggtcacagga atttcacgag
     6661 actatttata ctttacaact ttggcagaag ctcaagaacg tatgtatgac tatctagctc
     6721 agagagacaa tgtctccgct aaggagttga aaaatgaggc aactcagaag ttttatcgag
     6781 atttggcagc caaggaaatt gaaaatggtg gttataagat tactactacc atagatcaga
     6841 aaattcattc tgccatgcaa agtgcggttg ctgattatgg ctatctttta gacgatggaa
     6901 caggtcgtgt agaagtaggg aatgtcttga tggacaacca aacaggtgct attctaggct
     6961 ttgtaggtgg tcgtaattat caagaaaatc aaaataatca tgcctttgat accaaacgtt
     7021 cgccagcttc tactaccaag cccttgctgg cctacggtat tgctattgac cagggcttga
     7081 tgggaagtga aacgattcta tctaactatc caacaaactt tgctaatggc aatccgatta
     7141 tgtatgctaa tagcaaggga acaggaatga tgaccttggg agaagctctg aactattcat
     7201 ggaatatccc tgcttactgg acctatcgta tgctccgtga aaagggtgtt gatgtcaagg
     7261 gttatatgga aaagatgggt tacgagattc ctgagtacgg tattgagagc ttgccaatgg
     7321 gtggtggtat tgaagtcaca gttgcccagc ataccaatgg ctatcagacc ttagctaata
     7381 atggagttta tcatcagaag catgtgattt caaagattga agcagcagat ggtagagtgg
     7441 tgtatgagta tcaggataaa ccagttcaag tctattcaaa agctactgcg acgattatgc
     7501 agggattgct acgagaagtt ctatcctctc gtgtgacaac aaccttcaag tctaacctga
     7561 cttctttaaa tcctactctg gctaatgcag attggattgg gaagactggt acaaccaacc
     7621 aagacgaaaa tatgtggctc atgctttcga cacctagatt aaccctaggt ggctggattg
     7681 ggcatgatga taatcattca ttgtcacgta gagcaggtta ttctaataac tctaattaca
     7741 tggctcatct agtaaatgcg attcagcaag cttccccaag catttggggg aacgagcact
     7801 ttgctttaga tcctagtgta gtgaaatcgg aagtcttgaa atcaacaggt caaaaaccag
     7861 ggaaggtttc tgttgaagga aaagaagtag aggtcacagg ttcgactgtt accagctatt
     7921 gggctaataa gtcaggagcg ccagcgacaa gttatcgctt tgctattggt ggaagtgatg
     7981 cggattatca gaatgcttgg tctagtattg tggggagtct accaactcca tccagctcca
     8041 gcagttcaag tagtagttct agcgatagca gtaactcaag tactacacga ccttcttcaa
     8101 gggcgagacg ataattctct aaatgaagtg gccaatcaat ggattgccac ttttttcctt
     8161 tcgtgttaca ataagggtat gaatcagtat cagaaaaaga ttgttaacgg aaaaatttat
     8221 tcgctcctat ccggcttaat atggggaatc tgtggaattt taggagagta cttctttact
     8281 cattatcagg tgtcttcggg ctggattacc tctatgcgtt tgacactggc agggagtctt
     8341 gtactcattt ggtctgcaat acaattaaaa tcgcaagtgc tagatatttg gcgagacaag
     8401 aaaaattacc tgcccttttt agcctatgct attttgggga ttttttcagt tcagtatttt
     8461 ttctatctct gtgtagaata ctcaaatgct acgacagcaa ctattttaca gtttattagc
     8521 cctgtcttta tcctctttta taatcgcttg gtttatcaaa aacgagcgtc aaaaagcgct
     8581 gttttctatg ttttggttgc catgctgggt gtttgcttga tggcgacaaa gggagatctc
     8641 tctcagttat ccatgacgcc gctagctctt ataacaggtt tgctgagtgc catgggtgtt
     8701 atgtttaatg ttatcttgcc ccaacctttt gctaagcgtt atggttttgt tcctacggtt
     8761 gggtggggga tgattttggc aggtttgttt agcaatgtcc tctcgccggt ttatcagctt
     8821 tcctttactc ttgatatttg gagtatcttg atttgcctca ttatcgcttt ctttggaacg
     8881 gcttttgctt ttttcatttc catgaaggct gtgtccttgg tttctccttt ggtggtttcc
     8941 gttatcagtg ccagtgaacc tctctcttct gctctcttga gtgttttgtt cttaggatta
     9001 gtagtggatt ggtccctcct tctagctata gccttgatta ttttacccat gatatttttg
     9061 tctatagaag aagcgaaaga aagtagataa aaagtctttt cttaattcta aaagtgtgct
     9121 atactagaat agtcaataaa acacggggag atagttgtga agagtgtttt taggttgtat
     9181 cggtaggggc ttgcttttac cgacagcacg ttttatctca caaccctaaa aaatcatacc
     9241 taaaaacaga caaaaaggtt tcaaatttga ggcctttttt ggtagaatag gtatcattat
     9301 aacgaaccag gaggcaccta tgactgctac aaaaatgaac gctcaagaaa ttatccaatt
     9361 tatcgccaat gctgaaaaga aaaccagtgt caaagtaacc tttgaggggc aactcgcaac
     9421 tgctgtgcct agctctgttg tcaaactagg aaatgtccta ttcggagact ggaaggacgt
     9481 ggctccgctt cttgaaggtt tggtagaaaa tcaagattat gttgtcgagc acgatgctcg
     9541 taattctgca gttcctttgc tagataagcg tgctatcaac gctcgtatcg agccaggtgc
     9601 tattatccgt gaccaggtgg aaattggtga caatgctgtt atcatgatgg gagctgttat
     9661 caatatcggt gctgaaatcg gtgctggaac catgattgac atgggtgcca tccttggtgg
     9721 ccgtgctatc gttggaaaaa atagccacgt tggtgcaggt gcagttttgg caggtgtgat
     9781 tgagccagct agtgctgaac cagtccgtgt cggagacaat gttcttatcg gtgctaatgc
     9841 agtggttatc gaaggagtcc aaatcggtag tggttcagtt gtcgcagcag gagctattgt
     9901 tacccaagat gtcccagaaa acgtggtagt agcaggtgtt ccagctcgta ttatcaaaga
     9961 aattgatgcc caaactcaac aaaaaacagc gctagaggat gcgcttcgta ccttgtaatt
    10021 gtaaaagtaa aaaagaggcg gaaccctttt tccagcctct ttctgctata tcggaggaca
    10081 gatagatgtt agatttgatt cagactagac gagatttaca ccagatacca gagattggct
    10141 tggaggagtt caagactcag gcttatttgc tggatgtgat tgagaaattg actacgggca
    10201 aggattttgt tcaaattcgt acttggcgga cagggatttt ggtctacctg cagggaagtc
    10261 agccggagcg aaccattggt tggcggacag atattgatgg cctgcctatc gtcgaacaaa
    10321 caggtctacc ttttgcttct caacaccaag gtcgcatgca tgcctgtggt catgattttc
    10381 atatgaccat tgccttaggc tgtcttgagc gcgcccttga ggagcaaccc aagaataatc
    10441 tgctctttct atttcagcct gctgaagaaa atgaagctgg tggtatgctc atgtatgagg
    10501 acggtgcttt tggagattgg ttgccaaacc aattctatgg tctccatgtt cgtccagatt
    10561 tgaaagtcgg ccagattgcg actaatactc atacactctt tgcaggaact tgcgaggtga
    10621 agatccgttt caaaggcaaa ggtggccacg cagcttttcc tcatgaagcc aatgacgcct
    10681 tggtggctgc tagttacttt gtgacccaag tgcagtcagt tgttagccgc aatgtcaacc
    10741 caatcgaggg agcagtggtg accttcggcg tttttcaagc tggaaccacc aacaatgtca
    10801 tcacagacac agctttttta catggaacta ttcgtgcctt gacacaggac atgagtctct
    10861 tggtgcaaaa gagggtaaaa acagttgcag aaggggttgc agctgccttt gatatggaag
    10921 tcgaagtgga actcaaacaa ggtggatacc tacctgttga gaacaatcca gccttggcgc
    10981 gtgaactgat ggacttcttt gacgaaaaag acggaatcga gttgattgat atcgaacctg
    11041 ctatgacagg cgaggacttt ggttatctcc tttcaaaggt tgatggcgtg atgttttggc
    11101 taggtatcga tagtccctac gctcttcatc accctcaaat gagtcctaag gaagaagtct
    11161 tagctattgg ggtggctgcg gtgtctagtt tcctgaaaaa gaaggcagca gaatagaggg
    11221 cttgtatatg aaatcggaat tacgcaagca agtcttgcat gaaatgaagg ctttatctca
    11281 agaacaaaaa caggctatag accaagcttt aaccgagcga attttacaac acccctttta
    11341 tcaagaagcc aaggtcatcg caacctacct ctctttttct catgagtttc aaacgcggga
    11401 actgattgag caggcgctga aggacggcaa gaaggtttta atacccaaaa cttatcccaa
    11461 ggggcgcatg gactttgtag tctatgatcc gcagcagttg gtaaaaactg cctttgcctt
    11521 actggagcca cagggagatt tggaagtggt ggatgtatct cagattgatt tgattcatgt
    11581 tcctggcctg gcttttacga cggatggata tcggattgga tatggtggag gttattatga
    11641 ccgctatctg gaacattttt ctggtcgtac tttgagtacg gttcatcctt gtcaaattca
    11701 ggactttata cctgaaaacc atgatattcc tgttcaggag gtattaattg atgaaggaaa
    11761 tctttgatag acgttaccct gtgacgagtt tcttcctctt agtgacggcc ttggtatttt
    11821 tactaatgtt ggtcactgca ggcggaaact ttgacagggc agatacatta tttcgatttg
    11881 gagccatgta tgggccagct attcgcctct ttcccgagca ggtttggcgt ctcttgtctg
    11941 ccatttttgt tcatattggg tgggaacatt tcattgttaa tatgctttca ctttattatc
    12001 ttggaaggca ggtagaggag attttcggct ctaagcagtt cttttttctc tatctcttat
    12061 caggaatgat gggcaatctc tttgtttttg tatttagtcc taaatcctta gcagcaggcg
    12121 cctctacctc tctttatggg ctatttgccg cgattattgt tcttcgctat gcaactcgca
    12181 atccttatat ccaacagcta gggcaatcct atctgacact ttttgtggtt aacattattg
    12241 gaagtgttct gattccagga atcagcctag caggccatat cggtggtgca gttggtggcg
    12301 catttctagc agttatcttt ccagttagag gagaaaaacg gatgtataac accagccaga
    12361 gattaggagc ggtagtcttg ttcgtaggac tcgccatttt gcttttctac aagggaatgg
    12421 gaatgtgacg actaatactc aatgaaaatc aaagagcaaa ctaggaagct agccgcaggt
    12481 tgctcaaagc actgctttga ggttgtagat gaaactgacg aagtcagtaa ccatatatac
    12541 ggtaaggcga cgctgacgtg gtttgaattt gattttcgaa gagtataata tgtaaacttg
    12601 aataagaaaa aagctactta aaaaatgagt agcttttaat gtgttttgga accattcgaa
    12661 acaacacagc tctaaaatag ttattagcgt tgtggaggtt ctgcaatgcc tcccccagtg
    12721 tttccaagat aattccaatt ttcgtcaaac acatctccat tgctctcatt gtcgtaagta
    12781 taacttacat gtccatcagc accaatattc ttatattttt tatagtagcc attatttact
    12841 ccgctgttgg aattgctaga tgaatattgt tctgatgatc caccatttgt tgaactatct
    12901 ccagaaccag aataactttg acttccataa ttattcgaat atccattagt ttgttcagat
    12961 gaactataat ctacatttga attggaagat ccattataag actcattaga agcaccacta
    13021 gaagaattac tttgactaga agattccttt gctttttcag cagctttttc ttcttctttc
    13081 ttcaaaagtt cgatttgttt ttgatattta tcaacaagat catttagaga tttaagagtt
    13141 tcttccaaat tctcttgttt aaaagtttca tcaacttttt tgataaaatc aatttgtttt
    13201 gtaatttctt tcacatttgt ttcaagagtt gctttatctt taaacttctc atcagaatct
    13261 ttaacatcat aagccaaacc tttttgcaaa tgaaaatcta caattgcttt agatgattct
    13321 ttgactttgt tattaagata gtctttacct gcatcggttt taagtgaagt ttcagatagt
    13381 tcttttaatt tagaaataga ttcatctgaa gatgcatcaa atgattcaaa tagtttatca
    13441 acttgttctt tgtctgattt gctatctttt tctaattgta caatttttgc ttgttgttct
    13501 gcttgttgtt ctgcttgttg ttggttatat gaataccatc caaaccctaa taccaataca
    13561 acaccaactg caactgatga aatgattact tttttattgt tttcgataaa ttctacaaat
    13621 ttgttctcca taatctttta ctttgatagt gtccgcaatt actttaaaa
//
LOCUS       DAVLMQ010000044        13455 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000044 DAVLMQ010000000
VERSION     DAVLMQ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13455)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13455)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13455
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.044"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            18..908
                     /locus_tag="VXF95_001650"
     CDS             18..908
                     /locus_tag="VXF95_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082169.1"
                     /translation="MDNTKVIEWLNYCDQNDIKPWLWDFKNCYSSELTADNISNFLKY
                     KNGELVNPSTFCITKQVGSNADCDKEALPLYNVLGWQHSERDIIRGETLNSYITTFTQ
                     AITNDPNYKEICKKIGVNLNEYLNKQYPILHHNKNYQNFKMIQKNLKEFEAFAKLTHT
                     IGNFTVLPHWMNTGRYNFSKDYWDITMLSLQEWLTNLSPQAWKNFIDTYYLQPYVDNN
                     YQTEVFWETHNYEYIYPKKTEDFSIFLKRVNERIEERGKFIIKQICDKLNKKDFHFYK
                     EIENMDKIKYSNEFEQERKQ"
     gene            905..1375
                     /locus_tag="VXF95_001651"
     CDS             905..1375
                     /locus_tag="VXF95_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082170.1"
                     /translation="MTRVYKSVRLAYEAKVWIDELIQEKERKIQELNKEDFLDKLEKT
                     LLKNHYDELNGLSFNIILKASIGSVIEESYRNTKHYPIDKWQKLRQQMERDVKNVNPN
                     LETTVTPRIYLDEDVLAGLDDFRYVLMKEDCATRLPRLSYIIKLVVYSYWKEQH"
     gene            1462..2130
                     /locus_tag="VXF95_001652"
                     /pseudo
     CDS             1462..2130
                     /locus_tag="VXF95_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476106.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            2090..3271
                     /locus_tag="VXF95_001653"
                     /pseudo
     CDS             2090..3271
                     /locus_tag="VXF95_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014678337.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(3534..3926)
                     /gene="rpsI"
                     /locus_tag="VXF95_001654"
     CDS             complement(3534..3926)
                     /gene="rpsI"
                     /locus_tag="VXF95_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HEV1082171.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVVGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(3946..4392)
                     /gene="rplM"
                     /locus_tag="VXF95_001655"
     CDS             complement(3946..4392)
                     /gene="rplM"
                     /locus_tag="VXF95_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HEV1082172.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            4748..5065
                     /locus_tag="VXF95_001656"
     CDS             4748..5065
                     /locus_tag="VXF95_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HEV1082173.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            complement(5110..5922)
                     /gene="folK"
                     /locus_tag="VXF95_001657"
     CDS             complement(5110..5922)
                     /gene="folK"
                     /locus_tag="VXF95_001657"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HEV1082174.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQVNLKQAIDKLRARGIHILKESSVLET
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(5965..6519)
                     /gene="folE"
                     /locus_tag="VXF95_001658"
     CDS             complement(5965..6519)
                     /gene="folE"
                     /locus_tag="VXF95_001658"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HEV1082175.1"
                     /translation="MDTQKIEAAVKMIIEAVGENVNREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            complement(6500..7822)
                     /locus_tag="VXF95_001659"
     CDS             complement(6500..7822)
                     /locus_tag="VXF95_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HEV1082176.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVIHI
                     GGTNGKGSTIAFLKNMLEKLGLRVGVFSSPYLIHYTDQISINGESIPEARLEALMVDY
                     QSLLEGGVASNFQETTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEVIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADH
                     HKEILFTCIKTKALEDMLDLLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            complement(7824..8804)
                     /gene="folP"
                     /locus_tag="VXF95_001660"
     CDS             complement(7824..8804)
                     /gene="folP"
                     /locus_tag="VXF95_001660"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HEV1082177.1"
                     /translation="MVKSLEGVTDMSTKVNHAKTAICGIINVTPDSFSDGGQFFALEQ
                     ALQQARKLIAEGASMLDIGGESTRPGSSYSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTWKSQVAEAALAAGANLVNDITGLMGDEKMAEVVAKAGAKVVIMFNPVIARPQHPSS
                     LIFPHFGFGQAFTEEELANFEKLPIEDLMETFFERALARANQAGIAQENILLDLGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHKMAVEIASAIRLADEAENLDLKQYK"
     gene            complement(8899..9606)
                     /locus_tag="VXF95_001661"
     CDS             complement(8899..9606)
                     /locus_tag="VXF95_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082178.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVAGLSIVVLALFIMGARKTKLASFNFSFFRAKDLARLGLSYLVIVGSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSIVLSWTAYKTQRLEMSILLHMIVNGVAF
                     CLLALVVIMSRTLGISV"
     gene            complement(9659..11077)
                     /locus_tag="VXF95_001662"
     CDS             complement(9659..11077)
                     /locus_tag="VXF95_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HEV1082179.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHAMIWILDALFILNYISMAL"
     gene            11267..12079
                     /locus_tag="VXF95_001663"
     CDS             11267..12079
                     /locus_tag="VXF95_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HEV1082180.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            12418..13437
                     /gene="adhP"
                     /locus_tag="VXF95_001664"
     CDS             12418..13437
                     /gene="adhP"
                     /locus_tag="VXF95_001664"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HEV1082181.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIATADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKV
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLTLAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         4295 a         2828 c         2472 g         3860 t
ORIGIN      
        1 atagaatagg tagaattatg gataacacaa aagttattga atggttaaat tactgtgacc
       61 aaaacgatat caaaccatgg ttatgggatt ttaaaaattg ttactctagc gagttaaccg
      121 cagataatat ttcaaatttt ctaaaatata aaaatggaga actcgtaaat ccttccacat
      181 tttgtatcac aaaacaggtt ggtagtaacg ctgactgcga taaagaggca ctcccacttt
      241 ataatgtttt aggttggcaa cattccgaga gagatataat aagaggtgag accttaaatt
      301 cttatataac tacatttact caagctatta ccaatgaccc gaattataaa gaaatttgta
      361 aaaagattgg agtaaactta aatgaatatc taaacaagca gtatccaatc ttacaccata
      421 ataaaaacta tcaaaatttc aagatgattc aaaaaaacct aaaagaattt gaagcattcg
      481 caaaattaac acatacaatc ggaaacttta ctgtattgcc tcattggatg aatactggac
      541 gatacaattt ctcaaaagat tactgggata ttacaatgct ttctcttcaa gaatggctta
      601 ctaatttatc tcctcaagca tggaaaaatt ttattgatac atactatctt caaccctatg
      661 ttgataataa ctatcaaaca gaggtatttt gggaaactca taactacgaa tacatttatc
      721 ccaagaaaac cgaagatttc tccatcttcc taaaaagagt caatgaacgg attgaggagc
      781 gcgggaaatt catcattaaa caaatatgcg ataaactaaa taaaaaagat ttccatttct
      841 ataaggaaat tgaaaatatg gataaaatta aatactcaaa tgaatttgaa caagagagga
      901 aacaatgact agagtatata aaagcgtccg ccttgcgtac gaggcaaagg tatggataga
      961 tgaattgatt caagaaaaag aacgtaaaat tcaagaactt aataaagagg attttctaga
     1021 taaacttgaa aaaacacttc ttaaaaatca ctatgatgaa ttgaatggtc tttcatttaa
     1081 tatcattcta aaagcctcaa tagggagtgt catagaagaa tcctatcgaa atactaaaca
     1141 ctatccaatt gacaaatggc aaaagctacg tcagcagatg gaaagggacg taaaaaatgt
     1201 taatcctaac ttagaaacca cagttactcc ccgtatttat ctagacgagg atgtgcttgc
     1261 tgggcttgat gattttcgct atgttttgat gaaagaggac tgtgctacta gactacctcg
     1321 tcttagctac attatcaaac ttgttgtata ttcctactgg aaagaacaac actaatctaa
     1381 tcagttctac tgtttagatt ttcatttctt taaaatgtat atttgttgta ctactaataa
     1441 atctagaaaa ataggtaatc tatgtttaaa ttaaagaaag tcgctgactt aaaaagaaat
     1501 tatatcattt caactaacaa attaaaggta actcattggt caatattaag cctctctatc
     1561 tgcattatgc ttactattat tgcaaatatt agagcccctg accttattaa aatcccttta
     1621 cttattctag taggatttgt catatacaaa tttcatcgtc aattaaaata ttttagatat
     1681 aatttagatt attacctaat tatcagagaa agcttattgt atgtattaca tacaaaccgc
     1741 ctttatacaa cacataaaga tagctcagga tatgaaaaaa tctctaggag cgcaatctta
     1801 caatacgagt tagacaaaca aaaggggcat atctttatca aagctctgat tactggtgat
     1861 gaatttagta aaagggtaca atcacttgat gatgttcttg ctggagtact cgaactggaa
     1921 ctagaataca aaattattcg tcctagtttt atggaatacc atttctatta caagaaacct
     1981 gacaggttag ttcttcaatc tcacaaccag aagcaagaga tagataacct taatatagat
     2041 ttaggatacg gtgtgaatta taatcctatc aagtgtcctc atattctagt tgccggaggt
     2101 acaggaagcg ggaaatcagt atttatatct ttaaggaaat cactttgtta aacgctataa
     2161 aacaagaaag gaggctaaag aagctgaatt agaaattcta acaaagatac atcaacttga
     2221 aaatggagag gatatcccac tccttaaaac tagtgatatt cttttctctg agttctttaa
     2281 taatatttgg tgggattcat acaaagctgg tcaaacaact tcaacaacta aacccccaac
     2341 acaagttact attgataata ctgaaatagt tttcaggaag cacatcttac caatgttcgg
     2401 taattattca atcaattttc tgaatcagaa taagcaaatc gtactaaact taatgactgc
     2461 taaagctgaa gaatatgcta atttcaaggt tattcgaagc tatgtaaact caattttcga
     2521 ttgggctgaa gaattagaat acattgaatc aaatagatta tcaaaaagca taaaacgtat
     2581 taaagcaagt aaaaaaataa agctagaaga agctaaggat gaggaagatt tgtatctatc
     2641 tagtgaagaa ttacaagatt ggtttgatgc ttttagagaa gatttggaga acgacaaatt
     2701 atcactaaaa gattatgtcc tattctttac aacctttatt ttgagcgata gaaaatcaga
     2761 atcctatgct ctacattgga aaaacataga cttggcaaac gctcaaattg gcttaaggca
     2821 tgcacttgac aaatataaga atgtaaagtc aacaaaagga aataagaaaa cgattttttc
     2881 aattcctagt taccttgtat cacttctttc agaatggaaa aaacagcaga aatatgagtt
     2941 agcgaaattt ggtataatgc aaacatccga tcaactagtc tttacctata tagatacgaa
     3001 aggtaatgta aatagccctc tacacgttga ttatctcaat aacaaaatga actctgtaaa
     3061 aagacgacac ccaaagttaa aacacgctac acctcataaa ttacgacata caggagcgac
     3121 acttgctaaa aaggcaggaa tgagcttaga agccatttct gaagtattaa ctcatagtga
     3181 tacaattaca actaaaactt atgttaatgc ttcaaacata gttccattat ctgctggaca
     3241 agttgcctac caacatctta aaaacaagta gggtaatttt agggcaaatt ttagggaaaa
     3301 cttttttaga aagtatagaa aaaagcaccc atagggcaaa cctttgagtg ctttgaaaca
     3361 ttgatataat cgtattgatt aacgttttga ggcaactgac cttgtcaggt tgcagccaca
     3421 tttgtaagcg actaaagtcg caacaactgt gtcaattgca ccaatttagt aagaaagtat
     3481 aaaaaaagaa caccccgaaa ggtgctctgt ataagtatag taattctttc gaattaacgt
     3541 ttactaaatt gtgatgcttt acgagctttc ttaagacctg gtttcttacg ttcaacttta
     3601 cgtgagtcac gtgtaagaag tcctgcgcgt ttcaatgaat cgcggaagtc tgggtctact
     3661 tgaagaaggg cacgagcgat accgtgacgg atagctcctg attgaccagc gtatccacca
     3721 cctacaacgt taacgaaaac gtcgtatgaa cctacagttg aagtaactgc gaatggttgg
     3781 ttgatgacaa gacgaaggtc agcgtgtggg atatactctt caacatcttt tttgttaaca
     3841 gtgattttac cagttcctgg aacaaggcga acgcgtgcaa cagcgttttt acgacgtcca
     3901 gtacctgcat attgtgcttg tgacatactt tatttgttcc tttccttaga taagtcctga
     3961 aatgtcaaga acttctggtt gttgtgcagc atgagtgtgc tcagctccaa caaatacttt
     4021 caacttcata ccttgagcgc gtccaagtgt attgtgtgga agcatacctt taactgattt
     4081 ctcaatcaaa cgtactgcat ttttagaacg aagttcacct gcagagattt gtttcaatcc
     4141 acctgggtgg tttgagtgag tgtagtagat tttatcagtt gcttttttac cagtcaattt
     4201 aactttttca gcattgataa caatcacgaa gtcacctgta tcagtgtgtg gtgtaaatgt
     4261 tggtttgttt tttccgcgaa gtacgctagc aactactgca gaaagacgtc caagtggtac
     4321 atcagttgcg tcaactacgt accatttacg ttcaacttgg cctggtttag ccataaatgt
     4381 tgttttgttc atgatttctc ctatatatag ttcgattttt gtttacggtg atgggtgttc
     4441 cttcccatcg aaaagtattt ggaaggttcc ggggcctttc aaatggggta aacaataccg
     4501 cctactatca taccaaattt cacccctaaa agtcaataga tataaaaaat atttttcggt
     4561 aacttctcaa aataactgaa agttatataa tcaagttaat ttgggaattt acctattaac
     4621 ttcggtagat ttttgggaat tttttcccta tttctccctg taactaaaat ccttttcaaa
     4681 aaatcacctt ttcttgattt ttaatcctat ttgctgtatg ataagggaaa agaaagggga
     4741 cagagatatg gcttttacca atacccacat gcggtctgct agttttggca ttgttaccag
     4801 cttgcccgat gacatcattg actctttttg gtatatcatc gatcatttct taaaaaatgt
     4861 ctttgaattg gaagaagaac tcgagtttca attgcttaat aaccaaggaa agattacctt
     4921 ccacttttca agtcaacacc tccctacagc cattgatttt gactttaacc atcctttcga
     4981 ccctcgttat cccccaagag tactggtttt agacatggac ggtagagaaa ctatcctcct
     5041 cccagaagaa aatgacctat tttaaaaact ctagccttca gttgcaagta actgaaaact
     5101 agagtttttc tattttttca aagcatcata caagttgcgg atcggttgtt ttaatatcgg
     5161 atggataaaa tgaggcgcaa tttcctgtaa ggactcaagg acaaaaaggc gttccgctat
     5221 gtaaggatga ggcaatatga ggtcgtctgt ataaaggatc tggtcctcca caaagagcaa
     5281 gtccaaatca atcaaacgag gtccccaatg cacttctctc acccgtccca gctctgactc
     5341 aatggctaac aaggtttcta acaagtcttg tgctggtagc caggtttcca cctcaaccac
     5401 ttgattggca aagctatcct gctccactcc accccaaggc tccgtctcta agacactgga
     5461 ctctttgaga atatggatgc cacgagctcg cagtttgtca atggcttgct tcaagtttac
     5521 ttgtttatct cccatattgc ttcctagggc gataaaggct cgttgcttgc ggcgatgaat
     5581 ggttaccgag caagtatcta gtgacaaatg caccggtgcc caaggttttt tcagttccaa
     5641 cttcatttct tggacaagag gataagactc aaaggtacgt tccaccagtt tataggctac
     5701 cgtttcaatc aaatcttcac tcgtttcctg aaaccaagtc gtccactgct gacacaattc
     5761 tccgtaatgg acagaggctg ttaaatccaa gtctgtagct gccttggtca tatcatagga
     5821 taggatggct gaaacgacaa atttctgccc caattctttc tcactaggaa aaagaccatg
     5881 ataggcaaac atttccaaat ccttaatctg cagttgatcc ataatgattc ctttctagaa
     5941 aaatccgctt gaagcggatt ctttttatag ccccattaaa cgataagctt ggtcacggag
     6001 atccttatct gtttcaaata gaccacgagc tactgtcgtc aaggttgcag tgcctggttt
     6061 tctaacacca cgcatactca tacacatatg ttccgcctca atgacaacaa aggctccttt
     6121 agcacctaga tagtccatca aggcatcggc cacttcgata ttcaaacgtt cttgaatttg
     6181 tggttttttc gaataaactt caaccgtacg ggctagctta gacaagcctg ccacacgacc
     6241 atctggaatg taggcaatgt gcgctctacc ataaaatggc aagaagtggt gttcacacat
     6301 ggtatggaaa aagatatcct tttctaccac catattatcg tcaataattt caaaggattt
     6361 tgacaaatgt tcctctgctg tttgaccaag acctgaaaaa atctcttgat acatacgggc
     6421 tacacgagca ggtgtttcct gcaagccctc gcgattaacg ttctctccta cagcctcgat
     6481 aatcattttt acagctgctt caatcttttg tgtatccatt ctcgttcttc ctctccatca
     6541 gataggccct cacttggctc aagaaataca aggaacctgt gacaatccta actgtttgtt
     6601 tctcttcttt tttatctgtc aaattctgat ctagaaaatc atgccaatct tggtagctga
     6661 gatttctaga cttagctgcc tctttcagca cgctttcatc cgtcgcccga ctatccgcaa
     6721 aatgtgttag agtaagctcg gtatctggca tggctcccag caagtccaac atatcctcca
     6781 aggctttggt tttgatacaa gtgaagagga tttccttatg atgatccgca aaacgttctt
     6841 gcaaggttac caacaaggcc ttgatagcat ggggattatg ggctccatcc aaaatcatca
     6901 agggatctct tgacacgatt tccaaacgcc ctggccaact tgtttcttcc aaggcttgac
     6961 caagaaagtc attgcttgct agctctcgac catcttcttg acaaaaagta tcaagtaaag
     7021 ctatggccat cccagcattc tctatttggt acaaaccaag caggctagtc tggaagcgac
     7081 cttgtctgac agcacttgta tagtcaaaga cttcccctgt caccacactt tcttgatgac
     7141 gaacctgata atctgtcccg taggcaagtc tcggcgcatc tttcccttcc gcaatgcggt
     7201 caatcacagt caaggcttct ggagcaatac gccctgttac caagggcatc ccttgtttga
     7261 taatacctgc cttctgctct gctatgacct ccaaggtgtc accaagtagg gccacatgat
     7321 ccaagccaat agttgtaatt cctgtcaaaa tgggctgaca gacattggta ctatccaaaa
     7381 gtccacccat gccaacttcc atgatggcca catctacttg ctctgaggca aagtagtcat
     7441 aggccagggc tgtgataatc tcaaactcag ttgtctcctg aaaattggaa gccactcccc
     7501 cctccagcaa agactgatag tctaccatga gggcttctag tctagcctcc gggatagatt
     7561 ccccattgat gctaatctgg tctgtataat gaatgagata gggcgagctg aaaacaccaa
     7621 ctctcagccc tagtttttct agcatatttt tcaaaaaagc aatggtcgaa cccttgccat
     7681 tggttcctcc gatatggatg actttgagtt tgagatgggg atttccgcgc aaagctaaca
     7741 gttccaccat tcgttccaag ccaaaatgcg gttgatccgt ccggtagtta gcaatccact
     7801 gattgttttc aatttctttc atcttattta tattgtttta aatctaaatt ttccgcttca
     7861 tcagccaatc gaatggctga tgcaatttca actgccatct tgtgactggc tacgtcatgc
     7921 acgcgcacca cttctacacc ctgtcttgca gcgatactgg ttacatgagc cgaagccgta
     7981 tctcgattgc ggaaaccaag ttctgtctca ggattgactt caaaaccatt ttcttcaaga
     8041 atattgatga caaaccgctt acgcgacact ccaagaaaga ttggatagcc cttctgatgt
     8101 agtttatcca aatcccgtaa aagaagcaaa ttttctttct tggtcagacc aaagccaatt
     8161 cctagatcca acaggatatt ttcttgtgca attccagctt gatttgctct cgctagtgca
     8221 cgttcaaaga aagtctccat caagtcttcg attggcaatt tttcaaagtt agctaactct
     8281 tcctctgtaa aagcttgtcc aaaaccaaaa tgaggaaaga tgagcgagct aggatgctga
     8341 ggtcgagcaa taactggatt aaacatgatg accactttcg caccagcctt agcaaccacc
     8401 tccgccattt tctcatcacc cataagacca gtgatatcat taactagatt ggcaccagca
     8461 gccaaagcag cttctgctac ctgactcttc caagtatcaa tagagatgag gacatcactt
     8521 tccttgcgaa tcgctttaat cactggaaca acacgctgga tttcctcttc tatctcaaca
     8581 tagctatagc tacttcccgg ccgagtcgat tctccgccga tatctagcat actagcccct
     8641 tctgctatca atttacgagc ctgctggagt gcctgctcaa gagcaaaaaa ttgaccacca
     8701 tccgaaaagg aatctggggt tacattgata attccgcaaa tagctgtctt tgcatgattt
     8761 actttagttg acatatcggt cactccctca aggcttttca ccatattatt tctctatttt
     8821 accataaaaa gaaaaagatg gacactattg cattcatctt ttttcccaat agaaacaagt
     8881 aagcaattgt caaaaatctt aaacagaaat ccctaatgtc cgactcatta tcaccacaag
     8941 tgccaataaa cagaaggcta ccccattaac aatcatgtga agcaagatag acatttccaa
     9001 acgttgagtc ttgtaagctg tccaagatag aacgattgac atacctccat aaatcaataa
     9061 agaaggtaaa ttacttggtt gatgcaataa agcaaagaca atcgtaccaa ccacaaaccc
     9121 caagttctcc ttgcctcgaa aaatcttttt aggaacaatc ccacggcaca agatttcctc
     9181 acaaatcgga gcaagcaagg ctagcaagaa gaagctagaa atcagagaac tattctgaac
     9241 catatcgtta atctgagact ggttagctgt tgtcgtctca tttgacagtt gcaacaagat
     9301 agaaccaagt atatttgacc cgacaataac taaataactc aagcccaaac gtgccaaatc
     9361 tttagctcta aaaaaagaaa aattaaaact agctaacttg gttttacgag ctcccataat
     9421 aaatagagcc agaaccacaa ttgaaaggcc agcaactatc agccctgact gtagcagggc
     9481 tacttctttt aaagtcaaaa tagaggtaac cactagggga acctgatata aaaggacggc
     9541 aagtaaaaag accaaaatcc agcctgcacg attcaacaat tctttccaca tatttttctc
     9601 ttttatcacc tatctccttt gtattaaaaa aggggggaaa tccccctggg tcattctatt
     9661 ataaggccat gctgatgtag ttaaggataa acaaggcatc caaaatccaa atcatggcat
     9721 gaacatcttt aacttgacct ttgacaagct tagtcaaagt gtaagtcaag aaaccaactg
     9781 caatcccttg agtgatagag tagctgaatc ccataaagat agatgtgaag aaggcaggaa
     9841 ctgcttcaga catatcatcc caatggatat ttttcaagct accaagcatc ataatcccaa
     9901 cgataatcaa gattggagct gtagccgctg ttggtacgat cgctagaagc gggctaaaga
     9961 agcttgaaat cgcaaaacag atagctacaa ccaaggctgt caaaccagta cgtccacctg
    10021 caccgatacc agcagcagac tcaacataag tcgttacgtt tgaagtacct gcaatggcac
    10081 cgactgtcgt tccaatcaaa tcagagtaaa gagccttatc caatttggct gattggtgat
    10141 tttcaccatt tgtcgctaca ataccaactt tttcacctgt accgatcaag gtaccaattg
    10201 tgtcaaaaat atctgtcaat gagaaggcaa gaatggccat cagagtttca ggcaagcgag
    10261 ctgtatctga aaccaaagct cccaaacctt ctgaaccaag agctgcacca aagattgtct
    10321 tcaaatcttc aaaagctgca ccaacatggt tattagcaaa atcgatacta gacaaatcaa
    10381 ccaaaccaac tgcaatagca agaacagttg ttgtcaagat agagagaata attccccctt
    10441 taatcccttt gatgacaaag aagatagtaa tggcaagtcc tgcaagagcc actaaaacag
    10501 ctggattatt aaagctgacc aatcctggaa ctgctgaaga gtttgctgca atcgttgctt
    10561 gagctttgtc agccccttct cctacaacag tatagttgcc tggatcaatc gtgaatttca
    10621 aaagtccagc attcttaatc cctacatagg caaggaagac accgatacca gctgaaatag
    10681 ctgagcgaag agcattggga atcgattcaa tgatcatttt acgaacattt gtcaaggtaa
    10741 taatcaatga aataatccca cagatgaaga ccatagctag ggcttcttgc caagaataac
    10801 caagcccgaa tacaactgta aaggtaaaga aggcattgag tcccatacct ggcgcttggg
    10861 cataaggtaa gttagcataa aaagccatca tcaaggtacc cgctactgca ccaataatcg
    10921 tcgctaggaa gacgccctga gcaggcattc ctgtttgtga aagtatttgt gggtttacaa
    10981 agagaatata gctcattgca aagaaagttg ttaaaccagc gagaacctct gtacgaacgt
    11041 ctgtaccgtt ctcttttagt ttaaataatt tgtccatcat caatctcctt ttaattttta
    11101 cgaacaataa tagaattata tcatttatca ttcacttttt caatgtcttt gtttgatttg
    11161 tttaagaaat taatccaatt tcattttttg tttggaatct gcttttctgc ctgctttctg
    11221 ttataataga agacatctta tctgaaaaca cactagaaag gtccatatga cgaaaaaaat
    11281 tattgcagtt gacctggatg gaaccctgct caactcagac agtcaaattt ctgactttac
    11341 caaaaaaacc atcaaaaaag ttgctgaaaa aggccatcag gttattatta cgacaggtcg
    11401 cccttaccgt atgtcaaaag atttttaccg tgaactgggc ttagacactc ctatgattaa
    11461 cttcaacgga tcccttactc atttaccaga ccaagtttgg gattttgaaa agtgtttgac
    11521 tgtagacaaa aaatatctgc tagatatggt tcaacgttca gaggacattc aagccgattt
    11581 tatcgctgga gaatatcgta aaaaattcta cattacaaat cccaatgaag aaattgccaa
    11641 tcccaaacta tttggtgtag aagctttcca gcctgaagat caattccagc ctgaattggt
    11701 gaccaaggac cctaactgta tcctcttgca gaccagagcc agtgacaaat atgccttggc
    11761 aaaagacatg aacgccttct accagcatca actttctatc aatacctggg gaggtccgct
    11821 caatatcctt gaatgtaccc caaaaggtgt caacaaggcc tttgctttgg actacttgct
    11881 caagataatg aatcgtgaca aaaaagattt gattgccttt ggagatgaac acaatgatac
    11941 cgaaatgctc gcttttgctg ggaagggtta tgccatgaaa aatgccaatc cagagctact
    12001 cccttatgca gatgagcaaa tttcccttac caacgaccaa gatggggttg ccaaaaccct
    12061 acaagactta ttcttataac ctatactgat actcaatgag aatcaaagag caaactagga
    12121 agctagccgt aggttgctca aagcactgct ttgaggttgt agatgaagct gacgtggttt
    12181 gaagagattt tcgaagagta tgaccagctt gcaagctggt ctttgtgctc ttttcacagt
    12241 ctcatcaacc agttaatcga ttgttctact ttttgtctcc aaaaccttgg aaaaggcttc
    12301 cttttgtgat atacttcaca tataaataca agagagctcg tcacactcga ctctgttgac
    12361 aaaaaatcaa tccagtcccg ttgtccctgt tctcggtcaa tatcaaggag gatagctatg
    12421 aaagctgttg ttgtaaatcc agaaagcact ggtgttgcta ttgaagaaaa agtactccgt
    12481 ccacttgaaa ctggggaagc acttgtagaa gttgaatact gtggcgtttg ccacaccgac
    12541 ctccacgttg ctcatggtga ctttggtcaa gtcccaggac gtgttcttgg gcacgaaggt
    12601 atcggtatcg ttaaagagat tgctccagat gtgaaaagcc ttaaagtcgg tgaccgcgtc
    12661 agcgttgctt ggttctttga aggatgtggc acttgcgaat actgtacaac tggtcgcgaa
    12721 accctttgcc gtacagtgaa aaatgctggc tactcagtag acggtggtat ggctgaacaa
    12781 tgtatcgcaa ctgctgacta tgctgtcaaa gttcctgacg gacttgatcc agcccaagct
    12841 tcttctatca catgtgctgg agtaacaacc tataaagcta tcaaagaagc aaaagttgaa
    12901 ccaggccaat gggttgttct ttacggtgct ggtggacttg gtaacctcgc tgttcaatac
    12961 gctaaaaaag tattcaatgc tcatgttatc gcagtcgata tcaacaatga caaacttacc
    13021 cttgcaaaag aagtaggcgc tgacattgtg attaacggcc tcgaagttga agatgtagct
    13081 ggactcatta aagaaaaaac tgatggagga gctcattcag ctgtcgtaac tgctgtgtct
    13141 aaagttgcct tcaaccaggc tgttgactcc attcgtgctg gtggtcgcgt cgtcgctgtt
    13201 ggtcttcctt ctgaaatgat ggaactcagc atcgttaaaa cagtcctcga tggaatccaa
    13261 gtcatcggtt ctcttgtcgg aactcgtaaa gacttagaag aagccttcca atttggtgca
    13321 gaaggtctgg tagtcccagt tgttcaaaaa cgtccagtag aagatgctgt tgccattttc
    13381 gacgaaatgg aaaaaggcca aatccaagga cgtatggtac tcgacttcac ccactaattt
    13441 aatagaaacc tattt
//
LOCUS       DAVLMQ010000045        13352 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000045 DAVLMQ010000000
VERSION     DAVLMQ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13352
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.045"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            44..6067
                     /locus_tag="VXF95_001665"
     CDS             44..6067
                     /locus_tag="VXF95_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1082182.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVAGASLAALGILIFAVSKKKVKNKTVLHLVLVAGIGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYREETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGKLGKKVEIVRIFSVNKEEVSREIVSTSTTAPSPRIVEKGTK
                     KTQVIKEQPETGVEHKDVQSGAIVEPAIQPELPEAVVSDKGEPEVQPTLPEAVVTDKG
                     EPAVQPELPEAVVSDKGEPEQVAPLPEYKGNIEQVKPETPVEKTKEQGPEKTEEVPVK
                     PTEETPVNPNEGTTEGTSIQGAENPVQPAEESTTNSEKVSPDTSSENTGEVSNKPSDS
                     TTSVGESNKPEHNDSKNENSEKTVEEVPVNPNEGTVEGTSNQETEKPVQPAEETQTNS
                     GKIANENTGEVSNKPSDSKPPVEESNQPEKNGTATKPENSGNTTSENGQTEPEPSNGN
                     STEDVSTKSNTSNSNGNEEIKQENELDPDKKVEDPEKTLELRNVSDLELYSLSNGTYK
                     QHISLEQVPSNPNSYFVKVKSSSFKDVYLPVASISEERKNDKILYKITAKVEKLQQEI
                     ESRYKDNFTFYLAKKGTEETTNFTSFSNLVKAINQNLSGTYHLGASLNANEVELSTDD
                     KSYIKGTFTGQLIGEKDGKHYAIYNLKKPLFENLSGATVEKLSLKNVAISGKNDIGSL
                     ANEATNGTKIKQVHVDGVLAGERGVGGLLAKADQSSIAESSFKGRIVNTYETTDSYNI
                     GGLVGHLTGKNASIAKSKATVTISSNTNRSDQTVGGLAGLVDRDAQIQDSYAEGDINN
                     VKHFGRVAGVAGNLWDRTSGDVRHAGSLTNVLSDVNVTNGNAITGYHYTGMKVANTFS
                     SKANRVFNVTLEKNEVVSKESFEERGTMLDASQIASKKAEINLITPPIVEPLSTSGKK
                     DSDFSKIAHYQANRALVYKNIEKLLPFYNKATIVKYGNLVKENSILYQKELLSAVMMK
                     DDQVITDIISNKQTANKLLLHYKDHSSEKFDLRYQADFANLAEYSIGDSGLLYTPNQF
                     LYHQDSIINQVLPELNRVNYQSDAVRNTLGISPEVKLTELYLEEQFTKTKEHLAENLK
                     KLLSSDAGLVTDNEVMTGYIIDKIKRNKEALLLGMSYLERWYNFSYGQVNVKDLVMYH
                     PDFFGKGNTSPLDTLIELGKSGFNNLLAKNNVDTYAISLASHHGTTDLFSTLENYRKV
                     FLPDKTNNDWFKSQTKAYIVEEKSNIEEVKTKQGLVGTKYSIGVYDRITSATWKYRNM
                     VLPLLTLPERSVFVISTISSLGFGAYDRYRNKEHQANGDLNSFVEKSAHETAERQRDH
                     YDYWYRILDEKGREKLYRNILLYDAYKFGTNHTEGKATEVADFDSPNPAMKHFFGPVG
                     NKVGHNGHGAYATGDAVYYMGYRMLDKDGAITYTHEMTHNSDQDIYLGGYGRRSGLGP
                     EFFAKGLLQAPDQPSDATITINSILKHSKSDSKEGERLQVLDPTTRFKDATDLQKYVH
                     NMFDVVYMLEYLEGKSIVKKLNVYQKIEALRKIENQYLTDPADGNDVYATNVVKNLTE
                     DEAKKLTSFDSLIDNNILSAREYKAGTYERNGYFTIKLFAPIFSALSGEKGTPGDLMG
                     RRIAFELLAAKGFKDGMVPYISNQYEEDAKQQGQTINLYGKERGLVTDELVLKKVFDG
                     KYKTWAEFKTAMYQERVDQFGNLKQVTFKDPTKPWPRYGTKTINNVDELQKLMDEAVL
                     QDAKERNYYYWNNYNPETDSAVHKLKRAIFKAYLDQTNDFRRSIFENKK"
     gene            6111..11435
                     /locus_tag="VXF95_001666"
     CDS             6111..11435
                     /locus_tag="VXF95_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HEV1082183.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGTSTYHYLDYS
                     TLTQTERVQLKQGRPDESKESYALVYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DKKRKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVDYLELDDR
                     TVSPVEQPKVVTDKGEPEVQPALPEAVVTGKGKTEVQPTLPEAVVTEKGEPEVQPVLP
                     EAVVAEKGEPEVQPALPEAVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPV
                     GTTGVDENRNLIEPPVNDIPEYTEPISTVSEVASEREELPSLHTDIRTETIPKTTIEE
                     SDPSKFIGDNSVKQVGEDGERQIVTSYEELHGKKISESVETVTILKEMKPEIIVKGTK
                     ERPKEKTAPVLTLTKVTEDAMNRSANLNYELDNKDNAEISSIVAEIKDGDTVVKRVDL
                     SKEKLTDAVQNLDLFKDYKIATTMIYDRGQGSETSKLDERPLRLELKKVEIKNIASTN
                     LVKVNDDGTETPSDFMNEKPSEEDVKKMYLKITSRDNKVTRLTVDSIEEVTEEGQKLY
                     KITAEAQDLIQHTDPTKVRNKYVYYIEKPHPKEDNVYYNFKDLVDAMNTDKNGTFKLG
                     ADLNATGVPTPKKWYVDGDFRGTLKSVEGKHYTIHNTERPLFQNIIGGTVTKVNLGNV
                     NINMPWADRIAPIADTIKGGAKIEDVKVTGNVLGRNWVSGFIDKIDNQGTLRNVAFIG
                     NVTSVGDGGQFLTGIVGENWKGLVERAYVDANLIGKKAKAAGIAYWTQNSGDNHKVGV
                     EGAVKKGIVKGTIQVESPVEVGGAVGRLSHHGYIGEVVSMMKVKKGEIFYGSSDMNDD
                     PYWVANNVRGNYVVNGVSEGTISYARAKEHHRIKPISQSEADTKIMMLGITAQDFAIN
                     EPVVNRLNRLTRKEDEYKSTQDYKVDRDLAYRNIEKLQPFYNKEWIVNQGNKLAEDSN
                     LAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGTKEEMDVTKNADSKVKQVREYTIA
                     GQNVVYTPNMVEKDRNQLIQDIKDKLASVQLISPEVRALMDARKKPEENTDERKNGYI
                     KDLYLEESFAETKANLDKLVKSLVENADHQLNSDEAAMKALVKKVDENKAKIMMALTY
                     LNRYYDIKYGDMTIKNLMMFKPDFYGKSVDLLDFLIRIGSSERNIKGDRTLDAYRDMI
                     GGTIGKSELHGFLDYNMRLFTNDTDLNDWFIHAAKNVYVSEPQTTNPDFVNKRHRAFD
                     GLNNGVHNRMILPLLTLKNAHMFLISTYNTMAYSSFEKYGKYTEEARNEFKKEIDKVA
                     HAQQTYLDFWSRLALPSVRDQLLKSENRVPTPVWDNQNYSGIKGINRMGYDEKKVPIA
                     PIRELYGPTWKFHNTNWNMGAMASIFPNPNNNDQVYFMGTNMISPFGISAFTHETTHV
                     NDRMLYFGGHRHRQGTDVEAYAQGMLQTPSSIGHQGEYGALGLNMAYHRENDGDQWYN
                     YDPDKLQTREDIDRYMKNYNEALMMLDHVEADAVLPQLNGDNSKWFKKIDREIRRNLG
                     DGLNNLVAPHQWDNVRDLNQEESSKKLSSINDLIDNNFMTKHGNPGNGRYRPEDFRPN
                     SAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGYYGYDKGFTSYVSSKYQGEADK
                     QNQGRLGDDFIIKKVSNNQFSNLEDWKKYWYHDVKSRAEKGFTEITIDGQTIHNYNEL
                     KDLFDKAVTEDLKKAGNYSNTENLKSKVFKALLKNTDGFFNPLFKKDI"
     gene            11602..12948
                     /locus_tag="VXF95_001667"
     CDS             11602..12948
                     /locus_tag="VXF95_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HEV1082184.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCRYSDSDILVQFLFQLLTGYGTDYACKELSADAYFPKLLEGGQL
                     ASQPTLSRFLSRTDEETVHSLRCLNLELVEFFLQFHQLNQLIVDIDSTHFTTYGKQEG
                     VAYNAHYRAHGYHPLYAFEGKTGYCFNAQLRPGNRYCSEEADSFITPVLERFNQLLFR
                     MDSGFATPKLYDLIEKTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSET
                     LYQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIK
                     EMKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFFKHLAGGDFQTLTIKRFRHLFLH
                     VVGKCVRTGRKQLLNLSSLYAYSELFSALYSRIRKVNLNLPVPYEPPRRKASLMMH"
BASE COUNT         4714 a         2254 c         2709 g         3675 t
ORIGIN      
        1 aaggtctttg taacatatat aaattttatt tcaaggagga ataatggaaa agtattttgg
       61 tgaaaaacaa gagcgttttt catttagaaa attatcagta ggacttgtat ctgcaacgat
      121 ttcaagttta ttttttatgt ctgtattagc tagttcatct gtggatgctc aagaaactgc
      181 gggagttcac tataaatatg tggcagattc agagctatca tcagaagaaa agaagcagct
      241 tgtctatgat attccgacat acgtggagaa tgatgatgaa acttattatc ttgtttataa
      301 gttaaattct caaaatcaac tggcggaatt accaaatact ggaagcaaga atgagaggca
      361 agccctagtt gctggtgcta gcttagctgc tctgggaatt ttaatttttg ctgtttccaa
      421 gaaaaaggtt aagaataaaa cggtattaca tttagtattg gttgcgggaa taggaaatgg
      481 tgtcttagtt tcagtccatg ctttagaaaa tcatcttttg ctaaattaca atacggacta
      541 tgaattgacc tctggagaaa aattacctct tcctaaagag atttcaggtt acacttatat
      601 tggatatatc aaagagggaa aaacgacttc tgattttgaa gtaagtaatc aagaaaaatc
      661 agcagccact cctacaaaac aacaaaaggt ggattataat gttacaccaa attttgtaga
      721 ccatccatca acagtacaag ctattcagga acaaacacct gtttcttcaa ctaagccgac
      781 agaagttcaa gtagttgaaa aacctttctc tactgaatta atcaatccaa gaaaagaaga
      841 gaaacaatct tcagattctc aagaacaatt agccgaacat aagaatctag aaacgaagaa
      901 agaggagaag atttctccaa aagaaaagac tggggtaaat acattaaatc cacaggatga
      961 agttttatca ggtcaattga acaaacctga actcttatat cgtgaggaaa ctatagagac
     1021 aaaaatagat tttcaagaag aaattcaaga aaatcctgat ttagctgaag gaactgtaag
     1081 agtaaaacaa gaaggtaaat taggtaagaa agttgaaatc gtcagaatat tctctgtaaa
     1141 caaggaagaa gtttcgcgag aaattgtttc aacttcaacg actgcgccta gtccaagaat
     1201 agtcgaaaaa ggtactaaaa aaactcaagt tataaaggaa caacctgaga ctggtgtaga
     1261 acataaggac gtacagtctg gagctattgt tgaacccgca attcagcctg agttgcccga
     1321 agctgtagta agtgacaaag gcgaaccaga agttcaacct acattacccg aagcagttgt
     1381 gaccgacaaa ggtgagcccg ctgtccaacc tgaattaccc gaagcagttg taagtgataa
     1441 aggtgaacca gagcaggtag caccattgcc agaatataag gggaatattg agcaagtaaa
     1501 acctgaaact ccggttgaga agaccaaaga acagggtcca gaaaaaacgg aagaagttcc
     1561 agtaaaacca acagaagaaa caccagtaaa tccaaatgaa ggtactacag aaggaacctc
     1621 aattcaagga gcagaaaatc cagttcaacc tgcagaagaa tcaacaacga attcagagaa
     1681 agtatcacca gatacatcta gcgaaaatac tggggaagta tccaataaac ctagtgattc
     1741 gacaacctca gttggagaat caaataaacc agaacataat gactctaaaa atgaaaattc
     1801 agaaaaaact gtagaagaag ttccggtaaa tccaaatgaa ggcacagtag aagggacctc
     1861 aaatcaagaa acagaaaaac cagttcaacc tgcagaagaa acacaaacaa actctgggaa
     1921 aatagctaac gaaaatactg gagaagtatc caataaacct agtgattcaa aaccaccagt
     1981 tgaagaatca aatcaaccag aaaaaaacgg aactgcaaca aaaccagaaa attcaggtaa
     2041 tacaacatca gagaatggac aaacagaacc agaaccatca aacggaaatt caactgagga
     2101 tgtttcaacc aaatcaaaca catccaattc aaatggaaac gaagaaatta aacaagaaaa
     2161 tgaactagac cccgataaaa aggtagaaga tccagagaaa acacttgaat taagaaatgt
     2221 ttccgaccta gagttataca gtttgtcaaa tggtacttat aaacaacaca tttcgttaga
     2281 gcaagttcca agcaatccaa atagctactt tgttaaagtg aaatcttctt cattcaaaga
     2341 tgtataccta ccagtagcat caatatcaga ggaaagaaaa aatgataaaa tcctttataa
     2401 aatcacagca aaagtagaga agcttcagca ggagatagaa agcagatata aagataattt
     2461 taccttctat ctagctaaga agggaacaga agaaacaaca aactttactt cctttagtaa
     2521 tctggtcaaa gctataaacc aaaatctctc tggaacctat catttaggag ctagcctgaa
     2581 tgctaacgaa gtggagctta gtactgatga taaatcctat atcaagggaa cctttactgg
     2641 tcagttgatt ggtgaaaaag atggtaagca ttatgctatt tacaacttga aaaagcctct
     2701 ttttgaaaac ttgagtggtg ctacagtaga aaaactgagt ctaaaaaatg ttgctatttc
     2761 agggaaaaat gatattggtt cactggcaaa tgaagctacg aatggcacaa agattaaaca
     2821 agttcatgtt gatggtgttc ttgctggaga acgtggtgtc ggtggtttgt tggctaaggc
     2881 agaccaatca agcatcgcag agagcagttt caagggaaga attgtcaata cctatgaaac
     2941 gactgattcc tacaatattg gcggtctggt cggtcattta acaggaaaaa atgcgtctat
     3001 tgctaaatcc aaagcgacag taaccatttc gtcaaacacc aataggtcag atcagactgt
     3061 cggtggtctt gcaggtctag tagaccgaga tgcacagatc caagatagct atgctgaagg
     3121 tgatatcaac aatgtcaagc actttggtag agtcgctgga gtggcaggca atttgtggga
     3181 tcgaacttct ggtgatgtta ggcatgctgg aagtttgacc aatgttctca gcgatgttaa
     3241 tgtaacaaac ggaaatgcca tcactggata ccactataca ggaatgaagg tagctaatac
     3301 atttagtagt aaggctaata gagttttcaa tgtcacttta gagaagaatg aggtcgtcag
     3361 caaagaatcc ttcgaggaaa gaggaacaat gctagatgct tctcaaattg caagcaaaaa
     3421 agcagaaatc aatcttatca ctccaccaat agtggaaccc ctctcaacaa gcggtaagaa
     3481 agacagtgat ttttctaaga tagcccatta tcaagccaac cgtgctttgg tttataagaa
     3541 cattgaaaaa ttgttacctt tctataacaa ggcgaccatc gtgaaatacg gaaacctggt
     3601 taaggagaac agtatcttat atcaaaaaga actcttgtct gcagttatga tgaaggatga
     3661 ccaagtaatc acagatatta tttccaacaa acagactgca aacaaactct tgcttcacta
     3721 caaggaccat tcatctgaaa agtttgatct caggtaccag gctgattttg ccaatttggc
     3781 agaatatagc attggagata gtgggcttct ctatacgcca aatcaattct tgtatcatca
     3841 agattctatt attaaccaag tgctgcctga attgaatcga gtaaattatc aatcagatgc
     3901 tgttagaaat acacttggaa tttcaccaga agtgaagcta acggagttat atcttgaaga
     3961 acaatttacc aaaacgaaag agcatctagc agagaacttg aaaaaacttt tatcatctga
     4021 tgcaggttta gtaacagaca atgaagttat gacaggatat ataatagata aaattaaacg
     4081 gaataaggaa gccttacttc ttggaatgag ttatttagaa cgttggtata actttagcta
     4141 tggtcaagtg aatgtcaaag acctagttat gtatcatccg gacttctttg gtaaaggaaa
     4201 tacttcacca ttagatactc tgattgagtt aggtaaatct ggctttaaca atcttcttgc
     4261 taaaaacaat gtcgatactt atgctatcag ccttgccagc catcatggaa cgacagattt
     4321 gtttagcacg ttggaaaatt accgaaaagt ctttctacca gataaaacca ataatgactg
     4381 gtttaaatca cagactaagg cttacattgt cgaagaaaaa tccaatatcg aagaggtgaa
     4441 aacgaagcaa ggactagttg gcactaagta ttctattggt gtctatgacc gtatcactag
     4501 tgccacatgg aaataccgta atatggtact acctctactt accttgccag aaagatccgt
     4561 atttgtcatt tcaaccatat ctagtctagg ttttggtgct tatgatcgct atcgtaataa
     4621 agaacatcaa gcaaatggtg atcttaatag ctttgttgaa aagagtgctc acgaaacagc
     4681 agagcgtcaa cgagatcact atgattattg gtatcgtatt ctagatgaaa aagggcgtga
     4741 aaagctttat cgaaatatct tgctttatga tgcctataaa tttggaacta atcatactga
     4801 aggaaaggct acagaagtag cagattttga tagtccaaat cctgcaatga aacatttctt
     4861 tggacctgtt ggaaataagg ttggacataa tggacatggt gcttatgcta caggggatgc
     4921 agtatattat atggggtatc gcatgctaga taaggatgga gctattacgt atactcatga
     4981 gatgacgcat aattcagatc aagatattta tcttggtggt tatggaagaa gaagtggact
     5041 tggacctgag ttctttgcta aaggcttact acaagcacca gaccaaccaa gtgatgcaac
     5101 gattactatc aattctatat tgaaacattc aaaatctgat agtaaagaag gagaacgatt
     5161 acaagtactt gatccaacta cgagatttaa agacgcaaca gatcttcaaa aatacgtcca
     5221 caatatgttt gatgttgttt atatgttgga atatctcgaa ggtaaatcta ttgttaagaa
     5281 attaaatgta tatcagaaaa tagaagctct cagaaaaatc gagaaccaat atctaacaga
     5341 tcctgctgat ggaaatgatg tttatgctac taatgttgtg aaaaatttga ctgaagatga
     5401 agctaaaaaa ttgacgagct ttgatagttt gattgacaat aacattcttt cggctcgtga
     5461 gtataaggct ggcacttatg agagaaatgg ctactttact ataaaactct ttgcaccaat
     5521 cttttcagca ttgagcggtg agaaaggaac tccaggtgac cttatgggac gaaggatagc
     5581 ttttgaactt ctagctgcta aaggatttaa agatggtatg gtaccatata tttccaacca
     5641 atacgaagaa gatgctaaac aacaagggca aactatcaat ctttatggta aagaacgggg
     5701 cttggtgacc gatgagcttg ttttgaaaaa ggtatttgat ggtaagtata aaacttgggc
     5761 agaatttaag acagctatgt accaagaacg ggtggatcag tttggaaact tgaagcaggt
     5821 gacctttaaa gatccgacaa aaccatggcc aagatatggc acaaagacta tcaataatgt
     5881 ggatgaattg cagaaactaa tggatgaagc tgttttgcag gatgcaaaag aacgtaatta
     5941 ttattattgg aataactata atccagaaac ggacagtgcc gtccataagt tgaagagagc
     6001 aatctttaaa gcctatcttg accaaacaaa tgattttaga agatcaattt ttgagaataa
     6061 aaaatagtgt ttactattag gaaataaaaa gtgaatgtgg aggattagaa ttgtcattat
     6121 taaaaaaaga taaattttcc attcggaaaa taaagggtat tgttggttcg gtattcttgg
     6181 ggagtctttt atttgcaccg tcagttgttg gtacatcgac ttatcattac ttagattata
     6241 gtactttgac acaaactgaa cgtgttcaac tcaaacaagg tagacctgat gaatcaaaag
     6301 agtcatatgc tttggtttat gaaaaagacg cattaccaaa cacaggaagt tctcaatcta
     6361 ttatgactgc attgggtttg ttagctatcg ggagtcttat tgtgattatc acaaaagata
     6421 aaaagaggaa aaaaatcgct acatttttga ttgtaggggc gacaggttta gttacactat
     6481 caactgcttc agcacttaat ttgaatgcta acatccatga gtctggacgt gatggtgtgt
     6541 tgcaaatttc tggttacaga tatgttgatt acttggagct tgatgataga actgtttctc
     6601 cagttgagca acccaaagtt gtgaccgaca aaggcgaacc agaagttcag ccagcgttac
     6661 cagaagctgt tgtaactgga aaagggaaaa ctgaagtaca accgacatta ccagaagctg
     6721 ttgtgactga aaaaggggaa ccggaagtac aaccagtgtt accagaagct gttgtggctg
     6781 aaaaagggga accagaagta caaccagcct tacccgaagc agttgtaact gaaaaaggcg
     6841 aaccagaagt tcatgagaag cctgactata cgcaaccaat aggtgcaaac cttgttgagc
     6901 ctgaagttca tgagaaacta gcatacactg aacctgtagg tacaacagga gtagatgaaa
     6961 atagaaactt gattgagcca cctgttaacg atattccaga gtatactgaa ccaatatcta
     7021 cagtttcaga agttgcatca gaaagagaag agttgccttc tttacatacc gatattcgta
     7081 cagagactat tcctaaaacc actatagaag aatctgatcc tagcaaattt ataggcgata
     7141 attctgttaa acaagttggt gaggatggcg aacgtcaaat tgttactagc tatgaagagt
     7201 tacatggcaa aaaaatcagc gagtcagttg aaacagtaac aattttgaaa gaaatgaagc
     7261 ctgaaattat tgtaaaaggt acaaaagaaa gaccaaaaga aaaaacggct cctgttttaa
     7321 ccttgaccaa agtaacagaa gatgctatga atcgttctgc caacttaaat tatgagcttg
     7381 ataataaaga taatgctgaa atatcaagta ttgtagctga aattaaagat ggtgatacag
     7441 tagttaaaag ggttgattta tctaaagaaa aattaactga cgctgtacaa aatttggatt
     7501 tgtttaaaga ttataagatt gcaacaacaa tgatttatga tcgtggtcaa ggttctgaaa
     7561 cgtctaaact ggatgaaaga cctctgcgtt tggagttgaa aaaggtcgaa attaaaaata
     7621 tcgcatctac taatttagtg aaggtaaatg atgatggtac tgaaacacct agtgatttta
     7681 tgaatgaaaa accttcagaa gaagatgtta aaaaaatgta cttaaaaatc actagtcgcg
     7741 ataataaggt aactcgttta actgtagact ctattgaaga agtgactgaa gaaggtcaaa
     7801 aactttacaa aataactgct gaagcacaag atttgattca acacacagac ccaacgaagg
     7861 ttcgtaataa gtatgtttat tatatagaaa aaccccatcc taaagaagat aatgtctact
     7921 ataactttaa agatttagta gatgctatga atactgataa aaatggtaca tttaaacttg
     7981 gtgcagattt gaatgccact ggtgttccaa cacctaagaa atggtatgtt gacggcgact
     8041 ttagaggtac attgaagagt gtagagggga aacattatac tatccacaac acggagcgtc
     8101 cgttattcca gaatattatt ggtggtacag taaccaaagt aaatctggga aatgtaaata
     8161 tcaatatgcc atgggcagac cgcatcgcac cgattgctga cactattaaa ggtggcgcta
     8221 aaattgaaga tgtcaaagtg actggtaacg tattaggtag aaactgggta tctggattta
     8281 ttgataagat tgacaaccaa ggtacactca gaaatgtagc ctttatcgga aatgtgacat
     8341 ctgtaggtga tggtggtcaa ttcttgaccg gtatcgttgg tgagaactgg aaaggactag
     8401 tcgaacgtgc gtatgttgac gcaaatctta ttggcaagaa agccaaggct gctggtattg
     8461 cttattggac acaaaacagt ggtgacaatc ataaagttgg tgtcgaaggt gcagtcaaga
     8521 aaggaattgt gaagggtacc attcaggtag aaagtcctgt tgaagtcggc ggtgctgttg
     8581 gacgtttgag tcatcatggt tatatcgggg aagtcgtatc tatgatgaaa gttaagaagg
     8641 gtgaaatttt ttatggttct agtgatatga atgatgaccc atattgggtg gcgaataatg
     8701 tacgaggaaa ttatgtagtt aatggtgtga gtgaaggtac gatatcttat gctcgtgcta
     8761 aagaacacca tcgtatcaaa ccaatttcac agtcagaagc agatactaaa attatgatgt
     8821 taggtattac agcacaagat tttgctatca acgaacctgt ggtcaatcgc ttaaaccgtt
     8881 taaccagaaa agaagatgaa tataagtcaa cccaagacta taaagtagat cgagatctgg
     8941 cttatcgtaa tattgagaaa cttcaaccat tttataacaa agaatggatt gtcaaccaag
     9001 gtaacaaact tgcagaagat tcaaacttag ctaagaaaga agtcctttct gttacgggta
     9061 tgaaggatgg acagtttgta actgacttat cagatattga taagattatg gttcactatg
     9121 ctgatggtac taaagaagaa atggacgtca ctaagaatgc tgattctaaa gtgaaacaag
     9181 ttcgtgaata taccatcgct ggacaaaacg ttgtttatac accaaatatg gttgagaaag
     9241 accgtaacca attgattcaa gatatcaaag ataagttggc gtcagttcaa ttgatttctc
     9301 ctgaagtacg tgctttgatg gatgcacgta agaaaccaga agaaaatacc gatgaacgta
     9361 agaatggtta tattaaagac ctttacttag aagaaagctt tgctgaaacg aaagctaatc
     9421 ttgataaatt ggttaaatcc ttagttgaaa atgcagatca tcaattaaat agtgacgaag
     9481 cggctatgaa agcacttgtt aagaaggtgg atgaaaataa agctaaaatc atgatggctc
     9541 tgacttatct caatcgttac tatgatatca agtatgggga tatgactatc aagaacttga
     9601 tgatgtttaa acctgatttc tatggtaaat cagttgacct tcttgatttc ttgattcgaa
     9661 ttggatcaag tgagagaaat atcaaaggtg acagaacttt ggatgcttat cgtgatatga
     9721 ttggtggaac tattggtaag tctgaattac atggattctt agattacaat atgcgtctct
     9781 tcactaacga tactgattta aatgattggt tcatccatgc agctaagaat gtatatgtat
     9841 cagaacctca aacaacgaac ccagattttg ttaataaacg acatcgtgca tttgatggtt
     9901 tgaacaacgg tgttcataat cgtatgattc tacctctatt aactcttaag aatgcacata
     9961 tgttcttgat ttcaacttac aatacaatgg cttatagttc ttttgagaaa tatggtaagt
    10021 atacagaaga agctagaaat gaattcaaaa aagaaattga taaggttgca catgctcaac
    10081 aaacatactt agacttctgg tcacgtttag cattgccaag cgtacgtgac caattactca
    10141 agagtgagaa tagggtacca actcctgtgt gggataacca aaactatagt ggtattaaag
    10201 gaataaaccg tatgggttat gatgagaaga aagtaccaat tgcgccaatt cgtgagttat
    10261 atggtccaac ttggaaattc cataatacca actggaatat gggagctatg gcatctattt
    10321 tcccaaatcc taataacaat gaccaagttt atttcatggg aacaaatatg attagtccgt
    10381 ttggtatttc agcctttact catgaaacta cacacgttaa tgatagaatg ctttacttcg
    10441 gtggtcatag acaccgtcaa ggtacagacg tcgaagccta tgctcaaggt atgctacaaa
    10501 ctccgtcaag tattggtcac caaggtgaat atggtgcttt aggtttgaac atggcttatc
    10561 atcgtgaaaa tgatggtgac caatggtata actatgaccc tgataagctt caaactcgtg
    10621 aagatatcga tcgatatatg aaaaactata atgaagcact gatgatgcta gatcatgtag
    10681 aagcagacgc cgtacttcca caattgaatg gtgataatag caagtggttc aagaaaattg
    10741 atagagaaat acgcagaaat cttggggatg gtttgaataa cttagtagca ccgcaccaat
    10801 gggacaacgt tcgtgactta aatcaagaag agagttctaa gaaattatca agtattaacg
    10861 atttgattga taataatttc atgaccaaac acggaaatcc aggtaacgga cgttatagac
    10921 cagaggattt tagaccaaac tcagcttacg taaatgtcaa tatgatggca ggaatttacg
    10981 gtgggaatac gagtcaaggt gctcctggtt cattatcgtt caaacataat gccttccgta
    11041 tgtggggtta ttatggatat gacaaaggtt tcactagtta tgtatctagc aaatatcaag
    11101 gtgaagctga taaacaaaac cagggtagat taggtgatga tttcattatc aaaaaagttt
    11161 caaacaacca attctcaaat cttgaagatt ggaagaaata ttggtatcat gatgtgaaat
    11221 ccagagctga aaaaggattc acagagatta caattgatgg acaaaccatt cacaactata
    11281 atgaactgaa agacttattc gacaaagctg tcacagaaga cctcaagaaa gctggaaact
    11341 actcaaatac tgagaatttg aaatccaaag tcttcaaagc tcttcttaaa aacacagacg
    11401 gtttctttaa tccattgttc aaaaaagaca tttaaacccc aattatgcac ccctaatcta
    11461 aaaaccatcc agaatccttg ccttagctta gatcctggat ggtttctttt ttcacccaat
    11521 gggtgttttt tactagacaa aaaagagttt cccctttatg gtataagtgt agaaaaaaac
    11581 acaaaaagaa aggaaactca tatgaacagt ttaccaaatc atcacttcca aaacaagtct
    11641 ttttaccaac tatctttcga tggaggtcat ttaacccagt atggtggtct tatctttttt
    11701 caggaacttt tttcccagtt gaaactaaaa gagcggattt ctaagtattt agtaacgaat
    11761 gaccaacgcc gctactgtcg ttattcggat tcagatatcc ttgtccagtt cctctttcaa
    11821 ctgttaacag gctatggaac ggactatgct tgtaaagaat tgtcagctga tgcctacttt
    11881 ccaaaattgt tggaaggagg gcagcttgct tcacagccaa ccttatcccg ttttctttcc
    11941 agaactgacg aggaaacagt ccatagtttg cgatgcctca accttgaatt ggtcgaattc
    12001 tttttacagt ttcaccagct aaaccaactc attgtagata tcgattctac ccatttcaca
    12061 acttatggca agcaagaagg tgttgcttat aacgcccact atcgtgctca tggctatcat
    12121 cctctttatg ctttcgaggg gaagacaggt tattgtttca atgcccagct tcgtcctggt
    12181 aatcgttatt gttctgaaga ggcagacagc tttatcacac ctgttttaga acggtttaat
    12241 caacttctct ttcgaatgga tagtggcttt gcgaccccaa aattatacga tttaattgaa
    12301 aaaacagggc aatactacct cataaaactc aagaaaaata ctgttctgag ccgtcttgga
    12361 gacctttccc tcccttgccc acaggatgag gacttaacca tcttgcccca ctccgcctac
    12421 tcagaaactc tctatcaagc aggatcttgg tcgcacaagc gtcgtgtctg ccagttctct
    12481 gaacgaaaag aaggaaactt gttctacgat gttatttctc tcgttacaaa tatgacgagt
    12541 ggaacaagcc aagaccagtt tcagctttat cgtggacgtg gtcaagccga gaatttcatc
    12601 aaggagatga aggagggatt ttttggcgat aaaacggata gttcaacctt aatcaaaaac
    12661 gaagttcgta tgatgatgag ctgtatcgcc tacaatctct atcttttttt caaacatcta
    12721 gctggaggtg acttccaaac tttaacaatc aaacgcttcc gccatctttt tcttcacgtg
    12781 gtaggaaaat gtgttcgaac aggacgcaag cagctcctca acttgtctag tctctatgcc
    12841 tattccgaat tgttttcagc actttattct aggattagaa aagtcaacct gaatcttcct
    12901 gttccttatg aaccacctag aagaaaagcg tcgttaatga tgcattaaag aacagtcgag
    12961 atgaaaaaat cgtgtgacgc accaagggag gagtctgccc ttttgaggaa atctagcgag
    13021 gaaaaacgat actggaacag cagaaagtaa aactgacctc atgaggagga agaaagtggc
    13081 tcatgaggtc aggggttttg taagttacat ctagttgaga gaggtatgaa tgatttgggg
    13141 tttcaataac ctaactaagt ttaattcagt tagatttact tgattttctt ggatgctata
    13201 atcaggattt ttatgtctag cttttttata gtaaaaatcg aaatcttttt ctgtaacttc
    13261 aagttgattc actatgtctt ttgatgagaa tttactattt atcaagttgt gagtcttttt
    13321 caattctaat tttgtgtcat aaattactat ac
//
LOCUS       DAVLMQ010000046        12828 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000046 DAVLMQ010000000
VERSION     DAVLMQ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12828
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.046"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            4..1137
                     /locus_tag="VXF95_001668"
                     /pseudo
     CDS             4..1137
                     /locus_tag="VXF95_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611423.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(1253..2056)
                     /locus_tag="VXF95_001669"
     CDS             complement(1253..2056)
                     /locus_tag="VXF95_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HEV1082185.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATVYHHTVDASTEEADLVSLRIVELLSRRGFRFSPATLIAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(2659..4038)
                     /locus_tag="VXF95_001670"
     CDS             complement(2659..4038)
                     /locus_tag="VXF95_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1082186.1"
                     /translation="MSEYWFSTNVDQIDEVDGKQCLIYSYYNVKASRNVEVLKGRSGT
                     KKGLDYWEPYAPQKQYEMERLPKNKYIGSSSTDRWDGIEKNVVFCDCKEYVSAFDLFF
                     YHYNFKKISTQRSKQDFIRLRSKPVADILKNNTSSYTRYKKEMVIDNVKVDDKVCEII
                     SEIMDESYTDIQILTHKLYSKGDDIKASKTIWMKKSGKEYSEAFAGTGEARIILLVND
                     IVNAQSNSLILIDEPEISLHPSAIYKFKEFLLQECLNKKHQIIITTHSTQLIKDFPRE
                     AVKLLVKNGEKVDVIENIDYQDAFFELGDVYHSRKMIYVEDRLAKYILEFVITHSGSE
                     NLKQNLVVRYIPGGANQIICNNILNSSYLDSDNHYFWLDGDQNTNVSESNNLMNYLEN
                     GVVISDKIPESDNKNLDDIIKLITGCPIKFNVSGNKGQKNNIELIAKQRSFIDYWAKY
                     VSYLPFPTP"
     gene            complement(4089..4253)
                     /locus_tag="VXF95_001671"
     CDS             complement(4089..4253)
                     /locus_tag="VXF95_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HEV1082187.1"
                     /translation="MGKIVAIDLFSGAGGTTSGLKKSGIDVQVAVEIDSVAVKTYKLN
                     NPEVSVIDME"
     gene            complement(4334..6985)
                     /locus_tag="VXF95_001672"
     CDS             complement(4334..6985)
                     /locus_tag="VXF95_001672"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HEV1082188.1"
                     /translation="MSKELSPKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEQGRKMSKSLGNGIDPMDVIEKYGADALRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVVHDNVTKVATGEAGNVTDRWILHNLNETIGKA
                     TANFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQYAEGSIVTAAYPTVNPAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ECDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(6978..7556)
                     /locus_tag="VXF95_001673"
     CDS             complement(6978..7556)
                     /locus_tag="VXF95_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1082189.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQSLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKYKPLKRHIEVSEREIIETAETLQLNSQHQPNELNH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(7556..8116)
                     /locus_tag="VXF95_001674"
     CDS             complement(7556..8116)
                     /locus_tag="VXF95_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082190.1"
                     /translation="MARTELPDKIETECLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSVDFNHRHEDDVLEIGY
                     TLHPDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYAFLKSEWEVI"
     gene            complement(8103..8552)
                     /locus_tag="VXF95_001675"
     CDS             complement(8103..8552)
                     /locus_tag="VXF95_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HEV1082191.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVVPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(8964..9359)
                     /locus_tag="VXF95_001676"
     CDS             complement(8964..9359)
                     /locus_tag="VXF95_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1082192.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQSAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASDFK
                     NWTEKELLTLKGIGPATIKKLKENGIKFK"
     gene            complement(9455..9709)
                     /locus_tag="VXF95_001677"
     CDS             complement(9455..9709)
                     /locus_tag="VXF95_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HEV1082193.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKAGKGFHDLPEGLFGERNY"
     gene            complement(9719..11053)
                     /locus_tag="VXF95_001678"
     CDS             complement(9719..11053)
                     /locus_tag="VXF95_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HEV1082194.1"
                     /translation="MTDERIHILRDILLELHNGASPESVQDRFDATFTGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVLDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYELMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQSFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKDDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKTIMKGLREGSKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(11053..11286)
                     /locus_tag="VXF95_001679"
     CDS             complement(11053..11286)
                     /locus_tag="VXF95_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HEV1082195.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            11317..11394
                     /locus_tag="VXF95_001680"
                     /pseudo
     CDS             11317..11394
                     /locus_tag="VXF95_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(11600..11740)
                     /locus_tag="VXF95_001681"
     CDS             complement(11600..11740)
                     /locus_tag="VXF95_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082196.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(11737..11919)
                     /locus_tag="VXF95_001682"
     CDS             complement(11737..11919)
                     /locus_tag="VXF95_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082197.1"
                     /translation="MGLIKTLAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(11921..12700)
                     /locus_tag="VXF95_001683"
     CDS             complement(11921..12700)
                     /locus_tag="VXF95_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082198.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIEGE"
BASE COUNT         3855 a         2728 c         2328 g         3917 t
ORIGIN      
        1 ggaatagagt tcggcaaaaa aggaaaaaat cgttactatt ctcctgattt aaaacaagaa
       61 atgattcata aagtctgaca tgaaggctgg actaaagata gagtttctct tgaatacggc
      121 ctcccaagtc gtacgatact tcttaactgg ctagcacaat acaggaaaaa cgggtatact
      181 attgttgaga aaacaaaagg gagagtacct gagagcggag aatgccatcc taaaaaagtt
      241 aagagaactc cgattgaagg aggaaaaaga gaaagaagaa agacagaaat tgttcaagaa
      301 ttaatgactg agttttcgtt agttcttctt ctaaaatcca ttaaactagc tcgttcgacc
      361 tactactatc acttgaaaca gctagacaaa acagataagg accaagagct taaagctgaa
      421 attcaatcca tttttatcga acacaaggga aattatgctt atcgtcggat ttatttagaa
      481 ctaagaaatc gtgcttatct ggtaaatcat aaaagagttc aaggcttgat gaaagtactc
      541 aatttacaag ctaaaatgcg acagaaacga aaatattctt ctcataaagg agacgttggc
      601 aagaaggcag agaatctcat tcaaggccaa tttgaaggct ctaaaacaat ggaaaagtgc
      661 tatacagatg tgacagaatt tgccattcca gcaagtactc aaaagcttta cttatcacca
      721 gttttagatg gctttaacag cgaaattatt gcttttaatc tttcttgttc gcctaattta
      781 gaacaagtac aaacaatgtt ggaacaggca ttcacagaga agcactacga gaatacgatt
      841 ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt tcttgagggt
      901 aagggaattc aagcatccat gtcacgtaag ggaaacagcc aagacaacgg tatgatggag
      961 tccttctttg ggattctgaa atcggaaatg ttttatggct atgagaaaac atttaaatca
     1021 cttaatcaat tggaacaagc tattgtagac tatattgatt actacaacaa taaacgaatt
     1081 aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt cggataaatt
     1141 atttgtctaa ctttttgggg tcagtacacc taaaactttg atgatatacg ttttcttgtg
     1201 agaatattta cttcattttt gcctaaaatt caatgtttac tcagtatttg gattatgaaa
     1261 aatcgaggtc taaatctaga tacatttttt ctgaagacaa atcattttga ccaccgagca
     1321 agagattttc aaaaaaagct gttaaaaact caggacgtcg ctgtaaaatc tttgcattat
     1381 ctaataccaa ggcatcacga aaatacttgg aatgttgctg aaatggtata ttatcaatat
     1441 caaaaccaaa ctcacgaaga tactgaatca aaaagaccgt tactgtccga gtgtttcctt
     1501 cgcgaaatgg atgaatctgc cagattcctg aaataaaatg ctggatttgt ttaaccacat
     1561 ccgcctgagt tagtgtcgca tatgcaactt gtttttcctg attaaaatca taatccaagg
     1621 tcatttgaat catggagtaa tcagagtaca caacactttc accattcaaa acaggttcat
     1681 tctttgtgat attggtctga cgaaattgcc ccaccggaat agagggttca aatatatctt
     1741 gaaacaactc cttatgaata gcaattaaag tcgcaggact gaatctaaaa cctcttcgag
     1801 acaagagttc tacgatacgc aaagaaacca agtctgcctc ctccgtactc gcatcaacgg
     1861 tatgatgata aaccgttgca tcctcataaa cctgctcata agtcagttca ccccgggact
     1921 gtttctcagc caaagattcc atatacgctg atggcactag attgtcaact ttctgcagac
     1981 caaaacctat ccgccataaa tcacgcttcg cttcataaga caagtttgga ttgtcaatgt
     2041 tgtaagttga ttgcatagaa atatcctttc aattgttttt ctgtgtcatc ggtaaattgt
     2101 gaaataggta tggaattggc gaaaattata aaaatccttc acaataggtt ctatgaaata
     2161 tatatacttc atcttaatag tgagcaagct aaacttagca tttcatgccc tcatatggga
     2221 tgttctttga ctaaataata tgattatcga gatatatctg gataaatgaa ctaataagtc
     2281 tgacgcgtag acttatcaaa gtcattggca tacaccacta tgaactcgtt ggtctgttca
     2341 aatcccaaca cattacctga gaagaaagtt gcaatgttgt ttttggtgcg ggtttgaatt
     2401 taaaaatttg ttatgtagta cctaatctaa ggaattagaa caatgcctct aatttttctt
     2461 taatacactg aaacattgat gattctggct gtatttttga aacagctctt ctttgctcct
     2521 ggaaaatatc ttcagaagtt atattctcta ttcctaacgc tacttgaatt tttttctaaa
     2581 atattctttt ccgttgccat ctttagaaaa atcataacct tccctatcta cgctgttaca
     2641 taaattagct aaaaaaaact atggggttgg gaaaggaaga taagaaacgt atttagccca
     2701 ataatctata aagcttcttt gtttcgcaat taattcaata ttattttttt gccctttatt
     2761 acctgaaaca ttaaatttaa ttggacatcc cgttatcaat tttataatat catcaagatt
     2821 tttattatct gattcaggaa ttttatctga tataacaaca ccattttcaa gatagttcat
     2881 taaattattt gattcactaa cattagtgtt ttgatctcca tcaagccaaa aataatggtt
     2941 atcggaatct aaatacgatg agtttaaaat attattacaa attatttgat ttgctccacc
     3001 agggatatat ctcactacta aattctgttt aagattctca ctacctgaat gagtgataac
     3061 aaactctaga atatatttag ctagtctatc ttcaacataa atcatcttcc tagaatgata
     3121 cacatcacct aattcaaaaa atgcatcctg ataatcaata ttttcaataa catctacctt
     3181 ttctccgttt ttcactaaaa gtttcacggc ttctctagga aaatctttta taagttgtgt
     3241 agaatgtgta gtgataataa tttgatgttt tttatttaaa cactcttgaa gtaaaaactc
     3301 tttaaattta tagattgcac tcggatgaag tgagatttca ggttcatcta ttaatattaa
     3361 tgaatttgat tgcgcattta ctatatcatt tactaacaaa ataattctag cctcacctgt
     3421 tcctgcaaaa gcctcagaat attcttttcc agattttttc atccaaatag ttttggaagc
     3481 ttttatatca tcaccttttg aatacaactt atgtgttaaa atttgaatgt ctgtataaga
     3541 ttcatccatt atttcactaa taatttcaca aactttatca tcaactttaa cattatctat
     3601 aaccatttcc tttttataac gcgtatagct acttgtatta ttctttaaaa tatcagcaac
     3661 tggtttagat cgtaatctta taaaatcttg tttactacgt tgagtagaaa tttttttaaa
     3721 attatagtga tagaaaaata aatcaaaagc agaaacatat tctttacaat cacaaaagac
     3781 aacatttttt tcaatgccat cccatctgtc tgtcgaagaa cttccaatat atttattttt
     3841 gggtaatctt tccatctcat attgtttttg aggagcatat ggttcccaat aatctaatcc
     3901 tttttttgtt ccagaacggc ctttaagaac ttctacattt ctagaagctt taacgttata
     3961 atatgaatag attaaacatt gtttcccatc cacttcatct atttgatcaa catttgtact
     4021 aaaccaatat tcagacacac ttttattggc tggagaacca tataaagctt gtaaaattga
     4081 agttttattt actccatatc tattacagac acctcaggat tatttaactt ataagtttta
     4141 acagctacgg aatcaatttc aacagcaact tgaacatcta tgcctgattt tttaaggcca
     4201 cttgtagtgc cacctgcacc gctaaataaa tcaatagcaa caattttccc catagtattc
     4261 tcctaaagtt tctccttttt attataacat tatcaaatgt aaaacccaac ccgagagggt
     4321 taggttttta acatcatttc accaacttct tcatctcatc aatacgtgcg acggtcgcgt
     4381 catatttagc ttggtagtca gcttgtttgt cgcattcttt ttggacgact tctggtttgg
     4441 cgttggctac gaagcgttcg ttagagagtt tcttaccaac catgtccagt tctttttgcc
     4501 atttagcaag ttccttgtcg agacgggcca gttcttcttc aacattgagg agatcggcca
     4561 gtggcaggta gatttctgct cctgtgatga cacttgacat agccagttca ggtgcaggga
     4621 tggttgatgc gatttccaaa tgttctggat ttgtaaagcg tttgatgtag ttgacattgc
     4681 tgttaaagaa ggcttccaag tcgctatcgc ttgtcttaac aaggatggtg ataggtttgc
     4741 ttggtgctac atttacttcc gcacgcgcat tacgaacggc acggatcaag tctttgagac
     4801 tttccacacc agtgtgggca gcaaggtcct caaaggctgg gttgacagtt gggtatgctg
     4861 ctgtcacgat agagccttca gcgtactgac caaagatttc ttctgtcacg aatggcatga
     4921 ttgggtgaag aagacggagg attttatcca gcgtatagag gagaacagat cgagtaatga
     4981 ccttatcgtc ttcattgtcg ctgtaaagaa cttccttggt caactcaaca taccagttgg
     5041 caaattcttc ccaaatgaag ttgtagagga tgtggccagc aacaccaaac tcaaacttat
     5101 caaagttagc agttgctttt ccaatcgttt cattgaggtt gtggagaatc cagcggtccg
     5161 tcacattacc agcctcacct gttgcaactt ttgtgacatt gtcatgcacc acatccagcg
     5221 tcaaaccttc attgttcata aggatgtagc gagagatgtt ccagatcttg ttaatgaagt
     5281 tccatgaagc atccattttc tcataagaga aacgcacgtc ttgtcctggc gcagaaccgt
     5341 ttgaaaggaa ccatcgaagg gcatcggcac cgtatttctc gataacatcc attgggtcaa
     5401 tcccgttacc gagagactta gacatcttgc gtccttgctc gtcacgaata agaccgtgga
     5461 taaggacgtt ttggaatggt tgacggcctg tgaattccaa tgactggaag atcatacgag
     5521 acacccagaa gaagatgatg tcgtaacctg ttaccaaggt tgaagttggg aaataacgtt
     5581 taaagtcttc tgagtcgact tcaggccagc ccatggttga aaatggccag agggcagaac
     5641 tgaaccaagt atccaagacg tcttcgtcct gagtccatcc gtcaccttct ggagcttctt
     5701 cgccgacata catttcacca tcagcattgt accaggcagg gatttggtga ccccaccaaa
     5761 gctgacgaga gataacccag tcgtggacat tttccatcca ttgaaggaag gtatcgttga
     5821 aacgaggtgg gtagaattcg accttgtcct ctgtgtcttg gttggcaatg gcgttcttag
     5881 ccaattggtc catcttgacg aaccattgag tagacaagcg tggctcaact acgacacctg
     5941 tccgttctga gtgaccgact gaatggacac gtttttcgat tttgacaagg gcaccgattt
     6001 cttccaactt agcaacgact gccttacgag cttcaaaacg atccatgcct gaaaattcaa
     6061 aggcaagctc attcatagtt ccgtcgtcgt tcatgacgtt gacttgtggc aagttatgac
     6121 gttggccaac caagaagtca tttggatcgt gggcaggtgt gattttcacg acaccagtac
     6181 caaactcagg atctgcgtgc tcatctccaa cgattgggat gagtttatta gcgattggaa
     6241 ggatgacgtt tttaccaatc aagtccttgt agcgcgggtc ttctggatta accgcaaccg
     6301 caacgtcccc aaacatagtc tcaggacgag ttgtagcaac ttcaagggcg cgtgaaccat
     6361 cttccagcat gtaattcatg tggtagaagg caccttccac atccttgtga atcacctcaa
     6421 tatcagaaag ggctgtgcga gctgctgggt cccagttgat gataaactca ccacggtaga
     6481 tccagccttt cttgtaaagg tccacaaaga ccttacgaac agcttttgac aaaccttcgt
     6541 caagagtgaa acgctcacga gaatagtcta cagagagccc catcttgccc cattgttcct
     6601 tgatggtagt ggcatattcg tctttccatt cccagacttt cgtcaagaaa gactcacgac
     6661 caaggtcata gcgggaaatg ccctcaccac gcaagcgctc ctcaacctta gcctgagtcg
     6721 caataccagc gtggtccatt cctggaagcc aaagggtatc aaaaccttgc atgcgttttt
     6781 gacggatgat aatatcttgc aaagttgtat cccaagcgtg accaaggtga agtttacctg
     6841 taacgtttgg tggtggaata acgattgaat aaggcttagc cttttgatcg cctgaaggct
     6901 tgaaaacatc agcatcaagc catttttgat aacgaccagc ctcaacctcg gctggattgt
     6961 atttaggtga aagttcttta gacatgtgtg tgtcctttct ctattttgtt tattttattt
     7021 tgaatttgct tagcagcttc ttctgcagac aaattcgtat tatttatttt aaagtagtgg
     7081 ttcaactcat tcggttgatg ttgggaattt aattgaagtg tttcagcggt ctctataatt
     7141 tctctttcag atacctcaat atgtcgtttt aagggtttgt actttaatcg attctccgtt
     7201 cgatttcgac gtatgcactc ttcaagactt gtttccaact caacaaaaag aatctcttga
     7261 tgataatcat ccaacaaact ctgaatttgc tttaaatata tcagatgata ctgatttgaa
     7321 aaatcaatta catctgttaa aattactgat cgctgatttc ttgcactcgc tccaaggaat
     7381 gaaaaagtga ttccacgaac aaattcccac atttcctctg tatagtcctg atagatttct
     7441 agtgcaaaat caatggcttg atggttataa aagagggtag catccgtcag tcgagataat
     7501 tcttgaccaa tggtcatttt tcctgatgct ggagcaccaa tgatgaaaag atgcatcaaa
     7561 tcacctccca ctcactcttc agaaaggcat atctcaaatc atcacagcag ttgccttgag
     7621 catctttgcg gtctcttatg cgagcttcga gggtaaagcc aagtttttcc gcgactcgtt
     7681 gactttgaag gttatatcca aagcaagtta gttcaatctt gtgaagaccc aaatctttaa
     7741 aggctaagtc aatcaaggca cgcgcagctt ctggcacata acctcgcccc caatagtctg
     7801 ggtgtaaggt atagccgatt tccagcacat catcttcatg gcgatggttg aaatcgacag
     7861 agccaacgat cttatccgtt cctttgacga caatcccgta gcctgctggg agattttcct
     7921 tttgattacg ctccggaaga atgtgctcca gataataaat ctcatcttcc aaggtcttga
     7981 ctggaggaaa acctgctgga taggcgacct ctggcaaact agcatagtca aagatatcct
     8041 cagcatccgc cacagtacgg actcgtaaaa cgagacattc tgtttcgatt ttatctggta
     8101 gctcagttct tgccatcctt cttcctcgct tttttgatga aactgccctt catatctaca
     8161 cgcttgtcca gatagcgata aacgcgctga tatccatctc ccatgaaata ggttggggca
     8221 aacagttgat ttttaaaatg tcccttttca tccaggagtt ctggaacaac aagtcgctca
     8281 agaatcttgg caaagatgtg gcaaataccg tcttcctcaa caatcctatc tacccgacaa
     8341 tctaaaacaa gtggacaggc gtctaaaata ggagtctgag ttcgttcaga aatttcataa
     8401 tgcactccca aacgttccaa tttctcctga tgactgataa aaccagcctg ctccatcgca
     8461 agcatagaag tttcatcaga aatattcaca gtaaattttt gatactgttt gatctgctct
     8521 gcggcattct ctctcgcaac gactccaatc acaacccaat ctcctagact ataagaggaa
     8581 ctacaggtcg tgatgttata gccaaaattc taatcttgat atcctaaaat aaaaacagga
     8641 aaaccataat atagtttact tgtgttaaaa gattgcttca taacaacccc ctttgactaa
     8701 gacgtaaaag aaaagccctg ccatctacat gacagggacg aatgtgttta tccgcggtac
     8761 cacccaattt cgggccaagc ccgcatcttt agtctttaaa ataaaaagac agaaatattt
     8821 cattttttca gtcattagca accagttttg acacatttgt ggacttctca gcgccgccac
     8881 tttctgtaaa atgtgggatt caaaacacct ctaatggctc tattgtagca agtttttctc
     8941 ggaaatgcaa ggctcaaaaa aaattacttg aacttgatgc cattttcttt caatttctta
     9001 atggtagctg ggccgattcc tttcaaggta aggagttctt tttcagtcca gtttttgaaa
     9061 tctgaagcag acttgattcc ttcatcatag aaagtcttgg cacgatcaag tggaagtcca
     9121 cccaagtttg ctgcaaaatc ttctacagaa ttagctactt tttgagcttg ctctttggta
     9181 gcttctactg cttgttcaac ttttttagaa acagccttac cagctgcgct tgctgactgt
     9241 tctgcacgct tcacgacttt ttttgtctca tctacaacct tagtcacagt acttgaaaag
     9301 gcacctgcgc gacggaggcc atttcgtaat tgttttttac gattgagttt ctttgacatg
     9361 ataaaatcct ttcaataaaa aatccctgct ctgacaagga tttaacataa acattctatc
     9421 aagattttag tgaaaaatca agaatctttc tcgtttaata atttcgctca ccaaacaagc
     9481 cttctggcaa atcatggaat cccttgcctg ctttgaagtt ttcaaactta ccaagcaaga
     9541 actgataagc atccaagcga ctctcgtagc gaatcatggc atctttggca cgctcgtcct
     9601 ggtcttcttc gtaaactttt tgactttcct tgtgcgccat gtcgttaatc atgatttggg
     9661 tattgaccca agcttcaaat tccttcataa attcttgttc gtaactcatt ttttctcctt
     9721 attctaatcc acgaaaatag tccgtatcaa tctcacggta gggctggata tcctgaacat
     9781 actccaacac tccttggaat tctccgtctt catcgtgtac tgcagcatag gtgatgtgga
     9841 caaacttacc tcgcgactca gacttgaacc acatttcata cttgtctttg cttccctcac
     9901 gaagcccctt catgatagtt ttgaccttgt ccaagtactt aggcggatgg cagagttcga
     9961 cattgcgccc gacttgagac ggcgtccgtt tgaaaatcat ctcatcagct ggcgtattgt
    10021 cattgtaata ctggaaaata tcatctttat tgacaaaggt aatctccata gggaggtgat
    10081 tgaggatgag attggcctgc tcgactgaaa gatagccatt accaaaagcc tgttgactat
    10141 ggcggtccag cacagcttcc ttttccttag gggtaaaggt aatggtaaaa tggccttctg
    10201 gcgtatctat gacttgttga acttgacctt ctgccgtatc tagctgtaca ggctcctctg
    10261 caatcttttc ctcaataaag ctctgtcgtt ctggcaccca tttctctgac ggacggatga
    10321 tggcatagcc ataggcatcg ctctcctccg caatctgaag ccagtcatcc tgagtaaaag
    10381 actcaaggag aatcatgagg aggatggact cttccttgaa aatcatactt tcaaactctg
    10441 tcgcaaaagc ttcaaaagct tcctttacac tgctaattga cacttctggt agtgacttgg
    10501 ctgtcgttag agctgtttga aagagttccc taatctgatc atccactccc cacataactt
    10561 tgggaggtga atcgtgtcca tagcgctcca tgataggaaa gaagagttct tctttacgtt
    10621 ggtaatggat gtcaaattgc cccacaagtc ccatctgacg caccaagccc ttgcgcatct
    10681 ccgcaagcat ttcctcgtct tccatcaact cataggtatc taacaatcta cgaatgcgaa
    10741 tcaaagctgc acggagggcc aaattttctt ccttaaagac acgaactggg tgcccagggt
    10801 gttcggtatc taaaacttcg acacctttga tagcattttt aaaaagattg gcatggacat
    10861 cacagagttc cataacatct tcaaaagtga cgcccgaatc cgagttcatc agctcgtgct
    10921 ccataaggga aatctcgatg gctgacacgc ccgtaaaggt cgcatcaaag cgatcttgaa
    10981 ccgactcagg agaggcgcca ttgtgcaatt ctaacaaaat atcccgtagg atatgaatcc
    11041 gttcatctgt cattagtcta atccaatcac ttcgtagcca ttcgcttcca gtgtgcgtac
    11101 aatcttgtcc ataggagttc ctgctagctt agaaccctgt ttaagtgata ctttacgacc
    11161 aactgtattg cgcattaagg gattggcaag gggtttaaaa cccaactcca ctagaatttc
    11221 caagacttct ggatgcttgt ccaccacttc tgcaacagga attgacacat cgatgatatt
    11281 gtccatgacg acctccattg tatgttctaa tactcaatga aaatcaaaga gcaaactagg
    11341 aagctagccg caggttgctc aaaacagtgt tttgaggttg tagatagaac tgacgaagtc
    11401 agctcaaaac accgttttga ggttgtggat agaactgacg aagtcagtaa ccatacctac
    11461 agcaaggtga agctgacgtg gtttgaagag attttcgaag agtataaaat gattttactg
    11521 cttatattat accatatgga aagagaataa aaaactagca gtggagttcc tgctagttct
    11581 ctgcgacttg gattaccatc tagataagtt taaagaacca atccaatatc ttgtaaaaca
    11641 gcaattggac tgcaaaagag atgatcatcc aaaagaattt cacaatccca ataatcggtt
    11701 tgataaaaat aatggcaaga agtccccaga aaaatttcat tttttatcct ctggcttaat
    11761 gagccaccga gccgtatcca ttaacttgtc ggcaataaaa agtttcccca gaccgacaac
    11821 ggcattatca tctttcttta tcgttttcat tacttttaca ccttgcacgg tcaaaaagta
    11881 attaccataa attttagcta gagtttttat gagtcccata ttactctcct tcgatgattt
    11941 cagcctcttt tcggattgtt tcaacatctt cttgatattg aacttcacta tagttaacta
    12001 gcttggacaa ttctttctgc aagctttcac ccatcggttt catagttgca aaggttaaac
    12061 cacctgaaat gataccaccc aagataggaa taaatttccc cattcctttg gccagccctc
    12121 ccttggtaag attcacacca aatattctta agactttttt caaaatagga taccaaagcg
    12181 tctttgttaa agctttatta ggtactgttt tcattacctg tttggcaatt gttataccac
    12241 cagcacgtag caaagcagca gttccattca cccccaacat gacgcctaga taaagcaaaa
    12301 gggtattttg agcatcttca ctcaactcat cgcgtgaagc ccaaagatcc tcataaccat
    12361 aaatataacc taattcttgg gccaatttca gagagaaacc ataaaattga gccacatcag
    12421 ctggaatggt aattgccata gcaagccctc caggtaatcc tgccaaaaca gaagtcccac
    12481 tcgctaataa aacattatcc ctaatacagg cattagccac tcgatctaag atttcttgag
    12541 ataagagaga cgttggacct tgttccaata aggtaggaat gtcctgtgga cccaattctt
    12601 tggaaaactt atccactaaa aatttcgaac gatcaacctt aacaacaggt agtttcacca
    12661 cttgttgcaa tacttgcata gctaagtctt gttcagccat atacaaactc cttatttctt
    12721 ttttgcacct tatcatatta tatttcctac aaaaaaagca ttttctaatt agataacatt
    12781 aaaaaataca gaatcccttt tttatattaa aacgaaacaa gaacagga
//
LOCUS       DAVLMQ010000047        12793 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000047 DAVLMQ010000000
VERSION     DAVLMQ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12793)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12793)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12793
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.047"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..319)
                     /locus_tag="VXF95_001684"
     CDS             complement(<1..319)
                     /locus_tag="VXF95_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HEV1082199.1"
                     /translation="MQYSCGKININIPDGYGDIKDIVFSAHIIVRYNNGHCGGIDPHI
                     IGLCKKQIRRMSLYPILIIVSRDSKVIDDYKNLDIAYVDCTQCSNNFETALHVKNILK
                     LLKI"
     gene            562..855
                     /locus_tag="VXF95_001685"
                     /pseudo
     CDS             562..855
                     /locus_tag="VXF95_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            962..1313
                     /locus_tag="VXF95_001686"
                     /pseudo
     CDS             962..1313
                     /locus_tag="VXF95_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1589..2895
                     /locus_tag="VXF95_001687"
                     /pseudo
     CDS             1589..2895
                     /locus_tag="VXF95_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(2935..3945)
                     /gene="tsaD"
                     /locus_tag="VXF95_001688"
     CDS             complement(2935..3945)
                     /gene="tsaD"
                     /locus_tag="VXF95_001688"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HEV1082200.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDELAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLYHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(3935..4372)
                     /gene="rimI"
                     /locus_tag="VXF95_001689"
     CDS             complement(3935..4372)
                     /gene="rimI"
                     /locus_tag="VXF95_001689"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HEV1082201.1"
                     /translation="MIEIKRIQQQPDLAQAIYAVMAAVYLVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQETLFEAEVLQIAVKGAYQGQGIASALFAQLPTDKEIFLEV
                     RKSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            complement(4369..5052)
                     /gene="tsaB"
                     /locus_tag="VXF95_001690"
     CDS             complement(4369..5052)
                     /gene="tsaB"
                     /locus_tag="VXF95_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HEV1082202.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQVLAETTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAYTLNIELVGMSSLLALVPY
                     QQEGLFVPLMDARRNNVYAGFYENAKPVMAEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQKHLPRTDYKETLPNAANLALLAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            5231..5416
                     /gene="cibA"
                     /locus_tag="VXF95_001691"
     CDS             5231..5416
                     /gene="cibA"
                     /locus_tag="VXF95_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HEV1082203.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKVIAGG
                     TALIGSGLAAGYFLGGD"
     gene            5418..5570
                     /gene="cibB"
                     /locus_tag="VXF95_001692"
     CDS             5418..5570
                     /gene="cibB"
                     /locus_tag="VXF95_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HEV1082204.1"
                     /translation="MMKDLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(5893..6108)
                     /locus_tag="VXF95_001693"
     CDS             complement(5893..6108)
                     /locus_tag="VXF95_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082205.1"
                     /translation="MYNLFAFAIGARLVAFIVFVACVYAGNLLFAKLERRQTKFLWKM
                     TFVTLYSLFLLLVTYVVWFVFYFELNA"
     gene            6388..6621
                     /locus_tag="VXF95_001694"
     CDS             6388..6621
                     /locus_tag="VXF95_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HEV1082206.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDTSSELEGRITARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFEITEF"
     gene            6623..8302
                     /locus_tag="VXF95_001695"
     CDS             6623..8302
                     /locus_tag="VXF95_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HEV1082207.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     VCTGDFKFDFTPVGEPADLHRMAALGEEGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEVLILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLCLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(8400..8477)
                     /locus_tag="VXF95_001696"
                     /pseudo
     CDS             complement(8400..8477)
                     /locus_tag="VXF95_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(8681..10594)
                     /gene="mnmG"
                     /locus_tag="VXF95_001697"
     CDS             complement(8681..10594)
                     /gene="mnmG"
                     /locus_tag="VXF95_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HEV1082208.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEAPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
     gene            complement(10604..11059)
                     /locus_tag="VXF95_001698"
     CDS             complement(10604..11059)
                     /locus_tag="VXF95_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HEV1082209.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALIVQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVREELGVKAQAGQLAFVVENRFEVDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            complement(11200..12321)
                     /gene="mnmA"
                     /locus_tag="VXF95_001699"
     CDS             complement(11200..12321)
                     /gene="mnmA"
                     /locus_tag="VXF95_001699"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HEV1082210.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAITLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKALSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTCDMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
BASE COUNT         3649 a         2981 c         2519 g         3644 t
ORIGIN      
        1 ggatttttaa taattttaaa atatttttaa cgtgtaaggc agtttcaaaa ttatttgaac
       61 attgagtaca atcaacatag gcaatatcta aatttttata atcatcaata acctttgaat
      121 ctctagatac gattatcaaa ataggatata gagacatcct tctgatctgc tttttacaaa
      181 gtccaattat atgcggatct atacctccac aatgtccatt attataccta actataatat
      241 gagccgaaaa cactatatcc ttaatgtctc catatccatc agggatatta atatttattt
      301 ttccacaact atattgcatt gtaaccatct ccttaaacga cgcattatga tatttgatag
      361 agaaattttt atgaataact caataatttt atagtaaatc atgcttatat ctcaaagata
      421 cctattttct cttgtctcga ccttctccaa agaattgcta taatactatt acaaatacat
      481 ctgcactaca cttcaaattt tagcactgta taaaaacgtt tcaacacact aactttaaga
      541 aaacttccac tattaattga aaaagttgat agagataaat taaagatcta tattgaaact
      601 catcccgatg cttatttgac tgaaatagct gctgaattca actgtcctcc aacaactatt
      661 cattacgctc taaaggctat gggatatagt ctaaaaaaga gccgtaccta ctgcgaacaa
      721 gacccagaaa aagtaaatcg gttccttaaa gaattgaatc acttaagcta cctgactcct
      781 atttatattt atgagacagg ggttgagacc tatttttatc tcgaatatga tcgagccttg
      841 agcaggcagt tagtctctct ggaagaagat ataattattt gaattaagat cgagacaacg
      901 cacaccagag attgcgatac tgttatagaa gtactaatgc ccttttttgt ttcaatatac
      961 tatggctccg atgacctata aagatacgat gacgagtgac tttttcgaag cttgcttcca
     1021 aaaattctta ctacctactt tagatacacc atcccttatc attatggaca atgcaaggtt
     1081 tcacagaatg aacatgtgta aggagcaggg catagactgt taccacttcc tacctattca
     1141 cccgagtata atcccattga gaaaatatgg gcttacatca aaaacatctc agaataatat
     1201 tgtcaaatta cgatgctttt cttgaggcac ttttgtccta ttcttgtttc agccgactat
     1261 actccgttat tgggcagcta cggaacagtc gatgggacga tggggggaca taaaaaaatc
     1321 ctccagtttt gttttttata acagtatact ggagaattga caatctcggt agatacctcg
     1381 ttatagcgcg gttacttatt aggcagttac aaaacaactg tgaacagaaa acattccaga
     1441 gtcagacaag actttggaat gctttggctc tataatttct gtagtgggta atcccacccc
     1501 aggaattata gggtcgtttc ttgtagaaaa aaagccccat atgacctata atgaaaagcg
     1561 tctaaccaac tcattagaaa gggtccatat ggaacaactt aagaatacca cagatttgct
     1621 cggattggaa gacaaaaata tcaaaatctt gtctgttctg aaataccaaa cccatctagt
     1681 cgttcaggca aagttggatt cccccgctcc tccttgtcct cattgtcaag ggaagatgat
     1741 caaatacgac ttccagaaag cctctaaaat tccgcttctc gactgtcagg gtttacccac
     1801 ggtactgcat ctcaaaaagc gccgctttca gtgcaagaat tgccttaagg tggtcgtttc
     1861 tcaaacatcc attgtcaaga aaaattgcca gatttccaac atggtgagac aaaaaatcgc
     1921 tcagctcctc cttgaaaagc agtctatgac tgagattgcc cacagattgg cggtctcaac
     1981 ttccaccgtc atccgaaaac tgagggaatt taagtttgaa accgattgga ccaagttgcc
     2041 aaaagttatg agttgggatg agtatagctt caaaaagagc aaaatgagct tcattgccca
     2101 agattttgag tccaaatcca tcctcgcaat tttagacggg cgaactcatg cggtgattcg
     2161 aaaccatttc caacgctatc agagagaggt tcgggagctg gtcgaggtca tcaccatgga
     2221 catgtacagc ccttattatc ggctcgctaa gcaactcttt ccaaaggcga agattgttct
     2281 tgaccgcttc cacattgtcc aacatctgag ccgagctatg aaccgagtac gaatccaaat
     2341 catgaaccaa tttgaccgaa aatccttgga gtatcgggcg ctcaagcgct tttggaaccc
     2401 tcgctttttc gtttctaggc tcgggctaaa tcagtccact ggactgattt actacaccag
     2461 gatagcttca agctctgtca gaaacgattc tatcagtcca cgtttcgaat gcacttaacc
     2521 catcgggaag tacgagataa gctgctttcc tactctgagg gattacaggt tcactacgaa
     2581 ctctatcaac tcctgctctt tcattttcaa gagaagaatg ccgaccattt ctttggattg
     2641 attgagcaag aactgccaac ggttcatccg ctttttcaaa cggtcttttg gactttttta
     2701 agggatagag ataagattat caacgcactt aagctgcctt attccaacgc taaacttgaa
     2761 gcgaccaata atttgattaa ggttatcaag cgcaaagcct ttggtttccg gaactttaac
     2821 aattttaaaa aacggatttt gatgactttg aacatcaaaa aagagagtac gaatttcgta
     2881 ctctccagat tgtagctttt cgcctaccca ctacacttga caaagagcca ctctttattc
     2941 catggtatca aaggcaagac ttggtttggc attgaggtcc cagcctgcga agttttcttt
     3001 gttccactcg ctgacgctgg cataggcaat catacctgca ttgtctccgc agagtcgcag
     3061 aggggggatg ataaccttga catctgtgat ttcggctgct aggcgttctc tgagaccttt
     3121 attggctgcc acaccacctg ccacaaccag ggttttaaca ggatatttct ccaaagcctt
     3181 cttggttttt gccatgagaa tgtccataac tgctgcttgg aaggaagcac acaaatcttc
     3241 tgtagacagg ctttctccct tttgctcggc attgtgataa agattgataa aggcagattt
     3301 caaacctgag aaggagaact ccagattatc ttccttaatc atggcacggg ggaaatcata
     3361 aatatcctgc ccctgatgag ccagctcgtc aatctcacga cctgcaggat aggtcaagcc
     3421 catgacacgg ccgaccttat cataagcctc accaaccgca tcatcacggg tttccccaac
     3481 aatcttataa tctcctgcct ccgaaacata aaccaactct gtgtgtccgc cgctgaccaa
     3541 gagggctagc aagggaaact ccaaaggctc cacactctga gctgccatga ggtgcccagc
     3601 catgtgatta acaggaatca gtggaagtcc gtgagcccaa gcaaaggcct tggcagctga
     3661 caaaccaact agcaaggctc cgaccaagcc tggtccgtag gtaaccgcaa cagctgtcac
     3721 gtcctcttcg gtaatccctg cttctgccaa tgcctcctcg atacaggctg taatgacctc
     3781 gacatggtga cgactggcta cttcgggcac tacgccacca aaacgtttgt gactctcaat
     3841 ttgactagca atgacattgg acaagagctc atcgtcgttt ttcaagacgg cgacactggt
     3901 ctcatcacag gatgtctcaa atgctaaaat atatctatcc ttcatctatt tctctcttca
     3961 tgataatggc gtcctcgact gggtcatggt agtaggcctt tcgctcagcg atgaccgcca
     4021 ttttttcttt cttgtaaaat gcttgcgctc gttgatttga ctttctgact tcgaggaaaa
     4081 tctccttatc tgtcggcaat tgagcaaaca aggctgacgc aattccctga ccctgataag
     4141 ctcctttgac agcgatttgc aggacttctg cttcaaagag agtctcctgc acagctagaa
     4201 atccaatcac ttctgcccca tcataagcca atgcatacca agtctggtct tgggacagat
     4261 ctgcttggat ttgctccaga gtccaaggac tgactaggta aacagctgcc ataacagcgt
     4321 agatggcttg agctaggtca ggctgttgtt gaattcgctt gatttctatc ataggcgttt
     4381 aatgtaggac tcaccagact cggtatggtt cttgagccag ttttcctctg cctcaacacg
     4441 tttgaggtaa tttggcacaa aatcatgcaa ggagtctgct tccttgtccc aggccaaaag
     4501 agctagatta gctgcattgg gcaatgtttc tttgtaatca gtccttggca agtgtttttg
     4561 aatctgctca acaaaggggc caacttctcc gacaaaggtt acctgactag cgcccttgat
     4621 tagctcaatg actcgctcaa aaggcagatg tgcttctgcc atgacaggtt tggcattttc
     4681 ataaaatcct gcataaacat tattgcgacg cgcatccatc aaggggacaa acaaaccttc
     4741 ttgttggtag ggcaccagag ccaagagact cgacatacca accaactcga tattcagagt
     4801 ataagccaga gttttggcag tggctaccgc gattcgtaag cctgtatagc tacccggccc
     4861 ttcagctacc acgattcggt ccaagtcctt gggtgtccaa tccaaacttg ccatcaaaaa
     4921 atcgatggca ggcataaggg taatactgtg atttttctta atattaatcg tcgtctcggc
     4981 aagaacctgc ttatcctcta aaatagccag agaaagagcc ttgctggacg tatcaaaagc
     5041 taatactttc ataacacatt cctatctttt tgtctgctta ctattatact acaaaagctg
     5101 gcacatggga attttctttg cccccagaca agagtgccct cacttaacta aaaataattt
     5161 aaaaaaaatg ctcaattttc cttttctttt ccgaatataa aagtgaacaa gaaaaaagga
     5221 ggaaagttca atgacaaatt ttgacattct tgacaatcaa tttttatcct tatctgaaaa
     5281 tgaattatca gatattgatg gcggtctcgc tcccttagtt atctttggag tagcagtatc
     5341 ttggaaggtt attgcaggtg gaacagcact tataggttct ggtttggcag ctggttattt
     5401 tttaggagga gattaatatg atgaaagatt tgaacaatta tcgtgaaatt tctaataagg
     5461 aattgcaaga aatcaagggt ggctttggtg tcggtgttgg tatcgcttta tttatggcag
     5521 gttataccat tggaaaagac cttcgtaaaa agtttggtaa gtcatgctag ataagaaaca
     5581 catttttaga aggataaatt ttattgtctt catctcttac agtttgctca gcattctcaa
     5641 tgatttgaac attactacca tccctttacc attcgattta tctgtttgta ttgttttatt
     5701 tttatgcttc aactctattt ttgatcagaa caatgactcc cataaaaata ataagctttg
     5761 aaaattccat tgtcatgtca tgttagaaaa atgcaaagac cacctcatct tgatagatgg
     5821 ggtggaattt tcgtgtcgta aatctactat ctctacatcc ccaaacaaaa aaccccagca
     5881 taagcagggc atctaagcat ttaattcaaa gtaaaataca aaccaaacga cataggtcac
     5941 gaggaggaga aaaagcgagt agagagtcac aaaggtcatt ttccacaaga acttggtttg
     6001 tcgtcgttcc agtttggcaa atagaagatt ccccgcataa acgcaagcaa caaaaacaat
     6061 aaaagctacc aagcgagctc cgatagcaaa agcaaataag ttatacatag ggcaacctcc
     6121 ttgacttaaa atctatatgg aattatgaca agcaataaat ttcacttccg ttatcaacat
     6181 aatacatttt ctttgttttt gcaaacgctt accaaagaaa tcgtccccta actttctcgt
     6241 ttccgtcttt tactaatttt tcattttgtg gtataattga aataattgta acgaatcaag
     6301 gtcaatctag acacaaaatg gaatgaaatc aagcaaatat ctgctaaaag tttggaataa
     6361 gctgacctgt aaatagaaag gaactatatg atttacaaag ttttttatca agaaacaaaa
     6421 gaacgtagcc cacgccgtga aacaacacgc gcgctttact tagatatcga taccagctca
     6481 gaacttgagg gccgtatcac tgctcgccaa cttgtcgaag aaaatcgccc agagtacaat
     6541 atcgaatata tcgaactctt gtctgacaaa ttgctcgatt acgaaaaaga aactggcgcc
     6601 ttcgaaatta cggagttcta atatggccta cactcttaaa cctgaagaag tcggcgtttt
     6661 tgccatcggt ggtctaggag aaatcgggaa aaacacttac ggaattgaat accaagacga
     6721 gattatcatc gtcgatgctg ggattaaatt cccagaagat gacttgcttg gtatcgacta
     6781 tgtcattcct gactactctt acatcgtgga caatatcgac cgcgtcaagg ctgttttaat
     6841 cacacacgga cacgaggacc acattggtgg gattccgttc ctactcaagc aagcaaatgt
     6901 ccctatctac gctggaccgc ttgccttggc tttgatccgt gggaaactcg aagaacacgg
     6961 cctcttgcgc aacgccaaac tttacgaaat caaccacaac accgagttga cctttaaaaa
     7021 tctcaaggca actttcttta gaacgactca ctctattcca gagcctttgg ggattgtcat
     7081 tcatactcct caagggaaaa tcgtctgtac gggtgacttt aagttcgact ttactccagt
     7141 tggagaacct gcggacttgc atcgtatggc tgcgcttggt gaagaaggcg tgctctgtct
     7201 cctgtctgac tcgacaaatg cggaagtacc aacctttacc aactctgaaa aagtcgttgg
     7261 tcagtccatt atgaagatta tccaaggtat tgaaggacgt atcatctttg catcctttgc
     7321 ctcaaatatc ttccgtctcc agcaggcaac agaagctgct gttaagactg gacgcaagat
     7381 tgcggtcttt ggtcgttcta tggaaaaggc cattgtcaac ggaatcgatc ttggctacat
     7441 caaagcccct aagggaacct ttatcgagcc aaatgaaatc aaagattatc ctgcaggaga
     7501 agttcttatc ctctgtacag gtagtcaggg tgagcctatg gcagccctct ctcgtatcgc
     7561 caacggaacc caccgtcaag tacaattaca accaggtgat accgttatct tctcttctag
     7621 tcccatccct ggaaacacta ctagcgtcaa caagctgatt aacatcattt ctgaagctgg
     7681 tgtcgaagtt atccacggta aagtgaacaa tatccataca tctggacacg gtggtcagca
     7741 agagcaaaaa ctcatgctct gcttgattaa gccaaaatac ttcatgcctg tccacggtga
     7801 ataccgcatg caaaaagtcc acgctggact agcagtggat actggtgttg agaaggacaa
     7861 tatctttatc atgagcaatg gcgatgtgct tgcccttact gctgactcag ctcgtatcgc
     7921 aggtcatttc aacgcccaag atatctatgt cgatggaaat cgtatcggtg aaattggcgc
     7981 agctgtcctc aaagatcgtc gcgatctatc tgaagacggt gtcgttctgg cagtcgcaac
     8041 tgttgacttc aaatcgcaga tgattctatc tggtccagac atcctcagcc gaggctttgt
     8101 ctacatgaga gagtctggcg acttgattcg ccaaagccag cgtatcctct tcaatgccat
     8161 tcgtatcgca ctgaaaaata aggatgctag cgtgcaatct gtcaatggtg ccattgtcaa
     8221 cgctattcgc cccttcctct atgaaaatac cgaacgtgaa ccgatcatca tcccgatgat
     8281 cctcacacca gatgaagaat aatactcttc aaaccacgtc agcttcgcct tgccgtatat
     8341 atgttactga cttcgtcaat tctatccaca acctcaaaac tgtgttttga gctgacttcg
     8401 tcagttctat ctacaacctc aaagcagtgc tttgagcaac ctacggctag cttcctagtt
     8461 tgctctttga ttttcattga gtacaagtca acaaaacagc cccgtcttcg gagctgtttt
     8521 tctctatgct ttcttttgag attaaaactc aatgaaaatc agactagaag gctaagcgaa
     8581 agcataactt gagttagctc ccatagttcg ggaaactatg ggaggctgga gatgaatcaa
     8641 agccaagctt tgaactcatt cgtaagaagc cgacgacgta tcattttgat ttttgaagag
     8701 ttttagaaat actacgattt ttaccttcca gatacaccat caaaatagaa atatctgctg
     8761 ggtttactcc cgaaatacgg ctggcttggc cgatggtttc tggattgatg agtttgaact
     8821 tctgacgggc ttcggttgcg atagaatcaa tgtcatccca gtcgatattg gccggaatgc
     8881 gtttttcttc catgcgtttc atcttggcaa cctggtccat ggctttggaa atatagcctt
     8941 catacttgat ttctgtttca atcaattcga taatcttgtc atccaagtct tctgcagctg
     9001 gtccgatgaa ggccaccaca tcttggtaag aaacttctgg acggcgaagg aattccttgg
     9061 ctgtcaccgc atctgtcaac ggcttgaagc ccatttcctc aaccttagca ttggtttcct
     9121 tgactggctt gagtttgata ctgtctaggc gtttcatctc attatcaaat tgatttttct
     9181 tgatttcaaa acgagcccag cgttcatcgt ccacaaggcc aatctcgcgt cccatctcag
     9241 tcaagcgcat atcagcattg tcatggcgaa gaataagacg gtattcagca cgactggtca
     9301 agagacggta aggttcaatg gttcccttgg tcaccaagtc gtcgatcatc accccgatat
     9361 aaccgtcact tcgttttaga atcaattcag gcttgccttg gattttcaaa gccgcattga
     9421 tacccgcgat aatcccttgg ccagcagctt cttcataacc tgatgttcca tttgtctgac
     9481 cagcagtgaa gagacctgag attttcttgg tttccaaagt cgcacgcaac tgatgaggca
     9541 agaccatgtc gtactcaatg gcataacctg ttcgcatcat ctctgcattt tccaaacctt
     9601 tgatggaatg aaccaagtca cgctggacat cctcaggtag actggttgag aggccttgca
     9661 catagacttc ctctgtatta cgtccttctg gctcaaggaa gagttggtgg cgttccttgt
     9721 ccgcaaagcg cacaatcttg tcttcaatcg acggacagta acgaggcccc actcccttga
     9781 ccacacctgt aaacataggc gcacggtgga ggttgttttg gataatctca tgactggtac
     9841 cattggtgta ggtcaaccag catggcactt ggtccttgac ataatcctca tcacgtgaag
     9901 tgtatgagaa gtgattaggc gcttcatctc ctggttggat ttctgtcaca tcgtaattga
     9961 tagaagaagc cttgacacgt ggaggggttc ctgtcttgaa acgaccgatt tcgaggccca
    10021 gttccttgag attgtcagct aggttaatag aagccaagct gtggttagga cctgatgagt
    10081 acttgaggtc tccgatgata atttccccac ggagagcagt ccctgtcgtc acaataacag
    10141 ccttagcagc atattcttga tgggtggctg tacgcacacc gacaaccttg ccatcttcca
    10201 ccaaaatctc atcaatcatg gtttgacgaa gggtcagatt ttcttgattt tcaactgtct
    10261 tgcgcatctc cttagagtaa agttccttgt cagcctgcgc acgaagagca cggacagctg
    10321 gccccttccc tgtgttgagc atcttcatct ggatgtaagt cttgtcaata gtcttggcca
    10381 tctcgccacc gagggcatcg acttcacgca cgacaatccc cttggcagaa ccaccgatag
    10441 agggattaca aggcatgaaa gccagcattt caatattgat ggtcgcaagc aggaccttac
    10501 agcccatacg gctagcggcc aaggaagcct caaccccagc gtgtcccgca ccaattacaa
    10561 taatatcgta ttcttcagta aaatgataag tcatgtttct ctcctattcc tcaagatgaa
    10621 tgtgtcttag ttggccttcc caatctggta gggccgtttt taaaaaggct ggaactagct
    10681 ggatatcctc aagcttatcc aagtcaatcc actcacaggg ctgccttttc tcatcttcct
    10741 gcatggtcaa cggggcatct tcaagcaaat ccaccagata atgaaactcg atattgtgat
    10801 aggaaacgcc gtccacttca aaacgatttt caaccacaaa agctagctgc ccagcttgag
    10861 ctttaacacc cagttcttcc ctcacttcac ggactaccgc gtcttccgtg ctttcattga
    10921 cttgaatcgc acctccaata gtgtaatact tgcccttgtc tttggtaact agaagcttgt
    10981 gattttggac aatcaaggct gtcgcccgaa caccaaaaac cgtattgtct acttttgtcc
    11041 gaaagtcttg ttgagtcatt cttgtccttt cccttaaacg acacaaaaac agtcaaaact
    11101 acaaagaagt gcaggacaaa aaagcctgca acatccatga gctttgacca tcatttctat
    11161 tgctgttatt attgtagcaa attgagaaaa tttgtcaatc taaatgtact gacaaacttg
    11221 tccatcgcgg taagcattgt caatcaaacc gccacctaga cactcttcgc catcgtaaaa
    11281 gacaactgcc tgtcctggtg taatggcgcg ttgtggttcc gcaaagatga cctctgcctt
    11341 gtctcctttg acatggacgg tcaccttaga gtcaggctga cggtaacgga atttagccgt
    11401 acattctagc gtaaactcct cgggcatatc acaagtaaag tggacttggc tagcctctag
    11461 gctggttgac atgagcgaat catggtagaa tccttgtcct acatagagaa tattcttgct
    11521 tagagctttt ccgacaacga accaaggggc attgtcacca ccgtgttgcc caccgatacc
    11581 aagcccgcca cgctgaccaa tcgtatagta catcagacct gcatgctcgc ccatatcgcg
    11641 accatccaca gtcatcatgc gaccaggctg agctggcagg tagttgctga gaaagttttt
    11701 aaagttcttt tctccgataa agcaaatccc tgtcgagtct ttcttcttag cagtcgaaag
    11761 acctgcttct tctgctagtt ttcgaacttc aggcttttcc aaatgtccta gtgggaacat
    11821 ggttttttga agttgttctt gcgaaagttg gctgaggaaa taggtctgat ccttgccatt
    11881 gtccacgcca cgaagcatgt gaacggtacc atcctcatca cgcgccactc gagcataatg
    11941 cccagtcgct acatagtctg cccccaaggt tatggcatag tccaaaaagg ccttgaactt
    12001 gatttccttg ttgcacataa cgtccggatt tggcgtgcgc cctgcacggt attccgctag
    12061 gaaatactca aaaacgcggt cccagtactc tttttcaaaa ttgacagagt agtagggaat
    12121 gccaatctgg tctgccaccg caaccacatc cttgtaatct tcggtcgccg tacagacgcc
    12181 gttttcatct gtgtcatccc agttcttcat gaagataccg atcacatcgt agccctgctc
    12241 cttgagcaaa agagccgtca ccgacgaatc aacaccacca ctcatcccca cgacaacacg
    12301 tgttttagag ttatcactca tggtaagtct cccatctatt cgtttattca cgattgaagg
    12361 tcgtgtgtgc ttcacgattg aaggtcgctt gagcagtatt cattataaca cgcttggtta
    12421 gagaagacaa ggaagagctt aaaaattgtt ttttaaaact tatagtcaat atacagatta
    12481 tgtgaatgat gtgagtatac cttattctta tcttcattca aataactata ataaataaaa
    12541 caacccattt tctctaatct atttttcaag ttagagaaaa ggagtcgttt ttttaatgac
    12601 atttcctgaa atcataagat aggtacctaa agaatacgaa cataaatcta ttcaatcgaa
    12661 ccttatcttt gtttcaaaat taaaatgtca aatgttctta acatgattta atttaatcgg
    12721 cttaaaccca ttcaccattg gcattgactt tatagccatc tacagttgtg ttgactgcaa
    12781 gggcacctaa gcc
//
LOCUS       DAVLMQ010000048        12395 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000048 DAVLMQ010000000
VERSION     DAVLMQ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12395
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.048"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..700
                     /locus_tag="VXF95_001700"
                     /pseudo
     CDS             1..700
                     /locus_tag="VXF95_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            850..1104
                     /gene="blpM"
                     /locus_tag="VXF95_001701"
     CDS             850..1104
                     /gene="blpM"
                     /locus_tag="VXF95_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HEV1082211.1"
                     /translation="MDTKIMEQFHEMDITMLSSIEGGKNNWQTNVLEGGGAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVDLWAGVTGATGGF"
     gene            1120..1323
                     /gene="blpN"
                     /locus_tag="VXF95_001702"
     CDS             1120..1323
                     /gene="blpN"
                     /locus_tag="VXF95_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HEV1082212.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGRLLGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            1567..1716
                     /gene="blpO"
                     /locus_tag="VXF95_001703"
     CDS             1567..1716
                     /gene="blpO"
                     /locus_tag="VXF95_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HEV1082213.1"
                     /translation="MDTKMMSQFAVMDNEMLACVEGGDIDWGRKISCTAGVAYGAIDG
                     CATTV"
     gene            1820..1939
                     /locus_tag="VXF95_001704"
     CDS             1820..1939
                     /locus_tag="VXF95_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HEV1082214.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            2725..3108
                     /locus_tag="VXF95_001705"
     CDS             2725..3108
                     /locus_tag="VXF95_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HEV1082215.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVFYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            3160..3849
                     /locus_tag="VXF95_001706"
     CDS             3160..3849
                     /locus_tag="VXF95_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082216.1"
                     /translation="MKKYQLLFKTSAILSYLFFVFGLSQLTLIVQNYWQFSSQIGNLF
                     WIQNILSLLFIGVMIVVLVKTGHGYLFRIPRKKWLWYSILTVLVVVFQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYIALFFLVPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFVFATVGIIFAGLTRYTKSIYPSYAVHVINNIVATFP
                     FLLTFLHRVLG"
     gene            3891..4124
                     /locus_tag="VXF95_001707"
     CDS             3891..4124
                     /locus_tag="VXF95_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082217.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            4275..4886
                     /locus_tag="VXF95_001708"
     CDS             4275..4886
                     /locus_tag="VXF95_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082218.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGGFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMLYNSWPLLYYL"
     gene            5047..5841
                     /locus_tag="VXF95_001709"
     CDS             5047..5841
                     /locus_tag="VXF95_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HEV1082219.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            5838..6473
                     /gene="trmB"
                     /locus_tag="VXF95_001710"
     CDS             5838..6473
                     /gene="trmB"
                     /locus_tag="VXF95_001710"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HEV1082220.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEAGVSNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            6600..7079
                     /gene="rimP"
                     /locus_tag="VXF95_001711"
     CDS             6600..7079
                     /gene="rimP"
                     /locus_tag="VXF95_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HEV1082221.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            7123..8259
                     /gene="nusA"
                     /locus_tag="VXF95_001712"
     CDS             7123..8259
                     /gene="nusA"
                     /locus_tag="VXF95_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HEV1082222.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            8281..8574
                     /locus_tag="VXF95_001713"
     CDS             8281..8574
                     /locus_tag="VXF95_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HEV1082223.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            8567..8866
                     /locus_tag="VXF95_001714"
     CDS             8567..8866
                     /locus_tag="VXF95_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HEV1082224.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            8883..11675
                     /gene="infB"
                     /locus_tag="VXF95_001715"
     CDS             8883..11675
                     /gene="infB"
                     /locus_tag="VXF95_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HEV1082225.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDGYNDI
                     KMDDVIEAYVMEEIKR"
     gene            11926..12276
                     /gene="rbfA"
                     /locus_tag="VXF95_001716"
     CDS             11926..12276
                     /gene="rbfA"
                     /locus_tag="VXF95_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HEV1082226.1"
                     /translation="MVNHFRIDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         3838 a         2167 c         2793 g         3597 t
ORIGIN      
        1 atcaacttaa acacgcaaaa ggtggacgaa aacctaaatt aagcctagaa gaccttctta
       61 tggccactct tcaatatgtg tgagaatacc gcacttatga agaaattgcg gctgatcttg
      121 gtattcacga aagcaactta atccgtcgga gccaatgggt tgaagtaact cttgttcaaa
      181 gtggtgttac gatttcaaaa actcatctta gtgctgagga tacggtgatt gtggatgcaa
      241 cagaggtaaa aataaatcgt cctaaaaaaa tcaactagcc aattattctg gtaaaaagaa
      301 atttcacgct atgaaggctc aagcgattgt cacaagtcaa gggagaattg tttctttgga
      361 tatcactgtg aactattgcc acgatatgaa gttgttcaaa atgagtcgca gaaatatcgg
      421 acaaactggt aaaaccttgg ctgacagtaa ttatcaaggg ctcatgaaga tatatcctca
      481 agcacaaact ccacgtaaat ccagcaaact caaaccgcta acagttaaag ataaagccta
      541 taaccatgcg ttatctaagg agagaagcaa ggttgagagc atccttgcca aagtaaaaac
      601 gtttaaaatg ttttcaacaa cctatcgaaa tcatcgtaaa cgcttcggat tacgaatgaa
      661 tttgattgct ggcattatca atcatgaact aggattctag ttttgcagga agtctaatgt
      721 aatttttgca attcaagacg tttcgatgac tattcaagat ctggatgaaa aattttaaaa
      781 aacgatgata tactaaactt gtcaaagtta caacaagaca aaaattaaaa ataaaaaaga
      841 gtatttgtca tggatacaaa aattatggaa caatttcatg aaatggatat aactatgtta
      901 tctagtattg aaggaggcaa gaataattgg caaactaatg tcttagaagg tggtggtgct
      961 gcttttggtg gctgggggct agggacagct atttgtgctg cgagtggtgt tggagcacca
     1021 tttatgggag catgtggata cataggagct aaatttggtg tggatctttg ggcaggagta
     1081 acaggggcaa cgggtggatt ttaataaaag gagacttgta tgaatactta ttgtaatata
     1141 aatgaaacaa tgctgagtga ggtttatgga ggtaattccg gaggagcagc tgtagttgct
     1201 gctttaggtt gtgcagcggg tggagtgaaa tatgggagac ttctaggacc atggggcgct
     1261 gcaataggag gaattggagg agcagtggtt tgtggatatt tagcctatac cgctacatca
     1321 taaaaatgaa agctaaattt tatgaaggct atattcttta ttattctctt cgcttttcaa
     1381 acctatctta tttatctatc cataagtatc tccgataaaa aacaaaagac tattgaatta
     1441 acatcattga attgttttgt catattattt ctaatctatg ataaattaat ttttctcttt
     1501 attgcctatg tttttttgat aatttttata ttaaacttgt tccgtaactg aaaagtgata
     1561 tactatatgg atacaaaaat gatgtcacaa tttgcagtta tggataatga aatgcttgct
     1621 tgcgttgaag gtggagatat tgattgggga agaaaaatta gttgtacagc aggggttgca
     1681 tatggcgcaa ttgatgggtg tgcaacaacg gtttgacatt tctattggga ccatttgcta
     1741 taggaatagg tgtaactggt gctgcaggtg gagctatact tggaggtgta gcctatgcag
     1801 caatatgttg gtggtaatta tggattttaa aagttttatt attggtttag tagttggtat
     1861 atttggtcct tatatggatg acttaattag aaaaatattt tcaaaatctt ccaaaaagga
     1921 tacggatagt actctctaaa aaataaattt ctcccctgta tttgctagct taatttacag
     1981 gggagtttct ttaatattgt ttcgcctgtc aaaatgatat gtgatagcag gatgaaaagt
     2041 ctacaaacaa gttggtatca atacaatata aagaggaaag tatgttttta atgcttactt
     2101 tttaaatttt ttaacaattc aagatgtttc gatgacaatt caagatttgg atgaaaaatt
     2161 ttaaaaaaca atgatatact aaacttgtca aagttgcaac gggtgctgct acattatgtt
     2221 aaaaatcgct cttgattgat aagctggatt tgttaggaaa ggagtaaata attatggata
     2281 agaaaaagat agtttcgact ataatatgta tagtatttct tgtagtgtca gtagataatt
     2341 tttttagaga cttaaccccg ttactgttca ttttaaatat tattggcctg tcttgctttt
     2401 cagtgctaac atacattaac ataaaagaga tactcttaaa tataagtaaa tgatgatttg
     2461 gttagtccta gaaccaatca acttatgttt atcggcttgg cagattttat gtttgtcatt
     2521 tgtttgtata gaggtatttc agaaacagaa ttctatcaac aactaatcgc ttatataggt
     2581 gtattctctg cttgtttatc acgcttctgc tcatgtgggg cttgaagtat tataaaaagt
     2641 agctttctat ccttttctga caggatattt gagtagaagg ctctattaaa ttgttagtga
     2701 aataaatgaa tggaggtatt taatatgaaa tacagattat tttttgttat tttcttgagt
     2761 agtgtgttgg atattctttt agggacattt ttacaaatct ctatcgtatc tattgggtgg
     2821 cttgtttttt acagtggttt gtttgaagca ggagttttcc ttcttgctaa taaaggggtg
     2881 gcggtaaaaa tcaaggaagt agatattcga aatcgcttta aatttatttt tggaaaaacc
     2941 ttatggtttc aaattctttt gctcatcttt ttgataatca aactttatct tggtttggat
     3001 gcgaggttga ttttattcta tggacatatt ttcattgtct ttaatgcctt aatgtatcta
     3061 ttatctagta gtcaggttag ccttaaaaaa aacaaactgt cttcttaatc ttacagcagt
     3121 agagcctgac aaggtgaggt catagtaggg aggatttcta tgaaaaagta tcagcttcta
     3181 ttcaaaacaa gtgcaatttt atcctaccta tttttcgtat ttggtctttc tcagctgacg
     3241 cttatcgtcc aaaactattg gcaattttct tctcagatag gcaatttatt ctggattcaa
     3301 aatatcttga gtttactttt tattggagtc atgattgtgg ttcttgttaa gacaggccat
     3361 ggttatctct tccgcattcc aagaaaaaaa tggctttggt attcgatttt gacagtatta
     3421 gtggtagtgt tccagatctc ttttaacgtt cagacagcta aacatgttca gtcaactgcg
     3481 gaaggttggg ctgtattgat tggttatagt gggactaact ttgcagagct aggtatttat
     3541 atagccctgt tctttctggt tccactgatg gaagaattga tttatagagg actactgcaa
     3601 catgctttct ttaagcattc gcgatttggt cttgatttgc ttcttccttc tattttattt
     3661 gctctccctc atttttcaag cctgcctagt ctgttagata tcttcgtctt tgcaacagtt
     3721 ggaatcatct ttgctggttt gacccgctat accaagagca tttatccatc ctatgcggtg
     3781 catgtgatca ataatattgt agcgaccttc ccgtttttgc tcacttttct acatagggtc
     3841 ttggggtaaa aaaacaaaag gcttgctttt cagccataga ggaggtcatc atgtataaac
     3901 acttattttt cctagattcc aaaactttag atcggttgac accctatatt ctagtcttgg
     3961 cttctgacac cattgctttt aatgtttttg tgctaacctt tgtatctgcg gtggttttta
     4021 atttcctaaa ttccatgcta gctttaatgg ctatattcat aggggctggc tatgtggtcg
     4081 gattttggtt actaatactc aatgaaaatc aaagagcaaa ctaggaaact agccgcaggc
     4141 tgtacttgag tacggcaagg cgacgttgac gtggtttgaa tttgattttc gaagagtata
     4201 aaatggtttg ttttggaaag gctagaacta aagaatgacg tgtaggaagt ctgtttgttg
     4261 aggaggataa ttttatggag ttttttgata aatttcatgc cttgtgtttt ggatttttag
     4321 tactaataat tgtcattaca gttccttata cgattaacca tgggggtttt tttcaaaatg
     4381 aatctgcatt gattcttgta agtcttcttg taacctcgct gagtgttgct tatgctagaa
     4441 agtttgaaat gatttctttt gggatgttaa gcaagaaaca acttttgctt ttcattgcaa
     4501 tctttcttct aagtgtactt gagacgctgg tttatattca tttcttcgct gtttcttctg
     4561 gctcaggggt ccaacacttg gcggaagtca gcagaggaat ttccctgtct ttgattttaa
     4621 ctacctcagt ttttggtccc atccaggagg aactcatttt cagaggactt cttcaaggtg
     4681 cggtttttga caattcttgg ttagggcttg tgctaacttc ctctctcttt tctttcatgc
     4741 atggaccttc taatgtccct tcgtttattt tttatctact tgggggtttg ttgctgggct
     4801 ttgcttataa aaagagtcaa aacctatggg tttctactct agtccatatg ctttacaaca
     4861 gttggccact cttatattat ttataaaaat tatgaaaagg taagcagaag acggtgctta
     4921 cctttttcaa gctataatga tacccaagcc aatccagagg cttttctttg agaatcgggt
     4981 tagagtggtt gacgaatagg ccaaaaacta gtagaatagt aaggaaactt tatacggagg
     5041 aaagaaatgg atttgggtga taatgagcta acactgactc ccatacctgg gaaaagtggc
     5101 aaggcttata tgggtagcta tcctgatggg aagcgcatct ttgtaaaaat gaacacctct
     5161 ccaatcctac ctggtctagc tagagaacaa attgctccac aattattatg gagtcgtcgt
     5221 ttggcagatg ggcgtgatat gtgtgctcaa gaatggttga caggcaagat attgaccccc
     5281 tatgatatga atcgtaagca aatcgtcaat attttaaccc gtcttcatcg ctcacgtccg
     5341 ttgatgacac aattgagtcg tttgggctat gccatggaaa cacctgtaga tttactacag
     5401 tcttggcagg aaacggctcc agatgctttg cgtaaaaatc attttatcag tgaagtgatg
     5461 gctgatttac gtcagactat tccaggattt agagaggacc atgcgaccat tgtccatgga
     5521 gatgtacgac atagtaattg gattgagaca gatagtggct tgatttattt agtagattgg
     5581 gattcggttc gcttgaccga tcgcatgttt gatgtggccc atatgctctg ccattatatt
     5641 tcagaacatc agtggaagga atggttgacc tactacggtt acaagtacaa tcaaacggta
     5701 ttaagtaaat tgtattggta tggtcaattg tcttatttga gtcagatttc caagtattat
     5761 atgaaccaag atttagaaaa tgtcaatcgg gagattcatg gtttgcgtca tttccgagac
     5821 aagtatggaa agagaagatg agagttagaa atcgtaaagg ggcaacagaa ttactagagg
     5881 caaatcccca gtatgtggtc ctcaatccct tggaagccaa ggcaaaatgg cgggacttgt
     5941 ttggcaatga taatcccatt catgtggaag ttggaagtgg aaagggtgcc tttgtttcag
     6001 gtatggccaa gcaaaaccct gacatcaact atatcgggat tgatattcaa aagtctgttt
     6061 tgagctacgc tttggacaag gtgcttgaag ctggagtgtc taacatcaag ctcttgtggg
     6121 tagatggttc tgacttgact gactattttg aagacggtga gattgatcgc ttgtatctga
     6181 acttttcaga tccttggcct aaaaaacgcc atgaaaagcg tcgtttgact tacaagacct
     6241 tcttggatac cttcaagcgt atcttgcctg aaaatggaga aattcatttc aagacggata
     6301 accgtggctt gtttgagtat agcctagtga gcttttctca atatggcatg aaactcaatg
     6361 gtgtctggct agatttgcat gccagtgatt ttgaaggcaa tgtcatgaca gaatacgagc
     6421 aaaaattctc caacaagggg caagttatct accgagttga ggcagaattt taagaaatag
     6481 cctgaaatca ggctgtataa gtgcttttgc tttacataag ttagcaaatg tgctatacta
     6541 agggtaagaa tatgagaaag agaggcgggg aaatatcttc gcctcttgct tatgaggagg
     6601 tggacgcaat cgcaacaatc gtagaattag tcagagaagt tgtagaacct gtcatagaag
     6661 ctcctttcga actcgtggat atcgagtatg gaaagattgg cagtgacatg attctcagta
     6721 tttttgtaga taaacctgaa ggaattacct tgaacgacac ggcagacttg acagaaatga
     6781 tcagtcctgt cctagacacc atcaagccag atcccttccc agaacaatat ttcctagaaa
     6841 ttaccagtcc aggcttggaa cgtcctttga aaaccaagga tgccgtcgct ggagcggttg
     6901 ggaaatacat ccatgtcggg ctctaccaag ccatcgataa gcaaaaggtc tttgaaggaa
     6961 ccttgttggc cttcgaagag gacgagttga ctatggaata tatggacaag acacgtaaga
     7021 aaactgtcca aattccatat agtttagtat caaaagcacg tttagcagtt aaattataga
     7081 aaaagaaagg atagcttttg aggattcaaa agtgaagaaa acatgagtaa agaaatgcta
     7141 gaggccttcc gcattttgga agaagacaag ggaatcaaaa aagaagacat catcgacgca
     7201 gtagtagagt cgcttcgttc cgcttatcgc agacgctatg gtcagtcaga cagcgtagct
     7261 attgacttca acgaaaaaac aggtgacttt acagtttata ctgtccgtga agttgttgat
     7321 gaagtatttg atagccgttt ggaaatcagc ttgaaagatg ctcttgccat taattcagct
     7381 tatgaacttg gagacaaaat caagtttgaa gaagcaccag ctgagtttgg tcgtgtagca
     7441 gcccaatctg ccaaacaaac catcatggaa aaaatgcgca agcaaacacg tgccatcact
     7501 tacaatactt acaaagaaca tgagcaagaa atcatgtctg gtacagtaga acgctttgac
     7561 aaccgcttta tctatgtcaa ccttggtagc atcgaagccc aattgtcaaa acaagaccaa
     7621 attcctggag aagtttttgc ttctcatgat cgtatcgaag tttatgttta caaggttgaa
     7681 gacaaccctc gtggtgtgaa cgtctttgtt agccgtagcc atccagaaat gatcaaacgt
     7741 ttgatggagc aagaaattcc agaagtttat gatggaactg ttgaaatcat gagcgtggct
     7801 cgtgaagcag gtgaccgtac gaaggttgct gttcgtagcc acaatccaaa cgtggatgct
     7861 atcggtacaa tcgttggacg tggtggtgct aatatcaaga agattactag caaattccac
     7921 ccagctcgtt acgatgctaa aaatgatcgc atggtaccaa tcgaagaaaa tatcgatgtt
     7981 atcgagtggg tagcagatcc agctgaattt atctacaatg ccatcgctcc tgctgaggtt
     8041 gaccaagtta tctttgatga aaacgacagc aaacgtgcct tggtggttgt tccagataac
     8101 aagctttctc ttgccattgg tcgtcgtgga caaaacgtgc gcttggcggc tcacttgact
     8161 ggttaccgta tcgatatcaa gtctgctagc gaatttgaag ccatggaaga cgctgcttca
     8221 gtagagttgg aagtagaaaa cgatactgta gaagaataaa agctgctaga ggagggaaag
     8281 atgaaaacaa gaaaaatccc tttgcgcaag tctgttgtgt ctaacgaagt gattgataag
     8341 cgtgatttgc tccgcattgt caagaacaag gaaggacaag tctttattga tcctacgggc
     8401 aaggccaatg gccgcggcgc ttatatcaaa ctagacaatg cagaagccct agaggcgaaa
     8461 aagaagaagg tctttaaccg cagttttagc atggaagtgg aagaaagctt ttatgacgag
     8521 ttgatcgctt atgtggatca caaagtgaaa agaagagagt tgggacttga ataagcaaaa
     8581 gataagtaat ctcttggggc ttgctcagcg agcagggcgc atcatatcgg gtgaagaatt
     8641 ggtggtcaag gccattcaag acggcaaggc caagttggtc tttctagctc atgatgctgg
     8701 acccaatctg accaagaaga ttcaagataa aagtcattat tatcaagtag aaattgtaac
     8761 cgtgttttca acactggaat taagcatagc agtcgggaaa tcgagaaagg ttttggctgt
     8821 aacagatgct ggatttacaa agaaaatgag gtctcttatg gaatagaaga ggaggacatg
     8881 atttgtctaa gaaaagattg tacgaaatcg caaaagaact tggaaaagaa agtaaagaag
     8941 ttgtagcgcg tgcaaaagag ttgggcttgg atgtgaaaag ccactcatca agtgtggaag
     9001 aagctgtcgc tgcaaaaatt gctgccagct ttaagcctgc agctgctccg aaagtagaag
     9061 caaaacctgc agcaccaaaa gtaagtgcag aaaagaaagc cgaaaaatct gagccagcta
     9121 aaccagctgt agctaaggaa gaggcaaaac cggctgagcc agttgctccg aaaacagaaa
     9181 aagtagcagc gaaaccgcaa agccgtaatt tcaaggctga gcgtgaagcc cgtgctaaag
     9241 agcaggcaga acgacgcaag caaaataagg gcaataaccg tgaccaacaa caaaacggaa
     9301 accgtcagaa aaacgacggc cgtaatggtg gaaaacaagg tcaaagcaac cgcgacaatc
     9361 gtcgctttaa tgaccaagct aagaagcagc aaggtcagca aaaacgtaga aatgagcgcc
     9421 gtcagcaaga ggacaaacgt tcaaatcaag tggctccacg tattgacttt aaagcccgtg
     9481 cagcagccct aaaagcagag caaaatgcag agtacgctcg ttcaagtgag gaacgcttca
     9541 agcagtatca ggctgctaaa gaagccttgg ctcaagctaa caaacgcaag gaaccagagg
     9601 aaatctttga agaagcggct aagttagctg aacaagcaca gcaagttcaa gcagtggttg
     9661 aagtcgtccc tgagaaaaaa gaacctgcag tggatacacg tcgtaaaaaa caagctcgac
     9721 cagacaaaaa tcgtgacgat tatgatcatg aagaagatgg tcctagaaaa caacaaaaga
     9781 atcgaagtag tcaaaatcaa gtgagaaatc aaaagaatag taactggaat aacaacaaaa
     9841 agaacaaaaa aggcaataac aagaacaacc gtaatcagac tccaaaacct gttacggagc
     9901 gtaaattcca tgaattgcca acagaatttg aatatacaga tggtatgacc gttgcggaaa
     9961 tcgcaaaacg tatcaaacgt gaaccagctg aaatcgttaa gaaacttttc atgatgggtg
    10021 tcatggccac acaaaaccaa tccttagatg gggaaacaat tgaactcctc atggtggatt
    10081 acggtatcga agccaaacaa aaggttgaag tggataatgc tgacatcgaa cgtttctttg
    10141 tcgaagatgg ttatctcaat gaagatgaat tggttgagcg tccaccagtt gttactatca
    10201 tgggacatgt tgaccacggt aaaacaaccc ttttggatac tcttcgtaac tcacgtgttg
    10261 cgacaggtga agcaggtggt attactcagc atatcggtgc ctaccaaatc gtggaaaatg
    10321 gtaagaagat taccttcctt gatacaccag gacacgcggc ctttacatca atgcgtgcgc
    10381 gtggtgcttc tgttaccgat attacgatct tggtcgtagc ggcagatgac ggggttatgc
    10441 ctcagactat tgaagccatc aaccactcaa aagcagctaa cgttccaatc atcgtagcca
    10501 ttaacaagat tgataaacca ggtgctaacc cagaacgcgt tatcggtgaa ttggcagagc
    10561 atggtgtgat gtcaaccgct tggggtggag attctgaatt tgttgaaatc tcggctaaat
    10621 tcaaccaaaa tatcgaagaa ttgttggaaa cagtccttct tgtggctgaa atccaagaac
    10681 tcaaggcaga cccaacagtt cgtgcgatcg gtacggttat cgaagcgcgc ttggataaag
    10741 gaaaaggtgc ggtcgcaacc cttcttgtac aacaaggtac cttgaatgtt caagacccaa
    10801 tcgttgtcgg aaataccttc ggtcgtgtcc gtgctatgac caacgacctt ggtcgtcgtg
    10861 ttaaagttgc tggaccatca acaccagtct ctatcacagg tttgaacgaa gcaccgatgg
    10921 cgggtgacca ctttgccgtt tacgaggatg aaaaatctgc gcgtgcagca ggtgaagaac
    10981 gtgccaaacg tgccctcatg aaacaacgtc aagctaccca acgtgttagc cttgaaaacc
    11041 tctttgatac ccttaaagct ggggaactca aatctgttaa tgttatcatc aaggctgatg
    11101 tacaaggttc tgttgaagcc ctttctgcct cacttcaaaa gattgacgtg gaaggtgtca
    11161 aagtgactat cgtccactca gcggtcggtg ctatcaacga atcagacgtg acccttgccg
    11221 aagcttcaaa tgcctttatc gttggtttca acgtacgccc tacaccacaa gctcgtcaac
    11281 aagcagaagc tgacgatgtg gaaatccgtc ttcacagcat tatctacaag gttatcgaag
    11341 agatggaaga agctatgaaa gggatgcttg atccagaatt tgaagaaaaa gttattggtg
    11401 aagcggttat ccgtgaaacc ttcaaggtgt ctaaagtggg aactatcggt ggatttatgg
    11461 ttatcaacgg taaggttgcc cgtgactcta aagtccgtgt tatccgtgat ggtgtcgtta
    11521 tctatgatgg tgaactcgca agcttgaaac actataaaga cgacgttaag gaagttacaa
    11581 acggccgtga aggtggattg atgatcgacg gctacaatga tattaagatg gatgatgtga
    11641 ttgaggcgta tgtcatggaa gaaatcaaga gataagattt tttgctcctt tcttaggtgg
    11701 tgagggacgc aagcaaaccg atggtttcat tgcttatttt tgagcctagg gtctcaaaaa
    11761 tcccctgtga tgggactgat aaatcagttc catcactttc accacggcga aagaagcaga
    11821 tgacttcaaa ttgaacttcg tttcaattta aactgaaaat caagaagttt aaaatagcta
    11881 ggtctgctgg cctagctttt ggttcaaagt agagaaagga atatcatggt aaatcatttc
    11941 cgtatagatc gtgtgggcat ggaaatcaag cgtgaagtca atgagatttt gcaaaagaaa
    12001 gtccgtgatc cacgtgtcca aggtgtgacc atcacagatg ttcagatgct gggtgacttg
    12061 tctgttgcca aggtttatta caccattttg agtaaccttg cttcggataa ccaaaaagcc
    12121 caaatcgggc ttgaaaaagc aactggtacc atcaaacgtg aacttggtcg caatttgaaa
    12181 ttgtacaaaa tcccagattt gaccttcgtc aaagacgagt ccatcgagta tggaaacaag
    12241 attgacgaga tgctacgcaa tctggataag aactaaagaa gaggggttgc ccctcttttt
    12301 tggtggagga aaataggttg aatttgaaat ggaaaaatat tcttttataa tagattgaaa
    12361 ctagaatagt acgcctctac ttctaaaaca ttgtt
//
LOCUS       DAVLMQ010000049        12363 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000049 DAVLMQ010000000
VERSION     DAVLMQ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.049"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            95..904
                     /locus_tag="VXF95_001717"
     CDS             95..904
                     /locus_tag="VXF95_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000926538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HEV1082227.1"
                     /translation="MLLQKELIPMIEANLPNMAYAEKDIAKFFLKQQPLNDYSSKALC
                     EYLNVSKATLTRFAKKCGFKGFRQFIFKYQEMIHEKEKLALYTEATEKVLSDYEEMLR
                     KTYTVLDEVQLERIAEMIETAERVYLYGKGSSVLALQEMKMRFMRLGVIGEVLSDEDM
                     ILWSSLLLNENCLVIGASISGQTDIVLEGLQKAADKGAKTVLMTTRKFDEEDCFFDEL
                     LLLASTDHLSYGNRISPQFPILLITDCLFSNYLESPERQYYYNQTIIHKEE"
     gene            909..1610
                     /locus_tag="VXF95_001718"
     CDS             909..1610
                     /locus_tag="VXF95_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1082228.1"
                     /translation="MSQIWTKEKFISQVQGGVIVSCQALPGEALYNEEFSLMPFMAKA
                     ALEAGAVGIRANSVRDIKAIQKVVDLPIIGIIKRDYPPQEPYITATMKEVDELVECGT
                     TVIAFDATLRPRYDGLVVSEFIKKIKEKYPNQLLMADVSNLDEGLYAFKSGVDFVGTT
                     LSGYTSTSVQSDEPDFELMKKLADFNIPVIAEGKIHYPEQLKKAYSLGVTSVVIGGAI
                     TRPKEIAQRFINVIK"
     gene            1635..2552
                     /locus_tag="VXF95_001719"
     CDS             1635..2552
                     /locus_tag="VXF95_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HEV1082229.1"
                     /translation="MKDLTKYKGVIPAFYACYDENGEISQDRVKSLVQYFIDKGVKGI
                     YVNGSSGECIYQSVEDRKQIIEAVMEVAKGKLTVINHIACNNTKDSIELAKHSESVGV
                     DAIAAIPPIYFKLPEYSIAAYWNAMSEAASNTDFIIYNIPQLAGVALTGSLYATMRQN
                     PRVIGVKNSSMPVQDIQMFVAAGGEDYIVFNGPDEQYLGGRLMGAEAGIGGTYGVMPD
                     LFLKLESLIQERDLDTAKKLQYAINEVIYKMISGKANMYAVAKEVLRLNEKLDLGSVR
                     QPLEALAEGDLEVAKQAAELIQQARKEFL"
     gene            2580..4121
                     /locus_tag="VXF95_001720"
     CDS             2580..4121
                     /locus_tag="VXF95_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:solute symporter"
                     /protein_id="HEV1082230.1"
                     /translation="MGTTGFTIIDLIILIVYLLAVLVAGIYFSKKEMKGKEFFKGDGS
                     VPWYVTSVSIFATMLSPISFLGLAGSSYAGSWILWFAQLGMVVAIPLTIRFILPIFAR
                     IDIDTAYDYLDKRFNSKALRIISALLFIIYQLGRMSIIMYLPSAGLSVLTGIDINILI
                     ILMGVVAIVYSYTGGLKSVLWTDFIQGVILISGVVLALFVLIANIKGGFGAVAETLAN
                     GKFLAANEKLFDPNLLSNSIFLIVMGSGFTILSSYASSQDLVQRFTTTQNIKKLNKML
                     FTNGVLSLATATVFYLIGTGLYVFYQVQNADSAASNIPQDQIFMYFIAYQLPVGITGL
                     ILAAIYAASQSTISTGLNSVATSWTLDIQDVISKNMSDNRRTKIAQFVSLAVGLFSIG
                     VSIVMAHSDIKSAYEWFNSFMGLVLGLLGGVFILGFVSKKANKQGAYAALIVSTIVMV
                     FIKYFLPPTAVSYWAYSLISISVSVVSGYIVSVLTGNKVSAPKYTTIHDITEIKADSS
                     WEVRH"
     gene            4140..4598
                     /locus_tag="VXF95_001721"
     CDS             4140..4598
                     /locus_tag="VXF95_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1082231.1"
                     /translation="MIISEQSDFKRYASVNKYFSKVCDFLENTNLTDLVDGKIDIDGE
                     NVFANCMTYLADGVPGDIFETHKKYLDIHIVVENTEKMAVTSPVRAQSRVPFSEEKDI
                     AFYDSKDYQIVELLPGNMLVTFEEDLHQPKIHCNDETVKKLVIKVLNEEK"
     gene            4600..6822
                     /locus_tag="VXF95_001722"
     CDS             4600..6822
                     /locus_tag="VXF95_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exo-alpha-sialidase"
                     /protein_id="HEV1082232.1"
                     /translation="MKKNIKQYVTLGTVVVLSAFVANSVAAQETETSEVSTPKLVQPV
                     APTTPISEVQPTSDNSSEVTVQPRTVETTVKDPSSTAEETPVLEKNNVTLTGGGENVT
                     KELKDKFTSGDFTVVIKYNQSSEKGLQALFGISNSKPGQQNSYVDVFLRDNGELGMEA
                     RDTSSNKNNLVSRPASVWGKYKQEAVTNTVAVVADSVKKTYSLYANGTKVVEKKVDNF
                     LNIKDIKGIDYYMLGGVKRAGKTAFGFNGTLENIKFFNSALDEETVKKMTTNAVTGHL
                     IYTANDTTGSNYFRIPVLYTFSNGRVFSSIDARYGGTHDFLNKINIATSYSDDNGKTW
                     TKPKLTLAFDDFAPVPLEWPREVGGRDLQISGGATYIDSVIVEKKNKQVLMFADVMPA
                     GVSFREATRKDSGYKQIDGNYYLKLRKQGDTDYNYTIRENGTVYDDRTNRPTEFSVDK
                     NFGIKQNGNYLTVEQYSVSFENNKKTEYRNGTKVHMNIFYKDALFKVVPTNYIAYISS
                     NDHGESWSAPTLLPPIMGLNRNAPYLGPGRGIIESSTGRILIPSYTGKESAFIYSDDN
                     GASWKVKVVPLPSSWSAEAQFVELSPGVIQAYMRTNNGKIAYLTSKDAGTTWSAPEYL
                     KFVSNPSYGTQLSIINYSQLIDGKKAVILSTPNSTNGRKHGQIWIGLINDDNTIDWRY
                     HHDVDYSNYGYSYSTLTELPNHEIGLMFEKFDSWSRNELHMKNVVPYITFKIEDLKKN
                     "
     gene            6862..7971
                     /locus_tag="VXF95_001723"
     CDS             6862..7971
                     /locus_tag="VXF95_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HEV1082233.1"
                     /translation="MVNYGIVGAGYFGADLARSMNKIEDAKVVAVFDPNHGEEVAQEL
                     GSDVCASLDELVAREDIDCVIVASPSYLHREPVVKAAQHGKHVFCEKPIALSYEDCKA
                     MVDACKENNVIFMAGHIMNFFNGVHHAKELITQGKIGKVLYCHAARTGWEEQQPTVSW
                     KKLRSQSGGHLYHHIHELDCIQFIMGGLPEKATMVGGNVYHKGENFGDEDDMLIVNLE
                     YSDDRYAVLEYGNAFRWGEHYVLIQGTEGAIKLDLFNTGGTLRVKGEGESHFLVHETQ
                     EEDDDRTAIYTGRGMDGAIAYGKPGVRCPLWLQTCIDKEMEYLHDIIKGGEITEEFEK
                     LLNGVAALESIATADACTLSVKEDRKVSLSEITNA"
     gene            8128..9018
                     /locus_tag="VXF95_001724"
     CDS             8128..9018
                     /locus_tag="VXF95_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HEV1082234.1"
                     /translation="MKIIGIDIGGTTIKADLYDEFGTSLNHFKEIETIIDYDLGTNQI
                     LNQVCDLIGEYTLNHSIDGVGISTAGVVNANTGEIIYAGYTIPGYIGVNFTAEIEKRF
                     GLYTFVENDVNCAALGELWKGQAKDKKNVVMVTIGTGIGGSIIVNGQIVNGFNYTAGE
                     VGYIPVGNSDWQSKASTTALIHLYQKKSLKTNQTGRTFFTDLRSGDKVAEETFEIFVE
                     NLTKGLLTISYLLNPEILILGGGILDSKDILLPEIQSSLAKNAMDNRFLPKNLVAATL
                     GNEAGRIGAVKNFLDRISNK"
     gene            9043..9366
                     /locus_tag="VXF95_001725"
     CDS             9043..9366
                     /locus_tag="VXF95_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082235.1"
                     /translation="MTNSVFSTMQDIENVATDIIKSYDNEIYTYKAVSQEELEKLEKS
                     YDEKSHEELVSIESNLEMKQQNLIDEVNKTIKENDANIQYISSSRRGEFVEKIIGRVV
                     EKYGH"
     gene            9356..11347
                     /locus_tag="VXF95_001726"
     CDS             9356..11347
                     /locus_tag="VXF95_001726"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HEV1082236.1"
                     /translation="MAISQMKRISLLFSKSSLDDVLKTIQELESVQFRDLKVQDNWSE
                     ALEKDEVVFPTIQIFHTSNSNHGVIEGNDALTYLMNQQQHLEATVEKLQEYLPKENTF
                     KLLQQPPITTSYEELEKFGKANVAEGVLKKVNHQINRVHELERHIQSNNEEIERLIKW
                     EKLEIVPANLEQFSFCKGKVGTIPRTEDNRLYNSLLENNIEVQEIFSNDREYGVVVFY
                     QSSYSIDFDEYLFEPFDYSRKELPKQRVVDLDQENMQLITEKENIIASLQDSKKYLID
                     LQWQIDYILSIYARQISKNNFLCTPHLVALEGWIEETRILYFIKVMDEHFGHSIYIYE
                     SETLTDNQDEIPIKLTNHSLIEPFELLTEMYALPKYYEKDPTPVLAPFYFTFFGMMVA
                     DLGYGLLLFLGTMLALKIFHLPSATKRFLKFFNILGVAVAIWGGIYGSFFGYELPFHL
                     ISTTSDVMTILVVSVVFGFITVFAGLLASGLQKVRMKKYAEAYNSGFAWCVILLGLLF
                     IAVGMLMPDMRPLFVLGKWVSIFNAVGILIVSIIQTKSLSGIGAGLFNLYNISSYIGD
                     LVSFTRLMALGLSGASIASAFNLIVGLFPGILAKLTIGLVLFILLHAINIFLSLLSGY
                     VHGARLIFVEFFGKFYEGGGKPFQPLKASEKYIKVITKN"
     gene            11363..11839
                     /locus_tag="VXF95_001727"
     CDS             11363..11839
                     /locus_tag="VXF95_001727"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HEV1082237.1"
                     /translation="MEHLATYFSTYGGAFFAALGIVLAVGLSGMGSAYGVGKAGQSAA
                     ALLKEQPEKFASALILQLLPGTQGLYGFVIGILIWLQLTPELPLEKGVAYFFVALPIA
                     IVGYFSAKHQGNVAVAGMQILAKRPKEFMKGAILAAMVETYAILAFVVSFILTLRV"
     gene            11873..>12363
                     /locus_tag="VXF95_001728"
     CDS             11873..>12363
                     /locus_tag="VXF95_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000067169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082238.1"
                     /translation="MSNLENLRESVIEQAHEKGRMKLLDSKKKIDDEFEMQKSLIIKK
                     KEAEHERKLKELQQKYQIIFQQLKNKERQSTLVSKQKILKELFQSALLEMESWSADKE
                     MEFIYRILERYSQQEVIVTFGERTLAKFNLEQLEKLKFSFPNYLFSEQPISNESGLLI
                     SIG"
BASE COUNT         4199 a         1772 c         2442 g         3950 t
ORIGIN      
        1 ttggaaacta gtttctaatt tatgaaaaat attgaaaaaa aaaaaaagtg ttaaaataaa
       61 gaatgtaaac gtttacttca actaaggagc tcatatgtta ctgcaaaaag aactaattcc
      121 aatgatagaa gctaacttac caaatatggc atatgctgaa aaagacattg ctaaattctt
      181 cttaaaacag caacctctga atgattattc atctaaagca ttgtgcgaat accttaatgt
      241 atccaaagca acattgactc gatttgcgaa aaaatgtggt tttaaaggtt ttagacaatt
      301 cattttcaaa taccaagaga tgattcatga gaaagaaaag ttggcattat atacagaggc
      361 aacagaaaaa gttttatccg actatgagga aatgttgaga aaaacttaca cggttcttga
      421 tgaagttcaa cttgagcgta ttgctgagat gatagaaact gctgagcgtg tatatctcta
      481 cggtaaagga agttctgttc ttgctttaca agaaatgaag atgagattta tgcgtctcgg
      541 agtgattggt gaagtattat cagacgagga tatgattttg tggagtagct tactacttaa
      601 tgaaaattgc cttgtcattg gagcatccat ttcaggtcaa actgatattg tactagaagg
      661 tctacaaaaa gctgcagata aaggcgctaa aacagtttta atgactacaa gaaaatttga
      721 cgaagaagat tgtttctttg atgaactatt gttattagct tcgaccgatc atctctcgta
      781 tggcaatcgc atatcacctc agtttccaat acttttaatt acagactgct tattctctaa
      841 ttatctggaa agtccagaga gacaatatta ttacaatcaa actattatcc ataaggagga
      901 ataataaaat gagccaaatt tggactaaag aaaaatttat aagccaagtt caaggtggag
      961 tcattgtttc ttgtcaagct ttacctggtg aagcccttta taatgaagaa tttagcttga
     1021 tgccttttat ggctaaagca gctttagagg caggagcagt gggcattcgc gcaaattctg
     1081 tgcgtgatat taaagcaatt cagaaagtag tagatttacc aataattgga attatcaaaa
     1141 gggattatcc acctcaagaa ccatatatta ctgctacgat gaaagaagta gatgaacttg
     1201 tagaatgcgg aacaacagtc attgcatttg atgcaacttt aagaccaaga tatgatggct
     1261 tagttgtcag tgaatttatc aaaaaaataa aagaaaaata tccgaatcaa ttgctgatgg
     1321 cggatgtaag taatttagat gaaggtctct atgcatttaa atcaggcgtt gattttgttg
     1381 gtacaacatt atcaggttac acaagtacaa gtgtacaatc agatgagcct gattttgaac
     1441 taatgaaaaa attggctgat tttaatattc cggtaattgc cgaaggaaaa attcattatc
     1501 cagaacaatt aaaaaaagct tatagtttag gtgttaccag tgtagtcatt ggtggagcga
     1561 ttacacgtcc aaaagaaatt gctcagcgat ttattaatgt catcaaataa aaaacaatat
     1621 aaaggagaaa tctgatgaaa gatttaacta aatacaaagg cgttatccct gcattttatg
     1681 cttgctatga tgaaaatggt gaaattagcc aagatcgtgt aaaatctctg gtacaatatt
     1741 tcattgacaa aggtgtaaaa ggtatctatg taaatggttc ttcaggtgaa tgtatttacc
     1801 aaagtgtaga agatcgtaaa caaattattg aagctgttat ggaagttgct aaaggtaaat
     1861 taacagttat caaccatatt gcatgtaata acacgaaaga tagtatcgaa ttggcaaaac
     1921 attcagaaag tgttggagtc gatgctattg cagctatccc acctatttat ttcaaattgc
     1981 cagagtattc aatcgcagca tattggaatg caatgagtga agctgcgtca aatacagatt
     2041 ttattatcta taatattcca caattggcag gggttgcgtt gactggtagt ttgtatgcaa
     2101 caatgcgtca aaatcctcgt gtgattggag ttaaaaattc ttctatgcct gtacaagata
     2161 ttcaaatgtt tgtagctgca ggtggagaag attacattgt attcaatggt ccagatgaac
     2221 aatatcttgg tggtcgcttg atgggagcag aagctggtat tggtggtact tatggcgtta
     2281 tgccagattt gttcttgaaa ttggaaagtt tgattcaaga acgagattta gatacagcta
     2341 aaaaacttca atatgctatc aatgaagtta tctataagat gatatcaggt aaggcaaata
     2401 tgtatgctgt agcaaaagaa gttttgcgtc taaatgaaaa acttgattta ggttctgttc
     2461 gtcaaccttt agaagcattg gcagaaggtg acttggaagt tgcaaaacaa gcagcagaac
     2521 ttattcaaca agcacgaaaa gaatttttat aataaataaa atcaatatgg agatatgtta
     2581 tgggcacaac aggatttaca ataattgact taattatctt gattgtttat ttacttgcgg
     2641 tgttggttgc aggtatctat ttctctaaaa aagagatgaa aggaaaagag ttctttaaag
     2701 gagatggttc ggttccttgg tatgttactt cggtatccat ttttgccaca atgctcagtc
     2761 cgatttcctt cttgggactc gctggtagct cttatgcagg tagctggatt ttatggtttg
     2821 ctcaattagg gatggtagta gctattccac tgacaattcg ttttatctta cctatctttg
     2881 cacggataga catcgatacg gcatatgatt acttggataa acgttttaat tctaaagcac
     2941 ttcgtattat ttcagcactc ttgtttatta tttatcaatt gggacgtatg tctatcatta
     3001 tgtacctccc atcagctggt ttatcagtat tgacaggaat tgacatcaat attttgatta
     3061 ttttgatggg tgtagttgca attgtttatt cttatactgg tggtctaaaa tccgtattat
     3121 ggacagactt tattcaaggt gtgattctga ttagtggtgt cgttttagct ttatttgtac
     3181 tgattgctaa tattaaaggt ggctttggtg cagtagcaga aacattagca aacgggaaat
     3241 tccttgctgc aaatgaaaaa cttttcgatc ctaacttgct ttcaaactcc atctttttaa
     3301 ttgtgatggg ttcaggcttt acaatcttgt cttcctatgc ttcatctcaa gatttggttc
     3361 aacgttttac tacaacacaa aatattaaga aacttaataa gatgttgttc acaaacggtg
     3421 ttttgtcact tgcaactgca acagtctttt acttgattgg tacaggcttg tacgtattct
     3481 atcaagtaca aaatgcagat agtgcagcta gcaatatccc tcaagaccaa atctttatgt
     3541 actttattgc ataccagtta ccagtaggta tcacaggttt gatcttggca gcgatttatg
     3601 cagcatctca atcaactatt tcaacaggtt tgaactctgt tgcaacttca tggacattgg
     3661 atattcaaga tgtcatttct aaaaatatgt cagacaatcg tcgtacgaaa attgcacaat
     3721 tcgtatctct agcagtaggt ttattctcaa ttggtgtttc cattgtcatg gctcactcag
     3781 atattaaatc tgcatacgaa tggttcaata gtttcatggg acttgtactt ggtctacttg
     3841 gtggtgtatt tattcttgga tttgtttcta aaaaagcaaa taaacaaggt gcttatgcag
     3901 cgctgattgt atcaaccatc gtcatggtat ttattaaata cttccttcct ccaacagctg
     3961 ttagctactg ggcatattca ttgatttcaa tctctgtatc agtagtttca ggttatattg
     4021 tatctgttct tactggaaat aaagtatctg cacctaaata tacaacgatt catgatatta
     4081 cagaaattaa agcggattca agttgggaag ttcgtcacta atagaaaaga gaaaataata
     4141 tgattatttc tgaacaatct gattttaaac gatatgcttc tgtcaataaa tatttttcaa
     4201 aagtctgtga ttttttagaa aatacaaatt tgacagattt agttgatgga aaaattgata
     4261 ttgacgggga aaatgttttt gcaaattgta tgacttatct agctgatgga gttccaggag
     4321 atatttttga aactcataag aaatatttag atattcatat tgttgttgaa aatactgaaa
     4381 aaatggcagt aacttcccca gttcgtgccc agtcacgtgt accttttagc gaagagaagg
     4441 atattgcttt ttacgatagc aaagactatc aaattgttga attgcttcca gggaatatgt
     4501 tggtgacttt tgaagaagat cttcaccaac caaagattca ttgcaatgat gaaacggtta
     4561 aaaaacttgt tatcaaagtt ttaaacgagg aaaaataaaa tgaaaaaaaa tattaaacaa
     4621 tatgtaacct taggtactgt agtggtatta tcagcatttg ttgctaactc agttgcagct
     4681 caggagactg aaacttctga agtatcaaca ccaaagttgg tgcaacctgt tgcaccaacg
     4741 actccgattt cggaagtaca acctacatcg gataactctt cggaagttac tgtacaacct
     4801 cgaacagttg aaactactgt taaggatcca tcttctacag cggaagaaac tcctgtctta
     4861 gaaaaaaata atgttacttt aacagggggc ggagaaaatg ttactaaaga gttaaaggat
     4921 aaatttacta gcggtgactt tactgtagtg attaagtaca atcagtcaag tgagaaaggc
     4981 ttacaagctc tgtttggaat atctaattcc aaacccggtc aacaaaatag ttatgtagat
     5041 gtgttcctta gagacaatgg tgagttgggg atggaagcgc gtgatacttc ttccaataaa
     5101 aataacctag tatccagacc tgcttcagtt tggggtaagt acaaacaaga ggctgtgact
     5161 aacactgttg cagtagtagc agattcagtc aaaaaaacat attctttata cgcaaatggt
     5221 acaaaagtag tagaaaagaa agtggataat ttcctaaaca tcaaggatat taaaggtatt
     5281 gattactata tgcttggggg agtgaaacgt gcaggaaaaa cggcgtttgg ttttaacgga
     5341 acactagaaa atatcaaatt ctttaatagt gcattggatg aagaaactgt taaaaagatg
     5401 acaacaaacg ctgttactgg acatttaatt tatacggcta atgatacaac aggttctaac
     5461 tatttccgta ttccagttct gtatactttt agcaatggtc gggtattttc aagcattgac
     5521 gctcgttacg gtggaactca tgatttcttg aataaaatta atattgctac aagttatagt
     5581 gatgataatg gtaagacatg gactaaacca aaattaacat tggcattcga tgattttgcg
     5641 ccagtaccat tagaatggcc tcgtgaagtt ggtggacgtg acttacaaat cagcggtggt
     5701 gcaacctata ttgactctgt tattgttgaa aaaaagaaca aacaagtact catgtttgct
     5761 gatgtgatgc ctgctggagt aagttttaga gaagcaacta gaaaagattc aggttataaa
     5821 caaattgatg gtaattatta ccttaaatta aggaaacaag gtgatactga ttacaattat
     5881 actattcgtg agaatggtac tgtatacgac gatcgtacca acagaccaac tgaattttca
     5941 gtagataaaa atttcggtat taaacaaaat ggtaattatt tgacggtaga gcaatattcg
     6001 gtttcatttg aaaataataa aaagactgaa tatcgtaatg ggactaaagt ccatatgaat
     6061 atcttctaca aagatgcatt gtttaaagta gtgccaacga actatattgc atatatttct
     6121 agcaatgatc atggcgaatc ttggtctgca ccaactttat tacctcctat aatgggactt
     6181 aatcggaatg cgccatattt aggtcctgga cgtggaatca ttgaaagctc aactggacgt
     6241 attcttattc cgtcttacac tggtaaagag tctgcgttca tttatagtga cgataatgga
     6301 gcatcttgga aagttaaagt agtgccactt ccttctagtt ggtcagcaga agcacaattt
     6361 gtagaattga gtccaggagt aattcaagca tatatgcgta caaataatgg taaaattgca
     6421 tatttaacaa gtaaagacgc aggtactact tggagtgcac cggaatattt gaaatttgtt
     6481 tcaaatccaa gttatggaac acaattatca atcatcaatt atagccaatt gattgatggt
     6541 aaaaaggctg tcattttaag tactccaaac tccacaaatg gtcgtaaaca cggacaaatt
     6601 tggattggtc taattaatga tgataataca attgattggc gttatcatca cgacgttgat
     6661 tatagtaact atggatactc atattcaaca ttgacagagt taccaaatca tgaaattgga
     6721 ttgatgtttg aaaaatttga ttcatggtct cgtaatgaac ttcatatgaa aaatgttgta
     6781 ccatatataa catttaagat tgaagatctg aaaaagaatt aaagctgaaa tttgaaaata
     6841 tataaaaaga ggataaaaat tatggtaaat tacggtattg ttggagctgg atattttgga
     6901 gctgatttag ctcgctcaat gaacaaaatt gaagatgcaa aagtggttgc ggtatttgac
     6961 ccaaatcatg gagaagaagt tgctcaagag ttgggatcag atgtttgtgc aagtttagat
     7021 gaacttgtag cacgtgaaga tattgattgt gtgatcgtag cttcacctag ctaccttcac
     7081 cgtgaaccag ttgtgaaagc tgctcaacat ggcaaacacg tattttgtga aaagccaatt
     7141 gcattgtctt atgaagattg taaagccatg gttgacgcat gtaaagaaaa taatgtcatc
     7201 tttatggctg gtcacatcat gaacttcttt aacggtgtac accatgctaa agaattgatt
     7261 actcaaggta aaatcggtaa agttctttat tgccatgctg ctcgtacagg ttgggaagaa
     7321 caacaaccaa ctgtatcatg gaagaaactt cgttctcaat ctggaggaca tttgtaccac
     7381 catattcatg aattagattg cattcagttt atcatgggag gacttcctga aaaagcgaca
     7441 atggtaggag gcaatgtata tcataaaggt gaaaactttg gtgatgaaga tgatatgctc
     7501 attgtaaact tagaatactc tgatgatcgt tatgctgttt tggaatatgg taatgctttc
     7561 cgttggggtg aacactacgt cttgattcaa ggaactgaag gagctatcaa acttgacttg
     7621 ttcaatactg gcggtactct tcgtgttaaa ggtgaaggag aatcacactt cttagttcat
     7681 gaaactcaag aggaagatga tgatcgtaca gctatctata ccggtcgtgg tatggatgga
     7741 gcaattgcgt acggtaaacc aggagtacgt tgcccattat ggttgcaaac atgtattgat
     7801 aaagaaatgg aatatctaca tgacatcatt aaaggtggag aaattacaga agaatttgaa
     7861 aaacttctca atggtgtagc tgctttagaa tcaatcgcta ccgctgatgc atgtacttta
     7921 tcagttaaag aagatcgaaa agtaagtctt tcagaaatca caaatgctta acttttgtaa
     7981 aacagaatag taaattcttg tcattatata atttctaaag ttctgtgata caactcattg
     8041 aataaagaaa tagagatggg actgggataa tgcccagtcc cattttttat caaaaagtaa
     8101 tgagatcaaa aatgtgggag tgttgaaatg aagattatag gtatcgatat tggcggaaca
     8161 acaattaagg cagatttata cgatgagttt ggaacgagtt tgaatcattt caaagagata
     8221 gaaacaatta ttgactatga tttgggaacg aatcagatat taaatcaggt ctgtgattta
     8281 attggtgagt atactttaaa tcattcaatt gatggtgttg ggatttccac tgctggagtt
     8341 gttaatgcta atactggaga aatcatctat gcaggctata caataccagg gtatatcgga
     8401 gtaaacttta ctgccgaaat agaaaaacgt tttgggttgt atacttttgt tgaaaatgat
     8461 gttaattgtg ctgcattagg tgaattgtgg aagggacaag ccaaagataa gaaaaatgta
     8521 gtaatggtta ctattggaac aggtatagga ggcagtatta ttgtcaacgg acaaattgtt
     8581 aacggattta actatactgc tggtgaagta ggttatattc ctgtaggtaa ttcggattgg
     8641 caaagtaaag cctcaacaac cgcattgatt catttatatc aaaaaaagag cttgaaaact
     8701 aatcaaactg gacgtacttt cttcactgat ttaagatctg gagataaagt tgctgaagaa
     8761 acttttgaaa tttttgtaga aaatctaaca aaaggtttat taacgatttc ttatctactt
     8821 aatccagaaa ttctcatatt aggaggtggg attctggata gtaaggatat tttgttacct
     8881 gaaattcaaa gttctttagc taaaaatgca atggataata ggtttttacc taaaaatctt
     8941 gtggcagcta cattaggaaa tgaagctggt cgtataggag ctgtaaaaaa tttcttagat
     9001 agaatttcta ataaatagta tgtaagataa ggaggtgtca caatgactaa ctctgtattt
     9061 tcgacaatgc aagatattga gaatgttgca accgatatta taaaatcata tgataatgag
     9121 atttatactt ataaagctgt ttcccaagaa gaattggaaa aactagaaaa aagttatgat
     9181 gaaaaaagtc acgaagaatt agtttcaata gaaagcaatt tagaaatgaa acaacagaac
     9241 cttattgatg aggttaataa aacaatcaag gaaaatgatg caaatattca gtatatttca
     9301 tcaagtagga gaggagaatt tgtagaaaaa attattggta gggtggtaga aaaatatggc
     9361 cattagtcag atgaaaagaa tctctctact attttctaaa agtagtcttg atgatgtttt
     9421 aaaaactatt caagaactag agtcagtgca gttccgtgat ttaaaggttc aggataattg
     9481 gtcagaagct ctagaaaaag atgaagttgt atttccaact attcaaattt ttcatacttc
     9541 taattccaat catggggtta ttgagggaaa tgatgccttg acttatttga tgaatcaaca
     9601 acaacattta gaagcaactg tagagaaatt acaagaatac ctaccgaaag aaaacacgtt
     9661 taaattattg cagcaacctc cgataactac ctcttatgaa gaattagaga aatttggtaa
     9721 agctaatgtt gctgagggtg ttcttaaaaa agtgaatcat caaattaaca gagttcatga
     9781 attagaaaga cacattcaaa gtaataatga ggaaatagag cgattaataa agtgggaaaa
     9841 attagaaatt gttcctgcga atttagaaca attttctttc tgtaaaggaa aagtcggaac
     9901 aattccaagg actgaagata atcgcttata caatagtctt ttagaaaaca atattgaagt
     9961 tcaagaaata ttttctaatg atagagagta cggtgttgtt gttttctatc agtctagtta
    10021 ctctatagat tttgatgaat acttatttga accatttgat tattctagaa aggaattacc
    10081 gaagcagcga gtagtagatt tagatcaaga aaacatgcag ttaataactg aaaaagagaa
    10141 tattatcgca tcgttgcaag attcaaagaa atatttgata gatttacaat ggcaaataga
    10201 ctatatttta tctatctatg ctcgtcaaat ctctaagaat aactttttgt gcactccgca
    10261 tctagttgca ttagaaggat ggatagaaga aactcgtatt ttatatttta taaaagttat
    10321 ggatgagcat tttggacatt ctatttatat ttatgaatcg gaaacattga cggataatca
    10381 agatgaaata cctatcaaat taacgaatca ttctttaatt gaaccatttg aattattgac
    10441 agaaatgtat gctctgccca aatattatga gaaagatcct acacctgtat tagcaccatt
    10501 ttactttaca ttttttggaa tgatggttgc tgatttaggc tatggtttac tattgttttt
    10561 aggaacaatg ttagcattaa aaatttttca tctaccttca gcaactaaga gatttttaaa
    10621 attctttaat atattagggg tagccgttgc aatttggggt ggaatctatg gctcattttt
    10681 tggatatgag ttgccatttc atctgatatc tacaacctct gatgttatga ctatattagt
    10741 agtgtcagtt gtgtttgggt ttattacagt atttgcaggt ttgttagctt caggactaca
    10801 aaaagtaaga atgaagaaat atgcagaagc atataattca ggatttgcgt ggtgtgttat
    10861 tctgcttggc ttgttattta ttgctgttgg aatgttgatg cctgatatga gaccgttatt
    10921 tgtattaggg aaatgggtat ctatttttaa tgctgtgggg attttgattg tttctattat
    10981 tcaaaccaaa agcttgtcag gtattggagc aggattgttt aatctatata acatttcatc
    11041 ttatataggt gatttagtta gtttcactcg attgatggca ttaggattat ctggagcaag
    11101 tatagcatca gctttcaatt taattgttgg tttgtttccg ggaatattgg ctaaactgac
    11161 aattggatta gtattattca ttcttttaca tgcgatcaat atttttctat cgttactatc
    11221 aggatatgtt catggagcac gtctgatatt tgttgaattt tttggtaagt tttatgaggg
    11281 tggaggaaaa ccatttcaac ctttgaaggc ttctgagaaa tatattaagg ttattacaaa
    11341 gaattaatgg aggatatata taatggaaca tttagcaact tatttttcaa cctatggagg
    11401 agctttcttc gctgcattgg gaattgtatt ggcggttgga ttaagcggta tggggtctgc
    11461 ttatggagtt ggtaaggctg ggcaatctgc cgcagcttta ctgaaagaac agcctgaaaa
    11521 gtttgcctca gctttgatat tgcaattatt gcccggaaca caaggattat atggttttgt
    11581 tattggaatt ttaatttggt tgcaattaac tccagaactt cctttagaaa aaggcgttgc
    11641 ttatttcttt gtagctcttc caattgctat tgtaggatac ttttcagcta agcatcaagg
    11701 aaatgtagca gtagcgggaa tgcaaatctt ggctaaaaga ccaaaagaat tcatgaaggg
    11761 agcaatttta gctgccatgg tagaaaccta tgcaattctt gcttttgtcg tatcattcat
    11821 tttgaccctt cgtgtataag aaataaattt gcaattcaaa ggaggtgtct aaatgagcaa
    11881 tttagaaaac ttacgagagt ctgttattga acaagctcat gaaaaagggc gtatgaaatt
    11941 attggattcc aaaaagaaga ttgatgatga atttgaaatg caaaagtcgc tcattataaa
    12001 gaaaaaagaa gctgaacatg aacgaaagtt aaaagaattg caacagaaat atcaaataat
    12061 ttttcaacaa ttaaaaaata aggaacgcca atcaacgtta gtatcaaaac agaaaatatt
    12121 aaaagaactt tttcaatctg ctttactaga aatggaatct tggagtgcag ataaagaaat
    12181 ggagttcatc tatcgaattc tggaacgata ttcacaacaa gaggtcatag taacctttgg
    12241 ggaacggact ttagctaaat tcaatttgga acaattagag aaattgaaat tctcttttcc
    12301 aaattattta tttagtgaac aacctatctc aaatgaatca ggcttactta tttcaatagg
    12361 taa
//
LOCUS       DAVLMQ010000050        12183 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000050 DAVLMQ010000000
VERSION     DAVLMQ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12183
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.050"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VXF95_001729"
     CDS             complement(49..762)
                     /gene="rsmG"
                     /locus_tag="VXF95_001729"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HEV1082239.1"
                     /translation="MKPKTFYNLLAEQNLPLSDQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            856..1416
                     /locus_tag="VXF95_001730"
     CDS             856..1416
                     /locus_tag="VXF95_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HEV1082240.1"
                     /translation="MTWIILGVLALVVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            1418..2317
                     /gene="htpX"
                     /locus_tag="VXF95_001731"
     CDS             1418..2317
                     /gene="htpX"
                     /locus_tag="VXF95_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HEV1082241.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGACEVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALVSAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(2361..3920)
                     /locus_tag="VXF95_001732"
     CDS             complement(2361..3920)
                     /locus_tag="VXF95_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1082242.1"
                     /translation="MHYEHSRKGNHMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKILMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQKIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYESYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYLSKTGEKEELQKIQSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSSIYRLTE
                     HGLELVNLEDV"
     gene            complement(4159..4476)
                     /locus_tag="VXF95_001733"
     CDS             complement(4159..4476)
                     /locus_tag="VXF95_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000389556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HEV1082243.1"
                     /translation="MEDKKLIQLLSKLNKSYQNCKQGTADDIRLQELLNTTMQELKKT
                     EKLNNSILIDLEKFYQPTSLLIGLGSLKLNDQARTAWRNYDKFHYEHVKHVLSLYGPV
                     FGF"
     gene            4646..5188
                     /locus_tag="VXF95_001734"
     CDS             4646..5188
                     /locus_tag="VXF95_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HEV1082244.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNHLNQEILDDD
                     LVLPIENEALDLAESVSDNILLNIPIKVLTAEEEAGQGFISGNDWQIMTEEEYQAQKA
                     VKKEENSPFAGLQGLFDGDE"
     gene            5188..5817
                     /gene="nth"
                     /locus_tag="VXF95_001735"
     CDS             5188..5817
                     /gene="nth"
                     /locus_tag="VXF95_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HEV1082245.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            6028..6549
                     /gene="pyrR"
                     /locus_tag="VXF95_001736"
     CDS             6028..6549
                     /gene="pyrR"
                     /locus_tag="VXF95_001736"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HEV1082246.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            6568..7491
                     /locus_tag="VXF95_001737"
     CDS             6568..7491
                     /locus_tag="VXF95_001737"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HEV1082247.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            7541..8620
                     /gene="carA"
                     /locus_tag="VXF95_001738"
     CDS             7541..8620
                     /gene="carA"
                     /locus_tag="VXF95_001738"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HEV1082248.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEEARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRDLTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            8933..12109
                     /gene="carB"
                     /locus_tag="VXF95_001739"
     CDS             8933..12109
                     /gene="carB"
                     /locus_tag="VXF95_001739"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HEV1082249.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELGVELLGTRLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAIAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDQVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKNVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
BASE COUNT         3478 a         2393 c         2693 g         3619 t
ORIGIN      
        1 aaataagaga gcgaggttga ttttgtaaat atttttttac ttaaaaattt aaagcgggcg
       61 tttatttggc ataccagcct tacgtggata tttatttggt gtttcttttt tcttttctac
      121 cactgtgatg taacgcggat ctctatttgg tagggcgtag ctgagattgt cttcgacttt
      181 actaaaaagg agattgaggg cattcttagc ttctaacaac tcctcaggcg cattgctggc
      241 cttgagtgcc aatagttttc caccaacctt aaggtaggga atagtcaatt cagataggac
      301 ctgcatacgg gcaaccgcac gagctgttac aaaatcatat tgagcacgga agttcttgtc
      361 ttgggcaaaa tcttcggcac gtccgtggta gaaatgaact ccgttcaaat ccagttcttg
      421 agccaagagt tgtaggaagt tgatgcgctt attgagtgaa tcaataatgg tcacatctaa
      481 ctccggatag agaattttca ttggtagact aggaaatcct gccccagccc cgatatcaag
      541 aagtttgata gtttcattgg gaatcaaacc ttgaagaatg ggtgcaatcg aatcgtaaaa
      601 atgtttgaga taaacttctt ccttgtccgt aatcgccgtc aaattaatct tctcattcca
      661 ctcgaccaag agctcaaaat aacgttcaaa ttgttctttt tgctggtccg aaagtggaag
      721 attctgctcg gcaagcaagt tgtaaaatgt ttttggtttc atagttattt ccttctttag
      781 tatcatctta ttttaccaca atcatagaaa atttgatata ctggtactaa tctaaaagca
      841 gaaaggactt atattatgac ttggattatt cttggagttt tagctcttgt tgttattttt
      901 gtgattgtta gctataacgg tttggttaaa aatcgtatgc aaaccaagga ggcttggagt
      961 cagattgatg ttcagttgaa acgtcgcaat gatctcttgc caaacttgat tgagactgta
     1021 aaaggttatg ccaaatatga aggttctacc cttgaaaagg tggcagaact acgtaaccaa
     1081 gtggcggcag cgacttcacc agcagaagct atgaaagcca gtgatgccct cactcgtcag
     1141 gtttcaggta tttttgcagt tgcagaaagc tatccagatt tgaaagctag tgctaacttt
     1201 gttaaattgc aagaggagtt gacaaacaca gaaaataaaa tttcttactc tcgtcaactc
     1261 tataacagtg ttgtcagcaa ctacaatgta aaattagaaa ctttcccgag caatattatc
     1321 gctggaatgt ttggatttaa agcggcagat ttccttcaaa cacctgaaga ggaaaagtcg
     1381 gttcctaaag ttgattttag cggtttaggt gactaagatg ttgtttgatc aaattgcaag
     1441 caataaacga aaaacctgga ttttgttgct ggtatttttc ctactcttag ctcttgttgg
     1501 ttatgcggtt ggttatctct ttataagatc tggacttggt ggtttggtta tcgcactgat
     1561 tatcggcttt atctacgctt tgtctatgat ttttcaatcg acagagattg tcatgtccat
     1621 gaatggagcg tgtgaggtgg atgagcaaac ggcaccagac ctctaccatg tagtggaaga
     1681 tatggctctg gtcgctcaga ttcctatgcc ccgtgttttc atcattgatg atccagcctt
     1741 aaatgccttt gcgacaggtt ctaatcctca aaatgcggct gttgctgcga cttcaggtct
     1801 actagctatc atgaatcgtg aagaactaga agctgttatg ggacatgaag tcagtcatat
     1861 tcgtaattat gatatccgta tttcgactat tgcagttgcc cttgttagtg ctatcaccat
     1921 gctttctggt atggcaggtc gtatgatgtg gtggggtgga gcaggtcgca gacgaagtga
     1981 tgatgaccga gatggaaatg gtcttgaaat cattatgcta gtggtttccc tactagctat
     2041 tgtactggca cctctcgctg caaccttggt tcagctcgct atttctcgtc agagggaatt
     2101 tctggcagat gcatctagtg tcgagctgac tcgcaatcct cagggaatga ttaatgccct
     2161 agataagttg gacaatagca aacctatgag tcgccacgtc gatgatgcta gcagtgctct
     2221 ttatatcaat gatcccaaga aaggtggggg gttccaaaaa ctcttttata cccacccacc
     2281 tatctcagaa cggattgaac gtttaaaaca gatgtaaaag aatccagagg tcgtctctgg
     2341 atttttgcta tgttgcaaat ttatacatct tctaaattaa ctaactccaa accgtgttct
     2401 gtcaagcggt agatgcttga acagacctct tttaagaaac gacggtcatg cgaaacagtg
     2461 atgagaccgc ctggataggt tgcaaagagt tttctgattt ggggttgaga agtgggagaa
     2521 aagtttcgtg tgggttcatc cagcaggaga aagtttggtt tgcgcaggac taaatccaaa
     2581 agcaggagtt ttccctgttg tccgccagat aaggagcgaa tttgatgctg catttctgga
     2641 taactgaaat tgagactagc taggtgagat tggattttct gtagttcctc tttttcccca
     2701 gttttgctga ggtaggctat tggtgataaa tccaattgca gttttttgtg gtaatcttgt
     2761 ggcataaaac caagggaaat ctctctttta tcattcagaa gttgctttaa tttggctaac
     2821 agagttgatt tcccaacacc atttggcccg ataataccga ttttttcttg cccacggaca
     2881 gttagttgta gtttttgaac caaaactcgg tcgtcaatgg acaaattttc tttttccagt
     2941 tggactaaga ctttagaagc tggtaatggt tggatgtctg aaaagaaaag ttggatttgt
     3001 tcctcttcaa gtggcttttg agtcatggac tgagctgcct tttcgtagcg tttttcttgt
     3061 gagaggacag ttttcatctt tttagccaat aggcgaccgg cagtactgtc tttggtagct
     3121 cgaagcgcag tttctacatt ttgtttgact ctccgatgtt tttccatggt tttatcgtag
     3181 gctctttggt tgttagcagc ttgctgactt tgtttggcaa aattagcctt tctctgctca
     3241 ctatagcttt catagtctaa atgctctact agcgtttccg cttctttacg gtgtttgacc
     3301 agtcgcaagt gaacaatagt gtctgccgtt tcagaaagaa agtcttcatc atgggaaatg
     3361 aaaataacgg tttgcctggt cttttgaatc tggcctttta gccaatcaac tgtctcaagg
     3421 tctaggtcat ttgaaggttc atctaaaaat agaatctcaa agggtttggc taactcatgg
     3481 ataagctgaa ttttcaaagc ttctccccct gatagattgc caatcttttg gtcacttgcg
     3541 aaacgattgc tatcaaaatg caattcctcc gccaaacgat agaggatact gtagtctaaa
     3601 tcaatagaat ctaaaaagaa gtagtcgtgt aaagttttct ttttcagctc ctcgggaagt
     3661 ttttgaggaa tgtaggccag tgactgatag tcagattgga tgtttccctt gatagtgaaa
     3721 tcagacaaag cttcccccat taaaatttta agtaaggttg atttgccatt tccttcttca
     3781 ccaataatag caaccttttc cccgtcttgg atggtcatgc ttaggtcaga tacaagatct
     3841 cgtaaatctt tgttttgtgt gatggttaga tgattgattt ttatcatatg atttcccttt
     3901 ctagaatgtt catagtgcat aacaaaaagc tctactttac ctagtagagc ccaaagtcta
     3961 tgtcaaaaaa actctattaa catgccagaa aaagagcata aaagagcaca caaaaagaga
     4021 caaaaacaag atctactaaa taaaggttct ttatttgata gacttagttg ttcatgtctc
     4081 ccttacctcc gagtattagt atctttatat tataccttta aggaaatttt gtcaacagaa
     4141 aactggaaat tctatgctct aaaatccaaa aacaggtcca tagagactta gtacgtgttt
     4201 gacatgctcg taatggaatt tatcatagtt tcgccaagca gtgcgtgctt gatcgtttag
     4261 ttttaggcta cccagtccaa tcagaagact ggtgggttgg taaaatttct caagatcaat
     4321 taagatactg ttgttcaact tttccgtttt tttgagctct tgcatagtag tgtttagcag
     4381 ctcttgtagt cgaatatcat ctgccgtacc ctgtttacag ttttgatagc ttttatttaa
     4441 cttggatagg agttgaatga gtttcttgtc ttccatgtga gcatcctcct tgatctgatg
     4501 tactctttcc ctatagtata gcactaaaaa acaaaactgt catagtaaat atgttaaaat
     4561 tttgaatttt aattacaaag tttggtgtgc tgatttgtag ccttttcatg gtataatcaa
     4621 gagagtaaat ctttatggag gaagtatgaa attaaatatt caagaaattc gtaagcagtc
     4681 tgaaggtttg aactttgaac aaacgttaga tttagttgat gacctgcgtg cacgtaatca
     4741 agaaatttta gatgtaaaag atatccttgc agttgggaaa gtacaatatg aagaccgtat
     4801 gtatttctta gattatcaac tatcttatac cattgttctt gcttcgagtc gcagtatgga
     4861 gccagttgag ttagttgaat cttatccagt cacggaagtt ttcatggaag gtgcaactaa
     4921 ccatctaaat caagaaattt tagatgatga cttggtcttg cccatcgaaa atgaggcgct
     4981 tgaccttgct gagagtgtat cagacaatat cctgctaaac attcctatca aggtcttgac
     5041 ggctgaagaa gaagctggtc aaggatttat ctcaggaaat gactggcaaa tcatgacaga
     5101 ggaagaatac caagctcaaa aagcagtaaa gaaagaagaa aacagtcctt ttgctggctt
     5161 acaaggacta tttgacggag atgaataatg gtcttgtcaa aaaaacgagc acgaaaggtg
     5221 ctagaagaaa tcattgccct cttcccagat gccaagccta gtcttgattt taccaatcat
     5281 tttgaactcc tggttgcggt catgttatca gcccagacga cagatgcagc ggtaaataag
     5341 gccacaccag gtctctttgt tgcctttcca acaccccaag ctatgtctgt agcgacagag
     5401 agtgagattg cttcacatat ttctcgcttg ggattgtatc ggaataaagc taaattcctt
     5461 aaaaaatgtg cccaacagtt actagacgat tttgatggtc aagtccctca gacacgtgaa
     5521 gaattggaga gtttggcagg tgttggtcgc aagacagcca atgttgtcat gagtgtagga
     5581 tttgggattc cagcctttgc agtggatact catgtggagc gtatttgcaa acaccacgat
     5641 attgtcaaaa aatcagcgac gccacttgag gtggaaaagc gggtcatgga tatcttgccg
     5701 cctgagcagt ggttagctgc ccatcaggcc atgatttatt ttggaagagc catttgccat
     5761 ccaaaaaatc cagagtgtga ccagtaccca caattatatg attttagcaa tttgtaagat
     5821 gctacattga aactttttgc ttgattttaa gcatgctttg tgctatagta aatgataact
     5881 aaatattcct ttaaacctgt cccgtgaggc aggcaaggag cgcgataaag tagaagggtg
     5941 aagtctatac tgtgtgcagt agggctcgct tggctataaa tttcaagtct ccttgtttaa
     6001 ggagactttt ctttttggag gtttgtcatg aaaacaaaag aagttgtaga cgaattgacc
     6061 gtcaaacgag cgattacgcg tattacttat gagattatcg aacgcaacaa agatttgaat
     6121 aagatcgtct tggctggtat taaaactcgt ggtgtcttta ttgcccaccg aatccaagaa
     6181 cgtttgaagc agttagaaaa tctttcagtt cctgttgtgg aattggatac taaacctttc
     6241 cgtgatgatg ttaaaagtgg agaagatact tctttggttt ctgtcgatgt gacagaccgc
     6301 gaagttatct tggtggatga tgtgctctat acaggtcgta ccatccgtgc tgctattgat
     6361 aatattgtcg gtcatggtcg tcctgcgcgt gtgagtttag cagttctagt cgatcgtgga
     6421 catagagaat tgccaatccg tccagattac gttggaaaaa atatcccaac cagtcgttct
     6481 gaagaaatca tcgtagagat gacagaactt gatgaccaag acagagttct gattactgaa
     6541 gaagcttaga aagttaaagg agtagccatg tcagaaaatc aacaagcatt gaaccatgtg
     6601 gtgtccatgg aagacctcac tgtcgatcaa gtaatgaaat tgatcaagcg aggaattgag
     6661 tttaaaaatg gagcccagct tccctatgaa gaccatccga ttgtttccaa tctcttcttt
     6721 gaggattcta cacggacaca taagtccttt gaagtcgcag agattaaact tggattggaa
     6781 cgacttgact ttgatgtgaa gactagttcg gttaataagg gtgagacact ttatgacacc
     6841 attttgactc tgtctgcttt aggagtggat gtctgtgtga ttcgccatcc agaggtcgac
     6901 tactatagag aattgattgc tagtccaacg attacgactt ccatcatcaa tggtggagat
     6961 ggttcgggcc aacaccctag ccagagcttg cttgatttga tgaccattta tgaggaattt
     7021 ggccactttg agggtcttaa agttgctatt gcaggtgact tggaccactc acgcgttgcc
     7081 aaatccaata tgcagatttt gaaacgcttg ggatctgaac tctttttcgc tggacctgag
     7141 gaatggagaa gtcaagagtt tgcagactat ggacagtttg taaccattga tgaaatcatt
     7201 gatcaggttg atgtcatgat gtttctccgt gtgcaacacg aacgccatga tagtggagct
     7261 gtattttcaa aagaagacta ccatgcccaa catggcttga ctcaagaacg ttacgatcgt
     7321 ttgaaagaaa cagcaatcct catgcaccca gctccaatca atcgtgatgt agaaatagca
     7381 gaccacttgg ttgaagcacc aaaatcacgg attgtccaac aaatgaccaa tggtgtcttt
     7441 gttcgaatgg caatcttaga atccgtacta gcgagtagaa acgccaacta aaacacaaga
     7501 cgttaaaaga cgccagtgag cgtccacgag aggtgaaaat atgacaaaaa gaattctagt
     7561 attagaagat ggcacagttt ttgaaggcaa ggccttcgga gcagatattg atgtaacagg
     7621 cgaaatcgtc tttaatacag ggatgaccgg ctaccaagaa tccattacag accagtctta
     7681 taatggacaa atcttgacct ttacttatcc tttggtagga aattatggta ttaatcgtga
     7741 tgattatgaa tccattattc caacttgtaa gggagtcgtt gtttttgaag aagcgcgtag
     7801 agctagcaac tggcgcaacc aaatgacctt ggatgaattt ttgaaagcca agaaaattcc
     7861 agggatttca ggaattgata cgcgtgatct taccaagatt atccgtaagc atggtactat
     7921 gcgtgcaacc ttgacccatg ttggggacag tatggaccat gtgacggacc agctccaagc
     7981 aacagtttta ccgacagaca atatcaaaca ggtttctact aaaacgtctt atccagctcc
     8041 aggagttggt ttgagcgtgg tgctagtgga ctttggtctc aagcactcaa tcctacgtga
     8101 actttctaaa cgcaactgta acgtgacagt tgttccttat tcgacaacgg ctgaagaaat
     8161 tctccatctc aatcctgatg gagttatgtt gtcaaatggt ccaggtaacc cagaagacgt
     8221 tccacaagca ctcgacatga ttcgcggtgt acaaggaaaa attccaatct ttggtatttg
     8281 tatgggacac caactctttg caatggcaaa cggggctaag acctataaga tgaagtttgg
     8341 ccaccgtgga ttcaaccatg cggtacgtga aatcgcaaca ggacgagtag acttcaccag
     8401 ccagaaccat ggttatgcag tcagccgcga ggatttgcca gagcacttga ttattaccca
     8461 cgaagaaatc aatgacaagt cagtggaagg tgtgcgccac agataccaac ctgctttctc
     8521 tgttcaatac cacccagatg cagctcctgg gccacacgac gctagctacc tatttgacga
     8581 gtttatcgag atgatggaag tttttaaaca atcaaactaa gaacgagtaa aagctcgtcg
     8641 gagaatttat gtaactgaac acggacggaa agctcagaat gtagagaaac caacttggat
     8701 tgtcaatcct tccttgattt tctaaaattc aatcgctttc tattcgtcct ttgtatctta
     8761 tttaatgtcg ccctgagagg cgacgaatag aaaggagaag ggtgctccgt atttgctgaa
     8821 ctgaatacgg gctacggatg gtgctaaaaa gatagttatt cctagaactg acagttcttc
     8881 gtcataactc ctattttagc tttgtccgct tgacgccctt aatatcttat atatgcctaa
     8941 acgtactgat attcaaaaaa ttatggtgat tggttctggt ccgattatta ttggtcaggc
     9001 tgctgagttt gactacgctg ggacccaggc ttgcttgtcg ttgaaagagg aaggttatga
     9061 ggttgttttg gttaactcaa atcctgcaac catcatgacg gacaaggaaa ttgctgataa
     9121 ggtttacatt gaaccgatta cacttgagtt tgtgacacgt attcttcgta aggaacgtcc
     9181 agatgccttg ctaccaacac tcggtggtca gacaggtctc aacatggcca tggaattgtc
     9241 taaaaatggc atcttagatg agcttggtgt agagcttctc ggtactagat tgtctgccat
     9301 tgaccaagcg gaggaccgtg acctctttaa acaattgatg gaagagcttg agcaacccat
     9361 tccagaatct gaaattgtta acacagtaga agaagcaatt gcctttgcag cgacaattgg
     9421 ctacccagtc atcgttcgtc cagcctttac ccttggtggt actggtggtg gtatgtgtgc
     9481 caacgagaaa gaattgcgtg aaatcactga aaatggtttg aaattgtcac ctgttaccca
     9541 atgtttgatt gagcgttcga ttgccggttt caaggaaatt gaatacgaag tgatgcgtga
     9601 ctcagctgac aatgccttgg ttgtttgtaa catggaaaac tttgacccag ttgggattca
     9661 cacaggggat tccattgtat ttgcccctgc gcaaaccatg tcagactatg aaaaccaaat
     9721 gcttcgtgat gcgagcttga gcattattcg tgccctcaag attgaaggtg gatgtaatgt
     9781 tcagctagct cttgatccta acagcttcaa gtattatgtt atcgaagtaa accctcgtgt
     9841 atcacgttcg tcagcccttg cttctaaagc gacaggatat ccgattgcta agttggctgc
     9901 caagattgca gtaggtttga ccttggatga ggttataaac ccagttacag gttcaaccta
     9961 tgccatgttt gaaccagccc ttgactacgt agttgctaag attccacgtt tcccatttga
    10021 caagtttgaa aagggtgaac gccgtctcgg tacacaaatg aaggcgactg gagaagtcat
    10081 ggcaatcggt cgtaacatcg aggaatctct tctcaaggcc tgccgctccc ttgaaattgg
    10141 ggtgcaccac aatgaaatac ctgaacttgc agcagtttct gatgatgcct tgattgaaaa
    10201 ggttgtcaaa gcccaagatg accgtctctt ctatgtgtca gaagccattc gccgtggtta
    10261 cacacctgaa gaaattgcag agcttacaaa aattgatatc ttctatcttg ataaactctt
    10321 gcatatcttt gaaattgagc aagaattggg tgctcatcca caagatctag aagttttgaa
    10381 aacagccaaa cttaatggtt tttcagaccg taagattgct gaactctggg gaacgactga
    10441 tgatcaagtt cgccaacttc gtttggaaaa caagattgtc ccagtttata agatggtaga
    10501 cacttgtgcg gcagagttcg actctgaaac gccatatttc tattcaacct atggttggga
    10561 aaatgaatct atcagatctg ataaagaatc tgtacttgtc ctaggttcag gtccaatccg
    10621 tatcggtcaa ggggttgagt ttgactacgc aaccgttcac tctgttaagg ctatccaggc
    10681 agctggttat gaagctatta tcatgaactc aaacccagag accgtttcaa cagacttctc
    10741 tgtatcagat aagctttact ttgagccatt gacattcgaa gatgttatga acgtcattga
    10801 cttggaacaa ccaaagggag ttatcgttca gttcggtggt caaacagcca tcaaccttgc
    10861 ggagccattg gcaaaagcag gtgtgaccat ccttggtaca caggttgctg acctagaccg
    10921 tgccgaagac cgtgacctct tcgagcaagc tctcaaagaa ttggatattc cacagccacc
    10981 aggacaaacg gctaccaatg aagaagaagc agctcttgca gctcgtaaga ttggcttccc
    11041 agttcttgtc cgcccatctt atgtacttgg tggacgtgcc atggaaatcg ttgaaaacga
    11101 agaagacctt cgttcttaca tgcgaactgc tgttaaggct agtccagacc acccagttct
    11161 tgtcgactct tacatcgttg ggcaagagtg cgaagttgat gccatttcag atggtaaaaa
    11221 tgtactcatt cctggtatta tggagcatat cgaacgtgct ggtgtccact caggtgactc
    11281 aatggctgtt tacccaccac aaaccttgtc gcaaaaggtt caggagacca tcgcagacta
    11341 caccaaacgc ttagcaatcg gtcttcactg ccttggaatg atgaacatcc agtttgttat
    11401 caaggatgaa aaagtctacg ttattgaggt caatccacgt gccagccgta cagttccatt
    11461 cctatctaag gtaaccaata ttcctatggc tcaagtagcg accaagctca ttcttggtca
    11521 aagtttatca gaacttggct accaaaatgg actttaccct gaaagcaccc gtgttcatat
    11581 caaggcacct gtcttctcct ttaccaaact agctaaggta gacagcttgc tcggtcctga
    11641 aatgaagtca acaggtgaag ttatgggttc tgatgctact ttggaaaaag ctctctataa
    11701 agcctttgaa gcttcttatc tacacttgcc aacttttggt aatgtcgtct ttaccatcgc
    11761 tgatgatgcc aaagaagaag ccttgaactt ggctcgtcgt ttccaaaaca ttggttatgg
    11821 aatccttgcg acagaaggga cagcagcctt ctttgctagt catggcttgc aagcccaacc
    11881 tgttggtaag attggtgatg atgataagga tatcccaagt tttgtacgca aaggaagaat
    11941 tcaagctatc attaacacag taggaacaaa acgaactgct gacgaagatg gtgagcaaat
    12001 tcgtcgttca gccattgaac acggggtgcc cctcttcaca gcgctagata cagctaatgc
    12061 catgcttaag gtacttgaaa gtcgtagctt tgttacagaa gcgatttaaa tagaaaaata
    12121 aggtatagca gactgaattt agaacagtac acagggatac taaaatattt ctagaaatta
    12181 att
//
LOCUS       DAVLMQ010000051        11822 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000051 DAVLMQ010000000
VERSION     DAVLMQ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11822)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11822)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11822
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.051"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..1288)
                     /locus_tag="VXF95_001740"
     CDS             complement(<1..1288)
                     /locus_tag="VXF95_001740"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HEV1082250.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRSYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIAMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKEA
                     VENAPSILDFLDEESQAHFDAVRQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVSYFGGPETAGFGFGLGVERLLLILEKQGVTLPIENALDVYIA
                     VLGEGANIKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFVAKTLITLGESEVES
                     GQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(1366..2613)
                     /locus_tag="VXF95_001741"
     CDS             complement(1366..2613)
                     /locus_tag="VXF95_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HEV1082251.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMLLPTLFTVFAGIRADYTRAKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SSLCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAIIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFLTILNLKNDI"
     gene            complement(2804..3655)
                     /gene="rgg"
                     /locus_tag="VXF95_001742"
     CDS             complement(2804..3655)
                     /gene="rgg"
                     /locus_tag="VXF95_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HEV1082252.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATRGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEELLFLARGFQYDTDSELRKEITDVLKPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVCIFEMLGCNKSAEY
                     YRNTTEC"
     gene            3779..4120
                     /locus_tag="VXF95_001743"
     CDS             3779..4120
                     /locus_tag="VXF95_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HEV1082253.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
     gene            4178..4258
                     /locus_tag="VXF95_001744"
                     /pseudo
     CDS             4178..4258
                     /locus_tag="VXF95_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4373..6076)
                     /gene="ilvD"
                     /locus_tag="VXF95_001745"
     CDS             complement(4373..6076)
                     /gene="ilvD"
                     /locus_tag="VXF95_001745"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HEV1082254.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETSIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(6309..7241)
                     /locus_tag="VXF95_001746"
     CDS             complement(6309..7241)
                     /locus_tag="VXF95_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HEV1082255.1"
                     /translation="MMRSTKELQHVYRDFLLEANQSYSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDLVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSALCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(7238..8095)
                     /locus_tag="VXF95_001747"
     CDS             complement(7238..8095)
                     /locus_tag="VXF95_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HEV1082256.1"
                     /translation="MILSKNREDELRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNPGDFVEKFSAFGFESIRIKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEERQMLTSVVER
                     LSQELEETE"
     gene            complement(8099..9445)
                     /locus_tag="VXF95_001748"
     CDS             complement(8099..9445)
                     /locus_tag="VXF95_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1082257.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATALIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFITKPSAKEE"
     gene            complement(9458..9742)
                     /locus_tag="VXF95_001749"
     CDS             complement(9458..9742)
                     /locus_tag="VXF95_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1082258.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(9746..11776)
                     /locus_tag="VXF95_001750"
     CDS             complement(9746..11776)
                     /locus_tag="VXF95_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HEV1082259.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
BASE COUNT         3801 a         2544 c         2006 g         3471 t
ORIGIN      
        1 attgagtata aaatcctagt ttttcaaaga tttctgagaa gttttggctg attgtctcaa
       61 gtgacacttg cacttcttct cgagtttggt tgttcttgac cgtcacttgt ccgctttcga
      121 cttcgctctc tcctagggtg atgagggtct tagccacaaa gacatcggct gacttgaact
      181 gagcttttag tttacggttg aggtaatcac gctctgcttt gaaaccttgt tggcgaagag
      241 cctgtactaa ttccaaggcc ttgatatttg ccccttcgcc caagactgcg atatagacat
      301 ctagggcgtt ttcgataggg agggtcacac cttgcttttc aagaatgaga agcaggcgct
      361 ctacaccaag tccaaaacca aatccagcag tttcagggcc tccaaaataa gaaaccaaac
      421 catcgtaacg accacccgca cagacggtca ggtcattgcc ctcaatctct gtgataaact
      481 cgaaaatggt gtggttgtag tagtccagac cacgcaccat attggtatcg atgatgtaat
      541 ctactccaag attttccaac atctgacgca cagcatcaaa atgagcttgg ctttcttcat
      601 caagaaagtc caagatagac ggcgcattct ctactgcctc cttgtcttct ttttccttag
      661 agtccaagac acgaagagga ttttcctcca agcgacgttg gctatcctta gacaaggtct
      721 ccttgagcgg tgtcaaatag tcaatcaagg cttggcggta ggctgcacgg ctctcaggat
      781 ttccaagagt gttgaggtgc aatttgacac cttgaatacc gatttccttc aaaaaatggg
      841 ctgccatagc gattgtttcc acatcggtag ctggattgct agagccaaaa cactcaacac
      901 caatttggtg gaattggcgc aagcgccctg cctgtggacg ctcataacgg aacataggtc
      961 ccatatagta gaacttgctt ggcttttgca cttctggggc gaagagttta ttttccacat
     1021 aggaacggac aacgggcgca gttccttctg gacggagggt aatatgacgg tcacccttgt
     1081 cataaaaatc gtacatttcc ttggttacga tatccgttgt atctccgaca gagcgactga
     1141 taacctcgta atgctcaaaa ataggcgtgc gcacttctgc atagttatag cgcttgaaaa
     1201 tctcacgggc aaagccctca acgtactgcc acttagcaga ttcagcaggt aaaatatcct
     1261 gcgttccttt tggtttttgt aatttcatag ggaatcctct ttaaacttaa tagtcttatt
     1321 ttaccacaaa taaagggatt aaaacagtaa gaaaaaaatt aggatttaga tatcattttt
     1381 gagattaaga attgtcaaaa aaatagctag caaggaaaga ccaacaaata gcatccaagt
     1441 caactgtata ttccatacgg ctactagtga aaaacaagct gttcccacag gtatggataa
     1501 ggtaaacaat agacctaaaa aattactagt acgagctaga acctctggag ctagattttt
     1561 catgagcatg gcactaatct ttggttgaac tttaccagac acatacaggg taaagaagag
     1621 aaatagcaaa ccaagcacga cttgattgaa taaattagcc aaaccaacta gactaagtcc
     1681 tacggtcgcc cacatcatca atctaggcaa ggactgcttc ccaaaataat cattgcccgt
     1741 aaggctactg atgatgattg ctactaaaac acagaattga ttgataaata gtgcctctgt
     1801 ataagaaaaa ttcaagagag aatggctcaa aaagaagata ttataaattc cacccaaagc
     1861 gccacccaag gaattaataa gcaagacagc aaagagcata aaaccaaagt ttttctgtcc
     1921 acttttaaga aaaacgagac gtaaatttcg gtaaattgtt aggaactggt ctttgataga
     1981 aagcttctca ttttttaagt tttcaccatc agcagatgac attgacaggc tcaatttgct
     2041 ttttcctaaa aagaggatag tggctgatac taggaaaaag caggcattga ttcccgcaac
     2101 gagagaaaaa ttgttgaccg atagagctaa gagccagact ccgaaagctt gaccaccaat
     2161 agctgaaata taggtgatga actgtgaaaa agaataagcc tccatcaaat catcttcagc
     2221 tactttttcc ttaataagag gcatacgcag gccacctgca aaatcactga tgatatcact
     2281 aatgacattg atcaaacaca ggctagaaaa ggcaaataaa ctagcttgct gaacaactag
     2341 ggctgccaga aaaaataaaa ccgcctgaaa caaaccgcta tagaccatcc atttgacctt
     2401 ggccctcgtg taatctgccc gaatccctgc aaaaactgta aagagagtcg gaagaagcat
     2461 gacaatattc gccatagcaa cagcaaaaga tgcttgtgac aaggtcgatg catagacgat
     2521 aaagaccaga ttgaaaatcg aagcaccaaa agcattgaag aagcgtgata aagtcaaaat
     2581 tctataagct ggatttctaa acaatagttt catagataat ctccctcctt gttctaagtt
     2641 ctacatcaag aatagcttta gtatagcact tatgaatttg cgaaacgatt cttttgaata
     2701 tatgcaacaa ataaaatgag caaaaaaacg atagaacttt tgtaatgacc tgagagaggg
     2761 caatagttct atcgcttcaa attttttctt ggtttgcaga tattcaacat tcggtcgtat
     2821 ttctatagta ttcggcagat ttattacagc caagcatctc aaaaatacag acagcatcct
     2881 ccatcttttt ctggccttcc ttgactctac cttgcttgct atcaaggaga ccttctgccc
     2941 acagataaac aattcggaaa taggtctcat tttccttgta gaaatgctct tcgataacac
     3001 gtttaaaata ataggcattg gtaaattctt cacactcaat actagctaaa aagccattca
     3061 atagtatagt atgaaaaagg tttcgattgc cagacatttc cattagaaaa tcagatttac
     3121 gtaccatttc tcgtacatat ctagtaaaaa gagaaacaga taaaaatgga gaactgactg
     3181 aaaataaatt gagttcatag attccccaga tctcggtaga aaacaaataa tcatgaagga
     3241 cttttccttc ctctgctgtt aagtctaccc tttcatctat gctcttcata taagacttga
     3301 taataatggc atttagaata tgtttctgtt tgttgtgaga atgggcatgc ttttgatact
     3361 ccctgcgata taagtcctca agaggtgcta tattctttgg tttcaagaca tctgtaattt
     3421 cttttctcaa ctcagaatct gtatcatact ggaaacctct cgccagaaag aggagctcct
     3481 ccacactggc agatatattt tccagagcaa atagaaactt ttccaccgaa agctcactct
     3541 gacctgtttc aaaacgggac aacatagacg gcgaaaattg tcctctggtt gcttgtctca
     3601 gtgagatatt tcttgactct cgtaattgtc taaagacttt tccaatctgc tccatagact
     3661 tccccttgat tccgtatttt cttcatttta tcatattttt cagaaaattc atcaaaaact
     3721 tgccaaattg tcagaattat gagaaaatag aggatattta tcacgtggag ggactgctat
     3781 gagagacgat atcaaaatca atgaccgtgc tttggccttg caagaccaaa ttatcgaaaa
     3841 actagagaaa gtttttgata cagatgtgga attggatgtt tacaatctag gtctgattta
     3901 tgaaatcaat ctggatgaaa cggggctctg caagattgtc atgaccttca ccgatactgc
     3961 ctgtgattgc gccgaaagcc tgcctattga aatcgtggca ggtctgaaac aaatcgaggg
     4021 tatcaaagat atcaaggttg aagttacctg gtcgcctgct tggaaaatca cacgaatcag
     4081 tcgctatggc cgtattgccc ttggactacc acctcgttaa gcaggccaat cacttttaaa
     4141 gatgaaaaaa gcaagccgaa aatggcttgc tttttgatac tcaatgaaaa tcaaagggca
     4201 aactagaaaa ctagccgcag gttgctcaaa acactgtttt gaagttgtgg atagaactga
     4261 cgaagtcagc tcaaaacatg gttttgaggt tgtagatgaa actgacgaag tcagtaaccg
     4321 tactacggca aggcgacgtt gacgtgattt gaagagattt tcgagtatga gtttattttt
     4381 tacctgactt gtccatattc cagaagtctg tcacggctcc gcgtgaagca gatgatacga
     4441 tgtgggcata tttaccgagg acaccacggc tgtaaagtgg tggcaaggtt gtttctgcct
     4501 tgcgtttttc aagttcttct tcggatacgg ccatggaaat ttctttggta tcttggtcaa
     4561 ccgtaacgat atcgccggta cggagatagg caattggtcc accatcctga gcttcaggag
     4621 cgatatgtcc aacaaccaga ccataagtac caccagagaa acgtccgtcc gtcaagaggg
     4681 ccaccttatc tccctgacct ttaccaacaa tcattgaaga aagtgacagc atctcaggca
     4741 taccaggacc acctttaggt ccaacaaaac gaacaacgac tacatcgcca tcaacgattt
     4801 catctgtcag aacggcctga atcgcatctt cttctgagtc aaagacctta gctggcccaa
     4861 cgtgacgacg cactttaaca cctgatacct tggcaactgc accgtcagga gcaaggttcc
     4921 cgttcaagat gataagcgga ccatccgcac gttttggatt ttcaagtggc atgataactt
     4981 tttggcctgg agtcaagtct gcaaagtcag ccaagttttc agctacagtc ttaccagtac
     5041 atgtgatgcg atctccgtga aggaaaccat ttgccaacaa gtacttcata accgcaggga
     5101 caccaccgac ttcgtagagg tcttggaaga catactgacc agatggtttc aagtcggcca
     5161 agtgaggcac acgttcttga atcgtattga agtcctcaag tgacaagtca acatttgcgg
     5221 catgggcaat ggcgagcaag tgaagagtgg cgtttgtaga accaccgaga gccatcgtta
     5281 cagtaatagc atcttcaaag gcttcacgag tcaagatatc tgatggtttg agaccaagtt
     5341 ccaacatctt aacaacagca cgtcctgctg cttcgatatc ttctttctta tcagctgatt
     5401 cagctgggtg agaggatgac cctggcaaac tcatccctag aacttcgata gcagttgcca
     5461 tggtattagc agtatacata ccaccacaac caccagggcc agggcaggca ttacattcaa
     5521 gacgtttcac gtcctcagct gtcatgtcac cgtggttcca ttttccgata ccttcaaaga
     5581 cagaaaccaa gtcgatatct ttaccatcaa gatttcccgg tgcaatagtt ccaccatagg
     5641 cgaaaatagc tgggatatcc atattagcaa tagcaatcat agatccaggc atgttcttgt
     5701 cacagccacc gatagcgacg aaggcatcca cgttgtgacc actcatagcc gcctcgatgg
     5761 agtccgcgat gatgtcacga gatgttagag agaaacgcat accaggcgtt cccatagcga
     5821 tcccgtccgc tacggtaatg gttccaaact gtacaggcca agcgcctgca gatttgacac
     5881 cttctttagc cagtttcccg aaatcatgca agtgaatgtt acatggtgta ttttccgccc
     5941 aagtcgaaat cactcccaca atcgatgttt caaagtcctt atctgtcata ccagtcgcac
     6001 gaagcatagc acggttaggt gatttaacca tgctgtcata gatgctactg cggtgacgtt
     6061 tatctaattc agtcatctta tccctcccat ttcagttttt actattatag cacaatttaa
     6121 aggcaatgaa cagaataaaa ttcttgaatt ttcagaaaat tctatacgca tgtgaaatat
     6181 ttaaaattaa aaacaacaaa gcggattagt gcactttctg atgaccagaa tatgcttttt
     6241 aatccgcttt ctttaaataa cgtaatgtaa tttttacaga aattctttca gataagtgta
     6301 tttaacatct atcttgcatt ataaatttct agaaccttct cttttatatt cgattcactc
     6361 aaaccatact cattaagaag ataatccatt ttccctactt gaccaaatct ttcttgaaca
     6421 cccatccgat gaatttttgt tattccatca tcagagaata attcacataa agcactgcca
     6481 attccaccta tctgattgtg gttttctaca gtaaatatag tttttccact taacattgtt
     6541 tttatctgtt ctggtatcgg tttgattcta aataaatcta tcacacctac tgaataacct
     6601 aatttagaca gttcatctgc aactcgaata cttggagcaa ccattatacc agaagcaacg
     6661 attacaagat cttcaccatg ccttaactca atgtagcctt tagaaaaatc ttctccacct
     6721 tgatacacag gaactggagc ttttctaatt gttcgaatat attttagtcc ttttaagtct
     6781 aatgtctggt tcaatatttc acgaaattgg atatcatcag ttgcttcaaa aatgatcgat
     6841 ttaggaatta aacgtaacaa tccaatttct tcaaatggca tatgtgtccc accattcatt
     6901 tctgcagtta ctcctgcatc tgatccaatc acagtggcat ccaattgtgc gtatccaaga
     6961 gaaataaata attgatcaaa tactcttcgt gaagcaaaag gaccaaatgt atgaagataa
     7021 ggtctaaacc cctgaataga caagcctgct gcaaggccga ccatttctgc ttccataatc
     7081 ccaacattca cataacggtc tccaaagtcc ttttcaagat tatgagtagc catcgaactt
     7141 gacagatcgg cttctaagac tactatatca gaataacttt gattagcctc taaaaggaag
     7201 tctctatata catgctgtaa ttctttcgta cttctcatca ttctgtttcc tccaattcct
     7261 gacttaatct ttctacaact gaagttaaca tttgtctctc ctctacagta gggcgaagat
     7321 gatgattgga tttcatttct tccagctctt gaaccccttg acctttaata gtatctaata
     7381 caatgcactt aggtgatgaa ttatttgact gttttaattg gacaatccct tcataaattt
     7441 ctctaatatc tgaacccttg atcctaatgg attcaaatcc aaatgctgaa aatttttcta
     7501 cgaaatcacc tggattacaa atatcctttg taaaaccatc taattgtttt ttgttatcat
     7561 caacaaatac aattaagttg gataactgtt gatgagaagc aaactgtata gcctcccaac
     7621 attgtccctc atttaactca ccatctccaa caatagcata agtataaaag ggactctttc
     7681 ttattctctg accatatgca agtccagttg caacactaat tccttgtcct aaagagcccg
     7741 ttgtcatatc tatgcctggc gttagatttc tatcaggatg agacggtaat ttggttccat
     7801 ttgtatttaa agaatataag aattctttgt caaagaaacc attcaaatag agtgtactgt
     7861 atagagctgg tcctccgtga ccttttgata atatgaaata atctctatct cgtgctgcaa
     7921 atatttctgg agtcattggc attatttcac cataaagcac tgctaaaact tctacgatag
     7981 acagacttcc tccgtaatgt ccgaatccaa gatgattcaa tgttctaaga gtatttaatc
     8041 ggatgttagt cgcaaatttt cttaactcat cttccctatt tttacttaaa atcatccctt
     8101 attcctcctt tgcagatggc tttgtaataa aggatactcc aaacataact gctagaataa
     8161 gaacaagacc aatcacaatg cctgcttgtg agccaaattg atttaacatt cctaaaataa
     8221 ttcctgatag accaaaatct gcatctgaga aagttgatcc ttggaaacca agtcctccca
     8281 aaactggcat taaaaagact ggaagaaaac tgattaaaat accttgtaaa aatgctccaa
     8341 tagtggctcc acgaacacca ccagatgcat tcccaatgac acctgcagtc gctccacaga
     8401 agaaatgagg cacaacacct ggtaagataa caaccgttcc tgaagcaatc ataattgcca
     8461 tacttactaa accaccaaca aaactagaga taaatccaat tagaactgca ttgggtgcat
     8521 aagtataaac aatcggacaa tccaaagcag gttttgaatt aggtacaaga cgctctgaaa
     8581 tacctttaaa ggctggaaca atttcgccca aaataaggcg aacacctgct aaaataacaa
     8641 atacccctgc tgcaaattga cctgctaatt gtaaagcata aactagacca cttgtaccac
     8701 tactgatttc tttttctata tattctgacc ctgcaaagat agctacaata atgtaaataa
     8761 ctgccatgga taaagtgata ctaacagtac tatcacgtaa aaaagctaaa ctctttggaa
     8821 atttaatgtc ctctgttgat tttgatttgt caccgataag gctaccagta aaaccactca
     8881 accaatatcc caaagaactg aaatgaccta aagccacctt gtcatttcca gttaattgaa
     8941 ccatatattt ttgaacaaat gctggggaaa tactcataat aataccgagt gctaatcctc
     9001 ctagtaagat aagaggcaag ctagtaaagc cagcaactga taaaatgacc gcaatcatac
     9061 atgccatata tagagtgtgg tgccctgtta aaaaaatata tttaaatcga gtaaaacgag
     9121 cgattaagat attgaacacc atgcctgcaa acataatcag tgcagtagct gagccatatg
     9181 ttgttaaagc tacagctaca attgcttcat tattcggcac aacgccagat aaatgaaaag
     9241 catgctcaaa catggtacca aatggattta aagaattttg tacaattcct gcaccaccag
     9301 atacaactaa gaaaccaaca aaggtcttaa ttccaccttt aataatatca ggtaatttct
     9361 tcttctgaag aactaatcct aaaattgcaa ttaaagctac taaaatagct ggtgtactaa
     9421 caatatccaa tatgaacttc atcataacgc tagcctccta tataagtcct ttttcttcac
     9481 aaagtttagt aattaattct cgtagttcat ccatatcaat aatactattt aagatacgaa
     9541 catctccaag atgactagct gaatcagcta gatcacgacc aacaatccaa atatcagctg
     9601 catttggatc tgctccacct aaatcataat gttcaacttc tacatccgaa acattcaaat
     9661 cactcaatac agattcaata ttcatctgta ccataaaact tgaacctaat cctgaaccac
     9721 aagctgtacc aatttttaac attatctaat cctcctgttt aattatcatt ttaatgtcat
     9781 catagttttt tgatgatatt aaagtttgaa catgattttt atctcttaaa attgttgtta
     9841 aatgtgacaa agcctttaaa tgactctcat tatcaatggc tgcaatacaa atcaacaatc
     9901 ttacctcttg ttctggatta tccaataaat aaatcggttc ttccaaaact aacattgaca
     9961 ttcctatttc attcacacct tcatctggcc gagcgtgagg aattgctact cccttcccta
    10021 aattaataaa aggcccaaac tcttctactt tttgaatcat tgcctcaggg tagttctcag
    10081 ttatcttatc ttgatccaaa agcggtttag ctgctaaacg aatcgcctcc ttccatccta
    10141 atttttgcga actaacctga taggtttctt tggtaatgag ttgttctagc actggtacaa
    10201 tttcctttct atcatttttt tggtaaagat aattctttaa cgccaatctt aattccaatt
    10261 cttgtgtaat aattccatat cttttgacaa tattcaggat ttgttcaatc tcaaaatccc
    10321 catactctaa attcggaaaa tcttttaaca ctagttctac tagttgtatt gcttgctctt
    10381 cagtcatcat aaccgaaact agataatttg gcttttctgt ctccaccttt atggtagaaa
    10441 aaaccatatc atagtcacta ctagctttca cctgtaaatc atcaatcttt gaggttccta
    10501 taaactcaat ttgaggaaat aatgctaata gattctcttt taacatcaat gaagaactaa
    10561 caccattagg acaaatgatt gctgctttat agcatttttg aggcaaagta tctgctttct
    10621 ttaaataacc tccgaaatgg ataacaaaat atgctgtttc actatcaggt atgggattgt
    10681 caatagcgtc catcaagggc atcaaagaat ctttgactaa ttcaaataaa tcaggataat
    10741 gttctttaac atgcaataca tattcatttg aactaggtag gccgaacttt aatctatagt
    10801 aagccggtat aaggtggcgg cgaagatttt ctctcaatcc ttccctttgt ttaaaatgta
    10861 acaaagaaat atcttccatt ctacttataa tagcctctgt taattgatta aagtaaaccg
    10921 gagcaacatc tacttcacct tcaaagcaac ttgataataa aacggtgata tagcgataat
    10981 catcctcaga aaacaccgta tctataattc ccaaatcaac cactgtatcc aataaaatag
    11041 tcgttatatc ttgaataaca ggagatacta atgtctctga aagacatact ctttcaacat
    11101 ccctttgata cctacacaga atgaatacta aaccgaaaag gcaaactttt aattgattaa
    11161 caataggtac tagctgtagc ttctcataat aatctttaac tacctgattt atcaaatcat
    11221 aagttaatga atacccccaa ctggataaaa cataatccaa accccaaatc cctatggagg
    11281 attccagcaa ctcactaacc atttgaaaag ctaagcggtg cttattccac tctgaaccgt
    11341 gtaaagtata accttttgct ctactgtacc ctagctccaa atcattatct aacataatct
    11401 ttcttaatga ttgaatatca gataaggttg tattcttact tactttcaaa aagtcttggt
    11461 aatgattatt cgatataaaa tctaatcggc aaaaagtgta aagatagatt aaagctaagc
    11521 gagtcgactt tggtaaaacc aattcatccg acttaataat atctgtcaaa gactgcttcg
    11581 tacgatttga taaactatag cgaccttgtt ttttatccag cactatccct ttattagcta
    11641 gataaggcac taaataatct attccttctt tgacttcctt tataggtaag ctcaccttaa
    11701 cagataattc atataatgat agctcacaat gatccatcaa agtcatcaaa ataactagtg
    11761 ctctataatc aaacatttct cttcctttct aactacaatt atagtgtaaa aattataaga
    11821 at
//
LOCUS       DAVLMQ010000052        11723 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000052 DAVLMQ010000000
VERSION     DAVLMQ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11723
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.052"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            79..606
                     /locus_tag="VXF95_001751"
     CDS             79..606
                     /locus_tag="VXF95_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082260.1"
                     /translation="MLIVSAIPSVSAVYASEQVSQIETNMELQPVTSLTEEQINTLAN
                     EIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGITVNQMGALLDTAIALA
                     LGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALEFAMNLLSPGTYLAQL
                     WDKNDAIPNNGRINF"
     gene            complement(1651..3909)
                     /gene="glgP"
                     /locus_tag="VXF95_001752"
     CDS             complement(1651..3909)
                     /gene="glgP"
                     /locus_tag="VXF95_001752"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HEV1082261.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVRSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(3935..5452)
                     /gene="malQ"
                     /locus_tag="VXF95_001753"
     CDS             complement(3935..5452)
                     /gene="malQ"
                     /locus_tag="VXF95_001753"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HEV1082262.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGDVKDFEKFAQDNQSWLELFAEYMAIKEYFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            6002..7273
                     /locus_tag="VXF95_001754"
     CDS             6002..7273
                     /locus_tag="VXF95_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082263.1"
                     /translation="MSSKFMKSAAVLGTATLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKVTLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIVGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            7384..8676
                     /locus_tag="VXF95_001755"
     CDS             7384..8676
                     /locus_tag="VXF95_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1082264.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            8678..9520
                     /locus_tag="VXF95_001756"
     CDS             8678..9520
                     /locus_tag="VXF95_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1082265.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            9773..10573
                     /locus_tag="VXF95_001757"
     CDS             9773..10573
                     /locus_tag="VXF95_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HEV1082266.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTDKVVQDLSEHATIVDGTLTYTGTASQAPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            10583..11569
                     /locus_tag="VXF95_001758"
     CDS             10583..11569
                     /locus_tag="VXF95_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1082267.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNDNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT         3505 a         2467 c         2184 g         3567 t
ORIGIN      
        1 tgtaagcaga tacaaataaa aaggagaaaa gctcatgaac aaattaatga aatttatttc
       61 ggttttttga cgtcaattgt gttaattgta tcagcgattc caagtgtttc agctgtatac
      121 gcttctgaac aagtatcgca aattgaaaca aatatggaac ttcaacctgt cacttctcta
      181 acagaagaac aaatcaatac acttgcaaac gaaatccaat cttttcatcc agacgtctca
      241 caacaatgga tcaaagaagt aattaaccga caattacaag gcgattatac aatcccacct
      301 acatactctc catttagagc agcttggcaa ggtattacag ttaatcaaat gggtgctcta
      361 ttagatactg caatagcttt agccttagga ggaactactg caggccttgc aaatctaatt
      421 aaagtaaaag gaaaacatgc agcaaaaagt gctattcgtt cagcaatttc tagatatcta
      481 ggtagttggt ttgtaaatga tgttgcttta gaattcgcta tgaatttatt atcaccgggg
      541 acttatttag cacaattatg ggataaaaat gatgccattc ctaacaacgg aaggattaac
      601 ttttaatcat gagatataca ataaaattaa ttgggtataa cgtattttcg ttgtttatat
      661 tctttatctt atcaatgttg tttaaagttc cctttaggtg gtggatcagc attgcaatga
      721 cgacttcgtc gtacattgta tataattact taaagaaaaa gagagaaaag gaatgatctt
      781 ataccagatc attccttttc tgctttctgt aaatccctcg gagtgtgttt ggcgctttga
      841 tacgaagtgt caaagctgta taaacgttac tatttccaaa aaagtaacag aaaattcctg
      901 ctttgtagga ctgctttggg tgagtaatag acatgtcgac tcaccctatc tcctgatggc
      961 gaaaagaatt tagcaatgat gcaagttgtt ctgaactcga gaaaaaacat gccgaaatcg
     1021 aagaaaagcg tgcagaactt gaagcgaaga agcaagaaat gttgaagcgc ttggataaat
     1081 agaatttaga aaacagaaaa aactaaaaag aatgtagggt ttatttccct acattcttaa
     1141 aataacttag tacataaatg acaatgctgc cactgccgtc aatattgcaa aaactatttt
     1201 ccaaattttt ttattttttc caaaaatctt atcaggtaac aagcttatta caagaaaggt
     1261 aataaacaac accaatttaa gtgtgtatat cataaaaaca ccttctttcc tacaattata
     1321 ttataatact ttatgtaagc gaatacaaga gatatgaggt aaccaactac gaaaaaatat
     1381 aaggctgaag acagtaaaaa ccagcattta aagccttcac tgtatctagg atttccctat
     1441 ttttagacaa gattgaccca aatccacagc atttaaaaaa gcgaatttca atcgaaactc
     1501 gcttttttac aagatgtatt agtataaatt tgtatcttat actcaatgaa aatcaaagag
     1561 caaactagga agctagccgc aggttgctca aagcaccgct ttgaggttgc agataaagct
     1621 gacgtggttt gaagagattt tcgaagagta ttagttcaag tgccagatgt cttcgttata
     1681 ctgagcgatt gtacggtcag atgagaagaa tcctgcttta gaaatgttaa cgatgacttt
     1741 atccaaccat gcgtcacggt cttcgtagtc agcaagcatt tgctctttga ctttgatgta
     1801 gtcttccaaa tcaagaagag tcatgaacca gtctttgttg atcaattcat tgtaaagacg
     1861 ttccaagcgc tctttgtttc cagctgcaag aactgcatca ctaacgatga agtcaaccaa
     1921 tggtttgata gcttcacgag cgtagaattc gcttgatttg taagctgctt ttgcgtaaag
     1981 gtcgataaca gtttctgaat cttcaccgaa gatgtagatg ttttcttctc caaccaactc
     2041 agcgatttcc acgttagcac cgtccatagt accaagtgtc aaagctccgt tcaacatgaa
     2101 tttcatgtta ccagtacctg aagcttcttt agaagcaagt gagatttgtt ctgagatatc
     2161 acatgctggg ataaggaaac ttgctgcagt aacgttgtag ttttcaacca taactacttg
     2221 caagtgtgga gctactgctg gatcgttagc aataacttct gacatgcaaa ggattaaatg
     2281 gataatgtct tgagcgattg tgtaggctgg agctgcttta ccaccaaaga agattgtgat
     2341 tggacgagca gggatgttac cagctttgat gtcaaggtat ttgtggatca cgtacaaagc
     2401 gttcatttgt tggcgtttgt actcatgaag acgtttgatt tggatatcaa agatagaatt
     2461 tgaattgatt tccacacctt ggtgttcttt caagtgacga gccaatttac gtttgttgtg
     2521 agccttgatg ctttccaatt tttctttgac agctgctttg tcttcataag acaaaagttt
     2581 ttcaagctca tctgcttcat ggtgccaacc atctccaaga atctcatcta agtagtgaga
     2641 caatcttggg ttagcatgca taagccaacg acggaaagtg ataccgtttg ttttgttgtt
     2701 gaacttttct gggtaaaggt cgtagaaggc tttcaactca gaatttttca agatttcagt
     2761 atggagtgct gcaaccccgt taacactgta tccgtagtgg atatccatgt gagccatgtg
     2821 aacacgtccg ctctcatcga tgatttgaac agctggatct ttgtactctg ccttcacacg
     2881 acggtccaat tcttcgatga ttggtaccaa gtgaggaacc acttcttgca agaattcaag
     2941 aggccatttt tcaagcgctt cagcaaggat tgtgtggtta gtgtaggcag tcatgctacg
     3001 aacaattgag attgcttcgt caagctcgat accacgtgca gttaaaagac gaatcaattc
     3061 aggaatcacc attgatgggt gagtatcgtt gatttggaca actgcgtagt cagcaaggtc
     3121 atgcaagttg cttccttttt cgattgcttc gtcgatgatc aattgcgcac cgtttgaaac
     3181 catgaagtat tgttggaaga tacggagcaa ttcaccttga cggtcactat catctgggta
     3241 aaggaagaga gtcaagttgc gagcgatatc tgtcttgtca aagttgatac catctttaat
     3301 aatagaagaa tcaactgaat ccaagtcaaa caaacgcaag cggtttttag tcgctgtttc
     3361 ataaccagta acatcaatat cgtaaagagt tgatgtcaaa gtaaagtctg caaatggtac
     3421 ttggtagcta cggcttgagc gaaccaacca gttttgctct gtcaaccatg catttggaat
     3481 tgtttcttgt tggttgtttt taagaacttg ttggaaaaga ccaaagtggt agttaagacc
     3541 aacaccgtca ccattcaaac caagagtagc aattgagtcg ataaagcagg cagccaaacg
     3601 tcccaaacca ccattaccaa gagatggttc caattcaact tcttcaactt cgatcaagtc
     3661 tttacctgca gctgcaagtt cttttttaac atcgtcgtaa agaccaaggt taatcaagtt
     3721 gtttgacaag agtttaccaa tcaagaactc agctgagatg tagtaaactt ttttcttacc
     3781 agtgttgact ggtttttggc tgcttgcaag cttgctgtag ttaagaagag caaggtaaag
     3841 ctcttcattg ctacattctg caatggtttt attgtaacga ttttgtacaa attcttgtag
     3901 tgataacatg tttagttgtc tcctgattat tgtcttattt ctttaaatct accaaatttt
     3961 cattaattcg gcgataaatt gttgtcaagt caagcaaacc ttcctcgaca gctggtgtca
     4021 attgatcttc agtcatacgc caagaccagt ttccaccaag ggtagatggg aagttcatac
     4081 gagctgcctc atccaattct agtaaatctt gcatagttgc aattgccata aagctaactg
     4141 atgaaaatac tgtacgaagc atagcgtgta ccactgtttc gtattcttta cggttcgtgt
     4201 aacgagccat gtactcacga gtcgcatcat caatctcatt acggtaccaa ccaagaaccg
     4261 tattgttatc gtgtgttcct gtgtacataa ctgagttagc aggtgccaag tgtgggctat
     4321 caatgctttc gtcttctggg ttgaaggcaa attgaagaat cttcattcct gggaagccag
     4381 tacgttcacg caattcgatc acttcatctg tcatgaagcc aaggtcttct gcgatgatgt
     4441 ttagctcacc aagttcttcc ttaacggctg caaaaagctt gtagcctgga cctttcaccc
     4501 actcaccagg tgctgctgta tcggaaccag cagggatttc ccagtaagat tcgaagccac
     4561 ggaagtggtc gatacgaacg atatcgtaga ttttgaagct ttcacgcaag cgttcaatcc
     4621 accatttgta accgtctttg tccattgctt cccagtcata gattgggtta ccccaaagct
     4681 gaccagttac agaaaactca tctggtgggc atcctgcgat acaagtagcc ttaccattga
     4741 catctgtttt gaagagatgt ggatttgccc acatatcact tgaatcttcc gctacgtaga
     4801 ttggcatgtc cccaacgatt tcgatgtggt tgtcgttagc gtaagctttc aatttcaacc
     4861 attgttggaa gaagaagtat tgagtcacac ggtggtaaac caacttgtct gccaattgct
     4921 cacgatagct ttcaagtgct gaagctttac gagcacgagc atctgcatct ggccattcag
     4981 tccaagcaag attgtcaaaa tactctttga tagccatata ctcagcaaag agctcaagcc
     5041 atgattggtt gtcttgagca aatttctcaa aatctttaac atctccgact tcaaagaaac
     5101 gtttcaccgc tttttctaaa agaggacgac gtgcatagta gattttagca tagtcaactt
     5161 cagacgcatc gctaccaaag tcaactcctt caaggtcact tgcttccaac aaaccttgct
     5221 ccaccaagat atctaaatcg ataaaatgag tgtttcctgc gaaggctgag aaagattggt
     5281 aaggagaatc cccgtaacta gttgctccta atggaaggat ttgccagtaa cgttgttttg
     5341 tacggaccaa gaaatcaacg aagtcgtaag cactttgacc aaatgatccg attccgtaag
     5401 ctcctggaag agaagagatg tgcatcaaca caccactttg acgttttttc ataatagcac
     5461 ctcgtgtgtt aaaataatgg aacgttgcgt atttttcaga cgcaaacgtt tgcgttactt
     5521 ataagtatac tccttttcaa gcataattgc aagcgttttt aaaaaacttt tttgattatt
     5581 tttaaggaga ctaactcatt ttagcaaaga taacttaaaa ctatctaatc ctaaagtttg
     5641 actctcacga gacagtctac aaagtacaaa acctccttag ggagcttgaa tttatatgca
     5701 ataaagcaca aacgtctata gaaaatagat atagattaga aacagggagg tagcccctcc
     5761 tgatttccct ctttagacag attccatata tttttattaa aaatactgta ttcttatcta
     5821 tttcatactt ttcttctatt aaaatgcaaa attatgctat caaatcaagc ttaaaaattt
     5881 tttaaaattt ttacaaaaaa tacttgcaac cgttttctat ttgtgctata ctaagctcat
     5941 aaaggaaaac gtttgcgttt ccttatcaat aaaacttgct attctttagg aggaatacac
     6001 tatgtcatct aaatttatga agagcgctgc ggtgcttgga actgctacac ttgctagctt
     6061 gctcttagta gcttgcggaa gcaaaactgc tgataagcct gctgattctg gttcatctga
     6121 agtcaaagaa ctcactgtat atgtagacga gggatataag agctatattg aagaggttgc
     6181 taaagcttat gaaaaagaag ctggagtaaa agtcactctt aaaactggtg atgctctagg
     6241 aggtcttgat aaactttctc ttgacaacca atctggtaat gtccctgatg ttatgatggc
     6301 tccatacgac cgtgtaggta gccttggttc tgacggacaa ctttcagaag tgaaattgag
     6361 cgatggtgct aaaacagacg acacaactaa atctcttgta acagctgcta atggtaaagt
     6421 ttacggtgct cctgccgtta tcgagtcact tgttatgtac tacaacaaag acttggtgaa
     6481 agatgctcca aaaacatttg ctgacttgga aaaccttgct aaagatagca aatacgcatt
     6541 cgctggtgaa gatggtaaaa ctactgcctt cctagctgac tggacaaact tctactatac
     6601 atatggactt cttgccggta acggtgctta cgtctttggc caaaacggta aagacgctaa
     6661 agacatcggt cttgcaaacg acggttctat cgtaggtatc aactacgcta aatcttggta
     6721 cgaaaaatgg cctaaaggta tgcaagatac agaaggtgct ggaaacttaa tccaaactca
     6781 attccaagaa ggtaaaacag ctgctatcat cgacggacct tggaaagctc aagcctttaa
     6841 agatgctaaa gtaaactacg gagttgcaac tatcccaact cttccaaatg gaaaagaata
     6901 tgctgcattc ggtggtggta aagcttgggt cattcctcaa gccgttaaga accttgaagc
     6961 ttctcaaaaa tttgtagact tccttgttgc aactgaacaa caaaaagtat tatatgataa
     7021 gactaacgaa atcccagcta atactgaggc tcgttcatac gctgaaggta aaaacgatga
     7081 gttgacaaca gctgttatca aacagttcaa gaacactcaa ccactgccaa acatctctca
     7141 aatgtctgca gtttgggatc cagcgaaaaa tatgctcttt gatgctgtaa gtggtcaaaa
     7201 agatgctaaa acagctgcta acgatgctgt aacattgatc aaagaaacaa tcaaacaaaa
     7261 atttggtgaa taaaaaattt gttcaagggg ggtggaaatc aaatccccct ttgaatttat
     7321 caatagagac acaaataatt tagctttctt ataaaaaagt agtatcctat gaaaggagtt
     7381 aatatggaaa agcaacaacc tagtaaagca gccctgctgt ctatcattcc tgggttagga
     7441 cagatttaca ataaacaaaa agccaaaggt tttatcttcc ttggtgtaac catcgtattt
     7501 gtcctttact tcctagcact tgcaacccct gaattgagca acctcatcac tcttggtgac
     7561 aaaccaggtc gtgataattc cctctttatg ctgattcgtg gtgccttcca tctaatcttt
     7621 gtaatcgttt atgtactctt ttatttctca aatatcaaag atgcacatac gattgcaaaa
     7681 cgcattaaca atggaattcc agttccacgc acactcaaag acatgatcaa agggatttat
     7741 gaaaatggct tcccttacct cttgatcatt ccatcttatg ttgccatgac cttcgcgatt
     7801 atcttcccag ttatcgtaac cttgatgatc gcctttacca actacgactt ccaacacttg
     7861 ccaccaaaca agttgttgga ctgggttggt ttgaccaact ttacaaacat ttggagcttg
     7921 agtaccttcc gttctgcctt tggttctgtt ctttcttgga ctatcatttg ggctttggca
     7981 gcttctactt tacaaatcgt aattggtatc ttcacagcta tcattgccaa ccaaccattt
     8041 atcaaaggaa aacgtatctt tggtgttatt ttccttcttc cttgggctgt cccagccttc
     8101 atcactatct tgacattctc aaacatgttt aacgatagtg tcggtgctat caacactcaa
     8161 gtattgccaa tcttggctaa attccttcct ttccttgatg gagctcttat tccttggaaa
     8221 acagacccaa cttggactaa gattgccttg attatgatgc aaggttggct cggattccca
     8281 tacatctacg ttttgacttt gggtatcttg caatctattc ctaacgacct ttacgaagca
     8341 gcttatattg acggtgccaa cgcttggcaa aaattccgca acatcacttt cccaatgatt
     8401 ttggctgttg cggcacctac tttgattagc caatacacct tcaactttaa caacttctct
     8461 atcatgtacc tcttcaatgg tggaggacct ggtagtgtcg gaggtggagc tggttcaacc
     8521 gatatcttga tctcatggat ctaccgtttg acaacaggta catctcctca atactcaatg
     8581 gcggcagctg ttaccttgat tatctctatc attgtcatct caatctctat gatcgcattc
     8641 aagaaactac acgcatttga tatggaggac gtctaagatg aataactcaa ttaaactcaa
     8701 acgtagactg actcaaagcc ttacttacct ttacctgatt ggtctatcaa ttgtaattat
     8761 ctatccactg ttgattacca ttatgtcagc ctttaaagca ggtaacgtct cagcctttaa
     8821 actagatact aatatcgacc tcaattttga taactttaaa ggcctcttca ctgaaacctt
     8881 gtacggtact tggtacctca acactttgat tatcgcctta attaccatgg ctgttcaaac
     8941 aagtatcatc gtacttgctg gttatgctta cagccgttac aacttcttgg ctcgtaaaca
     9001 aagtttggtc ttcttcttga tcatccaaat ggtgccaact atggccgctt tgacagcctt
     9061 cttcgttatg gcgcttatgt tgaacgccct taaccacaac tggttcctca tcttcctcta
     9121 cgttggtggt ggtatcccga tgaatgcttg gctcatgaaa ggctacttcg atacagtgcc
     9181 aatgtcttta gacgaatctg caaaactaga cggtgcagga cacttccgcc gcttctggca
     9241 aattgttcta ccacttgttc gcccaatggt tgccgtacaa gctctctggg ccttcatggg
     9301 acctttcggg gactacatcc tctctagttt cttgcttcgt gagaaagaat actttactgt
     9361 tgccgtaggt ctccaaacct tcgttaacaa tgcgaaaaac ttgaagattg cctacttctc
     9421 agcaggtgct atcctcatcg cccttccaat ctgtattctc ttcttcttcc tacaaaagaa
     9481 ctttgtttca ggacttacaa gtggtggcga caagggataa tttatccccg ccaccctttt
     9541 tcattttata ctcttcgaaa atctcttcaa accacgtcag ctttagctcc aacctcaaag
     9601 ttgtgctttg agcaacctgt ggctagtttg cactttgatt ttcattgatt attagcaatt
     9661 gtcactgtaa ataatatcct tgtagcaagc aatttttctc ctagacttga aataaagcgc
     9721 atttctctat ataataatac tcatatagaa aacacctttt agaaagatac ctatgcttcc
     9781 atatccattt tcctattttt caagtatttg ggggtttcgt aagcccctgt ccaaacgttt
     9841 cgagctcaac tggtttcaac ttctctttac cagtatcttc cttatcagct tgtctatggt
     9901 acccattgct atccaaaaca gctcccagga gacctatccg ctagaaactt ttatcgataa
     9961 tgtctatgaa cctctgacag ataaggttgt ccaggatctc tctgaacatg ctacaattgt
    10021 cgatggcaca ttaacttata ctggaacagc tagtcaagcc ccttctgttg tgattggtcc
    10081 aagtcaaatc aaggaattac ctaaggactt gcaactgcat ttcgatacaa atgagctagt
    10141 catcagcaag gaaagcaagg aactgacccg catctcttac cgagccattc agactgagag
    10201 tttcaaaagc aaagacagct tgacccaagc aatttctaaa gactggtacc aacaaaatcg
    10261 tgtctatatc agcctcttcc tagttctcgg tgcgagcttc ctctttggtt tgaatttctt
    10321 tatcgtctct ctaggagcta gtcttctcct ttatatcact aagaaatcac gcctcttttc
    10381 atttagaacc tttaaagagt gctatcactt tatcttgaac tgtttaggat tgccgactct
    10441 gattacactt attttgggat tatttggcca aaatatgaca accctgatta ctgtacaaaa
    10501 tattcttttt gttctgtatc tggtcactat cttttataaa acacatttcc gtgatccaaa
    10561 ttaccataaa taggagattt ttatgcccgt tacgattaaa gacgtggcca aggctgctgg
    10621 tgtttcgcct tcaaccgtaa cccgtgttat tcaaaataaa tcaaccatta gcgacgaaac
    10681 aaaaaaacgc gttcgcaaag ctatgaagga actcaactac cacccaaacc tcaacgctcg
    10741 tagcttggta agcagctata ctcaggttat cggattagtt cttcctgatg actcagacgc
    10801 cttctaccag aatcctttct ttccatcggt tctacgtggc atctctcaag tcgcatctga
    10861 aaaccactat gccattcaga tagcaacagg gaaagatgag aaggagcgtc tcaacgctat
    10921 ttcacaaatg gtctacggca agcgtgtaga tgggctaatc tttctctatg cccaagaaga
    10981 agaccctctc gtaaaactcg tcgcagaaga acagttcccc ttccttatcc taggtaaatc
    11041 tctatctcct ttcatcccac ttgtcgacaa cgacaatgtt caagctggtt ttgatgcgac
    11101 tgaatatttc atcaaaaaag gctgcaaacg cattgccttt atcggaggaa gtaaaaagct
    11161 cttcgtgacc aaagaccgtt taacaggcta tgaacaggcg cttaaacatt acaaacttac
    11221 cactgacaac aatcgcatct actttgccga cgagtttctg gaagaaaagg gctataaatt
    11281 tagcaagcga ttattcaagc acgatccaca aattgacgct atcatcacaa ccgatagcct
    11341 cctagctgaa ggtgtttgta actatattgc caaacaccag ctggatgtcc ctgttctcag
    11401 ctttgactcg gttaatccca agctcaactt ggcagcctat gtcgatatca atagtttaga
    11461 gcttggtcgt gtttcccttg aaactattct ccagattatt aatgataata aaaacaataa
    11521 acaaatttgt taccgtcaat tgatcgccca caaaattatc gaaaaataag agactgggca
    11581 aagagtcgtt aaaagcaaaa acgcatacta tcaggtattg aaaaaacttg atactatgcg
    11641 ttttattgtg ggaagattta cttccttttc tactgaaatt gagtcttttc ccaagatctt
    11701 tttatactca atgaaaatca aag
//
LOCUS       DAVLMQ010000053        11708 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000053 DAVLMQ010000000
VERSION     DAVLMQ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.053"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            99..752
                     /locus_tag="VXF95_001759"
     CDS             99..752
                     /locus_tag="VXF95_001759"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HEV1082268.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTAWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            762..1226
                     /locus_tag="VXF95_001760"
     CDS             762..1226
                     /locus_tag="VXF95_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1082269.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAVREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            1239..2507
                     /locus_tag="VXF95_001761"
     CDS             1239..2507
                     /locus_tag="VXF95_001761"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HEV1082270.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAVGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALLLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKVPSGMTGLETSLSLG
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            2521..2781
                     /locus_tag="VXF95_001762"
     CDS             2521..2781
                     /locus_tag="VXF95_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082271.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            2792..4153
                     /gene="pdrM"
                     /locus_tag="VXF95_001763"
     CDS             2792..4153
                     /gene="pdrM"
                     /locus_tag="VXF95_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HEV1082272.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAVFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTARFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            4307..5275
                     /locus_tag="VXF95_001764"
     CDS             4307..5275
                     /locus_tag="VXF95_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HEV1082273.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            5291..6283
                     /locus_tag="VXF95_001765"
     CDS             5291..6283
                     /locus_tag="VXF95_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HEV1082274.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFDPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDNNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKNAIRKTYNKE"
     gene            6501..7544
                     /locus_tag="VXF95_001766"
     CDS             6501..7544
                     /locus_tag="VXF95_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HEV1082275.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDIIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            7608..9293
                     /gene="lpdA"
                     /locus_tag="VXF95_001767"
     CDS             7608..9293
                     /gene="lpdA"
                     /locus_tag="VXF95_001767"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HEV1082276.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EENGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASPVPVASTSNDDGKS
                     DDAFDIVVIGGGPAGYVAAIKAAQLGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVSGMESSLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDRIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVAAENALKGNHAVAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIADKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            9357..10346
                     /locus_tag="VXF95_001768"
     CDS             9357..10346
                     /locus_tag="VXF95_001768"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HEV1082277.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINHIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDALRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(10419..11489)
                     /gene="xerS"
                     /locus_tag="VXF95_001769"
     CDS             complement(10419..11489)
                     /gene="xerS"
                     /locus_tag="VXF95_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HEV1082278.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETEGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
BASE COUNT         3472 a         2194 c         2638 g         3404 t
ORIGIN      
        1 atatagtcga tttattaaat ctttagataa attgtaaaaa gtggtttcca tagccacttt
       61 ttgctataat agaggcagta aaaatgaagg agtcagctat ggaacactcg tcttggcatg
      121 ctttgattaa ggcgcaatta cctgagggtt atttcgggaa aatcaatcag tttatggagc
      181 aggtctattc tcaggggatt atttatccac ccaaggaaaa ggtttttcag gctctcttga
      241 caacactgct tgaagaagtt aaggtggtaa ttctagggca agacccctat cacggaccag
      301 gtcaagcgca gggcttgagt ttttctgtac ctgactctat cccagctcca ccatccttgc
      361 aaaatatctt gaaagaattg tcagatgata tcggagttaa gaaatctcat gatttgacag
      421 cttgggctga gcaaggagtc ttgcttctta atgcttgttt gactgttcct gctggacagg
      481 ccaatggtca tgctggtcaa atctgggagc cttttactga tgctgtgatt caggtggtca
      541 atcatctaga tagaccagtc gtttttgtac tctggggagc ttatgcacgt aagaagaagg
      601 ccttagttac caatcctcat cacttgatta tcgaatcagc ccatccaagt cctttgtcgg
      661 tttatagagg attttggggt tccaagccct tttccaaggc caatgcattc ttaaaagaga
      721 caggacaaga gccaatcgat tggcttagat aaggagaaaa tatgcctcag ttagcgacga
      781 tttgctacat tgataatggg aaagaactgc tcatgctcca tcgtaataag aaacccaatg
      841 atgtccatga agggaaatgg attggtgtgg gtggtaagct agagagagga gagacgcccc
      901 aggaatgcgc ggtgcgtgaa atccttgaag aaacagggct caaagccaag ccagttctaa
      961 aaggtgtcat cacttttcct gaatttacac cagatttaga ctggtacacc tatgttttta
     1021 aggtgacgga gtttgagggc gacttgattg actgcaatga ggggacgcta gaatgggttc
     1081 cctatgatga ggttttgagc aagccgactt gggaaggtga ccacaccttt gttgagtggc
     1141 ttttagagga taaacccttc ttttcagcca agtttgttta tgatggggat aaattgttgg
     1201 atacccaagt tgatttctat gaataaagga gaaagcagat gctactaatc aaaaatggtc
     1261 gtgtaatgga tcctaagtct ggtttggatc aagtttgtga tgtcttagtt caagatggga
     1321 aaattatcaa aattgcgcct gagatcacgg aagaaggagc agaaacgatt gatgctactg
     1381 gtcttgtggt tgctcctggt ttggtcgata ttcatgtgca tttccgtgaa cctggtcaaa
     1441 cacataaaga agacattcat actggtgccc tagcagccgc tgcaggtggt tttactactg
     1501 tcgtcatgat ggctaatacc agtccaacca tttcagacgt ggagactttg caagcagtcc
     1561 tccagtcagc tgccaaagag aagattaatg tcaagacagt tgcgaccatt actaaaaact
     1621 ttaatggtaa aaacttgact gactttaagg cacttttaga agctggtgcg gttggtttct
     1681 ctgatgacgg tattccgctt gagagcagta agattgtcaa ggaagccatg gaggaagcca
     1741 aaaaactcaa tacctttatc agccttcatg aggaagatcc aggtttgaac ggtgttcttg
     1801 gctttaatga aaatattgct agagaacatt tccatatctg cggtgctact ggggtggctg
     1861 agtacgctat gatggcgcgt gatgtcatga ttgcctatgc aactaaagcc catgttcaca
     1921 tccagcattt gtctaaggaa gaaagtgtta aagtagtgga gtttgctcag gggttaggtg
     1981 cagaagtcac agcagaagta gcgccacagc atttctctaa gacagaagca cttcttttaa
     2041 cacaaggtag caatgctaag atgaatccac cgcttcgttt ggaatcagac cgtcgtgccg
     2101 ttatcgaagg tctcaaatca ggtgtcatca cagttattgc gactgaccac gcgcctcatc
     2161 atgtagatga aaaaaatgtt gaggatatta ccaaagtacc atctggtatg actggcttag
     2221 aaacatccct gtctctcggc ttgacctatt tagtagaagc tggtgagttg agcttgatgg
     2281 aattacttga aaaaatgaca tacaacccag ccaagcttta caactttgaa gcaggttact
     2341 tggctgagaa tggtccagca gatatcacta tttttgatgc caaggctgac cgccttgtgg
     2401 actcccattt tgcttccaaa gcagctaatt caccattcat cggtgaaacc ttaaaagggc
     2461 aggttaaata taccatctgt aagggacaaa tcgtctatca agcttgatag gagttagaat
     2521 atgaattatt ttcgaaaacg tagggagaga caagcgaaat ctaatagtgg aatttactgt
     2581 cccgcagcta atcgttccaa aattcaatat gaaactaaag aaaaagctga ccatgcggtt
     2641 caatatgata acggaggttt agttagaagc tattattgtc gtacatgtgc gtgttggcat
     2701 actacttcaa aatctaataa acctccgcta agtttgaaaa actatggtct gaaactcttt
     2761 ggtttagata aatcagaata gaaagagaag tatgtataag acaaagtgtt tacgagagaa
     2821 gttagtatta tttttaaaaa ttttcttccc aatcctgatc taccaatttg ccaattattc
     2881 tgcctctttt gttgatactg caatgacagg tcaatacaac actatggact tggctggtgt
     2941 atctatggca accagtatct ggaatccttt ctttacattt ctaacaggga ttgtgtcagc
     3001 cttggtgcct atcattggtc accatcttgg tcgaggcaaa aaggaagaag ttgcgtctga
     3061 tttttaccaa tttatttatt tggccttggg cctatctgtg gtcttgctgg ggatggtact
     3121 tttcttggca ccaacaatct tgaatcatat tgggttagaa gcagcagtag cggcagtagc
     3181 ggttcgctat ctttggtttt tatctatcgg gattatcccc ttgttgctct ttagcgtcat
     3241 tcgttccttg ctggattcgc tgggcttgac caaactgtcc atgtacctca tgcttttgtt
     3301 actccctctc aatagcggat ttaactatct cttgatttac ggtgcctttg gtgttccaga
     3361 actgggaggg gctggtgctg gtttaggaac atccttggcc tactgggtct tgcttgggat
     3421 ttctgttctg gttttattta aacaggagaa gctcaaagcc ttacaccttg agaaacgaat
     3481 tccacttaat atggataaaa ttaaggaagg agttcgttta ggtctgccta ttgggggaac
     3541 tgtcttcgcg gaagtggctg tcttttcagt ggttggcttg attatggcta agttttcgtc
     3601 cttgattata gctagtcacc agtcagctat gaacttttca agtcttatgt acgcctttcc
     3661 tatgagtatc tcatcggcta tggctattgt cgtttcctat gaagtgggag ccaagcgatt
     3721 tgatgatgcg aaaacctata ttggtctagg aagatggact gccctcattt ttgcggcctt
     3781 caccttaacc ttcctttaca tttttagggg aaatgtggcc agtctttatg gtaacgaccc
     3841 aaaatttatc gatttgacag cgcgtttttt aacttatagt cttttcttcc agttagcaga
     3901 tacctttgcg gcgccgcttc agggaatttt gcgggggtat aaggatacag ttattccttt
     3961 ttaccttggt ttgcttggtt attggggcgt agcaatccct gtggctacgc tatttgattc
     4021 cctaacagat tttggagctt attcttactg gatcggcttg attattagtt tgattgtgag
     4081 tggggcgctc taccgttggc gtttaactgt gattatgaag agatttgaat ctttagcaaa
     4141 atccaaacgc taaaaagttt gtgaaaaaat atccttgaca agaaaatccc ttgttttcac
     4201 ggggttttct tttttatttt gtgaaatttc ttttagaaaa actttgacag tatttgccaa
     4261 aagcggtaaa atagtaaggt aagaagaaag ttagaaaggc aagaagatgt caactttaga
     4321 taaaaatctt ttgctagaaa tgttccgtaa gatggaagaa atccgtcgca tggacttaaa
     4381 aattgcacaa ttagtaaaga aagggaaagt gccaggaatg acgcactttt ctgttggtga
     4441 agaggcagct aacgtggggg ctatgttagc tctcaatcca gatgatctga ttacctcaaa
     4501 ccaccgtgga cacgggcaag ctattgctaa agggattgac ctcaacggaa tgatggctga
     4561 aatccttggt aaatacactg gaacctgtaa agggaaaggt ggatctatgc atatcgctga
     4621 ccttgatgct gggaaccttg gtgccaatgg tatcgtaggt ggtggtatgg ggatcgctgt
     4681 cggtgcagcc ctcagtcagc aaatgcaaaa taccggtaaa atcgttgtct gcttctttgg
     4741 agatggtgcg accaatgaag gtgttttcca cgaagcagtg aacatggctt ctatctggaa
     4801 cctgccagtc attttctatt gcattaacaa cggttacggt atctctgcgg atatcaagaa
     4861 aatgaccaat atagaacata tccatcaacg tagcgccgct tatggaattc ctggaatgtt
     4921 catcgaagat ggtaacaatg tcatcgatgt ctatgaagga tttcagaaag ctgtggacca
     4981 tgttcgcagt ggcaatggtc cagtcttgat tgaaagtgta acttatcgct ggctcggtca
     5041 ctcatcatct gaccctggta aatatcgtac gcgtgaagaa gtggaattgt ggaaacaaaa
     5101 agatccaatc gaaaacctcc gcaattacct tattgaaaat aacattgcaa gtgccgaaga
     5161 attggaagaa atccaagcgc aagtaaagga agcagtagaa gcttctgtta aatttgcaga
     5221 ggaaagccca ttcccaccgc ttgaatcagc ctttgaagat atttacgcag actaaggaga
     5281 aagagataaa atggaaacaa aaacaatgtc cttccgtgac accattatcc ttgctatgtc
     5341 tgaggaaatg cgtcgcgatg aaaatgtgtt cttgatggga gaagacgtcg gtgtcttcgg
     5401 aggagacttc ggtacttctg ttggaatgct tgaagaattt gatccagaac gtgtccgtga
     5461 ctgtccgatt tctgaagctg ccatctctgg agcagcagca ggagcagcca tgacaggact
     5521 tcgtccaatc gtcgatatga ccttcatgga cttctctgtt attgccatgg acaatatcgt
     5581 caaccaagct gctaaaacac gttacatgtt tggtggtaaa ggtcaggttc caatgactgt
     5641 tcgttgtgca gctggtaacg gagttggctc tgccgcccag cactcacaat ctctagagtc
     5701 ttggtttact cacattccag gacttaaggt tgtggcacct ggaacacctg cggacatgaa
     5761 aggcctgctt aagtcttcta tccgtgataa caacccagtt attatacttg agtacaagtc
     5821 agaatttaac caaaaagggg aagtgccagt tgatccagac tacacaattc cacttggggt
     5881 tggtgaaatc aaacgccaag gaacggatgt aacagttgtt acttatggaa aaatgcttcg
     5941 ccgtgtggtt caagctgctg aagaattagc agaagaagga atttcagttg aaattgttga
     6001 cccacgtacc cttgttccgc ttgataagga tatcatcata aactcagtga agaagactgg
     6061 taaggttgtt ctggtcaacg atgcccacaa aacaagtggc tatatcggtg aaatttcagc
     6121 tattatttca gaatcagaag catttgacta tctagatgca ccaattcgcc gttgtgcagg
     6181 agaagatgtg ccgatgcctt atgcacaaaa cctagaaaat gcaatgattc caacagttga
     6241 aagtatcaaa aatgcaatcc gaaaaactta taacaaagaa tagagttaca taagataagt
     6301 tatgtaaata aaataaagct gacgagaaac tttgtatctt ttaggtgcag agctcttcgt
     6361 cattaatatc ttagattaga gcacgggcta aaagctcgga aaaaagataa atctccttgg
     6421 cttcatcgaa gccatcgtcg atttcctatt tttcagtcgc ttttgacgcc ctttgtatca
     6481 taaatagaat tggagaggtc atggctgatg acaagctaag agcgactcct gcagctagaa
     6541 agttagcgga tgatttaggg ataaacctct acgacgtttc tggctcaggt gcaaacggtc
     6601 gtgtccacaa agaagacgtg gaaacttata aagacacaaa cgtggttcgc atttcgccac
     6661 ttgcaaaacg aattgccctc gaacataaca ttgcttggca ggaaatccaa ggaaccggtc
     6721 atcgtggtaa aatcatgaag aaggatgttt tggccctgct tcctgaaaat atcgaaaacg
     6781 atagcatcaa atctcctgct cagattgaaa aagtggaaga agtccctgat aacgtaacac
     6841 catatggtga aatcgagcgt attccaatga caccaatgcg taaggttatt gcccaacgca
     6901 tggttgaatc ttacttgact gcgccaacct tcaccctcaa ctatgaagtt gatatgactg
     6961 aaatgttggc tcttcgtaag aaggttcttg agccaatcat ggaagcaact gggaagaaga
     7021 ctactgtaac agaccttctt tcgcttgcag ttgttaagac tcttatgaaa cacccataca
     7081 tcaatgcttc attgacagaa gatggcaaga ctattatcac tcacaactat gtcaatcttg
     7141 ccatggcagt tgggatggat aatggattga tgacacctgt tgtttacaat gctgagaaga
     7201 tgagtctttc agaactggtt gtagccttta aggatattat tggccgtacc ttggatggta
     7261 aattggctcc aagtgagtta caaaattcaa cattcacaat cagtaatttg ggaatgtttg
     7321 gtgttcagtc ctttggcccg attattaacc aacccaactc agctatcctt ggtgtcagtt
     7381 cgacaatcga gaagccagtt gtcgtcaatg gtgaaattgt gattcgccca atcatgagtt
     7441 taggattaac cattgaccac cgtgtcgtag atggtatggc tggtgctaag tttatgaagg
     7501 acttgaaaga gttgattgaa acgccaatct caatgttaat ttaagagcaa gagtattcat
     7561 ttttaagata tagataaagg aaggaagaca tggccttaga agtaattatg ccaaaagccg
     7621 gcgtggatat gacagaagga caaatcgtcc aatggaataa aaaagtcgga gaatttgtaa
     7681 aagaaggaga aatccttttg gaaatcatga ctgataaagt cagcatggaa ttggaagccg
     7741 aagaaaatgg atacttgatt gccattctca aaggagatgg tgaaactgtc cctgtaacgg
     7801 aagttatcgg ttaccttggt gaagaaaggg aaaacatccc aacagctgga gcagcatcgc
     7861 cagaagctag ccctgtacct gtagcaagta cctcaaacga tgatggtaag agcgatgatg
     7921 cttttgatat cgttgtgatt ggtggaggtc ctgctggtta tgttgcagcc attaaagctg
     7981 cccaactcgg cggtaaggtt gcccttgttg agaaatctga acttggtgga acctgcttaa
     8041 accgtggatg tattccaacc aagacctacc ttcataacgc tgaaattatt gaaaatatcg
     8101 gtcatgctgc aaatcgtggt atcgtgattg aaaatcctaa cttcactgtt gatatggaaa
     8161 aacttttaga aactaaatct aaagttgtta atactcttgt tggtggtgtt gcaggacttc
     8221 ttcgtagcta cggagttact gttcataaag gaattggtac aatcactaaa gacaagaacg
     8281 tcttggtaaa tggttctgaa ttgcttgaaa ccaagaaaat cattcttgct ggtggttcaa
     8341 aagtcagcaa gatcaacgtc tctggtatgg aatcttcact tgtcatgact agtgatgaca
     8401 ttcttgaaat gaacgaagtg ccagaaagcc ttgttatcat cggtggtgga gttgtcggta
     8461 tcgaactcgg tcaggccttc atgacatttg gttcaaaagt gactgttatc gaaatgatgg
     8521 accgtatagt tccagctatg gatgcggaag tttctaagaa ccttcgcttg atccttgagc
     8581 gtaaaggaat gaccatcttg actggtacta aactgcaaga aatcattgag gaaaatggtc
     8641 aacttcgtat caaggttgaa ggaaaagacg atatcatcgc aagcaaagct cttctttcaa
     8701 ttggtcgtat gccagacctt gaaggtattg gagaggttga gtttgaattg gatcgtggtt
     8761 gtatcaaggt caacgaatac atggaaactt cagttccagg catttatgca ccaggtgaca
     8821 tcaacggtac taagatgttg gctcacgcag ctttccgcat gggtgaagtt gccgctgaaa
     8881 atgcccttaa aggaaatcat gcagttgcca aattgaattt gactcctgca gccatctaca
     8941 ctctccctga agtagcagca gtaggtttga cagaagaaca agcccgtgag aaatacgatg
     9001 ttgccatcgg taagtttaac tttgctgcta acggtcgtgc tattgcatct gacgcagctc
     9061 aaggtttcgt aaaagttatc gctgataaga aatacggaga aatccttggt gtacacatta
     9121 ttggtcctgc agccgcagaa ttaataaacg aagcatcaag catcatcgaa atggaaatca
     9181 ctgttgagga aatgctgaag accatccacg ggcacccaac ttactctgaa gtgatgtacg
     9241 aagcgtttgc agatgttcta ggaatggcca tccattcacc taagaaaaaa taaaacgaag
     9301 atagattaga ctggaaggtt atttccagtt tctatcatat aaagtaaagg gatatcatga
     9361 aatacattat caatcattca aatgacactg cttttaatat tgccttggaa gaatacgcct
     9421 ttaaacacct tttggatgag gatcaaatct tcctactttg gattaacaag ccatctatca
     9481 ttgttggtcg tcaccagaac actatcgaag aaatcaaccg tgattatgtt cgcgaaaatg
     9541 gtattgaggt agttcgccgt attagtggtg gtggagctgt ttaccacgat ttaaataacc
     9601 tcaactacac gatcatctcc aaagaagatg aaaataaggc atttgacttc aagagcttct
     9661 caactccggt tatcaatacc ctggctcaac tcggggttaa agctgagttc acaggtcgta
     9721 atgaccttga gattgatggt aagaagttct gtggcaatgc ccaagcctat atcaacggcc
     9781 gtatcatgca ccacggttgc ttgctctttg acgttgattt gtcagtcctc gcaaatgccc
     9841 ttaaggtttc aaaagataaa tttgaatcaa aaggtgtgaa atccgtccgt gcccgtgtaa
     9901 ctaatattat caatgaatta ccaaaaaaaa tcacagtcga aaaattccgt gatttactct
     9961 tggaatacat gaaaaaagag tacccagaga tgactgaata cgtcttttca gaagaagaat
    10021 tggccgaaat caatcacatc aaggatacta agtttggaac ttgggactgg aactatggta
    10081 aatcacctga atttaacgtc cgtcgtggaa ccaaattcac tagtggtaag gttgaagtct
    10141 ttgctaacgt tactgaatca aaaatccaag acatcaagat ttatggtgac ttctttggta
    10201 ttgaagacgt tgctgcagta gaagatgccc ttcgtggggt gaaatacgaa cgcgaagatg
    10261 ttcttaaggc gctaaaaacc attgatatca cacgctactt cgctggtatt agccgtgaag
    10321 aaatcgctga agcggtagtt ggataaatca aaaagaagtt ggccaactaa ccaacttctt
    10381 tttttgatat ttatttacat aatttaaaat acgtaaaatt ataaactatc tagagcattc
    10441 ttttgttcat cattaacaat atgggtatag aggtcagtga cttgtgtgct agcatgtcct
    10501 agttggtgac tgactaaaac ttgtgattta gttgcatcat agagcctagt tgctagtgta
    10561 tggcgcagtt tatggggtgt tacacgcact ttaaaatcct ctgagtattt agcaaccatt
    10621 ttctcaacgc tagaagcatc gatacgatta ggaacacctc tgtagagagt taaaaaaagg
    10681 gctgtatctg ttttttccgt tttatagcgt tgattccgaa tggccagata attctctaaa
    10741 taaggtttag caaaagcagc gacattgact gagtcacgtt tgccaccttt tcgagtaaca
    10801 tcaataacca tcatttttag attgagatct cttagatcta gattaacagc ttcagataag
    10861 cgaacaccag atgccaagag aagggcaata atggctaaat ctcgttcttt atttttgttg
    10921 aatgatgaga gagctcgatt tgaaagctgt tgtgggtgct cttgatcgat ataagttaga
    10981 aaaccttctg tttcatcacc tagaaagagt ttttgcttga tattttcagc tctggcagca
    11041 agggtttctt tctttttctt ggttgaaact tttttcatta cattacgata gaaataaggt
    11101 tccccctgat cgttttcaac ctcctcggtt agatatttgt aaagactaga aagtgctgat
    11161 aaggttcgat tgatagttgt ctgtgaaaca ccttgttttg ttgtattagc attcagcaag
    11221 ggacgttcac gtagataaag gataaaggat tccatgtctt tcttagacat attttccaaa
    11281 actgataaag gaatatcgga tattttatca gcgtttgaaa taccagactc caaaacccag
    11341 ctgaaaaatc ggtcatattc cttaaggtat tcgtacaggg ttgtaaaact gtagggcaca
    11401 gccagcttag attggtagta ttccagaaca taccagggca tgagttgttt tagtttgtcg
    11461 attcgttcca gtaaaatctc acgtttcatg tattttctcc ataagtaagt atactagtag
    11521 tatagcatag acttgtatat ttttcaagaa aattatagtt tttctgaaag atgttatagg
    11581 agtttttcaa agtgataaaa agacttagac ctacaaacaa aacagaataa ggaaaataat
    11641 aaaaatctca cccactaaac ttctgttaat actacataac tgaagagcta tataaggagc
    11701 tatgagat
//
LOCUS       DAVLMQ010000054        11560 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000054 DAVLMQ010000000
VERSION     DAVLMQ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11560
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.054"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            68..931
                     /locus_tag="VXF95_001770"
     CDS             68..931
                     /locus_tag="VXF95_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082279.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDNLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            1314..1934
                     /locus_tag="VXF95_001771"
     CDS             1314..1934
                     /locus_tag="VXF95_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082280.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYTGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            2020..2463
                     /gene="tsaE"
                     /locus_tag="VXF95_001772"
     CDS             2020..2463
                     /gene="tsaE"
                     /locus_tag="VXF95_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HEV1082281.1"
                     /translation="MYTKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLLEELQYGV"
     gene            2453..2971
                     /locus_tag="VXF95_001773"
     CDS             2453..2971
                     /locus_tag="VXF95_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082282.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKIAGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLID"
     gene            2979..3995
                     /locus_tag="VXF95_001774"
     CDS             2979..3995
                     /locus_tag="VXF95_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HEV1082283.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNAERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSVGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            4080..5336
                     /locus_tag="VXF95_001775"
     CDS             4080..5336
                     /locus_tag="VXF95_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HEV1082284.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGNKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFEGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            5391..6557
                     /gene="recA"
                     /locus_tag="VXF95_001776"
     CDS             5391..6557
                     /gene="recA"
                     /locus_tag="VXF95_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HEV1082285.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVPLDLGDELEIEIEE"
     gene            6864..8234
                     /locus_tag="VXF95_001777"
     CDS             6864..8234
                     /locus_tag="VXF95_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HEV1082286.1"
                     /translation="MNKKRTVDLIHGPILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPQFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWVVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSTFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            8610..9566
                     /gene="lytA"
                     /locus_tag="VXF95_001778"
     CDS             8610..9566
                     /gene="lytA"
                     /locus_tag="VXF95_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HEV1082287.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKHDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            9912..10073
                     /locus_tag="VXF95_001779"
     CDS             9912..10073
                     /locus_tag="VXF95_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082288.1"
                     /translation="MNMINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            10060..10266
                     /locus_tag="VXF95_001780"
     CDS             10060..10266
                     /locus_tag="VXF95_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082289.1"
                     /translation="MDLSNKAPNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLGR"
     gene            10312..10671
                     /locus_tag="VXF95_001781"
     CDS             10312..10671
                     /locus_tag="VXF95_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082290.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKVMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMSLG"
     gene            10800..11225
                     /locus_tag="VXF95_001782"
     CDS             10800..11225
                     /locus_tag="VXF95_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082291.1"
                     /translation="MTSRVFIDADCISVFLWVGTEHLLEKLYSGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEAASISLA
                     KKHNGILGSNNLRDVKSYVEEFSLEHMTTGDILIEAFKV"
BASE COUNT         3637 a         1869 c         2547 g         3507 t
ORIGIN      
        1 taacttacta ttttgaacta aaaattttat aatgaaatta agcaaatagg aaggtttatt
       61 atctttaatg aatacactcg cagagaaatt cagattgaaa agaaaagagt tgagactctc
      121 ccaacaaact cttgcagaag gaatttgtga acaaagtcag attagtaaaa ttgagagagg
      181 gcatttcatt ccctccgcag accttttgtt caaactctca caacgacttg aagtaccatt
      241 agattatttt tttaatgaac aaattgaaat taaatctaac ctctctaatt tcaagcaatt
      301 gtctgctcga ctattagatg acagaaatta tgataatttg gaatatattt atagaattga
      361 gattgaacga agtacttttc taacactaga agaccgaact tatcttgaat ggattaaagc
      421 tattattgac ttctatcaat atgacagtaa gtgtgaggca atttcttcat tggaaaatat
      481 attattaaaa gtctcttcaa atactctgat ttatttaaag gcgttgaata ctctatctaa
      541 tttctattcc ttagtgggtc gtgaacaaga atatgaggca aactactctc atttaataga
      601 gttgtatcag acaaaaaatt tggaccatca agagttttta tttggctaca tcagagttcg
      661 ttacaactac gctcactacc tagtatcaaa ggaaaaatat aatgaagcca tccaagaagc
      721 tcttgaaacg attgaactct gtaaacaaag acagacaagc taccaattgg ctcctctact
      781 tattcttgta ggaaatgctg gagccaaatt tctagacaga gaacaagtca aaaattatta
      841 tatagaagca agagagttat gtaagattta taacaatcct ttaatgttga tgaagataga
      901 aaattatttg aaggaattag atactgttta gttaatcttg acattatagt ttttctgaaa
      961 cgttaaataa cctgtaaggc tgatagttag attaatacta tcagccttat cattatgtga
     1021 ctctgagtcc gtctcgctcc gtgaggtgcg agacaaaaca accacccgtt tgacggattt
     1081 tcatgatttc aaatttatat tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca
     1141 atctcaaaac actgttttga gcaacctgtg gctagctacc tagtttgatc tttgattttc
     1201 attgagtatt agtctctagt gtttgtttag cgtcttaaag agacatttga gaagattaga
     1261 aacagttctc tcttttctcc tagtataatg attggtagga agggagagag aagatgaaat
     1321 caatgagaat cttatttttg ttagctttaa ttcaaatcag tttgagtagc tgtttcctat
     1381 ggaaggaatg catcttgtcc tttaaacaaa gtacagcttt tttcatcgga agcatggttt
     1441 tcgtttcagg aatctgtgct ggagtaaatt atctttatac ccgtaagcaa gaagtccata
     1501 gtgtcctagc cagtaagaag tcggtgaagc ttttttacag tatgttactc ttaattaatt
     1561 tgttaggagc tgttcttgtt ttgtcagata acttgttcat caaaaatacg ctgcagcaag
     1621 aattagttga ctttttattg ccatccttct ttttcctatt tgggctagat ttgctgattt
     1681 ttttaccctt gaaaaaatac gtgcgcgatt ttcttgctat gctagacaga aaaaagacag
     1741 tgttggtgac tattttagca acacttcttt tcttaagaaa tccaatgacc attgtctcac
     1801 ttctgattta tactggactg ggcttgtttt ttgcagccta tcttgtccca aattcggtta
     1861 agaaggaagt ttccttttat ggtcatattt tccgagatct tgtattggtc attgttacgc
     1921 tcattttctt ttagagaaag cctgtttttt atggatgtta tgatgataag tttagtagga
     1981 aaatagacac aaaagaaaag tttttggtat aataagagta tgtacacaaa aaatgaagaa
     2041 gagttgcaag ccttagggga gcgtttgggc catctattag caaagaatga tgttttaatc
     2101 ttaattggag aactgggtgc aggtaaaacg acctttacta aaggacttgc aaaaggatta
     2161 cagatttctc aaatgattaa aagtcctacc tatactatcg tgagagagta tgaaggtcga
     2221 cttccacttt atcacctaga tgtttatcgt attgaaggag atgctgattc tatcgacttg
     2281 gatgagttta tctttggtgg cggcgtgact gttattgagt ggggaaatct cttaggagat
     2341 gccttgccag atgcttattt agaattggaa attctaaaag aagcagatgg acgccgttta
     2401 aattttcagg caaagggttt gcgtgctgag aaattgttag aggagcttca atatggagta
     2461 tgaattgctc attagggaag cagagcccaa agatgcagct gaattagtgg cctttttaaa
     2521 tcgtgtgagt ttggagacag actttaccag cctagacgga gatggtattc tcttgactag
     2581 tgaggagatg gaaatattcc tcaacaagca agctagttcg gacaatcaga taaccttact
     2641 tgcattctta aatggcaaaa ttgctggtat tgtaaatatt acagctgacc agcgtaagag
     2701 agtccgtcat attggagatc tcttcattgt gattggaaaa agatattgga ataatggctt
     2761 gggaagtttg ttgctagaag aagcgataga gtgggcacaa gcaagtggca ttctgcgtcg
     2821 tctccaactg actgtccaaa ctcgtaatca agcagcagtc catctttatc aaaagcatgg
     2881 ctttgtcatt gaaggtagcc aagagcgtgg ggcatatata gaagaaggga aatttatcga
     2941 tgtttacttg atgggtaaac tgatagatta gtagaaatat ggttaaaaaa attattggaa
     3001 tggtgctagc tttactttct gtaactgtag taggagtagg tgtttttgct tatactattt
     3061 atcaacaagg gacagaaacc ttagctaaaa cctataaaaa aatcggcgaa gaaaccaagg
     3121 ttattgaagc gactgaacct ctaaccattc tgttaatggg agtggacacc ggaaatgctg
     3181 aacgaactga aacttgggtc ggtagaagtg atagcatgat cttgatgaca gtgaatccta
     3241 aaacgaaaaa aacaacaatg atgagtttag agcgggatat tctgacgcgc attgaatcag
     3301 ggaatggtca ggctcatgaa gcgaaactga actcagcata tgcagatggt ggagcagagc
     3361 ttgctataga aaccattcaa aaaatgatga atatccatat tgatcgctat gtgatggtca
     3421 atatgagagg gttgcaaaaa ctagtggatg cagtaggagg tattacagtc aataatatcc
     3481 taggtttccc aatttctatc agtgaccaag aagaatttaa tactatttct atcggtgttg
     3541 gggagcaaca tattggggga gaagaagccc tagtctatgc acgaatgcgt taccaagatc
     3601 ctgaggggga ttatggtcgt caaaaacgtc aacgtgaagt tattcaaaaa gtcatggaaa
     3661 aagctctcag tttaaatagc gttggtcatt atcaagagat tctaaaagct ttgagtgaca
     3721 atatgcagac caatattgat ttgtctgcaa aaagtatccc taacttgcta ggctataaag
     3781 attcatttaa aaccattgaa actcagcagt tgcagggtga aggagagata cttcaaggtg
     3841 tttcttacca gattgtttcg agagcacata tgttggaaat gcaaaatata ctccgacgtt
     3901 ctttgggaca agaagaagtt actcagcttg aaaccaatgc ggttttattt gaagatttat
     3961 ttggcagagc acctgttggt gatgaagata attaactttt gatacaaata aaaaaatcaa
     4021 tcgtaggaaa attcctgcga ttttttcaaa aaaatacgaa tagataggta ggaggaaaca
     4081 tgaaagcaga aatcattgct gttggaacag agattttgac aggacagatt gtcaacacca
     4141 atgcccagtt tttgtcggaa aaactagctg agattggggt agatgtatat tttcagacgg
     4201 ctgtaggaga caatgaagtt cgtctcttgt ctttgcttga gattgccagt caacgtagca
     4261 gtctggtgat tttgacaggc ggtttggggc caactgagga cgacctaacc aaacaaaccc
     4321 tagctaaatt tttagggaaa gcattagtct ttgatcctca ggctcaggag aagttggata
     4381 tcttttttgc cctgcgacca gactatgccc gaacaccgaa taacgaaaga caagctcaaa
     4441 ttgtagaagg agcgattcca ctgccaaacg aaacaggact ggctgttgga ggaaaattag
     4501 aagtagacgg agtgacctat gtcgtccttc caggtccgcc aagtgaattg aaacccatgg
     4561 tcttaaacca acttctaccc aagttgatga cagggaacaa gctgtattcc cgagttcttc
     4621 gtttctttgg gattggcgag agccagttgg ttacgatttt ggctgattta attgataatc
     4681 agatcgatcc taccttggcc ccttatgcca agacaggaga agtcactcta cgtctgtcaa
     4741 caaaggctag cagtcaagaa gaggcgaatc aagcgctgga tatcttggaa aatcaaatct
     4801 tggactgcca gactttcgaa ggaatttctt tacgagactt ttgctatggt tatggggaag
     4861 aaactagttt agccagcatt gtggtagaag aactgaaaag gcaagggaaa accatcgcgg
     4921 ctgcagagag tttgacggca ggtcttttcc aagctaccgt ggcgaatttt tctggagttt
     4981 caagtatatt tgagggtggt tttgtgacct atagcttgga ggaaaaatca aggatgttgg
     5041 atattcctgc caagaatttg gaagaacatg gtgtggtgtc tgaatttaca gctcagaaga
     5101 tggctgagca ggcacgaagc aagacccagt ctgattttgg aattagtttg actggagtgg
     5161 caggaccaga tagcctagaa ggacacccag ttgggacagt cttcataggc ttggcgcaag
     5221 atcaaggaac tgaggttatc aaggttaata ttggaggcag aagccgagca gatgtacgtc
     5281 acattgcggt tatgcatgcc tttaacctag ttcgcaaggc tttattaagt gactaacttt
     5341 tgatataata gtagataggt ctgaggatca ttagaatgta ggagaataga atggcgaaaa
     5401 aaccaaaaaa attagaagaa atttcaaaaa aatttggggc agaacgtgaa aaggccttga
     5461 atgacgctct taaattgatt gagaaagact ttggtaaagg atcaatcatg cgtttgggtg
     5521 aacgtgcgga gcaaaaggtg caagtgatga gctcaggttc tttagctctt gacattgccc
     5581 ttggctcagg tggttatcct aagggacgta tcatcgaaat ctatggccca gagtcatctg
     5641 gtaagacaac ggttgccctt catgcagttg cacaagcgca aaaagaaggt gggattgctg
     5701 cctttatcga tgcggaacat gcccttgatc cagcttatgc tgcggccctt ggtgtcaata
     5761 ttgacgaatt gctcttgtct caaccagact caggagagca aggtcttgag attgcgggaa
     5821 aattgattga ctcaggtgca gttgatcttg tcgtagtcga ctcagttgct gcccttgttc
     5881 ctcgtgcgga aattgatgga gatatcggag atagccatgt tggtttgcag gctcgtatga
     5941 tgagccaggc catgcgtaaa cttggcgcct ctatcaataa aaccaaaaca attgccattt
     6001 ttatcaacca attgcgtgaa aaagttggag tgatgtttgg aaatccagaa acaacaccgg
     6061 gcggacgtgc tttgaaattc tatgcttcag tccgcttgga tgttcgtggt aatacacaaa
     6121 ttaagggaac tggtgatcaa aaagaaacca atgtcggtaa agaaactaag attaaggttg
     6181 taaaaaataa ggtagctcca ccgtttaagg aagccgtagt tgaaattatg tacggagaag
     6241 gaatttctaa gactggtgag cttttgaaga ttgcaagcga tttggatatt atcaaaaaag
     6301 caggggcttg gtattcttac aaagatgaaa aaattgggca aggttctgag aatgctaaga
     6361 aatacttggc agagcaccca gaaatctttg atgaaattga taagcaagtc cgttctaaat
     6421 ttggcttgat tgatggagaa gaagtttcag aacaagatac tgaaaacaaa aaagatgagc
     6481 caaagaaaga agaagcagtg aatgaagaag ttccgcttga cttaggcgat gaacttgaaa
     6541 tcgaaattga agaataagct gttaaagcag tggagaaatc cgctactttt tcgatttttg
     6601 attcaagttt ttagattata tatagtagct tgaaataaga tatgaacaac tttattagga
     6661 aagtcaaatt aatttctaga aatgttttag cagctacagc gtactattcc aaactcaacc
     6721 aactataata gatcgaaact agaatagtac acatctactt ctaaaacatt gttaaaaatc
     6781 gatttgactg tccttatttc attccgctat atataagttt gctgtttctt gtcgctcctc
     6841 tggaaagctg atataatagc tttatgaata aaaaacgaac agtggacctg atacatggtc
     6901 cgattcttcc ctcgctctta agcttcacct ttccaatctt gctatcaaat atttttcaac
     6961 agctctataa cactgctgat gtcttgattg ttggacgatt tcttggtcaa gaatccttgg
     7021 ctgcagtagg agcgacgaca gcgatttttg acctgattgt aggctttaca cttggtgttg
     7081 gcaatggcat ggggattgtc attgctcgtt attatggggc tcggaatttc actaaaatca
     7141 aggaagcagt agcagccacc tggattttag gtgctctttt gagcattcta gttatgttgc
     7201 tgggctttct tggcttgtat cctctcttgc aatacttaga tactcctgca gaaattcttc
     7261 ctcaatctta tcaatatatt tctatgattg tgacctgtgt aggtgtcagc tttgcttata
     7321 atctttttgc aggcttgttg cggtctattg gtgacagtct agcagccctg ggatttctga
     7381 ttttctctgc cttggttaat gtggttctgg atctctattt tattacgcaa ttgcatctgg
     7441 gagttcaatc cgcaggactt gctaccatta tttcgcaagg tttatcagcg gttctctgct
     7501 tttattatat tcgtaaaagt gtgccagaac tcttgccaca gtttaaacat ttcaaatggg
     7561 acaaaagctt gtacgcggat ctcttggagc aaggtttggc tatgggcttg atgagttcaa
     7621 ttgtatctat cggcagtgtg attttacagt tttctgttaa tacatttggt gcagtgatta
     7681 ttagtgccca gacggcagct cgacgcatta tgacctttgc ccttcttcct atgaccgcta
     7741 tttctgcatc aatgacgacc tttgcttctc agaatctagg agctaagcga cctgaccgta
     7801 ttgttcaagg tcttcgaatc ggcagtcgtt taagtatatc ctgggtagtt tttgtttgta
     7861 ttttcctctt ttttgccagt ccagctttgg tttccttctt ggctagttcg acagatggtt
     7921 acttgataga aaatggaagt ctctatctgc aaatcagttc aaccttttat cccattttga
     7981 gcctcttgtt gatttatcgc aattgcttgc agggcttggg gcaaaagatc cttcctctag
     8041 tttctagctt tattgaacta atcggaaaaa tcgtttttgt ggttttgatt attccttggg
     8101 caggatataa gggtgttatc ctttgtgaac ctcttatctg ggttgccatg acagttcaac
     8161 tgtacttctc attattccgt catcccttga taaaagaagg caaggcaatc ttggcaacca
     8221 aagtgcaatc ctagttggat ttactgaata aaatccattt cctctagtga aaatcgaaaa
     8281 aacttgtgtt ctcgtcttta gtttggtgtt gaaaatagtt taacagactt ttgacttctt
     8341 ttatatgata taataaagta tagtatttat gaaaaggaca tatagagact gtaaaaatat
     8401 acttttgaaa agctttttag tctggggtgt tattgtagat agaatgcaga ccttgtcagt
     8461 cctatttaca gtgtcaaaat agtgcgtttt gaagttctat ctacaagcct aatcgtgact
     8521 aagattgtct tctttgtaag gtagaaataa aggagtttct ggttctggat tgtaaaaaat
     8581 gagttgtttt aattgataag gagtagaata tggaaattaa tgtgagtaaa ttaagaacag
     8641 atttgcctca agtcggcgtg caaccatata ggcaagtaca cgcacactca actgggaatc
     8701 cgcattcaac cgtacagaat gaagcggatt atcactggcg gaaagaccca gaattaggtt
     8761 ttttctcgca cattgttggg aacggttgca tcatgcaggt aggacctgtt gataatggtg
     8821 cctgggacgt tgggggcggt tggaatgctg agacctatgc agcggttgaa ctgattgaaa
     8881 gccattcaac taaagaagag ttcatgacgg actaccgcct ttatatcgaa ctcttacgca
     8941 atctagcaga tgaagcaggt ttgccgaaaa cgcttgatac agggagttta gctggaatta
     9001 aaacgcacga gtattgcacg aataaccaac caaacaacca ctcagaccat gtggatccat
     9061 acccttactt ggcaaaatgg ggcattagcc gtgagcagtt taagcatgat attgagaacg
     9121 gcttgacgat tgaaacaggc tggcagaaga atgacactgg ctactggtac gtacattcag
     9181 acggctctta tccaaaagac aagtttgaga aaatcaatgg cacttggtac tactttgaca
     9241 gttcaggcta tatgcttgca gaccgctgga ggaagcacac agacggcaac tggtactggt
     9301 tcgacaactc aggcgaaatg gctacaggct ggaagaaaat cgctgataag tggtactatt
     9361 tcaacgaaga aggtgccatg aagacaggct gggtcaagta caaggacact tggtactact
     9421 tagacgctaa agaaggcgcc atggtatcaa atgcctttat ccagtcagcg gacggaacag
     9481 gctggtacta cctcaaacca gacggaacac tggcagacaa gccagaattc acagtagagc
     9541 cagatggctt gattacagta aaataataat ggaatatctt tcaaatcaga acagcgcata
     9601 ttattaggtc ttgaaaaagc ttaatagtat gcgttttctt gtggagatat ttccttcaat
     9661 ttttgctact atattaaaca aaaatcaaaa agcaaactag aaagttatgc tcaaataaaa
     9721 tctaaatttg acaatgtaaa ccgagtcgga tagctttaag tactgttttg aggttgaaga
     9781 tacgattttt gataggaact catcaatttt agatttttaa gcagcatcaa taaattgctt
     9841 ccttgttttg tcataatttt tttatttaaa aaattatgac aagagtgtgc tattcttttt
     9901 atgagaggtg tatgaatatg ataaatgtat gtgatgttgg aaaaagaata aaagaactta
     9961 gaatatcttc aaatcttact caagataaga ttgctgagta tttgtctttg aatcaaagca
    10021 tgattgccaa aatggaaaaa ggtgaaagga atatcacgaa tggatttaag taataaagct
    10081 ccaaatctta gaaaaaagtt gggagctgat ggtgaatcgc cgatagatat ttttaaattg
    10141 gtacaaaaga tagaaaattt gacgctggta ttttatggac tcggaaagaa tattagcgga
    10201 gtctgttata aaggaactca gttcagtctc attgcagtca attcagatat gccattagga
    10261 aggtaaagat tttctttagc acatggactg tatcatcttt attatgatga ggtgaagaag
    10321 agttcagtca gtcttatctt gattggtgaa ggagatgaaa ctgaaagaaa agcggatcag
    10381 tttgcttctt attttttaat tttcccatct tcactgtata ggatggttga ggaaatcaga
    10441 gaaaatgcca atagaactca tcttgaagta gaagatatta taaaattggg tcagttttat
    10501 ggtatcagtc ataaagttat gttatataga ttgaggaatg atggatacct tgatgcagaa
    10561 gaaattaaaa atatggatat tagtgttata gagacagctt caagattagg ctatgataca
    10621 agtttatatc gtcctttgtc agaaagtaaa aaggaaatgt cattaggata atatattaat
    10681 tcaactgaac aacttttaga aaataacaga atttcgcaag ggaagtatga ggaactgtta
    10741 ctagatgctt tcagatatga tattgtatat gggctagatg aagagggggg agttgtcgtt
    10801 tgactagtcg tgtatttatt gatgcagatt gtatttcagt atttttatgg gttggcactg
    10861 aacatctttt agaaaagctc tattcgggta aaattgttat tccacaagag gtgtatgatg
    10921 aaatcaatat acctacaatt ccccatttaa aatctaggat agaccagttg gtagctaagg
    10981 gttcagctga gattgtgagc atagacattg gaactgaaga atacgcatta tatagagatt
    11041 taacaagaaa tcatgatagt aacaagatta ttggtaaggg agaagcggct tctatttcct
    11101 tagcgaaaaa gcataatggg atattaggaa gtaataacct aagagatgtt aaatcatatg
    11161 tagaagaatt ttctttagaa catatgacaa caggagatat actgattgaa gcgtttaaag
    11221 tgtaatttat tactgaacaa gagggcaatc atatctggaa taatatgctt aaaaagagaa
    11281 ggaaaattgg tgcaaattca ttttcagact atcttcgtgg aagtattcat caaaatagac
    11341 aaaaataaat ttggataaat cgaactcact attcaggagg catatgagca attcgaaaaa
    11401 gaaaagtgtc aaattgagcc tataggagta gaagtgaaat agtaagtcct gcatagtgga
    11461 tgagagaaaa gttctccttg aagttttcct gaactatcag tcgcatgtca aacgatatgt
    11521 agggtaatgt gagaggggat agcgagtagt ttttggttat
//
LOCUS       DAVLMQ010000055        11532 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000055 DAVLMQ010000000
VERSION     DAVLMQ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.055"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(98..268)
                     /locus_tag="VXF95_001783"
                     /pseudo
     CDS             complement(98..268)
                     /locus_tag="VXF95_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
     gene            complement(411..1010)
                     /locus_tag="VXF95_001784"
     CDS             complement(411..1010)
                     /locus_tag="VXF95_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082292.1"
                     /translation="MQILCYFTITVVAKPNNSGEVHLDVSIEDNQGGSGYNFSSVSSS
                     SQTAKYEGTGYNNNSSLYITIDKTSDATALLKLKLNNVDNQPATEVPSSGITVKLNAK
                     DNAGNWTSASNKKEVTVKIVSAKPTYPDKILVKNPDNIKDTEKNAIIEKLKEANKNHP
                     AGAPTFAKGEGEHANDIVATYSDGTTYYVPLNDVTKYAR"
     gene            complement(1147..2031)
                     /locus_tag="VXF95_001785"
     CDS             complement(1147..2031)
                     /locus_tag="VXF95_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HEV1082293.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLTSW
                     LDMMRTLFPNCQTVLQVGAQDYVFVLQQDKYTSVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            complement(2035..2421)
                     /locus_tag="VXF95_001786"
     CDS             complement(2035..2421)
                     /locus_tag="VXF95_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HEV1082294.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            complement(2414..3757)
                     /locus_tag="VXF95_001787"
     CDS             complement(2414..3757)
                     /locus_tag="VXF95_001787"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HEV1082295.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFATADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            complement(3844..4728)
                     /locus_tag="VXF95_001788"
     CDS             complement(3844..4728)
                     /locus_tag="VXF95_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082296.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGKLVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFERETASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEILLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKAGQVIGTCTVDLSSDT
                     NYFYGLAISEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            complement(4740..5357)
                     /gene="cysE"
                     /locus_tag="VXF95_001789"
     CDS             complement(4740..5357)
                     /gene="cysE"
                     /locus_tag="VXF95_001789"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HEV1082297.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHSFKLLARMHSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHAVEEKREYYVNKLEQAKDASHRSSGL"
     gene            complement(5373..7586)
                     /gene="pnp"
                     /locus_tag="VXF95_001790"
     CDS             complement(5373..7586)
                     /gene="pnp"
                     /locus_tag="VXF95_001790"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HEV1082298.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELIAFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYADHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHHKDHKPKKEFTETPKDSE"
     gene            complement(8271..9137)
                     /gene="metF"
                     /locus_tag="VXF95_001791"
     CDS             complement(8271..9137)
                     /gene="metF"
                     /locus_tag="VXF95_001791"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HEV1082299.1"
                     /translation="MSCQTPSLSFEVFPPNPAVGNDNIILALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIADLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIELIKEQAPHFDIIGACYPEGHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNEHFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            complement(9201..11450)
                     /gene="metE"
                     /locus_tag="VXF95_001792"
     CDS             complement(9201..11450)
                     /gene="metE"
                     /locus_tag="VXF95_001792"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HEV1082300.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFNEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVVAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYAGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYLFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
BASE COUNT         3233 a         2599 c         2265 g         3435 t
ORIGIN      
        1 attgaaacta gaataatata cctctacttc taaaatattg ttagaaatcg atttgacttc
       61 cctgatcgat tcgtcctatt cttatttcat tttactataa ttgatagtgg tcgccccagc
      121 cagatacctt atctgctatc catttaggaa cccctaactt aagcaatccc cataatcgtc
      181 tcgatttctt cttccattgc ttccagataa tcactcgtag gcgagtacgc aagcgctcat
      241 ctatgctagt gactatactt ttcatattta taattcattc ctttcgtttc actcaaggca
      301 caacacagaa tgaaaaagtg ttgtgatctt tattttgttt tataataata gtgagaaagc
      361 ctatcactac tacaaatcac ggggaggtga ataagtgagt ggtacagcca ctacctcgca
      421 tattttgtca catcatttaa cggtacataa taagttgtac catctgaata agttgctaca
      481 atatcatttg catgctctcc ttcaccttta gcaaaggttg gagctcctgc tggatgattt
      541 ttatttgcct ctttcaattt ttcaataatg gcattttttt ctgtatcttt tatattatca
      601 ggatttttca ctaagatttt gtctggatat gtcggtttag cagaaacaat ttttactgtt
      661 acttcttttt tattcgaagc acttgtccag tttccagcat tatctttagc atttaatttt
      721 acagtaattc ctgaactagg aacttcagta gcaggttgat tatcaacatt attcaacttt
      781 aatttcaaaa gagctgttgc atcagacgtt ttatcaatcg ttatatataa tgatgaattg
      841 ttattataac cagttccttc atatttagct gtttgtgagc tacttgaaac agaactgaaa
      901 ttatacccac tacctccctg attatcttca atgcttacgt ctaaatgaac ttccccacta
      961 ttatttggct tagcaacaac tgttatagta aaataacata aaatttgcat aaatagatta
     1021 gggaaatcaa agcagcttct aggaatgttt tagcagtcac agtgtacttt cccagcatca
     1081 agccactata actctgcaca taaaaatgga gaagatggca atcctcttct ccaaatatta
     1141 acttctttac aaaccaacta tagttgacaa agaacctaaa atcaattgat aacacaaggt
     1201 caggtcggtc aactctttca actgaagccc tgtcaactct tcccatttat caatcttgta
     1261 ttggagagaa ttgcggtgca gatagagttg ctgggctgtt ttagtgagaa cagcactatt
     1321 ttcccaaaga gagagaatga tttcctgaat ctgatcttga tccaaaatca tctggtgtag
     1381 acattcttta attggcttca agtccacgag tctttctccc atactccaaa gatagagctg
     1441 agaaaaagta tgaacacctt ggtgaccctg acgccaccat gtcttgaaca aatcccgctc
     1501 agctttgatt aagtctgata gggcttgatg tcctgtctga gaccaaacct gacccaacat
     1561 gatagaaaga cgaagtccaa aatcatactc aaccgcttca atcgtatcac ttaaaatatc
     1621 tcttacagaa gtgtatttgt cttgttgaag cacgaaaaca taatcctgag ctccgacctg
     1681 tagcactgtc tgacaattcg gaaaaagagt ccgcatcata tctagccaag aagtcagatt
     1741 ttcctgctga aaataagaaa gatggcaata aaccaactga atctttttaa aaacttgcgg
     1801 tgcctgtccc ttgccttcaa ccagatagga ataccaaggg tttagcgaac gagcctgctc
     1861 ctgctgggtc aaaagggcaa ccaactgctt ttcacgctcg ctgagcccag cttcctccag
     1921 caaaatccac tgctgagaag ctaaagggag cgtgagatag ccctctttct ctactggttg
     1981 gtctgaaatc cgagcctcag gaaaccagtc ttgtagttct ttttccctca tgttctagcc
     2041 ctccactttt tggatgcacc atgaaaccaa actctcaaga cgttccagat tctcagtcat
     2101 atggagatag cccataaccg cttcaaatcc cgtggacata cgataagtca cgacatctgc
     2161 atttttagcc tttgtgtggc tattggtatt gcggccacgt ttgtagattt cttcttcttt
     2221 ttccgttagg acctgctcct ccaacatgag agcaatcagg cgagcctgag ccttggctga
     2281 cacatacttg gttgcttctt gatggagttt attgggtttg gtcatacctt tgaggatgag
     2341 gtgacggcga atatacatag aatacaccgc atccccctca aaggctagcg caatcccgtt
     2401 aatgagattg acatcaatca cgtgtccacc tcactccatc cttggtatca aggagcttaa
     2461 ttccttgagt aaccaattgg tcacggattt ggtctgctgt cgcaaagtca cgattggcac
     2521 gcgcctcttg gcgtttttga atcaagtctt caatctctgc atccaaaact tcctcaacaa
     2581 agacaattcc aaaaatttct aacatatctg caagagcttg cttgacactt gcatcatagt
     2641 tccctgagtt gatccatttg gccatttcaa agacaactgt gataccgttg gcagcattaa
     2701 aatcttcatc catagctgct acaaacttat ctttaaagtt ttgtaactct tgggcatcca
     2761 cgtttcctgt aaatggttgt tcgtaagtat tcttcagata cttgagattg gtctcggcat
     2821 cgcgaactgc cttttccgtg aagttgatag gcttacggta gtgctgggtc gcaaagaaga
     2881 aacgaagtac ttgcccatca agagttttaa gggcatcgtg taccgtaatg aagttaccca
     2941 aggacttaga cattttgaca ttgtcgatat tgacaaagcc attgtgcatc cagtagttag
     3001 caaaagcctt gcctgtttta gcttcagatt gggcaatttc attggtgtgg tgtggaaact
     3061 ctaggtcagc tccaccaccg tggatatcaa tggtatcacc taaaatctct gtcgacatga
     3121 ctgaacactc aatatgccaa cccggacgtc caggtcccca aggactatcc caagaaatct
     3181 cacctggttt ggaagatttc catagagcaa agtctacagg attttcctta cgagccgttt
     3241 cttcatcggt acgacctgaa gcacctagct ccaaatcttc caaggtttta ttagccaatt
     3301 tagcatagtt gtgggatttt tctacacgga aatagacatc cccttgactc tcataggcaa
     3361 agcctttctc gatcaagtct tccacaaaac ggatgatgtc tgccataaac tccactacac
     3421 gcggatggcg agtcgcaggt ttcacgccca aggccgtcac atcctcacga aaggcagcga
     3481 tgtacttatc cgcaacctcc tgaggcgtga tgccttcttc cctggcacgg ttgataatct
     3541 tatcatccac atctgtaaaa ttggaaatat aggcaacctt atacccacgg tactcaaaat
     3601 agcgacgaat cgtatcaaaa gctaccgtcg aacgggcgtt tcccacgtgg atatagttgt
     3661 acaccgttgg cccacaaaca tacatcttga tcttgccgtc ctcaatcggg acaaattctc
     3721 gcaaatcacg agacatggtg tcatagattt taatcataaa tcataatcag gaaagctaaa
     3781 atccaagaac tgttagtttc atcactaaac taagagctca agtaaatttc agtccgaatg
     3841 tctctacact tcggaatccc ttgctccttt ctcattcaga taaaccacct gtgtctgttt
     3901 gacaaagcca attttttcat acaaacgttt ggcacctaca ttgctatctt ccactgcaat
     3961 ctgaaattcc ttatcatttt gctcaattag ttggttgaca agggattttg ctaagtagct
     4021 tccatagcct ttcccacgtt caggttctga tattgctaaa ccgtagaagt aattcgtatc
     4081 gctcgataaa tcaaccgtgc aagtcccaat aacctgacca gcttttaata aaatatatag
     4141 tcggctttct ggatctttca gagcttcagc gacatatcta tccacaactt ctctcgattc
     4201 atgttcctct gaaaatgcct gaaattttaa ttgactaatt tgatcctgat acgaactatc
     4261 tgctaacaaa atttcaagat gggaaacatt tgctaacgga taaggtcttc tatccttacc
     4321 taaccaagtt tctgtctctt catcctcgat tagtccccag ttactggcaa agtcaggatg
     4381 attctctaaa aaaatacgtt ctgtctgaaa agtgactgac cgaataggga aagaagctgt
     4441 ttctctctca aaactagtaa acaatgcacg cgcaatcccc tgacggcgat gacctggatg
     4501 aaccagtatc gtcacttcta catcttggtc atctgcatag acagttaata aaccaacaag
     4561 tttgcctttt tcataataaa ggaaaaaggc gggcatgttt gggtcaaaat taagcatgtt
     4621 agagagatag ggatcgcgat aggtaccgtc atagttttgg caacagttaa ttactttttt
     4681 cgcctcagat agctcctctt ggcttaactt gtttcttgct tgaatcatat aggtatcctc
     4741 tacaaaccag acgatctgtg actggcatct ttagcctgct cgagtttatt gacataatac
     4801 tctcgttttt cttcgactgc gtgaataaca ggctcatctt tcttaccatg aagacggaca
     4861 atcttggccg gaataccgac aaccgtcaca tcactaggta catctgctac gacaactgct
     4921 gcagcaccga ccttggcatt ttcaccaatt tccacaggtc cgataacttg ggcatgggct
     4981 gatatgaggg ctccctttcg tacagtcgga tggcgtttgc cacagtcttt ccctgttccc
     5041 ccaagagtca ctccgtgata gagaagaacg cctttttcaa caatcgctgt ctctccaatc
     5101 accagaccag aaccatggtc aataaagaca cctgaatcaa tctgggctcc tggatgaatc
     5161 tcaatctgag tccaaaagcg ccaaaactga ctgtgcatac gagctaagag tttgaagctg
     5221 tgcttccaga gaaaatgcga gagacggtgg gccgccaagg ccttgacacc tggataagtc
     5281 agcaaaacct ccaaagtggt gcgggccgct ggatcatttt cttttacgat atcaatggtt
     5341 tcgcgccacc accccataca tttctccttt tcttattctg aatcttttgg tgtttctgta
     5401 aattctttct taggtttgtg atccttgtga tgacgtgggc ggtgagggcg ctcagacttt
     5461 tcaccttttt catcatgctc aggttttggc ggacgaggta gaagagcctt catagaagca
     5521 tcgatacggc ctttttcatc aatcttgata accttaacat caacttcatc cccgatttct
     5581 accaaatcct ctacacgatt ggtacgagtc caagccatct cagagatatg aacaagggca
     5641 tctgtcttat caaagaggtt aacaaaggca ccaaatttct cgatacgaac gactttagca
     5701 cggtaaactt catccacttt ggcttcacga accaaaccag caataatttc tttggcacgg
     5761 ttaatagcat cttggtcact agagtagata gacacatttc cttcttcgtc tatatcaatc
     5821 ttaacacctg tttcagcaat aatcttgtcg atggtttctc cacccttacc gatgacaatc
     5881 ttaatcttgt ccacatcaat cttgatcgta tcaattttcg gagcagttgg agccaattct
     5941 ggacgaactt ctggaatggt tgcttcaatg acatcaagga tttcaaaacg cgctttcttg
     6001 gcttgagcaa gagcctccgt caagatttct gcagtaatcc cttgaatctt gatatccatt
     6061 tgaagggctg taatcccatc acgagtacct gcaaccttga agtccatatc tccaaagtga
     6121 tcttccaaac cttggatatc tgtcaatact gtgtagttat ttccatctga gataagtccc
     6181 atagcaatac cagctactgg cgccttgatt ggcacaccac cagccataag ggcaagagtt
     6241 cccgcacaga tagaagcttg agatgaagaa ccgtttgatt ccaaaacttc tgctactaga
     6301 cggatagcgt atgggaattc ttccaagctt ggcaagactt gagcaagagc acgctcacca
     6361 agagcaccgt gaccgatttc acgacgacct ggcgcaccgt aacgacctgt ttcccctaca
     6421 gaatattgag ggaagttata gtggtgcata aagcgtttct tgtactctgg atccaaacca
     6481 tcaatgattt gagtttctcc catcggagcc aaggtcaaga ctgaaagagc ttgagtttgc
     6541 ccacgagtaa agagacctga accatgtaca cgaggaagga agtcaacaac cgcatccaaa
     6601 ggacggattt catcgacctt acgaccatca ggacgcacct tgtcttctgt aattaaacgt
     6661 cgcacttctg cgtgttccat ttgttccaag atttcagcca catcacgcat aatacggtca
     6721 aattcttcgt ggtccgcata tttttcttcg taaacggcag tcacttggtc tttcactgct
     6781 tgagttgcag cttcacgggc caatttctct tctacttgaa ctgccttttg gaggtcactg
     6841 ttgtaggctg caatgatttc agcttgcaat tcagcatcca cgtgaagcaa ttccacttct
     6901 gctttttctt taccgacagc agcaacgatt tcttcttgga aggcaatcaa ttctttgaca
     6961 gcttcgtgcc ctttaagaag cgcttccaac atgatttctt ctgacaattc tttggcacca
     7021 gactctacca tgttgatagc gtgcttggtt ccagctactg tcaattcaag aagagattgc
     7081 tctgcttgtt cttgacttgg gttgatgatg atttggccat ctacatatcc cacttgtacc
     7141 ccagcaattg gtccgtcaaa tggaatatct gaaatagaca gtgccaaaga tgaaccaaac
     7201 atagcagcca ttggtgcaga tgcattttca tcataagaaa gcactgtatt gatgacttgg
     7261 acttcattac ggaaaccttc cgcaaacata ggacgaatcg gacggtcaat caaacgcgct
     7321 gtcaaggtcg catctgttga aggacgtcct tcacgtttca taaagccacc aggaaacttc
     7381 ccagccgcat acattttttc ttcgtagttg acttggagtg ggaagaaatc cccagttgcc
     7441 attttcttag acataacggc agcagtcaag acagttgact caccgtaacg tacgacaaca
     7501 gatccatttg cttgcttagc aacctgacca gtctctacaa ttaactcacg acccgcaaaa
     7561 gtcgtttgaa acacttgttt tgccatttta atcccctttg gattgatgaa attatacgcc
     7621 ttgcctacaa agatcaagat accaaggacg tcaaaagcaa agtaaaaata ggaaactgac
     7681 gaagtcttcg atgaagacaa gacagtttat cttttttaca cagcttttcg gccgtgttca
     7741 attacacaag atattttgga cggttcggct tgccgaacat ttctgtagaa aaataggaag
     7801 gtgacttcgc actcgacgag tgctaggaag cttatctttt ttcctaagaa atgagaccaa
     7861 aattcaagtc atcaagatac caagccgtca agcaactcaa aggaagatag gaaatcgaac
     7921 gacggagcga ctgctcctag ggagatttat ctttttccac agagttgtag gcaagttcag
     7981 ttttcaagat acatcattag aaaggtttaa tactaaagta tctaaagctt tcacgctaat
     8041 cgctatcggg cgattagcta aatgctttac taactctctc gtcaaataac atcgatttga
     8101 ctcactcgtg tcgttaaatc ttacagttta aatgcattgt attatttaat accttcatct
     8161 ttgtatcaag tacgtacaga atttatttta tcatattttt cttaaaaagt gaggtcttta
     8221 ccattaaaaa ggaaccattc ccctcacctg agaagaatgg tttgctttta ttatcctaga
     8281 gactggtgat taaacaaggc atgggttgct tgatggatgt attttgctgt atcagcatta
     8341 ttcatcgtat agagatgcac accggcaaca tcctgagtta ccaagtctac gatttggtcc
     8401 actgcatagg caagtcctgc tgctctgagc gactcagggt catgctcata cttgtctaag
     8461 atggctttaa atttgcgtgg aagatggata ttctcacaag tcttcaagag tcggagagcc
     8521 tgatttcgat tcagaattgg cataattcct gcatgaatgg gaacatcaat cccagccaag
     8581 atgcacttgt cctgaaaatc atagaagtgc tcattgtcaa agaagagctg agttacgagg
     8641 ctcgaacagc ctgcatccac tttcttctta agattttgaa tatctgaaat ctgatttggc
     8701 gaatctggat gcccttctgg atagcaagct ccaataatat caaagtgagg ggcttgttcc
     8761 ttgataagct caatcaagtc ggttgcatag cggaaatcct tttgtggttc cacgtctgga
     8821 ataatatccc cacgaagagc caagattttc tgcaccccaa ctttgtccaa gtcagcaata
     8881 gtttcagcaa ccttgtcctt agttagataa atagctggca agtgggcaat ggtcggaatc
     8941 gccaagtcat tttggataaa gtcagccaaa cgaaccgtcg tttccttgat attaaattta
     9001 ttattgctgg cagttacact gataaaatgg ggagccaact cctgcatatc ctgcaaggct
     9061 aaaataatgt tatcattacc cacggctggg tttggaggga acacttcaaa tgagagtgac
     9121 ggtgtttggc atgacatatg taataacctt ttctagttga tttctttttg aacaaccact
     9181 gtatggagag aaatccaatc ttacaatttc tcacgcgcag ctttagctgc ttcaacaagg
     9241 cggatcaagc tttcttttgt ttctgggata ccacgtgttt tcaaaccaca gtcagggttg
     9301 atccaaactt tcttgcttgg cactttagca aggatggctt cgattgtgtt gtcgatttcg
     9361 ccttcatttg gtacacgagg tgagtggata tcgtaaaccc caggtcccac ttctgtttgg
     9421 aagtttttcg ctttgagttc gtccaagatt tcaaggtttg aacggctggc ttcaaaggaa
     9481 ataacgtctg catccatgtt atcgatagct gggatgatat ctgtaaattc tgagtaacac
     9541 atgtgagtgt ggatttgtgt gtctgacgct actgttgagt gtaccaagcg gaaggcagga
     9601 attgcccagt caaggtaatc ttcgtaccag tcactacgac ggagtggcaa tttttcacga
     9661 agagcagcct catcaatttg gatgattttc acaccagcag cttcaaggtc aagcacttca
     9721 tccttgatag caagggcgat ttgaagagta gaatccttga tagagatgtc ttcacgtggg
     9781 aatgaccagt tgaggatggt aacaggtcca gtcaacatac ctttaacagg tttgtttgta
     9841 cgactttgtg catagctaga ccatttaaca gtgatagggt taagacgagt gacatcaccc
     9901 cagatgattg gtggttttac cccacgcata ccgtatgatt gtacccatcc atttttagag
     9961 aagaggtatc ctgacaagtt ttgaccgaag tactcaacca tgtcattacg ctcaaattca
    10021 ccgtgaacaa ggacatcaaa gtcaatatct tcttgccact tgatccattc gtcaatcgtt
    10081 tcagcaagga aagcgtcgta ctctttttga gacaattcac ctttacggta agccaaacgt
    10141 ttggcacgaa cttcttttgt ttgagggaat gaaccaatcg ttgttgttgg aagagctgga
    10201 agtttaaaag cttcttcttg gatagcttca cgttctgcaa aggctggcaa acgagtgtag
    10261 tctgcgtctg tcaagccagc gatacgcgca cgaagttcag cattttcacc aacacgctca
    10321 gtcgcaaaga gttctttgtt ggctgcaaga gcttctgaac cttgaccatt gcggatagca
    10381 tccaagtcac ggatttcatc caatttttca actgcaaagg caaagtggtt caagagtgct
    10441 ggttcaaatt cttcattagc agttgtaaat ggcacatgaa gaagtgagca agagcttgtc
    10501 aaaacgatgt tttcagctgg gatttgctca agaacagcca agctcttttc gtagttgtta
    10561 cgccagatgt ttttaccatt gacaatacct gcatagagag tcttgtcagc tgggaagcca
    10621 cctttaacga gttcaagagt tttcttacct tcaacaaagt caagaccgat agcatctact
    10681 ggtaagttta caaggtcagc gtatacgtca cgaacatcac cgaaataagt ttgaagcaag
    10741 acttcaagac cttttttgtc agccaagagt ttgttgtaaa ggttcaagaa gagagctttt
    10801 tcttcagctg tcaagtcttt tacaagagcc gcttcatcca attggatgcg agtcgcacca
    10861 agttcagcca atttagcaaa aacttcttgg taagcaacta ctaagctatc tacgaagtcg
    10921 tctgctttca cgccttcttc aaagtctgac aattgaagga aagtgaaggg acctacaaga
    10981 acaggacgag tgttcaatcc aagttctttt gcttcttgga actcattgaa aatcttgtga
    11041 ccagccaatt ttacttgagt gtctttttca aatttaggaa cgatgtagtg gtagttagtg
    11101 ttgaaccatt tcttcattgg aagggcgcga acgtcccctt tttctccctg gtaaccacgt
    11161 cccaaagcga agtagcgctc aaggtcagac aagtccaagt tttgaacgga tgcaggcacc
    11221 acgttgaaaa ggaaagccgc atctaggaag ttatcatagt gagaaaagtc atttgatgga
    11281 atttcagtga tgcctttttc tttgacaatg ttccagtgtt tagcacgcaa gtcttttgct
    11341 gctgctaaaa gttcttcttc tgagatttct tttctaaagt atttttcagt tgtaaatttt
    11401 aattcacgga attcgcccaa acgagggaaa ccgatgattg tagttgacat gatgtgtcct
    11461 ccaaaatttg ttgttgaaac tatcttaaca gaaaagaaag cgtctgtata attgtaaaaa
    11521 attagggttt ga
//
LOCUS       DAVLMQ010000056        11211 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000056 DAVLMQ010000000
VERSION     DAVLMQ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11211
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.056"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(101..1672)
                     /gene="ffh"
                     /locus_tag="VXF95_001793"
     CDS             complement(101..1672)
                     /gene="ffh"
                     /locus_tag="VXF95_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HEV1082301.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPD
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(1684..2016)
                     /locus_tag="VXF95_001794"
     CDS             complement(1684..2016)
                     /locus_tag="VXF95_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HEV1082302.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            complement(2107..2484)
                     /locus_tag="VXF95_001795"
     CDS             complement(2107..2484)
                     /locus_tag="VXF95_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HEV1082303.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKDSDSLAYIPTPMGMQEFTIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWV"
     gene            2556..3860
                     /locus_tag="VXF95_001796"
     CDS             2556..3860
                     /locus_tag="VXF95_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1082304.1"
                     /translation="MNEKVFRDPVHNYIHVNNQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMTAALLHDLGHGAYS
                     HTFENLFDTDHEAITQEIIQNPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPEDKDFFARTSPHLLPFFEKNVTLTD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSISFSQEDQDQLASMRKLAE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLHLIENDHFTPNKN"
     gene            3873..4679
                     /gene="yidA"
                     /locus_tag="VXF95_001797"
     CDS             3873..4679
                     /gene="yidA"
                     /locus_tag="VXF95_001797"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HEV1082305.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGKYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKTNDESGVAHAIRTWVL"
     gene            4722..5720
                     /locus_tag="VXF95_001798"
     CDS             4722..5720
                     /locus_tag="VXF95_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HEV1082306.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNELECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLTVVELKTILSKHN
                     LATSGKKAELITRIINNVNIDNLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDITMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(5887..5958)
                     /locus_tag="VXF95_001799"
     tRNA            complement(5887..5958)
                     /locus_tag="VXF95_001799"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5923..5925),aa:Arg,seq:cct)
     gene            complement(6000..6347)
                     /gene="rplS"
                     /locus_tag="VXF95_001800"
     CDS             complement(6000..6347)
                     /gene="rplS"
                     /locus_tag="VXF95_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HEV1082307.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            complement(6466..6795)
                     /gene="crcB"
                     /locus_tag="VXF95_001801"
     CDS             complement(6466..6795)
                     /gene="crcB"
                     /locus_tag="VXF95_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1082308.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQASKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            complement(6789..7163)
                     /gene="crcB"
                     /locus_tag="VXF95_001802"
     CDS             complement(6789..7163)
                     /gene="crcB"
                     /locus_tag="VXF95_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HEV1082309.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            complement(7160..7426)
                     /locus_tag="VXF95_001803"
     CDS             complement(7160..7426)
                     /locus_tag="VXF95_001803"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HEV1082310.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREAVIFEKVRSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            complement(7542..7985)
                     /locus_tag="VXF95_001804"
     CDS             complement(7542..7985)
                     /locus_tag="VXF95_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HEV1082311.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            8089..9024
                     /locus_tag="VXF95_001805"
     CDS             8089..9024
                     /locus_tag="VXF95_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HEV1082312.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVGAPGRIDRVSLWGIFVEQADGHYRVRLRSKVHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            9078..9362
                     /locus_tag="VXF95_001806"
     CDS             9078..9362
                     /locus_tag="VXF95_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HEV1082313.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(9419..9907)
                     /locus_tag="VXF95_001807"
     CDS             complement(9419..9907)
                     /locus_tag="VXF95_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HEV1082314.1"
                     /translation="MSSYFVKITDASKAVKNGDQAEVQKLVTKMASDFERVENKDSEV
                     GKIVKEKLALSGDITEAKLTEISSALLAFEKEQNPVDLDAEKEKLVNRLSPRFETLEQ
                     AIASKDLEKVREAFKKMNSTWTINESVVRDNSTAHYGRVETAISFLPSSMETEPTDES
                     GT"
     gene            complement(10021..10692)
                     /locus_tag="VXF95_001808"
                     /pseudo
     CDS             complement(10021..10692)
                     /locus_tag="VXF95_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259617.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            complement(10695..11154)
                     /locus_tag="VXF95_001809"
                     /pseudo
     CDS             complement(10695..11154)
                     /locus_tag="VXF95_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
BASE COUNT         3464 a         2480 c         1979 g         3288 t
ORIGIN      
        1 gtataatatc agatattcta aaaccttgat actgtacgtt ttatcataga aatttttact
       61 ttattttctc atcaaatgag atttgcatca atctcttgtc ttacttgcgt ttcttcttcg
      121 ctttcttcat tttgttagcc atacgtttca tggactgttt catggcaaat tcaccaattt
      181 tacctttcaa accgccacca aacatctggc tcatatctgg cattcctgct cctccgagag
      241 ctgataagtc aggcataccg ccttgtccca tcattccttc aagggcagac atatccattc
      301 ctcccatatt tggcatattt ttaggaaggt tatttggatt aatccccatt tgcttcatca
      361 ttttattcat atccccagac ataacaccct gcatgagctg tttagcctgg ttaaagtcct
      421 tgatgaattt attgacttcg acgaatgtat ttccagaacc agcagcaata cgacggcgac
      481 ggcttggatt taacaaatct gggttttcac gttcttcagg tgtcatcgaa gacacaatgg
      541 cacgtttacg agcaatctgg cgttcatcca ccttcatgtt ttgaagtgct ggattgttgg
      601 ccatacctgg aatcatcttg agcaagtctt ccatcggccc catattttgc acctgatcta
      661 attgatcgat gaaatcatta aaatcaaagg tgttttcgcg catcttctca gccatttcaa
      721 gggctttttg ttcatcgtat tcctgagaag ctttctcaat caaagtgagc atatccccca
      781 tgccaaggat acggctagac atgcggtctg ggtggaaggt ttcaatgtcc gtaatctttt
      841 cacctgtacc agtgaacttg attggttttc cagtaatgtg acgaacagac agagcagcac
      901 caccacgagt atcgccatca atcttggtaa ggatgacccc agtcacttcc aactgagcat
      961 taaactcacg cgcaacattg gctgcttcct gaccaatcat agcatcaacg acaagcaaga
     1021 tttcatttgg ttgagccaat gctttcacat cacgaagctc attcatgagg agctcatcaa
     1081 tctgcaaacg acccgcagta tcaatcaaga catagtcgtt atgattagtt tgggcttgct
     1141 ccaaaccttg acgtacaatc tcaacagctg gtacttctgt tccaagtgca aagacaggca
     1201 catcaatctg ttgtcccaag gtcttaagct ggtcaatggc agctggacga taaatatccg
     1261 ccgcaatcat caaaggacga gcattttctt ctttcttgag tttgttggcc aatttaccag
     1321 caaaggttgt tttaccagcc ccttgtaaac caaccatcat gatgatggtt ggaatcttag
     1381 gtgacttgat aatttctgcc gtatcagaac ctaaaacggc tgtcagttcc tcatcaacga
     1441 ttttaataat ctgttgcgca ggattaagtg tatcaatgac ctcatgcccg actgcacgct
     1501 cacgaacttt cttgataaag tcctttacaa caggcaaggc aacgtcggcc tcgagcaagg
     1561 ccaagcgaat ttctttggtt gcctcttgga catcagattc agagattttt ccttttttac
     1621 gtagattttt aaagacgttc tgcaaacgtt ctgttaaact ttcaaatgcc atttttcttc
     1681 ctcttattct ctattatcaa tgcttgttaa aatttctatc tgctcctgca gaaagttatc
     1741 cttgggatag cgctccaaaa tctgatcaaa aatctgactg cggacaatat agtccgagta
     1801 catgtgcaat ttcatctcat aatcttccag aatcttttct gttcgcttga tattgtcata
     1861 gacagcctga cgactgacac cgaactcctc ggcaatttca gcaaggctgt aatcatcagc
     1921 gtagtagagc tcgatataat tcatttgctt atctgtcaaa agcgccgcat aaaattcaaa
     1981 gagcgcattc atacgattgg ttttttcgat ttccataact tttattatac caaaaattag
     2041 cctaatctac cacactagga agccgatcca agaagataga tagctaaatt tgaaaaagac
     2101 atgagcctag acccaagtaa tttccaattg atagctggca aagggatgtc cctcttgatt
     2161 ttgtagttga taatctagtt caatcttttg cctatcaact tgataatggc tcgtttggat
     2221 ggtaaactcc tgcataccca taggtgtggg aatataggct aaactatcac tatcctttag
     2281 aaagcgcata atggtcttgg gattggaaaa tcgactcatc acaagttctt gaccatgaaa
     2341 tttaatcact actttttcct tttcctcatt atagaaaagc aggtagctat aatctccttt
     2401 ttcatgcact tccacatcat aaagctggtc aatcacttcc aactgctcat caaactgaat
     2461 tgtatttcgc atccgaatct tcacatcagg ccctctttct tgtctcttgt cctactattt
     2521 taccaaaaag agcaggattt tgctataatg gtcatatgaa cgaaaaagta ttccgtgacc
     2581 ctgttcacaa ctacatccat gtcaataatc aaatcatcta tgacttgatt aatacaaaag
     2641 aatttcagcg tttgcgccgg atcaaacaac tgggaacttc cagttatacc ttccacggtg
     2701 gagaacacag tcgcttctct cactgtctag gagtctatga aattgcacga cgcatcacag
     2761 agattttcga agaaaaatat cctgaggaat ggaatcctgc cgagtctctc ttgaccatga
     2821 ccgctgctct cctacacgac cttgggcatg gtgcctactc ccatactttt gaaaatctct
     2881 ttgatacaga ccatgaagcc attactcagg agattattca aaatcctgag acagagattc
     2941 accaagtcct gctacaagtg gcacctgatt tcccagaaaa ggtggccagt gtcattgacc
     3001 atacctatcc taataagcag gtcgtgcagc tcatttctag tcagattgac gcagatcgca
     3061 tggactatct cttgcgcgac tcctatttta caggagcatc ctatggggaa tttgacctga
     3121 ctcgaatcct ccgagtcatt cgtcctatcg aaaatggtat cgcctttcag cgcaatggca
     3181 tgcacgccat cgaagactac gtcctcagtc gctaccagat gtacatgcag gtttatttcc
     3241 accccgcaac acgcgccatg gaagttctcc tacagaatct tctcaaacgc gccaaggaac
     3301 tctatcctga ggacaaggat ttctttgccc gaacttctcc acacctcctg cctttcttcg
     3361 aaaaaaatgt gaccttgact gactatctgg ctctggatga tggcgtgatg aatacctact
     3421 tccagctttg gatgaccagt cctgacaaga ttcttgcaga tttatcgcaa cgctttgtca
     3481 accgcaaggt ctttaaatcc attagctttt cgcaagagga tcaagaccaa ctcgccagca
     3541 tgagaaaatt agctgaggat atcggctttg atcccgacta ctacactgcc attcataaga
     3601 actttgacct cccttatgat atctatcgtc ccgaatctga aaacccacgg acacagattg
     3661 agattttaca aaaaaatgga gaactggcag aactctctag cctgtcccct atcgtccaat
     3721 cccttgctgg aagtcgccac ggagataatc gcttttattt cccgaaagaa atgttagacc
     3781 aaaacagcat cttcgcaagc atcacccagc aatttttaca cttgattgag aacgatcatt
     3841 ttaccccaaa taaaaactaa aagaggaaat ttatgagtat taaactaatc gccgtcgata
     3901 ttgacggaac cctagtcaac agccaaaagg aaatcactcc tgaagtcttt tctgccatcc
     3961 aagatgccaa agaagctggt gtcaaagtcg tgattgcaac tggccgcccc atcgcaggtg
     4021 ttgccaaact tctggacgac ttgcagttga gagaccaagg tgactatgtg gtgaccttca
     4081 atggtgccct tgtccaagaa actgctactg gccatgagat tatcagcgaa tccttgacct
     4141 atgaggatta tctggatatg gaattcctca gtcgcaagct cggtgtccac atgcatgcca
     4201 ttaccaagga cggtatctat actgcaaatc gcaatatcgg aaaatacact gtacacgaat
     4261 caaccctcgt cagcatgcct atcttctacc gtacccctga agaaatggct ggcaaggaaa
     4321 ttgtcaagtg tatgttcatc gatgaaccag aaatcctcga tgctgcgatt gaaaaaatac
     4381 cagccgaatt ttacgagcac tactctatca acaaatctgc tcctttctac ctcgaactcc
     4441 ttaaaaagaa tgtagacaag ggttcagcta ttactcactt agctgaaaaa ctaggattga
     4501 ccaaagatga aaccatggca atcggtgacg aagaaaatga ccgtgccatg ctggaagtcg
     4561 ttggaaaccc cgttgtcatg gaaaatggaa atccagaaat caaaaaaatc gccaaataca
     4621 tcactaaaac aaatgacgaa tccggcgttg cccacgccat ccgaacatgg gtactgtaaa
     4681 agtatcattt ttcaataaga attgattagc aataaaatcc aatgaatttt tttagcaaac
     4741 tatttaattt aaaacaaaat aatcataata gagacacaaa ttctgattgt aacaattttt
     4801 acctaaacga attagaatgt ggccttactc ctgggcaact catactcata gattggactc
     4861 aaaaaacagg gagaaattat aatttcccaa gatattttaa atactctctt caaattgacc
     4921 ctgaatctac acacaatcaa ttatacaaat taggatactt cactaaaaat aagactttat
     4981 catatcttac agtagtagaa ttaaaaacta tattatctaa acataattta gctacttctg
     5041 gaaaaaaagc agaattaatt acaagaataa ttaataatgt taacattgac aatttagata
     5101 ttccgttcga atttaaacta acaaaagaag cacaaaatct tattatcgaa catagtgact
     5161 atatcaaagc atactatgat aaagacataa ctatggaaga ttattgtaaa gaaaaaaaca
     5221 atatctcttt taaagcaact tttggtgata taaaatggag tctcttaaat aaacaagctc
     5281 ataggaatac tgtatcagga gattttggat gcttatctaa cacacgaaag gctcagggaa
     5341 gacatttgga acaagaaggt aatattaaac atgctttaat atattacata gaatctttga
     5401 taattactat ttcaggatta gaaaacaatt tttcagccac tgattatcca gtatattatc
     5461 ccgattcgat acctgactac tcactaaaac atattcaaac attaatggaa tcattatctg
     5521 atgacgatta tgattttgct tttgatgaag cattatttcg cttctcaatt ttgaatgcaa
     5581 atcatttttt atctaaggaa gatattgact atttaagagt taatttacct cgttccactg
     5641 ctgaagaaat aaacaattac ttaaagaaat atgaatgtta tagtccttta aataatttag
     5701 aacttgacga ttttgaataa attgactata caaacattta tatactcgat atagtctcaa
     5761 ttttatctga tgattgccca aatttttcaa taataaaacg cataatatta tggagacaat
     5821 cccctatatt atgcgttctt ttaatatcaa agactttttg acaaacttct ttgatatcta
     5881 attacatgcc ccctgcagga atcgaacctg caactactcc ttaggaggga gttgttatat
     5941 ccattgaact aagggagcta gataaaaact ctgctgaaaa gcagagtttt ttagtcgaat
     6001 taacgacgga tttctttgat acgagctgcc ttaccttgaa gagcacgcaa gtagtacaat
     6061 ttcgcacgac gtactttacc gtaacgtaca acttcgattt tttcaacacg tggagtgtgg
     6121 attgggaaga tacgctcaac acctacaccg ttagagattt tacgaactgt gtagttttca
     6181 gagatgccag cacctttacg tgcaataaca acaccttcaa aaatctggat acgttcacgg
     6241 ttaccttcga caactttcgc atgtacacga acagtgtcac caggacggaa tgatgggata
     6301 tctgtacgaa gttgaccttc agtcaagctt tggattaatg gattcatttt attctcctat
     6361 ctttgtcaat cttgaggaat cttcctcagc ggataaactg tatttttgtg cgtccattac
     6421 acacaagata tagtttacca aatttctaaa aaaaagtaaa gaaatttata gcaaaattcc
     6481 taaaaaaatc gcaaccaaac cacctatgta agtcaaagtc aggtaagaat aaaagacctt
     6541 cttatcactt agcagtcttt gaagttcgtc attcaaggtc gaaaaagttg ttaaaccgcc
     6601 acaaaatcct gttgctagaa tagcatatac ttccttagac tctacatgat tgtagaatac
     6661 tccaattaaa aaacaaccta aaagattagc tatgagcgtt ccgagtggca atttagaagc
     6721 ttgattatag cgagaaaaga aataccgtac gagtgctccc aagccacagg cgattgcaag
     6781 atagacgatt accatttctt cctccccaaa tagtaagcta aaagcaggcc tccaccgata
     6841 ctcaaaagca aatacagtat caaactaaga taacgccctg tatcaagcag cttcacagta
     6901 tcaagcatta ggctggaaaa agttgttaaa cctccgcaaa aacccgtccc cagtgctaaa
     6961 atcaagccct tactagtccc cttatagacc agatagccct tgacaagata aatcaagcag
     7021 aaaattccca gatagttgac aaagagagtg ccccaaggga aatctggact ggctggtaac
     7081 caagtggaaa ctaggtagcg gacaagtccg cccaacatag cagctagaaa aatccctagc
     7141 ggataaaatt gttctttttt catttgatat tttgatcctg ataatcacgc gaacgtttga
     7201 gtatgtccga aaaagtcgcg acaatagtct cctgatagcg cttgtcctct acacgacttc
     7261 taaccttttc aaaaataact gcttctctct tagtatctaa aatcggtttc cctgaagcct
     7321 tcttataagc gacaactcct tcaactaagt gcattcgttc ttctaacagt ttgacaattt
     7381 ggtcgtcgat ttgatcgatt tcttgacgaa taatatctaa atccatacag tctcctcctt
     7441 tatttgaatt attgtatcaa aaagccatca attaggctag taaaatccca actctcgata
     7501 agaaaaatgc actgattgat tacatcagcg cacttttatg cttatcctac tttagcaacc
     7561 aattcttctg cgaattgttc caagcgttca atatcttctt cctcggcaga aagatcaact
     7621 ttaacacact ctgaaccttt ttctgctcct gttgacacaa agacacggtc aaagtcatca
     7681 acagccttac agaattcatc gtagaaggta tctcctgagc cgaccactcc gtagattttg
     7741 ccattcaagt tgagatctgc taggtcttcg tagaagtcca tcatctcatc tggcaattca
     7801 ccatcaccat aagtataggt cgcaacgata gcgatgtctg cttccaagaa gtctgaagcg
     7861 tcaacagttg tacattcatc aacatcaaca tccaagccca agtcacgtaa tttgtctgct
     7921 acaatatctg caatttcttc ggtattaccg gtcatactgg caaatacaat ttttgctaat
     7981 gccatatcgt cctcctcaat ttatctttct ccattatatc acatcttttt cattttaaaa
     8041 ataaaaattc ttgtgctaca atgaaatgag aaagaattga ggttatttat ggagatttgc
     8101 caacaaattt tagaaaaaat taaagaatac gacaccatta tcattcatcg tcatatgaaa
     8161 ccagaccctg atgccttggg aagtcaggtg ggattaaaag ccttgctgga acatcatttc
     8221 ccagaaaaaa ccatcaaagc cgtcggtttt gatgaaccaa ctcttacttg gatggctgag
     8281 atggatcttg ttgaagatag agcctaccaa ggcgcacttg tcatcgtctg tgatacagct
     8341 aatactgctc gtatcgatga taagcgctat agtcaaggtg attttctcat taagattgac
     8401 caccatccaa atgatgatgt atacggtgac ctgtcttggg tcgatactag ttcaagtagc
     8461 gctagcgaga tgattaccct atttgcccaa acaacccaac tagccttggc agatcgcgat
     8521 gctgagttgc tctttgcagg aattgtcggt gatacaggtc gcttcctcta cccttctacc
     8581 actgcacgga ctcttcgtct ggctgcttat ttgagagaac ataactttga ctttgcggct
     8641 ctcactcgca aaatggacac tatgagctac aaaattgcta aactgcaagg ctacatctac
     8701 gaccatctgg aagtggatga aaatggtgct gctcgcgtta tcctgagtca agaagtcttg
     8761 aaacaataca atgtaaccga tgctgaaact gcagccattg tcggtgcacc tggacgcatt
     8821 gacagagtga gtctctgggg aatttttgtc gaacaggctg atggccacta ccgagttcgc
     8881 ttacgcagta aagtccatcc tatcaatgaa attgccaagg agcatgatgg tggaggccac
     8941 cctctagcaa gtggtgctaa ttcctatagc ctagaagaaa acgaaatcat ctaccaaaag
     9001 ttaaaaaact tgcttaaaaa ctgataaaat acttgccaaa cttttcagaa tctgatagac
     9061 tagtatggta acaatctatg gctcgcaaag agaccatggc agaaaggaaa tattgcaaaa
     9121 tgaaaaaaga tatccatcca gaatatcgcc cagttgtctt catggacaca actactggtt
     9181 accaattcct tagcggttca acaaaacgct ctaacgaaac agttgagttc gaaggcgaaa
     9241 cttacccatt gatccgtgtg gaaatttcat cagactcaca cccattctac actggacgtc
     9301 aaaagttcac tcaagcagat ggacgcgtgg atcgtttcaa caaaaaatac ggtctcaaat
     9361 aatgataaga gaacagtttc ggctgttctt ttttgtttct tgaaatcaac tgctgttttc
     9421 atgttccaga ctcatctgta ggttcggttt ccatgctact aggcaggaag gaaatagctg
     9481 tttcaacacg tccataatga gctgtactat tgtcacgaac cacactttca ttgatggtcc
     9541 aagtggaatt cattttctta aaagcttctc ggactttttc caaatctttg gaggcaatgg
     9601 cctgctctaa ggtttcaaaa cgaggactta gacggtttac caatttttcc ttttccgcat
     9661 ctaggtcaac aggattttgt tctttttcaa aagctaatag agctgaggaa atttcggtga
     9721 gtttggcttc agtaatatct ccagatagag ctaacttttc cttaacaatc ttaccaacct
     9781 cagaatcctt attttctact ctttcgaagt ctgatgccat cttcgtaacg agtttctgga
     9841 cctcagcctg atcaccattt ttaaccgctt tggatgcatc tgtgattttt acgaaataag
     9901 aactcaagct ttcttgggca cctgctgggg aaagaattaa gaattaagaa ttaagaatta
     9961 agaattaaga attaagaatt aagaattaaa aatgacaaag ctaaaacaag caaccagctt
    10021 ttagccttcc aataatttct gaccaatgta gcctcctttc tccacaccac caaagcaagt
    10081 aaaaagtcca ctacctatgt gagtgatgta ttcattcatc ttatcagtag cacctaggtt
    10141 agtttgaacc ttaacaaagt tatcaggatc cttctggaaa gaaatgaaga gcaaacccgt
    10201 atcaaactga ccagtctttt catcaatgcc atctgagtaa gaataagaac gacgtaaaag
    10261 tggcttatcc acttctttgg ccaaacaaac atgcgaatca tcaggtaaga gactcaaatc
    10321 cacttcatca aactcatttt tcttaccaaa gggggcaccg catttctccc cttacggatg
    10381 agattgcgaa tagcgtgaaa ggcaatttgc tcatcatctg cacaagcatg aatcacaata
    10441 tctccaccag tatatttttc acgtaattgc tccttaggaa atagaggtaa atccctgaac
    10501 agtcgagggc gcttgttttc caagttcatc cttttcaaga aacttgcaga tacaccaaaa
    10561 gtcagcgtca aacgatgagg attgagccca actgtcatcc gtccaatcct tgaatagctg
    10621 gataatttta tctctatccg tcgtatgcag gtccaagaca acaaaataga tattcttttg
    10681 catgggcgta ctatttggta catcaagcga accttatgaa aaggtctact gattttaaag
    10741 cgctttcttg tcttcttgaa ttgagatttt atttttagac gcgacaatgg tttgagcgtc
    10801 tgctttctta ggatgttctg gacgtggcat aatatttcgc caaccatggc gcttcaacag
    10861 ttgatagaag gcgtcacgtg tgtaggaacg acctaactcc tttttataag cctgaaataa
    10921 ggcatcaatt gtaacaaatt ctcctgactc tgcagccttc aaatgacggg caagaaaggc
    10981 tttctcttcc tcaactgtca tatatgcatg gttacgacca ctacgtgttt cttgaaggag
    11041 agagtcgagt tcgaactcct catatttttt tacatttcgc taaatcgttg tttgattaca
    11101 gtctaaaagt tctataatct ctttataaga tttgcccatc agacgaaata taataaattg
    11161 aaactagaat agtacacctc tacttctaaa atattattag aaatcgattt g
//
LOCUS       DAVLMQ010000057        10576 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000057 DAVLMQ010000000
VERSION     DAVLMQ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10576
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.057"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..505
                     /locus_tag="VXF95_001810"
                     /pseudo
     CDS             1..505
                     /locus_tag="VXF95_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            405..851
                     /locus_tag="VXF95_001811"
     CDS             405..851
                     /locus_tag="VXF95_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1082315.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFTRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVDHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(989..2293)
                     /gene="eno"
                     /locus_tag="VXF95_001812"
     CDS             complement(989..2293)
                     /gene="eno"
                     /locus_tag="VXF95_001812"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HEV1082316.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2457..2903
                     /locus_tag="VXF95_001813"
     CDS             2457..2903
                     /locus_tag="VXF95_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HEV1082317.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPFGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2900..4015)
                     /locus_tag="VXF95_001814"
     CDS             complement(2900..4015)
                     /locus_tag="VXF95_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HEV1082318.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPFGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASGQSLLNLASVSTENRYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(4024..4669)
                     /gene="serB"
                     /locus_tag="VXF95_001815"
                     /pseudo
     CDS             complement(4024..4669)
                     /gene="serB"
                     /locus_tag="VXF95_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084485.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase SerB"
     gene            complement(4728..6161)
                     /gene="glgA"
                     /locus_tag="VXF95_001816"
     CDS             complement(4728..6161)
                     /gene="glgA"
                     /locus_tag="VXF95_001816"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HEV1082319.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGNQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGLERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6158..7297)
                     /gene="glgD"
                     /locus_tag="VXF95_001817"
     CDS             complement(6158..7297)
                     /gene="glgD"
                     /locus_tag="VXF95_001817"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HEV1082320.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPKK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7287..8429)
                     /locus_tag="VXF95_001818"
     CDS             complement(7287..8429)
                     /locus_tag="VXF95_001818"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HEV1082321.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVTTDED"
     gene            complement(8419..10347)
                     /gene="glgB"
                     /locus_tag="VXF95_001819"
     CDS             complement(8419..10347)
                     /gene="glgB"
                     /locus_tag="VXF95_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HEV1082322.1"
                     /translation="MDNREALKTFMMGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDIYHLDGIRVDAVSNMLYLDYDDAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGGLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNIEDPMNAKMKYFTSQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3222 a         2326 c         1856 g         3172 t
ORIGIN      
        1 gcttatttga ctgaaatagc ttctgaattt ggctgtcatc caactaccat ccactatgcg
       61 ctcaaagcta tgggctacac tcgaaaaaaa gaaccacacc tactatgaac aagacccaga
      121 aaaagtagcc ttatttctta agaattttaa tagtttaaag cacctagcac aggtctaaca
      181 aataaatggt gagttaatcg ctccaatgat ttacgaagag acgatgacga gcgacttttt
      241 tgaagcttgg tttcagaagt ttctcttacc aacattaacc acaccatcgg ttattattat
      301 ggataatgca agattccata gaatggggaa gctagaactt ttatgcgaag agtttgggca
      361 taaactttta cctcttcctc cctactcgcc tgagtacaat cttattgaga aaacatgggc
      421 tcatatcaaa aagcacctca aaagggtatt accaagttgc aatacctttt acgaggctct
      481 tttgtcttgt tcttgtttca attgactata taaattgtct aagcgaaaca accgataaga
      541 attggcacaa aagcgaccgt atttttgtta ccaatacagg aaaaccagtt catagttcta
      601 tcttgagcaa gtctctccag cgagcaaacg aacgccttaa aaaaccaatt cccaaacatc
      661 tgtcccctca catcttcaga cacaccacta ttagcatctt atcagaaaat aaaattcctt
      721 taaaaacaat cacggacagg gttgatcatt ccgactctga agtcactact tccatctaca
      781 cccacgtcac aaagaacatg aaagatgaag caatcaatgt actggataaa gttatgaaaa
      841 agatttttta aaaagttttg tccctttttt gccctctaaa tacaaaaata gcccttcgga
      901 taaaatccga ggggctagaa acgttgttaa atcaacggcc gaacttttga atttcatggt
      961 tcgggataaa atagttcact gaactatttt attttttaag gttgtagaat gatttcaatc
     1021 cacgatattc agctacttca ccaagttggt cttcgatacg aagcaattgg ttgtatttag
     1081 cgatacggtc tgtacgtgaa agtgaaccag tcttgatttg tcctgcgtta gttgcaactg
     1141 cgatatcagc gattgttgaa tcttcagttt cacctgaacg gtgtgataca acagcagtgt
     1201 aaccagcttc tttagccatt tcgatagctt caaaagtttc agtaagagta ccgatttggt
     1261 taactttgat aaggattgag ttagcagcac cttcttggat accacgtgca aggtagtcag
     1321 tgtttgttac gaagaagtcg tcaccaacaa gttgtacttt cttaccaaga cgttcagtaa
     1381 gagctttcca accatcccag tcgttttcat ccataccatc ttcaatagtg atgattgggt
     1441 atttgttaac caattcttca aggtagtcga tttgttctgc agatgtacga acagcagcac
     1501 cttcaccttc aaatttagtg tagtcgtaaa ctttacgttc tttatcgtag aattctgatg
     1561 aagcacagtc aaatccgata aatacgtctt tacctggtac atatccagca gcttcaatcg
     1621 cagcaaggat agtttcaaca ccatcttcag ttccttcgaa acgaggagcg aatccacctt
     1681 cgtcacctac ggcagtttcc aaaccacgtg atttaaggat tttcttaaga gcgtggaaga
     1741 tttcagcacc gtaacgaagg gcttctttaa atgttggcgc accaactggc aagatcatga
     1801 actcttggaa agcaattgga gcgtcagagt gagaaccacc gttgatgatg ttcatcattg
     1861 gagttggaag aactttagtg ttgaatccac caagatagct gtaaagtggg atttcaaggt
     1921 agtcagcagc agcacgagct acagcgatag acacaccgag gattgcattc gcacccaatt
     1981 tacctttgtt aggagtaccg tcaagtgcga tcatagcacg gtcaatagct tgttgatcac
     2041 gtacatcgta gccaatgata gcttcagcaa tgatgttgtt tacgttgtca acagcttttt
     2101 gtgtaccaag accaccgtaa cgagatttgt caccgtcgcg aagttcaact gcttcgtgtt
     2161 caccagtaga agctcctgat ggaaccatac cacgtccgaa agcacctgat tcagtgtaaa
     2221 cttctacttc aagtgttggg ttaccgcgtg agtctaggac ttcgcgagcg taaacatcag
     2281 taataattga cattttttac tctccttatg agttaaattt tttacacctc tataatacct
     2341 taaaacccct cctttttcaa gaaaaaacgt tatctttgtg caacttttcc ttaactttat
     2401 aaagtaatcg ctttcttttg tctgttttat tctaactttt atgatatact gttttcatga
     2461 cagatttatc aaaacaatta cttgaaaaag ctcatggtgg gttaaaaata aatccggatg
     2521 agcaaagacg ctatcttggt acttttgagg aaagagttct tggatatgta gatattgaca
     2581 cagcaaatag ccctcagtta gaaaaaggct ttttatttat tttagaaaac cttcaggaaa
     2641 aagcagagcc actatttgtg aagatttcac caactatcga atttgataag caagttttct
     2701 acttaaaaga agcaaaagaa actgatagtc aagccaccat agtatctgaa gagcatatta
     2761 cttctccttt tggcctggtt attcatagca atgcaccagt tcaagtagaa gaaaaagacc
     2821 ttcgacttgc ttttccaaaa ctttgggaag ttaaaaagga agaaccagcc aaaacatcct
     2881 tatggaagaa atggtttagc taaatcttgc acatatttaa taagtgccca atattggcag
     2941 ccgtgcgctc cagatagaga ctggcatttt tcaaactatc ttctaaaggt tcacttttct
     3001 ccaaaataga aaagacagct tggatatttt caaatggtag gggaggtaaa tcttcagcaa
     3061 gactaccgca aatagcaata acaggaactc caacaggggt tctttttgca acacctatag
     3121 gcgctttccc agcaaagctt tgactatcaa gtcttccttc tccaacaaca accaagtcag
     3181 catctgaaac tttcttatca aaattgatta agtccaagca ggtatcaatt ccagacacga
     3241 tacttgcctg agcaaaggca cacaaaccac cagcaaggcc tccacctgct cctgctcctt
     3301 taatttctaa tgttgcaggt gagaattttt cataaaaatc ttggatcgcc tgatctacta
     3361 ctgcaaacat agtcggatgt agaccttttt gattgccaaa agtgtaagtc gcaccttgat
     3421 gaccacataa gggactcacg acatctgcta aaatatgaat ttgaacacct tcaggaattt
     3481 tatagcgatt ttctgttgaa acagaagcta agtttaataa ggattgaccg gaagcaggca
     3541 agacatttcc atccctatca taaaattgat aacctaaacc agcagcaatc cccagtcctc
     3601 catcattact ggccgtgcca ccaacaccga tataaatatc tttaatccct ttagaaatga
     3661 gatggagaat caactctcca ataccacaag tttggatttg aagtggattt cgtttctcta
     3721 gcggaatttt tccaagacca accaagtcag ctacttcaaa tagtgccagt tccccttttt
     3781 gaaaatagcg catggcttct ttttgtccaa aagggtctgt cacttggatc catttttctt
     3841 ttaggtcaag agaatgtcgg atagcatcta cagtaccttc tcccccatca ccaacagggc
     3901 agaggagaca ttctacatct gctatcgatt gttggaagcc tctttttatt gcttcagcta
     3961 cctgttgagc tgtcaagctt tccttaaacg aatccggtgc aattacaatc ttcatatttt
     4021 ccctcattct aaacagtcaa tcaaaggaag aacttctaaa aaatccctct tgtcaacatg
     4081 atgtggtatt tcttttttga gcatttcttt ggaacaaaag gcgattccta actccgccga
     4141 cttcaacatt aatagattat tgaccccatc accgattgcc accgttcttt ctttagaaag
     4201 ttttagtttc tttctccatt tttccagagt ttcttttttg acctggggac ttataatttg
     4261 tccaactaat tttcctgtta aaagaccttc tttgacttca agctggttgg cagtgaaata
     4321 ggcaatacca agggattttg ctaatctctc caactattgg tgtaaatcca ccaggcacca
     4381 gaccaactag gatgccattc ttttggagaa tagagatgaa ctctgggaca tttagcgata
     4441 gatgaattga gttgaagacg ttatcaaaga ccaaaatagg aagaccttcc aacaaggaca
     4501 ctctttttct taaactgctt tcaaagacca actctcctcg cattgctcga cttgtaatct
     4561 gcgaaatttc cgcctcatga cctgcctctc tccctaaaag atcaatcact tcttctagga
     4621 ttaaggttcc atctacatcc aaaacacaca agccttttac ttgagacatc agttctcctc
     4681 tctaaacagc ctaaaaatcg tatgaagtca tcatacgatt ttatctatta attaactaaa
     4741 ctatggtaca agtcaaggta tgacttgcag gctgtatccc atgagaagtc actctccata
     4801 gcttgttttt gtaggtttct ccaaatgtct ggatggtttc tatacaagtc caatgctgtt
     4861 tggaaagtcc aatttaacca ataaggagat agattgtcaa agctaaagcc agtaccgctt
     4921 ccttcgattg gattgaaagc gcgaactgta tctcgcaagc ctccaacttc atggaccaat
     4981 ggcaaggttc cataacgcat agccatcatt tgagacaagc cacacggttc aaaacgactt
     5041 ggcatgagga agaggtcaca agcagcgtag atttcctgag caagtttgac atcaaaagtg
     5101 atatttgttg atagcttgtc tgggtaaatc tgagcaaacc atgagaaagc tccttcaaag
     5161 gctggatcgc cagttcccaa aagaacaatc tgaacatctt cttgcaagat atggtgaaga
     5221 ctttcgacca ccacatcaaa acctttttga cgtgtcaaac gagaaacaat tcccaccagt
     5281 ggaacgtctg ctctaacagg caagccaact ctttcttgca attttgcctt atttttggct
     5341 ttcccagaca aatcttcctg attgaaatga tagtctaaaa gagcatccgt ctgaggatta
     5401 taaagatcag catcaatccc attcacgata ccagatactt taccagactc cattttaaga
     5461 atctgatcca aattacatcc aaactgacta gtcataattt catgagcata gctaggtgaa
     5521 acggttgaaa cacggttcgc atagagaata cctgccttca tccagttcag acagttgttc
     5581 catcgaaggg tgccatcagc gtaacgttca aggccaactc caaacaaatc acccaacatt
     5641 ccttctgaaa attgtccttg gaattctaaa ttatgaatgg ttaaaactgt ttcaatgtcc
     5701 tcataggctt gaatccaacg gtatttttcc ttcaacaaga aaggaatcat agctgtatgg
     5761 tagtcatgaa catggagaag atcaggaata aagtcaatcc tttccatagc ctcaatggca
     5821 gccagttgga aaaaggcaaa gcgttctccg tcatcaaaat caccgtaaac atgaccacgg
     5881 aagaaataat attgattgtc aataaagtag aaggttacac catttaatac tgttttctta
     5941 attccacaat actgtctgcg ccaaccaacg ctcacctcaa aatgaagcac atcttcaatc
     6001 tgatttccaa atttagcctc taccatatca tagtagggta aaatcactgc aacttcgtgc
     6061 ccagctttta ccagtgattt tggaagagcg ccaatgacgt ctcccaaacc acctgttttt
     6121 gaaaagggtg caccctctgc tgctacaaat aaaattttca tgaatgaata tcctctgtta
     6181 ctttagcacc tttcttaacc acaactggat gttctgcagt tcctcgaatc acaacaccag
     6241 gctcaacttc aacccctttg tccaagatag catattcgac ctgagcccct tctccaataa
     6301 caacacgagg gaagagcagg ctatctttaa ccaagctatc cttatggaca tgaatattac
     6361 gtgatagaac agaattagct acttgacctt caataatact accagaggca aactgagaag
     6421 tgcttacctt agatgtatta gcatagtaag ttggctcttc gtttttgacc tttgtataaa
     6481 tcttttggtt tggtgagaaa agagaataga atttttgtga ttcaagcata tcgatattcg
     6541 cttgataata agatttaaca gagtgaatat tggctagata gcccgtgtac tcgtaggcga
     6601 aagctccctc ttttacagcc aaatcccgta aaacatagcg caatttcttt ggatgttctt
     6661 ttttagcttc ttcttccaag tgttcaatca accaaggtgt atcaacgaca aagatatctg
     6721 tagacatatt gaacgtttca gctgttgact tgctatcaaa gagtttatga gaaagaacat
     6781 ggtctgtttc atctacatcc aagattgcat ttacttctga aatatctttc ttagctagtt
     6841 ttttataaac tacagtgata ggctcttttg ttgtactatg taggtggaaa acttggttca
     6901 aatcaatgtt aataagaaca tcgcagttga gggcaaccgt ttggtttgag ccagaacgtt
     6961 tcaaataagt aagaagctgt tggtagtatt cttttccaac tgtactactt tctacacggg
     7021 tattgtaaat tcctagatag taatgactaa gaagggttga taaaccccac tcgcgtcctg
     7081 aacgaatatg gtcaaatact gagctgatat tatcctgctg gaaaatacca aagacactac
     7141 gaacacctgc attagcaagg cttgaaagtg ggaagtcaat caaacgatat ttcccaccaa
     7201 atggcaaact tgctactgga cggtggtccg tcaatgtcga catattgtga aaaccaactg
     7261 tatttcctaa aatggcagaa tatttatcaa tcttcatctg ttgttacccc cactacttca
     7321 ttatatccta caacttgtac ttcatctgtt ccatcaattt cgacaccgtc agaaataatc
     7381 gcaccttcac caataatggc acgtttaatc ttagctcctt gaccaatgat agctccactc
     7441 atgataactg aatcaaggac ttccgctcct tcgcgaactt gcgcgcctgt tgaaaggata
     7501 gaatgtttaa cagttccatc aacgaaacat ccgtctacaa ctaatgagtc ttctacatga
     7561 gcatttgccc cgaggaagtt tggtggtgaa atcaagtttc ttgagtaaat cttccattga
     7621 cggttacgac tatccaaggc attttctgga gaaatatact ccatgttcgc ttcccaaagt
     7681 gactcaatag taccaacatc tttccaataa ccactaaatt cgtaagcata aacactttca
     7741 cctgactcaa ggtaatttgg aatgacattt ttaccaaagt ctgacatgcc aaccttgctc
     7801 ttttcagcag cgactaacat attacgaagg cgttgccaat caaaaatgta gattcccata
     7861 gaagcttttg tagatttagg ttgagctggc ttttcttcaa attcaacaat acgattgtta
     7921 gcatctgtgt tcatgatacc aaaacggctt gcttctttaa gagggacgtc taaaactgct
     7981 actgtcaagc tggcattatt atccttatga gactggagca tatcatcata gtccattttg
     8041 tagatgtgat ccccagacaa aatcaagaca tactcaggat tgacactgtc gatatagtcg
     8101 atattttggt aaatagcgtg actagtcccc tcaaaccaac gatttccttc acttgcagaa
     8161 taaggttgaa gaatagagac acctgaatta ataccgtcta gtccccagct tgaaccattc
     8221 ccaatatggt tgttgagagc aagtggttga tactgtgtaa cgaccccaac attatgaatc
     8281 cctgagttgg cacagtttga tagggcaaag tcaatgatac ggtagcgccc accaaattgc
     8341 acagctggtt ttgcgatgct ttgagtgagt ttaccgagac gagttccttg cccaccagca
     8401 agaatcaaag ctaacatttc atttttcatt ttctactcct ttttggtttt tatttgtgac
     8461 ggttttagta gatttcaagc gacgtttgat tttccataca cttgctccca tagccggtag
     8521 agtaaaggtt aaggtctgct cataatcttt ccatagtcct tcttgcgttt gaacagtttg
     8581 attatgttct ttccaaacgc ctccccactc ttccaactca gtattccata cttcttcgta
     8641 aattcctgca acgggtagtc cgattgtaaa atctttccgc tcaacaggta ccatgttaaa
     8701 gatacagact aacatttctc cctttttacc cttacgaata aaggaaagaa cactctggtc
     8761 tcgattatcc gcatcaatga tttcaatacc atcatagctg gtatcgattt cccacagaca
     8821 gcgatgatct ttgtaaaact ggtttagctg agaagtgaaa tacttcatct tagcattcat
     8881 tgggtcttct atgttagacc attccaactg ttcttcagat ttccattcta ggaattgacc
     8941 gtattcgcta cccatgaaga gcaatttctt accagggtga caaatttggt acgtatagag
     9001 attgcgcaag cctgcaaatt gattgtaacg atctccccac atcttatgca tcatactctt
     9061 cttgccatga accacttcat cgtgcgagaa tggcaagaga taattctcct tgaaaacata
     9121 cataaagctg aaagtcacca ggttaaagtc atatttacga taaatcggat cttcttcgta
     9181 gaaacggagg atatcattca tccagcccat gttccatttg tagtcaaatc ctagaccacc
     9241 aatctctttc attcccgtaa tcttggttgc agacgaactt tcttctgcaa tcatcatcac
     9301 atctggatat tctaacttaa taacttcatt caagcgttga aggaaataat aaccttcata
     9361 gttgagattt ccgccatctt tattaggtgt ccatggagca tcatcatagt ccaaatagag
     9421 catgttgcta acagcatcca cacgaatacc atccaaatga tagatatcaa tccaatgctt
     9481 aatgcaagaa attaagaagg actggacttc attttttcca aggtcaaaat taagggcacc
     9541 ccaaccatgg ttatgagcct tattatggtc ttggtattca aaagtcggtg tcccatcata
     9601 ataggctaag gcatcatcat tgatggtaaa gtgacctggt acccagtcca caataacccc
     9661 aatattatgg gtatgacact cctcgacaaa atcttgaaac tcctctggtc taccataggc
     9721 atgctctaaa gcgaagtaac ccataagctg gtacccccaa ctcaaaccta gtgggtggga
     9781 catcaagggc ataaactcaa tatgagtata gttcatctca actaggtaag gaatgagttc
     9841 atctttcaat tgggcaaaac tataaggact gccatcagaa tttcttttcc atgatccagc
     9901 gtgaacttca taaatattga caggacgctc ttcaaagccc caacgttttc ttcgtgccag
     9961 ccaaagtcca tccttccatt tcttctcagg aagctctgtt aagattgccc ctgttcctgg
    10021 acgagcctca tacctgacag caaaagggtc aatcttcatc agttgatgac cattttgacg
    10081 tgtgacatga tatttgtaaa tatgcccttc ttgagccata ttggtaaaga cttcccagac
    10141 cccaaaatca tttcttacca ttggaatctg attttcaatc cagttggtaa aatcaccaac
    10201 caagtgaaca gcctgagcat taggtgccca aacacggaag gtatagccat gctctccatt
    10261 tagttcttcc ctatgtgctc ctagataatg ttggagataa aaattttcac ccatcataaa
    10321 ggtttttaat gcttctctat tatccatata ctccctttct cctgtaagcg ttttctatgt
    10381 ttttattata ctaccttttt agagaagatt caagtaaatt actatacttc tttaattatt
    10441 ttgaaaatct acaacaagtt cacttactcg ttcaattgta aatcaatatt ttttcaaaaa
    10501 attgcgaaaa cacctttctt tttctactat agtgaaatga aataaaacat gcgcaaatcg
    10561 attaaggaat ttaatc
//
LOCUS       DAVLMQ010000058        10219 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000058 DAVLMQ010000000
VERSION     DAVLMQ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10219
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.058"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            87..1262
                     /gene="mutY"
                     /locus_tag="VXF95_001820"
     CDS             87..1262
                     /gene="mutY"
                     /locus_tag="VXF95_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HEV1082323.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNFGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            1317..2021
                     /locus_tag="VXF95_001821"
     CDS             1317..2021
                     /locus_tag="VXF95_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1082324.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            2014..3363
                     /gene="vicK"
                     /locus_tag="VXF95_001822"
     CDS             2014..3363
                     /gene="vicK"
                     /locus_tag="VXF95_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HEV1082325.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            3365..4174
                     /locus_tag="VXF95_001823"
     CDS             3365..4174
                     /locus_tag="VXF95_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HEV1082326.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKKKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            4265..4507
                     /locus_tag="VXF95_001824"
     CDS             4265..4507
                     /locus_tag="VXF95_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HEV1082327.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVADLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            4509..4763
                     /locus_tag="VXF95_001825"
     CDS             4509..4763
                     /locus_tag="VXF95_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1082328.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQINVLEDPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            4810..5583
                     /locus_tag="VXF95_001826"
     CDS             4810..5583
                     /locus_tag="VXF95_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HEV1082329.1"
                     /translation="MKKKWFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENVFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLTGKLERKISRFLRTNGLIYILYVNIFIILVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDIVPVSLLGKWLAVLLMLVGIGTIGMLTSALTNFFVKDNPDE
                     QIKLDKLQDELSSPRILLEKQSKKIEELHKMIQDLIEKT"
     gene            complement(5846..6832)
                     /locus_tag="VXF95_001827"
     CDS             complement(5846..6832)
                     /locus_tag="VXF95_001827"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HEV1082330.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            7026..9494
                     /gene="gyrA"
                     /locus_tag="VXF95_001828"
     CDS             7026..9494
                     /gene="gyrA"
                     /locus_tag="VXF95_001828"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001152996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HEV1082331.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIVLRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMVGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEA"
     gene            9494..>10219
                     /gene="srtA"
                     /locus_tag="VXF95_001829"
     CDS             9494..>10219
                     /gene="srtA"
                     /locus_tag="VXF95_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HEV1082332.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQP"
BASE COUNT         3157 a         1731 c         2290 g         3041 t
ORIGIN      
        1 tagatagaaa agttatatac tatctattga aaatattata aatcagatac aaagacaggt
       61 gaaaccttct gtgttatact agagatatgt tagatttgaa agaatacggt atcgtcatgt
      121 ggccggagga gaaagtcatt tctttccgtg agaaacttct cgcttggtat gatgaaaaca
      181 aaagagattt gccttggagg agaagtaaaa atccttatca catctgggta tctgaaatca
      241 tgcttcagca gaccagggtg gatacagtta tcccttacta cgaaagattt ttggactggt
      301 ttccaactgt cgaaagtctg gcaactgcgc ctgaggagag tttactgaaa gcttgggagg
      361 gcttgggtta ttattctcga gttcgcaata tgcaggctgc agcccagcag attatgactg
      421 actttggtgg ccaatttcca aatacctatg aaggaatttc cagcttgaaa gggattggac
      481 cttacacagc aggagccatt tccagtattg cttttaactt gcctgagcca gctgtagatg
      541 gtaatgtcat gcgggtcttg gcgcgtctgt ttgaagtcaa ccacgatatt gggattccaa
      601 gtaatcgaaa aatttttcag gcaatgatgg agatcttgat taatccagat cgtccgggtg
      661 attttaatca agccttgatg gacttagggt ctgatattga gtctcctgta aatcccagac
      721 ctgaagaaag cccagtcaag gactttagtg cggcatatca gaatggaacc atggaccgtt
      781 atccaattaa atctcctaag aaaaagccgg ttcctattta tcttaaagcc ttagttgtga
      841 aaaattctca aggacaattt ttacttgaaa aaaatgaaag cgaaaagctc ttggcaggtt
      901 tttggcattt cccctttata gaagttgata acttttcgca agaagagcag tttgacctct
      961 ttcatcaggt tgcggaagaa agtgtgaact ttggccccag tccagaagag agtttccagc
     1021 aggactatga cctagatgtt gattggcttg atgtttgttt tgatacagtc cagcatgttt
     1081 ttagtcatcg aaaatggcat gtacagattg tagcaggtca ggtgagtgac ttccatgatt
     1141 tttcagatag ggaagttcgt tggctttcac cagaagaatt caagaattac ccacttgcca
     1201 aaccccaaca aaaaatctgg caggcttatg cacaagccaa cttagacagt agccaagact
     1261 agctattgtg tcttctgact attttttggt ataatagtag agaaaaaggt gaacatatga
     1321 aaaaaatact aattgtagat gatgagaaac caatctcgga tattatcaag tttaatatga
     1381 ccaaggaagg ttacgaagtt gtaactgctt ttaatggtcg tgaagcgcta gagcaatttg
     1441 aagcagagca accagatatt attattctgg atttgatgct tccagaaatt gatggtttag
     1501 aagttgctaa gaccattcgt aagacaagca gtgtgcccat tcttatgctt tcagccaaag
     1561 atagtgaatt tgataaggtt atcggtttgg aacttggggc agatgactat gtaacaaaac
     1621 ccttctccaa tcgtgagttg caggcgcgtg ttaaagctct tctgcgtcgt tctcaaccta
     1681 tgccagtaga tggtcaggaa gcagatagta aacctcaacc tatccaaatt ggggatttag
     1741 aaattgttcc agacgcctac gtggctaaaa aatatggcga agaactagac ttaacccatc
     1801 gtgaatttga gcttttgtat catttagcat cgcatacagg tcaagtcatc acgcgcgaac
     1861 acttgcttga gactgtctgg ggttatgact attttggtga tgtccgtaca gttgatgtga
     1921 ctgtacgacg tctgcgtgag aagattgaag atacgcccag ccgaccagag tatatcttga
     1981 cgcgccgtgg tgtagggtat tacatgagaa ataatgcttg atttactgaa acaaaccatt
     2041 tttaccagag attttatctt tatcctgatt ttgttaggtt tcatccttgt tgtgaccctc
     2101 ttattactgg aaaatagacg tgataatatt cagttgaagc aaatcaatca aaaggttaaa
     2161 gatttgattg caggagatta ttccaaggtt cttgatatgc aaggtgggtc tgaaatcacc
     2221 aatattacca ataatttgaa tgacttgtcg gaggttattc gtctcactca ggaaaatcta
     2281 gaacaagaga gtaagaggct aaatagtatt ctgttttata tgacagatgg ggttcttgcg
     2341 accaaccgtc ggggtcagat tatcatgatt aacgatacag ccaagaagca actggggttg
     2401 gttaaggaag atgttctgaa tagaagcatt ttggaattgc tcaagataga agaaaactat
     2461 gaattgcgtg atttgattac ccaaagtcca gaattgttgc tagattccca agatatcaat
     2521 ggcgaatatt tgaaccttcg agttcgcttt gccttgatac gtcgagagtc tggctttatt
     2581 tcaggtttgg tggctgtttt gcatgatacg acggagcagg agaaggaaga acgcgaacga
     2641 agactctttg tttccaatgt tagccatgag ttacggactc ctctgactag cgtaaaatcc
     2701 tatcttgaag ccttggatga gggggctttg tgtgaaactg tagcaccaga ctttatcaag
     2761 gtttctcttg atgagaccaa ccgtatgatg cgcatggtga cggatctcct ccatctttca
     2821 cgtattgata atgctaccag tcacctagat gtggaactga ttaacttcac tgcttttatt
     2881 acctttatcc tcaatcgttt tgacaagatg aaaggacagg aaaaggagaa aaaatatgag
     2941 ttggtgagag attatcccat caattctatc tggatggaaa ttgatacaga taagatgacg
     3001 caggttgtcg acaatatttt aaataatgct attaagtatt cgccagatgg gggtaaaatc
     3061 actgtcagaa tgaagacaac tgaagaccag atgattttat ccatttctga ccacggtttg
     3121 gggattccta agcaggattt accacgtatc tttgaccgtt tctatcgtgt ggatcgtgct
     3181 agaagtcgtg cacaaggtgg tacaggtcta ggactgtcta tcgctaaaga aattatcaaa
     3241 caacataagg gctttatttg ggccaagagt gaatacggca agggttcaac ctttaccatt
     3301 gtgctccctt atgataagga tgcagtgaaa gaagaagtat gggaggatga agtagaagac
     3361 tagaatgagt gaaataggct ttaaatacag tattttagcg tcgggttcca gtggaaattc
     3421 tttttatctg gaaacctcaa aaaagaagct tttagtagat gcaggcttgt ctggcaagaa
     3481 aattaccagt ctgctagctg aaattaaccg taagccagaa gacctggatg ccatcttgat
     3541 tacccatgag cattcagatc atatccatgg agtaggcgtt ttggctcgca agtatggtat
     3601 ggatctttat gccaatgaaa agacctggca agctatggaa aatagtaaat atcttggcaa
     3661 ggtggattct tcgcaaaagc atatttttga aatgggtaaa accaaaacct ttggagatat
     3721 cgacatcgag agttttggtg taagccatga tgcagtcgca ccgcagttct atcgctttat
     3781 gaaggatgat aagagttttg tccttttgac agatacaggt tatgtcagtg accgtatggc
     3841 gggcattgtc gaaaatgcgg atggctatct tatcgaggcc aaccatgatg tagagatttt
     3901 gcgatcaggt tcttacgctt ggcgactcaa acaacgaatc ctatctgacc ttggtcacct
     3961 ttctaacgag gacggtgctg aagctatgat tcggacgcta ggaaatcgta ctaagaagat
     4021 ttaccttggg catttatcta aggaaaacaa tatcaaggaa ctggctcata tgaccatggt
     4081 caatcagctg gctcaagctg atctgggagt cggagtagac tttaaggttt atgatacctc
     4141 accagatacc gcaacaccat tgacagagat atagaaagaa cgctgagaag gtgttctttt
     4201 tatattgact gaacacctaa aaagtaatac aatggtgtta ccattaaaaa agggagcaca
     4261 aaagatgact actattacat taaaagtttc tgaagctgat aaaacattta tgaaagcaat
     4321 ggctaagttt gaaggagttt ccctttcgga acttattcgc accaaaactc ttgaagccct
     4381 agaagatgaa tacgatgctc gtgtggcaga tttagcctat caagagtatt tagaagactt
     4441 ggaaaaagga gttgaaccca ttacttggga agaaatgatg catgatttag gcttgaagga
     4501 tgaataattt gtataaatta gttccaacaa gacgtttcat caagcaattg aaaaaattgg
     4561 accgttatac gcagaagcta attacaaact atttacaaat caatgttttg gaagacccaa
     4621 gacgacacgg aaaggctttg gttggtaatc gcgttggtca atggcgctat agaattggta
     4681 attatcgagt tatcgtacaa attgtagatg atgaattagt tgttgctact ctagaagttg
     4741 gtcatcggag agatatttat tgaattaaag ctgagtaata acaatataga aagtaaggag
     4801 agtaaaaatt tgaagaaaaa atggtttttt gcagattatt atgatacaac aattatttta
     4861 cttgctttaa tctctgttat tctggtatta cttggatttg ctgagatgat tgatttggac
     4921 aatccgcctt atagtattat tgatttagta atctggggtg tttttgtaat tgattatagt
     4981 tggcgctttt ttattactaa aagaaaatgg cgctttattc ttgaaaatgt ttttgattta
     5041 ttggctattc tccctttaaa tgctattttc acagtttttc gattagggcg tatctttcgt
     5101 ttagttaaac taacaaaatt actgaaactg actcgtttac ttagaataat tggacttaca
     5161 ggtaaattag aaagaaaaat tagtagattc ttacggacaa atggcctgat ttatatctta
     5221 tatgttaata tctttattat tctagtagga agttcaattt tatctgtagt tgaagaaaaa
     5281 tccttctcag atagtctttg gtgggctctt gtgacagtaa ctactgttgg ttatggtgat
     5341 attgttccag tttccctttt ggggaaatgg ctagcagttt tactgatgct tgtcggtatt
     5401 ggaacaatag ggatgttaac aagtgctttg acgaactttt ttgtaaagga taatccagat
     5461 gaacagataa aacttgataa actccaagat gaattatcta gtccgagaat attactagag
     5521 aaacaatcta aaaagataga agaactacat aaaatgatac aagatttgat tgaaaaaaca
     5581 taataaaaat aaagatgaga aaaagtttga actgaggaga aatcaagtaa gttttgacac
     5641 aatagaacgc atattatcag gtataaaaac ttgatattat gcgttttatt gtgggaagat
     5701 gtataatgga ttgaaataag atatgaacaa atcgattagg aatttaaagc attttataac
     5761 aacgttttag agtaacgggg tactatttca tataatacag gaaaaaacaa ctccctgatg
     5821 attcaaggag ttgtctatag ttaaattagt ttttagaagc ttcttggaat tctggatttt
     5881 tccatgcttc gtcaataata gcttgcaatt ctttagcaga tgcttgcatt ttttgagttt
     5941 ctgcatcgtt caatggaatg tttactggac gaacgatacc atgtgcacca acaacagctg
     6001 gttgaccgat aaagacattc tcaactccgt attgaccttc ttggaatact gaaagtggaa
     6061 gtactgcgtt ttcatcgtca aggattgctt tagtgatacg agcaagggct actgcgatac
     6121 cgtagtatgt tgcacctttt ttgttgatga ttgtgtaggc tgcatcacga acaccttcga
     6181 acaattcaat caattcagct tcttgaacat tttgagtgtc tttaaggaat tcttcaaggt
     6241 ttacaccagc gatgttagcg tgtgaccaaa cagcgaactc agagtcaccg tgttcaccca
     6301 tgatgtaggc gtgcactgaa cgagcatcca catccaattt ttcagcaagt gcttgacgga
     6361 aacgagctga gtcaagtgaa gtacctgaac cgataacgcg ttctttaggg aaaccagaga
     6421 atttccaagt tgagtaagtc aaaacgtcaa ctgggttagc agcaacaagg aagatacctt
     6481 tgaaaccaga ttcaacaact tgagttacga ttgatttgtt gatagcaagg tttttaccta
     6541 caaggtcaag acgagtttca cctggttttt gaggtgcacc tgcagtgatc acaacaaggt
     6601 cagcgtctgc acagtcagag tattgagctg catagatttt tttaggtgaa gtgaaggcaa
     6661 gggcgtgact aaggtcaagc gcatcaccaa cagctttttc atgcaattgt ggaatttcga
     6721 taattccaag ctcttgtgca attccttggt taacaagtgc aaaagcgtaa gatgaaccta
     6781 cagcaccatc accgacaagg ataacttttt tgtgttgttt agttgaagtc attgttttaa
     6841 acatctcctt aattttatta ggggattttc cctagacaac ttcattctat cacttttaaa
     6901 aaactttgtc acgaatatgc cttatagttc tcgatgtaaa cgttttagtg gtttagaggc
     6961 tgaaatagat gggaatttat ggtataatgt tgttacttac taattgtgaa atgaggcatt
     7021 tattaatgca ggataaaaat ttagtgaatg tcaatctgac aaaggagatg aaggcaagtt
     7081 ttatcgacta cgccatgagt gttatcgtag cgcgagctct tcctgatgtt cgagatggct
     7141 taaaacctgt tcaccgtcgc attctctacg gaatgaatga attgggtgtg accccagaca
     7201 aaccccataa aaaatctgct cgtattacag gggatgtcat gggtaaatat cacccacacg
     7261 gggattcctc tatttatgaa gccatggtcc gtatggctca atggtggagc taccgttaca
     7321 tgcttgtaga tggtcatggg aattttggtt ccatggatgg agatagtgct gccgctcaac
     7381 gttataccga ggcacgtatg agcaagattg ctctggaaat gcttcgtgat atcaacaaaa
     7441 atacagttga tttcgttgat aactatgatg ccaatgaacg ggaacccttg gtcttgccag
     7501 cgcgttttcc aaaccttttg gttaatggag caactggtat cgcggttggg atggcaacca
     7561 atattccacc tcataatctg ggtgaaacca ttgatgcagt gaagttggtc atggataatc
     7621 ctgaagtgac taccaaggac ttgatggaag tcttgcctgg accagatttt ccaactggtg
     7681 ctcttgtcat ggggaaatca ggtatccata aggcttatga aacaggtaaa ggttcgattg
     7741 tcctacgttc tcgtacagag attgaaacga ctaagactgg tcgtgagcgt atcgttgtaa
     7801 cagaatttcc ttacatggtc aataaaacca aggtgcatga gcatattgtt cgcttggttc
     7861 aggaaaaacg cattgagggt atcacagcag tacgtgatga gtcaaaccgt gaaggtgttc
     7921 gatttgttat tgaagtcaag cgcgacgcct cagccaatgt tattctcaat aacctcttca
     7981 aaatgaccca aatgcaaacc aattttggtt tcaatatgct cgctatccaa aatggtatac
     8041 cgaaaatttt gtctcttcgt cagattttgg atgcttatat cgagcaccaa aaagaagtgg
     8101 ttgttcgtcg tacacgtttt gataaggaaa aagcggaagc gcgcgctcat atcttagaag
     8161 gtctcttgat tgcgctagac catatcgacg aagtgattcg tatcatccgt gctagtgaaa
     8221 cggatgcgga agctcaagct gagttgatga gcaagtttaa gctttctgaa cgtcaaagtc
     8281 aagctatcct tgatatgcgt cttcgtcgtt tgacaggttt ggaacgcgat aagattcaat
     8341 ctgagtatga tgacctcttg gctctgattg cggatttagc agatattctt gctaagcctg
     8401 aacgtgtttc tcaaattatc aaagacgaat tggatgaagt taaacgtaaa ttttctgata
     8461 aacgccgtac agagttgatg gttggacagg tcttgagtct cgaggatgag gacttgattg
     8521 aagaatcgga tgtcttgatt accctttcta acagaggcta cattaagcgt ttggatcagg
     8581 acgagttcac tgctcaaaaa cgtgggggtc gtggtgtcca aggaacggga gtgaaagatg
     8641 atgactttgt tcgtgagtta gtgtcaacta gtacccatga tcatctgctc ttcttcacaa
     8701 acaagggacg tgtctatcgt cttaaaggtt atgaaattcc tgagtatggt cggactgcca
     8761 aagggctacc agtagtcaat ctcttgaaat tggatgaaga cgaaagtatt cagacggtta
     8821 tcaatgttga gtctgatcgc agtgatgatg cttatctctt ctttacaacc cgtcacggta
     8881 ttgtgaagag aaccagtgtt aaggagtttg ccaatattcg tcaaaatggt ctcaaagcgc
     8941 tgaatttaaa ggatgaagat gagttaatca atgtcttgtt ggcagaagga gatatggata
     9001 ttatcattgg taccaagttt ggttatgcag ttcgctttaa tcaatcagcc gttcgtggta
     9061 tgagccgtat cgccactggt gtgaaaggtg ttaaccttcg tgaaggagac acagttgttg
     9121 gtgccagctt gattactgat caagatgagg ttcttattat cacagaaaaa ggatatggta
     9181 agcgtacagt cgctactgaa tacccaacaa aaggtcgtgg tggtaaggga atgcagacag
     9241 ctaaaattac cgaaaaaaat ggcttgctgg ccggtcttat gactgttcaa ggggatgagg
     9301 atttgatgat tatcactgat acaggtgtca tgattcgaac caatcttgcc aatatttcac
     9361 aaacaggacg tgcaactatg ggagttaaag taatgcgcct ggatcaagat gctcagatag
     9421 tgactttcac aacggttgcg gtggcagaaa aagaagaagt tgggacagaa aacgaaacag
     9481 aaggtgaagc ataatgtctc aaaaaaataa taaaaagaaa aacaagcgaa aaaatctgct
     9541 gacaaatatc ctagcaggat ttctgatatt actgtcactg gctttgattt ttaatactca
     9601 aattcgaaat attttcatag tctggaatac caataagtat caagttagcc aggtatcaaa
     9661 agaaaaatta gaagaaaatc aggatacaga aggcaatttt gactttgatt ctgtcaaagc
     9721 tatctcttcg gaagctgttc taacttctca atgggatgct caaaaattac cagttattgg
     9781 gggaattgca attcctgaat tggaaatgaa tttgccgatt tttaaaggac ttgataatgt
     9841 taatctcttc tacggagctg gtacaatgaa acgcgagcaa gtaatgggag aaggaaatta
     9901 tagtctagct agtcaccata tctttggtgt tgataatgct aataaaatgt tattttctcc
     9961 tttagataat gctaaaaatg gcatgaagat ttatctaacc gataaaaata aagtttatac
    10021 ttatgaaata cgtgaagtca aacgtgtgac accggatcgt gttgatgaag ttgatgatag
    10081 agatggggtc aatgaaatca cattagtaac ctgtgaagac cttgctgcta cagaacgtat
    10141 tattgtcaaa ggtgatttga aagaaacaaa agattattca caaacatctg atgaaatcct
    10201 aacagctttc aatcaacca
//
LOCUS       DAVLMQ010000059        10083 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000059 DAVLMQ010000000
VERSION     DAVLMQ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10083)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10083)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10083
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.059"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            160..5139
                     /locus_tag="VXF95_001830"
     CDS             160..5139
                     /locus_tag="VXF95_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HEV1082333.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFAGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHARENKLEKAEGVAIASETASPASNEAATTE
                     TAEAASAAKPEEKASEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEK
                     EVQPDVPKNTEKTLKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNE
                     KASKEAKVQALSNTNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDA
                     GHRNGVPVYGTLFFNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFI
                     NQETTGDLVKPLGEKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYN
                     YQFMQPEGDKVPADNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKT
                     KVKWNDILDENGKLRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGD
                     KDWYGIANLVADRTPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWR
                     WWQTSTGEKLRAEYDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVA
                     HKGGKGSKVYMAFSTTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFF
                     EHEGAVKDYQFNLGQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADF
                     YEVYEKDGDSWKLLTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTT
                     FDWGMTVKDTSLPKPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSA
                     QLSGSVDIRLTKPRTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEV
                     RGNKAHVTDITLDKPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMA
                     KAAARSLGNNKVQVGFADVPAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQ
                     SGLLYYRTQLPGKEISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLR
                     VQYEGGTEDELIRLTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEAS
                     PKTILGIEVSQEPKKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQK
                     TGRQTLTLHYQGHEVSFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASSEVKEA
                     FLKAIEAAEQVLKDHETSTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQ
                     ELLAAKPNHPSGSALAPLLEKNKALVEKVDLSPEELATAKQSLKDLVALLKEDKPAVF
                     SDSKTGVEVHFSNKEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVD
                     LSYASIVKIPIEKDKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESA
                     EKPQPAKPAPQNKVLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRV
                     IIQGRDGLLRHVFEVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQ
                     NTAVKSEEASKQLPNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            5229..6425
                     /locus_tag="VXF95_001831"
     CDS             5229..6425
                     /locus_tag="VXF95_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HEV1082334.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADNVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            6561..7088
                     /locus_tag="VXF95_001832"
     CDS             6561..7088
                     /locus_tag="VXF95_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HEV1082335.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFCFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            7165..7521
                     /gene="glnR"
                     /locus_tag="VXF95_001833"
     CDS             7165..7521
                     /gene="glnR"
                     /locus_tag="VXF95_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HEV1082336.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            7558..8904
                     /gene="glnA"
                     /locus_tag="VXF95_001834"
     CDS             7558..8904
                     /gene="glnA"
                     /locus_tag="VXF95_001834"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HEV1082337.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(8994..9113)
                     /locus_tag="VXF95_001835"
     CDS             complement(8994..9113)
                     /locus_tag="VXF95_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HEV1082338.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
     gene            9371..9508
                     /locus_tag="VXF95_001836"
     CDS             9371..9508
                     /locus_tag="VXF95_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082339.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            9601..10083
                     /locus_tag="VXF95_001837"
                     /pseudo
     CDS             9601..10083
                     /locus_tag="VXF95_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
BASE COUNT         3268 a         1817 c         2174 g         2824 t
ORIGIN      
        1 tttaacctta ttttagattt gtgcaaacag ttattgtttt ttgtctaaaa atgttttagg
       61 ataaaaatgt gattatcatg gttctagagt ttgataaaaa actacagaat ataaagcact
      121 ttcttgaaaa caacaaaatc aatcttttag gaggagaaaa tgaagaatcc attttttgaa
      181 agacgttgtc gttacagtat tcgtaagtta tcagtaggag cctgctcgct gatgattggt
      241 gctgttttat ttgctggtcc agccttggct gaagaaactg cagttcctga aaatagcgga
      301 gctaatacag agcttgtttc aggagagagt gagcattcga ccaatgaagc tgataagcag
      361 aatgaagggg aacatgctag agaaaacaag ctagaaaagg cagaaggagt agcgatagca
      421 tctgaaactg cttcgccagc aagcaatgaa gctgcaacta ctgaaactgc agaagcagct
      481 agcgcagcta aaccagagga aaaagcaagt gaggtggttg cagaaacacc atctgcagaa
      541 gcaaaaccta agtctgacaa ggaaacagaa gcaaagcccg aagcaactaa ccaaggggat
      601 gagtctaaac cagcagcaga agctaataag actgaaaaag aagtccagcc agatgtccct
      661 aaaaatacag aaaaaacatt aaaaccaaag gaaatcaaat ttaattcttg ggaagaattg
      721 ttaaaatggg aaccaggtgc tcgtgaagat gatgctatta accgcggatc tgttgtcctc
      781 gcttcacgtc ggacaggtca tttagtcaat gaaaaagcta gcaaggaagc aaaagttcaa
      841 gccttatcaa acaccaattc taaagcaaaa gaccatgctt ctgttggtgg agaagagttc
      901 aaggcctatg cttttgacta ttggcaatat ctagattcaa tggtcttctg ggaaggtctc
      961 gtaccaactc ctgacgttat tgatgcaggt caccgtaacg gggttcctgt atacggtaca
     1021 ctcttcttca actggtctaa tagtattgca gatcaagaaa gatttgctga agctttgaag
     1081 caagacgcag atggtagctt cccaattgcc cgtaaattgg tagacatggc caagtattat
     1141 ggctatgatg gctatttcat caaccaagaa acaactggag atttggttaa acctcttgga
     1201 gaaaagatgc gccagtttat gctctatagc aaggaatatg ctgctaaggt aaaccatcca
     1261 atcaagtatt cttggtacga tgccatgacc tataactatg gacgttatca tcaagatggt
     1321 ttgggagaat acaactacca attcatgcaa ccagaaggag ataaggttcc ggcagataac
     1381 ttctttgcta actttaactg ggataaggct aaaaatgatt acactattgc aactgccaac
     1441 tggattggtc gtaatcctta tgatgtattt gcaggtttgg aattgcaaca gggtggttcc
     1501 tacaagacaa aggttaagtg gaatgacatt ttagacgaaa atgggaaatt gcgcctttct
     1561 cttggtttat ttgccccaga taccattaca agtttaggaa aaactggtga agattatcat
     1621 aaaaatgaag atatcttctt tacaggttat caaggagacc ctactggcca aaaaccaggt
     1681 gacaaagatt ggtatggtat tgctaaccta gttgcggacc gtacgccagc ggtaggtaat
     1741 acttttacta cttcttttaa tacaggtcat ggtaaaaaat ggttcgtaga tggtaaggtt
     1801 tctaaggatt ctgagtggaa ttatcgttca gtatcaggtg ttcttccaac atggcgctgg
     1861 tggcagactt caacagggga aaaacttcgt gcagaatatg attttacaga tgcctataat
     1921 ggcggaaatt cccttaaatt ctctggtgat gtagccggta agacagatca ggatgtgaga
     1981 ctttattcta ctaagttaga agtaactgag aagaccaaac ttcgtgttgc ccacaaggga
     2041 ggaaaaggtt ctaaagttta tatggcattc tctacaactc cagactacaa attcgatgat
     2101 gcagatgcat ggaaagagct aaccctttct gacaactgga caaatgaaga atttgatctc
     2161 agctcactag caggtaaaac catctatgca gtcaaactat ttttcgagca tgaaggtgct
     2221 gtaaaagatt atcagtttaa cctaggacaa ttaactatct cggacaatca ccaagagcca
     2281 caatcgccga caagcttttc tgtagtgaaa caatctctta aaaatgccca agaagcggaa
     2341 gcagttgtgc aatttaaagg caacaaggat gcagatttct atgaagttta tgaaaaagat
     2401 ggagacagct ggaaattact aactggctca tcttctacaa ctatttatct accaaaagtt
     2461 agccgctcag caagtgctca gggtacaact caagaactga aggttgtagc agtcggtaaa
     2521 aatggagttc gttcagaagc tgcaaccaca acctttgatt ggggtatgac tgtaaaagat
     2581 accagcctac caaaaccact agctgaaaat atcgttccag gtgcaacagt tattgatagt
     2641 actttcccta agactgaagg tggagaaggt attgaaggta tgttgaacgg taccattact
     2701 agcttgtcag ataaatggtc ttcagctcag ttgagtggta gtgtggatat tcgtttgacc
     2761 aagccacgta ccgttgttag atgggtcatg gatcatgcag gggctggtgg tgagtctgtt
     2821 aacgatggct tgatgaacac taaagacttt gacctttatt ataaagatgc agatggtgag
     2881 tggaagctag ctaaggaagt ccgtggtaac aaagcacacg tgacagatat cactcttgat
     2941 aaaccaatca ctgctcaaga ctggcgcttg aatgttgtca cttctgacaa tggaactcca
     3001 tggaaggcta ttcgtatcta taactggaaa atgtatgaaa agcttgatac tgagagtgtc
     3061 aatattccga tggccaaggc tgcagcccgt tctctaggca ataacaaggt acaagttggc
     3121 tttgcagatg taccggctgg agcaactatt accgtttatg ataatccaaa ttctcaaact
     3181 ccgctcgcaa ccttgaagag cgaagttgga ggagacctag caagtgcacc attggatttg
     3241 acaaatcaat ctggtcttct ttattatcgt acccagttgc caggcaagga aattagtaat
     3301 gtcctagcag tttccgttcc aaaagatgac agaagaatca agtcagtcag cctagaaaca
     3361 ggacctaaga aaacaagcta cgccgaaggg gaggatttgg accttagagg tggtgttctt
     3421 cgagttcagt atgaaggagg aactgaggac gaactcattc gcctaactca cgcaggtgta
     3481 tcagtatcag gttttgatac gcatcataag ggagaacaga atcttactct ccaatatttg
     3541 ggacaaccag taaatgctaa tttgtcagtg actgtcactg gccaagatga agcaagtccg
     3601 aaaactattt tgggaattga agtaagtcag gaaccgaaaa aagattacct agttggtgat
     3661 agcttagact tgtctgaagg acgctttgca gtggcttata gcaatgacac catggaagaa
     3721 cattccttta ctgatgaggg agttgaaatt tctggttacg atgctcaaaa gactggtcgt
     3781 caaaccttga cgcttcatta ccaaggccat gaagttagct ttgatgtttt ggtatctcca
     3841 aaagcagcat tgaacgatga gtacctcaaa caaaaattag cagaagttga agctgctaag
     3901 aacaaggtgg tctataactt tgcttcatca gaagtaaaag aagccttctt gaaagcaatt
     3961 gaagcggccg aacaagtgtt gaaagaccat gaaactagca cccaagatca agtcaatgac
     4021 cgacttaata aattgacaga agctcataaa gctctgaatg gtcaagagaa atttaaggaa
     4081 gaaaagacag agcttgatcg cttaacaggt gaggttcaag aactcttggc tgccaaacca
     4141 aaccatcctt caggttctgc cctagctccg cttcttgaga aaaacaaggc cttggttgaa
     4201 aaagtagatt tgagtccaga agagcttgca acagcgaaac agagtctaaa agatctggtt
     4261 gctttattga aagaagacaa gccagcagtc ttttctgata gtaaaacagg tgttgaagta
     4321 cacttctcaa ataaagagaa gactgtcatc aagggtttga aagtagagcg tgttcaagca
     4381 agtgctgaag agaagaaata ctttgctgga gaagatgctc atgtctttga aatagaaggt
     4441 ttggatgaaa aaggtcaaga tgttgatctc tcttacgctt ctattgtgaa aatcccaatt
     4501 gaaaaagata agaaagttaa gaaagtattt ttcttacctg aaggcaaaga ggcagtagaa
     4561 ttggcttttg aacaaacgga tagtcatgtt atctttacag caccacactt tactcattat
     4621 gcctttgttt atgaatctgc tgaaaaacca caacctgcta aaccagcacc acaaaacaaa
     4681 gtccttccaa aacctactta tcaaccggct tctgatcaac aaaaggctcc taaattggaa
     4741 gttcaagagg aaaaggttgc ctttcatcgt caagagcatg aaaatgctga gatgctagtt
     4801 ggggaacaac gagtcatcat acagggacga gatggactgt taagacatgt ctttgaagtt
     4861 gatgaaaacg gtcagcgtcg tcttcgttca acagaagtca tccaagaagc gattccagaa
     4921 attgttgaaa ttggaacaaa agtaaaaaca gtaccagcag tagtagctac acaggaaaaa
     4981 ccagctcaaa atacagcagt taaatcagaa gaagcaagca aacaattgcc aaatacagga
     5041 acagctgatg ctaatgaagc cctaatagca ggcttagcca gcctcggtct tgctagttta
     5101 gccttgacct tgagacggaa aagagaagat aaagattaaa tatcgaaaaa tcttgtgaaa
     5161 tctttcctta tatttccaaa gtgtgatata atagttttga ataaaataaa taaaggagtt
     5221 tttgtaacat ggcaaaactt actgttaaag acgttgactt gaaaggtaaa aaagtcctcg
     5281 ttcgtgttga cttcaacgta ccattgaaag atggcgtaat cactaacgat aaccgtatca
     5341 cagcagctct tccaactatt aagtacatca tcgaacaagg tggacgtgca attcttttct
     5401 ctcaccttgg acgtgtgaaa gaagaagctg ataaagctgg caaatcactt gctcctgtag
     5461 cagctgactt ggcagcaaaa cttggtcaag atgttgtttt cccaggtgtc actcgtggtg
     5521 ctgaattgga agcggcaatc aacgctcttg aagatggaca agttctcttg gttgaaaaca
     5581 ctcgttacga agatgttgac ggcaagaaag aatctaaaaa cgatcctgaa cttggtaaat
     5641 actgggcatc acttggagat ggtatcttcg taaacgatgc attcggtaca gctcaccgtg
     5701 cacacgcatc taacgttggt atctcagcaa acgttgaaaa agcagttgct ggtttccttc
     5761 ttgaaaacga aattgcctac atccaagaag cagttgaaac tccagaacgt ccattcgtgg
     5821 ctatccttgg tggttcaaaa gtttcagaca agatcggtgt tatcgaaaac ttgcttgaaa
     5881 aagctgataa cgtccttatc ggtggtggga tgacttacac attctacaaa gcacaaggta
     5941 tcgaaatcgg taactcactt gtagaagaag acaaattgga tgttgcgaaa gctcttcttg
     6001 aaaaagcaaa tggtaaattg atcttgccag ttgactcaaa agaagctaac gcatttgctg
     6061 gttacactga agtgcgtgac actgaaggtg aagcagtttc tgaaggcttc cttggtcttg
     6121 acatcggtcc aaaatctatc gccaaatttg acgaagcttt gactggtgcc aaaacagttg
     6181 tatggaacgg acctatgggt gtatttgaaa acccagattt ccaagctggt acaatcggtg
     6241 tgatggacgc tatcgtgaaa caaccaggag ttaaatcaat catcggtggt ggtgactcag
     6301 ctgccgcagc gattaacctt ggccgtgcag acaagttctc atggattagt acgggtggtg
     6361 gagcatcaat ggaacttctt gaaggtaagg ttcttccagg acttgcagcc ttgacagaaa
     6421 aataagattt tataaataaa tcaaagaaga gagggatgaa agttcctctt ttcttttgct
     6481 taaaataaaa acgcttcctc tcaactatta ctcataaaaa tcaccgattt atgataaaat
     6541 ggaaatagaa agttgagatt atgagttatt ttaaaaaata taaattcgat aaatcccagt
     6601 tcaaacttgg tatgcgaacc tttaaaacag gtattgctgt ttttctagtt ctcttgattt
     6661 tttgcttttt tggctggaaa ggtcttcaaa ttggtgcttt gacagccgtt tttagcctga
     6721 gggagagttt tgatgagagt gttcattttg ggacttcgcg tattctagga aatagtatcg
     6781 gtggactcta tgccttggtc ttcttcttat taaatacctt tttccacgaa gccttttggg
     6841 tgaccttggt agttgttcca atctgcacca tgttaaccat tatgacaaat gtagcaatga
     6901 ataacaaagc aggggttatt ggtggtgtag cagctatgtt aatcattacc ctatcaattc
     6961 caagtggtga gacaatttcg tacgtgtttg tgcgtgtatc agaaacgttt atgggagttt
     7021 ttgtcgcaat tatcgtaaat tacgatattg atcgtattcg tctcttttta gagaaaaaag
     7081 aaaaataatg ttacatttta taacattatc aattgacgtt tgtctttttt tagactataa
     7141 tagacagaaa gaaggaaatt gtaaatgaag gaaaaagaat ttcgccgaaa tatggctgtt
     7201 tttcctatcg gcagtgttat gaagttgacc gatctatcgg cgcgtcagat tcgttattat
     7261 gaagatcaag agttgatcaa gcccgatcga aacgaaggaa atcgtcgcat gtattccttg
     7321 aatgacatgg atcgtctgct tgaaatcaaa gattatatct ctgaaggtta taatatcgct
     7381 gccattaaga aaaaatatgc tgaacgtgaa gcgaaatcca agaaagcggt tagtcagact
     7441 gaagtacgtc gtgcacttca caatgaactc ctccaacagg ggcgttttgc ttcagtacag
     7501 tcaccttttg gtcgcggtta ggcaaccgca agtagtcata gattaaggag aaaacttatg
     7561 ccaatcacag ctgcagatat tcgtcgtgaa gtcaaggaaa aaaatgttac ctttattcgt
     7621 cttatgttct cagatatttt gggaaccatg aaaaacgtcg aaattcctgc tacagatgaa
     7681 cagttagata aggtcttgtc gaacaaggtt atgtttgatg gatcttctat tgaaggtttt
     7741 gtacgtatca atgagtcgga tatgtacttg tacccggact tggatacatg gacagtcttc
     7801 ccttggggag atgaaaatgg aagtgttgca ggtctgatct gtgatgttta tacaacagaa
     7861 ggtgaaccat ttgcgggtga ccctcgtggt aatttgaaac gagctcttcg tcacatggaa
     7921 gaagttggat tcaaatcctt caaccttggt ccagagccag aattcttcct atttaagttg
     7981 gatgaaaatg gggacccaac acttgaagtg aatgacaagg gtggctactt tgatttggca
     8041 cctactgacc ttgcggacaa cacacgtcgt gagattgtga atgtcttgac caaaatggga
     8101 tttgaagtag aagcgagtca ccacgaggtt gcggttggac agcatgagat tgactttaag
     8161 tacgatgaag ttctccgtgc ttgtgataag attcaaatct ttaaacttgt tgttaaaacc
     8221 attgctcgca aacacggact ttacgcaaca tttatggcga agccaaaatt tggtattgct
     8281 ggctcaggta tgcactgtaa tatgtccttg tttgatgcag aaggaaataa cgccttcttt
     8341 gatccaaatg atccaaaagg aatgcagttg tcagaaacag cttaccattt cctaggcggt
     8401 ttgatcaagc atgcttacaa ctatactgcc atcatgaacc caacagttaa ctcatacaaa
     8461 cgtttggttc caggttatga agcgcctgtt tacattgctt gggctggtcg taaccgttcg
     8521 ccacttgtgc gcgtacctgc ttcacgtggt atgggaactc gtcttgagtt gcgttcagtg
     8581 gatccaatgg cgaaccctta cattgctatg gctgttcttt tggaagttgg tttgtatggt
     8641 attgaaaata aaatcgaagc accagctcct atcgaagaaa atatctacat catgacagca
     8701 gaagagcgca aggaagctgg tattacagac cttccatcaa ctcttcacaa cgctttgaaa
     8761 gctttgacag aagatgaagt ggttaaagct gctctcggag atcacatcta cactagcttc
     8821 cttgaagcca aacgaatcga atgggcaagt tatgcaacct tcgtttcaca atgggaaatt
     8881 gataattatt tagaccttta ctaatataga agaaagattg cctgtgggta aacagtcaca
     8941 cagcagtcta agccatcaaa tacctataac ccttaaaata gcgatttcgg tcgctattta
     9001 tttttcgaaa aatcctcttg actcttttgc gaattagatt tatcatcaga cgtgtagaag
     9061 aaaatcaagg agtcactatg gaaaaattca atttcaaaaa caatatcggg caagaaaaca
     9121 agttacttca aatcgaaatc tacaagttta ctaacttttg caagcttcaa aattacacat
     9181 ctgtaaatat tttttcgaaa gatatatttg aagccatagt aaattgagac tagaatagta
     9241 cactacatct gctaaaaatt tctagaaatt aatttaactt tcctaatcga tttgtttaca
     9301 tcttatttca atctactata ttatctcaat aaatgatgat ggcgactgtt ttgtttgtgc
     9361 ttgtcgattt ttgaatcctg atcgagcgga agaatatttc tgccgaggtt gtcaagggga
     9421 aaatcctgaa gatattgaat tttatgatga acaattacag gcagaaaagg tggaggcttt
     9481 gaatattcga ttggaagtaa aaaattgaat tatctacaat ctcatcaaca ataaacctat
     9541 ttcaacccca ttatctatag gcgtattttt acgccttttt atatacttga agcacataag
     9601 aaacattatg ggaagtttgc tgatggaagc actcaagaaa ttgatgttcc ttatgatatt
     9661 cctgatactt gggagtgggt gaggataaaa tcaatttatt ggaattttgg gcaaaataag
     9721 ccagagaaat cctttaggta tatagatacg tctagtattg atagaaaaaa gaacataatc
     9781 aactacaaaa atctacaata tctttcacct gaacaagcgc cttcccgtgc tagaaaatta
     9841 gtttcgcaga atagtgtctt attttcaaca gttagaccat atctaaaaaa tattgctgta
     9901 gttagagaac ttaaagagta tttgatagct agtacagcat ttattgtttt ggatacttta
     9961 cttaacgaaa catatttgaa atattattta ttatcagata attttatcaa tcgtgttaat
    10021 aataaatcta ctggaacaag ttatcctgca atcaatgatt ataattttaa tctattatta
    10081 att
//
LOCUS       DAVLMQ010000060         9982 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000060 DAVLMQ010000000
VERSION     DAVLMQ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9982
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.060"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..235
                     /locus_tag="VXF95_001838"
     CDS             <1..235
                     /locus_tag="VXF95_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1082340.1"
                     /translation="KIYPQAQTPRKSSKLKPLTAEDKACNHALSKERSKVENIFAKVK
                     TFKMFSTTYRNHRKRFGLRMNLSAGIINHELGF"
     gene            284..748
                     /locus_tag="VXF95_001839"
     CDS             284..748
                     /locus_tag="VXF95_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HEV1082341.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            906..1331
                     /gene="lacA"
                     /locus_tag="VXF95_001840"
     CDS             906..1331
                     /gene="lacA"
                     /locus_tag="VXF95_001840"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HEV1082342.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMG"
     gene            1362..1877
                     /gene="lacB"
                     /locus_tag="VXF95_001841"
     CDS             1362..1877
                     /gene="lacB"
                     /locus_tag="VXF95_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HEV1082343.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1888..2817
                     /locus_tag="VXF95_001842"
     CDS             1888..2817
                     /locus_tag="VXF95_001842"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HEV1082344.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYYASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFAKHGDTFYKVDIPRIQVVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2819..3799
                     /gene="lacD"
                     /locus_tag="VXF95_001843"
     CDS             2819..3799
                     /gene="lacD"
                     /locus_tag="VXF95_001843"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HEV1082345.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4033..4869
                     /locus_tag="VXF95_001844"
     CDS             4033..4869
                     /locus_tag="VXF95_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1082346.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIIIGKGIAFGKRKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4905..5222
                     /locus_tag="VXF95_001845"
     CDS             4905..5222
                     /locus_tag="VXF95_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1082347.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5224..6918
                     /locus_tag="VXF95_001846"
     CDS             5224..6918
                     /locus_tag="VXF95_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HEV1082348.1"
                     /translation="MDKLIIFIEKGKPFFEKLSRNIYLRAIKDGFISSMPAVLFSSIF
                     ILIAAVPNIFGFKWSDEQLAFILKPYNYSMGILALLVAGTTAKSLTDSVNTRSMEKTN
                     QINYMSTFLAAVVGLLILAADPIEGGFANGLLGTRGLLTAFLAAFITVNIYKVCIKNN
                     VTIRLPEEVPPNIAQVFKDVIPFALSVLSIYGLDLIVRNIFGTNVAESVGKILAPLFS
                     ATDGYIGLAIVFGAYAFFWFVGIHGPSVVEPLIVAISYANIEANVQLVQAGMHADKIL
                     NPVTQTFVVTMGGTGATLVVPFMFMWLCKSKRNRIVGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFIPFVTAPIINVWIMKFFVDVLQMNSFSIILPWTTPAPIGIVMGTALAPLSF
                     VLAITLIIIDTLIYYPFVKVYDHQILEEERKGNSSSELKEKVAANFNTVKADAILEKA
                     GVDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAKYNVPVKAAAGGYGAHREMLP
                     EFDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7133..8539
                     /gene="lacG"
                     /locus_tag="VXF95_001847"
     CDS             7133..8539
                     /gene="lacG"
                     /locus_tag="VXF95_001847"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HEV1082349.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNAKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKEKGYKGEIGVVHAL
                     PTKYPLDPENPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTALEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGIGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIMRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8582..8758
                     /locus_tag="VXF95_001848"
     CDS             8582..8758
                     /locus_tag="VXF95_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000471575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HEV1082350.1"
                     /translation="MFKDFIQSIYEKVYIINFEKCSQIPCLTSEELKSLFLNFINPEE
                     WDTISFDSDFMPFQ"
     gene            complement(9042..9803)
                     /locus_tag="VXF95_001849"
     CDS             complement(9042..9803)
                     /locus_tag="VXF95_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1082351.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
BASE COUNT         3197 a         1720 c         2000 g         3065 t
ORIGIN      
        1 gaagatatat cctcaagcac aaactccacg taaatccagc aaactcaagc cgctaacagc
       61 tgaagataaa gcctgtaacc atgcgctatc caaggagaga agcaaggttg agaacatctt
      121 tgccaaagta aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt
      181 cggattacga atgaatttga gtgctggtat tatcaatcat gaactaggat tctagttttg
      241 caggaagtct aataaagaaa ctagcaaggt cagaccttac tttattggtg gacatccagg
      301 atttaattgt cttctacttg atgatgaagt ctatgaagat tattatctag agtttgagaa
      361 agaagagatt tgctctgttc cacgtccttt cccagaaaca ggtatgttgg atttccaaga
      421 tagaagtcca tggctagagg gacaaaaaga aatagatctt agttatgatc ttttcagcac
      481 agatgcagtg actttggatg aattgcaatc tcgaacaatt gcccttcgtt ctcttaaaca
      541 tgataaggga ttgaaagtgc attttgcaga atttccaaac ctcatcatct ggtcaacttt
      601 gaacaaggga cctttcatta cctttgaacc atggtctggc ttgtcaacat tccttgaaga
      661 aggagatcat ttagaagata agaagaatgt ttgtctctta gaagccaatc aggttgaaga
      721 attagggttt gagatagaag ttttataaaa aaagtaaaaa ataaataaca aaaacaaaca
      781 caaactgttg acttcttcaa acaatagtag tatattatgt ttgtgaggac taattgactg
      841 ttttttaaag acagccaata cactgctgga atccagcata gaaaaaataa aaaggagtat
      901 acaatatgtc tattgttatc ggcgcagatg ctgcaggttt gagattgaaa gaagttgtga
      961 aagacttctt agaaaaagaa aacttccacc ttgtggatgt tacagctgaa ggtcaagact
     1021 ttgttgatgt gactctcgct gttgctgcag aagtaaacaa agaagaacaa aaccttggta
     1081 tcgtgattga tgcttatgga gctggtccat ttatggttgc aactaagatc aaaggaatgg
     1141 ttgctgcaga agtatctgac gaacgttcag cttatatgac tcgtggccac aacaactcac
     1201 gtatgatcac tatgggtgca caacttgttg gtgatgaatt ggctaaaaac atcgctaaag
     1261 gatttgttaa cggtaaatac gatggtggac gtcatcaaat ccgggtcgac atgttgaaca
     1321 aaatgggcta attagattac agtaagaaag gtaagttaaa aatgagaatt gcaattggat
     1381 gcgaccacat cgtaacagat gaaaaaatgg cggtttcaga atttttgaaa tcaaaaggat
     1441 atgaagtcat tgactttggt acatatgacc atacacggac tcactaccca atctttggta
     1501 aaaaagtagg ggaagctgta actagcggcc aagctgatct tggggtatgt atctgtggta
     1561 ctggtgttgg tatcaacaac gctgtaaata aagttccagg tgttcgttct gccttggttc
     1621 gtgatatgac aacagccctt tatgctaaag aacaattgaa cgctaacgtt atcggctttg
     1681 gtggtaagat tactggtgaa ttgcttatgt gtgatatcat cgaagctttc attcatgctg
     1741 aatacaaacc atctgaagaa aacaagaaat tgattgcgaa aattgaacac cttgaaagtc
     1801 acaatgctca acaaacagac gcaaacttct ttacagaatt ccttgaaaaa tgggatcgcg
     1861 gagaatacca cgactaagag gtgacctatg attttaacag tcacaatgaa cccatccatt
     1921 gatatttcct atcccttgga tgagttgaag attgatactg tcaatcgtgt ggtggatgta
     1981 accaaaacgg ctggtggtaa gggactcaat gttacccgag tactttcaga atttggcgat
     2041 tctgttcttg ctactggttt agtgggtggc aaacttggtg agtttttggt tgaacatatc
     2101 gataatcaag taaagaaaga tttcttctca attcagggag aaactcgtaa ctgtatcgct
     2161 attctccacg gagacaacca aacagaagtt cttgaaaaag gtcctgaagt attggaacag
     2221 gaaggtcaag actttttgga acatttcaaa aaactcttgg agtcagttga agtagtggcc
     2281 atctcaggta gtctgccagc tggccttcca gttgattact atgcgagctt ggtagaactt
     2341 gctaatcaag ctggcaagcc tgtagtcttg gactgctcag gtgcagcact tcaggctgtt
     2401 cttgaatcac cccataaacc aacagtcatc aaaccaaata atgaagaatt gtctcagctt
     2461 cttggaagag aagtttctga ggatttggat gaattaaaag aagtacttca agaacctttg
     2521 tttgcaggga ttgaatggat tatcgtttca cttggtgcca acggtacttt tgccaaacat
     2581 ggtgacactt tctacaaggt agatattcct agaattcagg tggtaaatcc tgttggatct
     2641 ggagactcta ctgtggcagg aatttcttca ggacttcttc acaaagaatc ggatgcagaa
     2701 ttactcatca aggcaaatgt ccttggtatg ctcaatgctc aagaaaaaat gactggtcat
     2761 gtcaacatgg ccaactatca agctctatat gatcaattaa tagtaaaaga ggtataaaat
     2821 ggctttaaca gaacaaaaac gtgtacgctt agaaaaactt tctgatgaaa atggtatcat
     2881 ctcagctctt gcatttgacc aacgtggtgc tttgaaacgc ctcatggctc aacaccaaac
     2941 agaagaacca actgtggccc aaatggaaga acttaaagtc ttggtagcag atgaattgac
     3001 taaatacgct tcatctatgc ttcttgaccc tgagtatgga cttccagcaa ctaaagctct
     3061 tgatgaaaaa gctggtcttc tccttgctta tgaaaaaaca ggttatgaca caacaagcac
     3121 aaaacgcttg ccagactgct tggatgtttg gtctgcaaaa cgtattaaag aagaaggtgc
     3181 agatgcagtt aaattcttgc tttactatga tgtagatagc tcagacgaac tcaatcaaga
     3241 aaaacaagcc tacatcgaac gcatcggttc tgagtgtgtg gctgaagata tcccattctt
     3301 ccttgaaatc cttgcttacg atgaaaaaat tgcggatgca ggttctgtag aatacgcgaa
     3361 agtaaaacca cacaaagtta tcggcgctat gaaagtcttt tcagacccac gctttaacat
     3421 tgatgtcttg aaagttgaag ttcctgttaa cattaaatat gttgaaggct tcgctgaagg
     3481 tgaagtagtt tatacacgtg aagaagcagc agccttcttc aaagcgcaag atgaagcaac
     3541 gaacttgcca tacatctact tgagtgctgg tgtatcagct aaactcttcc aagatactct
     3601 tgtatttgct catgaatcag gtgcaaactt taacggagtt ctttgtggcc gtgctacatg
     3661 ggcagggtca gttgaagctt acatcaaaga tggtgaagca gcagctcgcg aatggcttcg
     3721 cacaactgga tttgaaaaca ttgatgagct caataaagtt cttcaaacaa cagcgacttc
     3781 atggaaagaa cgtgtgtaag aaagtcctcc tagtttagga acatgaatct aaaaaaattt
     3841 aaaaaaagtt gtatgtaaag gtttacaaaa caaccgactt gtgctatact taaatcacaa
     3901 gttaatacaa ggtgagtgtt actaagtaat attaggcatg atcacaggtg aattagaaat
     3961 cagctgattt tctagttcat ttgtggtcat tttttgtact catatacctt taagatataa
     4021 aaggaggttg acatgtatcg aattctaaat ccaatgaatc acaatgtctc gcttgttaga
     4081 aatgataagg gagaagaggt gattataatt ggtaagggga ttgcattcgg aaaaaggaag
     4141 ggggatttga ttgctgaaaa tcaggttgag aaaatctttc ggatgaagac cgaagagtcc
     4201 agagaaaact ttatggctct tctcaaagat gttccgcttg attttatcac agtgacctat
     4261 gaaatcattg ataagctatc aaagaaatat cattatccga ttcaagagta tctctatgta
     4321 accttgacag atcatattta ctgttcttat caagctctaa ctcaaggaag gtacaaggat
     4381 agtaatctgc cggatatttc cgctaagtat cctgtcgctt ttcaaatcgc aaatgaagct
     4441 tttgaaattt accgtcagaa gctagcagat cattttcctg aggacgagat tattcggatt
     4501 gcttatcatt tcatcaatgc cgaaggtgaa aatgaagtgg aacttgtgga gtcgattgat
     4561 aagaggaaag aaattctcag gaatgttgaa gaagttttaa cggactatgc aattcaacga
     4621 actaaaaaga ataaccattt ctatgatcgc tttatgatcc atttgaatta tttcttggat
     4681 tatttagaca gatctagaga tgataaccaa tcacttctgg atatggaaga tcatattaaa
     4741 caatcctatc caaaagcctt cgagattggt tccaagatct atgatgtgat tacgcaacat
     4801 acgggtcttg atttgtataa aagtgaacga gtttatctag ttctacatat ccaacgttta
     4861 ttgtcataaa aatttattta aaactatata aggagaattc tatcatgaat agagaagaag
     4921 taacattgtt aggttttgaa atcgtagcct atgctggcga tgctcgttca aaactattgg
     4981 aagccttgaa ggctgctgaa gctggtgatt ttgaaaaagc ggacgctctg gtagaggaag
     5041 ctggtagctg tattgcagag gctcaccacg cgcaaacaag tctattgact aaggaagctt
     5101 ctggtgagga cttagcgtat agtgtgacca tgatgcatgg tcaagatcac ttgatgacaa
     5161 ctatcttgtt aaaagaccta atgcaccatt taattgaact ttacaagaga ggagttaaat
     5221 aaaatggata agttaataat ttttattgag aaaggaaagc ctttctttga gaaattatcg
     5281 agaaatatat acttaagagc gataaaagat ggttttattt ccagtatgcc agcagtatta
     5341 ttctcaagta tttttatact aatagctgct gtgcccaata tttttgggtt taaatggtct
     5401 gatgaacagt tagcttttat tttgaaacct tacaactact caatgggaat tttagctctc
     5461 ttagtagctg ggacaactgc aaaatcgtta acagattcag ttaatacacg tagtatggag
     5521 aaaaccaacc aaatcaacta catgtcaact tttttagcag ctgttgttgg attgttaata
     5581 ctggcagctg atccaattga aggtggattt gctaatggtc ttttaggtac tagaggatta
     5641 cttactgcat ttttggcagc ttttattaca gtaaatatct ataaagtatg tattaaaaat
     5701 aatgtaacca ttagacttcc tgaagaggtt ccaccaaata ttgcacaagt ttttaaagat
     5761 gttattccgt ttgccttatc tgttctttca atatatggat tggatttaat tgttagaaat
     5821 atttttggta caaatgtagc agaatctgtt ggtaaaatat tagcccctct attttcagct
     5881 actgatggtt atatcggttt agctattgta tttggtgctt atgctttctt ttggtttgtt
     5941 ggaattcatg ggccatctgt tgtagaacct ttaattgtag ctatcagtta tgcaaatata
     6001 gaagctaatg ttcagcttgt gcaagctggt atgcacgcag ataaaatttt aaatccagtt
     6061 actcaaactt ttgttgtaac aatgggtggt actggtgcaa cactagtagt tccatttatg
     6121 tttatgtggt tatgtaaatc aaaaagaaat agaattgtcg gacgtgcgtc tgtagttcct
     6181 actttctttg gcgtaaatga accaatccta tttggtgctc caattgtttt aaatcctatc
     6241 ttctttattc cgtttgttac tgctcctatt atcaatgttt ggattatgaa attttttgta
     6301 gatgttctac aaatgaatag tttcagtatt attttacctt ggacaacacc tgctccaatt
     6361 ggtattgtta tgggaacggc gctggctcca ttgtcattcg tcttggctat aactttaatc
     6421 attatcgaca ctttaatcta ttatccattt gttaaagttt atgaccatca aattttagaa
     6481 gaagaacgga aaggaaactc ttcatctgaa ttgaaagaaa aagttgctgc aaacttcaac
     6541 actgtaaaag cggatgctat tcttgaaaaa gcaggtgtcg atgcagcaca aaataccatc
     6601 actgaagaaa caaatgtcct cgttctctgt gctggtggag gtacaagtgg actccttgca
     6661 aatgctttga ataaggcagc agcaaaatac aatgtccctg tgaaagcagc agcaggtggc
     6721 tatggtgctc accgtgaaat gttgccagag tttgatcttg ttatccttgc ccctcaagtt
     6781 gcttcaaact ttgaagatat gaaggcagaa acagataagc tcggtattaa acttgctaag
     6841 acagaaggcg ctcaatacat caaattaact cgtgatggaa aaggtgccct agcattcgta
     6901 caagagcaat tcgattaagg ctaggaactg tgaaacagtc tcccatcgtt acggaaatcg
     6961 ctatggcgaa tttcctaatc gccttattaa ttcgtcggta aaaagatatc gtttttacct
     7021 cctcatgtca caattcagtg atttggcaca agaagtgaga tggagaagca tggctcactg
     7081 actcctctcc tctcactttt actttattta aatcaagaaa taggtgaaaa aaatgacaaa
     7141 aacacttcca aaagacttta ttttcggtgg cgcaacagct gcttatcaag cagaaggtgc
     7201 tacacatact gatggaaaag gaccagttgc ttgggataaa tatcttgagg ataactactg
     7261 gtacactgcc gaaccagcta gtgattttta caatcgatat ccagttgacc tcaagctagc
     7321 agaagagtat ggtgtcaatg gtattcgaat ttctattgct tggtcacgta ttttcccgac
     7381 tggttacggc caagtaaatg ctaaaggtgt tgagttttat cataatttat ttgcagagtg
     7441 tcacaaacgt catgttgagc cctttgtaac tcttcatcac tttgacactc cagaagctct
     7501 ccactcaaat ggagacttct taaaccgtga aaatatcgaa cattttgtag actacgctgc
     7561 cttctgtttt gaagaatttc cagaagtaaa ctattggaca acctttaatg aaattggacc
     7621 aatcggtgat ggtcaatatt tggttgggaa attccctcca ggtatccagt acgaccttgc
     7681 caaagtcttt caatcacacc acaatatgat ggtgtctcat gcacgcgcgg taaaattgta
     7741 caaagagaaa ggctataaag gggaaattgg tgttgttcac gccctgccta ctaaatatcc
     7801 tctagatcct gaaaatccag cagatgttcg tgcagctgag ttggaagata tcatccacaa
     7861 taaattcatc ttagacgcaa cttatctagg tcgctattca gctgaaacca tggaaggtgt
     7921 caaccatatc ttatcagtca atggtggtag tttggatctt cgtgaagaag attttacagc
     7981 attagaagct gcaaaagact tgaatgattt cctaggaatc aactactata tgagtgactg
     8041 gatggaagcc tttgatggag aaactgaaat tatccataat ggtaaaggtg aaaaaggaag
     8101 ctctaaatac caaatcaaag gtattggtcg tcgtgtagct cctgactatg taccacgcac
     8161 ggattgggat tggattatct accctcaagg tttgtatgac caaatcatgc gtgtgaagaa
     8221 agattatcct aactacaaga agatttacat cactgaaaat ggtctcggct ataaagatga
     8281 gttcgttgat aacactgttt acgatgatgg tcgtattgat tacgtgaaac aacacttgga
     8341 gatcttgtct gatgcgattg cagatggagc taatgtaaaa ggttacttca tttggtcatt
     8401 aatggatgtc ttctcatggt caaacggtta tgagaaacgt tatggtctct tctacgtaga
     8461 ttttgaaact caagaacgtt atcctaagaa atcagctcac tggtacaaga aagtagcgga
     8521 aactcagatt atagactagt agaattagtc attagatata gaattttagt gagtcaaaaa
     8581 gatgttcaaa gattttatcc aatctattta tgaaaaagtt tatattataa atttcgaaaa
     8641 atgctctcaa ataccgtgtt tgacgagtga agaattgaaa agtctatttt taaattttat
     8701 caatcctgaa gaatgggata ctatctcctt tgattcagat tttatgccgt ttcaataatc
     8761 gtaaccaatt tctcaaaaaa gttaaatctt atatttagta ctctgcaaaa ctcttatcta
     8821 atcacgttgc ttatactcaa tgaaaatcaa agagcaactt taaactagga agcgagtcgc
     8881 agatttctca atgcatagct ttgaggaatt gggcaaaaag tctttgatat agaaaaagca
     8941 tagtatcagg tgtttcaaca cctgatacta tgctttttat tgtgggaaga tttacttttt
     9001 ttcttctgaa attgagttgt tacccaggct ctttcagttt attaaggctt gatgacttta
     9061 atgtgtttag atagcttaaa aaggattgaa tcacttagtt tagaatctga aacaatagta
     9121 tcaagatttg atacattata aaaagtataa aaatcaaact tattgaactt actatgatct
     9181 gcgagtaaat attttttatt agaattattt aaagcgatgc gttgagcctc tccctcttcc
     9241 tcgctaaaag tagctagagc tccgttttga ataccattac agctaacgaa agctttagaa
     9301 aattggagat tagagagatt ttgtagggtc aatgtgccaa caaaagcacc tgtaatatcg
     9361 cgataatttc cacctatcaa aatcaaatct gttaattttc gttcgcttaa aatcagaaaa
     9421 acaggtagac tgttggttac gacgcggata ttgtcaatag gcaactcacg cgcaaaaaac
     9481 tctaatgttg ttcctggtcc aatgaaaata gtttctcttt cttctactag actgcctgca
     9541 aaatgggcta tttcttgttt ttctgccgtt tggagggctt gtttttcaat atttgatcgc
     9601 tcattagtca aaagggagtt ggttcgaagt ttttcagctc caccatgcac acgaatcagc
     9661 aaatctttat cagctaattc ctgtaaatag cgccttgcag tcatatctga aacggctatt
     9721 tcgtccataa tctgtttaac tgttatggtt cctttactat ttactatctc taaaattttg
     9781 gttaattttt cttgtttgag catattatca cctcgtttcc tactactatc ttaccataaa
     9841 ctagctcatc attcaaatac aaaaacaaca aaataaaaca aaaacaaaaa tatcgaagtt
     9901 tattttcaaa actttcgata tttttattaa gttattattt tgttgtttct agtttacttt
     9961 ttgatggtta agagtggtgg ag
//
LOCUS       DAVLMQ010000061         9969 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000061 DAVLMQ010000000
VERSION     DAVLMQ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9969
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.061"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..485)
                     /locus_tag="VXF95_001850"
     CDS             complement(<1..485)
                     /locus_tag="VXF95_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082352.1"
                     /translation="MNRLVNDSRKCEILLFKISIIVVSVIVLVMSIVGAYYFKNCLWD
                     KESLNLILTLDTLFAVFITFFSFSNDKSSNIFGISPNEIIRTQSEVYQFLFTKSFATL
                     LIVTNLLSIIHYFGAKNLIVSFNETYPRIQSSVGIMWLPLFGILIIYFIWLLIEGLKY
                     I"
     gene            complement(624..3125)
                     /locus_tag="VXF95_001851"
     CDS             complement(624..3125)
                     /locus_tag="VXF95_001851"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HEV1082353.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSSEQ
                     AEAVADYKHQASLKSDLVRTDLAKEKTGVWTGAYAINPVNGKEMPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVAYLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPETELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVTTDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEILAENNGALD
                     KAYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYIDYAKGFIQLIAPFAPHL
                     AEELWQTVAETGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKAEIDGKEIVKVIAVPNKLVNIVVK"
     gene            complement(3580..4668)
                     /locus_tag="VXF95_001852"
     CDS             complement(3580..4668)
                     /locus_tag="VXF95_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HEV1082354.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNCPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
     gene            complement(4686..5354)
                     /locus_tag="VXF95_001853"
     CDS             complement(4686..5354)
                     /locus_tag="VXF95_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HEV1082355.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEAGADYLAPYYNRMENLNIDSNSVIRQLVLAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVIQN
                     SRSI"
     gene            complement(5373..7811)
                     /locus_tag="VXF95_001854"
     CDS             complement(5373..7811)
                     /locus_tag="VXF95_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HEV1082356.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQYILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            complement(7962..9260)
                     /locus_tag="VXF95_001855"
     CDS             complement(7962..9260)
                     /locus_tag="VXF95_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1082357.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASGNLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            complement(9277..9585)
                     /locus_tag="VXF95_001856"
     CDS             complement(9277..9585)
                     /locus_tag="VXF95_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1082358.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQSSGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            complement(9631..9951)
                     /locus_tag="VXF95_001857"
     CDS             complement(9631..9951)
                     /locus_tag="VXF95_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1082359.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
BASE COUNT         3119 a         2099 c         1616 g         3135 t
ORIGIN      
        1 ctgatatatt ttaatccctc tattaagagc caaataaaat agattatcag aataccaaac
       61 agtggtagcc acatgatacc aacactggat tgaatacgag gataagtttc attaaaagaa
      121 actattaaat ttttggctcc aaaataatga ataatggata acaaatttgt cactattaat
      181 agagttgcaa aagattttgt aaataaaaat tgatacactt cagactgtgt ccttataatt
      241 tcatttggag atattccaaa aatattgctt gatttatcat ttgaaaaact aaagaaagta
      301 ataaaaactg caaagagagt gtctaaagtg agtatcaaat ttaaactttc cttgtcccaa
      361 agacaatttt taaaataata tgcacccact attgacatta ctaatactat aactgacact
      421 acaataatag aaatcttaaa taataaaatt tcacacttcc tgctatcgtt cactaatcta
      481 ttcattctga cctattctaa aagtaactct aaagttcata ctctagagtt acttcttttt
      541 atttcacaac aatgttaact aatttagttg gcttcaatag tccagtggac tattgaaggt
      601 ggcagataga gctaataaac tcgttattta acgacgatat taacgagttt attcggtacc
      661 gcaattactt tcacgatttc cttaccgtca atttctgctt tgactttttc atcagctaaa
      721 gcgatttctt gtaattcttc acgtgataga tctttagcaa ccatgagttt ggcacgaact
      781 tttcctttga tttggacgac aatttcaatt tcatcttcaa ccaatttgct ttcgtcccaa
      841 gttggccaag ctacataaga gattgactca cctgtttctg cgactgtttg ccagagttct
      901 tctgccaagt gaggtgcaaa tggtgcaatc aattgaataa agcctttggc atagtcaata
      961 taaagcttat cttccttgtt agcagcattg acaaagacca taagttgggc aatagctgtg
     1021 ttgaatttga gagactcaat ttgctcagta acagctttga ctgtttcgtt gtaagccttg
     1081 tcaagagcac cattgttttc cgcaaggatt tctttacttg taatcaaacg gtaaactcgg
     1141 tcaaggaact tacggcttcc ttccaaacct tcttctgacc aagcaatcga agcatcgagt
     1201 ggtcccataa acatttcata aacacgaagg gtatcggcac cgtattgttc caccacatcg
     1261 tctgggttaa caacgttctt gagcgattta gacatcttgg ctggcgcttg ctccaactct
     1321 tcccctgttt ctacatggaa gaaggaacca tcacgttttt caaccttgtc ggttgtcaca
     1381 agagcaccac ggtggtcacg gtagcttgtt cccaaaatca tcccttggtt aaagagtttt
     1441 tggaatggtt ccttagtcgg aacaacaccg aggtcataga ggaatttatg ccagaaacga
     1501 gcataaagca agtgaagtac agcatgttcc gcaccaccca cgtagatatc tactggcaac
     1561 cattgtttga ggaggtcctc atcagccaat ttctcagtat tgtgcgggtc aatatagcga
     1621 aggtagtacc agcttgaacc agcccattgt ggcatggtgt tagtttcacg acgacctttg
     1681 acaccatctt cacgagtcac ttcaagccag tctgtcaagt tagctagtgg actttcaccg
     1741 gtacctgaag gacggatgtc cttggtgaca ggcaagacaa gcggcaattc agtttcagga
     1801 acagctgttg aagttccatc ttcccaatga ataattggaa ttggttcacc ccagtaacgt
     1861 tgacggctaa agagccagtc gcggagacgg taggtaacct tctcctgacc acagcctttt
     1921 tcttccaagt aagccacaat cttggcaata gcgtcttctt tgttcaatcc atctaggaag
     1981 tctgaattga catgcaggcc atcctctgtg taggcagctt cttcgacatt tccaccttca
     2041 agtacttcga cgattggaag gtcaaattgt ttggcaaatt cccagtcacg ttggtcgtgg
     2101 gcaggcacag ccataaccgc acctgttcca taactagcaa gaacatagtc cgcaatccag
     2161 attggcattt ccttaccatt gacagggttg atggcataag caccagtcca aacaccagtt
     2221 ttttccttag caaggtctgt acgaaccaag tcagacttaa ggctggcttg gtgtttatag
     2281 tctgctacag cttctgcttg ctctgaactt gtgatagcgt ctactaattc atgttcagga
     2341 gccaagacag tgaaagtcgc accgaaaagt gtgtccggac gagtagtaaa gactgtaaat
     2401 tccttgtctg ttccttttac tttgaaagtt acattggcac cagttgattt accaatccag
     2461 ttgcgttgca tatccttgat agactctgac caatctagtt catctaagtc attgagcaag
     2521 cgctctgcgt aagccgtgat tttgagcatc cattggcgca ttggtttgcg gacaactgga
     2581 tagcctccac gctcagaagt tccgtcagga agcacttctt cattggcaat ggcagttccc
     2641 aattcctcaa cccagtttac tggcacttca gcttcatagg ccaagccttt ttcgtaaagc
     2701 ttggtgaaaa tccattgagt ccacttgtag tagtttggat ctgttgtgtt gacttcacga
     2761 tcccagtcat aagaaaatcc aagcgcattg atctgacgtt tgaagttggc aatgttttcc
     2821 gctgtaaatt ctgctgggtc attaccagta tccatagcgt attgctctgc aggcaaacca
     2881 aaagcatccc aacccattgg gtgaaggaca ttgtagcctt gcgcacgttt gtaacgactg
     2941 aggatatcgg ttgcagtata accttctggg tgtcctacgt gcagaccagc tccagacgga
     3001 taagggaaca tatcaagcgc ataaaactta ggttttgatg catctgttcc tgtcttaaat
     3061 gtatgatgtt ctgcccagta gccctgccac ttaggctcaa tttctttatg attataaaaa
     3121 ctcatggtct ctctccaatt ttgtgatgtt actattatac catttttgag ggaatttgaa
     3181 atgtgtttaa agaaaaaact gtatactgta tctcattaat tttgatgact atgaattgct
     3241 ctatctccca ctttttatcc cattgttatg cagtaaatca aggagtaagt caagaagctt
     3301 atctcgtata gcacaaaata cttattttag accgaagata aaactggaat gctaattaat
     3361 gtattcacaa taaatagccg actacctatg tcgctttttg atttatgaag aacgtatagt
     3421 agactgaatc tgaaatagta cgaaacaatt gctaaaacat ttatagaaat taattttact
     3481 ttcccaatcg atttgttctc atcctatttc aatcttctat agaattcaat acagggatca
     3541 ataaaagact accatttgga aaacagtagt ccttattgtt tattttgaat ttacataggc
     3601 atctacagcg ataatagctt gagcaacatc tgaaggcgaa atcttaaacg gcatctgatg
     3661 aattgtctca ccctccatag ttgcttgttt accaactttt attaaatcat catatccaac
     3721 ttgatccaaa tgcatttctt ttagagttgt tggcatacca atttttttgt aaaactcaat
     3781 atacttatca agttcttctt taggtctatt ttccaataat agttgtacta aagttccata
     3841 agctactttt tcaccatgtg ttaaatgatg aatgtcacct gtcaatgcag taaaaccatt
     3901 atgaattgca tgcgccgcag ctaatcctcc actttcaaaa cctagaccac tcaataaagt
     3961 attagcttca acaatatttt ctaatgctgg tgtcaccact ttagcttcac aagctgccat
     4021 agcctgtaaa ccatctgcaa acagcgtttc ttcacatttc ttcgcaattg caactccagc
     4081 caatgtttgc tgttgtccca acatagtttt tccatttgcc tgcataaccg cacgcgcctc
     4141 aacccaagtt gctaaaccat ctgcaatacc agacgctaat aaacgcttag gggcttgtga
     4201 aataactttt gtatcaacca aaactaaatc tggattttta gaataaaata gataatgatc
     4261 aaatgcacct tcatctgtat aaataacaga taaagcagat acaggtgcgt cggtcgatgc
     4321 aattgttgga gcaataataa caggcttttc aatcaaatct gcaatagctt ttgcgctatc
     4381 aatcgtcttt cccccaccaa gaccgataat actatcacaa ttttctttct cagccaaggc
     4441 aacaactcga ttgatttcat tgtcagaagc ttcaccatta aatagcgcca gaacaatatg
     4501 gaaaccatac ctatgtaggt aatcttcaaa tcgttttcca acaatatcat aaaccaactg
     4561 atcgcataat agaatagggc aatttcccaa atccaaaatt gatttggcat tttcaaacaa
     4621 ggcattttcc ccctgaatat atctagaagg actagcaaaa attctcatat gtatttcctc
     4681 tctatctaaa tggaacgact attttgaata acaaaccaat cgtcagaaaa atcatcaacc
     4741 gccttttgga tagatggcat ggcgaaagct gattcaaaaa catccgctcc tgctgtaaca
     4801 gcatgcgcac ctgcagctaa agcattattt acttgtgcta catttttaaa ggatgcagcc
     4861 aaaatcttac taggagagtt ctgtctatca atagcaagaa ctaattgacg aatgacagaa
     4921 tttgaatcaa tgttcagatt ttccattcta ttataatatg gagctaggta atccgctcct
     4981 gcttcgatag ctaataatcc ctgaataact gtataaatag ctgttgcagt gatatggtag
     5041 ccctcttttt ttagcacctt tattgcacgt aatccagctg gagtaacagg tactttgata
     5101 aatatatcat ctcctgcttg tcttcgaatt tcatgagcat cctttaagat gccttcaaaa
     5161 tcttgagaaa tcacctgaac atgaatagag ggtgtagagc caatcaattc tcttacatct
     5221 ttgattcgtt caaaaaaatt aatagaaccc tctctttttg caatagtggg atttgaagtt
     5281 accccagcta gcggcaaaat ttcagaccac tttttaatct catctaaatt taatgtgtca
     5341 agcataaatt ccataaaaag aacctcttta ttttacaaag tatgctcagt acgtcctata
     5401 atgtcatctt gggttgcctt agaaagaaca ttgaagaatg cagagtatcc tgcaacacga
     5461 acaattaagt ctctgtgttt ttcaggatgt ttctgagcgt caatcaacgt ctctctggaa
     5521 acaacattgt attgaatatg gtacccatgt aaacgattaa agaatgttcg taacaaagca
     5581 attagtttta atttatcttc ttctttggct aacgtttgag gatttacttt ctgatttaag
     5641 agaaccccac ctacgatttc atctgttggt aattttgaaa cagattttaa aacagatgta
     5701 gggccgtgtt gatccatatt atgtgatggt gaacaaccct ctgctaacgg tgtacccgcg
     5761 ttgcgtccat ctggagttgc taatgttcca cgtccctgcc ctacgttggc tgagatagaa
     5821 gatgttcctg aataacgaat tcctccaatt ggacctcttc cataacgtgt attaggatat
     5881 ttagcaattt catcaacata aatgtcataa gcagcagtaa ccaatttgtc agcataatca
     5941 tcatcattac catacttagg tgcatcatga atcaacattt cttgaatgac cttaccttct
     6001 tctccggcat aatctgtttc cagtgcatgc caaagctgac ttgggcttat acgttcttcc
     6061 tcaaacacca attttttaat tgcagctaat gaatccgaca aatttgcaat tccaacttgc
     6121 aatcctgata tataatcata tactgctcca ccttctttaa ggtgttttcc acgaccaata
     6181 caatcatcag tcaatgctga acatagaata tcaggaactt ctcgttccaa tgataaatca
     6241 atagaatttt caacaataac actcattcgt gtcaaatatc ttagtgtttt atcccaagca
     6301 ttttctaatt cagaaaagtt cttcatatcc ttaaaatgac caaagcttgg tgcaaaccgt
     6361 ttacccgaag ccggatcaat tccatcattc atcgtgataa gtagaacctt agggaagttc
     6421 atataactca tacctgtgca acgatagccc catttccctg gaactgccgt ttcaacacat
     6481 ccaatggcac tgtaatcata agcatcatct tccaatactc cttttgcaat aaaagaagga
     6541 ataataatct catcattatt aaatgcaggc ataccaaaac caagtttcat cacttcaata
     6601 cactcattca tgaaacgagc atctaaacct gcatggtaac gtacagttag attaggttgc
     6661 ggtagatggg tttgtgcaac tgattttaat accaaataag ataatgggtt aacagcatcc
     6721 ttcttatctc gagtctgtcc accaattgta acattttgat ataaaggact tcctgctgaa
     6781 gaaaatgtat gtgattgact gcgaacctta ttaattgtaa ttgtcttaat ccaaagattt
     6841 gtcagacgtt caacaatgct atcttctgtt tctttaccac tttctaaatc agccttcata
     6901 tatggataca tatattgatc aaaacggcca tatgaaagag agtggccatt agattcaatt
     6961 tgtaaaatat attgaataaa ccaaactgat tgaatagctt ctgcaaaagt agttgccggt
     7021 tcatatggga ctctagagca aatatctgca atctcaagta attctttctt acgtttagga
     7081 tttgcatttt cggctaaact tttagcaaga gcaacaaagc gctttgcata tactttaata
     7141 gcatcgatta cgataaatat agagtcgtaa aaatgatatt tatcaatact tgctggatct
     7201 gttaaatcta gagctacttt tgctttacga gcccgctctt caaaacctct taaaccaaat
     7261 tgcaaaagtt tctgatagtt aactgctaag tgagcatctc cagaattcat cttaccttcc
     7321 ataccgaaga atcctgtttc catataaact gacacttctt caggtaataa ggcaccagct
     7381 ctagcacgta aattattatt ttcccaaaac ggagcaatac ttctaagttg ttcttttgtt
     7441 tcttctgtaa tatagaaaac atctccatca cgcttttcaa aaagatccaa ctcattgaga
     7501 acaaattcta gcgtatattc cggaaaaata ggagcatctt tattggaaga agcttgattt
     7561 cccgcaatca tagattcttc ttcaatatag atagacatat tttccaaaat ttctttcagc
     7621 atatatgcac gttttaggac attaggttgt tccttgtatc gttcataggc gcgtgttgct
     7681 agaactgctc tctcagcatc aatataaggt tttttattta aaacatcttc tcgatatttg
     7741 ttcatccttt cagtaaggct gccaaaatat tctgttttga ttgttgttct tgctacttct
     7801 gtatttacca tcgtaagcac ctttctttcg aaaatatttt tatttctttc gaaaatataa
     7861 taccgatttt tatagaaatt ttcaagcttt taactagaaa aattttaact ctctaatttt
     7921 tagcacaaat gtgtgagttt aacagtaaca cacaaatacc tctaagattg tttgatttca
     7981 ttttggtaag ctaaacgatc ttgtatctta aagaatggaa agtaaaccac tgtagatatc
     8041 accaatacta ataactgagt cacaacacct tgccatccac ccaccaaaaa tcctgataga
     8101 atagctggtg tactccaagg caatgttacc cctgagaatg gctgcatgaa acctgttgca
     8161 atagctccat atactatcac agctgcaagt acaggaacaa gaatgaaagg tacaaacata
     8221 actggattca tgacaatcgg aaatccaaat acaactggct catttacgtt aaatattgct
     8281 ggaaaagctg caacttttcc taaggcttgg tattgttttg attttgctgc aaaaagcatg
     8341 gcaactacaa gaccaaacgt aatccctgaa cctgatagaa ttaaaaatga atctaaaaat
     8401 tgttgagtaa caatatgtgc accattttct aatgatagat taccagaggc taacatagct
     8461 ttattagcat caagattaga taaaagcaga gctgtcacta ctccatttac taccgattgc
     8521 ccatgaacac caaaccacca caaaaatgat ataaagaatg caattccaat agcaccatac
     8581 aaagatccag ttaaaccttg caacggaact tgaatagcag aataaatcat ttctatgaat
     8641 gttccgccat tagtcaatga cttcgctaaa atatatacaa tcatagaaga taagaaaatt
     8701 acaaatgctg gaatcattgc ttcaaactgt ttggcaatag cttgtggaac ttgttctggc
     8761 atcttaataa caatttttct ctttataaag aaggtataaa tacttcctac taccaaacct
     8821 ataatgatag caccgataat tccttggcct ccaaaccaaa ctttactaat agcgtcccca
     8881 atcgcctcac cttgtttagg gatataagat gatcttagca aaataaagaa tgcagataca
     8941 gatagaactc cagctggtaa agcctctact ccgctattct tagcataaga ataggcaatt
     9001 gaaaaacaag aaattagacc cataatagca aaagttcctg aatatacttg cataaacggc
     9061 tctgtccaat tagctccaaa aacactagca atgctcttat ttaatccttc gaacggcaat
     9121 tgtcccataa tcaagaacaa actgccaact actgtcaatg gcaaaattgc taacatccca
     9181 tcttttagag ctataatgcc acgcatattc acaaacttca tcatcggtgc aatgattttc
     9241 tgaacatcca tctttgacat aataaatctc cttttcttac ccactaatca aagatagggc
     9301 caaatctaat acttttttcc catctaacat accatagtcc atcatcggaa taacagctat
     9361 cggaacatca cacttatcac aaatttcttt tgatttatct aatgtataag caacttgtgg
     9421 acccaatagt gcaacatcta tatttggcgc ataatccgct aatttagact gagaaaacgc
     9481 ctctatttct gcctcaactc cactagattg cgctgcaatt ttcatattat ttacaagcat
     9541 accagtagaa aaacctgctg cacaaaacaa accaatcttc accattatgt tttcctcctc
     9601 tatgttaata acaatgataa tactctagta ttatttttta tgaagttctt ttctcaaact
     9661 aataatttct ttgattaaat taatctccgt catactagtc atgagatgat cttgtgaatg
     9721 aacaaagaga gctgtaattt ctgtctttgt accagacgct tcctgtgcca agaattttgt
     9781 ttgtagatta tgagcttcta ataaggctgc atcagctaac tggatttctt cttcacaccg
     9841 ttcacatgta ccatttttta tgtaatctaa cgctttataa atatgttgtt tcgcatcacc
     9901 agcatataaa attaaaccca tgataatttg atctggaaca ataatttcca taaattcctc
     9961 ctcatttca
//
LOCUS       DAVLMQ010000062         9672 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000062 DAVLMQ010000000
VERSION     DAVLMQ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9672)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9672)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9672
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.062"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(160..2142)
                     /locus_tag="VXF95_001858"
     CDS             complement(160..2142)
                     /locus_tag="VXF95_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HEV1082360.1"
                     /translation="MKSSRLLALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNIFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVTFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGASEPILYKYLELQ
                     DKAITVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2388..3242
                     /gene="rfbD"
                     /locus_tag="VXF95_001859"
     CDS             2388..3242
                     /gene="rfbD"
                     /locus_tag="VXF95_001859"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HEV1082361.1"
                     /translation="MILITGANGQLGTELRYLLDERNVDYVAVDVTEMDITNSEMVEK
                     VFAEVKPTLVYHCAAYTAVDAAEDEGKELDFAINVTGTENVAKASEKYGAILVYISTD
                     YVFDGKKPVGQEWEVDDIPDPQTEYGRTKRMGEELVENLTSQHYIIRTAWVFGNYGKN
                     FVFTMQSLAKTHKTLTVVNDQYGRPTWTRTLAEFMTYVTENQKEYGYYHLSNDAAEDT
                     TWYDFASEILKDSDVEVVPVDSSKFPAKAKRPLNSTMSLAKAKATGFVIPTWQDALKE
                     FYKQEVRK"
     gene            complement(3304..4350)
                     /gene="rfbB"
                     /locus_tag="VXF95_001860"
     CDS             complement(3304..4350)
                     /gene="rfbB"
                     /locus_tag="VXF95_001860"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HEV1082362.1"
                     /translation="MTEYKKIIVTGGAGFIGSNFVHYVYNNFPDVHVTVLDKLTYAGN
                     RANIEEILGDRVELVVGDIADAALVDKLAAEADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGTYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGLGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQPAD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKETIKWYTDNQDWWKSEKE
                     AVEANYAKTQQVIK"
     gene            complement(4362..4955)
                     /locus_tag="VXF95_001861"
     CDS             complement(4362..4955)
                     /locus_tag="VXF95_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HEV1082363.1"
                     /translation="MSDNFFGKTLAVRKVDAIPGLLEFDIPVHGDNRGWFKENFQKEK
                     MLPLGFPESFFVAGKLQNNVSFSRKNVLRGLHAEPWDKYISVADDGKVLGSWVDLREG
                     ETFGNVYQTEIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLAEAEVSEADKHHPLLRDVKPLTKDEL"
     gene            complement(4956..5825)
                     /gene="rfbA"
                     /locus_tag="VXF95_001862"
     CDS             complement(4956..5825)
                     /gene="rfbA"
                     /locus_tag="VXF95_001862"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HEV1082364.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIKDILIISTPQDLPRFKDLLLDGSEFGIKLSYAEQPSPDGLAQAFLIGEEFIGDDSV
                     ALILGDNIYHGPGLSKMLQKAAQKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEK
                     PENPRSNYAVTGLYFYDNDVVEIAKGIKPSARGELEITDINKVYLNRGDLSVELMGRG
                     FAWLDTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLELAQPLKKN
                     EYGQYLLRLIGEA"
     gene            complement(5966..6793)
                     /locus_tag="VXF95_001863"
     CDS             complement(5966..6793)
                     /locus_tag="VXF95_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIA family hydrolase"
                     /protein_id="HEV1082365.1"
                     /translation="MINKVDYFGMDISDLKNKKLFLFDMDGTIYEEDRLFDGTLQLLE
                     YIQSIGGEYIFITNNSSKSVVDYIEKVNQLGIVAKRENFFTSAQATIVFIEEKYPHAK
                     VYCQGTKSLLKELSDSGIDVTDQVRDNIDLVLVGFDTELTSEKIRNTCEVLSTRDVPF
                     IATNPDVRCPVSFGFLPDCGSICEMISKSVDKTPIYIGKPEPTMVNIVRKKLNYSLSE
                     TVVIGDRLYTDIMTGINAGVSSVCVLTGEATADDIQQGSIKPTYTFRTVKEMWEGII"
     gene            complement(6814..7518)
                     /locus_tag="VXF95_001864"
     CDS             complement(6814..7518)
                     /locus_tag="VXF95_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="HEV1082366.1"
                     /translation="MKALILAAGLGTRLAPITNDVPKSLVPVNGKPILIKQIENLYQN
                     DVTDITIISGYKASVLKDVISGKYPEIKIIDNVDYKITNNMYSAYLGKDAMGSSEFLM
                     MNADVFYDASVIKSLLLHEAPNAIVTDLGTYIDESMKVVEKNGRLVEISKQISPEEAL
                     GASIDVYKFSPDAGACFFEKCREFIEDKNELQLWSEVALNAILQAVEFVACPLDGRWL
                     EIDNHEDLAAAEKLFA"
     gene            complement(7534..8562)
                     /locus_tag="VXF95_001865"
     CDS             complement(7534..8562)
                     /locus_tag="VXF95_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000794266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HEV1082367.1"
                     /translation="MKNNVLKIGSGAIHQISSTLAQNNISGKILYCADPIVDNLYGSL
                     VRSQIEEIGRLKEESCNYNTIAYAMNIAERVIATDIDCIVGMGGGRVLDVCKYASYIS
                     KRPYLSIPTTAANDGIASPVAVLKRQDDRPKSLGAAIPSMTLIDIDVIASGPIQNIKA
                     GIGDTISNYTALKDWELAVNRGKDEMHGFAYLMSQNSLDALMKTKYNSITPDFIEVLI
                     NSLVLSGIAMDFAGSSRPVSGSEHLFSHALDYYGSKRNLHGIQVALGTVAVLKIIEDP
                     ITPVTDYLQRFEVNINPKQMGIDEDLFVYCMQHATTMRNNRYTYLHEADLSTARVKQI
                     YKELVNEL"
     gene            complement(8598..>9672)
                     /locus_tag="VXF95_001866"
     CDS             complement(8598..>9672)
                     /locus_tag="VXF95_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000636508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CDP-glycerol glycerophosphotransferase family
                     protein"
                     /protein_id="HEV1082368.1"
                     /translation="VRLKNNKILFINFNGKGYGDNPKSICEYLRTTYPELDLVWLTKE
                     TKGFPDGVRLVKYGSIRAFYEQASSKVWVYNVRAFARILKRKEQFYIQTWHGASSFKL
                     IEKQAELPLNYVLEAKYDARVTDLMISDSKKQTEEYRKYFWYTGEILEVGMPRNDSLF
                     HCKDDYNKLENVRKELNISCDDFVILYAPTFRDNGDISYLNLDFLRLLQSVEKGIRKN
                     CKLLIRLHPNHSQFCRNILFNQDIINVTFFSDMQELILLADVLLTDYSSSIFDFILLN
                     KPYVRYVNDLEEYSKLRGLSDTYYELPDTIISTSEELYTLLPEKINDFDYAAINQYRN
                     GTLSPMFNGRASENIGRRIIQEL"
BASE COUNT         2910 a         2058 c         1631 g         3073 t
ORIGIN      
        1 gcaataggaa acaagtaaaa ttaacaaaaa ttttctctat tctgacaaaa agaggctcca
       61 acttttgggg gtcagtacat ttagaatctt tctttacaaa tataaaaagg attcagcatt
      121 caagagaaat actaaatcct ttcttatatt ttgcaacagt tatttcacat gttttgcgag
      181 atcttcttga gcctttttat tagactcttc tttttctttc atccattttt cctgagcttt
      241 ttggtattca tctacagtga ttgccttgtc ttgaagttcc aagtatttat acaagattgg
      301 ttcacttgca cctttatttc ctgacaatgc aaatggtatt gtaaatggta ccatcttaga
      361 caagattggg cgccctgtac gagatgtagt tggaataatc aaagcactat ctgtcaacca
      421 agcttgggct gcagcgtatt tatcatagcg tttagcaaca tctgtagcct catcaccagc
      481 ctcagtgacc aatttttcgt agtcatatag acctactttt ttagcagcta cattatcttc
      541 ccctgagtca aaccctaaat atgttttagt actttctcct acagatggtt tgatgatatc
      601 aaggtaggtt gatggatcgg caaagtctgg accccaaccg acattatctg ataaatccca
      661 gtcttcgcca gcagcatttt cagcaaaata tgtaatattg tttacttcgt ctttttgtag
      721 ttgttggata tcaataatga cattatcagc tcctaaagtt gcttccaagg attgtttcat
      781 agattggacg cgctgaactt ttgtagttgc tgtctggtca actggcatat ccaaatgaat
      841 tgggaaagtc acaccttctg cttgtaaggc tgatttagct ttagcaaatt cagccttggc
      901 tttttctgga ttgtaaagac catcctgaga atctgcaaga ttaacatcct tccattcatc
      961 cccataagtg accaatttct ctttgaccat atcgccaaag tttttaccat ctgcttgaac
     1021 aaatgttggt ggcacaaaga tattacgtaa gattttgctt gctccagttt gtccattcaa
     1081 ctgagaggca taggctgtac gatcaaaacc aaaggcaata gcctgacgga aatccttgtt
     1141 taagagagcc tttttagtcg atgccttttg ttcatcgctg gtcttagatg tgtatttata
     1201 ggactgacgg tcaatatttg taccaactag atacgtaata gagtcttgtt gagtatagac
     1261 aatattgtcc ttcatactct tctcaagctc tgcgaaactt gcacttgttg gatagagacg
     1321 agctgctgta aggctaccat ctttaaagtt ttctgcaggt ttgctggtat cttgaccatc
     1381 ccagaatgac aatttaactt tgtcaacatg cacattgtcc ttatcccagt agttcggatt
     1441 tttcgcaaat tcaacagagg atttggtcac aatggatttc aacaaataag gaccgttata
     1501 caagagacta cttggatccg tagctttggc aaaatcatct ccttttgaat tcaaaaactc
     1561 ttcattaact ggcgcaagca cacccatggt tgtcttagaa ttccagaagc tttctggttt
     1621 gttcaaagtg tactgaactg tctgttcatc cagagcctta attcctactt gtgagaaatc
     1681 tttgatttcc ccttttacat aggcatccaa ccctttgatt gattcttgaa caaggtaaag
     1741 agcatctgat tttttatcag cagcatattt taatcctgtt acaaagtctt gagctttgac
     1801 tgccgcgtat tcttcacctt cagaagtata ccattttgca tccttacgga tagtataagt
     1861 gtaagtcaat ccatccttgg atacagacca atcctcagcc atagacggca caaagttccc
     1921 gtagcgatca ttttctagca aaccatcaac cacgttactg gtaatatttg ctgtcgcagc
     1981 cttagcagtt gtcaaatagt tgaggttatc agggtctgtc tcataaatgt atgagaatgt
     2041 cttctcacct ttagtgcttg aacctgatcc agagcatgca gctaaagtag tcgccgccaa
     2101 taatgtcacg cccgcaaggg caagtagtct tgaacttttc atcattttct cctttaaaac
     2161 tttctctcta ttatagactc ttttcagaga gatgtcaata taattttctg aattttttaa
     2221 ttaatttggt aaattctgaa aaatactttt aaggatattc taaagtaata actattcggc
     2281 tctcttgcgc ttcactaaca aagtttatac caaaaaaggg ttcactaaaa accgattttt
     2341 ctatattttt gatataatta agtataagaa ctatcaagga gaaaaatatg atcttaatta
     2401 caggtgcaaa tggtcaactt ggtaccgaac tacgttattt actagatgag cgaaatgtgg
     2461 actatgttgc agtggatgtg accgaaatgg atatcactaa ttctgaaatg gttgaaaaag
     2521 tctttgctga ggttaagcca actctagtct atcattgtgc agcctacact gctgttgatg
     2581 cagccgaaga tgaagggaaa gaactggatt ttgccatcaa cgtaactgga actgaaaatg
     2641 tagccaaggc ctctgagaaa tacggagcta ttctggtcta tatctcaaca gactacgtct
     2701 ttgatggaaa gaaaccagta ggacaagagt gggaagtcga tgacatacct gatccgcaaa
     2761 cagagtacgg acgtaccaag cgaatgggag aagaacttgt tgaaaacctt acgtcacagc
     2821 attacatcat tcgtactgct tgggtttttg gaaattatgg aaaaaacttt gtctttacca
     2881 tgcaaagcct agccaaaacc cataaaacgc tcacagtggt caacgaccaa tacggtcgcc
     2941 caacttggac acggaccttg gccgaattca tgacctatgt gactgaaaat caaaaagagt
     3001 atggctacta tcacttatca aatgacgcag ctgaagacac cacttggtat gactttgcta
     3061 gcgagattct taaggacagt gatgttgaag tagtgccagt agactctagc aagttccccg
     3121 ctaaggctaa acgacctctc aactcaacta tgagtttggc aaaggcaaag gcaacaggtt
     3181 tcgtcatccc aacctggcaa gatgccctta aagagtttta taaacaagaa gtaagaaaat
     3241 aaaagcttac tacatactag aaaagcaaga gacctcgagg tctcttgctt ttttagtatc
     3301 ttattattta atcacttgtt gcgttttagc atagttagcc tctactgctt ctttttcaga
     3361 tttccaccag tcttggttat ctgtgtacca cttgatggtc tctttgaggc ctgcttcaaa
     3421 gttggtaaac tctggcttcc accccaactc atcacggagc ttgctagcat caatcgcata
     3481 acgcaagtcg tgaccagctc gatcggtcac atggtcataa gcgtcagcgg gttgccccat
     3541 ctccttgaga atgagctcta acacttcctt gttgttcttc tcaccgtcag caccgatcaa
     3601 gtaagtttca ccgatttgac ccttggtcag aatcgtccaa acgcctgatg aatggtcatt
     3661 ggtgtgaatc cagtcacgca cattcttacc ttctccgtag agttttggct tgataccgct
     3721 caagatattc gtaatctggc gcggaatgaa cttctcgata tgctggtatg gaccatagtt
     3781 gtttgaacag ttagaaatcg ttgctttaac accaaatgag cgcacccaag ctttaacgat
     3841 caagtctgaa gcagccttgg ttgatgagta aggcgagctt ggattgtact tggtttcagc
     3901 ggtaaatttc tcacctaggc cttccccatg acctggcaaa tcttcacgca gaggcaggtc
     3961 accatagact tcatcagtcg atacatggtg gaaacgaatg tcgtatttac gagccgcttc
     4021 taaaagtgtg taagttccga taaagttggt gtggataaat ggactcgggt cattgagcga
     4081 gttatcattg tggctttctg ccgcatagtg aacgatagca tccgcttcag ccgccaactt
     4141 gtctaccaag gctgcatcag caatatctcc aacaaccaac tcaacacggt cgcctaaaat
     4201 ttcctcgata ttggcacgat tacctgcata agtcagcttg tccagcactg tcacatggac
     4261 atctggaaag ttattgtaaa catagtggac aaagttagaa ccgataaaac cagctccacc
     4321 tgtcacgata atttttttgt attcagtcat aatgtttcct tttacaactc gtctttcgta
     4381 agtggtttga catcccttaa tagaggatgg tgtttgtctg cctctgaaac ctcagcttcc
     4441 gctagatttt cccactcaat tcccaaggat gggtcagcat agttgacaaa ggcatatttg
     4501 ggttttagtt caagagccca gtagtcattg accagatagc tataggaaac tgtatccgag
     4561 aggacttgga aaccattggc gacgccacga gggacaaaaa ttcccttgct agcatcaatc
     4621 tctgtctggt aaacatttcc aaaagtctcg ccttcacgca aatccaccca agatcctaaa
     4681 accttcccat cgtctgcaac agagatatac ttgtcccaag gttctgcatg caatcctcga
     4741 agaacatttt ttcgagaaaa gctgacgttg ttttgcaatt tccctgcaac aaagaagctt
     4801 tcaggaaaac caagcggtag catcttttcc ttctggaagt tttccttaaa ccaaccacga
     4861 ttgtctccat gaacgggaat gtcaaactct agcagtcctg gtatagcatc aaccttgcgt
     4921 accgcaagtg tctttccaaa aaaattatct gacatctatg cttctccaat caaacggagc
     4981 aaatattgtc cgtattcatt cttcttcaga ggttgcgcca actcgagcac atcttcacga
     5041 ctgatatagc ccatgcgata ggcaatttct tccaagtttg caacttgaac attctgcata
     5101 cgctgaaccg tttcaatata ctgagaagct tctagcaggc tttcatgggt tcccgtatcc
     5161 aaccaggcaa aaccacgccc catcagctca acagaaaggt caccacgatt taggtaaacc
     5221 ttgttgatat ctgtaatttc taactcgcca cgtgcacttg gtttaatacc tttagcaatt
     5281 tctacaacat cattatcata gaaatacaga ccggtcacgg catagttgga gcgaggattc
     5341 tctggttttt cttctatgga aatggcattc atatctgtat caaactcgac cacaccaaaa
     5401 cgctctggat ccttcacttg gtagccaaaa acagttgcac ctttctcttt ctgggctgcc
     5461 ttttgaagca ttttgctcaa accaggtcca tgatagatat tgtcgcccaa aatcaaggca
     5521 acactatcgt caccgataaa ttcttcaccg ataagaaaag cctgagcaag tccatctgga
     5581 ctaggttgtt ccgcataaga aagcttgatc ccaaattcgg aaccatccaa gagcaagtcc
     5641 ttaaaccggg gcaaatcttg aggagttgag ataatcaaaa tatctttaat tccagccaac
     5701 attaatgtcg acaacggata ataaatcata ggtttatcat aaaccggcat cagctgtttt
     5761 gacgcagccc gagtaagtgg gtacaggcgg gtacctgagc cgcctgcaag aataatacct
     5821 ttcataatag tgtacctttc ttttttgata agtcttttac tttgacaaac cactaggagg
     5881 aaagtaaatt ttaattgtcc atactaaatt gctattaaca tttcaaggtc atatccctaa
     5941 gtttataaat caataaccta gagaatcata taattccttc ccacatctct ttcacagttc
     6001 taaaagtata agtaggcttt atactccctt gttgaatatc atcagctgtt gcttctcctg
     6061 ttaatacaca tactgaggat actcctgcat taatacctgt catgatatcg gtgtataaac
     6121 gatcaccgat tacaaccgtt tctgacaaag agtaattcaa tttttttcta actatgttaa
     6181 ccatcgtcgg ttcaggttta ccaatataaa taggagtttt atcaactgat ttgctaatca
     6241 tttcgcaaat cgaaccacaa tctggaagaa aaccaaagga aactgggcaa cgaacatctg
     6301 gattcgtggc aatgaatggg acatctctcg ttgacaaaac ttcacaggta ttacggattt
     6361 tctcacttgt tagttctgta tcaaaaccaa ctaaaacaag atctatgtta tctctcactt
     6421 gatcggtaac atcgattccc gaatcggata gttcttttaa caatgatttc gttccctgac
     6481 aatacacctt tgcgtgagga tatttttcct cgataaaaac aatcgttgct tgagcagaag
     6541 taaaaaaatt ctcccgttta gccacaatac ctaattggtt aactttttca atatagtcaa
     6601 caactgactt tgaggaattg ttcgtaataa aaatatactc accaccaata ctttgaatat
     6661 attctaataa ctgaagtgtc ccatcaaaca atctatcttc ttcataaatg gtaccatcca
     6721 tatcaaataa aaataatttt ttattcttta agtcactgat atccatccca aaataatcaa
     6781 ctttatttat caaatctgtc ctccctattt gttttaagca aatagttttt cagctgcagc
     6841 aagatcttca tgattgtcaa tttccaacca acgcccatcc agcggacaag ctacgaattc
     6901 aacagcttgg agaatcgcat taagtgcgac ctcgctccac agttgaagct catttttatc
     6961 ttcaatgaac tctctacatt tttcaaagaa acaagctcct gcatcaggag aaaatttata
     7021 aacatcaata gaagctccta aagcctcctc aggtgaaatc tgtttagaaa tttctactaa
     7081 acgaccattc ttttctacga ctttcataga ttcatcaatg taggttccta aatcagttac
     7141 aattgcgttc ggagcttcat gaagtaacaa acttttaatg acggaagcat cataaaacac
     7201 atctgcattc atcattaaga attcactact ccccattgca tctttaccta gataggctga
     7261 gtacatatta tttgttattt tataatcaac attatcaata atcttaattt cagggtattt
     7321 cccggaaatt acatccttta atactgatgc cttatagcca gaaataattg tgatatctgt
     7381 tacatcattt tgatataaat tttcaatttg ttttataaga ataggttttc cattaacagg
     7441 aactaatgat tttgggacgt cattagtgat aggagccaaa cgtgttccta aacctgctgc
     7501 taaaataagt gctttcattt tttcctctct tttctacaac tcatttacta attctttata
     7561 tatttgtttc accctagctg tgcttaaatc agcttcatga agatatgtat agcgattatt
     7621 tctcattgtt gtagcatgtt gcatacaata aacaaatagg tcttcatcga ttcccatttg
     7681 ttttggattg atatttacct caaatctttg caagtaatcc gtcactggtg taatcggatc
     7741 ttcaattatt tttaatactg caactgtacc taatgcaacc tgaataccat gaaggtttct
     7801 cttggaacca taataatcca aggcatgact aaataagtgt tctgaaccac taactggtct
     7861 actacttcct gcaaaatcca ttgcaatacc tgataaaact aatgaattta tcaaaacttc
     7921 aatgaaatca ggcgtaatag aattatactt tgttttcatc aaagcgtcca aggagttttg
     7981 ggacattaaa taggcaaagc catgcatttc atccttgcct cggttaacag ctaattccca
     8041 atctttcaac gccgtataat ttgaaatcgt atcaccaatg cccgctttaa tattctgtat
     8101 gggtcctgat gcaataacat caatatcgat aagagtcata gatggaattg ccgcacccaa
     8161 acttttaggt ctatcatctt gtcttttcaa aactgctact ggagaagcta tcccatcatt
     8221 cgctgcagtg gtgggaattg ataaatatgg ccgttttgaa atataagatg catatttaca
     8281 aacatctaaa acgcgaccac ctcccattcc cacaatacaa tcaatatctg ttgcaataac
     8341 tcgctcggct atattcattg cgtaagcaat cgtattataa ttacaacttt cttcttttaa
     8401 tcgacctatc tcctcaattt gtgacctaac taaagagcca tatagattgt caacaattgg
     8461 atcagcacaa tatagaatct tacctgatat attattttga gcaagtgtag aggatatttg
     8521 atgaatagcc ccactgccta tttttaatac attatttttc aaaccttttc acctaaaaaa
     8581 taattcaatg attttcttta caattcttga attattctcc ttcctatatt ttcactagct
     8641 cttccattaa acattggact aagggttcca tttctatatt gatttatagc agcataatca
     8701 aaatcattta ttttttcagg caggagggta tacagttcct ccgatgtcga aatgatagtg
     8761 tcaggtagct cataatatgt atccgataat cctctaagtt tagaatattc ctcaagatca
     8821 ttcacatatc ttacatacgg cttatttaag agtataaaat caaatataga tgaagaataa
     8881 tctgttagta gaacatctgc caacaatatg agttcctgca tatctgaaaa gaatgtaaca
     8941 ttaattatat cctgattaaa taaaatattt ctacaaaatt gtgagtggtt aggatgcaac
     9001 ctaattaata atttacaatt ctttctaatt cctttttcca cactctgtaa caggcgtaga
     9061 aaatctaaat tcaaatagga tatatcacca ttatctctaa aagttggtgc atataaaatg
     9121 acaaaatcat cacaggagat attaagttct tttcgaacat tttctaactt attataatcg
     9181 tctttacaat gaaacaagga atcatttctt ggcatcccta cctcaagaat ttcaccagta
     9241 taccaaaaat attttctgta ttcctcagtt tgcttcttac tgtctgaaat cattaaatcc
     9301 gtcactcgtg catcatattt agcttccaga acatagttca aaggtaattc agcctgtttt
     9361 tctatcagtt taaaacttga agcaccatgc caagtctgaa tataaaattg ctcttttctt
     9421 tttagtatcc tagcaaacgc cctcacatta tacacccata cttttgaact agcttgttcg
     9481 taaaaagctc gaattgaacc atattttact agtctgactc catctggaaa cccttttgtt
     9541 tctttagtga gccatactaa atctaattct ggatatgtag ttcttaggta ctcgcaaata
     9601 cttttaggat tatcaccata acccttccca ttgaaattaa taaatagaat cttattattt
     9661 tttaacctga ca
//
LOCUS       DAVLMQ010000063         9062 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000063 DAVLMQ010000000
VERSION     DAVLMQ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.063"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(71..304)
                     /locus_tag="VXF95_001867"
     CDS             complement(71..304)
                     /locus_tag="VXF95_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HEV1082369.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            complement(310..1302)
                     /gene="plsX"
                     /locus_tag="VXF95_001868"
     CDS             complement(310..1302)
                     /gene="plsX"
                     /locus_tag="VXF95_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HEV1082370.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVRLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTFPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLAADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLSGLKKQLN
                     YSDVGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            complement(1299..2069)
                     /gene="recO"
                     /locus_tag="VXF95_001869"
     CDS             complement(1299..2069)
                     /gene="recO"
                     /locus_tag="VXF95_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HEV1082371.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            complement(2066..3235)
                     /locus_tag="VXF95_001870"
     CDS             complement(2066..3235)
                     /locus_tag="VXF95_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HEV1082372.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKAVILNYPANPTGITYSREQLEALAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQAIIINGLSKSHAMTGWRLGLIFAPAAFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            3384..4394
                     /locus_tag="VXF95_001871"
     CDS             3384..4394
                     /locus_tag="VXF95_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HEV1082373.1"
                     /translation="MSFLSKNGAGILVCLLISILSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDVGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNTLESATIVKLT
                     RTLAIIPITLFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            complement(4599..4679)
                     /locus_tag="VXF95_001872"
                     /pseudo
     CDS             complement(4599..4679)
                     /locus_tag="VXF95_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4714..5151)
                     /locus_tag="VXF95_001873"
     CDS             complement(4714..5151)
                     /locus_tag="VXF95_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HEV1082374.1"
                     /translation="MSQEFINPSDGVIRRYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLLDVARDFLKADA
                     KIFWAQLGLESLEAEEILRAGGCDDIVMNRCIKREHTRLIGEA"
     gene            complement(5236..7869)
                     /gene="polA"
                     /locus_tag="VXF95_001874"
     CDS             complement(5236..7869)
                     /gene="polA"
                     /locus_tag="VXF95_001874"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HEV1082375.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVAKGLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCEDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYVQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDDVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKSYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            8125..8475
                     /locus_tag="VXF95_001875"
     CDS             8125..8475
                     /locus_tag="VXF95_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HEV1082376.1"
                     /translation="MLRHPCISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWTYLCSQVN
                     QNLEKIRQREGDTH"
     gene            8690..8806
                     /locus_tag="VXF95_001876"
     CDS             8690..8806
                     /locus_tag="VXF95_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HEV1082377.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGGQENV"
     gene            8799..9032
                     /locus_tag="VXF95_001877"
     CDS             8799..9032
                     /locus_tag="VXF95_001877"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082378.1"
                     /translation="MFSQLHMREEQVLLAQDYALETARAEGLEQGLERGKVEGREERK
                     LFAFLDIVRQGLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         2542 a         2267 c         1703 g         2550 t
ORIGIN      
        1 ttttaccagc ttgtccgata tttctcattt ctaaaaacca tctacttccg ttgacttgga
       61 actccgattg ctattttcct tgaatgattt taaccacatc tcctacgttt tggagttggt
      121 caatttcttc atcgctgatt tcgatactaa attcatcttc cagagtcaag ataaactcca
      181 tcaagtcaac agaatccgca tccaaatcgt ctttcagact caaggattct gtcacgacaa
      241 agtcctctcc ctgtcgctct tggataatgg tcacaatacg gtcaaaaatt tctttttctg
      301 tcatctcttt tattctcctg aaaattcacg cgcagtctgg gcaaccacgt ctgtttctag
      361 catggtacgg atctgacgaa tcgtactata aacagccttg gcatcgcttg agccatgagt
      421 cttgacaaca ggtgccttaa caccaaacaa gaccgctcca ccaacatctg aataattgag
      481 ctgttttttc aaaccactga ggctgtcctt gagaaggagg gcacctagtt tcgctcgaag
      541 accaccacct gtaatagctg tcttgagcaa gcccatgatt cccatagctg tcccttcgat
      601 ggatttgagc acagcgtttc ccgtgaaacc atctgccaca acaacatctg caacgccatt
      661 catcaaatca cgcgcttcca cgtttccgat aaagttcaaa ctttcatcag ccgccagtaa
      721 ttcataagtt tccttacgaa gcgggtcgcc cttgctactc tctgttccgt tgttgagcaa
      781 accaacgcgt ggttgcgcaa tgccacggac atttttagca tagaaggaac ctagaaccgc
      841 atattgatgg aggtgctggg ctgtattttc tgcattggca ccaaggtcta gcatgtcaaa
      901 accttttcca tcaacggtag gaaaggtaga catgagtcca ggacggtcga tattcttgat
      961 acgacccacg atgaagaatc ctgctgccaa caaggcacct gtattcccag ccgaaaggac
     1021 agcgtctgct tcaccatctt tgacagcctt ggctgccaat accatactgg catttttctt
     1081 attcctaata gctctcgtag gttcatcatc cgaatcaatc ttctcatccg tatggataat
     1141 gctgacgcgc tctgtcgctg tcagatattg cttgatttta gcttcatctc cgtaaagtcg
     1201 aacctcgata tctgaaaagt cagatagggc ttgattgaca ccctcaacaa tggcctgagg
     1261 tgcgtaatcg ccccccatgg catctactgc gatttttttc atttcttttc ctcttttagt
     1321 aattgtcccc agtctgctag ggaatcaata aatttctttg attttaggtg aatcccaacg
     1381 tactcttcat ataattgatc cataaattgg cgtagctctt gcttgattcc aggcttgagc
     1441 gaaatggtct ccaaagtctc aaaatcaata gcttgaaatt gattgagcag ataggggata
     1501 ttgggattga gatgacaacg tctcttatcc tcatgataat gctctggaca gaggcaggct
     1561 ccatatttga aagaaaagtc aaaagcctga ccaacccgat ggcagaagac acactcatta
     1621 aaattgaggc tgattccaaa tcgagtcaaa atttgaattt caaaaatatt ggtcaaaacc
     1681 tgataatcca agcctgcttc catcaactcc aaagtctttt gcaaaaaagc aaacaaggga
     1741 gcatcctgct gattgtcctg caaactagca tctgcaagag ctgccacata ggtcgcatag
     1801 gccatgacaa agaggtcact attaatcttg ggaaaagtca tgacctcatg atagtcttcg
     1861 atgtaactga gtccgtcatc attgattcgc aagagaaatc gtgccagcac caagggctga
     1921 ataacaggcg ccagcttaga ctgaccagcg tgtttgacaa aaaacatgcg tttgccaacc
     1981 tgctctgtaa aaattttgac gagcttgtca tcctcacgaa aattgcgatt gtaaagcacc
     2041 aagccttgac tcgtgataga ctgaatcatg cttctctcat gtactcctca agtcgtttca
     2101 tggcttcttt gatagtctcc atgctggctg cataagatag gcggacgtag ccttccccgt
     2161 aacgtccaaa ggctgcacca gggataaagg caacggcctt cttctgagca aaatccttca
     2221 gaaaagcaaa ggagtcttga ttgtagcccg ctggaatttt agcaaaaata tagaaggcac
     2281 cgtctggttt gataatctca aaaccaagag cagtcatttt ttcgatgata tagtcccgac
     2341 gctggatata ttccttcttc atgggctccg catcattttt accagccgtc aaggcttcta
     2401 ccgcagcatg ttgcgccatg gtatttgcgg cagtgaccaa gtattggtga ctcttgatta
     2461 actgggctgt gaaggccgca ggagcgaaaa tcagccccaa acgccaacct gtcatggcat
     2521 gcgatttaga caaaccattg ataataatag cctggtctct caacatcgtt cctagagaca
     2581 catgggcttc gcctgtgtag gtcaattctg agtaaacctc atcacagaca acaaaaattt
     2641 cgtacttgcg taaaacagct gccaaggcct ctaactgctc tcgactgtag gtaattcctg
     2701 tcggattggc tggatagttg agaataaccg ccttgagctt atcaccctgc tccaaaatgg
     2761 ccttctccaa catctcagga gtcaagacaa aaccattttc agtcgtatca atctcaacaa
     2821 tttctgcccc aactaagtta acaatcggtt catagcctgg ataagcagga gctggcaaaa
     2881 gtaccttgtc tccctcttcc aaaatagccg tcaaagtcgc agataaagcc tctgtcgccc
     2941 caattgtaac caagatttca ttttcaggag catagtccag ttggtacttt tccttaacaa
     3001 agtcactagc tgcctgacgt agagtcagca gaccactcat ccctgtatag taggattggt
     3061 tctgatcaat cgctcgcttg gccgcctcct tgacatggtc tggcgttgta aaatcaggtt
     3121 cccccaaggt caaacgcaag accccaggaa tctccgaaat agcctggtca aactgacgaa
     3181 tcaacgaaac ttgaatttta tctaactgtt tattaaagcg cttagttaag tccatagata
     3241 cctcctactt tcaaaacgta tctctattat actacaaaag ccccccgacc gcaaaaatac
     3301 attagagaat agctttccac tttctatttt acttttcctc tttacaggtc tataatggta
     3361 acagattcta tttggaggtt tttatgtcat ttctatcaaa aaatggagca ggcatcttgg
     3421 tctgccttct catttccatc ctatcttggt acttaggagg attcttccct gttattggcg
     3481 cacccgtttt tgcgattttt atgggaatgc tcctacatcc ctttctctcg tcttataaac
     3541 aactggatgt tggattgacc tttagttcca agaaattgct ccagtatgcc gttatcttac
     3601 ttggttttgg tctcaatatc tctcaagtct tcgcagttgg gcaatcttca ctccctgtca
     3661 tcctttccac catttcaata gccttgattg ttgcctacct cttccagcgc ttctttgccc
     3721 tggatacaaa actggctacc ttgattggag taggttcttc tatctgtggg ggttctgcca
     3781 ttgcagcgac agcgcctgtt atccatgcta aggaaaagga agtagcccaa gccatctccg
     3841 ttatcttttt cttcaatgtc ttggctgcgc tcatctttcc aaccctcggc acctggcttc
     3901 atctatccaa tgacggcttc gccctctttg caggaactgc ggtcaatgat acttcctctg
     3961 taaccgccac agctagcgct tgggacagtc tctaccagac caataccctc gaatccgcaa
     4021 ccattgtcaa actcacgcgc accctagcta tcatccccat cactctcttt ctctcctact
     4081 ggcaaagtcg cgagcaaaaa aataagcaag gcttacaact gaaaaaagtc ttcccacttt
     4141 ttatccttta cttcatcctt gcatcgctcc taaccaccct tctgacctct ctcggtgtgt
     4201 ctagtagttt ctttacccct ctcaaacaac tctctaaatt cctcattatc atggccatga
     4261 gtgccatcgg tctcaaaact aatctggtcg ctatggtcaa atccagtgga aaatccattg
     4321 ttctcggagc cgtctgctgg attgccatca tcctcaccag ccttggtatg cagaccctta
     4381 tcggcatttt ctaatactct tcgaaaatct cttcaaacca cgtcaacgtc gccttgccgt
     4441 aggtatatgt tactgacttc gtcagttcta tctgcaacct caaaacggtg ttttgagctg
     4501 acttcgtcag ttctatctgc aacctcaaaa cggtgttttg agctgacttc gtcagttcta
     4561 tctgcaacct caaaacggtg ttttgagctg acttcgtcag tcgtatctac aacctcaaaa
     4621 cagtgttttg agcaacccgc agctagtttc ctagtttgct ctttgatttt catttagtat
     4681 aacacaaaag gtagcccatc agctaccttt ttcttatgct tccccaatca agcgtgtatg
     4741 ttctctcttg atgcaacgat tcatcacgat gtcatcgcat ccaccagcac gcaagatttc
     4801 ttccgcctct agactttcaa gtcccagctg cgcccaaaaa atcttggcat cagccttgag
     4861 aaaatcacgc gccacatcga gcagaaattc actgcgacga taaacattga caatatctac
     4921 aggaaaagga atttcagcga ggctagcata agccttttca cccaagattt cgccacctgc
     4981 cgccttggga ttgactggga tgattttata gccccgagcc tgcatttcct ttgtcactcg
     5041 attgctggtt gtttcttcac ggtcagacaa acccaccaca gcaagggttt tactcgttgc
     5101 gagataccga cgaatcacgc catcacttgg attgataaat tcttgactca tagaaatcct
     5161 cctttttcat cagtatagca tattttgaaa aggtttgcag aattctacta caaaaaagga
     5221 ggactagccc cctttttatt tagcctcgta ccaggttgcc ccttcattct catctgcgat
     5281 aagaggaaca ctgagttgaa tggcttcttc catggtttgt ttcaccaatt ttttcatctc
     5341 taccaattca gatttaggca cttcaaggac gatttcatcg tgcacttgta acagcatctt
     5401 agtctgataa ccacctgcaa ccaaggcttt atccagctga atcatggcaa tcttgagaat
     5461 atctgctgcc gaaccctgga taggtgagtt gatagcagtt cgctccgcaa aaccacgaat
     5521 attgaagttg cgcgaattga tatctggcaa ctcacggcga cgcttaaaga gggtctctac
     5581 atagctctta tcacgcgcct cccgcaccac ttcatccatg tagtttttaa tacctggaaa
     5641 acgttcaaag taggtatcaa tgtaggcttt ggcttcctta cgactaattc ccaaattatt
     5701 agacaagcca aagtctgaaa tcccataaac cactccaaag ttaactgcct tggcattgcg
     5761 acggtcgttt gcagtcacat catcaggacg ctcaatgcca aagacccgca tggctgtcga
     5821 agtatggata tctgccccct cttggaaggc cttaatcaag tgctcatcct tagaaatatg
     5881 cgccaaaacg cgcaattcaa tctgtgaata gtcagagctg agtagcacac tatcctccca
     5941 ctctggcaca aaagccttcc gaatcaagcg cccctgttcc aatcgggcag gaatattttg
     6001 caagtttgga tccacactag acaaacgccc ggtctgggtc aaatcctgca catagcgagt
     6061 atgaatcttt ccatcagcca aaatccagtc ctgcaagcca attacataag tagattgaat
     6121 cttagcaatt tgacggtaat ccaggatttt cttaacaatc ggagcaatag gagcgagacg
     6181 ctccaacaca tccactgctg tcgaataacc tgtcttggtt ttcttagtgt attctagagg
     6241 aagtcccaat ttctcaaaga gaagcacgcc caactgctta ggcgagttga cattaaactc
     6301 ctcaccagcc agctcgtaaa tctcttgagt cagtttttca atgacaagct cattttcagc
     6361 ctgcatctca agcaaggtct ctttcttgac cataatccca gcaatttcca tcttggcaag
     6421 gacaaaagcc agaggttgct ccatatcata aagaagctct aattgcccat tttcgctgag
     6481 tttttcaagt aaaataggct ctgtttctac caaaacagca agtttacaag ctaagtgttc
     6541 caagaatttc tcacgttcag gaatggcctt tttaacaccc ttaccgtaga aagtttcatc
     6601 atcaaccaag taagtctgac cataaagact agcgatggtc gcaatttcat tgtcctccac
     6661 agtcgaaagg aggtatttag ccaaacggat gtcaaaagca ggcgcctgca aatccacacc
     6721 aaaacgttgc aaaagaactt taaccttctt aaagtcataa actctcagag atgttttttc
     6781 taagaaatcc ttgaaaatcg ggtcttgcaa cagctcaagc ttgtctgtgg catagagctt
     6841 atcctcacaa gaccaggcaa atccaaccaa attatccgta tggtaattct caccaaaaag
     6901 ctcaaagtgg aagatagact cttcactcag catatcttga ctgatttggt caacaatagt
     6961 aaaatctaaa cccttagcca catcagctga cgacacattt aaagcctgct tgagctgttt
     7021 gaagcccatc tcatcgtaaa atttcccaag attttcaaca tctggaccac tatagaccaa
     7081 gtcctctaaa ccaatcgcaa tcggtgcctt ggtatcaatg gtcgctagtg ttttagacaa
     7141 aaaggcctgt tccttgtcat tgatgagatt ttccttcatc ttagaagtct tcattccatc
     7201 aatattttca taaatcccct caagcgaacc atgctccagc aagagcttaa tacccgtctt
     7261 ttcaccgact ttggtcaccc cagggatatt atccgactta tcacccatga gcgccttgag
     7321 atcgataaac tgagctggtg tgaggcccat ttcttccatg aggtaatctg gcgtaaaggc
     7381 ctcaaactca gccacacctt tcttggaaat ttcaaccacc gtatgctcat ccgtcagctg
     7441 aatcaaatcc ttgtccccac tgacaatggt aatatcaaaa ccatcctgct ctgctagctt
     7501 atccagcgtc ccaatgatgt catccgcctc atactgagcc agctcatagt gacgaatccc
     7561 catatgatcc agcaactcac gaatgaaagg aaattgctca cgaaactcat caggagtctt
     7621 ggcccgacca cccttatagt ccgcatacat ctctgtccgg aaggtcgtct ttcccgcatc
     7681 aaaagccacc aaaatatgac tcggctcaac ccgctccaac aaatgactca acatcaactg
     7741 gaaaccataa atcgcattgg tatgcaaacc agccgcattc ttaaaacggt ccaactgctg
     7801 atacagcgca aaaaacgccc gaaaagctac agaagaccca tcaatcaata ataatttttt
     7861 cttatccata cacccattat aaaggaaaga atcaaaaaat accattggga agagctagag
     7921 caagtatttt tcaaactttt tccgaataaa tagatagagc cagagaatct agtaaaccta
     7981 gatttaaaaa tgtgctataa tatagcatat tgaatctata atagtacatc ttgactgcta
     8041 aaatatttct ataaattaat ttgacttttc tgatagagtt gttcacatct tatttcaact
     8101 cactatagaa ggaggaaaag gaggattctc agacatccgt gcatcagccc aactaatgat
     8161 ttgattgcta agaaaatatt cagcaatcca gaaatcactt gtcaatttat tcgcgatatg
     8221 ctggacttgc cagcaaaaaa tgtgaccatt ttggagggaa gcgatattca cgtattactc
     8281 tccatgcctt actcggtgca ggatttttat accagtatag acgtcttggc ggagttggat
     8341 aacggtactc aagtaattat tgagattcaa gtccatcatc agaatttttt catcaatcac
     8401 ttgtggactt acctgtgcag tcaggttaat caaaatcttg aaaaaattcg tcagcgagaa
     8461 ggtgatactc actagagcta caaacacatc gctcctgttt acgccattgc tatcgtggat
     8521 agtaattatt tctcagatga cctggctttt catagcttta gtatgcgcga agacacaaca
     8581 ggtgaggtat tggcgattac caacaatgga caggaaaacc atctggttaa gatggcattc
     8641 ttggaattaa aaaatacaga gaaaccagca aagacaaggt tcgcaagcca tggttggagt
     8701 ttttcggcaa caagcccttt acccagcaac cgcaacgagc cattacccaa gcaaatcaac
     8761 tgctggacta caagagctgg tccgaggagg acaggaaaat gtttagtcaa ctacatatgc
     8821 gagaagaaca agtcttgtta gcacaggact atgccttgga aactgctagg gctgaaggcc
     8881 ttgaacaagg actagagcgt gggaaagttg aaggaaggga agaaaggaaa ctttttgcct
     8941 tcctagacat agtacgccaa ggtcttctga cttctgaggt tgccagccag caattaggta
     9001 tgtcagtatc tgaatttgag gcactgttgt aaaatggctc tataatattt gtagtgtgta
     9061 aa
//
LOCUS       DAVLMQ010000064         8976 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000064 DAVLMQ010000000
VERSION     DAVLMQ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8976)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8976)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8976
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.064"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(461..2740)
                     /gene="pulA"
                     /locus_tag="VXF95_001878"
     CDS             complement(461..2740)
                     /gene="pulA"
                     /locus_tag="VXF95_001878"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HEV1082379.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKTYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGYLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(2852..4810)
                     /gene="ligA"
                     /locus_tag="VXF95_001879"
     CDS             complement(2852..4810)
                     /gene="ligA"
                     /locus_tag="VXF95_001879"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HEV1082380.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTNLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(4903..6081)
                     /locus_tag="VXF95_001880"
     CDS             complement(4903..6081)
                     /locus_tag="VXF95_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1082381.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQAIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLW
                     RVLSTIFTLAILFMPIAKGFMTVLQSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(6161..7024)
                     /locus_tag="VXF95_001881"
     CDS             complement(6161..7024)
                     /locus_tag="VXF95_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1082382.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(7027..8928)
                     /locus_tag="VXF95_001882"
     CDS             complement(7027..8928)
                     /locus_tag="VXF95_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HEV1082383.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNDLRRTDKQLR
                     QMELEMGEKSGEDLDKLMSDYDHLSENFRQAGGFTYEADIRAILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETISWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLATEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEKTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQVQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         2704 a         1975 c         1616 g         2681 t
ORIGIN      
        1 attttcacaa acttgatttt tcaaagtata ctcaataaaa attaaaaaaa tccactacgt
       61 caaggcgagg ctaatgtggt ttgaagaaat tttcgaagag cgtgaatgag tatcatctat
      121 agtaaaataa aaaaactgaa caatttggtt ggggacagcc aaaccaattt ctcacaatgt
      181 tttagaaaca agggtgtgct attccaattt caggctacta taactgtcat agattgctga
      241 aacaaagtct aggtaaaagt cttcataata aaaagacccc ctatcaagtg ttcaaaaact
      301 ttgataggag gtcttgtttt gtgaaaatat ttatcaaatt ttctatacaa gtgagctgtt
      361 agccaggttc tttctattct ttcaatttca atgaatggat tttttactaa tactcataac
      421 tgggaatttg tctgtgtaaa aatagcgaga tagatggtat ttataaaaca ctcaagacag
      481 ctagactaat atcatttaaa acattatctt cttttgagcg actgttggtt accaacatag
      541 ctaaatttcc tgcattttca aattgatagg gttctgattt agcattcaca accaccaaga
      601 gatgttcttt gccgtgaact tcatagataa ggtagccgct atgttcaatc gcagaatgca
      661 caaagacatg atggtaaatt tcatcatagc tagagtaaga aaaggcacca gtttttgtct
      721 tcaatcggat gacttgacgg ataaactcaa tactgtcttg acgctcatta atcaagttcc
      781 agttcacttg gttcacactg tcaggagcat tatagctatt catcgcacgc tctctatcat
      841 catgggtcaa ctcaccattt tcaccagtcg caaccagttt ggtacgacca aattcttgac
      901 cgatttccat aaaggccatc ccctgcatga gcagattcat ggctgtggca gtttcgacct
      961 tgcgcatgat ttgctctgaa ctttggtctg gatgaagggt tgccaataaa tcgtgaagat
     1021 tgtaattgtc atgggcttct acatagttaa gcacctgatt tggatgtgta tagcttccta
     1081 attcacgact tcctaggatt gctttagcta gaattggctc tgtcgcagca ccactgacaa
     1141 aacctgactt gatagcacca taaacttctc cccctttgac agcatcgcgc tgattgtcat
     1201 taaagaaacc aatatttggc atctggtagg cattgtcctt cttggcctta tcataagggg
     1261 caagacctgt tcccatatcc catccttctc catagaggat aatgttggag tcgatttcat
     1321 ccaagctttg acgaatcatc tgcatggtct tgacatcatg aatccccatc aagtcaaaac
     1381 ggaagccgtc aatattatat tcctgcaccc agtatagaag agaatcaatc atatacttgc
     1441 gaaacatttc gtgttcactg gctgtttcat ttccaacacc cgttccattc tggaaggtac
     1501 catctggatt catacgataa tagtaatcag ggactgttgt ttggaatggt gcatcaacaa
     1561 ctgagaaggt atggttatag actacatcca taatgactcc aatacccgca tcgtgataag
     1621 cttgaaccat caccttcaaa tcacgaatga cctgagctgg atcatctgga ttagttgaaa
     1681 aactagtttc tggcgcgtta tagttttgtg gatcataacc ccagttgtag gttacatttc
     1741 catcctcatc gtattcttta tgacggtctg caattggttg caattgaaca taattgtagc
     1801 ccagcttctt gatgtaatca aaagcagttg actggccgta ttggttaact gttccagcct
     1861 gagcagcacc caagaaagtt cctcgaagat gttcatctac acccgatgta ggtgatttag
     1921 tcaaatcacg aatatgcatt tcacagataa ctgccttaca tggattttcc aagcgccaag
     1981 tagcctccga accgtgctta acctcgaagt tttcaacttg cttttctaca tggctcagaa
     2041 tagctgaacg tttgccatca gggctggtcg cgattgtata aggatcacgt gtcagtgttt
     2101 ggtgatgagg gaattggact tgatactgat aagtcttacc taccaaatct tcttcaacat
     2161 ccaaactcca gacaccgatt gtattgtcct tatgattata agagtagcta ttgcctcttt
     2221 tcatctcaaa agtcttccaa acgggtgcat cattagcagc tgattcataa acgacaactt
     2281 gcacttctgt cgctgtaggt gaccagaggg aaaaatgagc ctgattgtcc tctacacggc
     2341 aacccaattc tccttggtaa ccccaatgat gatcaaaact agcactgtta atggccttat
     2401 caaaggcaaa aggattttga tttttataga aaggactggc aatagcagga ttttcagagt
     2461 aataaatcct atcatcgcct tccaaaatcc agacctctgt taatagggga tagtgattaa
     2521 aacggataga atattcttta ctagtttgac ctgtatgaac cacaaaattc aagctttcta
     2581 taacatgtga acttgggtgt tcaaagctaa ataaagctcc aaaataatct tctttgtagg
     2641 ttagcaaatc aattcgttga tcctgacttt ttacaaagga gcaagtgtca tattctccat
     2701 tcttacgatg gtaatgaatg cgcatagggt agttatacat tttttatttt tcctttttac
     2761 tttgtttcta tttcactaat aaatttttgt caatctcgtc tcaattaaca gacatagtca
     2821 tattctctaa actctgtttt taaacgatcc attacaaact ttctagccat gcctcatctc
     2881 tgacctggat accaagttct tgtgcttttt gcagcttact tccagcgtct gcacctacca
     2941 cgacgaggtt ggtcttttta gaaacactac ctgtcacttt ggcacccaga ctttcgagtt
     3001 tacttttagc ttctgagcgc ttgagtcgtt ccaattttcc tgtcaatacc acggtcaaac
     3061 ctgacaaggc cgcatccgct actaccgtct gtcctttata gtccagattg accccagttt
     3121 ctttcaattc tctgagcaga atttcagagc cttctgtcgc aaaataagtc tgaagacttt
     3181 tggcaatcac gccacctaga ctttcaatac tagccacttc ctctgaatct gcctgataca
     3241 gattttcaat tgaatggaaa tattgaagta aaagctgact agccttgctt ccgacatgac
     3301 gaattcccaa accaaataag agcttctcgg cagaattttc ctttgacgct tggatagcct
     3361 gatacagttt agcagcggac ttttccttaa ccccctctaa aaggaggaaa tcctcttctt
     3421 gcaaacgata aatatccgcc acatccttga ctaaattagc agcaaaaagc ttctcaacaa
     3481 tagatggacc aaggcctgta atattcatag catcacgaga agcaaagtga atcaagcctt
     3541 ccatgatttg agcagggcaa cgcggattga tacaacgtag ggccacttca tcttcaaagt
     3601 gcaacaagtc agagttacaa cttggacagt ttgtagggat atctagtttt tcttcagaaa
     3661 cccgtttgga ctctaccaca cgtaaaacgg cagggatgat gtcaccagcc ttatatacaa
     3721 tgaccgtatc gtcttttcgg atatcttttt cagcaatata atctacattg tgcagggtcg
     3781 cacggctaac agtcgtaccg gcaagttgta ctggtgttag attagcagtt ggagttacaa
     3841 caccggtacg gccaactgtc cagtcaactg ataagagttg agcttctttt tcttcagcag
     3901 ggaacttgta ggctactgcc cactttggag ccttaacggt aaaaccaagt tcttcttgac
     3961 ttgctaggtc gttgaccttg attaccactc catcaatatc gtaaggtaga ttttcccgtt
     4021 cctgtcctac ttcttggata aaattccaga tttcatctat gttttcagcc aagattcgct
     4081 taggattgac cacaaaacct agttgttcta ggtacttcaa acccttttct tggctatcac
     4141 gagttgaagg gctggcttct tgatagagaa acgttgcaag attacgcttg gcaactactg
     4201 ctgtatccaa ctgacgcaga gttcctgctg ccgcattacg aggattagca aattcaggct
     4261 ctccattttc ttggcgcgct tggttaactt ggtcaaagga agcgcgtggc atgtaacatt
     4321 ccccacgaac tgtgatatct agttcttctg gcaaagtcaa agggatgtcc ttaacacgct
     4381 tgaggttttc tgtgatattt tcaccaattg aaccatctcc acgtgttacc ccagcaacca
     4441 aaatcccctt ttcataagtc agcgagatag ataagccatc gattttcagc tcacaaatat
     4501 aggtcggatg agccacttcc ttacgaacac gcgcatcaaa agcatctagc tcctcacgtg
     4561 aaaaagcatc ctgcaaacta taaagaggat actgatgact gtatttttca aaaccatcta
     4621 aaaccttgcc accaacacga tgagtcggac tgtctgctag cacttgctct ggataagcag
     4681 tttctaactc gaccaactca cggtaaaggc ggtcatactc actgtctgaa accgagggat
     4741 tatcgctggt atagtactca gtcgcatagc gattgagcaa agcgactaac tcattcattc
     4801 ttttattcat aagaccattt taccataaaa caagccctcc tcacaaacga gaagggcgga
     4861 aaaaacactt agtttgaaat tatttttgaa actcaagcaa ccttatatca atttttcaaa
     4921 atgagttcga acataaataa acgatataca agacaagatg ataacaccac ttccaattat
     4981 caggaaagaa gagagatgta cactttgcaa gactgtcata aatccttttg caataggcat
     5041 aaatagaata gctaaggtaa aaattgtact cagtactctc caaagaaatt cgctctcaac
     5101 cttggtttgt acttgagtaa aaaagtgaat attaaaaatc gtcataaaca attcacaaac
     5161 taaatttcca gaaaaggaaa gaaaagttgg aagtggtaat cccatcataa aaactccaac
     5221 acctgtcaaa gccagtaaaa tcaaaagatt ataaatatta gctttaattt tactagctag
     5281 aagagcccca atgatggaac caatagcccc catagttaaa atacttgcat aggctccttc
     5341 tgacccgtaa agctgattcg aaaagggaag tagaaattca aaagctgcaa aaaagaaatt
     5401 aacgctggaa gctaccagca aaaggaagaa aatttcttgc tgatgccaga tatagtgtaa
     5461 cccatccttg atatctacaa aaatatctct cccagtaaaa gcctttttct cttgaacttt
     5521 tgcttcctct tttggaagga aagccactag aacaaaagca atgaaaaaag tcagcgagtc
     5581 tagcagtagc gtcatatgga gacttgcaaa ctgtaaaaca aggaaggaaa gaacaggaga
     5641 gctaacacct acaacctgca aaaccagctc taagcgagaa ttatagatca caatctcatc
     5701 tttctccacc acttcagtta tgatagcttt attggctgtg cgagaaaagg caaaagcaat
     5761 agcctgcaca atgttagcaa caatcaaagc gccaatcatc cagctatcat tccttatgaa
     5821 agaaatagcc agacaaagaa tcccacaaac aagatctgcc gtcattaaaa tcttacgacg
     5881 agaaaaacgg tctgaaataa ctccaccaaa gggattgacg agaatagatg tgacgagctc
     5941 agaaatctga tacattccta aaactgtctg tcctatagtc cccatagaag ccaaccagac
     6001 actatttcca taatcataga gcatatttcc cattttattg atagccccac ggctaatcaa
     6061 ctgcactgca tagcgattca tattaaagct cctctcaaat tttgaaacta ttgtatcaaa
     6121 accgaaagga gctttttatt ttttccctta tttgggaaaa ttaacttttg acaaattttt
     6181 cgtagtgttc ctgataatag gctacttgct ctggaagacc taacacatca aaaatatgca
     6241 tggcctcttg catctgctta cagccttctt tacactgtcc tttttgatat aaggccaaac
     6301 cttttaaata atggaaaaca ttacgctcat aaagcttaat acctttgtca ataatcttct
     6361 ctgtataagc ctcaaaatag ttggcattat aaaaagaaga atgctctaaa caatgctggt
     6421 aacaattgag ggccaaaatt aacactaatc tcttatggcg actaatctct tggtaaaatt
     6481 cctccctctc cataacttct ctaccaatcc gagtgacata gtctacatcg tagaaactat
     6541 agaggttacc gaaaagaatc aactcataca tggtccattc ttctgttttg aagagataat
     6601 ctgctacctt atccaaatca tcctgcttca tatcataact cgcatctctt tgacaaatca
     6661 gaccttgtag caaaatccag ttcagctcaa aataaagggg agtcgtcgaa ctcttagact
     6721 tttcaagttg ttctctttga agcttttgaa aacctgcaat atcgtttgaa tagtaaagtg
     6781 ggataatctg tgccatcata gacacatgtt catgattatg aaaattcctt gccttatcca
     6841 tgaaattttc gattgttaca tgaatgttat ccaaaatctc aaagaaacgg gagactgcca
     6901 ggtcagactc cccaagctca aagcgagata actgagaggt agagcaggat tcgcctgctg
     6961 cttcctttaa agaataattt ccacttgttc gaaattcacg aaatactttt ccaagatgtt
     7021 ccatctttac acctgctctg ataattcttc ccactcaagc atagcttctt cctgacgatg
     7081 gctgattttg tccagctcag cctgtaattc catgagtttg tcggcatcgt ttgtttccaa
     7141 catttgttca gaaatggctt ggctttgact ttctagctct tcaatttcag cttctagact
     7201 ttcgatttgt cgcatgagtt tgcgaacttc tttttgactt tctttctgga cctgatagtc
     7261 attgactgga cttgcttcct ttgcttgatt gctagttgaa gcttcctcag tctgactcat
     7321 ttctgctgtt actttcttct caacatagta gtcgtaatct ccaaggtaga gagttgaacc
     7381 attctcagac aattccaaaa catgagttgc cacacgattg ataaagtaac gatcatgact
     7441 gacaaacagc aaggtaccat caaagtcaat caaggcattt tctagcactt ccttactatc
     7501 aatatccaag tggttggtcg gctcatccag aatcaaaaag ttattgtttt ccatagacaa
     7561 tttagctaaa agcaaacgag ctttttcgcc accagatagc atgccgactg attttttaac
     7621 atcatctcct gagaaaagga aggctccaag acggttgcgg atttcaactt ctggtgtcag
     7681 tttgaaatca ttccagagtt catccagcac cgtattactt ggtgtcagct tgctttgggt
     7741 ttggtcatag taaccaacct caacattagc gccaaagcgc ttttctccct tgataaacgg
     7801 aatttgatcc acgattgatt tgataaaggt tgattttccg ataccattgg gaccaacgat
     7861 agcgacagca ttcatcttac gaagatctag gttgataggt tgtgacaaga cttccccgtc
     7921 ataaccaata gcagtatttt caacagtcaa aacaacattg cccgacgttt tttcagactg
     7981 gaaggtcatg ttggctgctt tcttgccagc ttcaggcttg tccaaacgct ccattttttc
     8041 tagttgttta cggcgagatt gagcacgttt agtcgttgaa gcacgaacta gattgcgatt
     8101 gacaaagtct tccagagcag cgatttcctt ctgttgcttt tcatagtttt ttgcctcagt
     8161 agctagcttt tgctccttca attcgacaaa acgagagtaa ttccccacat agcgatccaa
     8221 ggaatgcttg gtcaaatcta gcgtaattgt cgcaaccttg tccaagaaat aacggtcgtg
     8281 gctgacgata atgagggcac cgctatagtt taccaagtaa ttctctagcc aggagatggt
     8341 ttcaatatcc aagtggttag ttggctcgtc caagaccaag agattgggct tttcaaggag
     8401 cattttagct agagccaaac gagtattttg accacctgaa agttcagcta ttttcatctg
     8461 ccacatagac tcgtcaaact tgaatccatt caaaatcgct cgaatatcag cttcataggt
     8521 aaagccgcct gcttggcgaa aattctcaga taagtggtcg taatctgaca tcagtttatc
     8581 caaatcctca ccagactttt cacccatctc caactccatc tgacgaagtt gtttatctgt
     8641 ccgacgtaag tcattaaaga catgaagcat ttcatcgtag atggtatttt cagactcaaa
     8701 acggctatct tgggctaggt aagacagaga aatatctttt ttcttattga tttctccgct
     8761 agttggctcc tcttctccaa ctaaaatctt caaaagagta gacttacctg caccattttt
     8821 cccaacaagg gcaatccgat ctcgttcatc aacctgcagg ttgatattat cgaaaagaac
     8881 ctctcctgca aaagaacgtt caattttatt agcttgtaaa ataatcataa gagtagtata
     8941 gcatgtttcc ctaaggcatt caagataatc gtaagt
//
LOCUS       DAVLMQ010000065         8956 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000065 DAVLMQ010000000
VERSION     DAVLMQ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8956
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.065"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VXF95_001883"
     CDS             complement(296..1144)
                     /gene="dprA"
                     /locus_tag="VXF95_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HEV1082384.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            complement(1250..1939)
                     /locus_tag="VXF95_001884"
     CDS             complement(1250..1939)
                     /locus_tag="VXF95_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HEV1082385.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQDIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     RKLEEILKNEN"
     gene            complement(1951..2829)
                     /locus_tag="VXF95_001885"
     CDS             complement(1951..2829)
                     /locus_tag="VXF95_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HEV1082386.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VXF95_001886"
     CDS             complement(2819..3688)
                     /gene="licA"
                     /locus_tag="VXF95_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HEV1082387.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLAKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLIEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            complement(3705..4727)
                     /locus_tag="VXF95_001887"
     CDS             complement(3705..4727)
                     /locus_tag="VXF95_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HEV1082388.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRSRIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            complement(4732..5439)
                     /locus_tag="VXF95_001888"
     CDS             complement(4732..5439)
                     /locus_tag="VXF95_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HEV1082389.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFVDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            5775..7262
                     /gene="tacF"
                     /locus_tag="VXF95_001889"
     CDS             5775..7262
                     /gene="tacF"
                     /locus_tag="VXF95_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HEV1082390.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVAPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            7272..8075
                     /locus_tag="VXF95_001890"
     CDS             7272..8075
                     /locus_tag="VXF95_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1082391.1"
                     /translation="MKQLTVEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            8077..8886
                     /locus_tag="VXF95_001891"
     CDS             8077..8886
                     /locus_tag="VXF95_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HEV1082392.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKYDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNTPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
BASE COUNT         2813 a         1805 c         1511 g         2827 t
ORIGIN      
        1 tcactatact ttcccttata ctcaatgaaa atcaaagcac tgctttgagg ttgtagataa
       61 gactgacgaa gtcagctcaa aatactgttt tgaggttgca gatggaagct gacgtagttt
      121 gaagagattt tcgaagagta ttatatgaga aaaatcctct actctactaa tccacttaga
      181 aaaaacgcat attatcaagt gttaaaaact tgctaatatg cgttttatta tggaaatgtt
      241 gggttcattt tctcttaaaa ttgatttttt cttagaattc tagcttaggt catttttaaa
      301 attcaaattc cgcaagaaca tcttgcccac tggtgaccaa ttttgctcct tcttgaatca
      361 aatgatggca accgtctgat agtccatcta aaatgctacc aggaatagca aagacatcgc
      421 gtccttcttc cattgctcgc tcacacgtaa tgagactacc tgaacgcatc ttagcctctg
      481 ctacaatcac accacgacaa agtccagcaa tgatgcgatt acgggcagga aaatgaaatt
      541 tcagaggttg ttcgccaggt ccatattcac ttagaaccag atggtcattg ccgatgtagt
      601 cttgcaagcg tttattggct ttaggataaa acacatccag tcctgttcca atcactgcaa
      661 tggtttttcc gccattctga agagctgcca tatgagctgc tgtgtcaatg cccttggcca
      721 gaccactgac aataaccagt tcattttcca agccttgaat gactttttca actgacttag
      781 ctccctgttt gctacaagca cgactgccca cgaccgctac cttcgggaat ttcaggaggt
      841 caagatttcc cttgtaaaat aaaagtacag gcgcatcata tatttcactc aaatcccaag
      901 gataacagtc atctaaaata gagaaagatg gaaatttttg aaactctttc gacaaatgcg
      961 catcgtctat ctgaaaataa cgttccataa aaacggctgg attacggcaa cctgatatat
     1021 ctgcaatatc acccaacaaa agctcctgat caacattttc accgtattct agcactttca
     1081 aaatctgttg attggtcaaa cctgattttt ttaacttata gatttcatag tttgtgattt
     1141 tcataaataa ctccatttct ttttctactc atctatctat tcgtaaaagt tcgtaaaagt
     1201 tcgtaaaaaa tcaaaaaaca tccgactatt ttgccagatg ttggaatctt taattttcgt
     1261 ttttaagaat ttcttctaat ttacgatagt cttggacact atcgatctca taaatgctat
     1321 tgccttctaa ttcttcaaca tagacatcta gctctttgat attatcctta accatattgt
     1381 cccaatagag atcaacaaat tcaccacttg cataagcctt gtcgataaag ctgacaatct
     1441 tttctgcagt tggagcatcc cagaaggata caccactaag gatgcgacct gccttgctat
     1501 caacaataat gtcttgaacc ttgtagtcat ctccatagac caagaaccat tcgttggtac
     1561 aatcttcacg ataaacacta aaataagtcg aacgtgtcaa atcattgcgg aacatatttt
     1621 taaagagata attgtcagca tcaataacat agctgttggc caattcttct tttacaagat
     1681 agagagagta aaagttattg tagtcagcgt atttatcatt gaaaacgagg cgaacaccgt
     1741 atttttcttt taagtaatcg aattgttctt taagataacc aacaatgatg atgatgtcat
     1801 tgattccttt ttctttgaga aactcaattt ggtattcaat caaaggtttt tgattaacct
     1861 gaaccaaggc tttaggggta ttttcagtca taggacgcaa gcgagttccc aatcccgctg
     1921 ctaagataat ggctttcaca cgaatctcct ttattcttta ataataatat aaactccagc
     1981 aatgacgaca agtgacgtca taatggtcag catatctagc ggtgcaccca aaaaaacaac
     2041 tgcaaacaag accgtccata ctacatagct cacgttcaag cctgtagcct tggctggttg
     2101 caagcgattg atagcgatat aataagccaa gtaggaaatc atatcaaagg ctgcaaaaac
     2161 aatcatgaga cctagcaatt gtccattggc tactgcagta aatgactgat gagagaagag
     2221 cacaatcaca agataggaca agaacgaagt cacttgacgg attaagaggg cttcgatttc
     2281 actcagttca ctttccatag caaaggagct aagaacactc tcacttcccc atgcaatagc
     2341 acaaaccaaa gcacagagaa tcccaatgta gaaggaatta acctgttcaa ccttataggt
     2401 ctgggcaata atccctccaa taatcaagac aatcccaaat acagtatttt tcgaaatctt
     2461 gtgcttcaaa aagaagaaag ccaatagaac tgaaatcgca gggtaaatag ccgatacaga
     2521 tgaagctaaa gaacttccga tatacttaac tgcataaaga ttggcctgca taccgatagg
     2581 gcctgctagc aaggctccga tgataacact gacattgcga atatttaaga aaattgagag
     2641 gcgaactttc ccttctttta ccaagagaaa agctagtaag ataaagatgc tcaaaaaatc
     2701 atgagctgca gccaccacaa agggtgacaa atctgtaaaa atcgaaaaga tataagcact
     2761 aaccgttaga cccaagcccc agaaaatacc tgagagaagg ccaaaaggaa ctccgttttt
     2821 acttttcatc tgaacctcca taagaagcca aacctttaac agctctttgg taacgattca
     2881 caccatagtc accaaaatct tcaccttgct cttccttata gacagtccat agactccaaa
     2941 tagtatcttg taaaatttta taaatagcaa tcttttcatg agaaaccggt gtttggtcac
     3001 tctcatagtg agataagaaa gtttcttcct cttgggaagt gaattcagac tctaaaaaga
     3061 gggcagccaa atcccacatt ggatcattca ttgatgaata ttcccagtca atcaaataaa
     3121 gtcgtccttg aggtgattcg ataaagtttt caggcaccaa atcgatatga caagattttc
     3181 tgtcaacacc taagtcagcc agtcttttct ctaaggagaa gactgcattt ctaacagatt
     3241 catagttggc ataaggaatt tgttcttcaa tcaaggattc gtattttttg atttcttcaa
     3301 aaggagcaaa ttctcctctt aattccttag cagacgtatg aatagtttgt aatattggag
     3361 caattttgtc gaacttggtc ttgattgacg ttgaatcaag cgtaatcgca gattcgatat
     3421 actcatttac tttgatacca gcttcaatat caaaaagata attttttaca tctaagccta
     3481 aatcctttag tagttcaaga ttgtactttt catcttgtcg attgataagc ttttctgtcc
     3541 ctttaccaaa gaatttaaca atgtattgct tatttgttgt tttggccaaa tagttttgat
     3601 tggtcattcc acccagttgt tcaacactga ggacttcctc ttcttgacta agtaaggaag
     3661 aaattttttc tttaatgatt ttctccacaa ttaacctcca gtacttatac ttcccactta
     3721 aacactgttt taaaggctgt gtttaaatcg gttgcaaaga cacgatgaat atctttaatt
     3781 tctcttacag gttcttctag ataaaggata tttttaagac gattggcaaa tttcttgact
     3841 tccatcattt ggatagcatt tttaaaatca atgcgaccag aacgagatga cccaaccaaa
     3901 atcaagccct tttctaaggc atcgcgagta ttgagattga ctttatattc gctaactccc
     3961 atcatgagaa tcgttccctg aggacgaatg tagcgaatca agtcattaat agctggtcca
     4021 gtaccatcac caccacaaca ttcaaaagca tggtcaaagg ccaactcttc aggaatatta
     4081 tccgtaatat agcattcttt ggcaaatgag aagagttcca acttttccca atgacgacca
     4141 ataaccacaa tctctgattc tggcaaagta tagttgataa tattggcaac cacaaaagct
     4201 aaacttccat ctccaataac ggcgatccgc gaccgcttgc tatgagcaag agtcaataga
     4261 cgattcatag cgtgcatgcc cacactgaca aactctgtaa tggctgcaac cgtatcttca
     4321 atagcatcat aagccaccac acgatcttta gggagagaaa caaactctct cataaagcca
     4381 tcaaatccac tagacaagaa atgggtccct gtcatgtagt tttcatagaa ttcttcatca
     4441 ctctgcatag gagactgatt gggaatcatg acaacttttt gaccaacctc gtaggttccg
     4501 gtcgggtcag aaatgacggt tccacatgac tcgtgaatca ttgccattgg aagcttttta
     4561 ttcaaaatct tgggatcacg ttttccctga tagtaacgct gatccgcatg acagacagcc
     4621 atgtagttgg gacggataag gatatgattc tcttggtcaa tagcctcttc ctgatatttg
     4681 acattgataa acttaggctt agttagttga taaatttgat taatcatttt actagtcttt
     4741 ctcaatcata ctttttgcaa tcttcaaatc tgttacggtt gtaatcttca gatttgagta
     4801 ttcacctttg gccaaggcca catcttttcc tttgatcaca aagattttac atgcatctgt
     4861 caagatttcc ttctcttcat cagaaagaga tccataaagg tccacgaagt ccttgcaacg
     4921 gaatgtttga ggtgtttgtc cttgataaag gtgagcacga tttggaatat ctgtaataaa
     4981 ttgaccattg gtactttcaa cgatagtatc aactgcttct accactgtgt ccactgcgtc
     5041 atgattttgg gcaagttgga tattgtcctg aatcatgcga agtgtaataa atggacgaac
     5101 agaatcgtgg gtaacaacga tatcctctgg agtaagcgga cgataagcat caatggcttc
     5161 aatgattttc ttaatacttg tattgcggtc agcaccaccc tttgtaatga tgatacgttc
     5221 cttataaaga ggaagatatt tatctacaag atcttctgca tgagaaaccc agtctccatg
     5281 aacaccaact acaatttttt caatacttgg ctccaagaca aatttttcaa ttgtatgaat
     5341 caaaataggt cgatcaccta gctctaaaaa ttgttttggc aagttactga tccccatgcg
     5401 tgtgccagtt ccaccggcaa gaattcctgc ataaatcatc tattttctcc tttgtcttac
     5461 taaaaaaact tattctctct attataccac aatctagtcc tatcataaaa gaaatactgg
     5521 tcctcccctt ctagaatagg agaattatgc agttctatta ttcaaagaaa ctagtccatt
     5581 tctagtaatg actaggaatt ctgtagcaat tactaataaa tggctgcgaa attttagagt
     5641 ccttcagaat aatatacttt ccttaaagaa aacttaaaac ttaagatttg aaacttcaaa
     5701 gtgattactt gacttactgc ccttcatttc ttattagcta actttatgat ataatgaaaa
     5761 acgaggtaaa ttgaatgaaa agtataaaat taaatgctct atcttacatg ggaattcgtg
     5821 tcttgaatat tatttttccc atcctaactg gaacctatgt cgcgcgtgtc ttggaccgaa
     5881 ctgactatgg ttacttcaac tcagtcgaca ctattttgtc atttttcttg ccctttgcaa
     5941 cttatggtgt ctataactac ggtttaaggg ctatcagtaa tgtcaaggat aacaaaaaag
     6001 atcttaacag aaccttttct agtctttttt atttgtgcat cgcttgtacg attttgacca
     6061 ctgctgtcta tatcctagcc tatcctctct tctttattga taatccaatc gtcaaaaagg
     6121 tctaccttgt tatggggatt caactcattg cccagatttt ttcaatcgaa tgggtcaatg
     6181 aagctctgga aaattacagt tttctctttt acaaaactgc cttcatccgt atcctgatgc
     6241 tggtctctat tttcttattt gttaaaaatg aacacgatat tgttgtctat acacttgtga
     6301 tgagtttatc gacgctgatt aactacctga ttagttattt ttggattaaa agagacatca
     6361 aacttgttaa gattcaccta agtgatttta aaccactctt tctccctctg acagccatgt
     6421 tagtctttgc caatgccaat atgctcttca cttttttaga tcgcctcttc ctcgttaaaa
     6481 cagggattga tgtcaacgtt agttactata ccatagctca gcgaattgtg accgttatag
     6541 ctggggttgt aacaggtgca attggagtga gtgtgcctcg tctcagttac tatctgggga
     6601 aaggagacaa agaagcctat gtttctctgg ttaatagagg tagtcgaatc tttaacttct
     6661 ttatcattcc actgagtttt ggactcatgg ttttaggacc aaatgccatc ctactttacg
     6721 gtagtgaaaa atatatcgga ggcggcatct tgacctctct cttcgctttt cgtacgatta
     6781 tcctggcctt agataccatt cttggttccc aaattctctt taccaatggc tatgaaaaac
     6841 gtatcacagt ctatacagtc tttgctgggc tactcaattt gggcttgaat agtctcctct
     6901 ttttcaacca tatcgtggct cctgaatact acttactgac aactatgtta tcagagactt
     6961 ctctacttgt tttctatatc attttcatcc atagaaaaca actcatccac ttgggacata
     7021 tctttagcta tactgttcga tactctctct tttcactttc ctttgtagca atttatttcc
     7081 tgattaattt cgtgtatcct gtggatatgg tcattaattt gccatttttg attaatactg
     7141 gtttgattgt cttgctatca gctatctctt atattagtct acttgtcttc acaaaagata
     7201 gcattttcta tgaattttta aaccatgtcc tagccttaaa aaataaattt aaaaaatcat
     7261 aggagtttaa aatgaaacaa ctaaccgttg aagatgccaa acaaattgaa ttagaaattt
     7321 tggattatat tgatactctc tgtaaaaagc acaatatcaa ctatattatt aactacggta
     7381 ctctgattgg ggcggttcga catgagggct ttatcccttg ggacgacgat attgatttat
     7441 ccatgcctag agaagactac caacgattta ttaacatttt tcaaaaggaa aaaagcaagt
     7501 ataagctcct atccttagaa actgataaga actactttaa caactttatc aagataaccg
     7561 acagtacgac taaaattatt gatactcgaa atacaaaaac ctatgagtct ggtatcttta
     7621 tcgatatttt ccctatagat cgctttgatg atcctaaggt cattgatact tgttataaac
     7681 tggaaagctt caaactgctg tctttcagta aacataaaaa tattgtctat aaggatagcc
     7741 ttttaaaaga ttggatacga acagccttct ggttactcct tcgaccggtt tctcctcgtt
     7801 attttgcaaa taaaatcgag aaagaaattc aaaaatatag tcgtgaaaat gggcaatata
     7861 tggcttttat cccttcaaaa tttaaggaaa aggaagtctt cccaagtggt acctttgata
     7921 aaacaatcga tttacccttt gagaatttaa gccttcctgc acctgaaaaa tttgatacta
     7981 ttttgacaca attttatgga gattatatga ccctaccacc agaagaaaaa cgcttctaca
     8041 gtcatgaatt tcacgcttat aaattggagg attaggatgc aatatttaga aaaaaaagaa
     8101 attaaagaaa ttcaactagc cctgctggac tatattgatg agacttgtaa gaaatatgat
     8161 attccttatt ttctcagtta tggaaccatg cttggagcca tccgccacaa aggtatgatt
     8221 ccttgggatg atgatattga tatttccctt tatcgtgagg attatgagcg tttactgaag
     8281 attattgaag aagaaaatca ccctcgctac aaggttcttt cctacgatac atcttcttgg
     8341 tacttccata atttcgcatc gattttggac acttctactg ttatagaaga ccatgttaag
     8401 tacaagcgtc atgataccag ccttttcatc gatgtcttcc caattgatcg atttacagac
     8461 ttgagcattg tcgacaagag ctataagtat gtggctcttc gtcaactagc ttatatcaaa
     8521 aaatcacgag cagttcacgg tgatagcaaa ctaaaagatt ttcttagatt atgtagctgg
     8581 tacgctctcc gatttgtcaa tcctcgctac ttttacaaga aaattgatca actagtcaaa
     8641 aatgctgtaa ccaacactcc tcaatatgaa ggaggagttg ggatcggtaa ggaagggatg
     8701 aaagaaatct tcccagttga tacctttaaa gaactgattt taactgagtt tgagggccgt
     8761 atgttgcctg ttcccaaaaa atatgaccaa tttttaaccc agatgtatgg cgattatatg
     8821 acaccaccat caaaagaaat gcaagagtgg tatagtcata gcattaaagc ttatcgcaaa
     8881 aactgattga ggggtattat acaaactact aagatagagg ttattcaaaa acataatttt
     8941 agtagaaaat gaaata
//
LOCUS       DAVLMQ010000066         8564 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000066 DAVLMQ010000000
VERSION     DAVLMQ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8564
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.066"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            59..493
                     /locus_tag="VXF95_001892"
     CDS             59..493
                     /locus_tag="VXF95_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HEV1082393.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVVAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            505..1695
                     /locus_tag="VXF95_001893"
     CDS             505..1695
                     /locus_tag="VXF95_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HEV1082394.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREATLKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSAQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEHYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            1706..2197
                     /locus_tag="VXF95_001894"
     CDS             1706..2197
                     /locus_tag="VXF95_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HEV1082395.1"
                     /translation="MTMPNIVMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKNVKDALTLVEGGVPIKE
                     INIGNIHNATGKEQVTRSIFLGEEDKVALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            2212..2991
                     /locus_tag="VXF95_001895"
     CDS             2212..2991
                     /locus_tag="VXF95_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HEV1082396.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFVFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            2978..3796
                     /locus_tag="VXF95_001896"
     CDS             2978..3796
                     /locus_tag="VXF95_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HEV1082397.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPTKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            3796..4089
                     /gene="yajC"
                     /locus_tag="VXF95_001897"
     CDS             3796..4089
                     /gene="yajC"
                     /locus_tag="VXF95_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HEV1082398.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIQDDLVSLQIAKGVVIHVEKESVMGKTKELLFK"
     gene            4111..6012
                     /locus_tag="VXF95_001898"
     CDS             4111..6012
                     /locus_tag="VXF95_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HEV1082399.1"
                     /translation="MKEERRQFFERIDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWAYMLNRQEYLLQFMIGYVVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSHYRAKYTLSNWGILQTIPMLAIYHFFADKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     KRAWQPRSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALTQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSNKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDICVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            6072..7073
                     /locus_tag="VXF95_001899"
     CDS             6072..7073
                     /locus_tag="VXF95_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HEV1082400.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(7183..7518)
                     /locus_tag="VXF95_001900"
     CDS             complement(7183..7518)
                     /locus_tag="VXF95_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082401.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLTNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(7529..7771)
                     /locus_tag="VXF95_001901"
     CDS             complement(7529..7771)
                     /locus_tag="VXF95_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082402.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTIIFFIIPPIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(7781..8323)
                     /locus_tag="VXF95_001902"
     CDS             complement(7781..8323)
                     /locus_tag="VXF95_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HEV1082403.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIVLFYLM
                     IFGNLIPLLLAYKYPQEVALIYPPLILVIALIAAGYVTYQMKKAGITAIDPDMLSEKE
                     SKQLHYPGLKAGLFFGLWMFFITPLLGILIGEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKDPDED"
     gene            complement(8339..8533)
                     /locus_tag="VXF95_001903"
     CDS             complement(8339..8533)
                     /locus_tag="VXF95_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082404.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
BASE COUNT         2628 a         1481 c         1920 g         2535 t
ORIGIN      
        1 aggattacaa tggggaatat aaagtaaacc ggtaaaccta aacaagaaag gagaaaagat
       61 gaaaattgta cttgtagggc atggacattt tgctacaggg atttatagtt ctttacaatt
      121 gattgcaggt aatcaagaaa atgtggaggc gattgacttt gtggaaggaa tgtcagcaga
      181 tgaactcaag caaaaaatct tacttgcaat ttcaaatgaa gaagaagttt taatcctaag
      241 tgatctcttg ggaggatcgc cattcaaggt ttcttctacc ataatgggag aaaatccagc
      301 caaaacaatg aatgttctct cgggtttgaa cttagccatg ttaatggaag cagtctttgc
      361 tagaatggct catagctttg atgaggttgt taataaatca gtagtggtgg cccagggcgg
      421 agtcgtaaat ggtaaagaat tgttttcaac ggatgcagag gaagaggaag aagatttcga
      481 atcgggtatt taaagggtaa aagaatgata aaaaaggtta cgattgaaaa aataaaatcg
      541 cctgagcgct tcttagaagt accacttctg acgaaagaag aagtcggcca ggcaatcgat
      601 aaggttattc ggcagttaga actcaacctt gactatttca aggaagattt cccgacacca
      661 gctacctttg ataatgtcta tccaatcatg gataacacgg aatggaccaa tggtttctgg
      721 acaggagaac tgtggttggc ttatgaatac agtcaacagg atgcatttaa aaacatcgct
      781 cataaaaatg ttctttcttt cctggatcgt gtcaataaga gagtagaatt ggatcaccat
      841 gatctcggct tcttgtacac accgtcttgt atggctgaat ataagataaa tggagatgga
      901 gaggctagag aagcaacctt gaaagctgca gataagttga ttgaacgcta tcaagaaaaa
      961 ggtggtttta ttcaagcttg gggagacttg ggcaagaaag agcattaccg tttgattatc
     1021 gactgcttgc tcaatatcca actcttattc tttgcttatc aagaaacagg cgatcaaaaa
     1081 tactacgata ttgcagaaag tcatttctat gcttcagcta ataatgtaat ccgtgatgac
     1141 gcttcgtcct tccacacctt ctattttgat cctgagacag gtcaaccctt taaaggtgta
     1201 acgagacaag ggtatagtga tgattcatgc tgggcacgtg gtcaatcatg gggagtctat
     1261 ggtattcctt tgacttatcg tcacttaaaa gacgagtcct gctttgactt gtttaagggt
     1321 gtgaccaatt atttcttgaa tcgtctgcca aaagatcatg tgtcctattg ggatttgatt
     1381 tttaatgatg gtagtgctca atcacgagat tcttcagcaa cagctatcgc cgtctgtggg
     1441 attcatgaaa tgctaaaaca tctcccagag gtggatgctg acaaagatat ttataaacat
     1501 gctatgcatg ccatgcttcg ttccttgatc gaacattatg caaatgatca atttacccct
     1561 ggtgggacaa gtctcctcca cggtgtgtac tcatggcatt caggtaaagg agtggatgaa
     1621 ggcaatatct ggggtgacta ctattaccta gaagccctta tccgtttcta caaagactgg
     1681 aacctatatt ggtaggagga gaaatatgac aatgccaaat attgttatga cccgtatcga
     1741 tgaacggttg attcatggac aaggacaact ttgggtaaaa tacctaggtt gtaatacggt
     1801 cattgttgcc aatgacgaag taagcacgga caagatgcaa caaactctga tgaaaacagt
     1861 tgtgccagac tcagttgcca tgcgtttctt ccctttgcaa aaggtgattg atatcattca
     1921 caaggctaat cctgctcaaa cgatctttat cgttgtaaag aatgtgaagg atgctttaac
     1981 cttggtagaa ggtggtgtcc ctatcaaaga aatcaatatt gggaacattc acaatgctac
     2041 tggtaaagag caagtgacac gctccatctt cctgggtgaa gaggacaagg tggccctcaa
     2101 ggaattgagc caaactcatc aagtaacatt taatacgaaa acaactccaa caggaaatga
     2161 tggagctgtt caagtcaaca ttatggacta tatttaaaag aggagatcgt tatgtcgatt
     2221 aatgtatttc aagcgatttt aattggatta tggacagctt tctgttttag tggaatgctg
     2281 ttaggaattt acaccaatag atgtattgtt ctgtcatttg gtgtcggaat tattctaggt
     2341 gatctgccta ctgctcttgc aatgggagct attggtgaat tggcttatat gggattcggt
     2401 gttggtgctg gaggtactgt tccaccaaac ccaatcggac ctggtatctt tggtaccttg
     2461 atggctatca ctagtgctgg taaagtcagt ccagaagcgg ctcttgccct ctctactccg
     2521 attgctgtgg cgattcaatt cttacaaact ttcgcctaca ctgtacgtgc tggtgcgcct
     2581 gaaacggcga tgaagcactt gaaaaaccat aatttgaaga aattcaagtt cactctaaat
     2641 gcaacaattt ggttgtttgt ctttattgga tttaccttgg gttgcttggg cgccctttca
     2701 atggatacct tgttgaaact cgtagactac attccaccgg tattgcttac aggtttgaca
     2761 gttgctggta aaatgctccc agctatcggt tttgcgatga tcttgtcagt gatggctaag
     2821 aaagagttga ttccctttgt cttgttggga tatgtttgtg cagcttatct aaacatccca
     2881 acaattggta ttgcaattgt aggtactatc tttgctttga ttgaatttta taacaagcca
     2941 aaaacagcgg atcatgtggt agaggaggaa gcacacgatg actggatcta acaaattaac
     3001 aaaacgtgat tatcttaaaa cgtctttgcg ggcattcttt tgtcaaaatg gatttaacta
     3061 tagtaactat caagggttgg gatatgccaa tgtgatgtat cctgctttga aaaaacacta
     3121 tggagaggat caggaaggtt tctaccaagc cttggaagaa aactgtgaat tctataatac
     3181 caatccacac ttcctgcctt ttattaccag cttgcacctt gtaatgttgg aaaatggccg
     3241 accaacaaaa gaaacacgta gcatcaagat ggccttgatg ggaccattag caggtattgg
     3301 ggattctctc tctcaattct gtttagctcc attgttctca accatcgcag cttcgtttgc
     3361 tcaagaaggc ttggttgtcg gtccaatctt gttcttcctt gcgatgaata cgattttaac
     3421 agcgattaaa ttgtcaactg gtctgtatgg atacaaacta ggaacaactg tgattgataa
     3481 actaagcgaa cagatggcaa cgatttctcg tattgccaat attatcggtg taaccgtaat
     3541 tgctggtttg gcagcgacat ctgttaagat tatggtgccg attacctttg ctgcagggga
     3601 agttaaagca gacgctaaac aaagtatcgt aagtattcag ggaatgcttg ataaggttgc
     3661 tccagctctt ctaccagccc tatttacact tttagtttac tacttgatca aagaaaagaa
     3721 atggacaaca tataaactcg ttattttaac agttatcatc ggaattatcg gaagctggct
     3781 taagattata gcttaatgga tacaacattg ttttatggaa tagtgattgt cttggcagtg
     3841 agtccccttt tactgtcaag ctttcattct attcgtcagc aaaagttgct tcgcaaacag
     3901 atggagcaac gacaagagta tttagcttct ttaacatctg gtgatgaagt gttgttattg
     3961 tctggaattc atggaaaaat catttctatc caagatgact tggtctcctt gcagattgca
     4021 aaaggtgtgg tcatccatgt agaaaaggaa agtgtaatgg gaaagacaaa agaactgctt
     4081 tttaagtagt tctttttctg gtaatagata atgaaagaag aaagaagaca attttttgaa
     4141 agaatcgatg gaaaccaatg tcgtgattat atcttgtcgc actgttcaaa agactatgag
     4201 aaagtcaaga gttcccttga acgcttgatg gacaatcgtt ttatgtttga tagtccttgg
     4261 gatatggagc cttgttcaaa aatccatcaa atccaaccga tggtatggga tcaagtattt
     4321 gaagatgatc cagaatgggc ttatatgctc aatcgacaag aatatctctt gcagtttatg
     4381 atagggtatg tggtagaagg agataaggac tatattcaaa agtgcaagtt ctttctattt
     4441 gattggattg agcaggtgag agaattttct cctcaatcct tgatgactag aaccttggat
     4501 acgggtattc gttcctttac ttggttgaaa ctactcttgc tcctcttgaa atttgacttg
     4561 ctagaggaga aagaactaga gaaaattttg gtcagtctag aaaagcagat tgactttatg
     4621 aaaagccact atcgcgccaa gtacaccctt agtaactggg gaattttaca aacaattccg
     4681 atgcttgcta tctatcattt ctttgcagat aagatggacc tagaagaagc ttaccatttt
     4741 gcttcagagg agttgaaaca gcaaattgag acacagattt taggagatgg aagccagttt
     4801 gaacagtcga ttctctatca tgtagaggtt tataaagcct tgctggattt gtgtctcttg
     4861 cttccagact tgcaagatag ttaccaagag ttgctggaaa agatggcgac ctatattcaa
     4921 atgatgacag gcttagatgg acgaactttg gcttttggtg atagcgattc tacagaaacg
     4981 acagaaatgt tgagcctgtc tgctgtggtt ttgaacaagg aagaccttct taacggtctg
     5041 gatgttaaag tcgatttgct tagcctcttg ttcctggggc gagaaaaggt caagcgactg
     5101 caggaatttg aaaagagagc ttggcagcct aggtccatga tctttgaaga ctctggacat
     5161 gtctgcatta aggatgaaca tcgttatcta tttttcaaaa atggtccgct aggaagtgcc
     5221 catagccata gtgacgagaa tagtttttgc ttacagtatc aaggccaacc tattttcata
     5281 gatgctgggc gttattctta tcgggagata tatgaacgtt atctcttaaa gagtgcttgg
     5341 agtcattcga cctgcattgt agatgggaaa gctccggaaa gaatcacggg atcctgggaa
     5401 tatgaatact atcctcactc cctgttttgt caccataaag aaagggaggg agtgcattat
     5461 attgaagggg cttattggtc agcagaacct gatttgcctt atcttcacaa gagaaaaatc
     5521 ctcatgttgg tagaggatgt ctggctcttg gtagatgaca tcaggtgtca aggtcagcat
     5581 gaggcgttga ctcagtttat ccttgacaag gatgtgacct atcaagatgg gaaaatcaat
     5641 cagttgagac tatggagtga agttgatttt gatttggaag ataccatcat ttctcctaaa
     5701 tacaatgagc ttgaaagaag taacaaactc accaagcgcc aattctttga gaatcagatg
     5761 ctggattata ccatcattgc gcatgagagt tttgaaatca tccgtcattc tgtctaccag
     5821 acagatgatc gtgaagtgga aaatgctctg gcttttgaag tgaaaaatga cgaaacagac
     5881 aagctgattc tgttattaag cgaggatatt tgtgtaggtg aaaaattgtg cctcgttgac
     5941 ggaacaaaaa tgcgtggaaa atgtctagta tatgataaaa taaatgagag aatgattcgc
     6001 ttgcagtgct agaaataggc attttgaata gtgaatatgt tataataagt attagtagga
     6061 ggtgttttag attggagaag aaactgacca taaaagacat tgcggaaatg gctcagacct
     6121 cgaaaacaac cgtgtcattt tacctaaacg ggaaatatga aaaaatgtcc caagagacac
     6181 gtgaaaagat tgaaaaagtt attcatgaaa caaattacaa accgagcatt gttgcgcgta
     6241 gcttaaactc caaacgaaca aaattaatcg gtgttttgat cggtgatatt accaacagtt
     6301 tctcaaacca aattgttaag ggaattgagg atatcgccag ccagaatggc taccaggtaa
     6361 tgataggaaa tagtaattac agccaagaga gtgaggaccg gtatattgaa agcatgcttc
     6421 tcttgggagt agacggcttt attattcagc cgacctctaa tttccgaaaa tattctcgta
     6481 tcatcgatga gaaaaagaag aaaatggtct tttttgatag tcagctctat gaacaccgga
     6541 ctagctgggt taaaaccaat aactatgatg ccgtttatga catgacccag tcctgtatcg
     6601 aaaaaggtta tgagcatttt ctcttgatta cagcggatac gagtcgtttg agtactcgga
     6661 ttgagcgggc aagtggtttt gtggatgctt taacagatgc taatatgcgt cacgccagtc
     6721 taaccattga agataagcat acgaatttgg aacaaattaa agaattttta caaaaagaaa
     6781 tcgatcccga tgaaaaaact ctggtattta tccctaactg ttgggcccta cctctagtct
     6841 ttaccgttat caaagagttg aattataact tgccgcaagt tgggttgatt ggttttgaca
     6901 atacggagtg gacttgcttt tcttctccaa gtgtttcgac gctggttcag ccctcctttg
     6961 aggaaggaca acaggctaca aagattttga ttgatcagat tgaaggccgc aatcaagaag
     7021 aaaggcaaca agtcttggat tgtagtgtga attggaaaga gtcgactttc taaaatgaag
     7081 gaaaatgact tgcaatttct gttaagaaat aaaataatcc cacctagaac aagctaggtg
     7141 ggattatttg cctatgaaat gagaaattat gggagcaagc tcctaaatca actgtttttg
     7201 atctacttct ttaactactt gataaaagtt atagaagtag gccaaacttg aaatgatggt
     7261 tacgactagg aatattgaaa atttccattg gacagggttg gttaaaagtt gtggaaagga
     7321 tatgaggaga aagaagaggg ctgcgttgag gacaggtatc cgttttgatt gtattttctc
     7381 aagtccttta ttgagcgcag gaagaaagag gagtaggagt agtaaaactg tatgagaaac
     7441 agctcctgaa ataagggcaa agaaaaggaa aatactgata aaaacatgaa tgatcagtag
     7501 tctagctagt gatttcataa ggtacctcct aatcctggtc ttttttagct cttgcaatac
     7561 gaagtgagtc gacaatatgt atcatcactc cgaaaaagaa agctcccagt atagttttaa
     7621 aaatatgttt tgtatttaga agagaactga taaaatttgg attttcactt gttagggtat
     7681 caatgggtgg aattataaaa aatattattg ttccataaat cgaacctgct ttcagaccag
     7741 gataacgtaa ctgtttcttt tcttttttca tagtttcctc ctaatcctca tccggatctt
     7801 tcttagtttt tgcaatgcga cgggagatga ggaactgtat gctcgctccg aagaagatag
     7861 aaccgagaat gcttgataca ccatttctta tagtgagaag agaatgaaaa tagtcctgac
     7921 cttcacctat gagtataccg agaagaggag ttataaaaaa catccataga ccaaagaaca
     7981 aacctgcttt cagacctggg taatgtagtt gcttactttc tttctcactc agcatatctg
     8041 gatcaatagc tgtaatccct gcttttttca tttggtaggt gacatagcca gcagcgatga
     8101 gggcaatcac taaaatcaga ggaggataga ttagagccac ttcttgaggg tatttatagg
     8161 ccagaaggag tggaataaga tttccgaaaa tcatcagata aaagaggacg ataaagactt
     8221 ggttcccaat actatcggcc tcacgccgtt tgtattcgtc aaggggacca gaaataccgt
     8281 atgtgcgttt gatcagtttt tcagtaaagg tttctttttt cataagtttg ctcctttttt
     8341 aaaaatcttc ctcccaaaag agactgttga ggtcagtttg gaggctgcgg gcgagattga
     8401 gacagagttc cagagttgga ttgtacttgt cgttttcaat catattgatg gtctgtctcg
     8461 agacaccgat atccttggcg agttcgagct gggaaatacc caattccttg cgaaattctt
     8521 tcacacgatt catctggtct cctttctgaa gtgtgtcgta tata
//
LOCUS       DAVLMQ010000067         8141 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.067, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000067 DAVLMQ010000000
VERSION     DAVLMQ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8141
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.067"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..285
                     /locus_tag="VXF95_001904"
     CDS             <1..285
                     /locus_tag="VXF95_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HEV1082405.1"
                     /translation="VILAGIAVKAVKDYLVQKGGEKTIKIVEILAKNAVNAVEQVAAE
                     TGYKGDEKLAQARAKVRAELTKYNISMTDKNLDTFVESAVKQMNDVWKGR"
     gene            289..1245
                     /locus_tag="VXF95_001905"
     CDS             289..1245
                     /locus_tag="VXF95_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1082406.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTVQNEADYHWR
                     KDPELGFFSHVVGNGRVMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTDDLAGIKTHEYCTNNQPNNHSDHVDPYPYLTKWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            complement(1516..1695)
                     /locus_tag="VXF95_001906"
     CDS             complement(1516..1695)
                     /locus_tag="VXF95_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082407.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(1837..1986)
                     /locus_tag="VXF95_001907"
     CDS             complement(1837..1986)
                     /locus_tag="VXF95_001907"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082408.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            2268..2735
                     /locus_tag="VXF95_001908"
     CDS             2268..2735
                     /locus_tag="VXF95_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HEV1082409.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYDILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            2768..2864
                     /gene="ffs"
                     /locus_tag="VXF95_001909"
     ncRNA           2768..2864
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VXF95_001909"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            2921..3364
                     /locus_tag="VXF95_001910"
     CDS             2921..3364
                     /locus_tag="VXF95_001910"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HEV1082410.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            3366..3881
                     /locus_tag="VXF95_001911"
     CDS             3366..3881
                     /locus_tag="VXF95_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HEV1082411.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATSLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            3895..5256
                     /gene="radA"
                     /locus_tag="VXF95_001912"
     CDS             3895..5256
                     /gene="radA"
                     /locus_tag="VXF95_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HEV1082412.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFLIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            5329..5826
                     /locus_tag="VXF95_001913"
     CDS             5329..5826
                     /locus_tag="VXF95_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HEV1082413.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            5851..6060
                     /locus_tag="VXF95_001914"
     CDS             5851..6060
                     /locus_tag="VXF95_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082414.1"
                     /translation="MKKSSILFIFILLLCIGLQYETIYYTDGSRSGAEYGLMGVSIFL
                     ALFYMIPALYFLFRIGKNGNCQRRF"
     gene            6042..6665
                     /locus_tag="VXF95_001915"
     CDS             6042..6665
                     /locus_tag="VXF95_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HEV1082415.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIKDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            6810..7778
                     /locus_tag="VXF95_001916"
     CDS             6810..7778
                     /locus_tag="VXF95_001916"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HEV1082416.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(7912..8136)
                     /locus_tag="VXF95_001917"
                     /pseudo
     CDS             complement(7912..8136)
                     /locus_tag="VXF95_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2295 a         1434 c         1973 g         2439 t
ORIGIN      
        1 gttattttgg ctggtatcgc agtcaaggca gtcaaggact acctggttca aaaaggtgga
       61 gaaaagacca tcaaaatcgt tgaaatcttg gccaaaaatg cagtaaatgc cgtggagcag
      121 gtagctgctg aaactggcta caagggagat gaaaaactgg cacaggctcg tgctaaagtc
      181 cgtgctgagc ttacaaaata caatattagc atgactgaca aaaacttaga caccttcgta
      241 gagtcagcag tgaagcagat gaatgacgta tggaaaggac gatagggaat ggatatcgat
      301 agaaacagac tacgtacagg cttgccacag gttggggtgc agccttatcg acaagtacat
      361 gctcactcaa caggtaaccg caactcaacc gtacagaatg aagcggatta tcactggcgg
      421 aaagacccag aattaggttt tttctcgcac gttgttggga acggccgtgt catgcaagta
      481 ggtcctgtga acaacggaag ttgggatgtt gggggcggtt ggaatgctga gagttacgca
      541 gcggttgaac tgattgaaag ccattcaact aaggaagagt ttatggctga ctaccgcctc
      601 tatatcgaat tgctacgcaa tctagcggac gaagcaggct tgccgaagac tcttgataca
      661 gacgacttgg caggtatcaa gacgcatgaa tactgtacca ataaccaacc aaacaaccac
      721 tcagatcatg tggatccata cccttacttg acaaaatggg gcattagccg tgaacagttt
      781 aagcaagaca tcgaaaacgg cttgagcgct gcaacaggct ggcagaaaaa tggcactggc
      841 tactggtacg tacactcaga cggctcttat ccaaaagata agtttgagaa aatcaacggt
      901 acctggtatt atttcgatgg ctcaggctat atgctttcag accgctggaa gaagcacaca
      961 gacggtaatt ggtactactt tgaccaatca ggcgaaatgg ctacaggctg gaagaaaatc
     1021 gctgagaagt ggtactattt tgatgtagaa ggtgccatga agacaggctg ggtcaagtac
     1081 aaggacactt ggtactactt agacgctaaa gaaggcgcca tggtatcaaa tgcctttatc
     1141 cagtcagcgg acggaacagg ctggtactac ctcaaaccag acggaacact ggcagacaag
     1201 ccagagttca cagtagagcc agatggcttg attacagtta aataaaatag aaaggaaact
     1261 ttctaaattg ttctttcacc gcaggctcag gcttgcggtt tttttgtttg tctgaatcaa
     1321 gaaaacgtct aaccaaccga caccaatgtc ggtagcaaaa taaatggttt gcctaaaaaa
     1381 ttagagttaa gttctatttt tcaaaaacac gcattttgaa cgattagaaa cagaaatcta
     1441 aatcctattg ttcaaaaaaa cgtttacatg aaaaataggg aggtgttttg ttaaaaataa
     1501 aaacagtgat cgaaatcact gcttatcagt tgtagcaaat tcataaagtt tttctgctgt
     1561 gagaagtgcc attttgtcca tgcttgtttt tccttttctg aggtcagaaa cagtagtcca
     1621 tggaactcca gcaccttggg aaatagcaga tgtagacatc gaactgtcta acaattcttg
     1681 aataacttct ctcatcttat ttgtcctttt tattttttag ataaatatat acattgattg
     1741 caattataaa aatagctatt gcactaacca ttgcatttcc tctttccatt tgataaaata
     1801 gaggtgtaag gggctttcgc cccaacctct tagcgtttac ctttttcttt gacgggattt
     1861 cggtttacgc tttttgtttt gccttgcgac cgttattgcg gtcactagac ttgcgatagc
     1921 agttaccgtt tcaggaatat tgtctattgc cttttcaagt aacctgagcc aatcttcttt
     1981 gttcaacttc atcaccccct ttccttatct tgattatatt atatcacggt acaccgagaa
     2041 agtcaagcgt tttgatgaag tttttttaat tttttcaaaa aaaaaataga ccttgtccag
     2101 aggtcgggga gttggagggg acaccctcca agagtgttga tttaataaga ttttatttta
     2161 cctttttcat aataatctcc ctatagagtc accgcattcg gtggcttctt ttgtgttggg
     2221 attcatgata taataataaa atcgataagt aggaaaagag aaaagagatg tattatacgc
     2281 ttgaagaaaa agaagtcttt atgagggagg ctttgagaga ggctgagatt gctcttgaac
     2341 acgatgaaat tccaattggt tgtgtgattg tcaaagatgg ggaaatcatt ggtcgtgggc
     2401 ataatgcgcg tgaggaatta cagcgagcgg ttatgcatgc ggaaattatg gctatagagg
     2461 atgcgaactt gagtgaggag agctggcgct tgctggattg cacacttttt gtgaccattg
     2521 aaccttgtgt catgtgtagt ggggcgattg ggcttgcccg cattccaaat gtggtctatg
     2581 gggctaaaaa ccagaaattt ggcgctgctg ggagtttgta cgatatcttg acagatgagc
     2641 gtctcaatca tcgtgtggag gttgaaatag gaattttgga agatgaatgc gcagctatca
     2701 tgcaggattt ttttagaaat agacggaaaa aataattttg cttttaaaat gaataggaat
     2761 gtgatataat aaatagtgga gcaacagttc tgcgtgaagc gggtcagggg aggaatccag
     2821 cagccctaag cgatttgaat tgtgtgctct ttttttgtgc tttttccgaa taaataagat
     2881 agaataatct agaataaatg ataatagaaa agagaaaatt atgaaaattc gtggttttga
     2941 attggtttcg agttttacag atgaaaattt attgcccaag cgtgagacag cgcatgcggc
     3001 tggttacgac ttaaaggttg ctgtgcgtac agttgttgcg ccaggagaga ttgtcttggt
     3061 tccgacaggg gttaaggctt atatgcagcc gactgaggtt ctctacctct atgatcgttc
     3121 ttcaaatcct cgtaagaagg gcttggtttt aattaactca gttggggtca ttgatgggga
     3181 ttattatgga aatcctggaa atgaagggca tatttttgcg cagatgaaga atatcacaga
     3241 ccaagaggtt gttcttgaag ttggggaacg tattgtccag gctgtttttg ctactttctt
     3301 aattgcagat ggagatgcag ctgatggcgt tcgaactggt ggatttggat cgacagggca
     3361 ctagaatgaa gattatcttt gtacgtcatg gggagccaga ttaccgtgag ttagaggagc
     3421 gttcttatat aggatttggg atagatttgg cacccttgtc tgagatggga cggcagcaag
     3481 tccagaaatt gagcaaaaat cctttactct cgtcagctga aataatcgta tcttctgcag
     3541 tcacaagagc tttagaaacg gcttcgtatg tggtctgtgc tacgagtctt cctttaagag
     3601 tagagccttt attacatgaa tggcaggtct ataaaacagg aatagaaaac tttgaaacag
     3661 ctagaagact gtttttagaa aacaaggggg agttgcttcc taatagtcct attcaatatg
     3721 agacagctac ggaaatgaag tctcggtttc tagaatgtat gtctaagtat cgagaacatc
     3781 agactgtggt agttgttgct catcgaatgc tcatgcgcca gtttgtgcca aatgagaaga
     3841 ttgatttttg ccaagtgatt gagtgtgagt tagagatata gaaagaggtt tgtcatcgca
     3901 aagaaaaaag cgacatttgt atgtcaaaat tgtgggtata attcccctaa atatctggga
     3961 cgttgcccca actgtgggtc ttggtcttct tttgtggaag aggttgaggt tgccgaggtc
     4021 aagaatgcgc gtgtgtcctt gacaggtgag aaaaccaagc ccatgaaact agctgaggtg
     4081 acttccatca atgtcaatcg aaccaagacg gagatggagg aattcaaccg tgtgcttgga
     4141 ggcggagtgg taccaggaag tctcgtcctc atcggtgggg atcctgggat tgggaaatca
     4201 actcttctcc tacaagtctc aacccagttg tcccaagtgg ggacagttct ctatgtcagt
     4261 ggggaggagt ctgcccagca gattaaacta cgtgcagagc gcttaggtga tattgatagt
     4321 gagttttatc tctatgcaga gaccaatatg cagagtgttc gtgcagaagt ggagcgtatc
     4381 cagccagact ttctcattat tgattccatc cagaccatca tgtctcctga gatttcaggg
     4441 gtgcaggggt ctgtttctca ggtacgtgaa gtgaccgctg aactcatgca gttggccaag
     4501 accaataaca ttgccatctt tatcgtaggt catgtgacca aagaaggaac cttggctggg
     4561 cctcgtatgt tggagcatat ggtggatacg gtgctttact ttgaagggga gcgtcaccac
     4621 acctttcgta ttttgagagc ggtcaaaaat cgttttggtt ccactaatga gattgggatt
     4681 tttgagatgc agtcgggcgg cttggttgag gtactcaatc cgagtcaagt tttcctagaa
     4741 gagcgtttgg atggggcgac tggttcctcc atcgttgtaa ccatggaagg gacgcgtccg
     4801 attttggcgg aggttcaggc tttggtaaca ccgaccatgt ttggaaatgc caagcgtact
     4861 acgacaggac ttgattttaa ccgtgctagc ttgattatgg ctgttttgga aaaacgggca
     4921 gggcttctct tgcaaaatca ggatgcctat ctcaaatctg ctggtggtgt taaattggat
     4981 gaacctgcca ttgacttggc tgttgcagtt gctattgctt cgagctacaa agacaagcca
     5041 actaatcctc aggaatgttt tgtcggagaa ctgggcttga caggagagat tcggcgcgtg
     5101 aatcgtattg agcaacgcat caacgaagct gctaaactgg gctttactaa gatttatgta
     5161 cctaagaatt ccttgacagg aatcactctg cctaaggaaa ttcaggtcat tggcgtgaca
     5221 acgattcagg aagtcttgaa aaaggtcttt gcataatccg tgacaaattc tcttaaaaat
     5281 gataagatag gagaaatatt tgactatcaa attttcaagg agggaatcgt gtcgtatttt
     5341 gaacagttta tgcaagccaa tcaggcttat gttgccctac atgggcagtt aaatttgcca
     5401 cttaaaccta aaaccagagt agccattgtg acctgtatgg actcacgttt gcacgttgcg
     5461 caagctctag gtttggcact tggggatgct catatcttgc ggaatgcagg tggtcgagtg
     5521 actgaagaca tgattcgttc gctagttatt tcccagcaac aaatggggac aagagagatt
     5581 gtggtattgc accatacaga ctgtggtgct cagacctttg aaaatgaacc ttttcaggag
     5641 tatttaaaag aggaattagg tgtagatgtg tcagaccagg acttcttgcc cttccaagat
     5701 atagaagaga gtgtacgcga ggatatgcaa ctgcttatcg agtctcccct aataccagac
     5761 gatgtcatta tctctggtgc catttacaat gttgatacag gaagtatgac agtcgtagaa
     5821 ttataaatac ttcatttaga aagaaagtgt atgaagaaaa gcagtatttt atttattttt
     5881 attttattgc tatgtattgg tttacagtat gaaaccatct actatacgga cggttcgagg
     5941 tcaggtgcgg aatatggact aatgggagtt tctatctttc tagctctctt ttacatgatt
     6001 ccggctcttt attttctctt ccgtattggg aaaaatggga attgccaaag aaggttttga
     6061 ttctgtcttt attgggaggg atgttccttt caggctggtt gtctagtttt gctaatactt
     6121 atatccatga tttactgggg gttcttttcc cagatagtac atttttaaat gcctttgaaa
     6181 gtgctattgt ggctcctttg gtagaagaac ccttgaaatt attgccactt gtttttgttt
     6241 tggctttgat tcctgtgcga aaattaaaat ctttgttttt acttggaatt gcttccggtt
     6301 tgggattcca aatgattaag gatattggtt atattcgtac ggatttgcca gagggctttg
     6361 attttactat ttcgcgaatt ttagagcgta tcatctcagg aattgcctct cactggactt
     6421 tttcaggtct agctgtagta ggtgtttact tgctttacag agcctataaa ggacagaagg
     6481 ttggcaagaa acagggcctt atttttctag gtttagcctt gggaactcac ttcttgttta
     6541 actctccttt tgtggagttg gaaacagagt tgcctttagc gattccagtg gttacggcta
     6601 ttgctctcta tggtttttat catgcttatt gctttgttga gaaacacaat gagttgatga
     6661 cctagaatat ttttcaaaag aatgatgcaa gggtacaaat atggtgccct tcttttattt
     6721 ttgattgaaa aatagtgcaa aaagcgctac aatggtagat ggaaaatctt gtgaaaagca
     6781 caagttatac atatataccg gaggaaatca tgtctttttc tgatttaaag ctgtttgccc
     6841 tttcttctaa taaagaattg gcagaacgtg tggcgcagga gattgggata gagttgggga
     6901 aatcaagtgt tcgccaattt tcagatggag agattcaggt caacattgaa gaatcaatcc
     6961 gtgggaaaca cgtctttatc ctacaatcaa ctagttcgcc tgtaaatgac aatctgcttg
     7021 aaattttgat tatggtagat gctttgaagc gtgcgagtgc agaatctgtc aatgttgtca
     7081 tgccttacta tgggtatgca cgtcaggata gaaaggcgag agcgcgtgag ccaatcactt
     7141 caaaacttgt cgcaaatatg cttgaagtag ctggagtgga tcgtttattg accatcgact
     7201 tgcatgctgc gcaaattcaa ggattctttg atattcctgt ggatcatttg atgggtgctc
     7261 ctctgattgc agattatttt gagcgtcgtg gtatggttgg ttctgactat gtggttgtca
     7321 gcccggacca tggaggggtg actcgtgctc gtaagttggc agaatttttg aaaacatcta
     7381 tcgctattat tgataaacgt cgtagcgttg ataagatgaa tactagtgaa gttatgaaca
     7441 tcatcggtaa ggttgaaggc aagacttgta tcttgattga tgatatgatt gataccgctg
     7501 gaacgatttg tcatgcggca gatgctcttg cggaagctgg tgctgttgaa gtctatgcaa
     7561 gctgtacgca cccagttctt tctggtcctg ctacggacaa tatccaaaaa tcagctatta
     7621 agaaattggt tgttttggat accatctatc ttccagaaga gcgtttgatt gataagattg
     7681 agcagatttc aatcgctcat ctcctagggg atgctatcgt acgtattcat gaaaaacgac
     7741 cactttctcc acttttcgat attgagaaaa aaatttaatg accaagcctg agatgattct
     7801 caggtttttt cgtctttttt ccgaataaat agatagtagc ggtgaatcta gtaaagctag
     7861 atttaaaact gtgatataat aaaaagagaa gaaatatgac tgtacgtcat cagaagtttc
     7921 agcgaccatc atttttgaac agtgatagca cttgaatcga cgctttctaa ggagaattct
     7981 agtaggtata ccagtcgttt caagataagg aattttagaa ggtttttgaa agtcatattt
     8041 cttcaattgg tttccgcact cagggcaaga tggggcgtcg tagtccagtt tggcgatgat
     8101 ttccttgtgt gtatccttat tgatgatgtt taaaatctgg a
//
LOCUS       DAVLMQ010000068         7973 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000068 DAVLMQ010000000
VERSION     DAVLMQ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.068"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            42..989
                     /locus_tag="VXF95_001918"
     CDS             42..989
                     /locus_tag="VXF95_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HEV1082417.1"
                     /translation="MTEEKFQKIIQSKDTETLAFILESTPYHLSIDILEDPSQTEISL
                     MTKLVNDYRWAYAESPSDIIVTLFALRYVYHNIKVLLKSKAAIKKDFSKLLIPIGIFD
                     IESLKHLVSSLHSDTLPDFMVREVESIWNEYETFNNIRVLDVGADLAYFKHLKLLSNE
                     LDEVLSQVIVEMIDFYNIITVKRGLSQNKSHGDILQLLSDEGSISAKEFIYIVENQEI
                     FVWFNKINPSLDSIFSTYELKMQDATISSSELEFLCDLLLYKTLDQGRYNVEGPLVLA
                     RYLLGCEFEVKNLRMIISALQNTIPFESIKERIRPHYGS"
     gene            979..1299
                     /locus_tag="VXF95_001919"
     CDS             979..1299
                     /locus_tag="VXF95_001919"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HEV1082418.1"
                     /translation="MEANKYKIGIIGSRDIILPFSMIGFDIFPAYQEQEAINTLRKLA
                     QSDYGVIYITEDIASMILDTIRHYDSQVVPAIILLPTHKQGLNLGLKRIEDNVEKAVG
                     HNIL"
     gene            1362..3137
                     /locus_tag="VXF95_001920"
     CDS             1362..3137
                     /locus_tag="VXF95_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HEV1082419.1"
                     /translation="MTQGKIIKVSGPLVIASGMQEANIQDICRVGKLGLIGEIIEMRR
                     DQASIQVYEETSGLGPGEPVVTTGEPLSVELGPGLISQMFDGIQRPLDRFKLATHNDF
                     LVRGVEVPSLDRDIKWHFDSTISIGQKVSTGDILGTVKETEVVNHKIMVPYGISGEVV
                     SIASGDFTIDEVVYEIKKLDGSFYKGTLMQKWPVRKARPVSKRLIPEEPLITGQRVID
                     TFFPVTKGGAAAVPGPFGAGKTVVQHQVAKFANVDIVIYVGCGERGNEMTDVLNEFPE
                     LIDPNTGQSIMQRTVLIANTSNMPVAAREASIYTGITMAEYFRDMGYSVAIMADSTSR
                     WAEALREMSGRLEEMPGDEGYPAYLGSRIAEYYERAGRSQALGLPEREGTITAIGAVS
                     PPGGDISEPVTQNTLRIVKVFWGLDAPLAQRRHFPAINWLTSYSLYKDSVGTYIDDKE
                     KTDWNSKITRAMNYLQRESSLEEIVRLVGIDSLSENERLTMEIAKQIREDYLQQNAFD
                     SVDTFTSFAKQEAMLSNILTFADQANHALELGSYFTEIIEGTVAVRDRMARSKYVSED
                     RLDEIKIISNEITHQIQLILETGGL"
     gene            3138..4523
                     /locus_tag="VXF95_001921"
     CDS             3138..4523
                     /locus_tag="VXF95_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000111247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HEV1082420.1"
                     /translation="MSVIKEYRTASEVVGPLMIVEQVNNVSYNELVEIQLHNGEIRRG
                     QVLEIHEDKAMVQLFEGSSGINLEKSKIRFAGHALELAVSEDMVGRIFNGMGKPIDGG
                     PDLIPEKYLDIDGQAINPVSRDYPDEFIQTGISSIDHLNTLVRGQKLPVFSGSGLPHN
                     ELAAQIARQATVLNSDENFAVVFAAMGITFEEAEFFMEELRKTGAIDRSVLFMNLAND
                     PAIERIATPRIALTAAEYLAFEKDMHVLVIMTDMTNYCEALREVSAARREVPGRRGYP
                     GYLYTNLSTLYERAGRLVGKKGSVTQIPILTMPEDDITHPIPDLTGYITEGQIILSHE
                     LYNQGYRPPINVLPSLSRLKDKGSGEGKTRGDHAPTMNQLFAAYAQGKKVEELAVVLG
                     ESALSDVDKLYVKFTKRFEEEYINQGFYKNRNIEDTLNLGWELLSILPRTELKRIKDD
                     LLDKYLPLVEV"
     gene            4546..5157
                     /locus_tag="VXF95_001922"
     CDS             4546..5157
                     /locus_tag="VXF95_001922"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HEV1082421.1"
                     /translation="MVRLNVKPTRMELNNLKERLKTAERGHKLLKDKRDELMRRFISL
                     IRENNQLRKEVESYLIDNLKAFAVAKSLKNSLMVEELFSIPSKEIELFVEKENIMSVT
                     VPRMHMNITSQNENSEYSYLSSNSEMDDVFATMNSLIDKLLRLAEVEKTCQLMADEIE
                     KTRRRVNGLEYSIIPNLSETIHYIELKLEEAERANLVRIMKVK"
     gene            5233..5436
                     /locus_tag="VXF95_001923"
     CDS             5233..5436
                     /locus_tag="VXF95_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000218559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082422.1"
                     /translation="MTVSGYLFQNFGLLDNENVSTDLDLGLISRKCNFKEKDKLKKDV
                     LARVGLTHIHLEQKIYELSGGEA"
     gene            5533..5643
                     /locus_tag="VXF95_001924"
     CDS             5533..5643
                     /locus_tag="VXF95_001924"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082423.1"
                     /translation="MKLLLDMKNENRLIIIATHNPDIWNQADEVINLNQL"
     gene            complement(5743..7094)
                     /locus_tag="VXF95_001925"
     CDS             complement(join(5743..6653,6653..7094))
                     /locus_tag="VXF95_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISSpn4 family transposase"
                     /protein_id="HEV1082424.1"
                     /translation="MKLSYEDKVQIYELRKQGYSLEKISNKFEINNSNLRYMIKLIDR
                     YGIEFIKKGKNRYYSPELKQEMIDKVLHENWSQDRVSLKYALPNRGMLPNWLAQYKKN
                     GYTIVEKTRERVPKMGRKRKKTWEEMTELERLQEENERLRTEVAYFKKVKRAGRQGRS
                     PRARKAEIVREMASGGFQLDLLLETARLARSTYYYQLKGLGGLDKDKDLKAEIQAIFT
                     EHKGNYGYRRVTLELRNRGFVVNHKKVQRLMKVLGLTARIRRKRKYSSYQGEIGKKAE
                     NLIQRQFEASRPMEKCYTDVTEFAIPASSQKLYLSPVLDGFNSEIIAYNLSTSPNLEQ
                     GKAMLNQAFTEKHYENTILHSDQGWQYQHDSYHRFLESKGIQASMSRKGNSPDNGMME
                     SFFGILKSEMFYGYEKTFQSLNQLEQAIVDYIDYYNNKRIKIKLKGLSPVQYRTKSFG
                     "
     gene            7679..7897
                     /locus_tag="VXF95_001926"
                     /pseudo
     CDS             7679..7897
                     /locus_tag="VXF95_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         2581 a         1247 c         1548 g         2597 t
ORIGIN      
        1 caaaaataaa tacgacgatt tcggtaaaag aaaacgattt tattacagaa gaaaaatttc
       61 aaaaaattat acaatccaaa gatacggaga cattggcatt tatcttagaa tcaactccct
      121 atcatttatc gattgacatc ttagaagatc ctagtcagac agagatttcg ctaatgacaa
      181 aattagtcaa tgattataga tgggcctatg ctgaaagtcc gtctgatata attgtgactt
      241 tatttgcttt acgatatgtt tatcataata tcaaagtttt attaaaatct aaggcggcaa
      301 ttaagaaaga tttttctaaa ttattaattc caatagggat ttttgatata gaaagtttaa
      361 aacatttagt ttcttcctta cattcagata cacttcctga ttttatggtt cgtgaagtag
      421 aatcaatttg gaatgagtat gaaactttta ataatattcg tgtacttgat gtcggagctg
      481 atctagcata ttttaaacat ctgaaacttt tatctaatga gttagatgag gtactgtctc
      541 aggttattgt cgaaatgatt gacttttata atattattac tgtaaaacgt ggtttatctc
      601 aaaataagag tcatggggat attttacaat tactttcaga tgaaggaagt atttctgcta
      661 aagaatttat atacattgta gaaaatcaag aaatatttgt gtggttcaat aaaataaatc
      721 caagcttaga ttcaatcttt tcaacttatg aattgaagat gcaggacgca acaatttcat
      781 cttctgagtt agaattttta tgtgatttac tattgtataa aactttagat caaggaaggt
      841 acaatgtaga ggggccgtta gttcttgcta gatatttatt gggatgtgag tttgaagtaa
      901 agaatctcag aatgatcata tcagctcttc aaaatacaat tccctttgaa tcaataaaag
      961 aaaggatacg cccacattat ggaagctaat aagtataaaa ttggcataat tggtagccgt
     1021 gatattattt taccatttag catgattggg tttgatatat ttcctgccta ccaagaacaa
     1081 gaagctataa atacactaag aaaattagct caatctgatt atggtgtcat ttatatcact
     1141 gaagacattg cttcaatgat attagataca attcgccatt atgattccca agttgtgcct
     1201 gctattattt tattaccgac tcataaacaa ggtttaaatt taggattaaa acgtatagag
     1261 gataatgtag agaaagcagt aggacacaat attttataat aatgtacaaa attgtctgta
     1321 atattattct ataatttttg gacttagtaa ggagaataac tttgactcaa gggaagatta
     1381 taaaagtatc gggacctcta gttattgcat caggtatgca ggaggctaat attcaagata
     1441 tttgccgtgt aggtaagcta gggttaatcg gtgaaattat tgaaatgaga agagatcagg
     1501 catctatcca agtctatgaa gaaacatctg gtcttggtcc gggagaacct gttgttacaa
     1561 ctggagaacc tctctcggtt gaattagggc ctggattgat ttctcaaatg tttgatggca
     1621 tacaacgccc attagatcga tttaaattgg ctactcataa tgattttcta gttcgtgggg
     1681 tagaagttcc aagtttggat agagatatta agtggcattt tgattccact atatcaattg
     1741 gtcaaaaagt gagtacgggt gatattcttg gaactgtcaa ggaaaccgaa gtagttaatc
     1801 ataaaattat ggttccttat ggaatatctg gcgaagtcgt ttctattgcc tctggcgatt
     1861 ttacaattga tgaagttgta tatgaaataa aaaaattgga cggtagtttc tataaaggaa
     1921 cacttatgca aaaatggcct gtccgcaagg cgcgtcctgt ttctaaacgt ttaatcccag
     1981 aagaaccatt aatcacaggt caacgagtta ttgatacatt ctttccagta accaaagggg
     2041 gagcagcagc tgttcctgga ccgtttggag caggaaagac agttgtacaa caccaagtag
     2101 ctaaatttgc caatgttgat attgttattt atgtcggttg tggagaacgt ggaaatgaaa
     2161 tgacggatgt actgaatgag tttcctgagt tgattgaccc taatacagga caatcaatta
     2221 tgcaacggac agttctgatt gctaatactt caaatatgcc tgttgctgct cgtgaggctt
     2281 caatttatac aggaattacc atggctgagt attttcgtga tatgggctac tctgtcgcca
     2341 ttatggctga ttcgacttca cgttgggcag aagcgctacg tgaaatgtca ggacgtctag
     2401 aagaaatgcc tggtgatgag ggttatcctg cttatcttgg aagtcgtatc gctgaatatt
     2461 atgaaagagc gggacgttct caggctctag ggcttccaga acgtgaagga acgattactg
     2521 ctattggagc tgtatcgcca cccggtggag atatttcaga accagttact caaaacactt
     2581 tacggattgt gaaagttttt tgggggcttg atgctccgtt ggcacagcga cgtcattttc
     2641 ctgcaattaa ctggcttacc tcttattcac tctataaaga cagtgtggga acttatatag
     2701 atgataaaga gaagacagat tggaatagta aaataactcg tgcgatgaac tacttacaac
     2761 gggaatctag tttagaggaa attgttcgtc ttgttggaat tgattctctg tctgaaaatg
     2821 aacgactaac gatggaaatt gctaaacaaa ttagagaaga ttatttgcaa cagaacgctt
     2881 ttgattcggt agatacattc acttcgtttg caaaacaaga agcaatgtta agtaatatcc
     2941 taacttttgc tgatcaggca aatcatgctt tagagttggg ttcttacttt acagagatta
     3001 tagaaggtac cgtggcagtt cgagaccgta tggcgagaag taaatatgtt tcagaagata
     3061 gattagatga aatcaaaatt atttcaaatg agattacaca tcaaattcaa ttgatattag
     3121 aaacaggagg tctataaatg agtgttataa aagaatatag aactgctagt gaagttgttg
     3181 ggcctcttat gattgttgaa caagttaata atgtgtctta caatgagtta gttgaaattc
     3241 aacttcataa tggagaaatt cgtcgtggac aagttttaga gatccacgaa gataaagcaa
     3301 tggttcagct ttttgaagga tctagtggaa taaatttaga aaagtctaaa attcgttttg
     3361 ctggtcatgc actagaattg gctgtatctg aggatatggt tggtagaatt tttaatggga
     3421 tgggaaaacc aattgatggt ggaccagatt taattccaga gaaatattta gatattgatg
     3481 gtcaagctat taatcctgta tctagagatt atccagatga atttattcag acagggatct
     3541 cctctattga tcatttgaat actcttgtac gtggtcaaaa attaccagta ttttcaggtt
     3601 cgggcttacc tcataatgaa ttagcagctc agatagcaag acaagcgact gttttaaatt
     3661 ctgatgaaaa ttttgcggtt gtatttgcag caatgggtat tacttttgaa gaagctgagt
     3721 tctttatgga agaactcaga aaaacaggag cgatcgatcg ttcagtctta tttatgaact
     3781 tggcaaatga tcctgcaatt gagcgtattg caactccccg cattgcttta actgcggcag
     3841 agtatctagc ttttgaaaaa gatatgcatg ttctagttat catgacggat atgactaact
     3901 attgtgaagc gttacgtgaa gtctcggcag ctcgccgtga agttccaggt agacgaggct
     3961 atccgggata tttatataca aatttatcaa ctctatacga aagggctggt cgcttagttg
     4021 gtaaaaaagg ttcagtgaca cagattccta ttttaacaat gccagaagat gacataacac
     4081 atccaattcc tgatttaact ggatacatta ctgaagggca aattattttg tcgcatgagt
     4141 tgtataatca aggttatcgt ccaccaatca atgttttacc ttctctctct cgattaaaag
     4201 ataagggatc tggagaaggt aaaactcgtg gagatcatgc tccaactatg aatcaactgt
     4261 ttgcagccta tgcccaaggg aaaaaggttg aagagttagc agtagtatta ggagaatcgg
     4321 ctttatctga tgtagataaa ttgtatgtga agtttacaaa gcgttttgaa gaagagtaca
     4381 tcaaccaagg attttataaa aatcgaaata ttgaagatac gttgaatctt gggtgggaat
     4441 tactatcaat tcttcctaga acagagttaa aacgtatcaa agatgatttg cttgataaat
     4501 acttaccttt ggtagaagtt taatccagaa atggagtgat tatctatggt gcgtttgaat
     4561 gtaaaaccaa ctcgtatgga attgaataac ttaaaggaac gtttgaaaac agctgaacgt
     4621 ggacataagt tattaaagga taaaagagat gaattgatga ggcgatttat ttctttgatt
     4681 cgtgagaata atcaacttcg gaaagaagta gaaagttatc taattgataa tctaaaagcc
     4741 tttgcagttg ctaaatcatt aaagaactct ctaatggtgg aggaattatt ttcaattcca
     4801 tcgaaagaaa ttgaattatt tgttgagaaa gaaaatatca tgagtgtaac agttcctaga
     4861 atgcatatga atattacttc tcaaaatgag aacagtgaat acagctattt atcttctaat
     4921 agtgaaatgg atgatgtatt tgctacaatg aatagtttaa ttgataaatt actaagactg
     4981 gcagaagttg aaaaaacgtg tcagttaatg gctgatgaaa tagaaaaaac acgtagacgt
     5041 gtaaatggat tagaatattc gattattcca aacttgtcag aaactattca ttatatagaa
     5101 ttgaaactag aggaggcaga aagagccaat ttagttcgga ttatgaaagt gaagtagatc
     5161 ctttatttag attttaatta gatgaaccaa tatcagcttg gataaggcgg taagcctttc
     5221 taagcttttt tattgacagt atcaggatat ctttttcaaa attttggttt gttagataat
     5281 gaaaatgttt ctaccgattt agatttagga ttaataagtc gtaaatgtaa ttttaaagaa
     5341 aaagataagt taaaaaaaga tgtattagca agagttggtc taactcatat tcatctagaa
     5401 caaaagatat atgaattgtc tggcggtgaa gcataacgtg ttgctttagc gaaaatcatt
     5461 cttaaaaatc caccattaat actcgcggat gagctgactg catcactcga tccgacgact
     5521 tcacaaggaa ttatgaaatt attattagat atgaaaaatg aaaatcgtct aatcatcatt
     5581 gcaactcata atcccgatat ttggaatcaa gcagatgaag ttataaattt aaatcaatta
     5641 tagttacagc caatatatat tttctatatt ttaaagttat tttatctgaa tccgtaaaag
     5701 cagttcaatc ttgtactgac ccccaaaagt tagacaatta atttatccga aggatttagt
     5761 tctgtattgc acaggactaa gtccttttag ttttatctta attcgtttgt tgttgtaata
     5821 atcaatatag tctacaatag cttgttccaa ttgattaagc gactgaaatg tcttctcata
     5881 accataaaac atttcggatt tcaaaatgcc aaagaaggac tccatcatgc cattgtctgg
     5941 gctgtttccc ttgcgtgaca tggatgcttg aattccctta ctctctagga accgatgata
     6001 agaatcgtgt tggtattgcc agccttgatc gctatggaga atggtattct cataatgttt
     6061 ctctgtaaag gcctggttta acatagcttt cccttgttct aagtttggtg aagttgaaag
     6121 attataggcg ataatttcgc tgttaaagcc atctaaaact ggcgataaat agagcttttg
     6181 actgcttgct ggaatggcaa actctgtcac atccgtatag cacttttcca ttggtctcga
     6241 tgcttcgaac tggcgttgaa tgagattctc tgctttcttg ccaatctctc cttggtagga
     6301 ggaatacttt cgtttccgac gaattcgagc tgttaaacca agaactttca tcagacgttg
     6361 aactttctta tgattcacca caaaaccacg atttcttagt tcaagagtaa ctctacgata
     6421 gccataattt cctttgtgct cagtaaaaat agcttgaatt tcagctttaa gatctttatc
     6481 tttgtcaagc ccacctagtc ccttcaactg atagtagtaa gtcgagcgag ctaaacgtgc
     6541 tgtttcaaga agtaaatcta attgaaatcc tcctgaagcc atttctctaa ctatctctgc
     6601 ctttctcgct ctagggcttc gtccctgtct tccagctctt ttaacttttt taagtaagcc
     6661 acctcggtac gtaagcgttc attctcctct tgaagtcgct ctagttctgt catttcttcc
     6721 caagttttct tacgtttacg tcccatttta ggtactctct ctcttgtttt ctcaacaata
     6781 gtatacccgt ttttcttgta ttgcgccagc caatttggaa gcataccacg atttgggaga
     6841 gcatatttga gagaaactct atcttgagac cagttttcat gtaaaacttt atcaatcatt
     6901 tcttgtttta gttctggaga atagtatcga tttttccctt ttttgatgaa ctctattccg
     6961 taacgatcaa tcaatttaat catgtaccta agattagaat tgtttatctc aaatttattt
     7021 gaaatcttct ctaagctata tccttgcttt cttagttcat agatctgaac tttatcctca
     7081 taactcaatt tcataataaa acaccccaaa aagtagattt tttctgtcta acttttgggg
     7141 tgcagttcat cttgtactgc ttttttcttt tacgacttac gctgtttggc ttcatgagca
     7201 agccctcaaa gtgaactaat aacaaatcat gagaagtcaa agtgatgaaa tttctgtaac
     7261 agaagtagag cgaattgctg aaccattaaa tgagtatatc tcgaagtaga agcgtctatt
     7321 ttgactttta gtctgataga atggtagttt gaaaatgtaa atgatagcta ctgttcataa
     7381 aacataaaag gtaagtacgg tgttgtgaga agagctagaa attagcactt acctgattat
     7441 tccaataacc tcaaagatgt gataaaaatt tcaactactc ttatctataa taaagctacc
     7501 tgttctttga aaattgaatt cactccgtct tgattagcgt gcctgtgtaa gtagggactg
     7561 agagtatttc cctgtgaagg gcaactggca caagacgtgt gtgagaattt tctaacagac
     7621 acggagttta tcgtttccag actcaaacga tgcgacaaac tagataaagg agttaatcat
     7681 gaaggtagta aacttgtatg atttgaaaca aatgggaaat aaaggtggtt gtaccatcca
     7741 attgattcat cactttcctt ttggtatggg cttaggacat ctcaaaaaag actacattga
     7801 atttaaacgt gttggtatct ttgatgggaa agcagtagaa gttactcttc gagaacctta
     7861 ttcgagagat ctacttcagg ttgtcaagtc aataaagtaa ctgacaccac gagtataatt
     7921 attagaaacg tggaatctta ttaaatttta taataaatat attaaatgaa aaa
//
LOCUS       DAVLMQ010000069         7698 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000069 DAVLMQ010000000
VERSION     DAVLMQ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7698)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7698)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7698
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.069"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..254
                     /locus_tag="VXF95_001927"
     CDS             <1..254
                     /locus_tag="VXF95_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082425.1"
                     /translation="FLGIIYDNEALRDLSKQYLNKNISELQDGSFEGGIQDAVASKQI
                     VVINEFIACLNSRCVPSQYDRFFYKDRPYIFSRKSPIKG"
     gene            436..1392
                     /locus_tag="VXF95_001928"
     CDS             436..1392
                     /locus_tag="VXF95_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001857891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082426.1"
                     /translation="MGEIGIILLLISTIFCVSPVFIKLDILGTPSHAILTFVLAIPLF
                     YILSQCLHTLLLLVSSIFCKLRPIYFYFIFVIIIGARKYYRILFHQLMGFSPGVAVFY
                     KESQTTKNLFKFYYFLYFTTLISYYFFFTFVYDKPLLLPLIPFSIIIALVQKLYRIEN
                     QQLFLLKSKVLTILESKKNCEFNLQDYHEIWKLQSKSELPCVALSYISLIKPYLSESV
                     REQIDLLEVKRFKKINHPISLYGMLDVIKLNLYLRHYNEKNKYESMLNKILEVRPDFV
                     LIEQNIDDSLNSSQPLSLSLAISEIQLLLEVYMGIKHVSIRR"
     gene            1769..2143
                     /locus_tag="VXF95_001929"
     CDS             1769..2143
                     /locus_tag="VXF95_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HEV1082427.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGFSILRWPVATAINIAFNGVLG
                     GGAISLVRNYIRNYGLGRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGD
                     AITTIWANNDVNRRDPNLNALW"
     gene            2351..3253
                     /locus_tag="VXF95_001930"
     CDS             2351..3253
                     /locus_tag="VXF95_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082428.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFVIIMLTTIFFWNIMDINHLVFNKTEFLFNQN
                     KWEKEDSFESDLTNTLKDKIQKSDLSYSDLMSLQLYDAMNQSTFLTDSELFEDILSKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIIINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            3309..3641
                     /locus_tag="VXF95_001931"
     CDS             3309..3641
                     /locus_tag="VXF95_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HEV1082429.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGGAYLSKRACQGICAALAMSPGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGKIAYCIGYGALNRGCDISGNPYPWD
                     GFISATVR"
     gene            3638..4366
                     /locus_tag="VXF95_001932"
     CDS             3638..4366
                     /locus_tag="VXF95_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082430.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFILELAIFHL
                     IRKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVANHVLTLI
                     FLIKICVDTTIKFLFIRLFDTSTLMKRRIFFLFALDVIVYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEYELFKNSK"
     gene            5502..5741
                     /locus_tag="VXF95_001933"
     CDS             5502..5741
                     /locus_tag="VXF95_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082431.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLEIFKVNFCLTDLHHLF
                     DLYKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            5726..6004
                     /locus_tag="VXF95_001934"
     CDS             5726..6004
                     /locus_tag="VXF95_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082432.1"
                     /translation="MYNDVIERISLYEFIGDIFYSKIISCCIVASDLSKNTMKLDVIF
                     FEDKNKRSAVLGLRRDKSGVFKPVTLHFTSAKKYAKVRKTDVKEMKWL"
     gene            6290..>7698
                     /locus_tag="VXF95_001935"
     CDS             6290..>7698
                     /locus_tag="VXF95_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HEV1082433.1"
                     /translation="MNKKKMILTSLASVAILGAGFVTSQPTFVRAEEAPVASQSKAEK
                     DYDAAMKNAEDAKKAVEDAQKALDDAKAAQKKYADDQKKTEEKAKKEKEASKAEQAAN
                     LKYQQELVKYIKYIRENNPKKTEAQKAMDEAEKEHKKKQAEFKKVRLEVIPSAKELEE
                     TRQKAKEAKEKEPELTKKVAEAKAKLEEAEKKVTEAKQKVDAEHAEEVAPQVKIAELE
                     NQVHKLEQKLKEIDESDSEDYVKEGLRAPLQSELDTKKAKLLKLEELSGKIEELDAEI
                     AELEVQLKDAEGNNNVEAYFKEGLEKTTAEKKAELEKAEADLKKAVDEPEKPAEESEN
                     PAPAPKPAPAPAPKPEQPAPAPAPKPEKSADQQAEEDYARRSEEEYNRLTQQQPPKAE
                     KPAPAPAPKPEQPAPAPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYYLNSNGAMA
                     TGWLQYNGSWYYLNANGAMA"
BASE COUNT         2679 a         1071 c         1419 g         2529 t
ORIGIN      
        1 gatttttggg aatcatttac gataatgaag cattaagaga tttgtcaaaa caatatttaa
       61 acaaaaatat ttcggaatta caagatggtt ctttcgaggg cggtatacaa gatgctgttg
      121 cctctaaaca aatagtagtt ataaatgaat ttatagcttg tttaaattcc agatgcgtgc
      181 catcccaata tgatagattt ttttataaag atagacctta tattttttcc agaaagagtc
      241 ctattaaggg gtgaaaattt gttacatttg gattaacaag tgtcctaggg attagaaata
      301 actctagtat agctagatat ttttgagtaa ctagaaatat cattagtcta cccatatgat
      361 tgccagaaaa gatggctgat gaatcttatt tatactgttg cagtaggcgt tgtctaggat
      421 aaataagcta tcttgatggg ggagattgga ataattttac tgcttataag cacgatattt
      481 tgtgtcagcc cagtatttat aaaattggac atcttaggaa ctccctctca tgccatctta
      541 acctttgtat tggcgatacc gttattctat attttgtctc aatgcttaca tactttgcta
      601 ttactagttt cctcaatctt ttgtaaatta agaccaattt atttttattt tatatttgtg
      661 atcattatag gagctaggaa atactatcga attctctttc accaactaat gggatttagt
      721 ccaggagtag cagtgtttta taaggagagt caaacaacta agaatctgtt taaattttac
      781 tacttcttgt actttacaac actaatttca tactattttt tctttacttt tgtgtatgac
      841 aaaccgttgc ttttgcctct tattccattt tctattatca tagcattagt acaaaaactt
      901 tatagaattg agaatcagca attatttctg ttaaaatcaa aggtactaac aatactggaa
      961 tctaagaaga attgtgagtt taatcttcag gattatcatg aaatttggaa attgcaatca
     1021 aaatctgagt tgccatgcgt ggctttatct tatatcagtt taatcaagcc atatctttca
     1081 gagagtgtgc gtgaacaaat tgatttatta gaagttaagc gatttaaaaa aataaatcat
     1141 ccaatatcac tttatggtat gttggatgtt ataaaattaa atctatattt acggcattat
     1201 aatgaaaaaa ataaatatga atcaatgtta aataaaattt tagaggtaag accagacttt
     1261 gttttaatcg agcagaatat tgatgatagt ttaaatagct cgcaaccatt atctttatct
     1321 ttagccattt cagaaatcca acttttgctt gaagtgtata tggggatcaa acatgtttca
     1381 attaggagat aaaaccagaa taatatttgc cattataggg gcaagttgca tattagtcag
     1441 tatgtatctt attccactta ttaaaactga gaataaattt tgggaaatac ttttatttat
     1501 attaggtgta ttgctaattg gaattgcgtt actaagtcaa aaaaaataaa ttttgaaata
     1561 gtattagtga gttcgcaatc atttattgct agtggtttag aactgttaag tttcaaacaa
     1621 taattgattt taaaccttag gtaacctata aaaacaaata aggtagagaa aggatatctt
     1681 atctaggtag ctaagtgata aaaacacagt cgtctatcac ttgttaggaa actatcctaa
     1741 ctatgcttaa taaaaaagga gaaaataaat ggaactcgta ttaccaaata attatgttgc
     1801 tcttgagcaa gaagagatga tgtatcttga tgggggattt tctattctga gatggcctgt
     1861 tgcaacagcc attaatatag cttttaatgg tgttttaggt ggaggagcaa tcagtctagt
     1921 tagaaattat attcgtaatt atggtttggg gcgagttaca agcgcaattg ctggagcagc
     1981 tgcaagatat gttggggtac gagttgcaaa tagagtggca ggatttgcac tgtctgctat
     2041 taatggattt gcagcttgga tgtcaattgg cgatgctatt acaacaatct gggccaacaa
     2101 tgatgtaaat aggagagacc caaatttaaa cgccttgtgg taactagata tgggtattaa
     2161 aatggaaaaa atttttgtta ttattttttt tgtatgtcta tttatatcat ccataacttt
     2221 tttagcctat gattttgtta gcgaagaaat aaaaaagttg attatttgga tgaatgtcgt
     2281 ttttttgatt ttaatcatag caatgataat ttatccaaaa ttaagaaaat gataaggaca
     2341 ctgtaaaatt atgatacgta aactaatcat ttttttatta atgctccctc tttttgtctt
     2401 gtggctagag ttgcatgtcc tagtgaataa cttactattg aatctagaat ctccccttga
     2461 ttttgtgatt agtatgagtc ttgctttctg tagtttgatt ttatcaaaaa tagttttaga
     2521 catactatac gcattgaaag atttgtacaa gaaagaagct cttattacga tttttccttt
     2581 tatttttata ggcaggaaga aagtaaatgt gaggttctcg ccctattttt cattccatcg
     2641 taaaagtttg tcgcctgatg atttaagatc taggattata tggagtttta ttcttgaaat
     2701 tgctattatc ctagtattta ttttaaaaat tccttttgtc atcattatgc ttactacaat
     2761 atttttttgg aatataatgg atatcaatca tctcgttttt aataagacgg aatttctttt
     2821 caatcaaaat aaatgggaaa aagaagattc gtttgaaagt gatttgacaa atacgttaaa
     2881 ggataaaata caaaaatcag atctcagtta ttctgactta atgtctcttc agctgtatga
     2941 tgcgatgaac caatccacct ttttaacgga tagtgaactc tttgaggata ttctgagtaa
     3001 aattgaagat tctcataaca cccttctgtg tacaggtctt gtcgagttac tgctgtatga
     3061 gatttctatt agtaacaata acaactggca agaaaaggtt gataaaatta gaatacagct
     3121 catcataata aatcaattag attttttcta ttatacaagt tggttaaggc aaaattttga
     3181 tttctgtatg aatagagagt atcataaaat gaaatctcgg aaattattac tgagtaataa
     3241 aaagatagtt taagttcatc ctatttgtaa aacaaatgaa acaatttcaa ctaaggagga
     3301 gaaaacaaat ggaacttgta ttaccaaata attatgttgt gattgatgaa gaagaaatga
     3361 tgtatcttga tgggggagct tatttaagca agcgtgcttg tcaaggaatt tgcgcagctt
     3421 tagctatgag tccaggaact tttatagcat tagctggagc tgcagtttta accaaaaaac
     3481 taataaacta tattaaagtt ggaggccttg gaggttggct tattggtgca gcagcaggaa
     3541 aaatagctta ctgtattgga tatggtgctc ttaatagagg ttgtgatatt agcgggaacc
     3601 cttatccttg ggatggattc atatctgcga cagtaagatg agtaatgtag ataagattcg
     3661 aaaaatacac attatcgtat gttggatgta tatattttta tcattcaggg cgattataaa
     3721 tgacacggag tattttttgc ttattttttt agcttttatc tactcaatag tatcactacc
     3781 tctatattct gtgaaaaata aaatagtatc tatctgtcta gccataaatt cgattctgtt
     3841 aatgagtttc cccattttaa tcaataagtt tttcccagaa agttttttga cttataccgt
     3901 attaataagt gtttttatcc tagagttagc aatctttcat ttaattagga aagattttga
     3961 tattaaattg actaacgaat ataagaaaat tagtcagttt agaagcaagg tgtctcaatc
     4021 tccttggata aaatatttag agatttctag ttttatatta actatatttc catctattct
     4081 ttatggtaca gttgctaatc atgtactgac tcttatcttt ttgataaaaa tttgtgtaga
     4141 taccacgata aaatttttat tcatcagatt atttgacaca agcactttaa tgaagaggag
     4201 aatatttttt cttttcgcat tggatgttat agtttactta tttttaggat atcttttagt
     4261 gattcaaaaa gcaggctatt tgttttcggt tttacttctt ttttctaatt tttcagttcc
     4321 atttatcaaa gaaaaggaat acgaattatt taaaaatagc aagtaataga aacataggtt
     4381 aaatcttaga acggcttaaa atcagatatg ataaagggaa atagtcttat ctaggtaact
     4441 aagtgctaca aacacaatcg aggatcactt gttaggatta cattttaatc atgcttaata
     4501 agaatggaga attcctatgg ggattgtatt actctgaagt ttcgaatacc ttagttctcg
     4561 tgattttgag ctattctagg tttagaatcc ttcagaatgt aaaattttaa gcagtcaaag
     4621 acttagaata gcctgaaaac atttattttg tagcaattct aggcttagaa ttgctcatat
     4681 atatgtattt gagctgctcg atagttagga cagctttatt ctgagaaatc tgagctatca
     4741 atgcttcaga atagtatttc gccaatggtt tttattgaag aggtgattgt tttatgatag
     4801 tctaaaataa aactgattta atggagtaaa tggagaatcg ttatatgaaa catttttttt
     4861 gcaggaattg gtgagataaa acttgttggc tacttattgt atatatgtgt aggactagcc
     4921 cctctttttc atatatatgt cataggttcg gaactgagtt ttgtgaaaat agtgttatct
     4981 attttgggag ttatatttgt aagtatgtta actattgctc gaatttatcg gacttttcta
     5041 taaagaatag tttggacttg aactgtatct aaaaacagag gttggtcgat tatcagcctc
     5101 tttcttgtcg ttgaaaagag tgagatatat tgacttttga aaaaaagatg tcataattga
     5161 gttgggataa acctaaaagt aatatagtag attgaatctg gaatagtccg ttatgactgt
     5221 taaaatattt ctagaaatta atttgacttt cctaatcgat ttgttcacat cttgtttcaa
     5281 tctactatac tttctcgtta aaccgttcgg caattcatgg tgacatggac acatagtagt
     5341 aagcacacta tgtggcttgg cagagctaaa aactgttccc ttgcgataag cctaataagc
     5401 acaacatagg gagttagaga agccgactct aatcaaccac tttgggcaat agtgagaact
     5461 gccccgtgct tttttatttt gagaaaatat ggagtttgtc gttgaaatta cttgattgta
     5521 ttttggacta tcaagaaaga ttcaatggaa aaacatgtca agtatcaacg aattataagt
     5581 atttagagat tttcaaagtg aatttttgtt tgactgattt acatcattta tttgacttat
     5641 acaaaatcac acgagattat gctagtcaaa caaaacctgc tattcaagct ggtgttttta
     5701 ttttagaaga ttttagaaat atcctatgta caatgatgta atcgaaagga tatctttata
     5761 tgagtttatc ggtgatattt tctattctaa aataataagt tgttgcatcg tagctagcga
     5821 tttatctaaa aatactatga aattggacgt catatttttt gaggataaaa ataaaagatc
     5881 cgcagtttta ggtttacgaa gagacaaaag cggagtattt aaaccagtta ctctacattt
     5941 tacaagcgct aagaaatatg ctaaagttcg taaaacagat gtgaaagaaa tgaaatggct
     6001 ataaagattg tccgcaggct taagcttgcg ttttttgttg tttaacgaaa ttaaaaaaca
     6061 agctctctca tcggaaatgt ttttatagga atgaaggaag atgatgctat gtttaaaaag
     6121 agaatcgaaa agggcaaaag tagtgtcttt atctttttgg agtagaagct tatgatatag
     6181 aaatttgtaa taaaaatgta atataaaaca tttgacaaat atttacgggg ggagtatact
     6241 taatataagt atagtctaaa aatgactatc agaaaagagg taaatttaga tgaataagaa
     6301 aaaaatgatt ttaacaagtc tagccagcgt cgctatctta ggggctggtt ttgttacgtc
     6361 tcagcctact tttgtaagag cagaagaagc tcccgtagct agtcagtcta aagctgagaa
     6421 agactatgat gcagcaatga aaaatgctga ggatgcgaaa aaagcagtag aagatgctca
     6481 aaaggcttta gatgacgcaa aagctgctca gaaaaagtat gccgatgatc aaaagaaaac
     6541 tgaggagaaa gcgaaaaaag agaaagaagc ttctaaagcg gaacaagctg caaatctaaa
     6601 atatcaacaa gagttggtta aatatattaa atatatacgt gaaaataatc caaaaaaaac
     6661 tgaagctcag aaagcaatgg atgaggctga gaaagagcat aagaaaaaac aagcagaatt
     6721 taagaaagtt agattagagg taattcctag cgcgaaagag ttagaagaga ctagacaaaa
     6781 agcaaaagaa gctaaagaaa aagaaccaga acttactaaa aaagtagcag aagctaaagc
     6841 aaaattagaa gaagctgaga aaaaagttac tgaagccaaa caaaaagtgg atgcagaaca
     6901 tgctgaagaa gtcgctcctc aagttaaaat tgctgaattg gaaaatcaag ttcataaact
     6961 agaacaaaag ctcaaagaga ttgatgagtc tgattcagaa gattatgtta aagaaggtct
     7021 ccgtgctcct cttcaatctg aattggatac caaaaaagct aaactattga aacttgaaga
     7081 gttgagtggt aagattgaag agttagacgc tgaaattgca gaacttgaag ttcaacttaa
     7141 agatgctgaa ggaaacaata atgtagaagc ctactttaaa gaaggtttag agaaaactac
     7201 tgctgagaaa aaagctgaat tagaaaaagc tgaagctgac cttaagaaag cagttgatga
     7261 gccagaaaaa ccagctgaag agtctgagaa tccagctcct gcaccaaaac cagctccagc
     7321 tcctgcacca aaaccagagc aaccagctcc agctcctgca ccaaaaccag agaagtcagc
     7381 agatcaacaa gctgaagaag actatgctcg tagatcagaa gaagaatata accgcttgac
     7441 tcaacagcaa ccgccaaaag cagaaaaacc agctccagct cctgcaccaa aaccagagca
     7501 accagctccc gcaccaaaaa cgggctggaa acaagaaaac ggtatgtggt acttctacaa
     7561 tactgatggt tcaatggcta caggttggct acaaaacaac ggttcatggt actacctcaa
     7621 cagcaatggc gctatggcta caggttggct ccaatacaac ggttcatggt attacctaaa
     7681 cgctaacggc gctatggc
//
LOCUS       DAVLMQ010000070         7600 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000070 DAVLMQ010000000
VERSION     DAVLMQ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7600
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.070"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(71..1621)
                     /locus_tag="VXF95_001936"
     CDS             complement(71..1621)
                     /locus_tag="VXF95_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HEV1082434.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHMIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALIGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(1637..2416)
                     /locus_tag="VXF95_001937"
     CDS             complement(1637..2416)
                     /locus_tag="VXF95_001937"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HEV1082435.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAIQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFPGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(2403..3254)
                     /gene="ylqF"
                     /locus_tag="VXF95_001938"
     CDS             complement(2403..3254)
                     /gene="ylqF"
                     /locus_tag="VXF95_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HEV1082436.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEPSVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(3335..4843)
                     /locus_tag="VXF95_001939"
     CDS             complement(3335..4843)
                     /locus_tag="VXF95_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1082437.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTDKWRTVTVSYTRNTSRAR
                     KQAEREVMDKIEKLTSSLESQYNPEMITTFGELKESWFQTWCVSVKPQTIKREELVIE
                     RLGKIIGDEFLLDRITPLLMKNCLNKYLDKYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KYSPMTAVKIDVPLEKKREARKRLDAKFLEIHELQAFFDVLGQCRNASYYDLAIVLLL
                     TGIRIGEAAFLPSDVDFDKGILHIDKALQYHDLKVDEFYFDTTKTVNADREVALPIAA
                     SEAIQRAIKRNQEFEGYMEQNPSPAFKKCDSVFQTEYGSPITSHSFRQVLKRVEEKLL
                     KNCQKDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     ISRSQENTVTALNQFVEKHNFHFKELKSYTCKYSRMIEQFIETCDDNNKVELSVDEFK
                     DLLHLGSRYSPKHIVSNLLLKIKKDIVKYHPQFDIKIVKLSGNQIKGFSISW"
     gene            complement(4919..5152)
                     /locus_tag="VXF95_001940"
     CDS             complement(4919..5152)
                     /locus_tag="VXF95_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HEV1082438.1"
                     /translation="MEIKYVSVENSVAEWADKKSILKRWEGLNLYTLNRWIKEMRENK
                     RFSLYVINPTHKLVFINLEGFECFLRWKQKRTK"
     gene            complement(5454..5677)
                     /locus_tag="VXF95_001941"
                     /pseudo
     CDS             complement(5454..5677)
                     /locus_tag="VXF95_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            complement(5934..6407)
                     /gene="tnpA"
                     /locus_tag="VXF95_001942"
     CDS             complement(5934..6407)
                     /gene="tnpA"
                     /locus_tag="VXF95_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISSpn6 family
                     transposase"
                     /protein_id="HEV1082439.1"
                     /translation="MREDNQSLSHTTWNCKYHIVFAPKYRRQIIYGRYKASIGRIIRD
                     LCERKGVIIHEANACSDHIHMLISIPPKLSVLSFMGYLKGKSSLMIFDKHANLKYKYG
                     NRKFWCRGYYVDTVGRNQKVIAEYIQNQLQEDRVADQLTLFESVDPFTGEINKRK"
     gene            complement(6565..7365)
                     /locus_tag="VXF95_001943"
     CDS             complement(6565..7365)
                     /locus_tag="VXF95_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1082440.1"
                     /translation="MKADQLRHKSDLGLRGLAIIAKNEIIAFFRSKGLIISQFLQPIL
                     YVVFIIIGLNSSIKNIQFNDIKTSYAEYTIIGVIALLIIGQMTQVIYRVTIDKKYGLL
                     ALKLCSGVRPLYYILGMSIYSILGLIVQEIIIYIITLAFEINIAMDRFFYTVLLSIVV
                     LLFWDSLAILLTMFINDYRRRDIVIRFVLTPLGFTAPVFYLIDSAPSIVRWIGQLNPL
                     TYQLTILRNFYFKNSTTLELVFLLLTSLLVLISVSFIIPKIKLILIER"
     gene            complement(7362..>7600)
                     /locus_tag="VXF95_001944"
     CDS             complement(7362..>7600)
                     /locus_tag="VXF95_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082441.1"
                     /translation="KLNFSMQNRISRYQIEFLENFRFKVHIEDNDSFTIEVPIEENIL
                     DVINEVGKACEIKNFSTSKLTLQESYLQRIGGEK"
BASE COUNT         2321 a         1525 c         1295 g         2459 t
ORIGIN      
        1 ttctgagaat cggttttcta aataaatcaa gccaatcatt tacataatat aaattatgta
       61 aatgattgta ctacaacaac aaatctttga cttttccaat ttcacttttt ggaataacca
      121 ggtgaatcat atcacccaga tacattctgg ttgagccgtt aactgtttgg ctcttgccat
      181 tatggacttg agttgtgatg aggacgttgt gtggtaagtt gagttcatga acttgtttcc
      241 cagcaatttt atcagaaact ggtatttcga taagtgtaac ttctccttcg ctagatactt
      301 cttctggaag cattttttcc agcatggctt catagactgg cgtacctttg agcaaatcca
      361 tgataatata agaaacaaga gtgacaagac caagtggcat gaggttgcga atatctccta
      421 ccatctcagt tacgaggatc atagcggtta agggagcttt tgatatggct ccaaaatagc
      481 cactcattcc tagaatgaca aatataggga attgctcttg actgacaagt ccaagattga
      541 cacagataac accaattaag gcaccaagca aagaaccaag agctaaaatg gggaggaaaa
      601 ttcctcctgg cagtccactt ccatagctaa tcatactcca aataaagcgg atcaaaaagt
      661 aagctaataa aacttggaaa ctaaaatttt gttcagttaa agaaaggaca agctgatttc
      721 cgccaccaat gatttgaggt aagaagattc cgactggtat gataaggata aaagccaaga
      781 tgggataata agctctatcc aaatggattt tttgaccaat caagtcataa actcttccaa
      841 cgtttaatac agctttctca tagagaaagc ctgaaaatcc aaggaaaatt cccatgacga
      901 gatatatcca atactgatct agggtcatgg gaggaatgtt atctggcata tccaatactg
      961 gtgtcaaacc gaacatgagt agagacacaa agtttgctac gatgctggct gctagagttg
     1021 agacccagaa aaagcgcgaa aaatggtgat agacttcttc tacaacaaag agaagtgctg
     1081 caataggagc attaaaggct gcggctaaac ctgctgcagc tccactggca atcaaggaac
     1141 gttcctctac tggactggat ttgagccact tggcaattcc tttaccacca actgctccaa
     1201 gttgaatact gggtccctct cgacccagca tgagtccact ggcaatagcg agaataccta
     1261 gcacatattt tttccaaaga atgccccacc agttgaggga catgaggcct ttcagttcgg
     1321 cttcgacttg aggaattcct gagcctttaa tatctttttc tgaccgtgtt agtttggcac
     1381 tgagccaaca gatgagtata taaaacaaaa ccagtacaaa aagattgcgc actaagtacc
     1441 cttgatcttg ataaactcct tgtatcatgt ggaagccctt ttcaattaag aaacgaaagg
     1501 atccgacgat aattccaacg atgaggccga caatgattcc tcgaccaact tgggatagta
     1561 tagtgctgga tgcaaaggcg aattctttct tagaacggac tatttccgac tgttcctcca
     1621 tggtatttcc tttcaattaa ctttcttttt tacctaaaac cagtgattta acgggttcaa
     1681 agctggttcg gtgaattggg gtaactccta gttttgtgag gccttccaga tgtttagctg
     1741 tgccatatcc tgcattagta gcgaaatcat agccagggaa ctgctgatcg tattctttca
     1801 tcaattcatc acgtgttacc ttggctacta tagatgctgc tgcgatagag agggagttgg
     1861 catctccttt gataatggag gtttgtgaaa tgggcaagtc cagtttcatg gcatcaatca
     1921 aaaggtgctc tggttgaggg ctgagctggg agattgcttc ttgcatggct agtttggttg
     1981 cttcatagat gttgacttgg tcgatgacct gattatctat gataccaatt ccaatcgaca
     2041 aggcttggtc ttgaatggct tggaaaatct ccagatgttt ctttttagga attttcttgc
     2101 tgtcgttgag acctttaatc ttacaatttt taggtaaaat aacggcagca gcgactacag
     2161 gaccagcaag aggaccacga ccaacctcat caatacctgc aattaaggtc aatccttgct
     2221 tataaagttc tttttcataa gaaagcatgg attccaagcg caaattttca tctaattcag
     2281 cttggatggc tcttttacgc ttgctgattt ccttttgaac tcctgagcga ttatcctttt
     2341 caagctctaa aaaaataggg ctttctaact ctttgactgt cacaaggagt tctttgattt
     2401 ctttaatcgt tgccatcgag gtcttccaat gtatctaagg tatagttacc gagtttgcca
     2461 tcacggactt ccttcacgaa gagactgtaa aaacggtcat agtcatcacg gaaaccgagg
     2521 gcgcgggtca tatccataat aatcacagac ggttcttctt caattttcat ttgtttgaag
     2581 cgttcagcca gcttttctgg ataatgttct ttgaaataat tgataccaaa aatggtaacc
     2641 tcatccatag gaagcaactg gtctttgata gctccagtca atgccaactt aagtgcaaca
     2701 gtttcatcct caaacttagg ccagagaatc cccggtgtat ccaagatttc caggtcttta
     2761 ttggttttaa gccattgttg accttttgtg acccctggct tgtttccaac aacagcaatc
     2821 tttttaccag ccaaacggtt catcagagtt gatttaccag cgtttggaat cccgataatc
     2881 atggtacgca aggtttcaat ctgaatccca cgttctttct ggcgagcaat cttatcagcc
     2941 atgagcttct tggccgcatc tgttacaact tttacagtca cttgctcttt ggagttgata
     3001 gctagcgtct ggattccttg tgattcaaaa tactgacgcc attccttggt cattgctgga
     3061 tcagccaagt cggccttgtt taaaatcaag agttttggtt tatcaccaac aatcttggtc
     3121 aacataggat tttgactaga tagaggcaag cgtgcatcta ctaaaatcgt cacaaaatca
     3181 acaaatttta aattctcctg cacctgtcga cgagctttag acatgtgacc aggaaaccat
     3241 tgaatagtag ccattgagtt ttttcctttc gtagcaaggg tttagcaccc ctcatttatt
     3301 ttactatcgt ctaaacacca agcgaacacc aaaactacca cgaaatggaa aaacctttga
     3361 tttgattccc gcttaatttc acaatcttta tatcaaactg tgggtgatat ttgacaatat
     3421 cttttttgat ttttagcagt aaatttgaaa caatatgttt gggtgagtaa cgtgaaccaa
     3481 ggtgtaataa gtctttaaat tcatcaacac ttaactctac tttattgtta tcatcacaag
     3541 tttcaatgaa ttgttcaatc attctcgaat atttacaggt gtaactcttc aattctttaa
     3601 agtgaaaatt gtgcttttct acaaattgat ttaaagcagt tacagtattt tcttgtgaac
     3661 gactgatgtt atgggtgtag cccatcgtgg tttcaaaatt cgcatgacca actctagtca
     3721 taatatcctt tacagctatg tgcatttcat tactttgaag ataactaatg tgcatatgtc
     3781 tgaaagaatg aggggtcaca tgcttgaccc atttaaaacc ataatccttc tgacaatttt
     3841 ttaacaactt ctcctcaacc ctcttcaaaa cttgacgaaa tgagtgagaa gttatcggag
     3901 aaccatactc agtttgaaat acactatcac actttttgaa agcaggacta ggattttgtt
     3961 ccatatagcc ttcaaattcc tgatttcttt ttatagctct ctggattgct tcactcgctg
     4021 ctattgggag ggctacctct ctatcagcat tgacggtctt agtcgtatca aaataaaatt
     4081 catcaacttt taaatcatga tattggagag ccttatcaat atgtaaaatc cccttatcaa
     4141 aatcaacatc tgatggtaaa aaagcagcct ctccaatccg aatccctgtc agtaataata
     4201 caatagcaag gtcataatag ctagcatttc tacactgccc taaaacatca aaaaaggctt
     4261 gcaattcatg aatttcaaga aatttagcat caagcctttt tcttgcttct ctctttttct
     4321 ccagaggcac atctatttta acagcggtca ttggagagta cttaatgaca ttgtatagca
     4381 caccgtgatt aaatatcttg ttacacgtac tttttatatg tgtcattgtt gaaggtgaag
     4441 cgtcgtattt atccagatat ttattaagac aatttttcat cagtagtggt gtaattcgat
     4501 cgagtaaaaa ttcatcaccg ataattttac caagccgttc tatcaccaac tcttcccttt
     4561 ttattgtctg gggcttgaca gatacgcacc aagtttgaaa ccaactctct tttaactctc
     4621 caaaagttgt aatcatttca ggattgtact gactttcaag ggaagaggtc agtttttcta
     4681 ttttatccat tacctctctt tcagcttgct ttcgtgctct actagtattt ctagtatagc
     4741 tgacagttac tgttctccac ttatcagtaa gtggatcttt atatttttca accacttgat
     4801 acaagggttg tccttttgaa tttgttttag ttacataata cataatttaa ttcctcgaaa
     4861 agaaataaat cattgttgta tagaataaat aactactcta tattatacca tgacttcctt
     4921 attttgtccg cttttgtttc catctcaaaa agcattcgaa tccctcaaga tttataaaca
     4981 ccagcttatg tgtaggattg atgacgtata aagaaaatct cttattttct ctcatttctt
     5041 tgatccatct gttaagagtg tagagattca aaccttccca tcgtttcagt atgcttttct
     5101 tatccgccca ctcagctacc gaattttcaa cagatacgta ttttatctcc atattatcat
     5161 cctttcgaat aatttcttct ccctccatgg catgactgat ggggtcatca taagaatctc
     5221 acttactgct cttttacgac ggcagcctga acgttcagaa gtatcattgt atatcatttg
     5281 catcatggca gatagagtat cgctctattt tattggtgat tgtccccgct cctatcttgg
     5341 cgaatcaagc aaaactgctc cacaaatgag gaaagtacca ttttaggcta ttcagttgtc
     5401 aaagggcaaa taaaaaatct cactcatttt caaactctat gaaattgagg agattatttt
     5461 ctaaagcgaa ttttatcagg aaaatcacag ttaatcccaa taaatagtct gtactgacgt
     5521 catagaaatc tgagagttta accaatacat cagccgtcaa cgcatgctca ccccgttcaa
     5581 ttttggcata agctgaattt gtaaacgaaa gtattgtagc tatttgcttt tggggcagat
     5641 catgatcctc cctcaaatct ctcaaacgtc tgtacatcta gctttctcct aagaaaaagt
     5701 atagaccata tattgtaact atttaggata ttgtccaaat cggacaacag gaattttacc
     5761 atcctttata tagactttta tttttatgta tcaagttttt taaatcaaaa ccaccagtgt
     5821 gaactggtgg tttgttctgc ggctataagc cgcttctacc ggccagggcc aaaggcccat
     5881 cgaaatagct tcctcgcgca ccactttccc gagcaggtgc taaagcacct tagttacttc
     5941 ctcttattta tttcgccagt aaacggatct actgactcga ataacgtgag ctggtctgct
     6001 actctgtctt cttgtaattg attctgaata tattcagcta tcactttctg attacggcct
     6061 accgtatcta cataatagcc tctacaccaa aacttgcgat tgccatattt gtattttaaa
     6121 ttcgcatgct tatcaaaaat catcaaactg ctcttgccct ttaaatagcc cataaaggac
     6181 aaaacactaa gtttcggagg aatactgata agcatgtgaa tatggtctga acaagcattc
     6241 gcttcatgga ttattacacc cttacgctca cataagtcac gtatgattct tccgatacta
     6301 gctttgtatc tgccataaat gatttgacga cgatatttgg gtgcaaaaac aatatgatat
     6361 ttacaattcc atgtggtatg tgataaactt tgattatcct ctctcatgag gtacctcctg
     6421 tatgatatgt tgtagtggcg gagaaaccac ttctatctta tcattttagg aggttctttt
     6481 tgttaccacg ctaaaagctc tatggaacca ctagcatagc tagtggtttt cgggagacaa
     6541 caaaaaagtt ggatgaccca acttttatct ttctatcagt atcaatttta tctttggtat
     6601 aataaaagat acagatataa ggacaagtaa tgatgttaac aataagaaaa ctaattccaa
     6661 agttgttgaa tttttaaaat aaaagtttct caaaatagtt aattgataag ttaagggatt
     6721 taactgacca atccatctca caatactagg agcagaatct attaagtaga aaacaggagc
     6781 tgtaaaacca agcggtgtta gtacaaaacg tattacaata tcacgtcttc tgtaatcatt
     6841 gataaacatt gtaagtaaaa ttgcaaggga gtcccaaaat aataaaacaa caatagataa
     6901 caaaactgta taaaaaaatc tatccattgc gatatttatc tcaaacgcta acgtaattat
     6961 atatataata atttcttgaa ctatcaaccc taatatagaa tagatactca tccctaaaat
     7021 ataatataaa ggacgaactc cactgcataa cttaagagca agtagcccat attttttatc
     7081 tattgtcacc ctataaataa cttgagtcat ctgcccgatt atcaataaag ctataacacc
     7141 aatgattgta tattctgcat aagaggtttt tatatcatta aactgaatgt tctttatcga
     7201 agaatttaat cctattatta taaaaacaac atataagatt ggttgtagaa actgagaaat
     7261 aattaaacct ttacttctaa aaaaagcaat aatctcattt ttagcaataa tcgctagacc
     7321 tcttaaacct aagtccgatt tgtgccttaa ttgatcagcc ttcatttttc tcctcctatt
     7381 ctttgcaaat aactttcttg taaggttaat ttacttgttg aaaagttttt aatttcacat
     7441 gcttttccta cctcattgat aacatctaag atattttctt ctatagggac ttctattgta
     7501 aaactatcat tatcttcgat gtgaacttta aatctaaaat tttctaaaaa ttcaatttga
     7561 tatctagaaa ttctattctg cattgaaaaa tttaatttga
//
LOCUS       DAVLMQ010000071         7488 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000071 DAVLMQ010000000
VERSION     DAVLMQ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.071"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            151..306
                     /locus_tag="VXF95_001945"
                     /pseudo
     CDS             151..306
                     /locus_tag="VXF95_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            506..3781
                     /gene="rexB"
                     /locus_tag="VXF95_001946"
     CDS             506..3781
                     /gene="rexB"
                     /locus_tag="VXF95_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HEV1082442.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQTFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAEKLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDQQGLENPAIPISPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGEQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKENSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLKKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3778..7428
                     /gene="addA"
                     /locus_tag="VXF95_001947"
     CDS             3778..7428
                     /gene="addA"
                     /locus_tag="VXF95_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HEV1082443.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILNQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FAKLGQLSDQITILDYQERYHQDTWELAKTFQTFMSHFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQKGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2282 a         1576 c         1590 g         2040 t
ORIGIN      
        1 tgtactattt ttggttcatt ttactatagt agattgaaat aagatacgaa cagcttgatt
       61 agggaaatca aattaatttc tagaaatatt ttagcatcca cggtgtacta ttatagtttc
      121 aatttactat agttcaatca ttctatcaag aatattgaat atataaaggc acgtaatatt
      181 aaaacttctt ctgatatcga attagagtcc gatgttgatg gcgataaatc agacaatcta
      241 ccagtcgaca ttaagatact gggacaacac attgaagtgt attccgtacc taagaaacaa
      301 tcataaaact caaagccttg ttaccgaggc ttttttatta tgtgattttc agtagccaga
      361 cttattctat ctaatacaag taaagctaag tatttaagat ttagcagatg atgaagaaaa
      421 gaaaggatgg cctaaatatt ttaacagatt tacgaggcta atcatggtat aatatagggt
      481 gatgaaaaat tccaacgagg ctgagatgaa attactttat actgatattc ggacttcttt
      541 gacagaaatt ctaacaagag aggcagaaga gctagttgca gctggcaagc gggtcttcta
      601 cattgccccc aactctcttt cttttgaaaa ggaacgcgcc gtgctggaat gcttgtccca
      661 gcaggcttct ttttcgatta ccgtcacgcg ctttgctcaa atggctcgtt atctggtctt
      721 gaatgattta ccagctaaaa ctactcttga tgatatcggt cttgggttgg ccttttacaa
      781 atgccttgcc gaactcgatc ccaaggactt gcgtgtttat ggcgctatta agcaggatcc
      841 tcaattgatc cagcagttaa ttgagcttta ccatgagatg accaaatccc agatgagttt
      901 tttggacttg gagaatttaa cagatgagga taagagggcg gatttactct tgatttttga
      961 gaaagtaaca gcctatctta atcaaggtca gttagcccag ggaagtcagt tgtcccattt
     1021 gattgaggct attgagaatg acaaggtaag tagtgatttt aatcaaatca ccttggtcat
     1081 tgacggcttt actcgttttt ctgctgagga agagcgggtt gtggacttac ttcacggcaa
     1141 aggtgttgag attgttatcg gggcttatgc tagtaagaaa gcctatacca gtccttttag
     1201 cgagggcaat ctctaccaag ccagcgtaaa atttctccat catctggctt ctaaatacca
     1261 aacgcctgct caggactgtt ctcaaactca tgagaagatg gatagttttg acaaggcctc
     1321 tcgtttgttg gagtcttctt atgacttttc agaactcgct ttggatgtcg atgagaaaga
     1381 ccgtgaaaat ttacaaatct ggtcttgttt gacgcaaaag gaggagttgg agctagtagc
     1441 ccgtagtatt cgtcagaaat tacatgagaa ctcagacctg agctacaagc attttcgtat
     1501 tctcttgggg gatgtagctt cttaccagtt atctctcaaa accatttttg accagtatca
     1561 gattcctttt tatcttggta gaagcgaagc catggctcat catcccttga ctcagtttgt
     1621 cgagtctatt ttagctttaa aacgttaccg ttttcgtcag gaggatttga ttaatcttct
     1681 tagaactgat ttgtatactg acctcagtca gtctgatatt gatgcttttg agcaatatat
     1741 ccgctatctt ggtatcaatg gcttgccagc ctttcagcaa accttcacca aatcccacca
     1801 tggaaaattt aatcttgagc gtttgaatgt cctccgcctg agaattttag cacctcttga
     1861 aaccctcttt gccagccgaa aacaaaaggc tgaaaaactc ctacaaaaat ggagtgtctt
     1921 tctaaaagaa ggagctgtga ccaagcagtt acaagatttg acaaccactt tggaagctgt
     1981 agaacaggaa agacaagccg aagtttggaa ggctttctgc catgttttag aacaatttgc
     2041 gactgttttt gctggttcac aggttagtct ggaagacttc ctagccttgc tccattctgg
     2101 aatgagtttg tcccaatacc gtaccattcc agcaacagtg gacactgttc tggtgcagag
     2161 ttacgatttg attgcaccat tgactgctga ctttgtctat gctattggac taactcagga
     2221 caatttacca aaaatttctc aaaacaccag tcttctgaca gatgaagaaa ggcaaaatct
     2281 aaaccaagcg accgaagaag gcgttcaatt actgattgcc agcagtgaaa atctcaagaa
     2341 aaatcgctac actatgcttt ccttggtcaa ttctgctcgt aagcagttgt tcttgtcggc
     2401 tccaagcctt tttaacgaaa gtgaaagtaa ggaatctgcc tatcttcaag agttgatcca
     2461 ttttggattt aggcggagag agaagaggat gaatcacaaa ggactgtcta aggaggatat
     2521 ggggtcctat cacagtcttt tgtctagtct ggttgcctat caccagcagg gtgagatgag
     2581 cgatactgag caagatttga cttttgtcaa ggttctgtcg cgtgtcatag gtaaaaaact
     2641 agatcagcaa ggtctggaaa atccagccat cccaatcagt ccaagcagca agaccttagc
     2701 caaggacacc ttgcaagctc tctatcctgc caaacaggag ttttacctgt ctacgtcggg
     2761 tttgacagag ttttatcgca atgaatacag ttatttccta cgctacgttt taggcttgca
     2821 ggaggaatta cgtttgcgtc ctgatgcccg tagtcacggg aatttcttgc atcgtatctt
     2881 tgaacgcgcc ttacagttgc ctaatgaaga ttcctttgac caacgtctag aacaagctat
     2941 tcaagaaacc agtcaagaac gcgaatttga agctatttat caagaaagtt tggaagccca
     3001 gtttaccaag gaagttttgc ttgatgttgc acggacgact ggacatattc tccgacacaa
     3061 tccagccatc gaaaccatca aagaagaagc aaattttggt ggaaaagacc aagcctttat
     3121 tcaattagac aatggacgca gtgtctttgt acgaggcaag gtggaccgga ttgaccgttt
     3181 gaaagctaat ggagcgatag gagtagtaga ctacaaatcc agtctgactc agttccagtt
     3241 tcctcatttc tttaatgggc tcaattctca gttaccaacc tatcttgctg ccctaaaaag
     3301 agaaggggag cagaactttt tcggcgccat gtacttggaa atggctgaac ctgtccaatc
     3361 tctgatggcg gtaaaaagtc tggcaggagc agtggtagaa gccagcaaat ctatgaaata
     3421 ccaagggctc ttcttggaaa aagaaaacag ttatttaggc gaattttata acaaaaacaa
     3481 ggctaatcaa ctgacagatg aggaatttca gctcctactg gactacaatg cctatcttta
     3541 caagaaagct gctgagaaga ttttagcagg ccggttcgcc atcaatcctt atactgaaaa
     3601 tggcagaagc attgccccat acgtccagca acatcaggct attacaggct ttgaagccaa
     3661 ttaccatctg ggccaagccc gtttcctaaa aaagttggac ctagctgatg gcaagcgtct
     3721 ggtcggagaa aaactcaagc aagcttggtt tgaaaaaata agagaggagt taaatcgatg
     3781 aagcttattc cctttttaag tgaggaggag attcaaaaac tgcaagaagc agaagcaaat
     3841 tcgagcaagg aacaaaagaa aactgccgag caaatcgaag ctatctacac ttctggccag
     3901 aatatcctgg tctcagcatc ggctggttct ggaaagacct ttgtcatggc agagcgcatt
     3961 ctgaaccaat tggcgcgtgg tgtcgaaatt tctcaactct ttatctcaac ctttaccgtc
     4021 aaggctgcaa ctgaacttaa agaacgttta gagaaaaaaa tcagcaagaa aattcaagaa
     4081 acagatgatg tcgacctcaa acaacacttg ggacgccagt tggcagactt accaaacgct
     4141 gccattggaa ccatggactc tttcacacaa aaattccttg gcaaacatgg ttatctgctt
     4201 gatattgcac ctaatttccg tattttacaa aaccaaagcg agcaacttct tctcgaaaac
     4261 gaagtctttc atgaggtctt tgaagcgcat taccaaggta aacagaaaga gacctttagt
     4321 catttgctga aaaactttgc tgggcgtggc aaggacgaac ggggtctgcg ccagcaggtc
     4381 tataaaatct atgacttcct ccaatccacc agtaatcctc aaaagtggtt gagtgaatct
     4441 ttcctcaaag gctttgagaa agctgatttt accagtgaaa aagaaaaact gactgagcaa
     4501 atcaaacaag ccctttggga tttggaaagc tttttccgtt accatctgga taacgatgcc
     4561 aaggagtttg caaaggctgc ctatttagaa aatgttcagt taattctgga tgaaattggc
     4621 tccctaaatc aggagtccga tagtcaggct tatcaggcag tgcttgcgcg tgttgtcgcc
     4681 atctctaagg agaaaaacgg tcgagctctg actaatgcca gtcgtaaggc tgatttgaag
     4741 cccctggctg atgcctacaa cgaagagaga aagacccagt ttgctaaact aggacaatta
     4801 tcagaccaga taaccattct cgactatcaa gaacgttatc atcaagacac atgggaacta
     4861 gctaaaacct tccaaacctt tatgagtcat tttgtggagg cttatcgtca gcgcaaacgc
     4921 caggaaaatg cctttgaatt cgctgatatc agccattaca ccattgagat tttagagaat
     4981 ttcccacaag ttcgtgagtc ttatcaggag cgcttccatg aagtcatggt cgatgagtat
     5041 caggatacca accatattca agaacggatg ctggaattgt tgtctaatgg ccacaatcgc
     5101 tttatggtgg gagatatcaa gcaatccatc tatcgtttcc gtcaggcaga cccgcagatt
     5161 ttcaatgaga aattccaacg ctatgcgcaa aatccccaaa aaggcaagct cattctcctc
     5221 aaggaaaatt tccgtagtag ttcagaagtg ctgtcagcaa ccaatgatgt ctttgaacgt
     5281 ctcatggacc aagaggtcgg cgaaatcaac tatgataaca agcaccagct tgtttttgcc
     5341 aataccaaac tgactcccaa tccagacaac aaggcagaat ttctcctcta cgacaaggac
     5401 gatacaggtg aggaagaaga gagtcaaaca gaaacgaaac taacaggcga aatgcgctta
     5461 gttatcaagg agattctgaa acttcatcaa gaaaaaggtg ttgcctttaa ggaaattgcc
     5521 cttctgacct ccagccgcag tcgtaatgac cagattctcc tcgccctgtc tgagtacgga
     5581 attcctgtca aaactgacgg agagcaaaac aattatctcc aatccctaga agtgcaagtc
     5641 atgctagaca ctcttcgtgt cattcacaat cccctgcaag actacgcctt ggttgccctt
     5701 atgaagtctc caatgtttgg ttttgatgag gatgagctag cacgtttgtc ccttcagaaa
     5761 gcagaggata aagtccacga aaatctctat gaaaaactgg tcaatgcaca aaaaatggca
     5821 agtagtcaaa aaggtttgat tcacacagct ctagctgaaa aactaaagca attcatggat
     5881 atcctagctt cttggcgctt gtatgccaaa acccactctc tctatgactt gatttggaag
     5941 atttacaacg accgttttta ttatgactat gttggggctt tgccgaatgg tcctgctagg
     6001 caggccaatc tctatgccct agcactgcgt gctgatcaat ttgaaaagag caatttcaaa
     6061 ggtttgtcgc gttttattcg tatgattgac caagtcttag aagcccagca cgatttggca
     6121 agcgtggccg tcgcaccgcc aaaagatgca gtagagctca tgaccatcca caagagtaag
     6181 gggctggagt ttccttacgt ctttatcctc aatatggatc aagatttcaa caagcaagac
     6241 tctatgtcag aagtcattct cagtcgtcag aatggtcttg gtgtcaaata tattgccaag
     6301 atggagacag gggcagtaga agaccactat cctaaaacca tcaaactctc cattcctagc
     6361 ctgacctata ggcagaatga agaggaatta cagctagcaa gctattctga gcagatgcgt
     6421 ttgctgtatg ttgctatgac gcgggctgag aaaaagctct atcttgtcgg caagggttct
     6481 cgtgaaaagc tggaagccaa gcaataccca gcagccaaaa atgggaaact aaatagcaat
     6541 actagactgc aagcacggaa tttccaagat tggctttggg ctatcagtaa agtgtttact
     6601 aaggacaagc tcaactttag ttatcgtttt attggcgaag atcagttgac cagagaagct
     6661 atcggagagt tggaaaccaa gagtcctctc caagatagct cccaagcaga caatcgtcag
     6721 tcagatacca tcaaagaagc tctgaaaatg ctgaaggagg tggaagttta taatactctt
     6781 caccgcgcag ctattgaact tcctagtgtt caaaccccaa gtcaaatcaa gaaattctac
     6841 gaaccagtta tggatatgga aggtgtcgag attgctggtc aaggtcagtc agtaggcaag
     6901 aaaatcagct tcgatttgcc agatttttca acaaaagaaa aggtaactgg agctgagatt
     6961 ggtagtgcta ctcacgaact catgcagaga attgacctca gccagcaact aacccttgct
     7021 agcctaacag aaacactcaa acaagttcaa actagccaag ctgtcagaga caagatcaat
     7081 cttgataaaa ttcttgcttt ctttgacaca gtactcggtc aggaaattct tgctaatacc
     7141 gaccatctct atcgcgagca acctttctcc atgctcaaac gagaccaaaa gagtcaggaa
     7201 gactttgttg tccgtggtat ccttgatggc tatctgcttt acgaaaacaa aattgttctg
     7261 ttcgactaca agacagaccg ctatgatgaa ccaagtcaac tcgtagaccg ctatcgtggt
     7321 cagttagctc tatacgaaga ggctttatca cgagcctatt cgattgaaaa tattgaaaaa
     7381 tacttgattt tactcggtaa agacgaggtt caagttgtaa aagtataact tatactcttt
     7441 gaaaatctct tcaaaccacg tcagcttcgc cttgctgtat atatggtt
//
LOCUS       DAVLMQ010000072         7402 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000072 DAVLMQ010000000
VERSION     DAVLMQ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7402
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.072"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            323..499
                     /locus_tag="VXF95_001948"
     CDS             323..499
                     /locus_tag="VXF95_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082444.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            900..3113
                     /locus_tag="VXF95_001949"
     CDS             900..3113
                     /locus_tag="VXF95_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HEV1082445.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     ISLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(3335..3811)
                     /locus_tag="VXF95_001950"
     CDS             complement(3335..3811)
                     /locus_tag="VXF95_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HEV1082446.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRIEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            4034..7237
                     /locus_tag="VXF95_001951"
     CDS             4034..7237
                     /locus_tag="VXF95_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HEV1082447.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSPWTGSKAQGWSAWVDQKNSSADASTRVIETKDG
                     TITISSPEKLRAALHRMVPIEAKKKYKLRFKIKTDNKIGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVADQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKEGTTNVIVSKDGKE
                     VKKIPLKILASVKDAYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WLHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKSPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKGINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVDRATFNQMIKELESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
BASE COUNT         2473 a         1165 c         1576 g         2188 t
ORIGIN      
        1 tctaattgtt tagaaataat atctggaact atttaaatat cttcaagata gaaaaagaaa
       61 ttgtacttgt tgatgttgaa tcatttgtgt taacaagtca tttagaagca tttaagaaat
      121 tagtgaaatg aaaaactcat ggcagaacaa attgttgggt atatggtcta ttactaacaa
      181 ctactgctag tttatgagat agatatttaa ttattctcgg ataaatagga taagcgtgct
      241 gaaaacttag atatgacaaa caaaataaaa tttttaaaag ctacagagaa acatggtata
      301 atgtatctaa aggaggtagc atatgtcctt agatatagat aaagaaaaga tgacaatcat
      361 gggaatagct tttgaaaacc gatccgtttt taagagtgtt tggtatgctt taagtacaaa
      421 tatgattgaa ggatggcgac ctacggttag tgatgttgaa aaattacgag atgaagctct
      481 tgctctgggg atgacttaat gaagcgcaac tgttatgaat cttatgacta tgttgatccg
      541 gataatttat ataccgatcc gggttcttca gttctaagaa ataagcagga aggaaaaaag
      601 cacgtgagct tgaatatcgt atgattgcta gtaagagttt gaaattattt atcaatccta
      661 tcttagttaa tagtttaaaa gtagtttgtt tcacaactgc ataagcttag aaaagttgaa
      721 aagtgataac tctttaataa actcttggtt tgttaaaaga tattttgtcc actgcatttt
      781 ttcaattgac tattatttgt catagatata acagatagaa cattgcattc agaataatga
      841 aaaacgcatc aaaaatggtg cgttctgttt ttatgctacc ataaaaggag gaaaacaaat
      901 tgaaaatttt taagggagag ttttatcgaa tctctgtatt aacagacaag ctagtaaggt
      961 tagaatactc tcgaactgga aattttgagg atagaacgac acaacttatc tataatagag
     1021 attttggcca aatttcgtta gattatatcg agacatcaaa cgtactagat attatgacgg
     1081 actattttca tctgcacttt aataaaggag aatttaacgc cgaaaattta tttatagaat
     1141 taaaaggaaa ttttgccgta tatggtagtc gctggtattt tggtgaatct attgaaacgt
     1201 taaaaggaac agctcggact ctggataagg cagatggagc aatctcgtta gaagatggaa
     1261 ttattagccg aaatggtata gccttattgg atgattctca aggatttatt tgggatgaac
     1321 aatctggtta tattgagaga gaaaatcaaa ttgacctgta tttctttgcc tatgggcatg
     1381 attatagagg agcaatcaga gacttttacc atttgactgg ttcaacaccc ttgttgccaa
     1441 gatatgcttt aggcaattgg tggagtagat attggcctta tacgtcggat gaatacttgg
     1501 atttaataga cagatttgaa acagagaaaa ttccattatc tatcggtgtg ttagatatgg
     1561 attggcatat aactgacatt ccagctcgtt ttggaagtgg ctggacagga tatagttgga
     1621 atagaaactt aataccaaat ccagaacagt tattgcaaca acttcatgat agaaagttaa
     1681 aactctcctt aaatgtccat cctgctgatg ggatacgggc ttatgaagaa gcttatcctc
     1741 aaatcgcaaa acgattgggg ttaaatgtag aactagaaga acctgctatt tttgattttt
     1801 ttaatccctc ttttagggaa gcctacttta aagatgttca ttatgagcta gaaaagcagg
     1861 gagtagattt ttggtggatt gactggcaac aagggacaca aggcatgcta gatccacttt
     1921 ggcttttaaa ccattatcac tatcaggata gttgtaaaaa tgcagaaggt ggtttgattt
     1981 tatcaagata tgcaggtcct ggtagtcacc gctaccctgt tggtttttca ggggatacta
     2041 ttattagttg gaattcctta agatttcaac cctattttac agcgacagca tctaatatcg
     2101 gttatagttg gtggagtcat gatatcggtg gacatatgtt gggggattat gacgaagagc
     2161 tacaaactag atggctacag tttggtgttt ttagtccgat tactcgatta catagttcta
     2221 gaagtccttt taatagtaaa gaaccttggt ttttttcaga aacaacatct aagattatga
     2281 agaaatacct tcgtttgaga catcagatga ttccttatct atataccatg aatgtaaaga
     2341 cacatgagga aggtgcccca ttaatcagtc caatctatta tttctatcca gagaatgatg
     2401 agagctataa tgttccaaac caatactttt ttggaacaga actgatggtg gctcccattg
     2461 tagaaaagat ggatttgaca ttccaatctg caaaagtaga tgtatggttc cctgaaggtg
     2521 aatggtatga cttcttttca gagaaaaaat acacaggtgg tgtgaagtta agtgtttata
     2581 gggacatctc gactacgcct gtgtttgcaa aaagtggtgc aatcattccc ttggttggtt
     2641 ctgagatagg tatgggtgtt gatttacctg aggttgtaga ttggtatgta ttcccaggga
     2701 aacaacattc ttttgaaatg cttgaagatc aaaatggtca aagatataaa acaagattat
     2761 caatcgattg ggaaatggga atggtagagt tagcattaca aggagattct agtatcgttc
     2821 caagcaatag aaaacataga attcatttta aaggaacgaa tgtgtctata attgaattgc
     2881 caaataagaa tgatacagct aaatttgaat ggaaagataa taaaaggaca tctttaaatg
     2941 acgaagtttt tagactacta aagacagctt ctcttccata tgaattaaaa gatagattgt
     3001 taaatcaatt catcaatgcc aaaaactctc atgacttaat gaatatcttg catcatcagg
     3061 ataaggaatt gagagggcgt ttgttggaaa tgatatttac tagccaaaac taattgaaat
     3121 aattagaaag tcatttgttt agtgtatatg aagattctgt atggtatttg ttatcattgg
     3181 tcacattgaa aatgtgaaat aagcacctac aacatagact ttacaacact tcatgtttca
     3241 tatcatgggg tgtttttcta tttaagtcaa agccaatcaa aaaatctcac tattcatcag
     3301 gttaaaggaa acctaatcat agtgagattg tgaattatag tagagtttgt atcgcctctt
     3361 caatttgttt tgggtctgtt tttgaagaaa agcgttcaaa gacttgccca tctcgaccga
     3421 tgagaaactt agcgaaattc cattcgattc gttttcctag tgggccagat ttctggtctt
     3481 ttaaccagac atagagaggg tctgcttcct taccgttgac cttaatcttg gcaaaacgtg
     3541 ggaaggtggt ttgaaaatgt aggctacaga aggcgttgat ttcctctgcg ctgccgggtg
     3601 cttgtcccat aaactgattg caagggaaat ccaatatttc gaagccctga tcttgatagc
     3661 gttcatagag ttcttgaagt ccctggtact ggggcgttaa accacatcca gtagcagtgt
     3721 tgacaatcaa gagaactttg ccacgatagc tatccaaggg agttgcttgg ttgttttggt
     3781 tcaaaacgga aaaatcataa agtgaagtca tgagggcctc ttttcttttt ctacattgta
     3841 acagttttta cttttttcgt cgagtcggat ggaagatatt gttgaagaat aagccctcaa
     3901 tatgatagaa accgtttaca aataacttta aaaatggtat aatttaatta aaccggttta
     3961 cttagttgct ataaatctct aatttgagat ttagttccta ttgattttac aatatgttta
     4021 ttggagtgta tacatgcaaa caaaaacaaa gaagctcatt gtgagtttgt cttcacttgt
     4081 tttatcagga tttttattaa accattatat gacagttgga gcggaagaaa cgactacgaa
     4141 taccattcag caaagccaga aggaagttca gtatcagcaa agggatacaa aaaatttagt
     4201 tgaaaatggt gattttggtc agacggagga cggaagcagt ccgtggacag gaagcaaagc
     4261 tcaggggtgg tcagcttggg tagaccagaa gaatagttct gcagatgcct caactcgagt
     4321 cattgagact aaggatggga ctatcactat ctcaagccct gagaaattaa gggcagcgct
     4381 tcaccgtatg gttcctattg aagctaagaa aaagtataaa ctgcgtttca agattaaaac
     4441 agataataaa atcgggattg ccaaagttcg tatcattgag gaaagtggta aggacaagcg
     4501 attgtggaat tctgcaacga cgtcaggaac aaaggactgg cagaccattg aagcagacta
     4561 tagcccgact ttagatgttg ataaaatcaa gctggagtta ttctatgaaa caggaactgg
     4621 gactgtttcc tttaaggata ttgagctggt agaggtagca gaccagcttt ctgaggattc
     4681 tcaaacagat aaacagcttg aggaaaagat tgatttacca attggaaaaa aacatgtttt
     4741 ttctcttgcg gactatactt ataaggtaga aaatcctgac gttgcttcag tcaaaaatgg
     4801 aattttagaa cctcttaagg aagggacaac caatgtcatt gtcagtaaag atggcaagga
     4861 agtgaaaaag attcctttga agattctggc ctctgttaag gatgcataca cagaccgttt
     4921 ggatgactgg aatggcatca tcgctgggaa tcaatactat gattctaaaa atgaacagat
     4981 ggccaaatta aaccaggaat tggaaggaaa ggtagctgat agcctatcca gtatttcaag
     5041 tcaggcggac cgcacctatt tgtgggaaaa attttcaaat tataaaacgt ctgcaaatct
     5101 gactgccact tatcggaaat tggaggagat ggccaagcaa gtgaccaatc cttcttctcg
     5161 ttattatcaa gatgaaactg tcgttcgaac agtcagggat tccatggaat ggctgcataa
     5221 acatgtctac aatagtgaaa agagcattgt tgggaactgg tgggattatg agatcggtac
     5281 acctcgtgcc atcaacaata ccttgtctct gatgaaagaa tacttctctg atgaggaaat
     5341 taaaaaatat acagatgtaa ttgaaaaatt tgtaccagac cccgaacatt tccgaaagac
     5401 gactgataac ccatttaagg ctctaggtgg aaacttagtt gatatgggaa gagtaaaagt
     5461 aatagctggt ttactgcgta aagatgatca agaaatttct tctaccattc gctcgattga
     5521 gcaagtgttc aagttggtag accaaggtga aggtttttat caagatggat cctatatcga
     5581 ccacaccaat gttgcctata cgggtgctta tgggaatgtt ttgattgatg gcctgtctca
     5641 actgttgcca gtcattcaaa agaccaagag tccaatcgat aaagataaaa tgcaaaccat
     5701 gtaccactgg attgataaat cgtttgctcc tttgctggtg aatggagaac tgatggatat
     5761 gagtcgtgga cgctcgatca gtcgtgcaaa tagcgagggg cacgtggccg cagtagaagt
     5821 actaagaggg attcaccgaa tagcggatat gtctgaagga gaaaccaaac aacgtttgca
     5881 gagtcttgtg aagaccattg ttcaatcgga tagttattat gatgtcttta agaatttgaa
     5941 gacttataag gatatcagtt tgatgcaatc cttgttaagt gatgcaggag tcgcaagtgt
     6001 tccaagacca agttacctat ctgcctttaa caagatggat aaaacagcca tgtacaatgc
     6061 agagaaaggg tttggatttg gcttgtcact cttttccagt cgtaccttga attacgaaca
     6121 catgaacaag gaaaataaac gtggttggta tacgagtgat gggatgttct atctttacaa
     6181 tggcgatttg agtcactata gcgatggcta ctggccaaca gttaatccat ataagatgcc
     6241 tggtacaaca gagacggatg ctaagagagc ggatagcgat acaggtaaag ttttaccgtc
     6301 tgctttcgtt ggaacgagca aactagatga tgccaatgcg acagcaacca tggatttcac
     6361 caactggaat caaacattga ctgctcataa gagctggttt atgctaaagg ataagattgc
     6421 ctttttagga agcaatatcc aaaacacttc aacagatact gctgcaacta caatcgacca
     6481 gagaaaactg gaatcaagta atccatataa agtctatgtc aatgataaag aagcctccct
     6541 tacagaacaa gaaaaggatt atcctgaaac ccaaagtgtc tttttagaat cgtccgattc
     6601 gaaaaagaat attggttact ttttctttaa gaagagttca atcagcatga gtaaggcttt
     6661 gcaaaaggga gcctggaagg gtatcaatga aggacagtca gacaaggaag ttgaaaatga
     6721 atttcttacg attagtcagg ctcataagca aaatggagat tcttatggct atatgctcat
     6781 tcctaacgtg gatcgtgcca ccttcaatca aatgataaaa gagttagaaa gtagcctcat
     6841 cgaaaataac gaaacccttc agtctgttta tgatgctaaa caaggagttt ggggcattgt
     6901 gaaatatgat gattctgtct ctactatttc caaccaattc caagttttga aacgtggagt
     6961 ctataccatt cgaaaagaag gggatgaata taagattgcc tactataatc ctgaaaccca
     7021 ggaatcagct ccagatcagg aagtctttaa aaagctagag caagcagctc agccacaagt
     7081 acagaattca aaagaaaagg aaaaatctga agaggaaaag aaccattcgg atcaaaagaa
     7141 tctccctcag acaggagaag gtcagtcaat cttggcaagt ctagggttct tgctacttgg
     7201 ggcattttat ctattccgta gaggaaagaa caactaattt gttcatcatc tagatgaatt
     7261 acatgaaact gtggaaaata gaaaaaatcc gaagaaggcc aaatatcttc ggatttttct
     7321 tttaaaaaag gataagttga tacttatcct tttttacttc attattatgt gactatagcg
     7381 ttttgaaact agaatagaac gt
//
LOCUS       DAVLMQ010000073         7297 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000073 DAVLMQ010000000
VERSION     DAVLMQ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.073"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            168..854
                     /locus_tag="VXF95_001952"
     CDS             168..854
                     /locus_tag="VXF95_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HEV1082448.1"
                     /translation="METKKIKNLKGQIIVSCQALEGEPLYTPNGGVMPLLAKAAFQAG
                     AKGIRANSVRDISEIKEEVDLPIIGIIKRDYDGFEPFISATMKEIDELVSEGVDILAL
                     DCTNRSRPGYDNITDFIHDIKVKYPNKLLMADISTFEEGKVAVESGVDFVGTTLSGYT
                     PYSPKKDNPDFELVERLVKELDVPVIAEGRISTPEQARKMLDLGAYAVVVGGAITRPL
                     EIAKKFIEVV"
     gene            855..1787
                     /locus_tag="VXF95_001953"
     CDS             855..1787
                     /locus_tag="VXF95_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001071049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HEV1082449.1"
                     /translation="MNQEILKKSKIQLTVEHIQKYWILYLMMIPATVLLILFTYGPMY
                     GIIMAFQDFTVFKGYTGSPFVGLKHFQRLFSDPLFYRLFKNTFMVGVLDFLFSFPAPL
                     IFALILNEVRKVRFKSVVQSISYLPHFIPLVVMVGIIFELFGSYGIINSLLSSLGMEP
                     ISFFTKSEWFLPLYIGSGVWKTIGWGSIIYMGALTNIDSTLYEAADMDGANRWHKMWH
                     VTLPSLRPTVVTLFILNAGGIMQVGFEKVFLMSSPATYEVSDVLSTYVYRQGILNSDF
                     SYSAAVGLFNNIVALLFVLLANKIAKKLGEEGIV"
     gene            1798..2727
                     /locus_tag="VXF95_001954"
     CDS             1798..2727
                     /locus_tag="VXF95_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HEV1082450.1"
                     /translation="MIFSKNTKKSNRDKETFVDYLFIFILIIITLLMLYPLWWVVMTS
                     LSEPVWLSKNVVKLFPLKIDITAYKFIFGDSKLWQAYGNSVLYAALSTIVSVAVCSMY
                     AYPLTIPEIRGKKFWNTLILIPMFFSGGMIPLYIQVANLGLLNTAWALVLPSAVSTYY
                     IILFRTQFKSIPMELRESARIDGASEFRIFWNLVLPLSKVIFMIIALYCIVGSWNSFT
                     PPLLYLNDDTKMPLSIYLRNLVVTNTTDTAELSLSAGNTYYQQIAAQGGGIGMRIAIK
                     MGTIVVSVIPIMMIYPFIQKHFVKGILLGSVKG"
     gene            2741..4180
                     /locus_tag="VXF95_001955"
     CDS             2741..4180
                     /locus_tag="VXF95_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001178946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082451.1"
                     /translation="MQNLKKYLLLDSGLVVGYTLENAQLKLNKLKKDTENNPLFGEEY
                     FAENPKLWEVRFDNSYPNVIYDKELKLYRCWYQTFVSDEASEETPLAERGEKEYIVKS
                     SRMTALCYAESKDGVKWEKPNLNLVKFKGSKDNNIVLMHAHGAGIMLDEQELDPKKRY
                     KLVSKLEFSPNLHYMVVVFSEDGIHFDEPIPWKKWNPAADSHNFPFRDPKTGKYAVIT
                     RTWANNVRLSAITFSDDFINWSEPKEILRGDGFEDQIYSMPVISYADIYLGFASMYHE
                     GDTLNENYDKVDLELKFSANLEQWDSVCKGDYLIERGGGVYPQNADFDASCIFTAAPI
                     IEDDKIWFYYMGGNGNHIGFRESSLARGYIKKDQFAYYTNKREGIPAKISTVSFQTYD
                     DEIYILADIPENGYIKVAVGTKYGNAYSDFGQEDISLVQVSDGKYKLEFNKKSILDLG
                     NSPVAFKFEIENAKLYGIEGSIQQHYLKY"
     gene            4249..5826
                     /locus_tag="VXF95_001956"
     CDS             4249..5826
                     /locus_tag="VXF95_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082452.1"
                     /translation="MVKLNKVLKGSVAFLSASLLLAACGNNANSKPAEKTADGKTKIS
                     FLSTWQINDVRPPKDETLVGQWLEEQLGIDIDLVTIPGEGVSSKVNSLITSNQLPTVL
                     LTTGDKSDIAGINKLGKQGAFLDLSQHMDKLPNYKKYLEKNNALAQIEDDEKHIYAFT
                     KFFTDENIMYTTPILRKDLLVGSEFEDLSKIKTVDDYTKVLKYLTEKQGSPAFIQRNG
                     YEGFMKRVTPLWNLSHRTYYDYESDSYKHPVEQPQLKQFVEWLKELRKDNVLHPDWAV
                     MKDETWEGLLASNKGSFTVDRMNIIGDNNFDKSFDWQPLVYPEINGKRYLQPKTPYIS
                     DSGWVINANAPKEEIDKALEFFNFLYADENQEKLAIGFEGKTFTRENPNTQAGIKWLI
                     QIYGENAGNDKAELLFKHGNQAFTRVQTKLDIEAQPGTFPKVMYDQVDKIKKDLGGFR
                     PDTPVLSFTTEELDVLTKSEAGLNTFFDENIIKFIEGQRDMSEWDSFINEAKSKDLDK
                     VTKVYNDAYKRVKDRMK"
     gene            5886..>7297
                     /locus_tag="VXF95_001957"
     CDS             5886..>7297
                     /locus_tag="VXF95_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HEV1082453.1"
                     /translation="MYDVVIIGAGSSGALAAIASGRLGLKTCLIEKGSRIGGVPINTL
                     MGSFANLYFDDSGRVNASKIVGELIERIIKKGGTVFNSMEELMNVNDFYQITIPYQPE
                     VYESVLTDMLIESKVDILLNVEVNNIIYDSKNIKSLEILSNQEVKLIDSKVFIDATGN
                     ATIASASGADVYEKNSSYGCLMRVGGVDISKTIEHIEKTKQWNYIEGYNQWLEEVLAN
                     RKYRATGAVLKDPVSYDHAPMLSKDDHFMNDEKWNYIKERWEKFRFIYTLEVSLFRNE
                     LKKAVESGDFNFEIYHDDKSGVTMNGDGISYGSWGQNVALINVAKAFGFNPKYMEDES
                     HANILSRKYNLTFLSFLKKYVPGFENSFILDQGTRATNRSCRHIDNSSMMDEILDFPM
                     YTFKTMYSYQTPKEITYKSIVGGKLNNLFVIGKGAYQSESFRSQISCMLMGISSAAAA
                     KTIIEDKSNTLNINRDLFKS"
BASE COUNT         2514 a          975 c         1387 g         2421 t
ORIGIN      
        1 gtgtattgaa tctataacag tacgccttaa atgctaaaat atttctataa attaatttaa
       61 ctttcctgat agggctgttc atatcttatt tcaattcact atataaataa aattgtagta
      121 gatgttattg aattagtaaa aaaaataaaa aaacggaggt tttctgaatg gaaactaaaa
      181 aaattaaaaa tttaaaaggt caaataattg tttcctgcca agcgttagaa ggagagccac
      241 tttatactcc aaatggagga gtgatgccgt tattagcaaa agccgccttt caagcaggcg
      301 ctaaaggtat tcgtgctaat tctgtccgcg atatttcaga aataaaagaa gaagttgact
      361 taccaattat aggtatcata aaaagagatt acgatggctt tgaacctttt atttcagcaa
      421 ctatgaaaga gattgatgaa ttagttagtg aaggagtaga cattttagct ttggattgta
      481 ctaatcgttc aagaccaggt tatgataata ttactgactt tattcatgat attaaagtca
      541 agtatccaaa caaattatta atggctgata tttctacttt tgaagaaggg aaagtagctg
      601 ttgaatcggg agtagatttt gtgggtacga cattatctgg ttatacacca tatagcccta
      661 aaaaagataa tcctgatttt gagttagttg aaagattggt aaaagagctt gacgtaccag
      721 ttattgctga aggaagaata agtactccgg aacaagctag aaaaatgtta gatttaggtg
      781 cttacgcagt ggttgttgga ggagctatca ctcgtccttt ggaaatagcg aagaagttta
      841 ttgaggtagt ttagatgaat caagaaatat taaaaaagag taagattcaa ttgacagttg
      901 aacatattca aaaatattgg attttatatt taatgatgat tccagcaact gttctactaa
      961 ttttatttac gtatggacca atgtacggca ttattatggc ctttcaagac tttactgtct
     1021 tcaagggata tactggaagt ccatttgtcg gtttaaaaca ttttcaaaga ttgttctcag
     1081 atcctttgtt ttatagattg ttcaagaata cgttcatggt aggggtttta gactttttat
     1141 tctctttccc agctccgctt atttttgcac tcatattaaa cgaagtcaga aaagtaagat
     1201 ttaagagtgt agttcaatct attagttatc ttcctcattt tattccccta gtggttatgg
     1261 ttggtattat ttttgaacta tttggttcat atggtattat taacagttta ctttcatcac
     1321 ttggaatgga gccaataagt ttctttacaa aatctgaatg gttcttgcct ctctacattg
     1381 gttcaggagt atggaaaaca ataggttggg gttctatcat ttatatggga gcattaacca
     1441 atatagattc aactttatat gaagcagcag atatggacgg ggctaataga tggcacaaaa
     1501 tgtggcatgt aactctacca agtttaagac ctacagtagt tactttgttt atactaaatg
     1561 ctggtggtat catgcaagta ggatttgaaa aggtattctt gatgtctagt cctgcaacat
     1621 atgaagtatc tgatgtatta tctacttatg tttatagaca aggtatttta aattctgatt
     1681 tcagttactc agctgcagta ggattattta ataacatagt agctttgtta tttgttttat
     1741 tagctaataa gattgctaaa aaacttggcg aagaaggaat tgtataaggg gggtaaaatg
     1801 attttttcaa aaaatacaaa aaagagtaat agagacaaag aaaccttcgt tgattatctc
     1861 tttatattca ttttaataat aataacctta cttatgttgt atccattatg gtgggtagtg
     1921 atgacgtcac tttcagaacc agtttggcta tctaaaaacg ttgttaaatt atttccctta
     1981 aaaatagata ttactgcata taagtttatt tttggggatt ctaaactatg gcaagcatat
     2041 ggtaatagtg tattgtatgc tgcactatct acaattgtta gtgttgcggt atgtagtatg
     2101 tatgcctatc cacttacaat tcctgaaatt aggggtaaaa aattctggaa tactcttatt
     2161 ttgattccaa tgttctttag tggaggaatg atcccgcttt atatacaagt tgcaaacctc
     2221 ggtttattga atactgcttg ggctcttgtt ttacctagtg ctgtttctac atattatata
     2281 attttgttta gaacacagtt taaatcaatc ccaatggagc ttcgtgagtc tgctagaatt
     2341 gatggggcaa gtgaatttag aattttttgg aatttagtat taccattatc aaaagttatt
     2401 ttcatgatta tagcacttta ttgcatagtt ggttcatgga atagttttac tcctccatta
     2461 ctttatttga atgacgacac taagatgcct ttatctattt atttgagaaa tttagttgtt
     2521 acaaatacaa ctgatactgc tgaattatca ctttctgcag gtaatacata ttaccaacaa
     2581 attgctgctc aaggtggagg tattggtatg cgtattgcta ttaagatggg tactattgtt
     2641 gttagtgtta ttccaattat gatgatttat ccatttattc agaaacattt tgttaaggga
     2701 atcctgctag gttctgtgaa aggttaataa ggtaattatt ttgcaaaatt taaaaaaata
     2761 tcttttatta gatagcggtt tagtagttgg gtatacatta gaaaatgctc aattaaaatt
     2821 aaataagcta aaaaaagata ctgaaaacaa tccactattt ggtgaagagt attttgccga
     2881 aaatcctaaa ttatgggaag ttcgttttga taattcatat ccaaacgtta tctatgataa
     2941 agaattgaaa ttatatagat gttggtatca aacatttgtt agtgatgaag caagcgaaga
     3001 gactccttta gcagaacgtg gagagaagga atacattgtc aagtcatcta gaatgacagc
     3061 actttgctat gctgaaagta aagatggagt aaaatgggaa aaaccaaatc tcaatctagt
     3121 aaaatttaaa ggttcaaaag ataataatat tgttctgatg catgcacacg gtgcaggtat
     3181 catgctagat gaacaggagt tggatcctaa gaaacgatat aaattagttt caaaattaga
     3241 attttctccg aatcttcatt acatggttgt tgttttttca gaagacggta ttcattttga
     3301 cgaacctatt ccatggaaaa aatggaatcc tgcagcagat agtcataatt ttccatttag
     3361 agatccaaaa actggtaaat acgctgttat tacaagaacc tgggcaaata acgtacgtct
     3421 aagtgcaatt actttcagtg atgattttat taattggtca gaacctaaag aaatccttag
     3481 gggagatgga tttgaagatc aaatttattc tatgccagta atttcatacg cggatatcta
     3541 tttaggtttt gcttcaatgt accacgaagg cgacacttta aatgaaaact atgataaagt
     3601 agacttagaa ttgaaattct ctgctaattt ggaacaatgg gatagtgtat gtaagggcga
     3661 ctatctcatt gaaaggggag gtggagtata cccgcagaat gctgattttg atgctagttg
     3721 tattttcacg gctgctccaa taattgaaga tgataagatt tggttctact atatgggtgg
     3781 aaatggtaat cacattggct tccgagaaag ttcattagct agaggatata ttaagaaaga
     3841 ccaatttgct tattatacta ataagagaga aggaattcca gctaaaatat ctacagttag
     3901 cttccaaact tacgatgatg aaatttatat cttagctgat attcctgaaa atggttatat
     3961 taaagttgcg gtaggtacta aatacggtaa tgcttattca gattttggtc aggaagatat
     4021 ctctcttgtt caagtttccg atggtaagta taagttggaa tttaataaaa aatctatctt
     4081 agatttaggt aattctccag ttgcgttcaa atttgaaatc gagaatgcaa aattgtatgg
     4141 tattgaaggt agtattcagc aacactatct caaatattaa ccagaataat tcgttaacaa
     4201 ataatctcta tattagtgga gatagatata taaaatggag gtcttattat ggtaaagctt
     4261 aataaggtat taaaagggag tgttgcattc ctgagtgcaa gtttattgct agcagcttgt
     4321 ggcaataacg ctaattcaaa gcccgctgaa aaaacagctg atggtaaaac gaaaatttcg
     4381 tttctatcta catggcaaat taatgatgtt cgtccgccta aagatgaaac acttgttggt
     4441 caatggttag aagaacagct aggtattgat attgatcttg taactattcc tggcgaggga
     4501 gtaagttcta aagtaaattc tcttattact agtaaccagt taccgactgt tttgttgaca
     4561 acaggagata agagtgatat cgctggtatc aacaaacttg gtaaacaggg tgcattctta
     4621 gatttgtcac aacacatgga caaactacca aactataaga agtaccttga aaaaaataat
     4681 gcattagctc aaatagaaga tgatgaaaaa catatttatg ctttcacaaa attctttact
     4741 gatgagaata tcatgtatac tacaccaatt ctgagaaaag acttacttgt tggttcagaa
     4801 tttgaagatc tttcaaaaat taaaactgtt gatgactata caaaagtttt gaaatatttg
     4861 actgaaaaac aaggttctcc agcatttatt caacgtaatg gctatgaagg cttcatgaag
     4921 cgagttacac cattgtggaa tttaagccat cgtacatact atgactatga atcagattca
     4981 tataaacatc cagttgaaca acctcaattg aaacaattcg ttgaatggtt gaaagaatta
     5041 cgtaaagata acgtacttca ccctgactgg gcagttatga aagatgaaac ttgggaaggt
     5101 ctattggctt ctaacaaggg ttcattcact gttgaccgta tgaatatcat tggagataat
     5161 aactttgata aatcatttga ttggcagcca cttgtttatc cagaaattaa tggaaaacgt
     5221 tatttgcaac cgaaaacacc gtacatttct gattcaggtt gggtaatcaa tgccaatgca
     5281 ccaaaagaag aaattgataa agcgttagaa ttctttaatt tcttatacgc tgatgaaaat
     5341 caagaaaaac ttgctattgg atttgaaggt aaaacattta cacgtgaaaa ccctaatact
     5401 caagcaggta ttaaatggtt gattcaaatt tacggtgaaa atgctggaaa tgataaagca
     5461 gaactgctgt ttaaacatgg taaccaagca tttactcgcg ttcaaactaa attagatatt
     5521 gaggcacagc caggaacatt ccctaaagtt atgtatgatc aagtagataa aattaagaaa
     5581 gatttaggtg gttttagacc agatactccg gttctttcct ttacaactga agaattagat
     5641 gttttaacta aatctgaagc aggattaaat actttctttg atgaaaatat tattaaattc
     5701 attgaaggac aaagagatat gagtgagtgg gattcattta tcaatgaagc taaatctaaa
     5761 gacttggata aagttacaaa agtatataat gatgcctaca aacgtgtcaa agatagaatg
     5821 aaatagacta aatggtagct ctctggtttt tcagagagct actactgcct gagggggagt
     5881 aagctttgta tgatgtagta attataggtg caggaagttc gggcgcattg gctgcaattg
     5941 cttcggggcg tctagggtta aaaacttgtc taatagagaa gggaagtaga attggtggag
     6001 ttcctattaa tacactaatg gggtcatttg ctaatctata ttttgatgat tctggtagag
     6061 taaatgcaag taaaattgtt ggggaattaa tagaacgtat tatcaaaaaa ggtggtactg
     6121 tctttaactc tatggaagaa ttgatgaatg taaatgattt ttatcagatt acaattccct
     6181 atcaaccaga agtttatgaa tcggttttaa ctgatatgtt gattgagtct aaagttgata
     6241 ttttactaaa tgttgaagtt aataatatta tttatgatag taaaaatatt aaaagtcttg
     6301 aaattttaag taatcaggaa gttaaattga ttgattctaa agtttttatt gatgctacag
     6361 ggaatgcaac aattgcttct gctagtggag ctgatgttta tgaaaaaaat tcttcttacg
     6421 gttgtttaat gagagttgga ggagttgata tctcaaagac tatagaacat attgaaaaaa
     6481 caaagcagtg gaactatata gaaggatata atcagtggtt agaagaagta ttagcaaatc
     6541 gaaagtacag agccactgga gcagttttaa aagatccagt ttcttatgat catgccccta
     6601 tgctttcaaa agacgaccat tttatgaatg atgaaaaatg gaattacatt aaagaaagat
     6661 gggaaaaatt tagatttatt tacactttag aagtatcact atttaggaat gaattaaaaa
     6721 aagctgtaga atctggggat tttaattttg aaatttatca tgatgataaa tctggagtca
     6781 ctatgaatgg cgacggtata agctatggtt catggggtca aaatgtagca ttaattaatg
     6841 ttgcaaaagc atttggattc aatcccaaat atatggaaga tgaatcacat gctaatattc
     6901 tttctagaaa atataattta acatttttat cttttcttaa aaaatatgta ccaggttttg
     6961 aaaattcttt tatccttgat cagggaacta gagctactaa cagatcatgt aggcacattg
     7021 ataattcatc tatgatggac gaaattcttg attttccaat gtatacattt aagactatgt
     7081 atagctatca aactcctaaa gaaataacgt ataaatcaat tgtaggtgga aaattgaata
     7141 atttgtttgt aataggtaaa ggtgcttacc aatccgaaag ttttagatca caaattagtt
     7201 gtatgttaat ggggatatca tcagcagcag cggcaaaaac tattattgaa gataaaagca
     7261 atactctaaa cattaataga gatttgttta aatcgaa
//
LOCUS       DAVLMQ010000074         7157 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000074 DAVLMQ010000000
VERSION     DAVLMQ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.074"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..736
                     /locus_tag="VXF95_001958"
                     /pseudo
     CDS             1..736
                     /locus_tag="VXF95_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            822..1772
                     /locus_tag="VXF95_001959"
     CDS             822..1772
                     /locus_tag="VXF95_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1082454.1"
                     /translation="MGKKRWARNGSESNDASYAQVVSLYDDTSISVSNNETDKVLTGS
                     LYTETNEQGLTIPSSLLKNWNEQTGKNLTTNDLIGKSVSASIVESAAETSKIAQFQTK
                     IVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTEELQK
                     NKKYTVFSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRSKEIG
                     VMKAVGYQNRGVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSITKVFE
                     LNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVESLRYE"
     gene            1949..2956
                     /gene="gap"
                     /locus_tag="VXF95_001960"
     CDS             1949..2956
                     /gene="gap"
                     /locus_tag="VXF95_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HEV1082455.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(3023..3859)
                     /locus_tag="VXF95_001961"
     CDS             complement(3023..3859)
                     /locus_tag="VXF95_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HEV1082456.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYSQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLARCKLKTGRTHQIR
                     VHLSHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLEKLTFTTLSNTFEKELKK
                     NG"
     gene            3985..6180
                     /locus_tag="VXF95_001962"
     CDS             3985..6180
                     /locus_tag="VXF95_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HEV1082457.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVELTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMASQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEEIVNNGYR
                     IYTELDQNYQANMQVVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIASHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            6233..6385
                     /gene="rpmG"
                     /locus_tag="VXF95_001963"
     CDS             6233..6385
                     /gene="rpmG"
                     /locus_tag="VXF95_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1082458.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6395..6571
                     /gene="secE"
                     /locus_tag="VXF95_001964"
     CDS             6395..6571
                     /gene="secE"
                     /locus_tag="VXF95_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HEV1082459.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6626..>7157
                     /gene="nusG"
                     /locus_tag="VXF95_001965"
     CDS             6626..>7157
                     /gene="nusG"
                     /locus_tag="VXF95_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HEV1082460.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAE"
BASE COUNT         2252 a         1260 c         1537 g         2108 t
ORIGIN      
        1 tggttaaagc taaaagagaa aacaggagag ctaaaccacc aagtaaaagg aacaaaacca
       61 agaaaggttg atagagatag acttaaaaac tatcttactg acaatccaga cgcttatttg
      121 actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc gctcaaagct
      181 atgggctaca ctcgaaaaaa agaaccacac ctactatgaa caagacccag aaaaagtagc
      241 cttatttctt aaaaatttta atagtttaaa gcacctagca cctgtttaga ttgatgaaac
      301 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaagaag
      361 aggtaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
      421 tgagttaatc gctccaatga cttacgaaga gatgatgacg agcgactttt ttgaagcttg
      481 gtttcagaag tttctcttac caacattaac cacaccatcg gttattatta tggataatgc
      541 aagattccat agaatgggta agttagaact tttatgcgag gagtttgggc ataaactttt
      601 acctcttcct ccctactcac ctgagtacaa tcctattgag aaaacatggg ctcatatcaa
      661 aaagcacctc aaaaaggtat taccaagttg caataccttt tatgaggctc ttttgtcctg
      721 ctcttgtttc aattgactat agttcacgga tacagttggg aaagaagcta ttaaatattt
      781 ggagagtcct tttgggatga acatgtcaaa tattactata gatgggcaag aaaagatggg
      841 caagaaatgg atctgagtca aacgatgctt cttatgctca agtagtgagt ctttatgatg
      901 atacaagtat ctctgttagt aataatgaga cggacaaagt gttgactgga tccctctata
      961 ctgaaacaaa tgaacaggga ttaacgattc caagcagttt actaaaaaat tggaatgaac
     1021 agacaggaaa aaatttgaca actaatgatc ttattggcaa atcagtctca gccagcattg
     1081 tagaaagtgc tgccgaaact agtaagattg ctcaatttca aacgaagatt gtacgtgtaa
     1141 tcaatgatga agatgacatg gaggacagca acagtttcat gctgtctcat caaatggaaa
     1201 cgattttgaa agaggctgga tttacgaaag ctgtatctta ttttatcttg gaactcaaag
     1261 atccatcaca gacaaaagta gtaacagaag aattacagaa aaataagaag tatactgtgt
     1321 tttctcaaca gagagttctt gatattgtga ttacctttat tcgtgttatt cagggattat
     1381 tgattgtgct ttcatcacaa gctattgtgg tagcagcggt tatgattggt atcattattt
     1441 acatcaatat catgcaacgt tccaaggaaa taggtgtcat gaaagcagtt ggttatcaga
     1501 atcgtggtgt caaaggaatt tttatttacg aggctatctg gattgtaggc atcgccttgc
     1561 tgctggcatt tttggttgca caaggggtgg gaagtttggc gaatgcgatt gtaagtcact
     1621 tttacccatc catcactaag gtttttgaat taaatctttt atctgtttta ggaactctag
     1681 ttttcgctct attacttggt tatgtctcag cctacttccc ggcgcgtaag attagtaaaa
     1741 tggatcctgt agaatcgtta cgctatgaat aataagggat tccttgattt acagtcttaa
     1801 aaagaaactc acatagaaaa acaatggcca tacttgcaat tcaactcaaa tagttgtata
     1861 ataggtttgt tgaaaggtga tttgtagtga ttcaagttac tcttttcaca ataaaaattt
     1921 catgattttc ataaggagga aatcactaat ggtagttaaa gttggtatta acggtttcgg
     1981 acgtatcggt cgtcttgctt tccgtcgtat ccaaaacgta gaaggtgttg aagttacacg
     2041 catcaacgac cttacagatc cagttatgct tgcacacttg ttgaaatacg acacaactca
     2101 aggtcgtttc gacggtactg ttgaagttaa agaaggtgga ttcgaagtta acggtaaatt
     2161 cgttaaagtt tctgctgaac gtgatccaga gcaaatcgac tgggctactg acggtgtaga
     2221 aatcgttctt gaagctactg gtttctttgc taagaaagaa gcagctgaaa aacaccttaa
     2281 aggtggagct aaaaaagttg ttatcactgc tcctggtgga aacgacgtta aaacagttgt
     2341 attcaacact aaccacgacg ttcttgacgg tactgaaaca gttatctcag gtgcttcatg
     2401 tactacaaac tgcttggctc caatggctaa agctcttcaa gataactttg gtgttgttga
     2461 aggattgatg actactatcc acgcttacac tggtgaccaa atgatccttg acggaccaca
     2521 ccgtggtggt gaccttcgcc gtgctcgcgc tggtgctgca aacatcgttc ctaactcaac
     2581 tggtgctgct aaagctatcg gtcttgtaat cccagaattg aacggtaaac ttgacggatc
     2641 tgcacaacgc gttccaactc caactggatc agttactgaa ttggtagcag ttcttgaaaa
     2701 gaacgttact gttgatgaag tgaacgcagc tatgaaagca gcttcaaacg aatcatacgg
     2761 ttacacagaa gatccaatcg tatcttcaga tatcgtaggt atgtcttacg gttcattgtt
     2821 tgacgcaact caaactaaag ttcttgacgt tgacggtaaa caattggtta aagttgtatc
     2881 atggtacgac aacgaaatgt catacactgc acaacttgtt cgtactcttg aatacttcgc
     2941 aaaaattgct aaataattct tgagttgata gaaagcaagg ctttgtggtc ttgcttttta
     3001 tatggaaaaa tggatgacac gatcatccat tcttttttaa ttctttttca aatgtatttg
     3061 aaagggtagt gaaagttagc ttctctaaag taagtgggtg ggtaaaggaa agtcggaagg
     3121 catgaagcat aagccgactt gtctttgatt tactattata gagagggtcg cccaggatag
     3181 gaagattatg atgcgaaagg tgcacacgaa tctgatgggt tcgccctgtc tttagcttgc
     3241 aacgagccaa ggaagtcttg tttgagaatt gctttaacct gcttacatgc gtttcagcat
     3301 attgcccatt ttttgcatca actattcttt ttctacgatc atggcgatca cgtccaattt
     3361 tgtctctgaa aacaagttct tttctgttga tatttccatc aactagagcc caatattctc
     3421 tagaaatctc ttttttctcc aataagcgat tgagaatggg caggataaaa ggatttttgg
     3481 caaagagaac taagccactg gtttccatgt ccagacgatg aacgacatag caggtttggc
     3541 caacataggt actgacatgg ttaagaaggg caatttcgtt tggttgatta ccatgcgttt
     3601 tcatcccctc tggtttgttt acaataatca agtgttgatc ttgataaact tcctgcacta
     3661 agtctgggtt gccccaaggg atcgtctttt gggaataatc ttcctcgtca aaagtcaact
     3721 ggcaaacatc tccaggattt acgatttcgt tccagtggac ttcttcttga tttatcaaaa
     3781 tatgtttctt gattctcaaa aaatgacgga tttttctagg gatgaggagt tgttcctcaa
     3841 gtaattgctt taccgtcatt tgaggtagag aggcgggtaa tgtaaatgtg aattgcatac
     3901 agatattgta acaaaaaaag ccctatttgg ataggaaata gctaaattct tgtcttccta
     3961 tgatgaagat gataaaataa acgcatgaaa ttagataaat tatttgagaa atttctttct
     4021 ctttttaaaa aagaaacaag tgaactagag gactctgatt ctactatctt acgtcgctct
     4081 cgtagtgatc gaaaaaaatt agcccaagta ggtccgattc gaaaattctg gcgtcgttat
     4141 catctaacaa agattatcct tatactaggt ttgagtgcag gcttgctagt tggaatctat
     4201 ttgtttgctg tagccaagtc aaccaatgtc aatgatttgc aaaatgcctt gaaaactcga
     4261 actcttattt ttgaccgtga agaaaaagag gctggtgcct tgtctggtca aaagggaacc
     4321 tatgttgagc tgactgacat cagtaaaaac ttgcagaatg ctgttattgc gacagaagac
     4381 cgttctttct ataaaaatga cgggattaac tatggccgtt tcttcttggc tattgtcact
     4441 gctggccgtt caggtggtgg ctctaccatt acccaacagc tggctaaaaa cgcctattta
     4501 tcgcaggatc aaactgttga gagaaaagcg aaagaatttt tccttgcctt agaattaagc
     4561 aaaaaatata gtaaggagca aattctaacc atgtacctta acaacgctta ttttggaaat
     4621 ggtgtgtggg gtgtagaaga tgcgagtaag aaatactttg gagtttctgc atcagaagtg
     4681 agtctggatc aagctgcgac tctggcaggg atgctcaagg ggccggaact gtataatccc
     4741 ttgaattccg tagaagattc tactaatcgg cgcgatactg tcttgcagaa tatggttgca
     4801 gcaggatata ttgataaaaa ccaagaaacc gaagctgctg aagttgatat ggcttcgcaa
     4861 ttgcacgata agtatgaagg aaaaatctca gattaccgtt acccctctta ttttgatgcg
     4921 gtggttaatg aagctgtttc caagtataat ctaacagagg aagagattgt caataatggc
     4981 taccgcattt acacagagct ggaccaaaac taccaagcaa atatgcaggt tgtttatgaa
     5041 aacacatcgc tatttccgag ggcagaggat ggaacgtttg ctcaatcagg aagtgtagct
     5101 ctcgaaccga aaacaggggg agttcgtgga gttgtcggtc aagttgctga caatgataaa
     5161 actggattcc ggaatttcaa ctatgcaacc caatcaaagc gtagtcctgg ttctacaatt
     5221 aagcctttag ttgtttatac gccagcagtt gaagcaggct gggctttgaa taagcagttg
     5281 gataaccata ccatgcagta tgacagctat aaggttgata actatgcagg gatcaaaacg
     5341 agtcgagaag ttcctatgta tcaagccttg gcagaatcgc ttaatctacc tgctgttgcc
     5401 actgttaatg atttgggtgt cgacaaggct tttgaggcag gcgaaaaatt cggactcaac
     5461 atggaaaagg tcgaccgtgt tcttggtgtc gccttgggaa gcggtgttga aaccaaccct
     5521 cttcaaatgg ctcaagcata cgccgccttt gcaaatgaag gtttaatgcc tgaagctcat
     5581 tttattagta gaattgaaaa tgctagtgga caagttattg cgagtcataa aaattcacaa
     5641 aaacgggtga ttgataagtc tgtagctgac aagatgacca gtatgatgtt ggggactttc
     5701 accaacggta ccggtattag ttcatcgcct gcagactatg tcatggcagg gaaaactgga
     5761 acaactgaag cagttttcaa tccggagtac acaagtgacc agtgggtaat tggttatact
     5821 ccggatgtag tgattagcca ctggcttggc tttccgacca ctgatgaaaa ccattatcta
     5881 gctggctcta cttcaaacgg tgcagctcat gtctttagaa acattgccaa taccatttta
     5941 ccttatacgc caggaagtac ctttacggtt gaaaatgctt ataagcaaaa tggaattgca
     6001 ccagccaata caaaaagaca agtacaaacc aatgataata gccagacaga tgataatttg
     6061 tctgatattc gagggcgtgc gcaaagtcta gtagatgagg ctagccgggc tatctcagat
     6121 gcgaagatta aggaaaaggc tcaaacaata tgggattcga tagtcaatct atttcgctaa
     6181 gatgcttgtc aaagcctagc tttcttgtta taatggataa gatggaggcg ttatggcact
     6241 aaaaaaagca agcctagctt gtgcggtttg tggttcgaga aactattcaa tcaagatcag
     6301 cggaaacccc aagcctacac gactagaagt aaataaattt tgtaagcatt gtggcaagta
     6361 cactacacac agagaaacga gataggagag agcgatgcgt tttattggag atatttttag
     6421 acttcttaaa gacacaacat ggccaactcg caaggaaagc tggagagatt ttcgttctat
     6481 catggaatac acagctttct ttgtagtaat tatttacatt tttgaccagt tgattgtttc
     6541 aggtttgatt cgatttatta acatttttta gaagattagt ggagttaatt acactagaaa
     6601 tcttctattt atgaaaggaa atatcatgga tagttttgat aaagggtggt ttgttttaca
     6661 aacttattct ggttatgaaa ataaggtgaa agaaaatcta ttacaacgtg cacaaaccta
     6721 caatatgttg gataatattc tacgcgttga aattccaaca caaacagtgc aagttgaaaa
     6781 aaatggaaag agaaaagaag tagaagaaaa tcgctttcca ggttatgttc ttgtagaaat
     6841 ggtcatgaca gatgaagctt ggtttgttgt tcgaaacaca ccaaatgtta caggatttgt
     6901 cggatcacac gggaacagat caaaaccaac tccattattg gaacaagaaa ttcgcgacat
     6961 tttggtatct atgggacaaa ctgttcaaga atttgatttc gatgttgaga ttggtcaaac
     7021 tgtacgtatt attgatggtg cttttgcaga ctacactggt aagattacag aaattgataa
     7081 taacaaagtg aaaatgatta tctctatgtt tggtaatgac acagttgcag aagtaaatct
     7141 aaaccaaatc gcagaat
//
LOCUS       DAVLMQ010000075         7094 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000075 DAVLMQ010000000
VERSION     DAVLMQ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7094
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.075"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..664
                     /locus_tag="VXF95_001966"
     CDS             <1..664
                     /locus_tag="VXF95_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HEV1082461.1"
                     /translation="ADLTRNNIISCYKLKIMHWLILSISACILFSTIVNIRAPTFVQI
                     LFIFLGGFIIYKIHLKIKIFRYDLEHYLIIRESLLYVLHTNRLYTTYKDSTGQEKVIR
                     SAILEYELDRQKGHVLIKALIRGDEFSHKLKSLEDELCGVLELELEKKVLRPSVAEYH
                     FYYIKPKRLVLQSHNQRQEIDSLDIDLGYGVNYNPIKCPHILVSGGTGRGKSVFISFL
                     IA"
     gene            822..1211
                     /locus_tag="VXF95_001967"
     CDS             822..1211
                     /locus_tag="VXF95_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006268423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082462.1"
                     /translation="MQTFNYDDFKNEKGIVSFSEAEQIYSSLLNSSNQLDKEFQEEWT
                     TFVLLCVEYASARGKWLTLSREEKLANDESRTVTHNKVIYQLKILKGLASEQGNDVAW
                     FEQFNDDRKRIGDFACYVAYIYALNAR"
     gene            1378..2151
                     /locus_tag="VXF95_001968"
     CDS             1378..2151
                     /locus_tag="VXF95_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1082463.1"
                     /translation="MKTLLIGDLHLKSQLILPIVDKIIQTHNIKRIIFLGDYVDLHGQ
                     TNNIQLYAKDLTFLYSWKIDKEQNGIDVINLIGNHDAYYLLGEQAPFSIQNLEVFFAI
                     QQLLQDLNLQVAYQLDDYLVSHAGFNLIFDPKEWHFNLYTKEHEEELDILAYTIGPMR
                     GGKALGGSPLWAHFRELELLPNQDFPKQIVGHTPKESIDISKNVIGIDTFSLYIDKDN
                     KYQFIGNGDLLVYDQGHFEVISTDWATDKILKQLPQPQI"
     gene            2249..3031
                     /locus_tag="VXF95_001969"
     CDS             2249..3031
                     /locus_tag="VXF95_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004195527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HEV1082464.1"
                     /translation="MTSYNKKIVRTSSYIEIWEYEKPIFSKGKSILDTNTENKEKAKR
                     RTFDELTPLEQEQRLERMKKTRLEAKWNLLRLVDCNFDDTTSFLTLTTKENISDRNHF
                     KDLLKTFIKRFNYHIFNTKKSKLKYIAVLERQKRKAWHSHILLFSVPYIPHKQLLELW
                     GHGAVRINKVDVDSKENRGRYVTKYFEKGIGQELLENFGKQAYFSSRNLKKPDEDKFY
                     TYEDFNYDSSVVLYETEYTSKVYKDGQYFDNHVKYKKIRLDE"
     gene            3045..3248
                     /locus_tag="VXF95_001970"
     CDS             3045..3248
                     /locus_tag="VXF95_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HEV1082465.1"
                     /translation="MIATVTKNDLIALGFSEGTSKRIIRQGKELLITRGFTVYQNKRI
                     GTIPATIATELLGFDVQNSTLKE"
     gene            3252..4385
                     /locus_tag="VXF95_001971"
     CDS             3252..4385
                     /locus_tag="VXF95_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1082466.1"
                     /translation="MAIRKGKDGNWVVDISNGFDPITLKQRRLVRKGYKTKKEAIEAE
                     HYLRSVELKERFYGAKITISILYELLKEEDSINHRKASYINTQDNNYNKHIKDYFSMV
                     DNVGKLTYEDIYQFREHLRQKVAKNSDKPLSTNTINKIMILLKKIFDVGLRKGYYSSN
                     PAKLIKKLPIEKTKMQFWTVKEFQKFLTLFEPEEYNIKLLFTVLFFTGLRLGEALALT
                     WQDIDFSSNTIHITKSVYVNKGVTHISTTKTKAGTRRIVINKKLSQELQDWEKRQKHL
                     LEQFTNNSLTLQVFQNSPITITKNAIEKQYKKIIERDSTLKKIRIHDFRHSHASLLIN
                     QGEDYLVVKERLGHASITTTIDTYSHLYPSKQKDLADKLDDLL"
     gene            4426..4863
                     /locus_tag="VXF95_001972"
     CDS             4426..4863
                     /locus_tag="VXF95_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HEV1082467.1"
                     /translation="MDTSQVIKAHEVAKKAHFGQIDRAGIDYIKHPETVASFVATDEE
                     KAVAYLHDVIEDTSLTLLDLKKEGFSKNIIEAVDILTKKKGQDYQSYLNLVKKNELAR
                     VVKLADLRHNSDLTRLPLITEKDLERNKKYSSAIRFLRAKKKS"
     gene            5079..5315
                     /locus_tag="VXF95_001973"
     CDS             5079..5315
                     /locus_tag="VXF95_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001058278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HEV1082468.1"
                     /translation="MNNVVTTQISIQLSQELNSLLNAIVEENNTTKTDFIRQAVIEKI
                     EDMYDIKVADEAYKKWVECGKKAISHEEMMRRYG"
     gene            5308..6039
                     /locus_tag="VXF95_001974"
     CDS             5308..6039
                     /locus_tag="VXF95_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HEV1082469.1"
                     /translation="MAKLYAISDIHGYLDEFRDALNKVNLNDKDNRLFLLGDYLDNGL
                     QSFQVISKIIELEEVYPNQIITLLGNHEEWFYDWLILDKPTASAFPETIKSFFSPEEL
                     NYIFKSNANNFETGVRNEIKNNIKFNPFINWFKKRYRDKRYYETDTQIFVHAGIDEEA
                     GKLWKELTSSEIFTNKFPITTGRFHKAIISGHIASWEVAKDRRYLGKIYYDSKSHYFI
                     DGDVTNSKTIPILCYDTITQKYHFL"
     gene            complement(6150..6233)
                     /locus_tag="VXF95_001975"
     tRNA            complement(6150..6233)
                     /locus_tag="VXF95_001975"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6197..6199),aa:Leu,seq:caa)
     gene            complement(6243..6314)
                     /locus_tag="VXF95_001976"
     tRNA            complement(6243..6314)
                     /locus_tag="VXF95_001976"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6280..6282),aa:Gln,seq:ttg)
     gene            complement(6325..6397)
                     /locus_tag="VXF95_001977"
     tRNA            complement(6325..6397)
                     /locus_tag="VXF95_001977"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6362..6364),aa:His,seq:gtg)
     gene            complement(6412..6482)
                     /locus_tag="VXF95_001978"
     tRNA            complement(6412..6482)
                     /locus_tag="VXF95_001978"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6448..6450),aa:Trp,seq:cca)
     gene            complement(6487..6567)
                     /locus_tag="VXF95_001979"
     tRNA            complement(6487..6567)
                     /locus_tag="VXF95_001979"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6531..6533),aa:Tyr,seq:gta)
     gene            complement(6580..6652)
                     /locus_tag="VXF95_001980"
     tRNA            complement(6580..6652)
                     /locus_tag="VXF95_001980"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6617..6619),aa:Phe,seq:gaa)
     gene            complement(6656..6729)
                     /locus_tag="VXF95_001981"
     tRNA            complement(6656..6729)
                     /locus_tag="VXF95_001981"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6693..6695),aa:Met,seq:cat)
     gene            complement(6740..6829)
                     /locus_tag="VXF95_001982"
     tRNA            complement(6740..6829)
                     /locus_tag="VXF95_001982"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6791..6793),aa:Ser,seq:tga)
     gene            complement(6912..6985)
                     /locus_tag="VXF95_001983"
     tRNA            complement(6912..6985)
                     /locus_tag="VXF95_001983"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(6949..6951),aa:Ile,seq:gat)
     gene            complement(7020..7090)
                     /locus_tag="VXF95_001984"
     tRNA            complement(7020..7090)
                     /locus_tag="VXF95_001984"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7056..7058),aa:Gly,seq:tcc)
BASE COUNT         2585 a         1233 c         1234 g         2042 t
ORIGIN      
        1 tgctgattta acaagaaaca atataatttc ctgttataag ctaaaaataa tgcactggct
       61 gatactaagt atctctgcct gcattctatt ttctactatt gttaatatta gggctccaac
      121 ttttgttcaa attctcttca tatttttagg tggatttatt atctataaaa ttcatctgaa
      181 aataaaaatt tttcgatatg acttagagca ttaccttatt atacgtgaga gcttacttta
      241 tgtactccac acaaatagac tttatactac atataaagat agtactggac aagaaaaagt
      301 tattagaagt gcaatcttag aatatgaatt agatagacag aaaggtcatg tacttatcaa
      361 ggctcttata agaggggacg agtttagcca caaacttaaa tctcttgaag atgaactttg
      421 tggcgtgctt gaactagagc ttgagaaaaa ggttcttcgg cctagtgttg cagagtatca
      481 tttctattac ataaaaccaa aaaggttagt tctacaatct cacaaccaaa gacaagagat
      541 agatagcctt gatatagatt taggatatgg tgtaaattat aacccaatca aatgcccaca
      601 tattttagta tcaggaggga cagggagagg aaagtctgtc ttcatatctt tcctgatcgc
      661 ctagtgcttc tgttcaagag atggcgaaca acaaaacttg tcctgttact cttaaagatt
      721 taaatgtagg gcaattcaat ggaaacttgt ggttcgcttg ttctgatgtt ttacctgtaa
      781 caaaatagct aagattagat aatatataaa ggagttttac aatgcaaact tttaactacg
      841 atgattttaa gaatgaaaag gggattgttt cattttctga agcagaacaa atctattcta
      901 gtctccttaa ttcctccaat caacttgata aagaatttca agaagaatgg acaacatttg
      961 tacttctatg cgtagagtat gcctctgcac gtggtaaatg gctcacactc tcaagagaag
     1021 agaaacttgc caatgatgaa tctagaactg ttactcacaa taaagttatt tatcaactaa
     1081 agattttaaa aggtttagca agtgaacagg gcaatgatgt tgcttggttt gaacaattta
     1141 acgatgacag aaaacgtatt ggcgactttg cttgctatgt agcttatatc tatgccttaa
     1201 atgctcgata gacaattaga ggatattatg gctatatatt actctatttc tgatattcat
     1261 ggaaattatt aaataacatc ttaagaataa ttaattcttt ttatctatca ccgaaacaat
     1321 gtgctataac ttaattcgat tcttagacta atatcaaaaa taaagagggg aatatatatg
     1381 aagacgttat taattggtga tttacactta aaatctcaac tgattttacc cattgttgac
     1441 aaaattatcc aaacacataa tattaagaga atcatttttc ttggtgacta cgttgattta
     1501 catggtcaaa ctaacaatat ccaactttat gccaaagacc tcactttttt atactcttgg
     1561 aaaatagata aagagcaaaa tggaatagat gtaattaatc ttataggtaa tcatgatgct
     1621 tattatttac tgggagaaca agctcctttc tcaattcaaa atctagaggt ctttttcgca
     1681 attcaacaat tattacaaga tttgaattta caagtagctt atcaactaga tgattattta
     1741 gttagccatg ctggtttcaa tctgatattt gacccaaaag aatggcattt taacctctat
     1801 accaaagagc atgaagaaga attagatatt ctagcttata caataggacc aatgcgtggt
     1861 gggaaagctc ttgggggttc tcctttatgg gcacatttta gagaattaga actgcttccc
     1921 aaccaagact ttcctaaaca aattgttgga cataccccta aagaatctat tgatatttct
     1981 aaaaatgtta ttggtataga tactttttca ttatatattg acaaagataa taaatatcaa
     2041 tttattggta acggagattt gctcgtttat gaccaaggac attttgaggt catttcaaca
     2101 gactgggcaa cagacaaaat attaaaacaa ttaccacaac cacaaattta atagctactt
     2161 ctcatcatgt acctaagcaa aactgccgac aagcagtcag caagctggaa gtgtgtttag
     2221 cggagcggtg cttaggatca catgatatat gacctcatat aataaaaaaa tagtccgcac
     2281 ttcttcctat attgaaattt gggaatatga aaagccaata ttttcaaaag gaaaatctat
     2341 tttagatact aatactgaaa acaaggaaaa agcaaaacgc agaacatttg atgaactaac
     2401 acccctagaa caagaacaac gtcttgaacg tatgaagaag actcgcttag aagccaagtg
     2461 gaacttactc cgtctagttg attgtaattt tgatgataca acttcttttc ttacattgac
     2521 cactaaggaa aatatcagcg atagaaacca cttcaaagac ttactcaaaa catttattaa
     2581 acgctttaac tatcacattt ttaataccaa gaaaagtaaa ttaaaatata tagcagtatt
     2641 agagaggcaa aaacgtaaag catggcatag tcatattttg ctattcagtg ttccctatat
     2701 tccacataag caattattag aactttgggg gcatggagca gtacggataa ataaagttga
     2761 cgttgacagc aaagaaaatc gcggtcgata tgtcacaaag tattttgaaa aaggtattgg
     2821 acaagaattg ttggaaaact tcggaaagca agcatatttt tcatcacgca acttgaaaaa
     2881 gcctgatgaa gataaatttt acacttatga agattttaac tatgatagtt cagtcgtact
     2941 atatgaaacg gaatacacta gtaaggtcta taaagacggt cagtatttcg ataatcatgt
     3001 aaagtacaag aaaataagac tagatgaata aaggagtaag tcacatgata gcaactgtta
     3061 ctaagaatga cctaattgcc ctcggtttct ctgaaggaac atctaaacgt attatccgcc
     3121 aagggaaaga gctacttata acccgaggct ttacagtcta tcagaacaag cgaattggta
     3181 ctatacctgc tactattgct accgaattac tcggttttga tgttcaaaac agtaccctca
     3241 aggagtaaaa tatggcaatt agaaaaggta aagacggtaa ttgggtagtt gatattagca
     3301 acggttttga cccaataaca ctaaagcaac gtagacttgt cagaaagggc tataagacga
     3361 aaaaagaagc tattgaagca gaacactact tacgaagtgt agagttaaaa gaacgcttct
     3421 atggggctaa aataactatc tccatactat atgaactact taaggaagaa gatagcataa
     3481 atcatcgaaa agcaagctat atcaatacac aagataataa ttacaacaaa cacatcaaag
     3541 attatttttc tatggtcgat aatgtcggaa aactaaccta tgaagacatc taccaattta
     3601 gagaacatct taggcaaaaa gtagctaaaa attctgataa accgttaagc acaaatacta
     3661 ttaacaaaat catgatttta ctcaaaaaaa tttttgatgt tggtttgcga aaaggctatt
     3721 actcctccaa tccagcaaaa ttgataaaaa agttgccaat tgaaaaaaca aaaatgcaat
     3781 tttggacagt caaagaattt cagaagtttt tgacactatt tgaacccgaa gaatacaata
     3841 tcaaactact ctttactgtt ctattcttta caggattaag acttggggaa gctcttgccc
     3901 taacatggca agacatcgac ttttcaagta atacaattca tatcacgaaa tctgtctatg
     3961 ttaataaagg agtaactcat atcagcacaa caaaaactaa agcaggaaca agaagaattg
     4021 ttatcaataa aaaattaagc caagaattac aagattggga aaagcgacaa aaacatctat
     4081 tagagcaatt taccaacaat agcctaacat tacaagtgtt tcaaaatagt cctatcacaa
     4141 ttacgaaaaa tgctattgaa aagcagtaca agaaaatcat tgaacgtgat agcacactaa
     4201 aaaagatacg catacacgat tttaggcact cacacgcttc cctgctgatt aaccaagggg
     4261 aagattatct agttgtaaaa gagcgactag gacatgcttc tataacaacc acgattgata
     4321 cctactctca cttgtaccca agtaagcaaa aggatttagc tgataaacta gatgatttac
     4381 tataaagtaa ttgagtttta taaatggaaa gtttataatt aaatcatgga tacatcacaa
     4441 gtaataaaag cacatgaagt agctaaaaaa gcacactttg gacaaattga tagagcagga
     4501 attgactaca ttaaacaccc tgaaacagta gctagttttg tcgcaactga tgaagagaaa
     4561 gctgtcgcct atctacatga tgtaattgaa gatacttcac taaccctact agacctaaaa
     4621 aaggaaggtt tttcaaaaaa cattatagaa gccgtcgata tactcacaaa gaaaaaagga
     4681 caagattatc aatcttatct caatctagta aagaaaaatg aactcgctag agttgtaaag
     4741 ttggcggatt tacggcataa ttcagattta acaagactac cattaattac tgaaaaagac
     4801 ttagagagaa ataagaaata cagttctgct attagatttt taagagcaaa gaaaaaaagt
     4861 tagtaactaa actataaaat tttataaaga gaaaacaaaa gacaaggctt ataaactttg
     4921 tctttattac tatactggcg gtcggtctcg aactggcaca tccttgcaga tactacaatt
     4981 ttattaaaat aaataactat aaaaagtgaa attttttatt gagaaacttt tagactagga
     5041 gtataatgta tctaaaataa ctattaggtg gctgttatat gaataatgtt gttactacac
     5101 aaatttctat tcaacttagt caagagttaa attctttatt aaatgctatt gttgaagaaa
     5161 ataatacaac aaagactgac tttattagac aagctgttat agagaaaatt gaagatatgt
     5221 atgatattaa ggtcgctgat gaagcttata aaaaatgggt tgaatgtggc aaaaaagcta
     5281 tctcacatga agaaatgatg agacgctatg gctaaattat acgcaatatc tgatatacat
     5341 ggatacttgg atgaattcag agacgctctc aataaagtaa atttaaacga taaagataat
     5401 cgcctatttt tactaggaga ttatcttgat aatggacttc aatcttttca agtcatttcc
     5461 aaaataatcg aacttgagga agtttatcct aatcaaatta ttactcttct agggaatcat
     5521 gaagaatggt tttatgattg gttgatttta gataagccta ctgcttcagc atttccagaa
     5581 acaataaaaa gcttcttctc tccagaggaa ttgaactata tttttaaatc gaatgctaac
     5641 aactttgaaa caggtgttag aaatgaaatt aaaaataata tcaaattcaa tccatttata
     5701 aactggttta aaaaacgata tagggataaa cgctattatg aaactgatac ccaaattttt
     5761 gttcatgctg gcattgatga agaagccgga aagctttgga aagaactaac gagttcagag
     5821 atatttacaa acaaatttcc tattaccact ggtagatttc ataaagctat tatttcgggc
     5881 catattgctt cttgggaagt agctaaagat agaagatacc tgggtaagat ttactatgat
     5941 agtaaaagtc attattttat tgatggagat gtaacgaata gcaaaacaat acctattctt
     6001 tgctatgata caattaccca aaaatatcac tttctataac ttttaatcat gtgcttttat
     6061 atgaaattag taattattag taacaattcc aagaaatttc ttatgacata acaaaaagac
     6121 aaggcttaga aaccttgtct tttcaactat accggcggcc ggggtcgaac cggcacgtcc
     6181 ttgcggacac tggattttga gtccagcgcg tctgccaatt ccgccacgcc ggcaaatagt
     6241 aactggggta gctggattcg aaccaacgca tgagggagtc aaagtccctt gccttaccgc
     6301 ttggctatac cccaatataa aataggcgag tgatggggat cgaacccacg catgccagag
     6361 ccacaatctg gtgtgttaac cacttcacca cacccgccat aattctatta acacgggcag
     6421 taggaattga acccacactg aaggttttgg agaccttagt tctaccttta aactatgccc
     6481 gtaaaatgga aggggaggga ttcgaacccc cgaacccgaa ggagcggatt tacagtccgc
     6541 cgcgtttagc ctcttcgcta cccttccaaa atatataaat ggcgcgagac ggaatcgaac
     6601 cgccgacaca tggagcttca atccattgct ctaccaactg agctaccgag ccttattgcg
     6661 ggagcaggat ttgaacctac gaccttcggg ttatgagccc gacgagctac cgagctgctc
     6721 catcccgcgt taatataaaa ggaggatgtg ggattcgaac ccacgcacgc ttttacacgc
     6781 ctgacggttt tcaagaccgt tcccttcagc cggacttggg taatcctcca aaatagttta
     6841 tacgggaaca agcccgtgtc ctcttagtga acagataata ttccaatccc ctagtaatgg
     6901 actaaacact atgggcacga gtggactcga accaccgacc tcacgcttat caggcgtgcg
     6961 ctctaaccac ctgagctacg cgcccaagtc aaaaacttgg tacaaagaac aaagttcaaa
     7021 gcgggtgacg agaatcgaac tcgcgacaac agcttggaag gctgtagttt taccactaaa
     7081 ctacacccgc taaa
//
LOCUS       DAVLMQ010000076         6963 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000076 DAVLMQ010000000
VERSION     DAVLMQ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6963)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6963)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6963
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.076"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            99..6533
                     /locus_tag="VXF95_001985"
     CDS             99..6533
                     /locus_tag="VXF95_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HEV1082470.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALNISDKEKV
                     VLDKETENKEKHEDIHNAIETSQDFKEKKTAVIEGKEVVSKNPVTDNNTSNEEARVKE
                     DSNQSQGDHTDSFVNKNTENPKKEDKVVYIAEFKDKESGEKAIKQLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPDKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKFREVDDFTSETGKRIEEYDYKYDDKGNIIA
                     YDDGSALQYETEKLDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNSYKSIE
                     IKATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDDRIKAETKIRMPEKNKE
                     TKAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKG
                     YALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRST
                     QAVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDK
                     SNVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNW
                     ELRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMD
                     GNVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKR
                     NNGFDGEIQEQHIYINGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDT
                     GEVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKK
                     DAGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDL
                     QREDHSQKSDSTKDVTATVLDKNNISSKSTTNNLNKLPKTGTASGAQTLLAAGIMFIV
                     GIFLGLKKKNQD"
BASE COUNT         2732 a          947 c         1356 g         1928 t
ORIGIN      
        1 tttcctagat aatacttagt aaaacttttt ataacaaagg ctagcaaagt taaagtttat
       61 tatctattgg aagttaaata aatatgtaag gaattaaaat gaaaaaaagt acagtattgt
      121 cattaaccac agctgcagtt attttagcag cctatgcccc taatgaggta gtcttagcag
      181 acacatctag ctctgaagat gctttaaaca tctctgataa agaaaaagta gtattagata
      241 aggaaacaga aaataaagag aaacatgaag atattcataa tgctatagaa acttcacagg
      301 attttaaaga gaagaaaaca gcagtcattg agggaaaaga agttgttagt aaaaatcctg
      361 tgacagacaa taacactagc aatgaagaag caagagtcaa agaagattcc aatcaatccc
      421 aaggagatca tacggactca tttgtgaata aaaacacaga aaatcccaaa aaagaagata
      481 aagttgtcta tattgctgaa tttaaagata aagaatctgg agaaaaagca atcaagcaac
      541 tatccaatct taagaataca aaagttttat atacttatga tagaattttt aacggtagtg
      601 ccatagaaac aactccagat aacttggaca aaattaaaca aatagaaggt atttcatcgg
      661 ttgaaagggc acaaaaagtc caacccatga tgaatcatgc cagaaaggaa attggagttg
      721 aggaagctat tgattaccta aagtctatca atgctccgtt tgggaaaaat tttgatggta
      781 gaggtatggt catttcaaat atcgatactg gaacagatta tagacataag gctatgagaa
      841 tcgatgatga tgccaaagcc tcaatgagat ttaaaaaaga agacttaaaa ggaactgata
      901 aaaattattg gttgagtgat aaaatccctc atgcgttcaa ttattataat ggtggcaaaa
      961 tcactgtaga aaaatatgat gatggaaggg attattttga cccacatggg atgcatattg
     1021 cagggattct tgctggaaat gatactgaac aagatatcaa aaactttaac ggcatagatg
     1081 gaattgcacc taatgcacaa attttctctt acaaaatgta ttctgacgca ggatctgggt
     1141 ttgcgggtga tgaaacaatg tttcatgcta ttgaagattc tatcaaacac aacgttgatg
     1201 ttgtttcggt atcatctggt tttacaggaa caggtcttgt aggtgagaaa tattggcaag
     1261 ctattcgggc attaagaaaa gcaggcattc caatggttgt cgctacgggt aactatgcga
     1321 cttctgcttc aagttcttca tgggatttag tagcaaataa tcatctgaaa atgaccgaca
     1381 ctggaaatgt aacacgaact gcagcacatg aagatgcgat agcggtcgct tctgctaaaa
     1441 atcaaacagt tgagtttgat aaagttaaca taggtggaga aagttttaaa tacagaaata
     1501 taggggcctt tttcgataag aataaaatca caacaaatga agatggaaca aaagctccta
     1561 gtaaattaaa atttgtatat ataggcaagg ggcaagacca agatttgata ggtttggatc
     1621 ttaggggcaa aattgcagta atggatagaa tttatacaaa ggatttaaaa aatgctttta
     1681 aaaaagctat ggataagggt gcacgcgcca ttatggttgt aaatactgta aattactaca
     1741 atagagataa ttggacagag cttccagcta tgggatatga agcggatgaa ggtactaaaa
     1801 gtcaagtgtt ttcaatttca ggagatgatg gtgtaaagct atggaacatg attaatcctg
     1861 ataaaaaaac tgaagtcaaa agaaataata aagaagattt taaagataaa ttggagcaat
     1921 actatccaat tgatatggaa agttttaatt ccaacaaacc gaatgtaggt gacgaaaaag
     1981 agattgactt taagtttgca cctgacacag acaaagaact ctataaagaa gatatcatcg
     2041 ttccagcagg atctacatct tgggggccaa gaatagattt acttttaaaa cccgatgttt
     2101 cagcacctgg taaaaatatt aaatccacgc ttaatgttat taatggcaaa tcaacttatg
     2161 gctatatgtc aggaactagt atggcgactc caatcgtggc agcttctact gttttgatta
     2221 gaccgaaatt aaaggaaatg cttgaaagac ctgtattgaa aaatcttaag ggagatgaca
     2281 aaatagatct tacaagtctt acaaaaattg ctctacaaaa tactgcgcga cctatgatgg
     2341 atgcaacttc ttggaaagaa aaaagtcaat actttgcatc acctagacaa cagggagcag
     2401 gcctaattaa tgtggccaat gctttgagaa atgaagttgt agcaactttc aaaaacacgg
     2461 attctaaagg tttggtaaac tcatatggtt ccatttctct taaagaaata aaaggtgata
     2521 aaaaatactt tacaatcaag cttcacaata catcaaacag acctttgact tttaaagttt
     2581 cagcatcagc gataactaca gattctttaa ctgacagatt aaaacttgat gaaacatata
     2641 aagatgaaaa atctccagat ggtaagcaaa ttgttccaga aattcaccca gaaaaagtca
     2701 aaggagcaaa tatcacattt gagcatgata ctttcactat aggcgcaaat tctagctttg
     2761 atttgaatgc ggttataaat gttggagagg ccaaaaacaa aaataaattt gtagaatcat
     2821 ttattcattt tgagtcagtg gaagaaatgg aagctctaaa ctccaacggg aagaaaataa
     2881 acttccaacc ttctttgtcg atgcctctaa tgggatttgc tgggaattgg aaccacgaac
     2941 caatccttga taaatgggct tgggaagaag ggtcaagatc aaaaacactg ggaggttatg
     3001 atgatgatgg taaaccgaaa attccaggaa ccttaaataa gggaattggt ggagaacatg
     3061 gtatagataa atttaatcca gcaggagtta tacaaaatag aaaagataaa aatacaacat
     3121 ccctggatca aaatccagaa ttatttgctt tcaataacca agggatcaac gctccatcat
     3181 caagtggttc taagattgct aacatttatc ctttagattc aaatggaaat cctcaagatg
     3241 ctcaacttga aagaggatta acaccttctc cacttgtatt aagaagtgca gaagaaggat
     3301 tgatttcaat agtaaataca aataaagagg gagaaaatca aagagactta aaagtcattt
     3361 cgagagaaca ctttattaga ggaattttaa attctaaaag caatgatgca aagggaatca
     3421 aatcatctaa actaaaagtt tggggtgact tgaagtggga tggactcatc tataatccta
     3481 gaggtagaga agaaaatgca ccagaaagta aggataatca agatcctgct actaagataa
     3541 gaggtcaatt tgaaccgatt gcggaaggtc aatatttcta taaatttaaa tatagattaa
     3601 ctaaagatta cccatggcag gtttcctata ttcctgtaaa aattgataac accgccccta
     3661 agattgtttc ggttgatttt tcaaatcctg aaaaaattaa gttgattaca aaggatactt
     3721 atcataaggt aaaagatcag tataagaatg aaacgctatt tgcgagagac caaaaagaac
     3781 atcctgaaaa atttgacgag attgcgaacg aagtttggta tgctggcgcc gctcttgtta
     3841 atgaagatgg agaggttgaa aaaaatcttg aagtaactta cgcaggtgag ggtcaaggaa
     3901 gaaatagaaa acttgacaaa gacggaaata ccatttatga aattaaaggt gcgggagatt
     3961 taaggggaaa aatcattgaa gtcattgcat tagatggttc tagcaatttc acaaagattc
     4021 atagaattaa atttgctaat caggctgatg aaaaggggat gatttcctat tatctagtag
     4081 atcctgatca agattcatct aaatatcaaa agcttggcga gattgcagaa tctaaattta
     4141 aaaatttagg aaatggaaaa gagggtagtc taaaaaaaga tacaactggg gtagaacatc
     4201 atcatcaaga aaatgaagag tctattaaag aaaaatctag ttttactatt gatagaaata
     4261 tttcaacaat tagagacttt gaaaataaag acttaaagaa actcattaaa aagaaattta
     4321 gagaagttga tgattttaca agtgaaactg gtaagagaat agaggaatac gattataaat
     4381 acgatgataa gggaaatatt attgcttatg acgatggtag tgccttacaa tatgaaactg
     4441 aaaaacttga cgaaataaaa tcaaaaattt atggtgttct aagcccatct aaagatggac
     4501 actttgaaat tcttggaaag ataagcaatg tttctaaaaa tgccaaggta tattatggaa
     4561 atagctataa atcgatagaa atcaaagcga ctaagtatga ttcacattca aaaacgatga
     4621 tatttgattt atacgctaat attaatgata ttgtagatgg attagctttt gctggagata
     4681 tgagattatt tgttaaagat gatgatcgaa taaaagctga aactaagatt agaatgcctg
     4741 aaaaaaataa ggaaactaaa gcagaatatc cctatgtatc aagttatggg aatgtaatcg
     4801 aattaggaga aggagatctt tcaaagaaca aaccagacaa tttaactaaa atggaatctg
     4861 gtaaaatcta ttctgattca gaaaaacaac aatatctgtt aaaggataac atcattctaa
     4921 gaaaaggcta tgcactaaaa gtgactacct ataatcctgg aaaaacggat atgttagaag
     4981 gaaatggagt ctatagcaag gaagatatag caaaaataca aaaggccaat cctaatctaa
     5041 gagtcctttc agaaacaaca atttatgctg atagtagaaa tgttgaagat ggaagaagta
     5101 cccaagctgt attaatgtcg gctttggacg gctttaacat tataaggtat caagtgttta
     5161 catttaaaat gaacgataaa ggggaagcta tcgataaaga cggaaatctt gtgacagatt
     5221 cttctaaact tgtattattt ggtaaggatg ataaagaata cactggagag gataagtcca
     5281 atgtagaagc tataaaagaa gatggttcca tgttatttat tgataccaaa ccagtaaacc
     5341 tttcaatgga taagaactac tttaatccat ctaaatctaa taaaatttat gtacgaaatc
     5401 cagaatttta tttaagaggt aagatttctg ataagggtgg ttttaactgg gaattgagag
     5461 ttaatgaatc ggttgtagat aattatttaa tctacggaga tttacacatt gataacacta
     5521 gagattttaa tattaagttg aatgttaaag acggtgacat catggactgg ggaatgaaag
     5581 actataaagc aaacggattt ccagataagg taacagatat ggatggaaat gtttatcttc
     5641 aaactggcta tagcgatttg aatgctaaag cagttggagt ccactatcag tttttatatg
     5701 ataatgttaa acccgaagta aacattgatc ctaagggaaa tactagtatc gaatatgctg
     5761 atggaaaatc tgtagtcttt aacatcaatg ataaaagaaa taatggattc gatggtgaga
     5821 ttcaagaaca acatatttat ataaatggaa aagaatatac atcgtttgat gatattaaac
     5881 aaataacaga caagacacta aacattaaga ttgttgtaaa agattttgca agaaatacaa
     5941 ccgtaaaaga attcatttta aataaagata cgggagaggt cagtgaatta aaacctcata
     6001 gggtaactgt gaccattcaa aatggaaaag aaatgagttc aacgatagtg tcggaagaag
     6061 attttatttt acctgtttat aagggtgaat tagaaaaagg ataccaattt gatggttggg
     6121 aaatttctgg tttcgaaggt aaaaaagacg ctggctatgt tattaatcta tcaaaagata
     6181 cctttataaa acctgtattc aagaaaatag aggagaaaaa ggaggaagaa aataaaccta
     6241 cttttgatgt atcgaaaaag aaagataacc cacaagtaaa ccatagtcaa ttaaatgaaa
     6301 gtcacagaaa agaggattta caaagagaag atcattcaca aaaatctgat tcaactaagg
     6361 atgttacagc tacagttctt gataaaaaca atatcagtag taaatcaact actaacaatc
     6421 ttaataagtt gccaaaaact ggaacagcaa gcggagccca gacactatta gctgccggaa
     6481 taatgtttat agtaggaatt tttcttggat tgaagaaaaa aaatcaagat taagataaaa
     6541 gctatagaaa aaaatggttt atgtactgag attagatagt gaggtgatga catagttttg
     6601 tgaaaacagc catttataac tcaattattt agtttacttc actattgata ctatttggag
     6661 ttattaatgg acttagttta gataactaat gaattgattg aaagggttag tattgacaat
     6721 attggtcata ttgattagaa aatagagtct atcaaaattt aaaggctaat agaggtgatg
     6781 agacaatttc aaggaattaa gtagcgtttg gttgcttaat tcctttttat ttggaaggaa
     6841 gtttttcgta accgcccaat aacgaagtct attggacggt tacgatatga tcactgactt
     6901 cgtcagtctt atctacaacc tcaaaactgt gttttgagca acctgcggct agcttcctag
     6961 ctt
//
LOCUS       DAVLMQ010000077         6873 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000077 DAVLMQ010000000
VERSION     DAVLMQ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6873
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.077"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            134..2407
                     /locus_tag="VXF95_001986"
     CDS             134..2407
                     /locus_tag="VXF95_001986"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HEV1082471.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELKVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYGKTYQAFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRSDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            2424..2894
                     /locus_tag="VXF95_001987"
     CDS             2424..2894
                     /locus_tag="VXF95_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HEV1082472.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAENDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(3011..3166)
                     /locus_tag="VXF95_001988"
     CDS             complement(3011..3166)
                     /locus_tag="VXF95_001988"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082473.1"
                     /translation="MKIKEQTRKLAAGCSKHCFEVVDETDEVSNHTYGKATLTRIEEI
                     FEEYKSS"
     gene            complement(3437..6787)
                     /locus_tag="VXF95_001989"
     CDS             complement(3437..6787)
                     /locus_tag="VXF95_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HEV1082474.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFIFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
BASE COUNT         2119 a         1487 c         1161 g         2106 t
ORIGIN      
        1 gttactctgt tctctatatt gaatttagta ctttattcat ttttattgga ttatttcctt
       61 ttgaagttaa caattccctt tctgcttttt ttttgatata ataaccttaa ctgtcattct
      121 atatggaggt tctatgcgtt ttaatcaata tagttatatc aattttccaa aagaaaatgt
      181 cttatctgaa ctaaaaaaat gtggctttga tttacaaaat acagccaatc acaaagactc
      241 acttgaaacc tttttacgtc gtttcttttt cacttatcaa gacaccaact acccactttc
      301 tatcctagca gctgataaaa aaacagacct gctgacattt tttcaatcag aagatgaact
      361 gacagcagat attttttata ctgttgcttt tcaactttta ggcttttctt atttggttga
      421 cttcgaagat agtgacgttt ttcgtaaaga aactggattt cccattatat atggtgactt
      481 gattgaaaat ctctatcagt tactcaatac tcgcaccaaa aaaggaaata ctcttatcga
      541 ccaacttgtt agtgatggtc ttattccgga ggataatgac taccactact ttaacggcaa
      601 gagtttggct actttttcta accaggatgt cattcgtgaa gtcgtttacg ttgagtctcg
      661 tgtcgatact gaccaaaaag ggctatcaga cctagtaaag gttagcatta ttcgccctcg
      721 ttttgatgga aaaatccctg ccatcatgac agccagccct tatcatcagg gaaccaatga
      781 caaggctagt gacaaggctc tctacaagat ggagggcgag cttaaggtta agcttcctca
      841 caagattgag ctagagaaac ctcaactaaa tctcgtccaa ccccaaggtc aagctgagct
      901 tatagcagag gctgaggaaa agctaactca catcaactct agctatacac taaacgacta
      961 cttccttccg agaggctttg ccaatctcta tgtctcaggt gttggtacca aagactcgac
     1021 aggtttcatg actaatggag actaccagca aatcgaggct tataaaaatg tcatcgattg
     1081 gcttaacggc cgttgccgtg cctttactga tcacacgcgc cagcgtcaag tcaaggctga
     1141 ttggtcaaac ggaaaagttg ctacaacggg actttcctat ctaggtacca tgtccaatgg
     1201 tcttgcgact acaggagtcg atggtttaga agttatcatt gccgaggcag gaatttcatc
     1261 atggtacaac tactaccgtg aaaacggtct ggtgactagc ccaggtggtt atccaggtga
     1321 ggactttgac tcccttgctg agttaaccta ttctcgtaat ctcttagctg gcgactatat
     1381 ccgtggcaat gaagctcacc aagctgactt agaaaaagtg aaagctcagc tagaccgaaa
     1441 aactggggac tacaatcagt tttggcatga ccgcaattat ctgctcaatg cccataaagt
     1501 aaaggcagag gttgtcttta ctcatggttc tcaggattgg aatgtcaaac cacttcatgt
     1561 ttaccagatg ttccatgctc ttcctactca tatacacaag catctctttt tccataatgg
     1621 tgcccatgtt tacatgaaca attggcaatc aattgacttc cgtgagtcca taaatgcctt
     1681 attaaccaag aaattactag gacaggaaac agactttcaa cttcctactg ttatctggca
     1741 ggacaataca gctccacaga cttggttatc acttgataac ttcggtgggc aagaaaactg
     1801 taaaaccttc tcacttggtc aagaagagca agctattcaa aaccagtacc cagataagga
     1861 ttttgagcgc tatggtaaga cataccaagc cttcaataca gagctctatc aagggaaagc
     1921 caatcagatt actattaacc ttcctgtgac taaagatctc cacctaaacg gtcgcgctca
     1981 gctcaatctt cgtatcaaat ccagtacaaa caaggggctc ttatctgccc aactgctaga
     2041 atttgggcaa aagaaatacc tacaacctta tccagctatt ttaagtgcta gaaccattga
     2101 caacggtcgc tatcacatgt tggaaaatct ctgtgaattg ccatttagac cagaggcaca
     2161 acgagtcgtg acaaaaggtt accttaattt acaaaataga agtgatttac tgttagtaga
     2221 ggatattact gcagatgaat ggatggacgt tcaatttgaa ctgcagccaa ctatttacaa
     2281 gctaaaagaa ggagacactc tccgtttagt cctctatact actgactttg aaatcaccat
     2341 ccgtgacaat acagactacc acttgactgt cgacctcgct cagtccatgc ttaccttacc
     2401 ttgctaaaag gagttacatt attatgaata aatcagaaca ccgccaccaa cttatacgcg
     2461 ctcttatcac aaaaaacaag attcatacac aagctgagtt gcaagccctt cttgctgaga
     2521 acgacattca agtaacccag gcaaccctct cacgcgacat caaaaatatg aacctatcaa
     2581 aagtccgcga agaagatagc gcttattatg ttcttaacaa tggttccatc tcaaaatggg
     2641 aaaaacgtct cgaactctac atggaagacg cccttgtctg gatgcgccca gttcaacacc
     2701 aagtcctact aaaaaccctt cctggactgg ctcaatcctt tggttctatc attgatactt
     2761 tgagcttccc tgacgctatc gctacccttt gtggtaatga tgtctgtctt atcatctgtg
     2821 aagatgcaga tactgctcaa aagtgctttg aagaactgaa aaaattcgcc ccaccatttt
     2881 tctttgaaga ataataaatg actacaacta acaattatgc ttaaaaaaaa actggtagaa
     2941 agtctttaac atcagaaaac gcatagtatc aagtgttgaa aacccttgat actatgcgtt
     3001 ttgctttatc ctaggaagat ttatactctt cgaaaatctc ttcaatccgc gtcaacgtcg
     3061 ccttgccgta ggtatggtta ctgacttcgt cagtttcatc tacaacctca aaacagtgtt
     3121 ttgagcagcc tgcagctagt ttcctagttt gctctttgat tttcattgag tattatttca
     3181 ttttctcctg caattgaatt cttgctcagc tttttgtttt ctatttcttt aaaatcaaag
     3241 tagctctttt gttaataact cgatcaacaa acatcgtggt acaagtatct actttgaaat
     3301 ttatcaacca cttaacaact gatactgtat tctaggaaaa cgatgacatt cttcctaata
     3361 aaacttctca tatatagcat aaatttctac tctttttaat tttaaatgag tctcagcatg
     3421 gcaatcactt tagaatttaa gccgcttctc cagctcgatt attgataagt tcaatgattt
     3481 gaacaatatt acgaagtact ggtagttggt gttggaagag tagttgaaca gatccataag
     3541 atttaaacgg ctcttgcgtt aacactttcg tctctaaaaa accattttct acaatgtagt
     3601 ctacaatcaa ttttacaaat gaaatctgcc tggcattaag attctcatcc gacaaaaatt
     3661 tagaaaaaat acgattggca gactctctat ctaaaccaat aatctcacga accaatctcg
     3721 gaattgcctt attttcataa tgactttggt agtctgcttt actacctaat ttttcccaaa
     3781 gcaatttttc aagtgcaagc atatcatcag atgtcaactt tttattatgg tatagcttag
     3841 aaatggactc ctcatccaga tgagttttca aataatgctc aactttttca ttgtaagacc
     3901 gaagatcgtt gacctgcaaa aatgctgtgg tctcgtgaac agtggagagt atacgatctt
     3961 caaagttaac atagtagggt ttacggtctg ttttatccaa aaactgtaat aaatctcgaa
     4021 tagcaagacg aattttttcc aaatcagaca agttaacttc tttccaaaat tcaggctcct
     4081 gtactttcct gataatttca gcctgctcaa aaacctgcgg gatattgcca atagcagaaa
     4141 gagctctagc cgtcttcatc acttgggaaa tatgaacagt ggaagattta gctgtcagtt
     4201 gccccaactg aatatgaagc aaccacaaat caaatctcct cgccatctca tcttctttat
     4261 cttcatcaaa taaaagcgga gagagatttt tttgaatggt ttcacttgta acagcagtta
     4321 gattctgcca actttccaat ttcctatagc tataaactgt atctaaaacc atacgaaccc
     4381 tgaagtccaa ctcatttaag ctctctatac gaccttgaag ttccgagaca agctgctgac
     4441 ggtatgctct cgcaaactga tcttcttggt attggagtcc ctgaagttct cgaatcaagt
     4501 ccactttgat attaaataaa cgctgagtca gcgaaacaat gtgacgaccc tctccatctc
     4561 ttggatctgc acgaaaataa tcaaaattgt ccccataatc aaataccaag aagttttcct
     4621 tatcctgctc aggtccaaat aaatctttac atagacgggt tcctcgacca atcatctgcc
     4681 aaaacttagt tttagagcgt actttcttga agaagactaa attaacaacc tctggtacat
     4741 caatacctgt atctaacata tcgacagaaa tcgcaatttg aggatacttc tccttaattt
     4801 taaaatcatc aatcaaggtc tgataatgct taatactata atcaatcacc tgagcatagt
     4861 cgctcccttt ttcaggatag cggttgttaa aaatacctct gatatattcc gcatggtcat
     4921 gatttttagc aaaaataata gttttaccaa tttcatcacc cgaggctgtc tgaattcctc
     4981 ttgtcatgag ttcatttaaa acaatttcta ctgtactttt attgaaaata aaggaattaa
     5041 acacactccc atcaatatct ttttcacagc tatcgtcttc aaatttgcta tcaaaatgtt
     5101 ccttttcttc ttcggacaaa tcatcataat gtagaccatc cgtaggtagt ttcagtttgg
     5161 tttcgataga atgataggct actaaatatc cgtctttaac agcctcttcc aaatcatatg
     5221 catatgttgg aaccccattc tccaaattaa agaatccata ggtgttttta tctaaatctt
     5281 gacgcggagt agctgttaag cctacaattc ttgcatcaaa ataatcaaaa atggacttgt
     5341 atttctgata aatagaacgg tgagattcgt caattatgat aaggtcaaaa tgcccaacag
     5401 tgaaagggcg ttgatttact tcttcttgac cactaatcgc tccaatcatg gtcggataag
     5461 ttgaaaagac catgcgactt gattgagctc cttctttatc ttctaagaag ttacaaacgg
     5521 aaagatctgg gagtaatttt ctaaacgaat cataggcttg cttaaccaag gaagttctat
     5581 cggctaagaa gagaacgttt tttacccagt tatgacgtga taagatatca actagagaaa
     5641 ctgctgtacg agttttccca gccccagttg ccataaccaa aagtgcctgt ctacgatgat
     5701 tagagaaagc ttcacaaacg cttgcaatgg cgtgtttttg gtagtgacgc ccggaaatat
     5761 cgtccctaat tttactagaa atatcctcaa gtggtttttg aagatgacgt ctatccatca
     5821 ctaattgcaa ttcttcttga gagtaaaagc ctgcaatctg gcggcggttc ggaccatcaa
     5881 gtatatagtg cttcaagcca tttgtaataa agcaaattgg ctgatagccg atatgtttct
     5941 caagagcttc agcatattct ttgacctgta cttcccctac ttctggattg acagaggctt
     6001 ttttagcctc tacaatcgct aaaattttcc catttttacc ataaagtaca tagtcacagt
     6061 aaccaattcc tgaaccgtgc ttgagaccat caacggctat ctcaacacga cagttttctt
     6121 caaatatcca tcctgctaaa cggagatcga tatcaataaa gagctttctt gtctctgcct
     6181 cagataattg atcaatatgg aaaggcacat cttgccgttg cgctgcagtc tcacgttttt
     6241 cagtataagt ctcttgaact tctacggact gagcagccat ctgttcatga aaatcaggca
     6301 gttctggtaa actgtcttgt aactttatca tagattgtgg agtttctcgg tatttgatgt
     6361 ttgctgaaag tggtaagcac ttctcatcaa aataacgctc cacaaactca ttgctgtaac
     6421 aataatcgat aaaattaaca aactgataca aatgatgcaa agctaaaatc gcttctcgtt
     6481 ccttaatttc accaccatga gcagcatggt ttccccaccg aatcaacaga actatctgct
     6541 tgtggagttc agaatctacg atatccctaa aatcatcatc ccatactaaa gaagatagag
     6601 tagcacgata gggagcttct aaatatgaat cgtgactata tatccaatgg acagcctgct
     6661 ctaaagcacg acgcgccata aaggcagtag ccacagttga tgtagcaatc atattctcag
     6721 cttcaatgca aggttttgaa aaagattcat attcgtcatt ttttaaaaga aagctaaaat
     6781 ttcccatttt tttctcactt taaacaaata gtttagctat attatactaa atttcaagct
     6841 atttctccac acttttatag ctatctcaca agc
//
LOCUS       DAVLMQ010000078         6871 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000078 DAVLMQ010000000
VERSION     DAVLMQ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6871
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.078"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            322..882
                     /locus_tag="VXF95_001990"
     CDS             322..882
                     /locus_tag="VXF95_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1082475.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     gene            883..2268
                     /locus_tag="VXF95_001991"
     CDS             883..2268
                     /locus_tag="VXF95_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082476.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSNGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDYMVELRDGKLREVFQIPS
                     YEMTQVASKEVAASPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            2270..2920
                     /locus_tag="VXF95_001992"
     CDS             2270..2920
                     /locus_tag="VXF95_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HEV1082477.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQELHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            2931..3623
                     /gene="tenA"
                     /locus_tag="VXF95_001993"
     CDS             2931..3623
                     /gene="tenA"
                     /locus_tag="VXF95_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HEV1082478.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            3628..4152
                     /gene="thiW"
                     /locus_tag="VXF95_001994"
     CDS             3628..4152
                     /gene="thiW"
                     /locus_tag="VXF95_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HEV1082479.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFSERID"
     gene            4152..4955
                     /locus_tag="VXF95_001995"
     CDS             4152..4955
                     /locus_tag="VXF95_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1082480.1"
                     /translation="MQEFTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     SREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSKNQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            4948..5580
                     /locus_tag="VXF95_001996"
     CDS             4948..5580
                     /locus_tag="VXF95_001996"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1082481.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARQVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPI
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(5789..6580)
                     /gene="thiD"
                     /locus_tag="VXF95_001997"
     CDS             complement(5789..6580)
                     /gene="thiD"
                     /locus_tag="VXF95_001997"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HEV1082482.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPESVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     regulatory      complement(6664..6762)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
BASE COUNT         1902 a         1349 c         1482 g         2138 t
ORIGIN      
        1 atgataccca ttgaacctga tacagttaag actggcgaag ggaaatgtga aatgtttttt
       61 tcgtatgtcg aaaagaactg tctaatcttg taagctgaac tctaattcgt atctgtaatt
      121 agagtttttt cttttacgaa actggatgaa gatgatatag tagattgaaa taagatgcga
      181 acaaatcaat tataaaattc aaattaattt ctagaaatat tttagtgttc ttgtgtactg
      241 ttctaaattc agtctgctat acaaagtatt taggtctgtc ttcttgagtg ccccactttt
      301 ctttaaaaaa aggagttttt tatgttgaaa aaatggcagt taaaagatgt tatcttgctt
      361 gctttcttgt ctatcttttt tggtggggtt ttcgttggtt caggatatgt gtataatatt
      421 ctcagtctac tcttaacacc tcttggtttg caggcctttg ccaatgaaat cctcttcggt
      481 ctctggtgta tggctgcgcc cattgctgcc atctttgttc cgagagtcgg aagtgcaacg
      541 attggagaag tgctagctgc gcttgctgaa gtcctttatg gtagccaatt tggtctagga
      601 gctcttttgt ctggcttggt tcaaggtttg ggaagtgaat ttggttttat cgtaactaag
      661 aatcgctatg aaagttggct ctctctaact gctaatagta ttgggattac gcttgttagc
      721 tttgtctatg aatacattaa gttaggctac tacgcctttt cccttccgtt tgtcctttcc
      781 ttgcttgtgg tacgttttat ttctgtttat ttcttctgta ccatcttggt tcgtgccatt
      841 gtcaaactct atcatcagtt tgcaactgga ggaaaagcat agatgggtct ggaactacga
      901 gcgattcagt ccccaatctt ctctgagccg tttgatttta cttttcatgc gcaagccttt
      961 accttgttag ttgggagcaa tggttcagga aaatccagcc tctttcaaat gattgcccaa
     1021 gtcagttctc ttccctatag tggtcaagtc ctgatagatg ggagcgaggt cagtcagctt
     1081 tctatcatcg cacgtgtcca gaaggttggc attctcttgc aaaatcccaa tcatcaattt
     1141 accatggaga acttgtttga ggagctgatt ttcaccttgg agaatatcgg ctatcacctt
     1201 caggaaattg attctaaaat agcagaggtt gtccagcaat gtcgttgcga ggcaatctta
     1261 caccgtccca ttcatcacct atcaggtggg gaaaagcaaa aagcagcgct ggctgtcctc
     1321 tttgccatga atcctagggt ctatctcttg gatgagccct tcgcttccat tgaccgcaag
     1381 agtagaatcg agatattgga gattctaaaa gagttggctc ttgatgggaa gacagtcatt
     1441 ttgtgcgacc atgatttatc tgactataaa gcctatatcg actatatggt tgagctaaga
     1501 gacggaaaac taagggaagt gtttcaaatc ccttcctatg agatgacaca ggttgcttca
     1561 aaggaagttg ctgctagccc ggaattattc catatgaacc gtgtgactgg tgagcttggt
     1621 aatcgccccc tcttttcaat tgctgatttc acattctatc aagggatttc ctgtatcctg
     1681 ggtgacaatg gtgtcgggaa atcaaccctc tttcggtcta ttcttcaatt tcaaaagtat
     1741 aaggggcgca ttgcatggaa ggggacagtc ctgaaaaaga aaaagagttt gtaccgtgat
     1801 ctgacgggtg ttgttcagga agctgagaag cagtttatcc gagtcagtct gcgagaggag
     1861 cttcaattag atggacctga ttctgaaaga aatcagcgga tttttcaagc tttacgatat
     1921 tttgatttgg agcaggcagt cgataagagt ccctatcaat taagtggtgg tcagcaaaaa
     1981 attcttcagc tcctgaccat cttgaccagt aaggcttccg tgatcttgct agatgaacct
     2041 tttgcaggtt tggatgatag agcctgccat tatttttgca agtggattgt ggaggagagg
     2101 aaccaaggaa gaagttttct gctcattagt catcgtttag accctttgat ttctgtggtt
     2161 gattattgga ttgagatgac tagtcagggt cttcggcatg tgaaagaagt gaccattacc
     2221 aaaccactta catctcagag tagcaatacc caaggggagg tgagatagta tggtcaaagt
     2281 agcaacccag acaccgatta tcagtctctt cttgctgatt ttatccttgg aaacatcttt
     2341 cattccttcg attgctctga atctttcggt agtcgcattt tgtattctct ttatgctcta
     2401 ttaccgtcga tttaaaatgt tagcttggat gatcatactt gccattttac catcttttgc
     2461 caactactgg gcagttcagt tacacggaga tgcttcacag gcagtcatgc ttggaacgag
     2521 ggcttttgtg acagtttgta tcggccttgt ctttgtttcc tctatttcac taaaagagct
     2581 tctcttgtac ttggctcaaa aggggctatc acgctcttgg tcctatgcct tgattgtggt
     2641 attcaattcc tttcctctca ttcagcaaga aatcaagtcc ctcaaagaag cttgcctatt
     2701 acgtggtcaa gaactacatt tttggtcgcc cttgatttac agtaaggttc tgatgacagt
     2761 ctttaggtgg cgccatcttt acctgagagc tctatctgct cacggatatg acgaacatgc
     2821 acagttgaag aatagctatc ggacttttta tattcctaaa aaaacaaaat taatctacct
     2881 gcttttcttt ttattgcttc aaaccagtct atttttataa aggagttatt atggaattta
     2941 cagatattgc gatggaatta tccaagaaag cttggcaggc ttcctttcat catcccttta
     3001 ttttacaatt acaagagggg aatttagaac ctgccatttt ccgctattac ctgattcagg
     3061 atgcctacta tctgaaggct ttctcagaaa tctatcatct gttggctgat aagacttcaa
     3121 accaagagat gaaaagactc ttgaaacaaa atgctcaggg tttagtggag ggtgagttat
     3181 ttattcgcca acaatttttc aaggaattgg aaatcaacga ccaggaaatg gagcaacatc
     3241 caatcgctcc aacctgttat cattacattt ctcatattta taggcaattt gcagaaccga
     3301 acttagccat agcttttgca agcttgcttc cttgtccttg gttataccat gatataggca
     3361 aatcacttaa tcttaaacca tcaccaaatc ctctctatca acaatggatt gaaacttata
     3421 ttacggatga gttagagcaa cagatcagag aggagggagc actggtcaat cagctctatc
     3481 gagaaagtga tgagacagat aagcaaaaaa tgctagatgc cttccacatc agtgttcata
     3541 tggaagccaa gttttgggag atggcttacc aacaccagac atggaagagc gatttacagt
     3601 ctttagaaaa aggagaagaa tagaaacatg agaaagcacc aactacaagt tcacaaattg
     3661 accattttat ctatgatgat tgcccttgat gtagtcctta cacctatctt tcggattgag
     3721 ggaatggcac cgatgtccag tgtagtcaat attctagcgg gaatcatgat gggacctgtt
     3781 tatgccttgg ctatggctac agtgacagcc tttatccgta tgacgactca agggattccg
     3841 cctttagctc tcacaggagc gacttttgga gcccttctag caggtctctt ttataagtac
     3901 ggtcgaaaat tttacttttc tgccttggga gaaattgtgg gaacaggtat tattggttct
     3961 attgtttcct atcctgttat ggtactcttt acaggatcag ctgctaagct tagctggttt
     4021 atctacacgc ctcgattttt cggagcaacc ttgattggta cagcgatttc ctttattgcc
     4081 tttcgatttt taatcaagca ggaattcttt aaaaaagtgc agggatattt ctttagtgaa
     4141 aggatagact gatgcaggaa tttacaaatc cctttcctat aggctctagt tccctcattc
     4201 actgtatgac caatgagatt tcttgtgaga tgctggcaaa tgggattttg gctctgggat
     4261 gcaaacctgt catggcagat gattcccgtg aagttcttga ttttactaag caaagtcagg
     4321 ctctcttcat caatttaggt catttgtcag ctgagaagga gaaagcaatc cgcatggcag
     4381 cttcgtatgc aaaccaatct tctctcccga tggtagtaga tgcggttggc gtaacgactt
     4441 catccattcg taagagctta gttaaagacc ttttagacta tagacctacg gtccttaaag
     4501 gaaacatgtc agaaattcga agtcttgttg gattaaagca ccacggcgtt ggggtcgatg
     4561 cgagtgctaa agatcaagaa acggaggatt tgcttcaagt cttgaaagac tggtgtcaga
     4621 cctatcctgg tatgtcattc ttagttactg gccccaagga cctcatcgtt tcgaaaaatc
     4681 aggtcgctgt actggagaat ggctgtactg aattagactg gataacaggg acaggagatt
     4741 tggttggagc cttaacagcc gtttttctca gccaaggaaa gactggtttt gaagcttctt
     4801 gcttagcagt ctcttatctc aatatcgctg ctgagaaaat agttgttcaa ggaatgggat
     4861 tggaagaatt tcgttaccaa gtactcaatc agctttcgct cctaagaaga gatgaaaatt
     4921 ggctagatac catcaaagga gaggtttatg aatagagaag cacttagact atatctggta
     4981 accaatcgct atcaagattc cgtggaaagc tttcttgcaa aagttgagac ggcctgccgt
     5041 tcaggggtta ccatagtcca attgcgagaa aaaaatctca caaccaatca atattatcaa
     5101 ctggcaaaac aagtcaagga aataacagat gcttatcagg tacccttgat aatcgatgat
     5161 cggttggatg tttgtcttgc ggttgatgct gctggtctgc atattggaga tgacgaactc
     5221 ccagtttcgg ttgcccgaca agtcttgggt cctgaaaaaa tcctcggtgt caccgctaaa
     5281 acggttaaaa gagctctgga agcggagaaa tcaggtgcag attacttggg gacaggagcc
     5341 atttttccga caaccaccaa ggaaaatgca cccatcaccc tgatttcaac cttgaaaaca
     5401 atttgccaaa cggttgccat tccaatagtt gctattggcg gcttgacttc ggagaatatt
     5461 gatcagctta tgggcactgg catagctggt gtagctgttg tacgtgattt gatgcaagca
     5521 gaagatattg aggcaaaaac gcaagccttt ttaacaaagt tgcatgacat tctttcctaa
     5581 ttaatactca atgaaaatca aagagtaaac tagaaagcta gtcgcaggtt gctcaaagta
     5641 ctgccttgag gttttagata agactgacga agtcagctca aaacagtgtt ttgaagttgc
     5701 agatggaagc tgacgtagtt tgaagagatt ttcgaagagt ataaaaactc tctaattccc
     5761 ttaaagtggg aactagagag tttttttctt aatctttaaa agttgtatgg ttgactggac
     5821 cagaaccatg accgagttga ggggcatctt gaatagcttt tgtgataaag gccttggcct
     5881 tatcaactgc ctggtaaaga ctcttgccct tggctagttc agcagtaatc actgcagcaa
     5941 aggtacatcc agtaccatgg gtgtgacagg tttgaattcg tgggctttcc cagacaaatt
     6001 gttcattctt ggtaaagagg aaatctttag caccaccttt gagatgtccg cctttgataa
     6061 ccacagactc aggaccaaat tcttttaaaa tcaggcgacc agcacgctgc atgccttcgg
     6121 ggtcatggat tgaaaaacca acaatctctt ctgcttcagg aagatttggc gtaataatag
     6181 ttgctagagg tagtaagttt gttttgagat agtctctagc acttgagtca atcaaggcat
     6241 ctccacttgt agcaaccata acaggatcaa ggacataggg acaatccagt tttttaagat
     6301 agggttggat gatttccatg atttcagtag tagccaacat tccagttttt acagcctgag
     6361 gtggaatatc agaaaagaca ctctccaatt gggctttcaa catttgagga gaaacatgct
     6421 cgattagctg aacacctctg gtattttgag cgacaagact ggttacaaca gccattccat
     6481 agacatctct cgcttggaat gactttaaat ctgccataat gccagcacca ccactagggt
     6541 cagtccctgc aatggtcaaa gcaacgggta aataagtcat ctaaaacctc ccaaccaact
     6601 gaagtttgta ttcttaagaa caagctagtc tgttttagaa aggcaataga agactgctag
     6661 tccccattat catttccact tccatcagct agtattacct agattgagtc agagggatct
     6721 aacagtcgtt aatctcagct ttacgcaccc ctagtggttg ttttcttttt tctttagtat
     6781 agcatatttt tattgtttat atagtaatat ttgactgcaa atcgtttttc aaatgattaa
     6841 aattctattt ttcgaagaaa atattatttc t
//
LOCUS       DAVLMQ010000079         6476 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000079 DAVLMQ010000000
VERSION     DAVLMQ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.080"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            357..1403
                     /gene="pheS"
                     /locus_tag="VXF95_001998"
     CDS             357..1403
                     /gene="pheS"
                     /locus_tag="VXF95_001998"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HEV1082483.1"
                     /translation="MSTIEEQLKALREETLASLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            1403..1912
                     /locus_tag="VXF95_001999"
     CDS             1403..1912
                     /locus_tag="VXF95_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082484.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GIGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            1989..4394
                     /locus_tag="VXF95_002000"
     CDS             1989..4394
                     /locus_tag="VXF95_002000"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HEV1082485.1"
                     /translation="MLVSYKWLKELVDIDVPSQELAEKMSTTGIEVESVESPAADLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEEARQIVCGAPNVRAGIKVMVALPGARIADNY
                     KIKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPENTVPGEEVFSYLDLDD
                     EIIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIGTDK
                     APYYAARILDNVIIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDT
                     FEGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKS
                     SRVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASMIAELAGA
                     TVRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFT
                     VSVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTVTQKLRRQVRTIAE
                     GAGLTEIITYALTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNV
                     ARKNKNLALYEIGKVFEQTGNPREELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYA
                     KGILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIP
                     ETYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVK
                     RLTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQVSLEEKVNA
                     EVR"
     gene            complement(4462..5463)
                     /locus_tag="VXF95_002001"
     CDS             complement(4462..5463)
                     /locus_tag="VXF95_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1082486.1"
                     /translation="MIKTFLSALSVILFVIPIIAYSFFPSSNLNIWLSTRPILAQIYA
                     FPLATATMASILSFVFFSLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NALPPFERGTWNSQSPKLFNATIDHILLPKNHYYVRDLDIVSFQNSDHRCIFTEITF"
     gene            5610..6013
                     /locus_tag="VXF95_002002"
                     /pseudo
     CDS             5610..6013
                     /locus_tag="VXF95_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            6139..6405
                     /locus_tag="VXF95_002003"
     CDS             6139..6405
                     /locus_tag="VXF95_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082487.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARYEQGISQKKLEEV
                     SGISQPVIARMETGESSLQLDTVLKVLTSLGKTLAVVPLEQGKS"
BASE COUNT         1979 a         1204 c         1483 g         1810 t
ORIGIN      
        1 attttacttt cccaatcgat ttgttttcat cttatttcaa tccgctataa agttagataa
       61 gaataagcta acaagcagaa gtaagatagg tcttgcaaga atggtaaaaa tctgataaac
      121 taagtagtaa ttgaatagga atctgaaaga ctagtagccc aagggaagta tatcagggag
      181 gagagccgtg actgcaagct ctctatatga aagctgggtg aattcacttg cgcatggatt
      241 tagaaatgaa ggtctgactt gtcagatgaa aacggatggt accgcgtgtc aacgctccga
      301 gtggagtttt tggcatgtgg ttttcttttt atctacgaga gactgatgga ggaaatatgt
      361 caactattga agaacaatta aaagcgcttc gcgaagaaac gctggctagc ttgaagcaga
      421 ttactgctgg aaatgaaaaa gagatgcaag atttgcgtgt ctctgtcctt ggtaaaaagg
      481 gttcgctcac tgaaatcctc aaagggatga aagatgtttc tgctgagatg cgtccaatca
      541 tcgggaaaca cgtcaatgaa gctcgtgatg tcttgactgc tgcttttgaa gaaacagcta
      601 agctcttgga agaaaagaaa gtcgcggctc aactggctag cgagagtatc gatgtgacgc
      661 ttccaggtcg tccagttgcg actggtcacc gtcacgtttt gacacaaacc agtgaagaaa
      721 tcgaagatat cttcatcggt atgggttatc aagtcgtgga tggttttgaa gtagagcaag
      781 actactataa ctttgaacgt atgaaccttc caaaagacca cccagctcgt gatatgcagg
      841 atactttcta tatcactgaa gaaatcttgc tccgtaccca cacgtctcca gttcaggcgc
      901 gtgctatgga tgcccatgat ttttctaaag gtcctttgaa gatgatctcg ccagggcgtg
      961 tcttccgtcg cgatacggac gatgcgaccc acagtcacca attccaccaa atcgaaggct
     1021 tggtagttgg gaaaaatatc tctatggctg atcttcaagg aacgcttcag ttgattgtcc
     1081 aaaaaatgtt tggtgaagag cgtcaaattc gtttgcgtcc atcttacttc ccattcacag
     1141 agccatctgt tgaggtggat gtttcttgct tcaagtgtgg tggagaaggc tgtaacgtat
     1201 gtaagaaaac aggttggatc gaaattatgg gagccggtat ggttcaccca cgtgtccttg
     1261 aaatgagtgg tatcgatgcg actgtatact ctggttttgc ctttggtctt ggacaagagc
     1321 gtgtagctat gctccgttat ggaatcaacg atatccgtgg attctaccaa ggagatgtcc
     1381 gcttctcaga acagtttaaa taatgattag aaaagtagaa atggcagatg ttgaggtgtt
     1441 ggctaaaatt gccaaacaag cctttcgtga aacctttgcg tatgataata cggaagagca
     1501 gttacaggaa tactttgaag aggcttatag tctgaaaact ttgtcaactg agttgggaaa
     1561 tcctgactct gaaacctatt tcattatgca tgaggaggag atagctggtt ttctcaaagt
     1621 caactgggga agtgctcaaa ctgagagaga attagaggac gcttttgaaa ttcaacgcct
     1681 ctatgtgcta caaaaattcc aaggatttgg aataggtaag caactgtttg aattcgcact
     1741 tgaacttgct acaaaaaata gtttttcttg ggcttggcta ggtgtttggg agcataatac
     1801 aaaagctcaa gcgttttata atcgatatgg ttttgaaaaa tttagccaac atcattttat
     1861 ggttggtcaa aaagtagata cggattggtt actgagaaag aaattaaggt aagaagagga
     1921 ttcttctatt gaaatgatag gaaaggaaaa gaaccagtgt ggcaatggtc attctggaga
     1981 actaaattat gcttgtatct tataaatggt taaaagaatt ggtggacatt gatgtgccat
     2041 cacaggagtt ggctgaaaaa atgtcaacca cagggatcga ggtagagagt gtcgaatcac
     2101 cagctgctga tctctcaaaa attgttgtcg gtgaggtctt gtcttgcgaa gatgtgccag
     2161 agactcacct ccatgtttgt caggttaacg ttggcgaaga agaagcccgt cagatcgttt
     2221 gtggtgcccc aaatgtgcgt gctgggatca aggtcatggt ggctcttcca ggagctcgta
     2281 tcgctgataa ctacaaaatc aaaaaaggaa aaatccgtgg tttggagtca cttggaatga
     2341 tctgttcact tggtgaattg ggaatttctg actcagttgt gcctaaggaa ttcgcagatg
     2401 gcatccaaat cttgccagaa aataccgtgc caggtgagga agtcttttct tacctagact
     2461 tggatgatga aatcatcgaa ctttccatca caccaaaccg tgcagatgcc ctttctatgt
     2521 gtggagtggc tcacgaagtg gcagccatct atgacaaggc ggtcaacttt aaagaattta
     2581 ctctaacaga aactaatgaa gctgcggcag atgccctttc tgtcagcatt gggacagaca
     2641 aggcgcctta ctatgcagct cgtatcttgg acaatgtgat tatcgcacca agtccacaat
     2701 ggttgcaaaa ccttctcatg aacgaaggca tccgtcccat caataacgtt gtagacgtga
     2761 caaactacat cctgctctac tttggtcaac ctatgcatgc ttttgacttg gacacatttg
     2821 aagggactga catccgtgtg cgtgaagcgc gtgctggtga aaaattggtg accttggacg
     2881 gtgaagaacg tgacttggac gtgaatgacc tagtcatcac tgttgcagac aagccagtag
     2941 cccttgcagg tgtcatgggt ggtcaagcaa cagaaatctc tgaaaaatct agtcgtgttg
     3001 tccttgaagc tgctgttttc aatggtaaat ctatccgtaa gacaagtggt cgcctgaacc
     3061 ttcgttcaga atcgtcttct cgctttgaaa aaggcatcaa tgtggcaaca gtcaatgaag
     3121 cccttgatgc ggcagctagc atgattgcag aacttgcagg tgcgacggtg cgtaagggta
     3181 tcgtttcagc gggtgagctt gatacctctg atgtggaagt ttcttcaacc cttgctgatg
     3241 ttaaccgtgt cctcggaact gagctgtctt atgctgatgt cgaagacgtc ttccgtcgtc
     3301 ttggttttgg tctttctgga aatgcagaca gctttacagt cagcgtacca cgtcgtcgtt
     3361 gggatatcac aatcgaagct gacctctttg aagaaatcgc tcgtatctat ggatatgacc
     3421 gcttgccaac tagtctacca aaagacgatg gtacagctgg tgaattgact gtgacacaaa
     3481 aactccgccg tcaagttcgt accattgctg aaggagcagg tttgacagaa atcatcacct
     3541 atgctctaac aactcctgaa aaagcagttg agtttacggc tcaaccaagt aaccttacgg
     3601 aactcatgtg gccaatgact gtggatcgtt cagtcctccg tcaaaatatg atttcaggta
     3661 tccttgatac cgttgcctac aacgtggctc gtaagaataa aaacttggcc ctttacgaga
     3721 ttggaaaagt ctttgaacaa acaggtaatc caagagaaga acttccaaat gaaattaaca
     3781 gttttgcctt tgccttgaca ggcttggttg ctgaaaaaga tttccaaaca gcagcagttc
     3841 cagttgattt cttctatgct aagggaatcc ttgaagccct atttactcgc ttgggactcc
     3901 aagtaaccta tacagcaaca tctgaaatcg ctagccttca tccaggtcgt acagcagtca
     3961 tttcactcgg tgaccaagtt cttggtttcc ttggccaagt gcatccagtc actgctaagg
     4021 cttatgatat tccagaaacg tatgtagctg agcttaacct ttcagctatc gaagctgcgc
     4081 ttcagccagc gactccattt gtagaaatca ccaaattccc ggcagtcagc cgtgacgttg
     4141 cccttctcct caaggcagaa gtgactcatc aagaagttgt agatgctatc caagctgccg
     4201 gcgtgaaacg tttgacagat atcaaactct ttgacgtctt ctcaggtgag aaattgggac
     4261 ttggtatgaa gtcaatggct tatagcttga ccttccaaaa tccagaagat agcttaacgg
     4321 acgaagaagt cgcacgctat atggaaaaaa tccaagtatc gctcgaagaa aaagtgaatg
     4381 cagaagtgcg ttaaacgata gtatgataca aattccccct ctagtttatg aacactagag
     4441 gggtgatttt atataaaata attaaaatgt gatttctgta aaaatacatc tatgatcaga
     4501 gttttgaaaa cttacaatgt ctaaatctct aacatagtag tggtttttag gcaataagat
     4561 atgatctatc gttgcattaa aaagttttgg actttggcta ttccaagttc ctctttcaaa
     4621 aggtggaagt gcattcaatg cgtccctatg agagcttatt tttgcaagtg ctccatgacg
     4681 catagttgca ttaaaatcac ctgcaataat agcctttgga tattttgaag ccaattgatt
     4741 atgaatgatg tttaagtctt gcttccagat ttccattaaa cctggcagag gaggagcagt
     4801 atgcaaggca atgatatctg gtatattttg ttttctcgaa tgtaatacaa ttgtcccgaa
     4861 ccgtgttgta tgaaaagttt tagcttctgt atagaaacca taacttttct tgacaatcac
     4921 agtcacagga gctattccac tattggtagg tggagaagtg aaaatatcat agttggccat
     4981 agaaagtcca acttgatgaa acaatagttt gattctctgg ttttcttgct cacctctgat
     5041 attggtagct agttcaggga atatagccat atcggcatca aaatggctaa aaattcgctc
     5101 aatatgttgt gcttctattt gattagcgac gttccaagtt actaatttta aggttttagt
     5161 cttatttgat gcagaagaaa gggttttatc tgttccgaat aatagtaata tgagcgatag
     5221 taagagcaaa atgccagagt aaaaccgtat ttgtttattt ttcttgtaaa aagataggga
     5281 aaaaaatacg aaacttaaaa tagaagccat agttgcagta gctaagggga aggcataaat
     5341 ctgtgccaag ataggtctgg tagatagcca aatattaaga ttagaagatg gaaaaaaaga
     5401 ataagctatg atagggataa caaagagaat gaccgaaagg gcagagagaa atgttttaat
     5461 cattgtgtga gtacctcaat ttgcaatggt tgctcggagc taatgtgact ttacttgatt
     5521 gatattcttt ttcttgtctt cctcatagat taagtacaac ccaagtaaaa aagttcaatt
     5581 taagattgaa atgattaaaa ggcacagaaa tgcaagacaa ttatactaca aaaggcaaac
     5641 atttgacaat cgatagccgt cgcttaatcg aacgatggaa aaaagaagga aaatcaaata
     5701 gagaaattgc ctctctactt ggaaaagctc ctcaaactat ccacactgaa atcaagcgtg
     5761 ggacagtccg acaatgtctt ggaaaagggc gcttcaaaga gatttattct gccgactacg
     5821 ctcaacagtc ttaagaaact aaaggaaaag attctccact atacataacc aaaaattttc
     5881 gcctgaaatg atggtgatgg ctaaaggggt taacgtggga atttcaacca tttactattg
     5941 gattcatcgt ggaaaattgg ggttaagcaa gcaggatctg ctttatccta gaaaaggaaa
     6001 atcgcttaag aaataggcta gcaccaactt taaacccgct ggtcaatcta tcgaatcata
     6061 attcgctcat ttttttaaaa atacatagac gtaaaaaaaa gagggttaag tgatgaagaa
     6121 tagtgctatt gggagtaatt ggaaggatgt ccatctgagc tctttagcaa ggaggaaatc
     6181 cttgaaagtg atatgcgagt ggctatcatg agcgagttga ttgaggctag gtatgaacaa
     6241 ggaatcagtc agaaaaagct ggaagaagtc agtggaataa gccagcctgt catagctagg
     6301 atggagacag gagagagcag tcttcagttg gatacggtct taaaagttct aaccagtcta
     6361 ggaaagacac tagcagtcgt tccacttgaa caggggaaaa gttgactaga atcagttata
     6421 gtcttttcta ataacaggtc atagtcactt ataagaatta ctaataacat gtttta
//
LOCUS       DAVLMQ010000080         6419 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000080 DAVLMQ010000000
VERSION     DAVLMQ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6419
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.081"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            53..448
                     /locus_tag="VXF95_002004"
     CDS             53..448
                     /locus_tag="VXF95_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HEV1082488.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKFFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     gene            459..830
                     /locus_tag="VXF95_002005"
     CDS             459..830
                     /locus_tag="VXF95_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HEV1082489.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QAGEFGFACGMNMMHGKMIVE"
     gene            840..3083
                     /locus_tag="VXF95_002006"
     CDS             840..3083
                     /locus_tag="VXF95_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HEV1082490.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLAISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QAAGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            3290..5065
                     /gene="spxB"
                     /locus_tag="VXF95_002007"
     CDS             3290..5065
                     /gene="spxB"
                     /locus_tag="VXF95_002007"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HEV1082491.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            5176..5523
                     /locus_tag="VXF95_002008"
     CDS             5176..5523
                     /locus_tag="VXF95_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HEV1082492.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEIEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(5640..6419)
                     /locus_tag="VXF95_002009"
                     /pseudo
     CDS             complement(5640..6419)
                     /locus_tag="VXF95_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         1900 a         1221 c         1440 g         1858 t
ORIGIN      
        1 aagagtatac tgatgagtgt aattgacaaa tgtagatttt ggaggtatgg taatgcagat
       61 ttcagatgca gaatggcagg tcatgaagat tatttggatg cagggggagc agaccagtac
      121 agatttgatt agggttttgg cagagcggtt cgactggtcc aagtcaacca ttcaaactct
      181 tttggctcgt ttggttgaga aagagtgtct gactcggaaa aaagaaggca agttctttgt
      241 ttattcagcc cttttaactc tagaccaaag tcgggattta cttgtccaag atatcaaaga
      301 caaggtttgt tcccgtagga ttaggaattt gttggctgac ttgattgtag aatgtgaatt
      361 tactcagact gacttggaag acttggaagc tgtgatttca gagaagaaat caagtgctgt
      421 aacagaagta agatgtaatt gtatgtaaag gagacgtcat gttaaatagt attgtaacca
      481 ttatttgtat tgcccttatc gcgtttatct tgttttggtt tttcaaaaag cctgaaaaat
      541 ctggacaaaa agcccagcaa aaaaacggat accaagagat tcgagtggaa gtcatgggag
      601 gctatactcc tgagttgatt gtcctcaaga aatcagtgcc agcccgcatt gtctttgacc
      661 gcaaggatcc ttcaccatgt ctggatcaaa ttgtttttcc agattttggt gtacatgcga
      721 acctgccaat gggggaagag tatgtagtgg aaatcacgcc tgaacaggct ggagagtttg
      781 gctttgcttg tggtatgaac atgatgcacg gcaagatgat tgtagagtag gtggagacta
      841 tgacagaaat tgtgaaagca agcttagaaa atggcattca aaaaatccgt atccgagctg
      901 aaaaaggcta tcatccagcc catatccagc ttcaaaaggg aattccagct gagattacct
      961 ttcatcgtgc tactccttca aactgttata aggaaattct gtttgaagaa gaaggtatct
     1021 tggaaccaat cggcgtagat gaggagaaag tcattcgttt tacacctcaa gaattagggc
     1081 gacatgaatt ttcttgtggc atgaagatgc aaaagggaag ctatatagtc gttgagaaga
     1141 ctcgaaaatc tctatctctc ctgcaacgtt tttggattac tagtatcttt actgtgcctc
     1201 ttgtgattct catgattggg atgttgacag gtagcattag tcatcaagtc atgcattggg
     1261 gaacctttct agcaacaacg cctattatgt tagttgcagg taagccatat atccagagtg
     1321 cttgggccag ttttaaaaag cacaatgcca acatggatac cttggttgcg ctgggaactc
     1381 tagtggctta tttctatagc ctagttgctc tctttgctgg tctccctgtt tacttcgaaa
     1441 gtgctggatt tatcctcttt ttcgttcttt tgggagcagt ttttgaggaa aaaatgagaa
     1501 aaaatacgtc ccaagctgtg gagaaattac tggacttgca agctaaaacc gcagaagtct
     1561 tgagtgatga tagttatgtc caagttcctt tggaacaagt caaggtaggc gacctgattc
     1621 gagtgcgtcc cggtgaaaag attgctgttg atggtgtcgt agtagaaggt gtctctagta
     1681 ttgacgaatc catggtgaca ggtgagagtc tgcctgtgga caagacagtt ggagatactg
     1741 tcattggctc aaccatcaat catagtggaa cgcttgtctt tagagcagaa aaagttggct
     1801 cagagactgt tttggctcag attgtggatt ttgtgaagaa agctcagaca agtcgtgcgc
     1861 cgattcagga cttgacggat aagatttcag ggatttttgt cccagtagtt gtcattttag
     1921 gaatcatgac cttttgggtt tggttcgtct tgctcaggga tagtgtggtc gtgcttggag
     1981 ctagctttgt gtcctctctt ctctacggag tggcggtttt gattatcgcc tgtccttgtg
     2041 ccttgggact tgcaacaccg acagccctta tggtggggac aggacgtagt gccaagatgg
     2101 gggttctcct caaaaatgga actgtcttac aggaaatcca gaaagttcaa actcttgtct
     2161 ttgataagac cgggactttg acggaaggga aacctgtggt aacagatatc atcggcgacg
     2221 aagtagaagt gtttggattg gcagcctcct tggaagatgc ttctcaacac ccactggctg
     2281 aggctatcgt taagcgagcg agtgaagctg gacttgagtt tcaaactgtt gaaaattttc
     2341 aggccttgca cgggaaaggt gtttcagggc gaatcaatgg aaaacaagtt ttacttggaa
     2401 atgctaaaat gctggatggc atggatattt ctaatactta tcaagataaa ctagaagaac
     2461 tagaaaaaga agctaagaca gttgtgtttt tagctgttga caatgaaatc aaaggcttgc
     2521 ttgctttgca agatattcct aaggaaaatg ctaagctagc catcagtcag ctaaaaaaac
     2581 gtggtctccg aacagtcatg ctgacaggag acaatgctgg tgtggcgcgt gctattgcag
     2641 atcaaatcgg aattgaagag gtcattgcag gcgtcttgcc agaagaaaaa gcccatgaaa
     2701 tccataaact gcaagcggct ggcaaagtag cctttgttgg ggacggtatc aatgacgctc
     2761 ctgcccttag tgtagcagat gtgggaattg ctatgggtgc tggaacagat atcgccatcg
     2821 agtcagcaga tttggtgttg acaaccaata atcttttagg agtggttcgt gcctttgata
     2881 tgagtaagaa aacctttcat cgaattctac tcaatctttt ctgggctttt atctacaatg
     2941 ttgtcggaat tccgattgca gcaggagtct tttcaggtgt tggactggct ctcaacccag
     3001 aattggcagg tctagccatg gcctttagtt ctgtatctgt tctgaccagt tcccttctgt
     3061 taaattttag taaaatagac taaaagtaat gactagattt ctttgttata aaacagaaat
     3121 gacaacactt tcaaaactgt attagaatag agaatagaga gttttgagca gatttttaga
     3181 aaagtcagca taaatatgat acagtggaat agtaaaaatt tggagaacgt ttccaattct
     3241 atgtaatcgt attctccaag tttaaaaaaa ttgaaggaga gttatcatta tgactcaagg
     3301 gaaaattact gcatctgcag caatgcttaa cgtattgaaa acatggggcg tagatacaat
     3361 ctacggtatc ccatcaggaa cactcagctc attgatggac gctttggctg aagacaaaga
     3421 tatccgcttc ttacaagttc gccacgaaga gacaggtgct cttgcagcgg ttatgcaagc
     3481 taaattcggc ggctcaatcg gggttgcagt tggttcaggt ggtccaggtg cgactcactt
     3541 gattaacggt gtttacgatg cagctatgga taacactcca ttcctagcga tccttggatc
     3601 acgtccagtt aacgaattga acatggatgc tttccaagag cttaaccaaa acccaatgta
     3661 caacggtatc gctgtttaca acaaacgtgt agcttacgct gagcaattgc caaaagtaat
     3721 tgacgaagcc tgccgtgctg cagtttctaa aaaaggtcca gctgttgttg aaattccagt
     3781 aaacttcggt ttccaagaaa tcgacgaaaa ctcatactac ggttcaggtt catacgaacg
     3841 ctcattcatc gctcctgctt tgaacgaagt tgaaatcgac aaagctgttg aaatcttgaa
     3901 caatgctgaa cgcccagtta tctatgctgg atttggtggt gttaaagctg gtgaagtgat
     3961 tactgaattg tcacgtaaaa tcaaagcacc aatcatcaca actggtaaaa actttgaagc
     4021 tttcgaatgg aactatgaag gtttgacagg ttctgcttac cgtgttggtt ggaaaccagc
     4081 caacgaagtg gtctttgaag cagacacagt tcttttcctt ggttcaaact tcccatttgc
     4141 tgaagtttac gaagcattca agaacactga aaaattcatc caagtcgata tcgaccctta
     4201 caaacttggt aaacgtcatg cccttgacgc ttcaatcctt ggtgatgctg gtcaagcagc
     4261 taaagctatc cttgacaaag taaacccagt tgaatcaact ccatggtggc gtgcaaacgt
     4321 taagaacaac caaaactggc gtgattacat gaacaaactc gaaggtaaaa ctgagggtga
     4381 attgcaattg tatcaagttt acaatgcaat caacaaacat gctgatcaag acgctatcta
     4441 ctcaatcgac gtaggtaaca ctactcaaac atctactcgt caccttcaca tgacacctaa
     4501 gaacatgtgg cgtacatctc cactctttgc gacaatgggt attgcccttc ctggtggtat
     4561 cgctgctaag aaagacaatc cagatcgcca agtatggaac atcatgggtg acggagcatt
     4621 caacatgtgc tacccagacg ttatcacaaa cgttcaatac gaccttccag ttatcaacct
     4681 tgtcttctca aatgctgagt acggcttcat caagaacaaa tacgaagata caaacaaaca
     4741 cttgtttggt gtagatttca caaacgctga ctacgctaaa attgcggaag ctcaaggagc
     4801 tgttggattc acagttgacc gtatcgaaga catcgatgca gttgttgcag aagctgttaa
     4861 attgaacaaa gaaggtaaaa ctgttgtcat cgatgctcgc atcactcaac accgtccact
     4921 tccagtagaa gtacttgaat tggatccaaa acttcactca gaagaagcta tcaaagcctt
     4981 caaggaaaaa tacgaagcag aagaactcgt accattccgt ctcttcttgg aagaagaagg
     5041 attgcaatca cgcgcaatta aataattcct ctcgccgaaa atcaaatatg aaacttgtag
     5101 actttattct ttgattttca tagagcagaa ctttaaaaga tcggagcaat ccggtctttt
     5161 tatggaggag agtaaatgaa tttaaatcaa ttagatatta tcgtttcaaa tgttccccaa
     5221 gtctgtgctg acttggagca tatcttggat aaaaaggcag attatgctga tgatggtttt
     5281 gctcagttta cgattggtag tcactgcctt atgttgtcac aaaatcattt ggttcctttg
     5341 gaaaactttc agtcaggaat cattattcat atcgagattg aggatgtaga ccagaactac
     5401 aaacggttga acgagcttgg tataaaggtt ttacacggac caactgtaac cgattgggga
     5461 acagagtcct tattagttca aggacctgct ggtctagtgc ttgattttta tcgtatgaaa
     5521 taggtcgcgt agtcatttga cgttaacctt agctattttt aaaatagaaa ttgagaatat
     5581 gaactattga aagatcggag caatccggtc tttttatata aagaaattgc atataatact
     5641 catctgcttt caaaaagcat tctagtccat ctccgattaa cgatggactt tatcacctcc
     5701 ttctccaatc cttgtatgac atcttggagt tgattcatga catcttccaa agttcgaaag
     5761 gctttattct taaatccacg tttacgaatc tctttccaca cttgttcaat gggttcatct
     5821 ctggtgtgta tggaggaata aatgcaaaac caatattagt cggaatcttt aaggtacttg
     5881 atttatgcca tatagcattg tctataacga gtaaaaaata atcatatgga taagcttgtg
     5941 aaagctcttc taaaaaggcg ttcatccact cagtattaca tctaccagct attaagaaaa
     6001 atgattcgcc tgtatgggca tcaacagctc cataacaata gcgaaattct cgtatatagt
     6061 gactatggac atgtggacct actcctattg gagaccaaca agatcccagt ttactgattc
     6121 taccgaaacc agcttcatct tggtacatca agcgaacctt atgaaaaggt ctactggttt
     6181 taaagcgctt tcttgtcttc ttgaattgag attttatttt tagatgcgac aatggtttga
     6241 gcgtctgctt tcttaggatg ttctggacgt ggcgtaatat ttcgccaacc atggcgcttc
     6301 aacagttgat agaaggcatc acgtgtgtag gaacgaccta actccttttt ataagcctga
     6361 aataaggcat caattgtaac aaattctcct gcctctgtag ccttcaaatg gcgagcaag
//
LOCUS       DAVLMQ010000081         6157 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000081 DAVLMQ010000000
VERSION     DAVLMQ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6157
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.082"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            231..547
                     /locus_tag="VXF95_002010"
                     /pseudo
     CDS             231..547
                     /locus_tag="VXF95_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            727..1386
                     /locus_tag="VXF95_002011"
     CDS             727..1386
                     /locus_tag="VXF95_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HEV1082493.1"
                     /translation="MKNLTKIKFKENGEFNHFPGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1411..2478
                     /locus_tag="VXF95_002012"
     CDS             1411..2478
                     /locus_tag="VXF95_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082494.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGSLIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2581..3591
                     /locus_tag="VXF95_002013"
     CDS             2581..3591
                     /locus_tag="VXF95_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082495.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3603..5294
                     /locus_tag="VXF95_002014"
     CDS             3603..5294
                     /locus_tag="VXF95_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1082496.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5297..6007
                     /locus_tag="VXF95_002015"
     CDS             5297..6007
                     /locus_tag="VXF95_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1082497.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
BASE COUNT         2066 a          849 c         1173 g         2069 t
ORIGIN      
        1 caggacagtc aaatcgattt ctaacaatgt tttagaagta gaggtgtact attctagttt
       61 caacatacta tattatcgct taccaatatt tgcttttata tttgctaaac tttcagaaaa
      121 aaagttggag tatatgatgc taggtgactg cgtcatgtta gtaaacgaaa tggaaataac
      181 tgatcataga gtagataact tatttgaaaa agggaaaaat gagataaaag atccatgtag
      241 tagatttagc aataggacat ataaaagctt tagaaaaagt atctgaaaaa acagatgttt
      301 atatctataa cctatgctcg ggagaaggca ctagtgtatt acaacttgta aatacatttg
      361 aaagtgttaa taagatccct attccttata aaatagttcc aagacgttca ggagacgttg
      421 caacttgtta tgcaaatgca gacaaagagc atataaggaa ttaaattgga ggacaacaaa
      481 atcgattgaa gacatgtgta gagatacatg gaattggcaa tcaaaaaatc ccaatggcta
      541 taattgatga tactgtctat atgagtgctg tattttggaa aaattactta accttttaat
      601 gaaatgcata tttaatgaaa gataaattaa aaaaaatgtt tgacagcgct tgacaaagga
      661 aacggtttca ttgtataatg taaacatagt gacaccgatg tcaaatataa aaaagaaggt
      721 ctttatatga aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc
      781 cctgggaata cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat
      841 attattcaat cacgttatag agaattacca tttatcgata agtttacttt aactccaagg
      901 aattctattc acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt
      961 tggagcagta atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa
     1021 caacttgaaa tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga
     1081 aaacaaaaca tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt
     1141 cgtacttatg tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc
     1201 catatttcaa ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact
     1261 aaagtcagag cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac
     1321 cgtattgact atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt
     1381 aaataaaata ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta
     1441 cttgcaacgg gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg
     1501 actgcttctt catctgaaga aaaagctgat aaaagtcaag aattagttat ctattcgaac
     1561 tcagtctcaa atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat
     1621 ataaaaatgg ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat
     1681 aatgcagttg cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat
     1741 caaaaattac tagtacagta caagcctaaa tggttagata aaattgatca atctttatca
     1801 gataaagata attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct
     1861 gatgtaaaag aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat
     1921 tcaatttatg gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt
     1981 taccttgatg aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa
     2041 tactttgcaa atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat
     2101 aaagaaagcc caattcaata cggtatgatc tggggttctg gatcgttaat tggacaaaaa
     2161 gaacaaaatg ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa
     2221 caaactatgg ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg
     2281 tttggtcaat cagaaattca agtagaatat agtaaaaaat ttggatctat tcctgcaaat
     2341 aaagatgccc taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca
     2401 caaaatattg actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa
     2461 ttagaatacg tacaataaga aataagagtt attttttatg tccaagtctc tctattattt
     2521 ctaaatttaa ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag
     2581 atgattaaat ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg
     2641 aatttagata tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa
     2701 tcaactactt tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt
     2761 aatggaacag atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa
     2821 tcttatgcgc tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt
     2881 aagaaggtag ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag
     2941 atctctgatc aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg
     3001 gtagcattgg ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg
     3061 tcaaaccttg acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa
     3121 gagttaggta ttactacttt atatgttact catgatcaag aggaagcctt gactttatct
     3181 gatagaattg cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt
     3241 tatcataatt ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc
     3301 gatgaaacag tccacgaagt attattgaaa aatacaagcg ttttcttaga ggataaaaaa
     3361 ggatacattc gattagagaa agttcgattc aatcgtgaaa ctgaacaaga ttttattcta
     3421 aaagggacaa ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt
     3481 tctgaaagtc agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc
     3541 ggagaaagtg tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca
     3601 gtatgcgtca taaattaaat ttaaaagatt ggcttattcg tttaggatta atctggttct
     3661 tagtaacatt tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag
     3721 gagaattttc ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta
     3781 ttatgaacag ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc
     3841 tttgtgttct atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt
     3901 atatgacctc tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg
     3961 gtccttatgg attgattaca aaatttttac aaaatgttat cccttcttta gactctaact
     4021 ggtttattgg gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata
     4081 cattgttttt aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa
     4141 atatgggagc aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa
     4201 ctctatttgc acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca
     4261 tgattgttgg tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga
     4321 tggggaattc tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa
     4381 ttttgcttac tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga
     4441 ctaaagcgcc tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca
     4501 ttgtagcata tggattgttc acagttttca tgcttccact aatttttata gtattatact
     4561 catttacaga tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag
     4621 aaaattatcg cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta
     4681 tttattctat tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg
     4741 tcagaaaaca taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt
     4801 tactaccaag tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc
     4861 ttgtcttgaa tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg
     4921 taaaaatccc attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga
     4981 tggaagatgc agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca
     5041 ttccatttat tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa
     5101 ctgacttcga cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga
     5161 ttcgatctgc aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata
     5221 caattgttct gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta
     5281 aagtaaggaa ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt
     5341 caggattgtt ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc
     5401 ccagcctgca ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat
     5461 gacgaatgaa tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca
     5521 agttatatca ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa
     5581 aattacaggt ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat
     5641 tggagtaggt ttttatgagg gagctctttt agtagccatt tctgtttggg gtgtgatatc
     5701 catgttccaa ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat
     5761 agtagttaaa tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat
     5821 cagaatgacc gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt
     5881 tgatgttccg gacaaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga
     5941 acatcttcga ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat
     6001 tagctgaaat ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt
     6061 taatcatcta atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc
     6121 aattttgatt taggtaaaat agaatatttt gataata
//
LOCUS       DAVLMQ010000082         6084 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000082 DAVLMQ010000000
VERSION     DAVLMQ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.083"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            69..752
                     /gene="rpiA"
                     /locus_tag="VXF95_002016"
     CDS             69..752
                     /gene="rpiA"
                     /locus_tag="VXF95_002016"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HEV1082498.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTSKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKIVATPSKEYIWVVDESKLVDKLGAFKLPVEVVQYGAEQIFRRFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIEDPIVFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QILTSRKEK"
     gene            766..1977
                     /locus_tag="VXF95_002017"
     CDS             766..1977
                     /locus_tag="VXF95_002017"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HEV1082499.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            1979..2521
                     /locus_tag="VXF95_002018"
     CDS             1979..2521
                     /locus_tag="VXF95_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
                     /protein_id="HEV1082500.1"
                     /translation="MTRYALLVRGINVGGKNKVVMAELRQELTNLGLEKVESYINSGN
                     IFFTSIDSKAQLVEKLETFFAVHYPFIQSFSLLSLEDFEAELENLPAWWSRDLARKDF
                     LFYTEGLDVDQVIATVESLELKDEVLYFGKLGIFWGKFSEESYSKTAYQKYLLKVPFY
                     RHITIRNAKTFDKIGQMLKK"
     gene            2537..3346
                     /locus_tag="VXF95_002019"
     CDS             2537..3346
                     /locus_tag="VXF95_002019"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HEV1082501.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            3843..5450
                     /locus_tag="VXF95_002020"
     CDS             3843..5450
                     /locus_tag="VXF95_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HEV1082502.1"
                     /translation="MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEI
                     TEPAQDSPILAPVEETKEEAVTEKPTNTRSLTAEDLVKISKGELHLENDLIDESFYGE
                     KALDLEGDDDQDGIKNKDGKDYLGYNSHPLLADSDGDGLADGEDDNKKEWYVTDRDSL
                     LFMELAYRDDDYIEKILYHKNLFPSLYLDRQEHKLMHNELAPFWKMKKAYYTDSGLDA
                     FLFETKSDLPYLKDGTVYMLAIRGTRVNDAKDLSADLVLLGGNKPAQADDIRKVVGEL
                     AKDISITKLYMTGHSLGCYLAQIAAVEAYQKYPDFYNHVLRKVTTFSAPKVITSRTVW
                     NAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTPLIHNNRDIVTFTGNSRFKHRSRG
                     YFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRFFKKQALPRSSSQPSAEPMENIAL
                     GKQVTQSSTVFGGDARRAVDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINI
                     YNRTDTAQDRLANFDVILLDSSGKEIE"
     gene            5475..5987
                     /locus_tag="VXF95_002021"
     CDS             5475..5987
                     /locus_tag="VXF95_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HEV1082503.1"
                     /translation="MSAQITINHKKVRYVRIELEGYNALSLAEVEVFRFIATNAETAT
                     QVSKPVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVPVDKDGNQVVRSHSWEGNGC
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
BASE COUNT         1874 a         1083 c         1413 g         1714 t
ORIGIN      
        1 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
       61 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
      121 atggaatggt cgttggactg ggaacgggtt ctactgccta ttattttgtc gaagaaattg
      181 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacgacttct agtgtgacca
      241 gtaaacaggc tgaagggctt aacattccac tcaagtctat tgaccaagta gactttgtcg
      301 atgtgacagt cgacggagcg gatgaagtag atagtcagtt taatggaatc aaaggcggtg
      361 gtggtgccct tctgatggag aagattgttg caacgccctc aaaagaatac atttgggtag
      421 tggatgaaag caagctggta gacaaactag gtgcttttaa attgcctgtg gaagtggttc
      481 aatatggtgc agaacagatt tttcgtcgtt ttgagcgagc tggctacaaa ccaagtttcc
      541 gtgaaaaaga tggccaacgt tttgtgaccg atatgcagaa ctttatcatt gaccttgcct
      601 tggatgtcat cgaagatcca attgtttttg gacaagaatt ggaccatgtc gttggtgttg
      661 tagaacacgg tttattcaac caaatggtgg acaaggtcat tgttgctgga cgagatgggg
      721 ttcagatttt aacctcaaga aaagaaaaat agaagggggc ataagatgtc taaatttaat
      781 cgtattcact tggtggtatt ggattctgta ggaattggtg ctgcaccaga tgctaataac
      841 tttgtcaatg caggggttcc agatggtgcc tctgacacac tgggacacat ttccaaaacc
      901 gttggtttga atgtcccaaa catggctaaa atcggtcttg gaaatattcc tcgcgaaacg
      961 cctttgaaga ctgtagcagc tgaaagcaat ccaacaggat atgcgacgaa attggaagaa
     1021 gtatcccttg gtaaggatac catgactggt cactgggaaa tcatgggact caacattacg
     1081 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     1141 ttttcaggac gtaaggtcat tcgtgaagcc aacaaacctt actcaggaac agctgttatt
     1201 gatgactttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     1261 cctgttttac aaattgctgc ccacgaagac atcattcctt tggatgaatt gtaccgtatc
     1321 tgtgaatacg ctcgttcgat cactcttgag cgtcctgccc ttcttggtcg catcattgct
     1381 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     1441 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     1501 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     1561 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     1621 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     1681 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     1741 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     1801 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     1861 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     1921 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     1981 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     2041 ggcggagctt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     2101 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     2161 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     2221 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     2281 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     2341 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctggg ggaaattttc
     2401 tgaagaatcc tattctaaga ctgcctatca gaagtacttg ctgaaggtgc ctttctaccg
     2461 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     2521 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     2581 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     2641 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     2701 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     2761 cttggctctt caagggcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     2821 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     2881 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     2941 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     3001 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     3061 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     3121 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     3181 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     3241 ggccggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     3301 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
     3361 aaggggaagt gcctctgttt tttcaggatt gactgcctat ccggattaaa gaagaaacag
     3421 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
     3481 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
     3541 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
     3601 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
     3661 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
     3721 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
     3781 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
     3841 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
     3901 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
     3961 caaaagtaga gataacagag ccagctcaag actcacctat tcttgctcct gtagaagaaa
     4021 ctaaagaaga agctgtgaca gaaaaaccaa caaatactcg ttctctaact gcagaagatt
     4081 tggtgaagat ttccaaaggg gaattgcatt tagaaaatga tttgattgat gaatctttct
     4141 atggtgaaaa agctcttgat ttggaagggg atgatgacca ggatggcatc aaaaacaaag
     4201 atggtaagga ttatctagga tataacagtc atcccttgct agcagacagt gatggggatg
     4261 gtttggcaga tggggaagat gataataaga aagaatggta tgtcacagac cgtgattctc
     4321 ttctctttat ggagttagct tatcgagacg atgattatat tgagaaaatt ttatatcata
     4381 agaatctttt ccctagtctc tatcttgacc gtcaagaaca caaactcatg cacaatgaat
     4441 tggctccttt ctggaagatg aaaaaagcct actatacaga tagtggcttg gatgctttct
     4501 tatttgagac caagagcgac cttccttatc tcaaagatgg aacggtgtac atgttggcta
     4561 ttcgtggaac gcgagttaat gacgccaagg acttgagtgc agatttggtt ttattaggtg
     4621 gaaataaacc agctcaagcg gatgatatcc gcaaggttgt tggggaatta gccaaggata
     4681 taagtattac taagttgtat atgacaggtc attctcttgg atgttaccta gctcagattg
     4741 cagcggttga agcttaccaa aaatatcctg atttttataa ccatgtattg aggaaagtga
     4801 caactttcag tgctcctaaa gtgattactt ccagaactgt ttggaatgct aagaatggtt
     4861 tctgggatgt tggtttggaa agtcgtaaat tagctgttag tggaaaaatt aagcattatg
     4921 tggttgataa tgacaatgtt gtgactccct tgattcataa taatcgtgat attgttacat
     4981 ttacaggtaa ttcacgcttt aaacaccgtt ctcgtggcta ttttgaaagt ccaatgaatg
     5041 atattcctaa ctttaatatt ggtaaacaag ctaccttgga taaacatggt tatcgtgatc
     5101 cgaaattgga taaagtgcga ttctttaaga aacaggctct gcctcgatct tctagtcaac
     5161 caagcgctga accaatggaa aatattgcct taggaaaaca ggttactcaa agttcgacag
     5221 ttttcggagg agatgctaga agagctgtgg atggcaaagt cgatggtaac tatggtcaca
     5281 attctgtcac tcatacaaac ttccaatcta agccttggtg gcaagtagat ttggctaaag
     5341 aagaaaccat tcgccaaatc aatatttaca accgaacaga cactgcccag gatagattgg
     5401 caaactttga tgtcattctt ttagacagtt ctggtaaaga aattgagtaa aaacgtataa
     5461 catctcctaa agatgtgtca gcacaaatta cgattaacca taaaaaagta cgctatgttc
     5521 ggattgagct agaaggctat aatgccctca gtcttgcaga agttgaagtt ttccgcttta
     5581 tagctacgaa tgctgaaacg gcgacacaag tttctaagcc agttcaacca atcagtcaga
     5641 ctcctgtgaa agataaaaca ttgacaattc aacacagtgg agcttacatt gcccgctact
     5701 ccataacttg ggaagaagtt ccagtagata aagatggaaa ccaagttgtt cgtagtcatt
     5761 cttgggaagg aaacggttgc aaccagactg caggttttgt cctcaacctc ccaatcaaag
     5821 aaaatatgag aaatctgcga gttaagattg agaaaaagac gggcctacta tggaatagat
     5881 ggcaaacaat ctatgaaaac agaccaattt tagctcaacc ccaccgtaaa attacccatt
     5941 ggggtacgac attgaattcc aaggtgagtg acgatgatgt cttgtaatct gatggtacaa
     6001 tgacagttag tttgtctagt ttataagaaa gtactacctg agcttgaata gaactcaggt
     6061 agctctctat gaaagaacaa aatt
//
LOCUS       DAVLMQ010000083         6035 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000083 DAVLMQ010000000
VERSION     DAVLMQ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6035
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.084"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(203..1708)
                     /gene="pyk"
                     /locus_tag="VXF95_002022"
     CDS             complement(203..1708)
                     /gene="pyk"
                     /locus_tag="VXF95_002022"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HEV1082504.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATSSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
     gene            complement(1767..2774)
                     /gene="pfkA"
                     /locus_tag="VXF95_002023"
     CDS             complement(1767..2774)
                     /gene="pfkA"
                     /locus_tag="VXF95_002023"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HEV1082505.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEADFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            complement(2857..5958)
                     /locus_tag="VXF95_002024"
     CDS             complement(2857..5958)
                     /locus_tag="VXF95_002024"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HEV1082506.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDDQEVNLRFLALSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQERFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YELSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLALFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDPVLEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVLEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQIMLNSANSDYVTDALEAGFEVAPLSINTIPYH
                     DKIANKAIYLGLKSIKGVSNDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
BASE COUNT         1759 a         1365 c         1053 g         1858 t
ORIGIN      
        1 actttgaaaa cttcaaaaaa cggattttta tcgctttgaa catcaaaaaa gaaaggacga
       61 aatttgtcct ttctcgagct tagctgactt caacccacta cagttgacaa agagcccatt
      121 atgaaagttt tgccccctgg acaaaaaaaa gagcccatca tacaggctag aaagctagat
      181 atgataggtt tttatatttt tcttaacgta ctgtgcggat acgcattgtg tttgtgcgaa
      241 cagcttctcc tactggcaca ccagcaacga taacgatatc atcgcctgac tcaacgagac
      301 ctgcttctac cgctttacgt tcagcgattt cgaacatatc gtcagttgaa gatggagcat
      361 ctgtcaacat tgggataaca ccccagttca acatcaagcc acgttctgtc aattcgtcaa
      421 atgtcaatgc taagatgtca gcatttggac ggtatttaga aatcaaacgt gcagtatgac
      481 ctgtcttagt aagagttaca accaatttga tatccattga gctagtagca tctttaacag
      541 cagaagccat tacttctgtc ttagagttac gctcaaatga atctgaatca agacgtccgt
      601 attcattaag aagagcttga gcgttcttgt cgattgtagc cattgtagtt actgactcga
      661 gtgggtattt accgtttgca gactcgcctg acagcattgt agcgtcagtt ccgtcgataa
      721 cagcgttgaa tacgtctgat acttctgaac gagttgcacg tggtttttca gtcattgttt
      781 caagcatgtt tgttgcagtg ataacaactt tacctgcagc attgactttc ttgataatca
      841 ttttttgata aactggaacc atttcgaacg gtacttcgat acccatatca ccacgagcaa
      901 tcataatacc atcagctgct tcgataattt cgtctaagtt atcgatacct tgttggtttt
      961 cgattttagc gaacaattga acatgtccgt ttccagtttc ttcacagatt gcacgaactt
     1021 cgttcacatc ttttgcagta cgtacgaatg aaattgcgat gaagttgata ccttgttcaa
     1081 gaccgaaacg gatatcgtcg ttatcgcgtt cagcaagagc tgggaaagga attttagtgt
     1141 tagggatgtt cacacctttt tgtttagcga tgataccatc gttttcaact tcaacttcaa
     1201 attcacgagt tgcatcatct ttagcaacca cacgaagacc aagtttacca tcgtcaacca
     1261 aaacttgacg accaacttca acatcatcat agatatcaag agcaccagca acgttcaacg
     1321 caatcacttc acgagttgat ttgattcctt gtttagttgc aacacgaatt ttttcaccag
     1381 ttttgtatga atattcttta gcttcacctt cgaacaattc tgtacggatt tcaggtcctt
     1441 ttgtatcaag aaggaaacca acttttttac ctgcaatttt ttccgcaagt ttaacagttg
     1501 ccatacgctc accttgttct tggtggtcgc cgtgtgagaa gttgaatcgg aatgtgttag
     1561 caccagcttc aatcaattta gcaatgtttt tagctgaagc ttcaacatca agtttttcac
     1621 cccagtatcc gtcctcaccg aattttttac caccacggat ttctaccgca ggacccaaag
     1681 ttgcaacgat ttttacacgt ttgttcatga tttttgtgac tcctttatat atatgacctt
     1741 tttggtctta ttaactaaat tgtaaattat gacaagctct tattcaagct agatagctca
     1801 atatcggctt tgtgtgggtt gttaaccaca atcttacctt ctgcagtaag gctaaacaat
     1861 gccccttctt ctgcagtacc aagaattgga ttttcaacca ttttttcgtt acgaatacca
     1921 accgcaacac caccgatacc ttctttaaga agtttaacag catgtgcacc catacgtgac
     1981 gccaaaacac ggtcacgcgc agttggagaa ccaccacgtt gaatatgtcc aagttctgtt
     2041 acacgaaggt cgcttgtatc tccagcttct ttaagttttt gaccaaattc agccgctgac
     2101 atcacacctt cagctaagac gatgatattg tgttttttac cacattcata accagctttg
     2161 atgcttgcta cgatatcttc catcttgaag tctgcttcag ggatgatgat ttcatcagca
     2221 ccagttgcaa taccagccca aagagcgata tcaccagcgt tacgtcccat aacttcgatt
     2281 acaaaagtac gacggtgact tgatgatgta tcacgaatct tatcaatagc gtccatggca
     2341 gtagtaaccg ctgtgtcaaa accgattgta aagtcagtac caacgatatc gttatcgatt
     2401 gtacctggaa gaccaatagc tgggaagcca tgttcagtca aacgcatagc gccgtggtaa
     2461 gatccgtcac caccgataac aactacacct tcaattccgt gttttttcaa ttgctcaatc
     2521 cctttaagtt gcccttcaag ttgagcgaac tctggataac gagctgagtg aagaaaagta
     2581 ccaccacgag aaatgatgtc tcctactgaa gctgcatcta ggggatgaat ttcaccagca
     2641 accataccag catatccgtc atagatacca aacacttcca ttccttctga aattgcttga
     2701 cgaacaactg cacggatagc agcgttcata ccaggtgcgt ctccgccact agtcaaaaca
     2761 gcaatacgtt tcatattggt ttatgctcct ttttctttta acattcttct tgattatatc
     2821 acatttgatt ttaaaattct tctattttcc gtatttttag cgataaatcg ttttcataac
     2881 gatttcattc aatttctcct ctaattcatt ggatttagct acaaaatgat ggggagaaac
     2941 gatggttttc tgttcctctt cataccggat gatgactggg attgggcctt taaattgttc
     3001 taaaatacgt gaaatttctt gatccgattc atgatttttc acctgtatcc aaaagcgttc
     3061 agcaactgct tctcttattt cttgtgcaat catttgcaga cggccatcac gtgattgtat
     3121 ttttcctttt acatagtaga aggctccctc ttttatttcc tgtccgacct gacgatataa
     3181 gtctgaaaag agagtgacat ccaatttttt cttactatca tctgcctgta agaaggccat
     3241 attttcaccc tttttggtac gaatcacttt tattttctga acttcaacca aaataatagc
     3301 atagctattt tctgacaaat ttccgattgg ggtaatcggg taaatagcct tacttgcaat
     3361 agcttgtagt ggatgtttgc tgacacctat ccctaaaagc tcttgttcca tataaaattt
     3421 ttcttgttcc gtccaatctt ccgattcctg ccaactataa atagcatctc caaacaaact
     3481 tcccaactct ttcacaaatt caaatagatt agctaagtta ttaaatactt tttgacgatt
     3541 tttttcaaat gaatcgaaaa gaccaacttt taccaaaggt tctagcagag gaagtttcag
     3601 ataattctca ggtaatttag ctataaaatc ttcaatgtta gaataaggtc tatgttcaat
     3661 aatccagaga gctaaatcat tactgactcc tttaatggat ttcaaaccta gatagatggc
     3721 cttgttggca attttatcgt gatagggaat cgtgttgatg gacaatgggg ctacttcaaa
     3781 acctgcttct aaggcatctg ttacataatc actgttagca gaattcaaca taatctgata
     3841 aaatatggct ggataatgtg ttttaaaata agccaactgg aaggccaagg ctgagtaggc
     3901 gtaggcgtgt gacctgttaa aaccatagcc tgcaaacttc tccagaacat caaaaacctg
     3961 ctctgctttt tccgcagtat ggcctgcttc tatggagcct tgaataaagg aagccctcat
     4021 ctcatgcata gcagaagcat cctttttacc catagctcga cgcaaaatat cggccttccc
     4081 aagactaaat ccagcaaatc gctgggcaac ctgcataacc tgctcctgat agagcattat
     4141 gccgtaggtt ggagccaaaa tatcctccag tactggatcc agaacagtca cttcttcctg
     4201 cccatgcttt cttgccacaa aattattgat atagtcacta gcacccggtc gatttagaga
     4261 agtagtcgcg acgacatctt caaaacagac tggttgcaca cgcttaagca gacgaatggc
     4321 acctggttgc tcaaattgaa agataccttt tgtattacca gaggcaaata aagctaacgt
     4381 ttctttgtct tctaaatcga tttcttcaat tttcagatga ataccttctg tttcagcaag
     4441 caactcttgc atcttctgga caaaggtcaa atttcgtagt cccagaaagt ccatcttcaa
     4501 aagtccgcta gcctcaactc catgagcatc atactgagtc agtggaattt catcaccata
     4561 ctttagagga atgtagttgg ttaaatcttg gtcactaatt acaacaccag ccgcatggac
     4621 agaggtttgc cttggatagc cctctatctt gcaagcaatc tcaaaagctt tttggtattc
     4681 taacttacta ttgatttgct gacgaaactg gagattgccc tcataggccg acttaagatt
     4741 gtcacgaaaa ctgattttct tagtaattgc agataattca tactctggca caccaaagcg
     4801 tttcaagaca tctcgaagag cttgcttggc tccaaaggtt gaaaaagtaa cgatttgtgc
     4861 cgcatgttta ctaccatatt tattaccaac atatctgata aaatctggac gataaatatc
     4921 tgggatatca atatcaatat caggcatggt atagcgttca cgattaagaa agcgttcaaa
     4981 aatcagattt ttctctactg ggtcaatccc cgtgatgtct aaggcataag aaaccaaact
     5041 gcctactgca gaaccccttc ccattcccat ataatagcca ttcgatcgtc caaaacgcaa
     5101 caaatcccaa acaaccaaga aataatcatc aaagcccata tcatgaataa cagacaattc
     5161 ttggtctagt ctatcttgat attctttact agtcaacccc ttctgaacaa gccccagttc
     5221 agcacgctct ctcaactcct ctactgctgg tctagctgga ttaaaacgag gcagtttcag
     5281 actagtatcc aagtcgtaag aaatgcctga aataagcttt tctaaattgt ccaaagcttg
     5341 cggaaaacgc tcttggaata gtttctctaa agaacttgct gatataaaga catcttgtct
     5401 cgaacgcaag ggaacttctc tgagcggtag attttcttta atcgctgtta aaacttgaag
     5461 aacttctcta tccctgcttt caaaagcgtt gacccgataa agaggtaaga taggatgatg
     5521 aaattcgctt gctagtgttt ctggataaac ccctatatag taatcacagc ctagttctaa
     5581 cgactcaact ctatcaaaat aaggcacaat gaccgcgata tcctccaggt actgggacag
     5641 gactgaccaa gttttctccc cctgcatctt ggctgtcgaa agcttcatca actgctgata
     5701 gcccacacta gatagagcta aaaagcgcaa attcacttcc tgatcatcta caaacactgt
     5761 catttcaagc cctagcaaag gatgaatgcc gtattttttt gtaatctcta gaaagtcgaa
     5821 agcgccataa agattgtcaa tatccatcat agccaaatga gtgtagccgt attctttagc
     5881 tgctctcaca tacttttcga tcgaaatgac gctttccata aaactataga ctgtttttgt
     5941 atctagttgt gcgatcaatt tacacttctc ctctatcctt ctcactatat tataccattt
     6001 tcacctataa atggcttctc ttgagaaaaa tttca
//
LOCUS       DAVLMQ010000084         5763 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000084 DAVLMQ010000000
VERSION     DAVLMQ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5763
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.085"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            109..636
                     /locus_tag="VXF95_002025"
     CDS             109..636
                     /locus_tag="VXF95_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HEV1082507.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
     gene            648..1163
                     /locus_tag="VXF95_002026"
     CDS             648..1163
                     /locus_tag="VXF95_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HEV1082508.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(1160..1627)
                     /locus_tag="VXF95_002027"
     CDS             complement(1160..1627)
                     /locus_tag="VXF95_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HEV1082509.1"
                     /translation="MSRSQLTILTTICLIEDLETQRVVMQYRAPETNRWSGYAFPGGH
                     VENGESFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVVCYKATEFSGTLRS
                     SDEGEVSWVQKDQIPNLDLAYDMLPLMEMMESPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(1680..2189)
                     /locus_tag="VXF95_002028"
     CDS             complement(1680..2189)
                     /locus_tag="VXF95_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082510.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRLFSQKYPENTLIAIGDLKVVGFISYGNFRDETIQAGEIIALYVLKDYYGKGIAQK
                     LMKAALTALDHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SKIILKSRS"
     gene            complement(2155..2718)
                     /locus_tag="VXF95_002029"
     CDS             complement(2155..2718)
                     /locus_tag="VXF95_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082511.1"
                     /translation="MIYLRKLKREDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKQTRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            complement(2728..4716)
                     /gene="uvrB"
                     /locus_tag="VXF95_002030"
     CDS             complement(2728..4716)
                     /gene="uvrB"
                     /locus_tag="VXF95_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HEV1082512.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVVAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            complement(4793..5746)
                     /locus_tag="VXF95_002031"
     CDS             complement(4793..5746)
                     /locus_tag="VXF95_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082513.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLASYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
BASE COUNT         1692 a         1306 c         1036 g         1729 t
ORIGIN      
        1 actataactt ttaactaaaa aatgatctat aaacccaagt aaattcttgc tttattgtct
       61 ggtttattgt accatactag tgtatatgca gttaaaaagg agattcttgt gaatacacgg
      121 aaaaagacac aatttatgac aatgacagcc cttttaacgg ctattgcgat tttgattcca
      181 attgttatgc ctttcaagat tgtcattcca cctgcttcct atactttggg gagccacatc
      241 gctattttta tagccatgtt cttgtcgccc ttgatggcag tttttgtcat cctagcctct
      301 agttttggat ttttgatggc tggctatccc atggttatcg tttttcgggc cttttcccat
      361 atatcttttg gtgctttagg agctctttac ctacaaaaat tccccgatac cctagataaa
      421 ccaaaatctt cctgggtttt caattttgtt ttggctgttg ttcatgccct tgctgaagta
      481 ttagcctgtg tcctttttta cgcaacttcg ggtaccaatg tagaaaacat gttctatgtt
      541 ctatttgtac tagttggatt tggcacaatt atccatagta tggtagacta tacattagca
      601 ctagctgtct ataaagtgct tcgaaaacgc cgttaaaagg aaaagctatg acaaaagatc
      661 gcaaacaagc cctgctccaa ctcttgaaag aagctcctaa agcccttaat ggccaaagtt
      721 tggcggaaca ttttcatgtc acacgtcagg tcattgtgca ggacattgca attttgagag
      781 ccgatggcgc tcctatccta tccaccaatc gtggctacat ctataagcaa attgatacca
      841 atccttatgt tcacaaactt ttcaaagtga aacatgaagt tgaagaaatc ggtcaggaac
      901 tccttgctat tgtcgataat ggtgggcatg tccagaatac cttgattgac catcccgttt
      961 atggagaaat tgaaaccttg cttaaactgt cttgtcgcag agatgtgcaa cattttctag
     1021 aacaagtcga gcattctgac tttagacctc tatctgaatt gacagatggc atccattacc
     1081 acctagtcga agccgaaaca caacaagacc tccactatat cgaggaggcc ttggatcagc
     1141 taggttattt agtaaaagac tagaagattt tcttctccca atcatcttct gtacggcgag
     1201 ggtagaaaaa ttcagatttg tctggagatt ccatcatctc catcaaaggt agcatatcat
     1261 aggccagatc taagtttgga atctggtctt tttgcaccca agaaacttct ccttcatctg
     1321 aagagcgaag ggtaccagag aactcagtag ccttataaca aacgacaata tagcgcccac
     1381 ctgtatctag tggccaattt ttaatgccga caagttgagg attttggata gtcaaccctg
     1441 tttcttcata tatttcacga atgacagact ccgcgaaaga ctcgccattt tctacatgac
     1501 ctcctggaaa ggcataacca gaccagcgat tggtttcagg agcgcggtac tgcatcacca
     1561 cgcgctgcgt ttcgaggtct tcaatcagac aaatggttgt taaaatcgtt aattgggaac
     1621 gggacataaa tttactcgct ttctaattta ttaaattttc agacttggta ccagtgccat
     1681 tagcttctac tttttaaaat tattttagaa tagaatacca ttcgtttttc ctttataggc
     1741 tttccaagtt caagtatctt ttcttgtcca tcaaaagtaa aacccatttt ttgatagaaa
     1801 gcaatggctc gcttgttatc tttcaatacc cataagaaaa tttcagaaaa atgatcaaga
     1861 gcagtcaaag ctgctttcat taacttttgt gctatgcctt ttccgtaata gtcttttaaa
     1921 acatataaag caataatttc accagcttga atagtctcat cacgaaagtt accataactg
     1981 ataaaaccaa ctaccttcag atcacctatc gcaatcaatg tattttctgg atacttttga
     2041 ctaaagagtc gacatctttc taatgtcatt gtctcctgaa attctgcagg caaaaggtca
     2101 tcataagcct ctctccacgt ttgccagtga acgagggatt taccttctat ctcttcagga
     2161 gtttccattg atttgataat aaccgtcatt tattttctcc cagtcttctc tcaaaatacc
     2221 atatttaata ctatcaaaat atttaccttg ataataacga acttttggaa tatgagcttc
     2281 ttttttcatt cttaattttt cagcaagttt catcatacca agattccctg accaagttgt
     2341 caaacccaga tgctccaact ccaagtaatc ctgaaacgtc ctatctatcc actgcaacat
     2401 agcaactttc ccaataccag tgttccagaa ttttttatca taaataccaa ttcccaattc
     2461 catccatctt gtttgtttac atacccaata acgcgaaaca gtcccaacta gtttatcatc
     2521 aacaaaaata ccaaggcgat ttgagttgct taaaatggat tctgattttt gtagttcgaa
     2581 ttctttaaaa tttgaaaaat actgataatc atcataatag ggagcatcat actgtttcca
     2641 aactggatta agttgtgaat aagccatttc ccataaagac atcaaatctt ctctctttaa
     2701 ctttcttaaa taaatcatac tattccccta atccaaggcc ttgacttcca acatcatatc
     2761 acggatctga gccgccagtt caaagtcaag cacttcgacg gcttcttgca tttgtttttc
     2821 tagtttcttg acgagttctt tgcgctcttg tttgttgagg ctattgatgt cgacttcctt
     2881 gtcctcttcc ttagcaactg ccttggtcac ggcaatcagg tcacggattt ctttcttgat
     2941 tgtctgtggt acgataccat gctcttcatt ataggccatc tgaattttcc gacggcgggc
     3001 agtttcatcg atagcacgtt gcatagactg ggtaaccgtg tctgcataca tgatgacatg
     3061 gccttcactg ttacgagcag cacgtccaat agtctggatg agtccacgtt cgttgcgaag
     3121 gaaaccttcc ttgtcagcat cgagaatagc tacgaggctc acttcaggaa cgtcaattcc
     3181 ttcacggagc aggttaattc cgaccaagac atcaaagaca cccaagcgca ggtcacggat
     3241 aatctccgtc cgttccaagg tcttgatatc cgagtgcatg tacttgacct tgatgcccat
     3301 ttccttgaaa tagtcggtca agtcctctgc cattttcttg gtcaaggtgg tgataaaggt
     3361 tcgttcattc ttttcaacac gggcattgat ttcacctaag agatcatcaa tctgtcccat
     3421 agtcggacgg acttccacct caggatccaa aagccctgtc ggtcgaatga tttgctcaat
     3481 caccgtctcg gtctgttcat tttcatagtc accaggtgtc gctgaaacgt aaacaatctg
     3541 atgcacatgg ctttcaaact cctcacgacg gagaggacga ttgtccaagg cagacggtaa
     3601 acggaaacca taatttacta gcatttcctt acgcgaacgg tctccattgt acatgccttt
     3661 tatttgtccc atagtcatat gactctcgtc aatcataatc aaaaaatcat ctgggaagaa
     3721 gtcgagaagc gtataaggag gctcaccttc actacgtcca tccatgtggc gagaataatt
     3781 ttcaacccca tttgtatagc ccatctcgcg cagcatttcg atatcgtact ctgtccgttg
     3841 tttcaagcgc tgggcttcaa gcaatttacc ttccttctca aagacagcta actgctcttc
     3901 taattctgct tgaatcttgg caacggcaac ttccatatgg tcgtcattgg tcacaaagtg
     3961 agtagctggg aaaatcgcca aatgatccac ttctcccaac acctgacctg tcagagcctc
     4021 aacttcacga atacggtcaa tttcgtctcc aaaaaattct actcgaaagg catgttcatc
     4081 tcgggaagct gggaaaatct ctaccacatc cccacgaacg cgaaatcttc cgcgttggaa
     4141 atcaatatca ttacgttcaa actgaatatc gaccaagtca ttcaagagtt tatcacgaga
     4201 aatctctaga ccaggacgga gactaacgac actatcagcg tattccttgg gcgaacccaa
     4261 accatagata caagagactg aggccacgac aataacatca ttacgctcca aaagggctga
     4321 ggtagctgag tggcgaagct tgtcaatctc gtcattgaca gaactatcct tctcaatata
     4381 ggtatcgcta gaagggacat aggcctctgg ctggtaataa tcatagtagg atacgaaata
     4441 ctcaactgca ttttcaggga aaaattcctt aaactcccca tagagctgac cagccagagt
     4501 tttattgtgg gcaacaacca gagttggttt attgacttta gaaatgacct gactcatagt
     4561 ataggtcttc cctgttccag tcgcccccat cagaatctga gctttttctc ccccctcaat
     4621 gttatccacc aactgctcga tagcttgggg ttgatctcct gatggttgat attttgatac
     4681 tagtttaaat tgattatctg taatgtgatt gatcataaga atcctctctc catgtgctat
     4741 tcctatttta gcatacttat agtattttca cgaagaaaag gacggaccga agtcacatcc
     4801 tttcattttc tttctttaat ttattagcaa gatagacaat cagcagtagt aataccagac
     4861 ttgtcataat ggaaccttct atgccaaaag aaccacctga tagccaatct tgattgcctt
     4921 gtggtaaaaa ggtcatcaga gacgttcctg acggttgacc actaactaaa atcccaaaga
     4981 gattaccctg agcaaaattc caagcaccat gaatacctgc aacaccccaa actgtatcag
     5041 ttttgagaag ataaagagcc atggcaactc cgaataaaaa gagatttact agagatagag
     5101 gggtgaggcc agaattgccc atatgaagca gggtaaagaa caggctagat ataagaatag
     5161 ctagttttag attggttctt gaggccaatt gaggaagtag ccaagcacgg gccaccactt
     5221 cttctgctgt cccctgtaaa atccaaaatg ggatagtaaa gacgacaaag gcaagagaat
     5281 aaggattcaa gtgaatggat tccaaacgat attgacctaa gaccactaaa cctaacaagg
     5341 tcagaagaaa aagtgccaag cctagactaa atcctttcag aagattgctg aggaaattct
     5401 ctctataaaa tcccaaggtt cgaataggtc ttttctcaac ttttcttgtc catctgaaca
     5461 cagtgttaag aataaaacca aaggccagta atcctaaaat taaacgaaag tcacttgttt
     5521 tatccgtcaa gctctgatgc aaggtctgca agtagcttgc aagattttga ccagcctctc
     5581 caaaatttct agcaagtccg atgagagcta acaagccaat accatacaaa gtaaaagcca
     5641 caaactctcc tatgaagaca aaaacaaagg ctaacaaggg gcttgtgtaa atgtttaaac
     5701 tcatttttga agcttggaag tctttaaata ttcttttgtt cttcatatcc ccgtcctctt
     5761 ttc
//
LOCUS       DAVLMQ010000085         5635 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000085 DAVLMQ010000000
VERSION     DAVLMQ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5635
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.086"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..315
                     /locus_tag="VXF95_002032"
     CDS             1..315
                     /locus_tag="VXF95_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082514.1"
                     /translation="MNILEEKLGYGTNTLYRLKRSNPSSKVLKEIADYFNVSADYLLG
                     RTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNEDDIDFITSVLSAHFKSKG
                     ER"
     gene            315..548
                     /locus_tag="VXF95_002033"
     CDS             315..548
                     /locus_tag="VXF95_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082515.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            548..811
                     /locus_tag="VXF95_002034"
     CDS             548..811
                     /locus_tag="VXF95_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HEV1082516.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            824..1204
                     /locus_tag="VXF95_002035"
     CDS             824..1204
                     /locus_tag="VXF95_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HEV1082517.1"
                     /translation="MTLAKLCEEYQVELCLFDGSNWHSSGFYNPDTNVLAIDHNLAPE
                     QQIQVALHELGHKDHTRSEYQNARLRCENEADRNMIHHLVKDALESLDDPTEFDYLKF
                     MSYYNLKTMTNEVMVKEEYLALVN"
     gene            1242..2054
                     /locus_tag="VXF95_002036"
     CDS             1242..2054
                     /locus_tag="VXF95_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HEV1082518.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            2228..3376
                     /locus_tag="VXF95_002037"
     CDS             2228..3376
                     /locus_tag="VXF95_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HEV1082519.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(3618..4904)
                     /locus_tag="VXF95_002038"
     CDS             complement(3618..4904)
                     /locus_tag="VXF95_002038"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HEV1082520.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDSFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(5135..5371)
                     /locus_tag="VXF95_002039"
     CDS             complement(5135..5371)
                     /locus_tag="VXF95_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HEV1082521.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRKDFIVYHYRVAYRLYLEKLVMNRGFISC"
BASE COUNT         2036 a         1154 c          933 g         1512 t
ORIGIN      
        1 ataaatattt tagaagaaaa acttggttat ggaactaata ctttatatcg attaaaaaga
       61 agtaatccta gttcaaaagt tttaaaagaa atagctgatt attttaatgt aagtgctgac
      121 tacctactcg gacggacaga taatcctgct atcgctggaa gtgatgaatt tgctcaagta
      181 aatggacaaa tcatagactt acgcaaagca gcagccaaca ccatgttatt tgacggaaaa
      241 ccactaaatg aagatgatat cgacttcatc acatccgttc tatccgccca cttcaaaagc
      301 aaaggagaac gctaatgact atcacgatca atttcacaga aaaaaactcc tacatcacgg
      361 actacctaac caaacacggt atcgacacaa caaccatgga ttttgacgac ttcatggtac
      421 tcatggaaga tatcgaagac gcacgagcag ccgaccaagc ctatatggag tatttagccg
      481 acccagctac ttataccatg gatgaggtct tggatgaact aggactatct cgagaggata
      541 ttgcttaatg tatcggctag atattgataa aaaagctctc aagcaactta aaaaactaga
      601 taccccaacc agaaaacaaa tcctatcctg gcttgctaaa aacattgaaa acacgaccaa
      661 tccacgacaa cacggaaaag cactaaaagc caaccttgca ggttactggc gatacagagt
      721 agagaattac cgcatcatct gtgatatcca agacgataaa ctagtcgtcc tagccgtgga
      781 aatcgcccac cgcagagatg tttataaata acgaaggaga actatgacac tcgctaaact
      841 ctgcgaagaa tatcaagtag agctttgtct cttcgacggt tcaaactggc acagtagcgg
      901 tttctacaat ccagacacaa acgtactcgc tattgaccac aacttagctc ctgaacaaca
      961 aatccaagtc gccctacacg aactcggaca caaagaccat acacgctcag agtaccaaaa
     1021 cgctcgccta cgctgtgaaa acgaagctga taggaatatg atccatcatc tcgtgaaaga
     1081 cgcactagaa agcttagacg accccacaga gtttgattac ctcaaattca tgtcttacta
     1141 caatctaaaa actatgacta atgaagtcat ggtcaaggaa gagtacttgg cattagtaaa
     1201 ttaaaaattg cattgaagat atttatatag aggggaaata tatgcaaaag actgttgaaa
     1261 aaatattatt cagagtcgct ggagtgacaa aatataaaaa agcagtaaaa gaagcttgca
     1321 atatgattgc tgaagataac ggaatcccag aatatgcaaa gtactatagc aatttatcaa
     1381 ctaaggaact tagagaagaa cttgaagaat atggtctgaa agttttcaaa tatcaagatt
     1441 tagacttttt caatattgag ctcgttccag aagtagataa tagatatgat cctaatgcta
     1501 taaaagtttt gatatttgat aatcatgtag gatatgttcc tgcaaccatt gctaaaacaa
     1561 tacgaaaata ttttgataat aaaaaatata actttgtaat agagggagag ataaaaggtg
     1621 gcccatataa agaatgggac gagtatgaag aaaaagttgt cacaaataat gatttggatg
     1681 ttggttttga aatttacctt accattgttg attcttcaca aaaagaagta attcagagcg
     1741 aatcatctga gataattgat gataacattt ccaataaaga agttacggaa actgaagcta
     1801 ttgaaactaa aacaactgaa actgaacata ttgaacaaaa tattgttagt gacagtgtcg
     1861 ctgatatagt aaacgagatt aatctttcag aaacatctcc taagaaaaaa cttcctgcca
     1921 ataaaatcat attttcagca ctgtatcttt tcttagtctt ttttggagtt gttggtattc
     1981 caatcgctcc attccttgca gtccctttga cagcttggag tttgtataaa ctatacaaac
     2041 tattcagaaa ataaaaaaaa gccccacaat cgccctcgcc aaagtttgat tgtgaagctt
     2101 acccttataa aaaatcagcc attaaaaagg cctcttttct ataccctatt ttacaccatg
     2161 aaaggggtga tgtcaatatt ctcaatgttt agaccttgtc cagaagccga taaacaagga
     2221 gaatacaatg aaatataata aaacaaaata cccaaatatc tattactatg agactgctaa
     2281 aggcaagcgt tactatgtca gacgttcttt tttcttccga ggtaaaaaaa gagaaaaaag
     2341 taaaagtggt ttcacaactc tccctcaagc tcgtgcagcc ttggtagagc ttgagcaaca
     2401 aatccaagaa caagaattag gtatcaatac gaatctaacg cttgatcaat attgggatat
     2461 ctattccgaa aagagattgt caacagggcg ctggaatgac acttcctact acctcaatga
     2521 caatctctat aagaaccata tcaaggcaaa gtttggttct atcctgctta aaaatttgga
     2581 tagaaatgag tatgaactat ttatcgctga aaagttgcag aaccatacca gatacactgt
     2641 tcaaaccctc aattccagct tcatggcatt gctgaatgat gccgtgaaaa atggtaatct
     2701 gctctcaaat cgcttgaaag gtgttttcat cggccagagt gatatccctg ctgcaaacaa
     2761 gaaagtgact ctcaaagagt tcaagacttg gatagcaaag gcagaagaga ttatgccaaa
     2821 acaattctac gctctgacct atctgacaat ttttggattg agaagaggag aagtctttgg
     2881 attgcgtcca atggacatca ctcagaacga cagcggacgg gctatactgc atcttagaga
     2941 cagtcgaagc aaccagacct taaaagggaa aggagggctt aaaacgaagg attcagagcg
     3001 atatgtctgc cttgatgata tcggaacaga cctgatctat tatctgatag ctgaagcttc
     3061 taagattaag cgaaagttag gaattatcaa ggaacagcac aaggattata taactatcaa
     3121 cgagaaaggt ggtctcatca atccaaatca gctaaataga aacttcaatc tagtgaatga
     3181 agcaacagga ttgcatgtaa cacctcacat gatgcgccac ttcttcacga ctcaaagcat
     3241 tattgcaggg gttccgcttg aacaattaag ccaggcgctg gggcatacaa aggtttatat
     3301 gacggatcgt tacaatcaag tagaggacga acttgctgaa gcgacaacag acctatttct
     3361 tagtcatatt cgctaaaaaa gtccccgcca attccccgac caaaatccga aaaataccga
     3421 aaaatatcga aaaattattt ttagaatagt ccccaaaagc ctgaaataga gctaaaaaac
     3481 tccacctgat tcggtggagt taagggagat tattatgaaa aagaaaagtt taggatattt
     3541 gttacaacaa gttaggaggt cttcttgtaa ccgtttatag tatacccgac ctatcttaaa
     3601 caaatcttaa aaatctctta ggaccaaaca ctttctaaaa tatttgtttg ttcacgacca
     3661 ggacctactg agaaagtaga aatacgaacg ccaaccaatt cactcacacg acgaacatag
     3721 ttacgcgcat tctcaggaag atcttccaaa ttgcgaactc cggtaatatc ttctgaccaa
     3781 cctggcaact cttcatagat aggcttgcaa cgtttcaatt gctcaagact agctggatag
     3841 tagtcaatac gttgaccgtc aagatcatag gccacacaga ttttcacagt atccaaaccg
     3901 ctcaaaacat caatagagtt caaagaaagg ttagtaatac cagaaacacg acggctatga
     3961 cgcatcacaa ctgagtcaaa ccaacctaca cgacgtggac gaccagttgt tgtaccatac
     4021 tcatgaccca cttcacggat acgttctccc acttcatcaa acaactcagt tgggaaagga
     4081 ccatctccta cacgactcgt ataagcttta catacaccta caaccttgtc aatcttgctt
     4141 ggaccgacac cagaaccaat tgtcacacca ccagctacag ggtttgatga cgtaacaaat
     4201 ggataagtac cttggtcgat atctagcata acaccttgtg caccttcaaa aagcacacgt
     4261 ttgccattat caagcgcatc attcaagata acagatgtat ctatcacgta tttcttgatt
     4321 tgttgaccat attcgtaata ttcttcaaaa atatcatcga aaacaatcgc tttactgtca
     4381 tacaattttt caaaaagacg attcttttca gcaaggttac gttctaaacg ctcgcggaaa
     4441 ctatctttat ctaaaagatc tgcaatacga attccaacac gagcagcctt gtccatataa
     4501 gctggaccaa ttcccttaat tgtcgtacca atcttattgt cgcccttagc ttcttcttgc
     4561 aagcgatcca actcgatatg ataaggcaaa ataacatgcg cacgatcaga aatacgcaag
     4621 ttatcagttg ttacaccttc ctcatgaaga tagctcaact cttttacaag agatttagga
     4681 tttacaacca taccattccc aatgacagat attttttcag ggaagaaaat cccagatggg
     4741 atcaagtgca acttaaattt cttaccgtca atcacaatcg tgtgaccagc attatcacca
     4801 ccttggtaac gtgcaatcac ttctgcattc gctgaaagga agtctgtaat cttcccttta
     4861 ccttcatcac cccattgggt acctacaaca acaactgaag tcataatctt gtctgagccc
     4921 tcaggctctt cctttctcac atacatggca ggactctcac ctgcaattat atcttacaat
     4981 ttattataat aaaaaatcgc ctttttatca agaagaaaca atagaaagat ttgctatttc
     5041 caactattaa aaaatgattt agaaaaatta ctagctattt actatcatct ttccataaaa
     5101 gagtaaatta gttcggaaat ttactaaaat tacctcaaca agaaataaaa ccccgattca
     5161 ttaccaattt ttcaagatac aaacgataag caacacgata atggtaaaca ataaaatcct
     5221 tacgacaacc aatgccatat cttactaaat aataaattaa aaatttaaaa tgaacatgtt
     5281 cccagtcaaa attatcacca aatgtaggac catactcttc ttcaatacta tcatagaaat
     5341 tagccatctg ctcataaatt ttttgtaaca taatcaaata ctccttttct tttttataaa
     5401 cttattctaa caaaaaattt tacacattca ctatcaattc ctgaattgtt aaaataccag
     5461 cctcaacaag ataaaaatag gaaaagttga caaaatagaa acaaatttgc tacctaaatt
     5521 tcaaacaatt aaagttctaa aaagaccgcc ttaaaacttt tgggtaaatc ctattaaaac
     5581 tataatattt ttatataggt attatggttc tgattttcta gtataaaaaa attca
//
LOCUS       DAVLMQ010000086         5290 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000086 DAVLMQ010000000
VERSION     DAVLMQ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5290
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.087"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..212)
                     /locus_tag="VXF95_002040"
     CDS             complement(<1..212)
                     /locus_tag="VXF95_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1082522.1"
                     /translation="MKINKKYLAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIV"
     gene            complement(370..2820)
                     /gene="phtA"
                     /locus_tag="VXF95_002041"
     CDS             complement(370..2820)
                     /gene="phtA"
                     /locus_tag="VXF95_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HEV1082523.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAAEAFLSGRGNLSNSRTYRRQNSDNTSRTNWVPSVSNPGTTNTNTSNNSN
                     TNSQASQSNDIDSLLKQLYKLPLSQRHVESDGLVFDPAQITSRTARGVAVPHGDHYHF
                     IPYSQMSELEERIARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSN
                     SSLVSQLVRKVGEGYVFEEKGISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKE
                     NVAPRDQEFYDKAYNLLTEAHKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDL
                     LAFLAPITHPERLGKPNSQIEYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYV
                     TPHMGHSHWIGKDSLSDKEKVAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVK
                     GEKRIPLVRLPYMVEHTVEVKNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLF
                     ATIKYYVEHPDERPHSNDGWGNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVP
                     QVETEKVEAQLKEAEVLLAKVTDSSLKANATETLAGLRNNLTLQIMDNNSIMAEAEKL
                     LALLKGSNPSSVSKEKIN"
     gene            complement(3074..4807)
                     /gene="ptsP"
                     /locus_tag="VXF95_002042"
     CDS             complement(3074..4807)
                     /gene="ptsP"
                     /locus_tag="VXF95_002042"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HEV1082524.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            complement(4813..5076)
                     /locus_tag="VXF95_002043"
     CDS             complement(4813..5076)
                     /locus_tag="VXF95_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HEV1082525.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
BASE COUNT         1392 a         1116 c          983 g         1799 t
ORIGIN      
        1 acaatttgtt cggcgttgat cccctccctc ttactgactt catctggtgt caagttttct
       61 gccttttgac cagcctgatc accatctata taagcaactc gattagactc tttcttatcc
      121 tgaccagctt ggtaacgtcc aagctcatag gaacaaacac ttagggcaag gactgccact
      181 gaacctgcta gatatttttt attgattttc attctttcct cttttcttaa gtatatttga
      241 ttcactataa agtaataaac cggttaatta actagttaat agtttactct ttttaatatt
      301 gcttgtcaag aattttacat atatacataa taaaaatgaa agcctcttta tcgagacttt
      361 catttttcat tagtttattt tttccttact tacagatgaa ggattacttc cttttaacaa
      421 cgcaagtaat ttttctgctt ctgccatgat actattgtta tccataattt gaagagtcaa
      481 attatttcgt aaaccagcta gagtttctgt tgcattggct ttcagactag aatccgttac
      541 tttcgcaagc aaaacttctg cttctttgag ttgggcttct actttttcag tctctacttg
      601 agggacttct ggctcagcag gtgtttcctc tactggctct tcatccgctt tgaagttctt
      661 atttggatct tcactgtggt ctttcttgcc taacacatgc tcactggcat tgccccatcc
      721 atcattagaa tgtggacgtt cgtcagggtg ttctacgtag tacttaatcg tcgcaaacaa
      781 atcttccaag gtatagccat ttggagcttt gtatgtgtga tcatcaaacc aagcaaattt
      841 aatattatgg taatgatcct tatgaggaat aatcaaatta ccgtttttaa cctcaactgt
      901 atgctcaacc atatatggaa gtcgaacgag tggaattcgt ttttcccctt tcacacgatt
      961 gtaaatagct gctgcactat ctccagttgg atttgcttta acatctgcgt ctggagatgg
     1021 aggtaggata cctttttctt tagtataggc ttgagctgca actttttcct tatcagaaag
     1081 gctatctttt ccaatccagt gactatggcc catatgaggc gttacatatg catctccttc
     1141 atcactgatt atatcatgtt catcaaaaat gtaaccatct gacgttgtat acttatcagc
     1201 taattgagca atacgaactt cgtcttcagt atactcaatt tgagaatttg gcttgccaag
     1261 tcgctctgga tgggtaattg gtgctaggaa tgccaataaa tcatctacca atttttcttt
     1321 attagtcgat tcatcattca agcgttctaa taatttgtct aaggcttgga aatcagaatt
     1381 acgaccctta ttttcaaaca aggctttatg agcctcagtt aacagattat atgctttatc
     1441 ataaaattct tggtcacgag gagcaacatt ttctttttta gcagttaaag tgtgtgaaac
     1501 actctcttgt tttgataact tactttcaag atttttaaca gtttcagatg gtaaatcttt
     1561 cgcaaagaca taacgagaga tgcccttttc ttcgaataca tatccttccc caacttttcg
     1621 taccagctga ctaaccaaag aagaatttga gtctatttta agatttggtg caggttgcgg
     1681 gcctggacta ggttccggag tcggttgtgg acttggttgt tctggccttg aatctggtac
     1741 ccaatggttt gaacgataac gaaggggaat aatacgagcg attcgttctt ccaattcaga
     1801 catttgagag taagggatga agtggtaatg atctccgtgt ggcactgcaa cacctctagc
     1861 tgttcgactt gtgatttgcg ctgggtcgaa aacaaggcca tcagattcta catgtcgttg
     1921 actcaaaggc agtttgtaga gctgtttcaa gagactatca atgtcattac tttgacttgc
     1981 ttgactgtta gtgttgctgt tgttgcttgt gttagtattt gtagttcctg gattgcttac
     2041 agaaggtacc cagtttgttc ttgaagtgtt atcgctattt tgtcggcgat aggttcttga
     2101 atttgacaga tttccccgac cagataggaa ggcttctgca gcagccaact cgctagctga
     2161 taactcattc ttaggaatgt aatggtaatg atctccatga ggaacgatat aagcatcacc
     2221 agtatcctct atgatatcag aagcattaaa gatataacca tcatctgtag tatagcgtcc
     2281 ttgcgaacgt gccaaggcaa cagcaccatc gtttcttgga gtcccacctt cacgatgttg
     2341 actatgctct tgtttttgtc gattgatttc ctcttttgta cggacgttat ccgcgtgggc
     2401 agcatcctta aggtaaacat agtattttcc atctaccttg ataacatatc cacccttgac
     2461 ctcattaaca atatcctcat cttttagctt atagtttgga tctttcatga gtaattcttc
     2521 actgaaaatc gcatcataag gaaccttacc attgtaataa tgatagtggt cgccatgtga
     2581 agtgacatag ccttggtctg ttatcttgat gacgatttgt tcggcattga ttccttcacg
     2641 cttgctaacc tcatcaggag tcaaattctc cgttttttgc gtcgcttgtt ttccatctat
     2701 ataggaaaca cgattatttt ccttaaccgt tctagcttga tacagtccca actcgtaaga
     2761 acaaacactt aaaatcaaag ctgccgcaga accaacaagg tatttcttat taattttcat
     2821 cgaaactctc tttctatttg atatttctag ttgcaattca tttctaaatt gcagaaactc
     2881 ctctctatta cttaactggt taatagttta ctcctaaatc tccaacttgt caagaatttt
     2941 atgaaccatt taagtatttt ttgttctgac cactactttt tcaaggttgg actttctata
     3001 agaaagattt tcttgaaaat tctttttaaa atatcaaaaa aatccctgta actgagttgc
     3061 agggactttt cgattaatca aaattaacgt attctttttg aagttcaaga acttcttcca
     3121 ttgttgagca ttctgtaagg gcacggtttg cgtactcttc catcttagct gtgtcgagtt
     3181 tcttcatcaa gctgcgtgta cgaagtacag atgttgctga catagagaac tcatccaagc
     3241 ccattccgac aagaagtgga acagcttgtt ggtcaccagc catctcacca cacataccag
     3301 cccatttacc ttcagcgtga gctgctttga tcacattgtt aatcaagcgt aggattgatg
     3361 ggttgtatgg ttggtaaagg tatgaaactt gttcgttcat acggtctgct gccattgtat
     3421 attggatcaa gtcgtttgta ccaattgaga agaagtcaac ttctttagca aattggtctg
     3481 caagcatagc cgctgcagga atctcgatca tgataccaac ttggatgtta tccgcaactg
     3541 caacaccttc agcaagaagg tttgcttttt cttcatcaaa gactgctttc gctgcacgga
     3601 attctttcaa gagcgcaacc attgggaaca tgatacgcaa ttgaccgtga acagacgcac
     3661 gaagaagagc acggatttgt gtgcggaaca tagcatctcc agtctcagag atagagatac
     3721 gaagagcacg gaatccaagg aatgggttca tttcgtgagg catatcgaag taaggaagtt
     3781 ccttatctcc accgatatcc attgtacgaa cgacaacagg tttaccgttc attccttcaa
     3841 gaacagcctt gtatgcttca tactgctcat cttcagttgg gaagtcttga gaatccatgt
     3901 acaagaactc tgtacggtaa agtccaacag cttctgcacc gttgttgtta acaccttcaa
     3961 cgtcttttgg agtaccaata ttggcagcca actcgaagtg tttaccgtca gcagtcactg
     4021 tttgagcatc tttcaaaagt gcccattcag ctttttgttt cgcataggct tcaccagctg
     4081 ctttaaattc tgccgcttgt tcatctgttg ggttgataat cacttctcca gtgatcccgt
     4141 taacagcaag gatgtcaccg tctttaacga tttcagtgat gttgtttgta cctaatacag
     4201 cagcaatttc aagtgtacgt gccatgatag ctgagtggct tgtacgtcca ccaatgttgg
     4261 ttacaaaagc ttttacaaag tttttgtcca attgagctgt atctgaagga gtcaagtcat
     4321 gcgcaatcac aatcacttct tcattgatag aagctgggtt tggcaatttt ttaccaagaa
     4381 ggtttgccaa tacacgtttt gtcacgtcgc ggatatccgc tgcgcgttct tgcatgtatg
     4441 ggttgtcttc catgccttca aagatagtga taaacatatc tgtaacttct ttcagacctg
     4501 cttctgcatt cactttcttc gcacggatag tttccttgat ttggctgatc atttctgggt
     4561 cagcaagaac cattaagtga gcatcaaaaa cttgagctgc ttcttcaccg agcgtaccta
     4621 ctgctttctc gcgaataaca gaaagctcgt cttgtgatgc ctgtagagcg gcatcaaggc
     4681 gagcttcttc tgcgtttgta tcttcgactg taatagtctc aaatgacaaa tccggctgaa
     4741 cgagtagata tgcttttgca actgcaacac cgtcagatgc tgcgattcct ttaagcattt
     4801 ctgtcatttc ccttatgcca atccttcttt ttccattgtt tctgagattg cagcgatagc
     4861 gtcatctgca tctgcacctt cagctgagat agttacgtca gcaccttggc caacaccaag
     4921 actcataaca cccataattg atttaaggtt aactgattta cctttgtact caagagtgat
     4981 atctgaagca aatttgctag cagtttgtac caacaatgtt gctggacgtg cgtgaatacc
     5041 tgtttctgcc actacgtgga aatctttaga agccatagtt tgactctcct tttgttcttt
     5101 ctttttttga gttatatgtg ataaccctta caatttagta ttataccatc ttctaggatt
     5161 tttttcaagc attttctgga ttttccttca atttcctttc agataacttg ctgaaaatct
     5221 tctatcctag ataacaaaac acaggatata gtttctttaa aaacaattta taggataatc
     5281 attgctattt
//
LOCUS       DAVLMQ010000087         5265 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000087 DAVLMQ010000000
VERSION     DAVLMQ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.088"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..482
                     /locus_tag="VXF95_002044"
     CDS             <1..482
                     /locus_tag="VXF95_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082526.1"
                     /translation="LYGSSLISFLWMYGQRKQAHKVNMKSRMKWLGIGFVSLLIISLC
                     FSLIHAQESTNQANLIGLQHQVPWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVA
                     LTSVLFALAHHPGTIIAWCLYVSLGMFLGLVRYKLDLWGSMGLHLVWSLLVYSLLLF"
     gene            684..821
                     /locus_tag="VXF95_002045"
     CDS             684..821
                     /locus_tag="VXF95_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004264816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SapB/AmfS family lantipeptide"
                     /protein_id="HEV1082527.1"
                     /translation="MAEEVLNLQLVSVQVDETDEVDGMRFSTFSTNRCGNWSAFSWEN
                     C"
     gene            1111..2514
                     /locus_tag="VXF95_002046"
     CDS             1111..2514
                     /locus_tag="VXF95_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase"
                     /protein_id="HEV1082528.1"
                     /translation="MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICH
                     EMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGP
                     YILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVP
                     PDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLG
                     FDGTYSSERLASECKALKILNEWSEMPKIYWYGKIWEHTFLGIEHMKGVPLNRWVTNN
                     FPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIID
                     WEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNY
                     VSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIE
                     SEQDIQDFIIKAFLLVN"
     gene            2703..3323
                     /locus_tag="VXF95_002047"
     CDS             2703..3323
                     /locus_tag="VXF95_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1082529.1"
                     /translation="MKDVVYSITPENKLSIDFSFKSPFRVLLTGTSGSGKTTILNLIN
                     GSLKPQKGYVNLLSHGKKSSDSIPTVDQTPYIFDTTIRENVTLFQNEYFSDDQIIEVL
                     KKVNLYEELEKIDILNYKCGENGSNLSGGQKQKIALARALIRNNKVYLFDEISANLDN
                     DNSNSIHDILFNLGISFIEVSHHYDLNDKRYTDIYKLENGTLFKIK"
     gene            3338..4078
                     /locus_tag="VXF95_002048"
     CDS             3338..4078
                     /locus_tag="VXF95_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082530.1"
                     /translation="MDKDYILKVKGLYHQFLLGNNKTLQVLKNVSLSASRGEFISILG
                     ISGSGKSTLLKCISSLLEPTSGEVILNGINPYKIRNAKLSSIRRNEVSFIFQAYNLIP
                     SLPVIENIALPLRLSQKKLTIKNVENLLKRMKFNAGLNDFVGTLSGGEQQKVAIARAV
                     IADSDIIFADEPTGALDSVSREVIFELLRELVGAGKCVIMVTHDIELASKTDRALILK
                     DGKIFKELHRPSGEELYKILEVQSTTEE"
     gene            4081..>5265
                     /locus_tag="VXF95_002049"
     CDS             4081..>5265
                     /locus_tag="VXF95_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000945307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HEV1082531.1"
                     /translation="MLRLVYYQFLHNKKQWLGVSPVIFVSSLVMGLAVNGVINVENNS
                     QVFVGLPDPKPIFMFPIVFGGVTLFFVLSNIINMLVEIFRDDYELLEVLGASRLQLSF
                     LVGGQIFIISSIISFIAYLCSIFVTSNYYYFLQYFFGENILPDIQFQTSAVGCIITVV
                     LISFLAFLSGCFYTFKKIRNRKSSKIRHVLSIVKRILLLAGFSVIWLLSLQQIFQDST
                     ILAKAQIIFNIVILDIVIIYQLSPFIQSCFIKLLSIIIFRNNFMFIVSKWNLLYCKSY
                     IKSISAAITGAILLISSFQMISQNILSQFQDDSDLELKVAFIVYVGAPILIVLANIIS
                     IAFLSSHQERIEIQQFEILGTSNYQMVKIKVGEAIFLTFVTSLIAFLLNIKIMALIYY
                     SLE"
BASE COUNT         1791 a          673 c         1011 g         1790 t
ORIGIN      
        1 ttctctatgg ttcgtcactc atttcttttt tatggatgta tggccaacgc aaacaagctc
       61 ataaggtaaa tatgaaatct aggatgaaat ggcttggtat tggattcgtt agcctactga
      121 ttataagtct atgttttagc ctaatccatg cgcaagaaag cacgaatcaa gcaaacttaa
      181 ttggacttca acatcaagtt ccttggtttt catttttatt gtttttaatc aatgcgagta
      241 tggttgaaga atttctgtat agagaaattt tatggaactt ggttagaaaa ttagatattc
      301 gagttgcttt gacaagtgtt ttatttgcct tagcacatca tccaggaacc attatagctt
      361 ggtgtttgta tgtatcgctg gggatgtttt tagggcttgt acgctacaaa ttggacttat
      421 ggggcagtat ggggctacat ttggtgtgga gcctactagt ttatagtttg ctgctttttt
      481 aaaataggta acctgatttt taggtaactt ctaaaactaa cttccagttt tgggagagag
      541 atggaagtta ctttgaaaag ttacggaaac attattttct acgtgacaac attgtatcat
      601 tgcttgcatt ttactgctgg agagagtata atgaaggtgg ataaagcact taatcccaaa
      661 aatttaaata ggaggagtta gctatggcag aagaagtatt aaatcttcaa ttagtatctg
      721 ttcaagttga cgaaacagat gaagttgatg gaatgcgatt tagtacattc agtacaaacc
      781 gttgcggtaa ctggagtgct tttagttggg aaaattgtta attcatttaa attgtaaact
      841 ttagggattc tctggagtta tggatctcgt tccaatatgt gcacgttgga atgtcagtgc
      901 ttatatgggg ggaatccaaa ggattctccc tttttatttt aataagtctg tctagctata
      961 gatatattaa gtttgataga atttcttgga gattttgtta tggattataa tttcaatttg
     1021 gagcatcctt tctttttcac taataatgat tatagtacag atactagcat aaagtactaa
     1081 gtaagtctgc cttttaattg gcacgaagta atgaataatg atgagtgggt ttatcaatac
     1141 cctattggaa aatttgttga aagacaaggg tggaaaatac acattagttc agagtataat
     1201 agttcacacg aattgttaca agatgtagca aaaatttgcc atgaaatgcg aattccattt
     1261 aaacatctta gtacagaaga caaatttatc atgcgaaacg ggaaattggt tagtcgagga
     1321 ttttctggta aatttattac atgttatcca aatcaaaatg aattagagtc ggttttgcaa
     1381 aggttagaaa gtgccttaaa gcaatataat gggccatata ttttaagcga taaacgttgg
     1441 gatgaagcac caatatatct gaggtatggt gtgtttaggc cgtcaaggga tgatgaaaag
     1501 aaggttgtta ttgatgaatt aattgttggc gatgaagttg ttaaagatga acgtttacca
     1561 gtatttaaaa ttccaaaagg tatagtgccc cctgactttt tgaataaatg gcttgacaag
     1621 aaagataaaa aacagggaga ctttcccttt attatagata atgcaattag attttcaaac
     1681 agtggtggga tatataatgc tagactaaaa gaagatggga aaaaaataat tttaaaagag
     1741 gctagaccgt atacaggtct aggatttgat ggtacttatt cttcagagag attagcttcg
     1801 gagtgcaaag cactaaaaat tctaaatgaa tggagtgaga tgcctaaaat atactggtac
     1861 ggtaagatct gggagcacac cttcttagga attgaacata tgaagggcgt tccactaaat
     1921 agatgggtta ccaataattt tcctttatat gaagttgttg ataagaccaa agattatcta
     1981 ttgagagttt caaagatagt agaaaaactc atcgatttaa cgaataagtt tcattctgaa
     2041 aatgtatatc atcaagattt acatttagga aatatcttgg ttaaggatga agatgagatt
     2101 agtataatag actgggaaca ggctgtcttt tcgaatgatg aaaaagttgt acataaagtt
     2161 gcagcccctg gttttagagc atggcgagaa acacttccca gtgagataga ttggtatggt
     2221 attagacaaa tagctcatta tttatacatg ccactagtaa ctacatcgga tttgacatac
     2281 aactatgtaa gtcaaaccag gatagaagga aaaaaactat ttgagtcttt gggttataca
     2341 agagaacata tagattatgt agaaagttta ttgtcatatc tagattctaa atgtccacag
     2401 attgagaata tttccaggaa aaaagtttta aaacccatgc atgagattag aactatcgag
     2461 agtgagcaag atatacaaga ttttattata aaagcttttc ttttagtgaa ctgataggta
     2521 ttttcttagc aaacgataaa gttttagggc cgatacaatc aattgcctat tcattaaata
     2581 agataaatac aaccaaagat ttaaggaaac cgtttttaaa atacttaagt ggagagaaga
     2641 attttgtaga cgctgaacat gataataacg gactgtatac ttcatcaata gatgagatac
     2701 acatgaaaga tgttgtatat tctattacac cagaaaataa attaagtatt gacttctcat
     2761 ttaagtcacc atttagggta ttattaacag gaacttctgg cagtgggaaa acaacgattt
     2821 taaatttaat taatggttct ttaaagccac aaaaaggtta tgtaaatttg ttatcacatg
     2881 ggaaaaagag ttcagattca ataccaacag ttgatcagac accatatatt tttgacacta
     2941 ctattcgtga gaacgtaact ttatttcaaa atgaatattt ttcagatgat cagataattg
     3001 aggtgttaaa aaaggtaaat ctatatgaag aattagaaaa gatagatata ctaaattata
     3061 aatgtggtga aaatggtagt aatttgtctg gaggtcaaaa acaaaaaata gctttagcta
     3121 gagctctgat tagaaataat aaagtgtact tatttgacga aatatcagct aatttagata
     3181 atgataattc aaattccata catgatattc tgttcaattt aggtatttca tttattgaag
     3241 tttcacatca ttatgactta aatgacaaga gatacactga tatatataaa ttggaaaatg
     3301 gaacactttt caaaattaag tgattggagg caagaatatg gataaagatt atatattaaa
     3361 agtgaaaggg ctgtatcatc aatttttact aggaaataat aaaacgttgc aagtgctgaa
     3421 aaatgtttct ctttctgctt cgagaggaga atttataagt attctaggaa ttagtggttc
     3481 tggaaagtca actttattaa aatgtatttc tagtttgctt gaaccaacaa gtggggaagt
     3541 aattttaaat ggaatcaacc cctataaaat cagaaatgca aaattgtcaa gtataagacg
     3601 taacgaagta tcttttatat ttcaagcata caatttaata ccttccctgc cggtaataga
     3661 aaatatagca cttcctttgc gattatcaca aaaaaaatta actattaaaa atgtagaaaa
     3721 cttactcaaa agaatgaagt ttaatgctgg cttaaacgat tttgttggaa ctctgtctgg
     3781 tggagaacaa cagaaggttg ctatagctag agcggttatt gctgatagtg atataatatt
     3841 tgctgatgag ccaactgggg ctttagacag cgtttctcgt gaagtaattt ttgaattatt
     3901 gagagagtta gtaggggcgg gtaagtgtgt aattatggta acgcacgata tagaattggc
     3961 ctcgaaaact gatcgtgcat taatattgaa agatggaaaa attttcaaag aacttcatag
     4021 acctagcggg gaagagttgt ataaaatctt agaggtacaa tcaactacgg aggaatagag
     4081 atgctcagat tagtttacta tcaattttta cataataaga aacaatggtt aggcgtttca
     4141 ccagtaattt ttgtttcgag tttagttatg ggattggctg ttaatggggt aattaatgtt
     4201 gagaataatt cgcaagtatt tgtcggactt ccagatccta aaccaatttt tatgtttccg
     4261 atagtattcg gaggagtaac attattcttt gtgctctcta acataataaa tatgttggtt
     4321 gaaattttta gagatgatta cgaacttctg gaggtgttgg gagcaagtcg ccttcaacta
     4381 tcatttcttg tggggggaca gatttttatc atttcctcga ttattagttt tattgcatat
     4441 ctatgctcta tatttgttac gtcaaattat tattattttt tacaatactt tttcggggaa
     4501 aatatattac ctgatatcca atttcaaacg agtgctgttg gatgtatcat tacagtagtg
     4561 ttgatttcat ttttagcctt tctaagtggt tgcttttata cgttcaagaa gattagaaat
     4621 aggaagagtt ctaaaataag gcatgttctt tcaatagtaa aaagaatact gctattggct
     4681 ggttttagtg ttatctggtt gctttctttg caacaaattt tccaagatag cacaatttta
     4741 gcgaaggccc agataatatt caatattgta atcttagata ttgtgattat ttatcaatta
     4801 tctcctttta tacagtcatg ttttatcaaa ctactttcta taattatatt tagaaataat
     4861 tttatgttca ttgtttcgaa gtggaattta ctatattgta agtcttatat aaaatctatc
     4921 agtgctgcaa ttacaggagc tatattacta atttctagtt ttcaaatgat ttctcagaat
     4981 atactatctc aatttcaaga tgacagtgat ttagagctaa aagtagcatt tattgtctat
     5041 gtaggagcac caattttgat agtacttgca aatattattt caattgcatt tttgtcatcg
     5101 catcaagaaa ggattgagat tcagcaattt gaaattttag gaacttctaa ttaccagatg
     5161 gttaagatta aagttggtga ggctatattt ttgacatttg ttacttcatt aattgcattt
     5221 ttacttaaca ttaaaattat ggctttaata tactactctt tagag
//
LOCUS       DAVLMQ010000088         5235 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000088 DAVLMQ010000000
VERSION     DAVLMQ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5235
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.089"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(381..1109)
                     /locus_tag="VXF95_002050"
     CDS             complement(381..1109)
                     /locus_tag="VXF95_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HEV1082532.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            1267..2676
                     /locus_tag="VXF95_002051"
     CDS             1267..2676
                     /locus_tag="VXF95_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1082533.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQIIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTDDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIGENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            2694..3989
                     /locus_tag="VXF95_002052"
     CDS             2694..3989
                     /locus_tag="VXF95_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HEV1082534.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTRFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            3994..4302
                     /locus_tag="VXF95_002053"
     CDS             3994..4302
                     /locus_tag="VXF95_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1082535.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNIPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            4299..4607
                     /locus_tag="VXF95_002054"
     CDS             4299..4607
                     /locus_tag="VXF95_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HEV1082536.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
BASE COUNT         1764 a          878 c          958 g         1635 t
ORIGIN      
        1 agaagatatg aacaaataaa ttgggagatt gaaattcatt tctagcaatt tgttagaagt
       61 cacagtctac tattctaacc tcagtatact atatgtgtta caagaaaaga ctcaaaaact
      121 tctcgtcagt gtaagaatgt ttgaaacact atttaaaact aaataactat aagaagtaga
      181 tcaggtgaac aatttcagta cctactctat aagctatacg aagatatttt tcaacatgat
      241 ggataaaacg atcactcttt taaagccatc ttatttagaa aagagaaacc atttaagcat
      301 agatgggacc ttcttgccct gttttaaatt tttcttaaac tagagtctgt aaaagattgg
      361 cttcattttc acattttctc ctaggaggaa tgtcgtaatg caaaagaatt aaattcaaat
      421 aaatcatagc gatgacgact aatcgagtac tcaaacggag ttccgttatc caaataagcc
      481 acttgttcta cttcaaatac cggttccgtt ggaaggagct gcaagtaatg ttgctcattt
      541 tctgaactag aagaagctcg caagattttt gtagcactgg caatatgcaa tcctaacttt
      601 ccttcaatgt aattgtaaat cgatttttgt aaaatatctt cagtaatacc tggaataaca
      661 tcggtactca tataagtttg ttccagaaca taaggtttac cgtcaataat acgcaggcgg
      721 taaatattat aaactggact ctgcaaagcg acctgtagtt tttctgctaa aaattcattt
      781 gcaaattcta atttgaagtg aataatcctc gagtcaattg tagaatgagc atcttcagat
      841 atttttgtca gtccccggat atctctttct ggaacgatta attttctttt tgagctgcca
      901 cgagagagaa caaaggttcc ctgcccacgt tttctaaaaa ttaagccctc agaaactaac
      961 aagtctaaag cttttttgat cgtcattcga ctacaggcaa actgtttagc taatgtcatt
     1021 tcatcaggca attgttcgtt catggtatat ttattacaaa gaatcttttc acgaatctca
     1081 ttgtaaataa ataaatattt tgtactcatt taatctggtt ctctctataa tattctaata
     1141 gtagtataac aaagttcaag aaatgaggca aacacaagat atgtataaac aatttttaaa
     1201 aatgtctaga caaattttaa aattatgcta tactttatgt atagaataat agaaaggagg
     1261 ttgagcatga aaaaaaagtt agtatttcct aatctgtttt ggtggggggc tgcttctagc
     1321 ggacctcaga cagaaggtca atatggaaaa gtacatgaaa atgtgatgga ctactggttc
     1381 aaaacgcatc cagaagattt tttcgataat gtcggacctc ttgtagccag taactttttt
     1441 catacttaca ccgaagattt ccacttgatg aaggaaattg gagttaattc tttccgcact
     1501 tccatccaat ggagtcgact catcaagaat ttagagacag gtgagcctga tccaaaaggt
     1561 attgctttct acaatgccat cattgaagaa gctaaaaaga accagatgga tcttgtgatg
     1621 aatttacatc attttgattt accagtggaa cttcttcaaa aatacggtgg ttgggaaagc
     1681 aaacatgtag tggagttatt cgtgaagttt gccaagactg ctttcacatg ctttggagat
     1741 aaggttcatt actggacaac tttcaatgag ccaatggtca ttccagaagc aggatactta
     1801 tatgctttcc attatccaaa tctaaaagga aagggaaaag aggccgtaca aatcatctat
     1861 aatctaaacc ttgctagtgc aaaagtgatt caactatatc gctcattagg acttgatgga
     1921 aagattggga ttattttaaa cttgacacct gcttatccaa gaagtaattc tccagaagac
     1981 ttagaagcaa gtcgatttac agatgacttc tttaacaaag tcttcttgaa tccagctgtt
     2041 aaaggaactt tcccagaaag attggtaaaa cagctagaga gagatggcgt gttatggagt
     2101 cataccgaaa aagagcttca actgatgaaa tcaaatacgg ttgattttct tggagtaaac
     2161 tactaccatc caaaacgtgt tcaagcacaa gcaaatcctg aggaatatca gacgccctgg
     2221 atgccagacc aatacttcaa agagtatgaa tggccggagc gtcgcatgaa tccatatcgt
     2281 ggttgggaaa tttttccgaa agccatttat gatattgcta tgattgtgaa ggaagaatat
     2341 gataatattc catggtttat cagtgaaaac ggaatgggtg ttgaaaacga agcacggttt
     2401 atcggtgaaa atggagttat cgatgacgtg tatcgtattg aattttatga agaacattta
     2461 agatggctac ataaagccat tgaagaggga agtcactgtt ttggatacca cgcttggacc
     2521 gcatttgatt gctggtcttg gaataatgca tataagaatc gttacggatt tatctccgtt
     2581 gatttagaaa cgcaaaagag aaccatcaag agctcaggaa gatggtatcg caaagtaagt
     2641 gacaataacg gttttgaagt agaaattgag gagtaaagag aggagatatt cagatgaaaa
     2701 actcaaaatt tatagatcaa tttgccacct ttgctggtaa actagggaac caaattcatt
     2761 taaaaaccct aagagatgca ttcgtaacag taatgccatt atatattttg gcaggtttaa
     2821 tcgttctttt gaacaacacg gtatttaagt ggattttcca aggggataca ttaacaagat
     2881 tccaatattg gggaataaca attgcaaacg gtactttaag tatttcaggt atgattattg
     2941 ctgtaatggt tggttatttc ttagctaaaa acagagattt cgaaaacccg ttagcagcat
     3001 caatgctatc attagtttct ttaattgtga tgatgccaaa tacagtttct gtagttcctg
     3061 acggagcaaa agatgcggta aacatttcag gtgttctttc attcaacaac acaggtacag
     3121 gcgcaatgtt cgccggggtt atcgtagcga ttattgcaac agaattattc attgaattat
     3181 caaacgttaa agctttacaa atgaaccttg gtgaaaatat tccaccagct gttagtagat
     3241 catttagcgt attacttcca gtcatgaccg tcatctcctt atttggggtt gtttcagcat
     3301 tattattcaa tataactgga atgaacttaa tctcaatcat tacaatcttt attcaagaac
     3361 caattcgtca tattggtaca agcttaatcg gggtcattat tatttactct ttaggaaata
     3421 tgttatggct atttggtatt caccaagcag ttatttacag tgccatccta gaaccattac
     3481 tattaattaa cattactgaa aacatcactg cagcaaataa tggacaagcc attccacaca
     3541 tcatcaacct atcacaaata caaacattcg ctttaatggg tggtagtgga tctacattat
     3601 gtttattaat agcaacattc ttagtgagtc gcaatgctgt ctctaaaaac gtggctaaat
     3661 tatcttttgg acctggtatc ttcaatatca atgaaccagt attattcggt tacccaatcg
     3721 tttataacat ttcattagct attccattta tcacagttcc agtccttggt attttaatca
     3781 gctacttagc aacagttaca ggattcatga gtcctgcatt tatacaagtt ccttggacta
     3841 caccagtatt cttaaatgca tggttagcaa cagcagggga cgtgagagca gttctagttc
     3901 aattcatcat ctttgcactt ggagttcttc tatacattcc atttatcaaa gttaatgaca
     3961 aagttgttga gcaagaaatg gaaggttaag attatgaaac aaattttatt agtatgtaat
     4021 gcgggaatgt cgacaagtat gcttgttaaa aaaatgcaac aaagtgcgac tgaacgtggg
     4081 attgaaattt ctatccaagc aaaatcaatg acagaagcta aaaagaatat ccatgaagca
     4141 gatgtcattc taattgggcc acaaattcgt tatgagttac ttgctgtgaa agaaattgca
     4201 ggaaatatcc ctgtagatac cattgatatg cgggattacg gaatgatgaa tggagcaaaa
     4261 gttctggaac aagcacttgc atggatagga gaaataagat gacagaagaa atggaatata
     4321 tctgttttca gctcattgcc aatagtggag cagccaaatc atcctttatt gaagccatcc
     4381 aactagctaa ggcaggaaat ttaaaagaag cgaaaattaa agttgaagaa gcggaagact
     4441 ccttagtaga agcgcacaag attcactcta atctcataca aaaagaagct actggagaaa
     4501 aaataggatt ctccttgcta tttatgcatg cagaagacca aatggcttca acagagatta
     4561 ttcagttgct atctaaagaa ttcatcgatc tctatcaaaa taaataggaa cactgtcgtt
     4621 cccatctgtc tttattaatg acggctacat tgtaggaacc tccaaaagtt ggacaaaatg
     4681 attgaaagga ttggatcctg cattacacaa gatccaatcc ttttctttta ctctagtttt
     4741 tataatgtgt tgaatttaga atagtccact gcagtttcta aaaaattgct ggaaatagat
     4801 gttaagctcc aatttatttg tttatatctt atttcagttt actatactag cttattattc
     4861 tagtaaaaaa ttgaatgagc cactatttat ttaatatgta tgatgaggga atgactcaaa
     4921 aacttcttgt cgatataaga atatctgaga tagtatttta aaacgaaagg actataaaag
     4981 ctcatttcct tcgcacttat tttatagaga tctatcatta tactctttag aaatcaaaaa
     5041 gcaacacacc ttgtcatcgt tttatcgtaa atctgttaat gagggggcta gtcttatctg
     5101 caatctcaaa tcagtgtttt gagctgaatg gcactcgttt tctagtttgc tctttgattt
     5161 taattgggcc ttagtaaata ctactcttaa attaaactat agtgaattga aataagatgt
     5221 gaacaactct atcag
//
LOCUS       DAVLMQ010000089         5213 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000089 DAVLMQ010000000
VERSION     DAVLMQ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5213
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.090"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            84..917
                     /locus_tag="VXF95_002055"
     CDS             84..917
                     /locus_tag="VXF95_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase family
                     protein"
                     /protein_id="HEV1082537.1"
                     /translation="MNPLKECYEKNGILIAAHRGTNGGNILQNTSKAYLNSIRHNADM
                     FEVDVIRSKDGEFFAFHDGQEPLVFGEKIDIRTLSSEEIQRKECFNSLNEPILQKIEK
                     ISDVLKNFEGQSLINIDRSWFYWDTFLDKLKTYPSLNQVLLKSPVKKELLEMLRDSGL
                     NIMYMPIIKTIEELDFVLSFEGINIVAVELVFQDLENPIISKKVIDDLHEKGLLIWVN
                     ALTLSDSIILSAKIDDDTAIAHDGESWGKLVSIGFDIIQTDWPLLLYQYLVEKNKKIK
                     K"
     gene            944..2005
                     /locus_tag="VXF95_002056"
     CDS             944..2005
                     /locus_tag="VXF95_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082538.1"
                     /translation="MFKNFKKIAFTSSLILLAACSNNASNTNQSTDEGSVDKSQEIVI
                     YTNSASNGRADWLQTKASEQGYNLRLVDISGGELADRLIAEKNNAVADMVIGLNKLEF
                     NRIKAEKLLVKYSPKWADEVDSSLGDSEGYYSPIVNQPLVLIGNKDAKMPSDWTDFTD
                     SSYKGKYGISKLSTGTSKNIFASIVSRYKDEKGELGISDEGWKVAKAYLKNAHVYAEG
                     EDYISSIMDNNNELKYSMMWGSGVLQNQKEREYKFQVMSPKVGVPYVTEQVGILNTSK
                     KQALLKEFVDWFGSSELQKEWSDKFGSIPANKKALEQAKDELKQFANSVKPQELDWEF
                     IGKNIDSWIEKAQLEFVEQ"
     gene            2022..3026
                     /locus_tag="VXF95_002057"
     CDS             2022..3026
                     /locus_tag="VXF95_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082539.1"
                     /translation="MITFKDIQIKYNDFIAIDNLNLTINEGEFFTFLGPSGCGKSTTL
                     RALVGFLEPSQGQILVDNQDITNLDPEKREIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VSPEIIKAKVHEIAKKINISDEQLNRNISELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVSLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGFIEQVGTPY
                     DIYNQSETQFVCDFIGSINKISQEVLKKLQGENKYFKETEGYIRLERVKLEKTSPQDL
                     SITGVISDIEFNGVLIKYKVDLSNSESIHIIEKNDGLSRHIIEEKVTMYINPRDIMQF
                     "
     gene            3038..4732
                     /locus_tag="VXF95_002058"
     CDS             3038..4732
                     /locus_tag="VXF95_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1082540.1"
                     /translation="MRKSLNWKDWLIRLGVLWLIFALIIYPNIELLSGVFYKNGSFTL
                     EAFNKIIHSQRAMSSIFNSFILAISMVFTVNIVGTLIVLLTEYWDIRGSKILKLGYMS
                     SLVYGGIVLATGYKFVYGANGLVTKTLSSIIPGLAPNWFQGFGAVLFIMTFACTSNHI
                     MFLTNAVRSVDYHTIEAAKNMGASPLKVFFSVVFPTFKPTLFALTILTFLTGLSAVSA
                     PLIVGGKDFQTINPLIISFAKTTSSRDLAALLAIMLGLATILLLTLLNHVEKGGNYVS
                     VSKTKASIKKQIISSPLWNTLAHIVAYVLFAIYMLPIVLIILYSFTDSLTIKTGTLDL
                     SKFTLANYANLFTDAQSFRPYLVSVVYAILAAVIATIIAIVISRIVHKNKSKFDKFFE
                     YGALIPWILPGTLIALGLMFTYNIPHLILFNLVLVGTVIILLIAYTIQKLPFSYRMIR
                     AVFFSIDNDMEEAARSMGASSFYTMVRVIIPYILPVVLSVVVLNFNSLLSDYDLSVFL
                     YHPLFQPLGIVIKQSTDETATLNAQAMMFVYSVILMIMSSAALYLSSLFQGKRGKR"
     gene            4734..>5213
                     /locus_tag="VXF95_002059"
     CDS             4734..>5213
                     /locus_tag="VXF95_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HEV1082541.1"
                     /translation="MNLSYELSIWEILLRCFLAILFGGIVGYERGVKNQAAGIRTYLL
                     VCLGTCVVMMTNQFITSRYGSGDPSRMGAQVISGLGFLGAGTIMVTNQKVKGLTTAAG
                     LWSSATIGLAIGIGFYEGAILAGVVLIAVLTLFTPLKDYLNSKTKIADYYLVFSSLEG
                     "
BASE COUNT         1787 a          731 c          957 g         1738 t
ORIGIN      
        1 aatgaaacgt tccaacttat ctattgatac gttccaagaa atcggataca atgtaattaa
       61 caataaagat aggagaaaat aatttgaatc cattaaaaga atgctatgaa aaaaacggta
      121 tactaattgc agcacaccgt ggtacaaacg gaggaaatat attacaaaac acatcaaaag
      181 cctatttgaa ttccatacgc cataacgcag atatgtttga ggttgatgta attcgttcaa
      241 aagatggaga attttttgca tttcacgatg ggcaagaacc tttagtattt ggtgaaaaaa
      301 ttgatattag aactttgagt tctgaagaga tccaaagaaa ggaatgtttt aattcactga
      361 atgaacccat attacaaaag attgaaaaaa tttctgatgt attaaaaaat tttgagggac
      421 agtctttaat aaatatagat agaagttggt tttactggga taccttccta gataagttaa
      481 aaacatatcc atctttgaat caagttcttt taaaatcacc tgtaaaaaaa gaattattgg
      541 aaatgcttag agactctggt ttgaatatta tgtatatgcc aattatcaaa acaattgaag
      601 agttagattt tgttctctca tttgaaggaa taaatatagt agctgtcgaa cttgtattcc
      661 aagatttaga aaatccaatc ataagtaaga aagtaattga tgatttacat gaaaaaggat
      721 tacttatttg ggttaatgct ttaaccttaa gtgattcaat tattctttcg gctaagattg
      781 atgatgatac agctattgct catgatggcg aatcttgggg gaaattggtt tcaataggat
      841 ttgatattat tcaaacagat tggccattat tactttatca atatctagtt gaaaaaaata
      901 aaaaaataaa aaaataaaaa aataaaaata aaggagaact atcatgttca aaaactttaa
      961 aaagattgca ttcacttctt cactaatttt acttgctgct tgctcaaaca atgcttcaaa
     1021 tacaaatcag tctactgatg aaggaagtgt tgataaatct caagaaattg taatctatac
     1081 aaattcggct tctaatggac gtgcagattg gttacaaacc aaagcatcag agcaaggata
     1141 caatcttcgt ttggtagata tttcaggtgg agaactagct gaccgtttga ttgcagaaaa
     1201 gaataatgct gtggctgata tggtaattgg attaaataaa ttagaattta accgtattaa
     1261 agctgaaaaa cttcttgtaa aatactcacc aaaatgggct gatgaagtag atagctcttt
     1321 gggagattct gaagggtatt attcaccaat tgtaaatcaa ccattagttt tgattggtaa
     1381 taaagatgct aaaatgccat ccgactggac agattttact gattcatctt ataaaggtaa
     1441 atatggtatt tcaaaattaa gtacaggtac atctaagaac atctttgcaa gtattgtttc
     1501 gagatataaa gatgaaaaag gtgagttagg aatatctgat gaaggttgga aagttgcaaa
     1561 agcttacctt aaaaatgcac acgtttatgc agaaggtgaa gactatatct cttcaattat
     1621 ggataataat aatgagctaa aatatagtat gatgtgggga tctggtgttc tacaaaatca
     1681 aaaagaacgt gaatataaat tccaagtaat gtcaccaaaa gttggtgttc cttatgtaac
     1741 tgaacaagtt gggattttaa atacaagtaa gaagcaagca ttattaaaag aatttgtaga
     1801 ttggtttggc tcttcagaac ttcaaaaaga atggtctgat aaatttggtt caattccagc
     1861 taataaaaaa gctctagagc aagcaaaaga tgaactcaaa cagtttgcta atagtgttaa
     1921 accacaagaa cttgactggg agtttatcgg aaaaaacatc gattcttgga ttgaaaaagc
     1981 acagcttgaa tttgttgaac agtaatagtt aggattaagt gatgattaca tttaaggata
     2041 ttcaaattaa gtataatgat tttattgcca tcgataatct caatttaaca atcaatgaag
     2101 gagagttttt cacattttta ggaccaagtg gttgtgggaa atcaacaact cttcgtgcac
     2161 tagttggatt tttggagcct tcacaggggc aaatactagt tgataatcaa gatattacga
     2221 atttagatcc ggaaaaacgc gaaattggta ttgtgtttca aagttatgca ttattcccaa
     2281 caatgactgt ttttgataat attgcttttg gtctaaaagt taaaaaagtt tctcctgaaa
     2341 ttattaaagc taaagttcat gaaattgcga aaaaaattaa tatctcagac gagcaactaa
     2401 accgaaatat ttctgaatta tcagggggac aacaacagcg tgtagcttta gcacgtgcat
     2461 tagtattaga accaaaaatt ctttgtttgg atgaaccgtt atcaaaccta gatgccaaac
     2521 tacgagtttc gttgagaaaa gaattgaaac gattgcaaaa agaactagga atcactactc
     2581 tttatgtcac acatgatcaa gaagaagcat taacattatc agataggatt gctgtgttta
     2641 ataatggatt tattgagcaa gttggcacgc cgtatgatat ttataatcaa tccgaaactc
     2701 aatttgtctg tgattttatt ggctcaatca ataaaattag ccaagaagtt cttaaaaaat
     2761 tacaaggcga gaataaatac tttaaagaaa ctgaaggata catacgctta gagcgtgtta
     2821 agttagagaa aacttcacct caagatttat ctataacagg agtaattagt gatattgagt
     2881 ttaatggtgt acttattaag tataaagtag acttgtcgaa tagtgaaagt attcatatta
     2941 tcgaaaagaa tgatggacta tcacgtcata taatcgaaga aaaagtcact atgtacatta
     3001 atccgcgtga tataatgcaa ttttaaggag attgtgcatg agaaagagtc taaactggaa
     3061 agattggctc ataagattag gagttttatg gctaatcttt gccctgatta tttatccaaa
     3121 tattgaactt ttgtctggag tgttttataa aaatggttca tttactctag aggcattcaa
     3181 taagattata cactctcaga gagcgatgag tagtatattt aatagcttta ttttggcgat
     3241 ttcaatggtc tttactgtaa atattgttgg gacattgatt gttctactca cagagtactg
     3301 ggatattagg ggttcaaaaa tacttaaatt aggttatatg agctctctag tatatggagg
     3361 aattgtatta gcgacaggat ataaatttgt ttatggcgct aatggtcttg taactaaaac
     3421 gctctcaagt ataattccag gtcttgcccc taactggttt caaggatttg gtgcagtatt
     3481 gtttattatg acatttgctt gtacctcaaa tcacataatg tttttaacaa atgcagttcg
     3541 tagtgttgat tatcatacaa ttgaagcagc taaaaatatg ggtgcaagtc ctttaaaagt
     3601 tttctttagt gtggtttttc caacttttaa acctacgtta tttgccttaa ccatcttaac
     3661 ttttttgaca ggtctttcag cagtttctgc tcctttgata gtagggggga aagattttca
     3721 aactattaac ccattgatta tcagtttcgc taaaactaca agttcgagag atttagcagc
     3781 tttactagct atcatgttag gtttagcaac tattctatta ttgacacttt tgaatcatgt
     3841 cgaaaaagga ggtaattatg tatctgtttc gaaaaccaag gctagtatta agaagcagat
     3901 aatttcttct ccattatgga atactcttgc tcacattgtt gcgtatgtat tgtttgcaat
     3961 ctatatgtta ccaatagttt tgataattct atactcgttt acagactcgt tgacgatcaa
     4021 gacgggaact ttagatctat ctaaatttac gttagcgaac tatgctaatt tatttacaga
     4081 tgctcaatca tttcgtcctt acctagtcag cgttgtttat gcaattttag ctgcggtaat
     4141 tgctacaatt atagcaatag taatttcacg tattgtacat aaaaacaaga gtaagttcga
     4201 taaattcttt gagtatggtg cactaatacc atggatattg ccaggtacat tgattgcact
     4261 aggattaatg ttcacttata atatacctca tttaatacta tttaatttag ttttagtagg
     4321 aacagtaatt attttactta ttgcatatac tattcaaaaa ttaccatttt cttatagaat
     4381 gattcgggct gtatttttca gtatagataa tgatatggaa gaagcagcac gtagtatggg
     4441 tgcatctagt ttctacacta tggtgcgagt tattataccg tatattttac cagtcgtatt
     4501 atcagtagtt gtgttaaact ttaattcttt attatctgac tatgacttat ctgtattctt
     4561 gtaccatcca cttttccaac cattgggaat cgttattaaa cagtctactg atgaaacagc
     4621 aactttaaat gcacaggcaa tgatgtttgt ttattctgta attttaatga ttatgtctag
     4681 tgcagctctt tatttatcaa gcctattcca aggtaaacga ggtaagagat aatatgaatc
     4741 tttcatacga actgagtatt tgggaaatac ttcttaggtg ctttttagcg attcttttcg
     4801 gtggcattgt tggctatgag cgaggagtca aaaaccaagc agcagggatt agaacctact
     4861 tactagtttg tttgggaact tgtgttgtaa tgatgacaaa tcagttcatc actagtcgtt
     4921 atggtagcgg tgatcctagt cgaatgggag cccaagtaat tagtggcttg ggtttcctag
     4981 gggcaggaac aatcatggta actaatcaaa aagttaaagg tttaacaaca gcagctggat
     5041 tatggtcttc agcaactatt ggtttagcta taggcattgg tttttatgaa ggtgctattt
     5101 tagccggagt tgtactcata gcagttttaa ctctatttac tcctcttaaa gattatttaa
     5161 actcgaaaac taaaattgct gattactact tggtttttag ttctttagaa ggt
//
LOCUS       DAVLMQ010000090         5084 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000090 DAVLMQ010000000
VERSION     DAVLMQ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5084)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5084)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5084
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.091"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            129..1622
                     /locus_tag="VXF95_002060"
     CDS             129..1622
                     /locus_tag="VXF95_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1082542.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            1635..2756
                     /locus_tag="VXF95_002061"
     CDS             1635..2756
                     /locus_tag="VXF95_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1082543.1"
                     /translation="MKKVKLGEVCEILSGYAFKSSQFNDNKIGLPLIRIRDVERGFSD
                     TYFEGTYPEEYLIKNGDLLITMDGSFILKKWEGDLALLNQRVCKIKITDKSVDEGYIS
                     WLIPKFLKEIEDKTPFVTVKHLSVAKIKDISFVLPNKLEQKLIAKKLNTISQIYDFRK
                     IQSEKFNELVKSRFNEMFGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLN
                     TKNVTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTIRGTVGNVAYYDELIKYKHL
                     RINSGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLA
                     LQNEFADFVVQVDKSQLAIQKSLEELETLKKSLMQEYFG"
     gene            2816..3052
                     /locus_tag="VXF95_002062"
     CDS             2816..3052
                     /locus_tag="VXF95_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HEV1082544.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
     gene            3049..3462
                     /locus_tag="VXF95_002063"
     CDS             3049..3462
                     /locus_tag="VXF95_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HEV1082545.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSPSALNMIVNLPEQ
                     FVFGKPLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSITVEEA
                     VKMCVTIAVEALTDEKMTSYSKWISEHSVREKVKK"
     gene            3580..4545
                     /locus_tag="VXF95_002064"
     CDS             3580..4545
                     /locus_tag="VXF95_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1082546.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            4579..>5084
                     /locus_tag="VXF95_002065"
     CDS             4579..>5084
                     /locus_tag="VXF95_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HEV1082547.1"
                     /translation="MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGIN
                     YYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKY
                     VVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLGEQQRIASELDLLSKLILRRQE
                     QLEELNLLV"
BASE COUNT         1826 a          739 c          986 g         1533 t
ORIGIN      
        1 gtttgaagag attttcgaag agtataaaat attcaggtga cgcatagata tagttaattg
       61 aagctttgtt tgaaatctga taaaataatg atattactaa gttttaaaaa ctaaagaaaa
      121 gggaagatat gattacaggc gaattaaaaa ataaaatcga ccagctgtgg gaaattcttt
      181 ggacagaagg aaacgcaaat cctttaacaa atattgaaca gttgacttat ctcttattta
      241 tgaaagattt ggatagtgtc gagcttggac gtgaaagtga tgctgaattt ctagggattc
      301 cttatgaggg agtttttcca aaagataaac ctgaataccg ttggtcaact tttaaaaata
      361 taggagatgc tcaggaagtt tatcgtttaa tgactcagga gatttttccg tttattaaaa
      421 atctcaaggg ggatacagat gatacagcct tttcacgata tatgcgagaa gctatttttc
      481 aaataaataa acctgctacg cttcaaaagg caatttctat cttagatgtt tttccaacta
      541 ggggattaga tgtagatttt gataatgaca aacaaagtat tactgatatc ggagatatct
      601 atgaatatct gttatcaaaa ttgtcgaccg caggtaaaaa tggacagttc cgtacacctc
      661 gtcacatcat cgatatgatg gttgagttga tgcaaccgac tatcaaagat atcatctcag
      721 atcccgctat gggttctgct ggcttcttag tatctgctag ccgttactta aagcgtaaga
      781 aagatgaatg ggaaaccaat acagataata tcaatcattt tcataatcag atgtttcatg
      841 gaaatgatac ggatacgact atgttgagac ttggggcgat gaacatgatg ctacatggag
      901 tagaaaatcc acaaatcagt taccttgact cgctgtctca agataatgaa gaagccgata
      961 aatatacttt ggttttagca aatcctcctt ttaagggctc acttgactac aattcaacct
     1021 ctaatgacct tcttgcaacc gtaaaaacca aaaaaacaga attactcttt ctttctcttt
     1081 tcttgcgaac tttaaaacca ggtggacgag cagcagttat cgtacctgat ggtgtccttt
     1141 ttggttcgtc taaagctcat aaaggaattc gtcaggaaat tgtagagaat cataagcttg
     1201 atgctgtaat ctcaatgcct agtggtgtgt tcaagcctta tgctggagtt tcaactgcta
     1261 ttctcatctt tacaaaaact ggtaatggtg gtactgacaa agtctggttt tacgatatga
     1321 aagcggatgg tttaagtttg gatgataagc gacaaccgat tagcgacaat gatattccag
     1381 atattatcga acgctttcat catcttgaaa aagaagcaga acgtcagaga acggatcaat
     1441 ctttctttgt tccagttgct gagataaagg aaaatgatta tgatttgtct atcaataaat
     1501 ataaagagat tgagtatgaa aaagttgagt atgaaccaac agaagtcata ttaaagaaaa
     1561 tcaatgattt agaaaaagaa attcaagctg gcttggctga attggaaaaa ttactcaagt
     1621 agggaggtgg ctgtatgaaa aaagtgaagt tgggggaagt ttgtgagatt ttatctggtt
     1681 acgcttttaa atcatcacaa tttaatgata acaaaattgg tctcccctta atacgaattc
     1741 gagatgtaga aagaggtttt tctgatacct actttgaagg aacttatccc gaagaatatc
     1801 ttattaaaaa tggagactta ttgattacaa tggatggcag ttttatattg aaaaaatggg
     1861 agggggattt agcgctactt aatcaacgtg tctgtaaaat taaaattacg gataaaagtg
     1921 tagatgaagg ttatatatct tggttgattc ctaaattttt aaaagaaatt gaagataaga
     1981 ccccttttgt tacagtgaaa catctttcag tagctaaaat aaaagatatc tcatttgtat
     2041 tgcctaataa actagaacaa aagctaattg caaaaaaact aaatacgata agtcaaattt
     2101 atgattttcg taaaattcaa tcagaaaaat ttaacgagct cgtcaaatcc cgatttaacg
     2161 agatgtttgg ggaaaataaa atatttgaaa gcattgataa cttatttgat attatagatg
     2221 gtgatagggg caaaaattat cctaaatcag atgagttgtt tagtgaggag tactgtttat
     2281 ttttaaatac aaagaatgtt actaaaaacg gattttcatt cgatacaaag caatttatca
     2341 ctaaaacaaa ggataaatta cttcgaaaag gcaaacttga gcgttatgat atagtcttga
     2401 caataagagg tactgttgga aatgtagcgt actacgatga attaataaaa tataaacatt
     2461 tacgtataaa ttcaggtatg gtaatattac gtcccaagac accaaatcta aatcagaaat
     2521 ttattatcca tgttttaagg aataataatt atagtcgagt gatatcagga agtgctcagc
     2581 ctcagttacc aattacaaaa ttaaaaaaaa tacttctccc cctcccccca ctagccctcc
     2641 aaaatgagtt cgcagacttt gtagtccagg tcgacaaatc acaattggca atccaaaaat
     2701 ctctggaaga acttgaaact ttgaagaaat ctctgatgca ggagtatttt ggctgatatt
     2761 ctgccattgt aattacggta atgatttgtt ataatacttc aaaggaggaa atcagatggt
     2821 agtaaaaaca agaaaacaag gaaattcaat caccattacg attccaagtg aatttaatat
     2881 tccaagtggt gttaaatacg aagcgaaatt gttaccaagt ggtgagatta tctttactcc
     2941 tgaagaattg gggcagcagg tttcttatgt atctgatgat gcctttgact taaatttaga
     3001 taaaatattt gacgaatacg acgatgtttt caaagctttg gtggaaaaat gacaatctat
     3061 ttgacagaaa agcaaattga aaaaataaat gctttagcaa ttcaacggta ttctccaaat
     3121 gagaaaattc aaacagttag tccttctgcc ttaaatatga ttgtgaactt accagaacaa
     3181 tttgtctttg ggaagcctct ttatccaaca atttttgata aagcaacgat actatttgtc
     3241 caattgataa agaagcatgt ttttgctaat gctaataaaa gaactgcttt cttcgttttg
     3301 gtcaaatttt tacaattaaa cggctatcgt ttttctataa cggtagaaga agcagtaaaa
     3361 atgtgtgtaa ccatcgcagt agaagcttta actgatgaaa aaatgacaag ctactccaaa
     3421 tggatttctg aacattctgt tagagaaaag gtcaaaaagt aacctagtat gctggatttg
     3481 aatgagcaca agaaaataaa tgaacagaca atattagaat tctgtaatgc agaaactgat
     3541 attgtctctt tttattgatg aataagaaag tgagaaatta tggaatcaaa agttacaatt
     3601 atcatgcaag aaatgttacc tcttttaaat aatgaacaat tactagcgtt gagagagagt
     3661 ttagaacatc atctagtaga cggaaaaaag cagcagaagt attcgaataa taacctgttg
     3721 caactattta ttaccgccaa gcaggtagag ggctgtagct caaaaacaat tcgttattac
     3781 cagaggacga ttgaaaactt gtttaatgct attaaagagt ctgtgacaca actcacaaca
     3841 gatgatttaa ggagttattt agcaaattac cagtctgaaa aggattgtag taaggcaaat
     3901 ttagacaata ttaggcgtat attgtcttct ttttttgctt ggcttgagca agaggaatat
     3961 atcattaaaa atcccattcg acggataaag aaaattaaga ctgagcaaaa tgtgaaggaa
     4021 acttatactg atgaacattt ggaaattatg cgtgataact gtgaaaattt gagagatttg
     4081 gcaataatag acctactagc atcgacaggt atgcgtgtag gggagcttgt acagttgaat
     4141 cgttcagata ttgattttga aaacagagag tgtgttgtct ttggtaaagg aaagaaggag
     4201 agaccagtat attttgacgc tcgtacgaaa attcatttaa gaaactatct taacgacaga
     4261 aaagatagtc accctgctct ttttgtaacg ttagttggaa aagtccagag gcttggaatt
     4321 gctggtgtag agattcgctt aagaaagtta ggagacaaac tcggtataca aaaggttcac
     4381 ccacataagt tcagaagaac tttagcgact aaggcaattg ataaaggtat gcctatcgaa
     4441 caagtccaaa aactgctagg tcatagcaag attgacacaa ccctggccta tgccatggtc
     4501 aatcaaaata atgtcaagca ttcacaccaa aaattcatct cttaaaagca aatcccgata
     4561 ttccgaggag gtggttgcat gaagaaagtg aaattagggc aagtggctac ttttatcaat
     4621 ggctatgctt ttaaacctca agattggtca tctgaaggga aagagattat cagaatacag
     4681 aatctgacta aaacttcaaa agggataaat tattattcgg gtacgattga taaaaaatac
     4741 attgttgaag ctggtgatat tcttatttcg tggtcgggta cattaggggt ttttcagtgg
     4801 tgtggaagat ccgcagtgtt aaatcagcac atttttaaag tggtttttga taagatagat
     4861 atagataaat cgtattttaa atatgttgtt gaaaaaggtt tacaagatgc tgtaaaacat
     4921 actcatggtt ccacaatgaa acatttaact aaaaaatatt ttgataatat tatggtttca
     4981 tatacaaatt tgggagagca acaaagaatt gcaagtgagc tggatttgtt aagcaagctg
     5041 attttaagga gacaagaaca acttgaagag cttaatctac ttgt
//
LOCUS       DAVLMQ010000091         5048 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000091 DAVLMQ010000000
VERSION     DAVLMQ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5048
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.092"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..903)
                     /locus_tag="VXF95_002066"
     CDS             complement(<1..903)
                     /locus_tag="VXF95_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1082548.1"
                     /translation="MLSLDQIHLLLNTPEDEFHDFKQKWHHSKTELVRDILNFVNTSH
                     HEDCYIIFGIDNITLDIIGVNNDDNRRNEEDLTDLLHKLFISTNNQIKISIQTETIDN
                     KEIDILIIHDTDKVPVFLTKDYKPKKDTALPKGLIYARNGSINTPKDSSAPFELINEL
                     FQKFNHTDLNIKEQYFHVLKDYKNWFFIENEDGRFFIYNPNPDFYIKLNDDDANRFKT
                     MSYSLNQYQTNIDWQLVQLRYRHLTIDECMAMYLDQGNCLVPSPEVESFKIDYQETIY
                     YHCLYKNTLKYQLLKVFSSIPGLEK"
     gene            1265..1621
                     /locus_tag="VXF95_002067"
     CDS             1265..1621
                     /locus_tag="VXF95_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082549.1"
                     /translation="MKRDVRDIRKQFRLTEAEEKQILALMRERGETNFSDFLRKSLLS
                     SDLQKQMETWFALWQSQKLEQISRDVHEVLILAQSERQVTQEHVSILLTCVQELIQEV
                     ANTIPLSKEFREKYMR"
     gene            1626..1991
                     /locus_tag="VXF95_002068"
     CDS             1626..1991
                     /locus_tag="VXF95_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HEV1082550.1"
                     /translation="MEHRYRTNLKKVFLSDSELNQLNINIDQSGCKSFSEYARRTLLD
                     PGMNFITIDTNGYQDLVFELKRIGNNINQIARSVNQSQLISGEELQELKKGIGELIKE
                     VDKEFNLQAQKLKEFHGHH"
     gene            1978..3801
                     /locus_tag="VXF95_002069"
     CDS             1978..3801
                     /locus_tag="VXF95_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002917262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HEV1082551.1"
                     /translation="MVITKHFAIHGKSYRRKLIKYILNPEKTNNLALVSDYGMKNFLD
                     FPSYEEMVQMYHENFISNDTLYDFRHDRMEENQRKIHAHHIIQSFSPEDHLTPEQINR
                     IGYETVKELTGGKFRFIVATHVDKDHLHNHIIINSVDSNSDKKLKWDYKVERNLRMIS
                     DRFSKIAGAKIIENRYSHQRYEVYRKTNHKYELKQRLYFLMEHSRDFEDFKKNAPLLH
                     VEMDFRHKHATFFITDSTMKQVVRGKQLNRKQPYTEEFFKNYFAKREIESLMEFLLLK
                     VENMDDLLQKAKLFGLTINPKQKHVSFQFAGVEVKETELDQKNLYDVEFFQDYFKNRK
                     DWQAPETEDFVQLYQEEKLSKEKELPSDEKFWESYQEFKSNRDAVHEFEVELSLNQIE
                     KVVDDGIYVKVKFGIRQEGLIFVPNMQLDMEEDKVKVFIRETSSYYVYHKDAAEKNCY
                     MKGRTLIRQFSYENQTIPLRRKATVDMIKEKIAEVDALIELEVENQSYVTIKDELVHE
                     LAASELRINELQERMSTLNQVAEYLLASVESKQEMKLNLSKLNITENISANIVEKKLK
                     SLGNQLELERGRYEKMVVRLDKFINRLNTGLSKGDGIDFQK"
     gene            3915..4781
                     /locus_tag="VXF95_002070"
     CDS             3915..4781
                     /locus_tag="VXF95_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000537001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082552.1"
                     /translation="MGTLLATRLKNRRKELKMSQRELAEGICKQGQISRLESGEFTPG
                     ADFLHALAKKLKVSMDYFFDEQVVEEVNELSEFKKLAQTFITNRNYESLKYIYELENV
                     KAHRLSLADKFYMEWIKSLIDFYFYGQKEEAITRLENMLPQLNVSDLNYLQVSNTLFN
                     FYYDIEDLERFNEIRDKLEHQVNQLNLNTIEELELSIKFNYNVCRYLWLQKNIEEAIT
                     KITATIKQCKEYRTTYLLADLYLLMGSVSENFSSKSSVKEYFETAHFLYKLEENMSMA
                     LKVEHYFADITE"
BASE COUNT         1774 a          748 c          980 g         1546 t
ORIGIN      
        1 tttttcgaga ccaggtattg aagaaaatac tttcagcaat tggtacttta aagtattttt
       61 gtataagcag tgataataaa tagtctcctg ataatctatt ttaaaacttt ctacttcagg
      121 ggaagggact agacaattac cttgatctaa atacatagcc atacactcgt caattgtaag
      181 atgacgatat cgaagttgta ctaattgcca atcaatatta gtctggtatt gatttaaact
      241 ataagacata gttttgaaac gatttgcatc atcgtcgtta agtttaatat aaaaatcggg
      301 attaggatta taaataaaaa atcttccgtc ttcattttca atgaagaacc aatttttata
      361 gtcttttaaa acatgaaaat actgctcttt gatatttaag tcggtatgat taaacttttg
      421 aaacaactca tttattaact caaaaggagc agaggagtct ttaggggtat ttatagagcc
      481 atttctagca tatattaatc cttttggtaa tgcagtatct ttcttaggct tataatcttt
      541 tgttaaaaat acaggaactt tatctgtatc atgaataatt aagatgtcaa tttctttgtt
      601 gtctatagtt tcagtttgta tgctaatttt aatttgatta tttgttgata taaagagttt
      661 atgtagtaaa tctgttagat cttcttcatt tcttctatta tcatcattgt ttacaccgat
      721 tatatctaaa gtgatattat caattccaaa gatgatataa caatcttcgt gatgtgatgt
      781 attgacaaaa tttaagatat cacgcaccaa ttcagttttt gaatgatgcc atttttgttt
      841 aaaatcatga aactcatctt cgggtgtatt caatagtaag tgtatttgat ctagactcag
      901 catttttatt tctccaaata ttagtttaca gaaattttat catagaatca gagaaagtca
      961 atcataacta tattagctgt gatacctttt tcaaatcttc cctgttatcc taatatcatt
     1021 catagaaaat caatttttga ttttctatgg gggtttgggg gcgaagtcac caagttatct
     1081 tatcgttggc tgtcaaaact agaaagtttt gataggctgg cgatatgatt tttgggatat
     1141 tgtggacaca atatctgagc tcgcaaagcc ttacaagaat gaaaatcagt tgttggaaaa
     1201 gtgtactgac attgtatggt agctcacatt gtcagtacaa gtattttgga aaggaagtag
     1261 cagtatgaaa cgagatgtgc gtgatattcg gaaacaattt cgtttaacag aagcagaaga
     1321 aaagcaaatt ctagctttga tgagagagcg gggagagact aatttctctg attttcttcg
     1381 taaaagttta ctttcctctg atttacaaaa acagatggag acatggtttg ccctctggca
     1441 atcccaaaaa ctagaacaaa tcagtcgtga cgttcatgaa gttttaatct tggcacagtc
     1501 agaacgtcaa gtcacccaag agcatgtatc tattctctta acgtgcgtgc aggaattgat
     1561 tcaagaggtt gcaaacacca tacccctcag taaagaattt cgtgagaagt acatgaggta
     1621 agcacatgga acatcgttac cgaaccaatc tcaagaaagt gtttttgtct gatagtgagt
     1681 tgaaccaact aaatataaat atcgatcaaa gtggttgtaa atccttttct gaatatgcga
     1741 gacgaactct actcgatcct ggtatgaatt ttatcacgat tgacacaaac ggttaccaag
     1801 atttagtgtt tgagttaaag aggattggca ataatatcaa ccagattgct cgaagtgtta
     1861 atcaatctca gttaatttct ggtgaagaat tgcaggagtt gaaaaaagga attggtgaat
     1921 tgataaaaga agttgataag gaatttaatc tgcaagcgca gaagctaaag gagttccatg
     1981 gtcatcacta aacactttgc cattcacgga aagagttacc gcagaaagct tatcaagtac
     2041 attctcaatc ctgagaaaac caataatctt gccttggtgt cggactatgg catgaagaat
     2101 tttctggact ttcctagcta tgaggaaatg gtgcagatgt atcatgaaaa tttcatcagc
     2161 aacgatacgc tttacgattt tcgccacgac aggatggaag aaaatcaacg aaaaatacac
     2221 gctcaccaca tcattcagtc tttctcgcca gaggatcatc tcactcctga acaaatcaat
     2281 cggataggtt atgagactgt gaaggaatta actggtggca aatttcgttt tatcgttgcg
     2341 acccatgttg ataaagacca cctgcacaat cacatcatta tcaattcagt agatagcaat
     2401 tctgacaaaa agctcaagtg ggactacaag gtggagcgaa atcttcgcat gatttctgac
     2461 cgtttttcta aaatcgcagg tgctaaaatc attgagaacc gctattctca ccagcggtat
     2521 gaagtctatc gtaagactaa tcacaagtat gaactcaagc agcgactcta ttttttgatg
     2581 gaacattcta gggactttga ggatttcaaa aagaatgctc cgctactaca tgtggagatg
     2641 gatttccgtc acaagcatgc cacctttttt attacggact caactatgaa acaggtggtg
     2701 cgtggcaagc aactcaatcg caagcagcct tacacagaag aattttttaa gaactacttt
     2761 gccaaaagag aaatagaaag tctcatggaa tttttattgc tgaaagttga gaatatggat
     2821 gatttacttc agaaagcaaa actttttgga ctaactatca atcctaaaca aaagcatgtt
     2881 tcttttcaat ttgcaggagt ggaggtaaag gagacagagc tagaccagaa aaatctttat
     2941 gatgtagagt ttttccaaga ttattttaaa aatagaaaag attggcaagc tccagaaact
     3001 gaggatttcg ttcaacttta tcaagaagaa aagttatcca aagaaaaaga acttccaagc
     3061 gatgagaagt tctgggagtc ctatcaagag ttcaagagta acagagatgc cgttcatgaa
     3121 tttgaggtgg agttgtcact caatcaaatt gaaaaagtag tggatgatgg aatttacgtc
     3181 aaggtcaagt ttggtattcg tcaggaggga cttatctttg tgccgaacat gcagcttgat
     3241 atggaagagg ataaggtgaa ggttttcatc agggaaacca gctcctacta tgtctaccac
     3301 aaagacgctg ccgagaaaaa ttgttatatg aaaggtcgaa ccttaattag acagttcagc
     3361 tatgaaaatc aaaccattcc attacgcaga aaagcgacag tcgatatgat taaagagaag
     3421 attgcggaag tggatgcttt gattgaactg gaagtagaaa atcaatctta tgtcacgatt
     3481 aaagatgagt tagtgcatga actagcagcg tctgaattga gaatcaatga gttgcaagaa
     3541 cgaatgtcaa ccttgaatca agtagcagaa tatctactgg cttcagttga aagtaagcaa
     3601 gaaatgaaat taaatctttc aaaactgaat ataactgaga atatcagtgc taatattgtt
     3661 gagaaaaaat tgaagagcct ggggaatcaa ctggaattgg aaaggggcag gtatgaaaag
     3721 atggtagtca ggctagataa atttataaat cgcttaaata caggactttc aaaaggagat
     3781 gggatagatt ttcaaaaata ggaatctagc caataattat atacaatgtg tatcttttgt
     3841 aaaatatatt tgaaatttag atttaatcat gttacaatta acattgaaat caaatagaaa
     3901 aggaagatgc aaacgtgggt acactattag caacaagatt aaaaaataga cgaaaagaat
     3961 taaaaatgtc tcagcgagaa ttagctgagg gtatctgtaa acaggggcaa attagtcgat
     4021 tagagagtgg agagttcacc cctggagcgg attttttaca tgcccttgct aagaaattaa
     4081 aagttagtat ggactacttt tttgatgagc aggttgtaga ggaagtcaat gagttatcag
     4141 agtttaagaa gttagcacag acatttatca caaatcgtaa ttatgaatct ttaaaatata
     4201 tatatgaatt ggaaaatgta aaagcccatc gcttatctct agcagataaa ttttacatgg
     4261 aatggataaa gtctcttata gatttttatt tttatggaca gaaagaagag gcaattacac
     4321 gattagagaa tatgctacct cagttaaatg tatctgattt gaactacctt caagtttcaa
     4381 acactctatt caatttttat tatgatattg aagatttaga acgttttaat gagattagag
     4441 acaagctaga gcatcaagtg aatcagctta atttaaacac aattgaagag ttagaactat
     4501 caattaagtt caattataac gtttgtcgat acctatggtt acagaaaaat attgaagaag
     4561 ctattacgaa aatcacagct acgataaagc aatgtaagga gtacaggaca acttatctat
     4621 tagctgattt gtatttattg atgggaagtg taagtgaaaa tttttcttct aaaagttcag
     4681 taaaagaata ttttgagact gctcattttc tctacaaact tgaggaaaac atgtcaatgg
     4741 ctttgaaagt cgaacattat tttgcagata taacagaata aggaatacgg tgttctagtg
     4801 agcatcgttt tttaaatcta atttgaatac aaaaaagtat taaataaaaa aaaataaaaa
     4861 aagattataa aaatacttga caagctaatt ttgaagtgat aaaataaatg caagaaaacg
     4921 aaaggagagg tatatgagaa gtttgtttag gaaaattgtt gctttgttag tcataggatt
     4981 aatcctatta gggactgctg gaggaactca agttcataag atggctagag ggattgatcc
     5041 aggtcctg
//
LOCUS       DAVLMQ010000092         4918 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000092 DAVLMQ010000000
VERSION     DAVLMQ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.093"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(231..860)
                     /locus_tag="VXF95_002071"
     CDS             complement(231..860)
                     /locus_tag="VXF95_002071"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HEV1082553.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIRNEEEFQQSKVEYVDYVGVGPVFGTQSKDDAGGTIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNMDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(862..1644)
                     /gene="thiM"
                     /locus_tag="VXF95_002072"
     CDS             complement(862..1644)
                     /gene="thiM"
                     /locus_tag="VXF95_002072"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HEV1082554.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEIAEKHPNGHLPGTFKVEFINALYEITDEDVKEFKRVK"
     gene            complement(1932..2600)
                     /locus_tag="VXF95_002073"
     CDS             complement(1932..2600)
                     /locus_tag="VXF95_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HEV1082555.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENDYLEVTLHPVTKAFQDLMYSAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAEWVQFLVDELNRVGKNREDLTELQQRWNQAVALELAFFDI
                     GYDV"
     regulatory      complement(2815..2903)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(3155..4291)
                     /gene="lctO"
                     /locus_tag="VXF95_002074"
     CDS             complement(3155..4291)
                     /gene="lctO"
                     /locus_tag="VXF95_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HEV1082556.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
BASE COUNT         1504 a         1061 c          770 g         1583 t
ORIGIN      
        1 taaagcaccc caaatgtctt tattatttaa ttatgtgatt attataacac acattttata
       61 ctagttcaag aaattgaact ggaaatacag ccttgcactc acaaagacag cagatttttc
      121 ttttgcaaaa aacaaatgac ctgtttgatg aattagccat tcaagctgaa tctggacata
      181 gctttttaaa aaaggaaaat cctacttact tagaatccaa ggatagatat ctattgttca
      241 ctcatttccc gaacagtttt ttctatattt tttgcatacg atattgccga aatgattgaa
      301 acgccatcca tattggtctt tataatgtct ttaatatgtt tcgtctgtat cccaccaatt
      361 gcaactaaag gcatttgtgg caatagtttt ctcatcaatt caagaccttc ataacctata
      421 gtaccaccag catcatcctt tgactgggta ccaaatacag gcccaacacc tacataatct
      481 acatattcaa cttttgattg ttgaaattct tcttcgtttc ttatagaaag accaattatt
      541 ttatctggca tcaattttct aatttcatca acaccaatat catcttgacc tacatgtacg
      601 ccatcggcgt caatttccat tgctaaatct atatcgtcat taacgataaa tggaacattg
      661 tattttttac aaagttcttt aatttggata gctagctcaa gtttttctaa gccttctaaa
      721 gcaccctcac ctttttctcg aaattgaaat aaggttatac caccttttaa ggcttcctca
      781 acgactgtat atagattttt tccttggcaa gtagtcgttc cacaaataaa atatagtttt
      841 agtaattctt tatgaaacat cttacttcac tcttttgaat tcctttacat cttcatctgt
      901 aatctcgtat aaggcattta taaattcaac tttaaatgtc ccaggaagat gtccatttgg
      961 atgtttttct gctatttctc cagcgatatt gtaaaccaac attgctgttt ctaatgattt
     1021 caattcttga cctttttcta gtccgataaa gcttgctact acagctccta ataagcatcc
     1081 tgtcccaatg actttcggca tcatagcact accattatga atcgttacca cttctccatt
     1141 aacagcaatg gcatccactt cacctgttac tactattgga atattgaact tctcatttgc
     1201 tgctagagca atttcgtcaa tattatctac gcccgcacta tctactcctt tagatgccac
     1261 atctattcct actaaagagg caatctcgcc agcatttcct ctaatcgctg ctagtttata
     1321 attgttgatt agatcatctg ctactttttt tctatattct cctgctccac aggctacagg
     1381 atctaaaact gctgggacat tatatttctc cgcaattttc agagcagctt ggtataattt
     1441 ccaattttca tctgtcaatg ttcctatgtt tattaataaa ccaccagcat actttaacaa
     1501 atcctctaaa tctgctggaa actcactcat ggctggtgag gcgcccagtg ctactaatcc
     1561 atttgctgtg aaatttttta ctacatcatt ggttatacaa atgaccaatg gtgctttttc
     1621 ttttaataat tttaaacttg tcatattgaa atccttcctt ttcactttat acgatctact
     1681 gatttcgatt tatttctatc tttcgttaag aatttttttc atttacattg aatgatttat
     1741 actcaatgaa aatcaaagag caaactagga ggctaaccgc aggttgctca aaacactgct
     1801 ttgagcctgt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgtggata
     1861 gaactgacgt ggtttgaaga gattttcgaa gagtcttacc tcatcaaatt tgtaaatatc
     1921 atgagccttc tctagacatc gtaaccaata tcaaaaaaag ctaattctaa agcgactgct
     1981 tgattccagc gttgctgaag ttctgtcaaa tcttctcgat ttttaccgac acgattgagt
     2041 tcgtcaacca gaaattgaac ccactctgca aagaaaggac ctctgtggag attgatccat
     2101 tccgaatgaa tatagacttc aggtaaagcc aaatctttag aaccccagtc taaatagaga
     2161 ccttctgcaa tgaccagcat gaccaaaaga tgggcatagt ctgatgaagc caccgccgaa
     2221 tacattagat cctgaaaggc ttttgttaca gggtgcaaag tcacttctag atagtcattc
     2281 tctgctactt ttaactcttt aaaagccttt tggaaataac catcttcatc tgcttcaaga
     2341 aagcctagtt gcttggcaaa acgaagcttg gattcaagtt tatctgcgtg agctacgcag
     2401 gcacccagca tggataagaa ggcatcaaag aagtgataat cttgaatcag atagtccttt
     2461 aagaccttat tctcaattgt ccccgcaaaa agttccttaa caaaacgatg attgattgca
     2521 gcctgccaat ccttctgact gctttttaat aattctccaa cagtcaaacc tggctgaaat
     2581 gcatagtctt gtgtttccat atttacttct cctctcttta cttgttagta attaataaaa
     2641 caccaagaaa tatcaagcaa aatcgtaatt ccacttgatc cttttaaaac acatcgagag
     2701 tatttgcaga gagctaacta aacaagccta tccagtttat ataaacaaaa aactccaatt
     2761 acaatcaaga attagagttg acttacaaga ttagatcgtt catttcgcca tacgaaaaaa
     2821 cgtttcacat ttcccttcgc cagtcttaac tgtatcaggt tcaatgggta tcatctcagc
     2881 ttaaagcacc ccaaatgtct ctattattta attactgaac cagtatagca aaaaatgaaa
     2941 gccctagcaa gatatttgac cgaaaaatat ctttatatag tagattgaaa ctagaatagt
     3001 acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatt gatttgtcct
     3061 attcttattt catttcacta tagttttcga tagcaattta ttcttccaat acacgaagaa
     3121 aaacctccac attcagtgga ggcaatctgt tttatcaata caattttaag tcacgagggt
     3181 caactgggaa ggttgggttg tatggattgt gacggagctt aaagtgtttg acatcttcaa
     3241 tggtctgagc tccagacaat tgcataactg tcttcaattc cgcattcaag tgttcaaaga
     3301 cttgacgcac accgacacta ccaccgagag ctaagccata aataacaggg cgaccaatag
     3361 ctaccaagtc tgctcctgaa gccaaggctt taaagacgtg ttgaccacga cgaacaccag
     3421 agtcaaagac aatcggcaca cgtctatcaa ctgcttctgc cacttcttga agcgagtcaa
     3481 aggcagctgg tccaccgtcg atttgacgac caccgtggtt ggttacccag ataccagaag
     3541 ctcctgcagc aagtgaacgt tcaacgtcct cacggcattg tggtcccttg acatacacag
     3601 gaagaccaga gtattcagcg ataaattcta catcgcgtgg agacaagcgt tgtttagctg
     3661 atttgtaaac aaagtccatt gatttaccag caccttctgg caggtattct tcaacaatcg
     3721 gcatgccaac tgggaagaca aaaccattac gcttatccac ttcacgattc ccccctacag
     3781 tagcatctgc cgtcaagaca atcgctttat aaccttcagc cttcacacgg tccatgatgt
     3841 ggcggttgat accgtcatcc ttactaaagt aaaattggaa ccaatggggt gtcccttgaa
     3901 gggcttcaga aatctctgga aggtcaacag tagagtaaga gctggttgta taaagagaac
     3961 caaactcatg cacaccacgc gcagtcgcca cttccccctg ttcatttgcc aatttatgag
     4021 ccgcaacagg cgccataatg attggtgaag atagtttttc acctgcaaat tcaatctctg
     4081 tacttggatt ttcaacatcg caaagtgtat gaggaacgat gagtttgtgg ttaaaggcgc
     4141 ggatattctc tcttaaagtg aaagtatctt ccgccccact agcgatatag ccaaatgctg
     4201 ctttaggaat aacttgttgc gccattggct ccaaatcata ggtattgatg aagtctacat
     4261 gaccttctgc attgcttgtt ttatatgaca taaaatgccc tccttgatta agtaagcgtt
     4321 tgctttttac tacacaacta taataactct tttttcaatc attttcaaga gttttgctta
     4381 aaaaccatct tattttttca tacaatatac tagccctact ttccttaaac tctaaacctt
     4441 agtctatatt aagtgaatcg ttgagatttt ttgctgccag gcatttgaac tactttttta
     4501 tttgcggatt ctatctacta atactataaa aaaaacaagt gaataagaca ccagaacatc
     4561 ctctaatagg acctatggac ttatatcagt cccatatata ctgtttaagc aagatactat
     4621 cctagttgac gctaacttcc tatcccactt attaattttt tatttatagt gaatctgaac
     4681 aaatcaattg gggaatccaa gtcaatttct agtacttttt gaacagtttc agcgtactat
     4741 cgtaaaatga aataaaacat gcacaaattg attagggaat ttaaaccaat ttctaacaat
     4801 gtcttagaaa tcaaagtgta ctatttcaac ttcaatatac tacacttcat tttctcctta
     4861 aattcagtct ctttttgaat caaaaaatcc tctggtaaga gccagagggt aagaattt
//
LOCUS       DAVLMQ010000093         4667 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000093 DAVLMQ010000000
VERSION     DAVLMQ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4667
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.094"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            44..742
                     /locus_tag="VXF95_002075"
     CDS             44..742
                     /locus_tag="VXF95_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004241810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HEV1082557.1"
                     /translation="MGGKMRLLPIRKISRQSKRLALFLTFCAGYVDAYTFIVRGNTLV
                     AGQTGNVVFLSVELIKNNVSDVRDKVLTLLAFMMGVFLLTIYKEKLRIVKKPILSLIP
                     LAILSIIIAFVPQTVDNIYLVPPLAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLA
                     FGDYFRTKHTPFLREGFIFVSLLSSFVLGVVFSAYLTIFYHEKTILGVPIMMSVFYLS
                     MLFASWQKKVKEKA"
     misc_feature    807..894
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            930..1244
                     /gene="rplU"
                     /locus_tag="VXF95_002076"
     CDS             930..1244
                     /gene="rplU"
                     /locus_tag="VXF95_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HEV1082558.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYVEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     gene            1260..1604
                     /locus_tag="VXF95_002077"
     CDS             1260..1604
                     /locus_tag="VXF95_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HEV1082559.1"
                     /translation="MIQAVFERAEDGELRSAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            1621..1914
                     /gene="rpmA"
                     /locus_tag="VXF95_002078"
     CDS             1621..1914
                     /gene="rpmA"
                     /locus_tag="VXF95_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HEV1082560.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(2119..2324)
                     /locus_tag="VXF95_002079"
                     /pseudo
     CDS             complement(2119..2324)
                     /locus_tag="VXF95_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            2762..3679
                     /locus_tag="VXF95_002080"
     CDS             2762..3679
                     /locus_tag="VXF95_002080"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HEV1082561.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRTIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            complement(3772..4620)
                     /locus_tag="VXF95_002081"
     CDS             complement(3772..4620)
                     /locus_tag="VXF95_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1082562.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
BASE COUNT         1483 a          789 c          958 g         1437 t
ORIGIN      
        1 ttttttagaa agaaatggta caatatttct aagagaaaat acaatgggag ggaaaatgag
       61 gttattacct ataagaaaaa tatcacgtca gtctaaaagg ttagcacttt ttttgacgtt
      121 ttgtgctgga tatgtggatg cttacacttt tattgttcgc gggaataccc ttgtagctgg
      181 acaaactgga aatgttgtct ttctttcagt agaattaatt aaaaataatg tttcggatgt
      241 tagggacaag gttctcacct tgctagcgtt tatgatggga gtctttttat taacgattta
      301 taaggaaaaa ttgagaattg tgaaaaaacc tattctgtcc ttgattccct tggcaatctt
      361 atcaatcatt attgcttttg tgccgcaaac tgtggataat atctatctag tgccgccctt
      421 ggccttctgt atgggactgg tgacaactgc ttttggagaa gtgtcgggta ttgcctataa
      481 taacgctttt atgacaggga atatcaaacg gaccatgctg gcttttggag attatttccg
      541 aaccaagcac actccttttt tgcgtgaagg attcatattt gttagcctgc ttagtagttt
      601 tgtccttggc gttgtctttt cagcctattt gacgattttc tatcatgaaa agaccattct
      661 tggtgttcct attatgatga gcgtttttta cctcagcatg ctttttgcct cttggcagaa
      721 aaaagtaaaa gaaaaagctt gattttaggt gttattactt gtaagaaaat aggagatatg
      781 ctatacttga agagttgact atgcacgatc ctgtgcaacc gcacgaacat cgttgcttga
      841 ttattcaagt ttaagtggtt cgtcccacga tgctaggcga gtcttcacaa aaaatcgggg
      901 aaacccataa aaatcatagg aggtgcataa tgagcacata cgcaattatc aaaactggcg
      961 gaaaacaagt taaagttgaa gttggtcaag cagtttacgt tgaaaaattg aacgttgaag
     1021 ctggtcaaga agttactttt aacgaagttg ttcttgttgg tggtgaaaat actgttgtcg
     1081 gaactccact tgttgctgga gctactgtag ttggaactgt tgaaaaacaa ggaaaacaaa
     1141 agaaagtggt tacttacaag tacaaaccta aaaaaggtag ccaccgtaaa caaggtcacc
     1201 gtcaaccata tacaaaagtt gtcatcaacg caatcaacgc ttaattttaa ggagaacaca
     1261 tgatacaggc agtctttgag agagccgaag atggcgagct gaggagtgcg gaaattactg
     1321 gacacgccga gagtggcgaa tacggcttag atgtcgtgtg tgcatcggtt tctacgcttg
     1381 ccattaactt tatcaattct attgagaaat ttgcaggcta tgaaccaatc ctagaattaa
     1441 acgaagatga aggtggctat ctgatggttg aaataccaaa agatcttcct tcacaccaga
     1501 gagaaatgac ccagttattc tttgaatcat ttttcttagg tatggcaaac ttatcggaga
     1561 actattctga gttcgtccaa accagagtta tcacagaaaa ctaacacgga ggaaaacatt
     1621 atgttaaaaa tgactcttaa caacttgcaa cttttcgccc acaaaaaagg tggaggttct
     1681 acatcaaacg gacgtgattc acaagcaaaa cgtcttggag ctaaagcagc tgacggacaa
     1741 actgtaacag gtggatcaat cctttaccgt caacgtggta cacacatcta tccaggtgta
     1801 aacgttggtc gtggtggaga cgatactttg ttcgctaaag ttgaaggcgt agtacgcttt
     1861 gaacgtaaag gacgcgataa aaaacaagtt tctgtttacc caatcgctaa ataaaaaggt
     1921 ccattgaacc ttttatcccg aaccttgaaa tgtaaaggtg aggaagctag aaacagctta
     1981 aaataaggct ttccgagttt tcggagagcc tgtttttttg ttttggtacc catacttttt
     2041 aatatgtata gtggattgaa tctggaatag aacactgtta aaaattgata tgagtttcct
     2101 actcgatttc ttcagatttt atttcaattg actataagaa ctgctatctg gtttcaaata
     2161 ttggcttgtc gtcccttcac ttgtctgaat ggtttgagcc gttccttctg ataagggaaa
     2221 agatattctt tagctgaaac tgtctgagaa tccaagctaa cagatggaga gaaaaatagc
     2281 ccagtctgaa gcacactaga tgggagttgt tggaaagcag tcatctagtt tttctttgct
     2341 gttttggctt ttttctttgt catcagggaa agtgacttgc ttcaaatcag ggagtttagg
     2401 aaattcttca aacatcttgc ccaagttgtc tcattttgta aattttacag ccataggtgt
     2461 acctcgattc taaattctac cttttcggca ccaattagta atttaaagtt ctcaggagtt
     2521 agttgcattg ctttttcata cataagcata gtatgacact ttatggttac cgaacaagtc
     2581 taatcactcc ttgcaaaatt ttgaagatgt cctacaagtt tttgagaaga atattgcaaa
     2641 gttcatagtt aagcaacgat agaataaagt gctttttgaa aacaggtaca cttcatgtga
     2701 aaaaaacaac atttcagatt ttctgttcca gaaatagcta tcgctatgat ataattattt
     2761 tatgattatt actattccta taaaaaacca aaaagatatt ggcacaccat ctgattcagt
     2821 cgttgttctc ggctattttg atggcataca taaggggcat caagaattat ttcgtgttgc
     2881 caacaaggct gcgagaaagg atttattacc tatcgtcgtt atgaccttta atgaatctcc
     2941 aaagatcgct ttagagcctt atcatccaga tttgtttttg catattttga accctgctga
     3001 acgtgaaaga aaattaaagc gcgaaggtgt agaagaatta tatctccttg attttagtag
     3061 tcaattcgct agtctcactg cacaagaatt ttttgcaact tatatcaagg ctatgaatgc
     3121 caaaattatt gttgcaggtt ttgattatac atttggttct gacaaaaaaa cagcagaaga
     3181 tttaaaggat tactttgatg gagaagttat cattgttcca cctgtagaag atgagaaagg
     3241 aaagattagt tcaactcgta tccgtcaagc tattttagat ggaaatgtga aagaagcagg
     3301 aaaacttttg ggggcaccgc ttccatcaag aggtatggtg gttcatggta atgctcgtgg
     3361 tcgtacaatt ggttatccga cagcgaattt agtgctttta gaccgtactt atatgccagc
     3421 agatggcgtt tatgtcgttg atgttgagat tcaaagacag aagtatcgtg ctatggctag
     3481 tgtcgggaaa aatgtgacct ttgatggaga agaagcacgt tttgaagtca atatttttga
     3541 ttttaatcaa gatatttatg gggaaaccgt catggtttat tggcttgatc gcattcgtga
     3601 tatgaccaaa tttgactcag ttgaccaatt agtggatcag ttaaaggctg atgaagaagt
     3661 aactcggaat tggtcttaag agcttgagta aataaaataa aaaagaggtt gtctgtaacc
     3721 caaaagatag atgatttagt ctaacttttg aggtcacgac attacctctt tttattcttt
     3781 ttcaaaggtg aagccttctc ctaggatttc atgggcttct gtaatagtta taaaggcttg
     3841 aggatcgatt cgatgaatca tttccttcgt tttcacaatt tcatttcttc cgacaataca
     3901 gtagatgatt ttcaaatttt ctttactata gtagccttga ccagaaataa aagtaacacc
     3961 tcttccgagg tcatcattaa tcgccttagc aagttggtca ggacgttttg tgataatcat
     4021 aaagcctttg ccggcatatc ctccttcacc aatcaaatca ataacacgag aaacaataaa
     4081 atcaaacaaa agcgtgtagg aaaccaatct caaatccttg aagattagga gaatcaacat
     4141 gagaatacaa aaatctaaga taaagagcag ttttcctatg gatatatgag tgtatttgtt
     4201 gagaatacga gctagaatat cagttccgcc agttgtacct ccagcattaa aaataattcc
     4261 aaggccaatt cccaatagga ttcccgctat aagggctgtg attagtaaat caccttgaag
     4321 atcaatatga aggggaatat gctcaaaaaa agctaaccag ccggacaaag ctaaggttcc
     4381 tagtaaacta gaatagaggg atttggctcc aaagatcttc caagctagga tgaaaagggg
     4441 aatattaatc agcaggttca tgagggaaac agggatttta aaaagataaa atgtgatgag
     4501 ggtaatacct gtcgcccctc cttcaaagag atgatgggga actacaaaat aagtcagtcc
     4561 aaaagcataa atagcagcac ctagtaaaat ggtaaaaatg gggtaaattt ttttaatcat
     4621 aggacacctc ttttcttata agttgattat atcaaatttt acggaaa
//
LOCUS       DAVLMQ010000094         4595 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000094 DAVLMQ010000000
VERSION     DAVLMQ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4595
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.095"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            81..173
                     /locus_tag="VXF95_002082"
                     /pseudo
     CDS             81..173
                     /locus_tag="VXF95_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(786..983)
                     /locus_tag="VXF95_002083"
     CDS             complement(786..983)
                     /locus_tag="VXF95_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082563.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEASNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
     gene            complement(968..1186)
                     /locus_tag="VXF95_002084"
     CDS             complement(968..1186)
                     /locus_tag="VXF95_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HEV1082564.1"
                     /translation="MKDLPEWFGIPESTQTYIEGTTTLQVWTAYQESDLTGFVSLSYS
                     SEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            complement(1284..2069)
                     /locus_tag="VXF95_002085"
     CDS             complement(1284..2069)
                     /locus_tag="VXF95_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HEV1082565.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            complement(2071..2889)
                     /locus_tag="VXF95_002086"
     CDS             complement(2071..2889)
                     /locus_tag="VXF95_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HEV1082566.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            complement(2891..3883)
                     /locus_tag="VXF95_002087"
     CDS             complement(2891..3883)
                     /locus_tag="VXF95_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HEV1082567.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQDNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPDSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINQEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
BASE COUNT         1545 a          961 c          809 g         1280 t
ORIGIN      
        1 ataaaaacag tatatcattt aaaaaaattt aattcaagaa aaattaacat gcattaattt
       61 attttttagc acacgttaaa aagtaagatt agtactcaat gaaaatcaaa gagcaaacta
      121 ggaaactagc cgcaggttgc tcaaaacact gttttgaggt tgtagatgga actgacgtag
      181 tcagctcaaa acactgtttt gaggttgtgg atggaactga cgtagtcagc tcaaaacact
      241 gttttgaggt tgtagatgga actgacgtag tcagctcaaa acactgtttt gaggttgtag
      301 atggaactga cgtagtcagc tcaaaacact gttttgaggt tgtggataga actgacgaag
      361 tcagctcaaa acactgtttt gaggttgtgg atagaactga cgaagtcagt aaccatacgc
      421 acggcaaggc ggcgttgacg tggtttgaag agattttcta agagtataag tccaaaactt
      481 tcgttaaccg ggatacatta taagcacatt cataccatca aaaatagtag caataaactt
      541 gaacaactac cggaaacacg aaaacaggca taattgatga aatatcagcg ctattaaaca
      601 atataaataa ccgctaagaa taaggcttaa cggttatctt ctacctatct attttttcaa
      661 ctcctcagtc gtttatctac ctataaccta ggctttacga gtgccttgct ctaccaactg
      721 agctaaatcg gcgattacac ttacagtata gcactctgag aataaaaaat agatgtcaag
      781 taatattatt caagcttttt aatcaaaatc tgacaaggat tttgcggatt ccatagttga
      841 ggaaaaatct ctaacttttt aaagccaaga cctcgataaa agtcatttgt tcgatcataa
      901 tctttattag aagcttctgc cactgttttg acctgcagat aaccaacttt tttacgagct
      961 tcactctcta aagtagcaag caattggctc ccaatttttc taccttgata agctttttta
     1021 cgccgagaca atcaatctct gcacaatctt cactcgaata ggataagctt acaaatccag
     1081 tcaaatcact ctcctgatag gcggtccaaa cttgcagtgt cgtggttcct tctatatagg
     1141 tttgtgtgct ttctgggatt ccaaaccatt ctggcaaatc cttcaaaatc tcagcgacaa
     1201 ctgccttttt tgattttcat ccttgacttc ttcaattaca aacatcataa gttcctttct
     1261 tgattttagt cttactttag cttttacgaa cccgcacttt cgtaggaatc taagccctta
     1321 tcccaaagtt taagggaaat aacaaagaaa accagagaaa tcaacatcaa acctcctacg
     1381 ttaaagaaca catccttttc ctgtaagaaa tagctagctg gatagtaggc tgtaaaggcg
     1441 aaaggcacga taaagctaat caaccaacga agaagagaat tgtaaataga aatcggatac
     1501 ttagcaaagt cattgaacat atagaagatg taaatcatgg cgcctgactg cttagtccaa
     1561 aaggcgatac tggctgttgc gattttaaga gaagtataaa tcaaggtcgc aaaaggaata
     1621 caaactagga aaagcagaaa ttttggaaga gtccaaacaa tgctggtcac tgttgttccc
     1681 aataaaatac caccgactaa gagttcaccc aaggcatcaa tctgaaaggt ttcaactagg
     1741 atgtgaaaga gaggattgat gggacgagtc agatacttgt caaactctcc ttttcggact
     1801 aggcgttgcc ctagtgccca gagattgtca aaaaagagat ggtccattcc cttgggaatc
     1861 aaggaaaatc cataaatgaa agctatctct tgaaaggtcc aaccttctag gaatggaata
     1921 tgttgaaaga tgacattgag aaacaagaga ttcaagcctt gagccagaaa gactcccaag
     1981 acaccaacca caaaatccac cttatattcc atgatttgtt tgatgtattg tctgataaaa
     2041 atcagatgca ttcgttgata ttttttcata ctaacctcct tgaatggtga taaaggactg
     2101 gacccgtttc caaatcaact gagacaatcc caccatcact aagagccaga agaactgcaa
     2161 aaggagtgcc tgaagaatct gactggcatc gtattttcca acaatgatca taactggagt
     2221 ataaatcaag gatgaaaaag gcaaaaagga aagaatatct gaaacaacct ttggaaagaa
     2281 tgccaaggga atcaaacttc ccgacataaa agccactatg gaagtcttaa gtaggttgga
     2341 accccaaaga tttttaaaca caaaggctga aaatccaaag caaatattaa agaaaaagtt
     2401 aatcagatag gcgagcgtta agctaaaaag ataaaggaca gttaatccta gcacctctac
     2461 aataccttga cccgatatga ttttcatcaa gacaatgaca cttaaaaatg gaaggccaac
     2521 gctgataaaa atcaaccact tggaaccaag ctcggtgaaa agataggagg ccgcaaaatg
     2581 cactggtcgc aacaaacgca tgataatgga gccatccttg acctcctccc caatcataaa
     2641 ggacgaatcg gatctagtca gaagattggt cacaaaactc atgatgatgt agagggtgat
     2701 atccgccata ctgaagccct gaatcaaaga ctcttgcgaa gaatcaaaga cagccttcca
     2761 gagataaaag gccacaaaag cccccatgac atcgccaatc cgatagagaa taaagttgac
     2821 tcggtaagta atcaactcct gaacccctgc attgataaag ggtttataac gtctccacaa
     2881 tttgatcatc ctagagctcc tttcggtaga agcgacggat aatatcctca atatccgtat
     2941 ccaccatctt caaatcgcgg atttcaaaat cagacagggt ttgcttgata atgtcagctg
     3001 actggtagcg agaactatca aattcaatgt tgaggctgtt tccttgtcta tcaatggtca
     3061 tatcagacag accttcatag tgagagacga gatgactttg acctggtagc agttcaaaag
     3121 agagagtctt catcttacca aaggtctcct tgagttggct caccgttcca tcaaaaatct
     3181 cttgcccctt gtcaatcatg aaaatccgat cacaaagttg ctcaatatca ctcaaatcgt
     3241 gagtggtcaa aagaatggta gtttcttcct cttgattgat ctgagtaatt gcccgacgaa
     3301 tattatcctt aaccgaaacg tccaaaccaa tggtcggctc atctaaaaaa agaaccttgg
     3361 gattgtggag caaggaggcc gcaatatccg cccgcatccg ttgtcccagt gaaagagtcc
     3421 gcacgggatc cttgataaag tccttcaaat ccaagacttc attcaaaaag tccatacgct
     3481 tatgaaagag cgagtctggc acatcataaa tctcttttaa gacagtgtag gtctcttgca
     3541 gagccaaatc ccaccatagc tgggtgcgtt gtccaaagac tacgccaata tctttgacat
     3601 aatcttgccg attgtcctgg ggaatcttgc cgttaatccg acaaaaacca gatgttggtt
     3661 tcaaaattcc tgtcagcatt ttaatggttg tcgacttccc agcaccattt gccccgataa
     3721 atcctaaaat ctgccctttt ggaacctcaa aggtcaaatc cttgaccgct tcaaaggtct
     3781 gcttttcagg atgaataaag gagcgcaaag cccccttcaa gcccggttcc ttaacagtct
     3841 tcacaaaatt tttctgaaga tgttccactt ctatcattgc catatctatc tccctatcgt
     3901 aaggaatagc aacattgtgt ttttaactac aaatattcta aatccttgct ttctacacct
     3961 tctacatttt attactacaa aaggctttat accaacctat tatagtccaa taaaaaacga
     4021 aatgcaagag tttgcctatg gattgtgaaa ttaggatttc tctcataaaa taatactttt
     4081 aatcaaaaat tctgtttaat agtttaaatt accaacctac tcatcttctc accagagggc
     4141 ggtattaact ttgatcataa aatcggatac tccctctatc cagaaaatat gctcagaatg
     4201 attgtctcta aacaatacct gctcttttac ctcattcatg aaaaagaagt ccataccctg
     4261 agaattatca actcacgcat cgactaccta aaccaactcg accacctctt tcgtacatgt
     4321 aggaaactat tttcctcaca aataatctca ttataaaatc caataaattt ttttagctca
     4381 cttgaatatt ttctttgtat cgttttatca gcttcaatct gatctagact tgttaccttg
     4441 gaacgacttg aaataacctt tataaaataa cacttaaggc tttcatcatc tcgtataaat
     4501 ttttcaatag tgatataaaa agctttcata ttctgtttgt aatcagatat caattgatta
     4561 attttatcat tctgatgaag attcgatacc ataat
//
LOCUS       DAVLMQ010000095         4338 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000095 DAVLMQ010000000
VERSION     DAVLMQ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4338
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.096"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            105..584
                     /locus_tag="VXF95_002088"
     CDS             105..584
                     /locus_tag="VXF95_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HEV1082568.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
     gene            678..749
                     /locus_tag="VXF95_002089"
     tRNA            678..749
                     /locus_tag="VXF95_002089"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:711..713,aa:Glu,seq:ttc)
     gene            1001..2546
                     /locus_tag="VXF95_002090"
     rRNA            1001..2546
                     /locus_tag="VXF95_002090"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            2598..2670
                     /locus_tag="VXF95_002091"
     tRNA            2598..2670
                     /locus_tag="VXF95_002091"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2631..2633,aa:Ala,seq:tgc)
     gene            2795..>4338
                     /locus_tag="VXF95_002092"
     rRNA            2795..>4338
                     /locus_tag="VXF95_002092"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1308 a          814 c         1228 g          988 t
ORIGIN      
        1 ccctctcttt tttgtgcagt ttaggagcta aagggaacag aatggagaaa atggaacaaa
       61 tgtgttttct aatctgttag actgtatcta gaaaggggaa aattatgatt aaagaattgt
      121 atgaagaagt ccaagggact gtttataagt gtagaaatga atattacctt catttatggg
      181 aattgtcgga ttgggaccaa gaaggcatgc tctgcttaca tgaattgatt agtagagaag
      241 aaggactggt agacgatatt ccacgtttaa ggaaatattt caaaaccaag tttcgaaatc
      301 gaattttaga ctatatccgt aagcaggaaa gtcagaagcg tagatacgat aaagaaccct
      361 atgaagaagt gggtgagatc agtcatcgta taagtgaggg gggtctctgg ctagatgatt
      421 attatctctt tcatgaaaca ctaagagatt atagaaacaa acaaagtaaa gagaaacaag
      481 aagaactaga acgcgtctta agcaatgaac gatttcgagg gcgtcaaaga gtattaagag
      541 acttacgcat tgtgtttaag gagtttacta tccgtaccca ctagtaagtc atgcaaaaaa
      601 aatgaaaaaa attagaaaaa gtagttgaca aagtttgaaa agactgtata atagtaagag
      661 ttgaaaataa caactcaggt ccgttggtca aggggttaag acaccgcctt ttcacggcgg
      721 taacacgggt tcgaatcccg tacggactat ggtatgttgc ggttggaaca cttgatgaaa
      781 aaaagtttaa aaaagcttaa aaatcttcaa aaaagtgttg acaagtgaaa gtggctgtga
      841 tatactaata tagttgtcgc ttgagagaag caagtgacaa agacctttga aaactgaaca
      901 agacgaacca atgtgcaggg cgctacaaca taagttgtag tactgaacaa tgaaaaaaca
      961 ataaatctgt cagtgacaga aatgagtgag aactcaaact tttaatgaga gtttgatcct
     1021 ggctcaggac gaacgctggc ggcgtgccta atacatgcaa gtagaacgct gaaggaggag
     1081 cttgcttctc tggatgagtt gcgaacgggt gagtaacgcg taggtaacct gcctggtagc
     1141 gggggataac tattggaaac gatagctaat accgcataag agtggatgtt gcatgacatt
     1201 tgcttaaaag gtgcacttgc atcactacca gatggacctg cgttgtatta gctagttggt
     1261 ggggtaacgg ctcaccaagg cgacgataca tagccgacct gagagggtga tcggccacac
     1321 tgggactgag acacggccca gactcctacg ggaggcagca gtagggaatc ttcggcaatg
     1381 gacggaagtc tgaccgagca acgccgcgtg agtgaagaag gttttcggat cgtaaagctc
     1441 tgttgtaaga gaagaacgag tgtgagagtg gaaagttcac actgtgacgg tatcttacca
     1501 gaaagggacg gctaactacg tgccagcagc cgcggtaata cgtaggtccc gagcgttgtc
     1561 cggatttatt gggcgtaaag cgagcgcagg cggttagata agtctgaagt taaaggctgt
     1621 ggcttaacca tagtaggctt tggaaactgt ttaacttgag tgcaagaggg gagagtggaa
     1681 ttccatgtgt agcggtgaaa tgcgtagata tatggaggaa caccggtggc gaaagcggct
     1741 ctctggcttg taactgacgc tgaggctcga aagcgtgggg agcaaacagg attagatacc
     1801 ctggtagtcc acgctgtaaa cgatgagtgc taggtgttag accctttccg gggtttagtg
     1861 ccgtagctaa cgcattaagc actccgcctg gggagtacga ccgcaaggtt gaaactcaaa
     1921 ggaattgacg ggggcccgca caagcggtgg agcatgtggt ttaattcgaa gcaacgcgaa
     1981 gaaccttacc aggtcttgac atccctctga ccgctctaga gatagagctt tccttcggga
     2041 cagaggtgac aggtggtgca tggttgtcgt cagctcgtgt cgtgagatgt tgggttaagt
     2101 cccgcaacga gcgcaacccc tattgttagt tgccatcatt tagttgggca ctctagcgag
     2161 actgccggta ataaaccgga ggaaggtggg gatgacgtca aatcatcatg ccccttatga
     2221 cctgggctac acacgtgcta caatggctgg tacaacgagt cgcaagccgg tgacggcaag
     2281 ctaatctctt aaagccagtc tcagttcgga ttgtaggctg caactcgcct acatgaagtc
     2341 ggaatcgcta gtaatcgcgg atcagcacgc cgcggtgaat acgttcccgg gccttgtaca
     2401 caccgcccgt cacaccacga gagtttgtaa cacccgaagt cggtgaggta accgtaagga
     2461 gccagccgcc taaggtggga tagatgattg gggtgaagtc gtaacaaggt agccgtatcg
     2521 gaaggtgcgg ctggatcacc tcctttctaa ggataaggaa ctgcgcattg gtcttgttta
     2581 gtcttgagag gtcttgtggg gccttagctc agctgggaga gcgcctgctt tgcacgcagg
     2641 aggtcagcgg ttcgatcccg ctaggctcca ttggtgagag atcaccaagt aatgcacatt
     2701 gaaaattgaa tatctatatc aaatagtaac aagaaaataa accgaaaacg ctgtagtatt
     2761 aataagagtt tatgactgaa aggtcagaaa ataaggttaa gttaataagg gcgcacggtg
     2821 gatgccttgg cactaggagc cgacgaagga cgtgacaaac gacgatatgc cttgggtagc
     2881 tgtaagtaag cgatgatcca gggatttccg aatgggggaa cccaacaggt aatacctgtt
     2941 acccacatct gttaaggatg tgaggaggaa gacgcagtga actgaaacat ctaagtagct
     3001 gcaggaagag aaagcaaaag cgattgcctt agtagcggcg agcgaaacgg cagaagggca
     3061 aaccgaagag tttactcttc ggggttgtag gactgcaatg tggactcaaa gattatagaa
     3121 gaatgatttg ggaagatcag ccaaagagag taatagcctc gtatttaaaa tagtctttgt
     3181 acctagcagt atcctgagta cggcgggaca cgtgaaatcc cgtcggaatc tgggaggacc
     3241 atctcccaac cctaaatact ccctagtgac cgatagtgaa ccagtaccgt gagggaaagg
     3301 tgaaaagcac cccgggaggg gagtgaaata gaacctgaaa ccgtgtgcct acaacaagtt
     3361 cgagcccgtt aatgggtgag agcgtgcctt ttgtagaatg aaccggcgag ttacgttatg
     3421 atgcgaggtt aagttgaaga gacggagccg tagggaaacc gagtctgaat agggcgcctt
     3481 agtatcatga cgtagacccg aaaccatgtg acctacccat gagcaggttg aaggtgcggt
     3541 aagacgcact ggaggaccga accagggcac gttgaaaagt gcttggatga cttgtgggta
     3601 gcggagaaat tccaaacgaa cttggagata gctggttctc tccgaaatag ctttagggct
     3661 agcgtcgaca ttagagattc ttggaggtag agcactgttt gggtgagggg tccatcccgg
     3721 attaccaatc tcagataaac tccgaatgcc aatgaattat ggtcggcagt cagactgcga
     3781 gtgctaagat ccgtagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
     3841 attgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttag cttagaagca
     3901 gctattcatt caaagagtgc gtaatagctc actagtcgag tgaccctgcg ccgaaaatgt
     3961 accggggcta aaacaattta ccgaagctgt ggataccttt ataggtatgg taggagagcg
     4021 ttctatgtgt gatgaaggta taccgtgagg agtgctggaa cgcatagaag tgagaatgcc
     4081 ggtatgagta gcgaaagaca ggtgagaatc ctgtccaccg taagactaag gtttccaggg
     4141 gaaggctcgt ccgccctggg ttagtcggga cctaaggaga gaccgaaagg tgtatccgat
     4201 ggacaacagg ttgatattcc tgtactagag tatgtagtga tggagggacg cagtaggcta
     4261 actaaagcag acgattggaa gagtctgtct aagcagtgag gtgtgatatg agtcaaatgc
     4321 ttatatctgt aacattga
//
LOCUS       DAVLMQ010000096         4095 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000096 DAVLMQ010000000
VERSION     DAVLMQ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.097"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            32..847
                     /locus_tag="VXF95_002093"
     CDS             32..847
                     /locus_tag="VXF95_002093"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HEV1082569.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIEAYREVGIQAHGYVCDVTDEDGIQAMVKQIEQEVGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            866..1507
                     /locus_tag="VXF95_002094"
     CDS             866..1507
                     /locus_tag="VXF95_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HEV1082570.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            1538..2539
                     /locus_tag="VXF95_002095"
     CDS             1538..2539
                     /locus_tag="VXF95_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HEV1082571.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITIAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISALEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKETYGFKAIFHTLRSSDEQDKNVYQAYALEERFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            2549..3178
                     /locus_tag="VXF95_002096"
     CDS             2549..3178
                     /locus_tag="VXF95_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HEV1082572.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(3557..3942)
                     /gene="tnpA"
                     /locus_tag="VXF95_002097"
                     /pseudo
     CDS             complement(3557..3942)
                     /gene="tnpA"
                     /locus_tag="VXF95_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT         1215 a          888 c          814 g         1178 t
ORIGIN      
        1 aagtcttaac aaatttgaaa ggaagtatca aatgacaaat acatcattct caattgagca
       61 gttttcttta aaaggaaaaa ttgctctcat caccggcgct tcttatggaa ttggatttgc
      121 tattgccaaa tcctacgctg aagccggcgc tactattgtc tttaacgata tcaatcaaga
      181 tctggtcaat aaagggattg aagcttatcg tgaagttggc atccaagccc atggatatgt
      241 ctgtgacgtg acagacgagg acggtatcca agccatggtc aagcaaatcg aacaagaggt
      301 tggtgtcatt gacatcctcg ttaataacgc tggtattatc cgccgagttc caatgtgcga
      361 aatgagcgcc gctgatttcc gtaaggtcat cgatattgac ttaaacgcac catttatcgt
      421 ttcaaaggca gttattcctt ctatgataaa gaaagggcat ggaaagatta tcaatatttg
      481 ttcgatgatg agcgaactgg gacgtgaaac agttagcgct tatgctgctg ctaaaggggg
      541 cttgaaaatg ttgacccgca acattgcgtc tgaatacggt ggagccaata tccaatgtaa
      601 cggaattgga ccaggttata ttgccactcc tcaaacagca cctcttcgtg agttgcaaga
      661 agatggttct cgccacccat ttgaccagtt catcattgca aaaacacctg ctgcacgttg
      721 gggaaatcct gaagatttga tgggccctgc tgtctttctc gctagtgatg ccagcaattt
      781 tgtcaatggc cacatcctat atgtagatgg cggtatctta gcctacatcg gaaaacaacc
      841 tgagtaaaaa tagaaagaag atcttatgaa aatcgcatta atcaatgaaa atagtcaagc
      901 tagcaagaat cacattattt acgatagtct aaaagaagcg acagataaaa aagactacca
      961 attatttaac tatggtatgc gtggagaaga aggagaaagt caattaactt atgtgcagaa
     1021 cggactaatg gctgccatcc ttttaaatac aaaggcagtt gactttgttg ttaccggctg
     1081 tggtacgggt gtaggggcta tgcttgcttt aaacagcttc cctggtgttg tctgtggtct
     1141 agcagtggac ccaactgacg cttaccttta ttctcaaatc aatggtggta acgccttgtc
     1201 tatcccttat gccaaaggat ttggctgggg ggcagaactg accctcaaat tgatgtttga
     1261 acgcttattt gctgaagaaa tgggcggtgg ctacccaaga gaacgtgtaa tccctgaaca
     1321 acgcaacgct cgtatcttaa acgaggtgaa acaaatcacc cacaatgatt tgatgaccat
     1381 ccttaaaaca atcgaccaag acttcctcaa agacaccatc tctggcaaat acttccaaga
     1441 atacttcttt gaaaactgcc aagatgatga agtcgctgct tatttgaaag aagtattagc
     1501 caagtaaagc tattctaaac cagaaaggaa ctaatggatg acgaaaatat tactgtttgg
     1561 cgaaccatta attcgaatct caccattaga tgccaccagt atcggcgatc atgttgccag
     1621 ttcgacttat tttggcggat cagaaattaa catcgcttgt aatttgcaag ccctgggtat
     1681 ctcaacgaaa gtctttaccg cactccctgc caacgagatt ggagatcgtt ttctcacatt
     1741 cttgaaacag caccaaatcg ataccagttc aatctgtcgg cttggcgatc gaatcggcct
     1801 ctactatttg gagaacggct ttggttgtcg tcaaagtgaa gttttctacg atcgtaagca
     1861 tacgagtatc agccagattc ggccaaacat gctagatatg gattctctct ttcaggggat
     1921 tagccatttt cattttagtg gaatcaccat agctatcggt caagaggtcc gtgcgatcct
     1981 tctcctactc ttggaagaag ccaagcgccg aggaattgtc gtttcaatgg atctcaatct
     2041 gagaacaaag atgatttcag ccctagaagc caagtatgaa ttttctaagt ttgcacgttt
     2101 tactgactat tgcttcggta ttgatcctct catgattgat gaccaaaatc tagagatgtt
     2161 tccaagagac agtgctagcc tagaagaggt ggaaaatcgc atgcgacttt taaaagaaac
     2221 ctatggtttc aaggctattt tccataccct ccgatctagt gatgagcaag acaaaaatgt
     2281 ctatcaagcc tatgctctgg aagaacgatt tgaagagtct gtccaactaa aaactgcagt
     2341 ctatcaacga attggtagcg gggatgcctt tatatctggt gccctttacc aactactcca
     2401 tcattcctcc ctaaaaacta ccattgactt tgcagttgcg agcgcaactc tcaaatgcac
     2461 tcttccagga gaccatctct ccacttccgc aactagtatt gaaaatttac tggcaaatgc
     2521 acaagatatc attcgttagg agaattacat gaccaaatca gatacgatta ttgaactaaa
     2581 aaaacagaaa attgtcgctg tcattcgagg aaatacaaag gaagaaggac tacaagcctc
     2641 gattgcttgt atcaagggcg gtatcaaagc tattgaaatc gcctatacca atcagtatgc
     2701 aggacaaatc atcaaggaac ttgtagactt gtatcaggac gatcagagtg tttgtatcgg
     2761 tgcaggtact gtgcttgatg ccgtaactgc tagagatgcc attctagctg gagcaaatta
     2821 cgttgtttct ccatctttcc atgctgaaac tgcgaaaatg tgcaatctct acagcacacc
     2881 gtacattcca ggctgtatta ccctcacaga gatcacgact gcacttgaag ccggtagtga
     2941 aatcatcaaa ctcttcccag gtagtactct cagtccagca tatatctctg cagtcaaggc
     3001 accgatccca caagtttccg taatggtaac cggaggagtc ggcctaaaca acatccctca
     3061 atggttcgct gctggtgcag atgccgttgg aattggtggc gaactcaata aactcgcttc
     3121 ccaaggcaac tttgaccgca tcagcgagat tgcccaacag tatattacac tcagataaaa
     3181 tcataactac ccgtctaacg ggtggtttat ctcagagcta taagcccaaa tcatcagcca
     3241 gcgcctaaag acgctggctt tcacgttgtt caagccttat tgctcttgac tcgtcacttg
     3301 cctctttaag agactttggt attacttacc actatcccta aagggatcct catattcttt
     3361 tacactcaat ttatctagtg ctatagtaga ttgaaactgg aatagtatac ctctacttct
     3421 aaaacattgt taaaaatcga tttgactgtc ctgatcgatt tcgtcctgtt cttatttcat
     3481 tttactatat atcatacttt actagttctc aaattttcat actcgtgaag aaatcatcca
     3541 ctcgataatt tctttaatct tgactatatt tcttaattgt ggcttcatta agccctactg
     3601 gacttacata ataaccttcc gcccagaaat tccgattccc aaacttgtac ttgagattgg
     3661 cgtgtttgtc aaacatcatg agtgcacttt tgccttttaa ataccccata aaacttgaaa
     3721 cacttagcct cgacggaata ctgactaaca tgtgtacatg gtctggcatt aagtgaccct
     3781 cgatcatttc aacaccttta taactacaca agcgatgaaa tatttcgcct aaactacttc
     3841 tatattgatt atagatgact tttcgtctat acttaggggt gaacacaata tgatagaaca
     3901 catccacttt gtgtatgata aactatgagt cttttgtgcc atattttttc tcctttcgct
     3961 ttacaattgg attgaatacc tttattgtat cgcgtttgga gtttttttgg tataaccttc
     4021 gacgcgcacc tcacggagcg agacggactt atatagtgga gtgaaatagg atacgaacaa
     4081 attgattagg aaaat
//
LOCUS       DAVLMQ010000097         4086 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000097 DAVLMQ010000000
VERSION     DAVLMQ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4086)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4086)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4086
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.098"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(304..3201)
                     /gene="nanA"
                     /locus_tag="VXF95_002098"
     CDS             complement(304..3201)
                     /gene="nanA"
                     /locus_tag="VXF95_002098"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HEV1082573.1"
                     /translation="MNRSVQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGESSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDAKAPAFYNLFSVSS
                     ATKKDEYFTMAVYNNTATLEGRGSDGKQFYNNYNDAPLKVKPGQWNSVTFTVEKPTAE
                     LPNGRVRLYVNGVLSRTSLKSGNFIKDMPDVTHVQIGATKRANNTVWGSNLQIRNLTV
                     YNRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKEIDGKTYQILY
                     REGEKEAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLNGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NKRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTATFLTQYDSKTLLFAVDKEDIGQEIIGIAKG
                     SIESMHNLPVNLAGARVPGGVNGSKAAVHEVPEFTGGVNGTEPAVHEIAEYKGSDSLV
                     TLTTKEDYTYKAPLAQQALPETGNKESDLLASLGLTAFFLGLFTLGKKREQ"
     gene            complement(3489..3716)
                     /locus_tag="VXF95_002099"
     CDS             complement(3489..3716)
                     /locus_tag="VXF95_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082574.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
BASE COUNT         1133 a          897 c          664 g         1392 t
ORIGIN      
        1 aagataagaa aacaagaaag tcaattttag aagaagagaa ggttaatagt cacataatat
       61 attgaatcta taacagtaca ccttgactgc taaaattttt ctataaatta atttgacttt
      121 cctgatagag ttgttcacat cttatttcaa tctactatat tttatagaac agactactct
      181 gaaagtagtt tcagacctct tatgatttcg tatcagcctg aatgtcatca aaaaaagata
      241 gcaggcttaa aaacctgcta tctccttcta tttttacaaa atcaaatgtt tagaattctt
      301 ctcttattgt tctctctttt tccctagcgt aaacagacca aggaagaaag ctgttagtcc
      361 tagtgaagct aggaggtcac tctccttgtt tcctgtttca ggaagtgcct gctgagcaag
      421 aggagctttg taagtataat cttcttttgt agtaagagtt acaagcgaat cagatccctt
      481 atactctgcg atttcatgaa cagctggctc tgtaccatta actccccctg taaattctgg
      541 aacttcatgc accgctgctt tgctaccatt tactccgcca ggaactctgg cacctgctag
      601 atttacagga agattatgca tactttcgat gcttccttta gctataccaa taatttcctg
      661 tccgatatct tccttatcta ctgcaaacaa caaggtcttg ctatcatact gggttaggaa
      721 agtcgctgtt ttaccatttg ccaattgaag tgttggagcc ttgttgacca atacttctga
      781 gtcgaactcc aagccaataa ctcctttgcc catctctcct ttgcccatct ctctagttcg
      841 cttcactttc gcttcggtag gagaaatcag atttttgctc aaaaattccc aattaaattt
      901 tctaaatgat agggtatagg cattttgtcc tttttcagta tgttcataca agatgccata
      961 ctccccattt cctaattctt ggagcgaatt ataggcaaac tctccttttt gaattggatt
     1021 gtgtttgagc caagtcaact caccattttc ttcgacacgt gccaagtgga ccatcccatt
     1081 ttcacgtttc ggtccacctg cattactgag gatgatgtat tcttttcctt cgtgcatcgt
     1141 atggatagca gacatttgaa catagacatc tttaacctgt ggataacgtt tgatatcctt
     1201 ctcccaagtc actcctccgt ctttacttgt agcaacctga agatctccag tcaaaccacg
     1261 cataaagagt ttaacatctc cattgtttag ttgtaccacc gttgattctg tattttgcgc
     1321 acgtttattg ttcatcgtag aagagtggat cttttgaccg tctacctgac ggttatcgtt
     1381 gaccgcttct ccagcatgcc aagtttttcc atgatcatct gaatagatga cacgagaaga
     1441 ttgcgagcca tttaagtgag atacattatt agtcgtataa accggtatca aaatccgtcc
     1501 cttgtgaggc ccattccgaa gtacaattcc tgttccagga cctacaccca agaatttcat
     1561 ccaatcggct ttgaccatcg gagtaatatc ttgaggcgct gaccatgtct tcccgtcgtc
     1621 atcactgtag gacatccata gatagctatc cttggcaatt ctaaatggag aagttttgtt
     1681 tgttgtgaag tagatatttc ctagtaattg gtcacccttg tatagatcac ccttgtcgct
     1741 ataggctggt ttaacaggat ctacaacaac gcgatagtct gtcgccttac catctggtgt
     1801 atagacagta ccattttctc gaatggtata agcttccttt tctccctcac gatagaggat
     1861 ttgataggtt tttccatcga tttctttgta ggcttcttct ttttgtgaag acattccaaa
     1921 gattcccttc ccttctggga acatgtcata gatagaaaag attcgtttgg tttcaggatc
     1981 ttgaaccaac accatatcga tattcactgg tgaaccgatc gatgggtcag aagcttttgg
     2041 attgtcacgt aagttggtaa tggttactcg gtcaccccaa gttttaccat tatcttcact
     2101 acgtctgatg accataccga tatcacccca gtcactcgaa tggagacggc gttcatctgc
     2161 acctgcgatc aaagttcctt tatctgtctt gagaagtgct ggaatacgat aactcttgat
     2221 tccatcttta tttggtttgt tgttcattcc cccttcaaag acgtcttctt tctctgagat
     2281 tttcgcacct tctggaagtt tcttctccaa atcacctctt tcaaatagtt ggcttctcgt
     2341 ctgaacttct tctgggctta aggcacgatt atacacagtg agattccgaa tctgtagatt
     2401 tgacccccaa accgtattgt tggcacgctt ggttgctccg atttgcacat gcgttacatc
     2461 tggcatatct ttaatgaaat tgccagattt cagacttgtt cgagataaaa caccattaac
     2521 atacaggcga actcgaccat ttggcaattc tgctgttggt ttttcaactg tgaaagtcac
     2581 agaattccac tgacctggtt taacttttaa gggtgcatcg ttgtaattat tgtaaaactg
     2641 tttcccatcc gaaccacgcc cctctagagt agcagtatta ttgtaaactg ccatagtgaa
     2701 gtactcatct tttttagtag cacttgacac agaaaagaga ttatagaatg ctggagcctt
     2761 ggcatctggc ttaaactcca tgtgaactgt tgcgttttca agtttcttta gtttatctag
     2821 ttcacttgat aaatcaactc tctgaccatt tgaagcattg gtttcaacat cttctttttc
     2881 tatcactgtt tcgacatttt ccaaatctcg tgcatagtaa tctcttggaa ttttttcttc
     2941 ttgcttatct ttcctttctt gttcttgctt attgccagaa agttcagtct ctgaagaagg
     3001 ctggctcttt tctgtatcag ttagggttga gctctccccc gaaagttgag tttcatttgc
     3061 cagaggttgc tcacttgccc cttcttgagc taaaacagga gacgttccaa ataccactgc
     3121 tcctacaatc atagaaaccg ctcctaccga tagtttccta atgctataac gacacttacg
     3181 ttcttgaaca ctccgattca tactgatcct ctctatatct atatcccgat ttctgaaata
     3241 agacatttac tccagaaaat gcacttagtt tgtcttttat taactttctt ttactacagt
     3301 tcatttaaat gacaaaaatg aactaaacaa actatctcaa attggtgcca attttcccct
     3361 ctcctttctc caatcagact cctgccaatc tagtttatct accaagacac cgctgcaatt
     3421 aaactaaaat atctctttat aagcaaatga tggacatcag cttatgctat ttacaccata
     3481 cttcctgctc aatccttatc gaacactttt tcaaatagct tttcataagc ataaatactt
     3541 gtagaaataa tgggaaatat aatcaagctc acaatcagaa tcttatccag cttaaagggg
     3601 acaatcccaa ataagtgaag aaataaatca atcagaaaac tgtcgaaaaa aactgtcaaa
     3661 agtagttcaa cttgtctttt tctctgcttt tttgtcttga atgccttaaa tatcatatta
     3721 ttcccctttt ctaagcttca atcccttctc tctatctgtt atttcgcata gctactacta
     3781 tttttacagc aatctatctt taaatataca taaagataga ttctatcact ttttataagt
     3841 gttagtaaat ttattatacc ttatttttaa aacgctttca atatagtgta atatagtaga
     3901 ttttagtttc aaaaaaatct tttatataat aatgtccttg aaagtagttt cagctgaaca
     3961 tttatagtcc ataaaaagaa aacagaaact catctgtttt tatactcaat aaaaatcaaa
     4021 gagcaaacta agaagctagc cgcatgatgc tcaaaacact gttttgaggt tgtagataag
     4081 actgac
//
LOCUS       DAVLMQ010000098         4068 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000098 DAVLMQ010000000
VERSION     DAVLMQ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.099"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            76..1335
                     /locus_tag="VXF95_002100"
     CDS             76..1335
                     /locus_tag="VXF95_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HEV1082575.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHIHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    1411..1546
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            1585..2085
                     /locus_tag="VXF95_002101"
     CDS             1585..2085
                     /locus_tag="VXF95_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HEV1082576.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            2161..2529
                     /gene="rplL"
                     /locus_tag="VXF95_002102"
     CDS             2161..2529
                     /gene="rplL"
                     /locus_tag="VXF95_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HEV1082577.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            2716..2886
                     /locus_tag="VXF95_002103"
     CDS             2716..2886
                     /locus_tag="VXF95_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082578.1"
                     /translation="MQKEGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVGILVLEGQ"
     gene            2886..3134
                     /locus_tag="VXF95_002104"
                     /pseudo
     CDS             2886..3134
                     /locus_tag="VXF95_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017648301.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
     gene            3148..3488
                     /locus_tag="VXF95_002105"
                     /pseudo
     CDS             3148..3488
                     /locus_tag="VXF95_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812122.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3481..3861
                     /locus_tag="VXF95_002106"
     CDS             3481..3861
                     /locus_tag="VXF95_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HEV1082579.1"
                     /translation="MIDLYLSKNRQRNQLLLDFFQNYGIEVSCHSVSEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFVEIILKNPELTIRLPLAVSNKRVYPSLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            3874..4017
                     /locus_tag="VXF95_002107"
     CDS             3874..4017
                     /locus_tag="VXF95_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082580.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRH"
BASE COUNT         1304 a          715 c          873 g         1176 t
ORIGIN      
        1 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
       61 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
      121 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
      181 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
      241 attatgcctg gtttggtcaa ttgtcacatc cattctgcaa tgacaggtct gagagggatc
      301 cgagatgaca gcaatctcca tgaatggctc aatgactata tttggccagc agaatctgag
      361 tttactcccg acatgactac caatgcggtc aaagaagccc tgacagagat gctccagtca
      421 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
      481 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
      541 acagaaacaa ctgctgagac tataagtaga actcgatcca tcatagacga aatcttaaaa
      601 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
      661 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
      721 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
      781 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
      841 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
      901 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
      961 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     1021 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     1081 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     1141 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     1201 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     1261 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     1321 acagtagaac tttaaaagaa aaattacgaa aaattttaaa aaaagtttgc aaaaatcttg
     1381 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     1441 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     1501 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     1561 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     1621 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     1681 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     1741 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     1801 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     1861 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     1921 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     1981 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     2041 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctatacag
     2101 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     2161 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     2221 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     2281 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     2341 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat cactggtctt
     2401 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     2461 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     2521 cttaaataat agagtatcgc aatttgattg cggaatccct atttaccagt ctttgagagc
     2581 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     2641 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     2701 gtttcggagg taattatgca aaaggaagga cagtcatcac gtcaattcgt gaagagtcat
     2761 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     2821 caagtaggtt taatccgatt tgatgaattt ggaaatgttg gaattttagt cttggaggga
     2881 caataatgaa gcgtattacc gctaatcaat atcagacatc agagcgttat tataagctcc
     2941 ccaaactttt atttgagagt gaacggtata agaatatgaa actggaggtt aaggtggttt
     3001 actcagtttt aaaagatcgg ttggagttgt ctttgagcaa aggttggatt gatgaggatg
     3061 gggctattta tttgatttat tccaattcaa atttgatggc acttttaggc tgttcaaagt
     3121 caaaattact ctccatgtga gtttgaagtg acatttttag atgattacca taaaaaacat
     3181 aactacccac tattttacga atcctatctt caaaacgtta tggaattcct tgaaagtcaa
     3241 gacataaaga atggggttga tgcctttgta gatgatcatc aaaatctcgt ttttgtttta
     3301 tatggacaag gctatcgagc cgagggaaaa gagggaatac ttacaaccca agtaactgta
     3361 aaagcttatg atgaagacaa gaaaccgatt aacttcgcaa atttattaga ttccttaatt
     3421 tattagattc cttaatcgtg tcagaatatc aaatggaacc gaatctttgg gaggtctccc
     3481 atgattgatc tctatctaag taaaaataga caaagaaatc aacttctttt agatttcttc
     3541 caaaactatg gcatagaggt atcttgtcat tcagtttctg aaatgacaaa ggacaaatta
     3601 attgagatga tgagctattc ttcagattgt tttgagtttt tatctcccaa tttattacga
     3661 tttaagaacc gtgacaatct aagattaacg gatttcgttg agataatttt aaaaaatcct
     3721 gaactaacca tcagacttcc tcttgcggtt tcaaataagc gagtttatcc aagtctgaat
     3781 ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta catggcgcaa
     3841 acacattatt tatctaacta aaggagaagc aatatggctg aacgattttg ggagaacttg
     3901 tccattattt tggctgaaag aaatatcagc tggattgagt taaccagaaa aatgtttgcg
     3961 ggagagtttc actatccaag tgaattgaat cgtttgtatc aaaagattcg ccactagaag
     4021 atggaacaat gaatgcctca aagtccatgg gtagaaagga ttgtgcag
//
LOCUS       DAVLMQ010000099         3924 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000099 DAVLMQ010000000
VERSION     DAVLMQ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3924
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.100"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            56..2236
                     /locus_tag="VXF95_002108"
     CDS             56..2236
                     /locus_tag="VXF95_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1082581.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDASQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKDLTEEVYSVADGQVVALEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     NAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            2288..3103
                     /locus_tag="VXF95_002109"
     CDS             2288..3103
                     /locus_tag="VXF95_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1082582.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAVLNWK"
     gene            3309..>3924
                     /locus_tag="VXF95_002110"
     CDS             3309..>3924
                     /locus_tag="VXF95_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000465984.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HEV1082583.1"
                     /translation="MFFQDRKIKYSIRKLSVATVSLAIGFLFAPAALGVAQVAQADEL
                     STTEQVENKAENQVSVVSFATEQEESETTYVDTTNKVTWTFAGYDKEKIVVGKGRQTF
                     LGSWVPTPNPEYVFKSSKAGVPLPQSILGMLPKDEASYKVGDTIVAKQPAVESVVEEE
                     KDYVWTFKGYDQKNATYNGKRVTFTGIWEVTPRPHHVSYTFVSVT"
BASE COUNT         1189 a          715 c          859 g         1161 t
ORIGIN      
        1 aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa ataaaggaga tttgaatgat
       61 gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg caaaaattcg gtaaggcttt
      121 gatggtagtt atcgcggtta tgccggctgc tggtttgatg atttcaatcg gtaagtctat
      181 cgtgatgatt aacccaacct ttacaccact tgtcatcaca ggtggaattc ttgagcaaat
      241 cggttggggg gttatcggta accttcacat tttgtttgcc ctagccattg gaggaagctg
      301 ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt gccttcatct tgattaaccg
      361 tatcactggt acaatttttg gtgtatcagg cgatatgttg aaaaatccag atgctatggt
      421 aactactttc tttggtggtt caatcaaagt tgctgattac tttatcagtg ttcttgaagc
      481 tccagccttg aacatggggg tattcgtagg gattatctca ggttttgtag gggcaactgc
      541 ttacaacaaa tactacaact tccgtaaact tcctgatgca ctttcattct tcaacgggaa
      601 acgtttcgta ccatttgtag ttattcttcg ttcagcaatc gctgcaattc tacttgctgc
      661 tttctggcca gtagttcaaa caggtatcaa taacttcggt atctggattg ccaactcaca
      721 agaaactgct ccaattcttg caccattctt gtatggtact ttggaacgtt tgctcttgcc
      781 atttggtctt caccacatgt tgactatccc aatgaactac acagctcttg gtggtactta
      841 tgacatttta actggtgcag ctaaaggtac tcaagtattc ggtcaagacc cactatggct
      901 tgcatgggta acagaccttg taaaccttaa aggtactgat gctagtcaat accaacactt
      961 gttagataca gtacatccag ctcgtttcaa agttggacaa atgatcggtt cattcggtat
     1021 cttgatgggt gtgattgttg ctatctaccg taatgttgat gctgacaaga aacataaata
     1081 caaaggtatg atgattgcaa cagctcttgc aacattcttg acaggggtta ctgaaccaat
     1141 cgaatacatg ttcatgttca tcgcaacacc tatgtatctt gtttactcac ttgttcaagg
     1201 tgctgccttc gctatggctg acgtcgtaaa cctacgtatg cactcattcg gttcaatcga
     1261 gttcttgact cgtacaccta ttgcaatcag tgctggtatt ggtatggata tcgttaactt
     1321 cgtttgggta actgttctct ttgctgtaat catgtacttt atcgcaaact tcatgattca
     1381 aaaattcaac tacgcaactc cagggcgcaa cggaaactac gaaactgctg aaggttcaga
     1441 agaaaccagc agcgaagtga aagttgcagc aggctctcaa gctgtaaaca ttatcaacct
     1501 tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt atgactcgtc ttcgtgtaac
     1561 tgttaaagat gcagataaag taggaaatgc agagcaatgg aaagcagaag gagctatggg
     1621 tcttgtgatg aaaggacaag gggttcaagc tatctacggt ccaaaagctg acattttgaa
     1681 atctgatatc caagatatcc ttgattcagg tgaaatcatt cctgaaactc ttccaagcca
     1741 aatgactgaa gcacaacaaa acactgttca cttcaaagat cttactgagg aagtttactc
     1801 agtagcagac ggtcaagttg ttgctttgga acaagtaaag gatccagtat ttgctcaaaa
     1861 aatgatgggt gatggatttg cagtagaacc tgcaaatgga aacattgtat ctccagtttc
     1921 aggtactgta tcaagcatct tcccaacaaa acatgctttt ggtattgtga cggaagcagg
     1981 tcttgaagta ttggttcaca ttggtttgga cacagtaagt cttgaaggta aaccatttac
     2041 agttcatgtt gctgaaggac aaaaagttgc agcaggagat ctccttgtca cagctgactt
     2101 gaatgctatc cgtgcagcag gacgtgaaac ttcaacagta gttgtcttca caaatggtga
     2161 tgcaattaaa tcagttaaat tagaaaaaac aggttctctt gcagctaaaa cagcagttgc
     2221 taaagtagaa ttgtaatata cttgaggttg gaagctgtat tccaacctct tattttggga
     2281 gaaaagaatg aaatttttaa cactcaatac tcacagttgg atggagaaag aagcagagga
     2341 aaaattccag attttgcttg aagatattct tgaaaaggac tatgatttga tttgttttca
     2401 agaaatcaat caggagatga cctcgtcaga ggtggaggtt aatgaccttt atcaagcttt
     2461 gccagcagct gagcctattc accaagacca ttatgttaga ctcttggttg aaaagttgtt
     2521 agagcaaggg aaaaattact actggacctg ggcttataac catatcggct atgaccgcta
     2581 ccacgaaggt gtggctatct tgtctaaaac acctattgaa gccagagaaa ttttggtttc
     2641 agatgtggat gatccaacag actatcatac tcgccgtgtt gccctagctg aaactgtagt
     2701 cgatggcaag gagctagcag ttgccagtgt tcatctctct tggtgggata aaggtttcca
     2761 agaagaatgg gcacgatttg aggctgtctt gaaaaaattg aacaagccac ttttactagc
     2821 tggagatttt aacaacccag caggtcagga aggttaccaa gctattttag ctagtccatt
     2881 aggcttacaa gacgcatttg aagttgctca agagaaaagt ggtagctata ctgttccgcc
     2941 tgaaattgat ggctggaaag ggaacactga accccttcga atcgattatg tctttactac
     3001 caaagagtta gcggtggaaa atttacatgt cgtatttgat ggtaacaaga gtccacaagt
     3061 gagtgatcac tatggcttga atgcggtatt aaattggaaa taaaatcaaa aaatgaaagg
     3121 gagcgagtcc tttcattttt ttacaaaaat ccctataatt actattttgg agaaggagtt
     3181 ttttgtatat ttgtatatta tgaggaaata tccacaaata agtttttaaa actttacggt
     3241 caaaaaaaaa tcgctaatat taactattta tgatagaatg aaaattatga aataaaagga
     3301 ggactggaat gttttttcag gatagaaaga taaaatattc aatccgcaaa ttgtcagttg
     3361 ctactgtgtc ccttgcgatt ggatttttgt ttgcgcctgc ggcgcttgga gtcgctcaag
     3421 tagctcaagc tgatgagctt tcaactactg aacaagtgga gaataaagca gagaatcagg
     3481 tctcggtggt ctcttttgca acagagcaag aagaaagtga aacgacttat gttgatacga
     3541 cgaataaagt gacttggaca tttgcaggat acgataaaga aaaaattgtt gtaggaaaag
     3601 gcagacagac tttccttgga agctgggtac ctactccaaa tccagaatat gtattcaaat
     3661 catctaaagc aggtgttcca ttaccacaaa gtattttggg aatgcttcca aaggatgaag
     3721 cttcttataa ggttggtgac accattgtag ccaaacaacc tgctgtagaa tcagtagtcg
     3781 aagaagaaaa agactatgtc tggaccttca aaggttatga tcagaagaat gcgacgtaca
     3841 atggcaagcg tgtgacattt acaggtatct gggaagtaac gcctagaccg catcatgtaa
     3901 gctatacttt tgtaagtgtt acat
//
LOCUS       DAVLMQ010000100         3923 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000100 DAVLMQ010000000
VERSION     DAVLMQ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3923)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3923)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3923
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.101"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(96..1511)
                     /locus_tag="VXF95_002111"
     CDS             complement(96..1511)
                     /locus_tag="VXF95_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HEV1082584.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLLGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEH
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     EEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1524..3362)
                     /locus_tag="VXF95_002112"
     CDS             complement(1524..3362)
                     /locus_tag="VXF95_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HEV1082585.1"
                     /translation="MSYKDTVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGAPVTPASYGSSVVPILIMV
                     WLMKYIEKIIAKLTPAITKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     GVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVEAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3380..>3923)
                     /locus_tag="VXF95_002113"
     CDS             complement(3380..>3923)
                     /locus_tag="VXF95_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HEV1082586.1"
                     /translation="HISSSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKE
                     LGIELPIDEAAFIALHFVNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDY
                     YRFITHIKLFAHRLVENTTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLL
                     TSSELVYLMAHIRRLTKNLD"
BASE COUNT         1305 a          780 c          526 g         1312 t
ORIGIN      
        1 agaggtttag aatttgatgt cttccaaacc tctttatttc atatttaatg agatgttgcc
       61 ttaaccgtga taatatctaa tcatcaataa acaaactatt tgaataagga ttctccattt
      121 gattcaatca ctcctttata ccaagtaaag gacattttct tatatcgatt gaatgtgcca
      181 tttccatcat catttcgatc aacataaatg agaccgtacc ttttagaaag ttgtgcagtg
      241 gacatagaaa cgcagtcaat acatccccaa gatgtatagc ccataatttc cacaccatct
      301 tgtagagctt cagctacttg caataaatgt tcttccatat actgaattct ataatcatct
      361 tggactgtta agttattaaa ttcatctttt attagttgat ctttagcacc taatccgttt
      421 tccactataa ataatggaat ttgataacgg tcataatatc tatttaaaat tatacgtagt
      481 ccaattggat caatttgcca tccccactca gaagactcta aataaggatt tactaagcca
      541 ccaataatat tcccttctcc tgaattatac tgtgttggaa gagcagattg agtcacactc
      601 atgtaatagc taaaggataa aaaatctaca gtataatttt ttaataactc tgcatcttca
      661 gctgcaaact ctatgttaat gtcatgttcc ttaaaatatc tttttgcata attcggataa
      721 taacctctaa catgcacatc tgaaaataga taatttagat tctcatactc atgagtcgcc
      781 catacatctt ttggatttgg agtcattgga taagctggca tagctaatac catacacccc
      841 accttaaact ctgaattaat ctcacgagca atttttgtaa ccaaactcga ggcgactaat
      901 tcatgatgta tagcttgata taattcttgt ttcgaaagat tctccttagg tatatctatt
      961 cctccactag taaacggtaa ttccaaaaca gagtttactt cgttaaatgt aagccaatat
     1021 ttaactttat ctttatacct ttctaaaact gttcgagcaa atttttcata aaaatgaatc
     1081 attctcctat caatccatcc atgatatttt cttgctaaat ataatggagt ctcatagtgt
     1141 gaaagagtta caagtggttc tatcccgtga gcatgtagtt catcaaataa ttcatcataa
     1201 tatttcaacc cagcttcgtt aggttcttct tcatctcctt ttggaaaaat tctactccat
     1261 gcaatagaag tacgaaaaac attaaagccc atttcagaaa acaaggatat atcttcctta
     1321 tatttatgat aaaaatcaat acctaacaat tttaagttat cttctgtagg attttctgtt
     1381 gcttctccta atccaccttt gggtaacaca tcctgaactg ataatccctt accatcttca
     1441 ttatatgctc cctctacttg attagctgca accgctccac cccaaagaaa atcatctgga
     1501 aaaatggtca taactttcct ccattataat attaccagta attccttaga atgctcgatt
     1561 gtctgattat taggtaatac taatacatct agaaaatcat tggtattcgt tacaattact
     1621 ggtgtaactg tttcgtagcc tttagtcttg attaaattca agtccatttc aaaaatcaac
     1681 tgatttttga aaactctgtc tccttcttct acatgactaa taaaaccttg accttttagc
     1741 tcaacagtat ctaatccaat atgaattagt aactcaacac cctcatcact cttcaatcca
     1801 attgcgtgct tagtcggaaa aatatttgta attttcccat caaatggtgc ataaacctta
     1861 ccttcacttg ggataatcgc tactccgtct ccaattagtt tatctgaaaa tgttttatcc
     1921 tggacatcgc ttaacggaat gatttctcct gatataggag aaaatatcat ttttttattt
     1981 gaaactccag cttcaacttc taaattgcta gaactctctt cttcatcgat tccaaatata
     2041 taagctaata caaaggtaat aacaaccgaa atgaccgcca caattaaagc atttacaata
     2101 tttgatggca catcagaata aataaattga ggcaacgcta tcaaagatgg gacagcaaat
     2161 agatatgctt taacactagt aagacctgca aataatcccg ctaatccacc accaatcata
     2221 gctgcataaa gcggtttttt atattttaaa gtcacaccat ataatgcagg ttcggtaatc
     2281 cctgcaagta aggctgagaa acctgctgca aaagcaattt gttttgtatt attattttta
     2341 ctctttaatg caacagccat cgaagcagcc ccttgagcta agtttgaccc taacattgct
     2401 ggaagaatta atacgtctgg agtagcaata gatgccgcca aaaaaatagg tgcaaaagcc
     2461 caatgcattc cagtcataac aataaatggc ataatagcac caagaatagc taatgtaagc
     2521 catccagcta caccatacat ttgcccaact agatttgata atccttcacc aacaattact
     2581 ccaataggtc cgactacaac taaggcaata cagcttgata ctaataatac tagcgtaggt
     2641 tgcaaaaaac tcttagtaat agctggtgtt aatttagcaa ttattttttc aatatatttc
     2701 atcaaccaaa ccataataag aattggaacg actgatgaac cataactagc tggtgtcaca
     2761 ggtgcaccaa ataaactaag aggattccct gattgcacca tttgaacaaa atttggatgg
     2821 agaagtacac ctgctacaga catagctaat gtagatgtta cttttaattt ttgtgatgca
     2881 gaataagcta ataacagcgg taagaaataa tatggagcat ccccaaaaaa tgtcaaaaaa
     2941 gcaatagtct gagaatctga ttgcaatata ccaagcattg gtaaaatgat taccaagact
     3001 ttcaacatac ctccccctaa cattgctgga atgattggag tcatggaacc agcgatatac
     3061 tcaatgattc tttctaaaat attccctttg tgcccttgaa caactgaatc ggattcaaaa
     3121 ttgccaagtt taacgaattc tttataataa ttagctacat cattaccaag tataatttga
     3181 tattgtccat tctttttcat aatacctatt acacctggta tcttcttcac atcatcatca
     3241 ttgactaaat tttcatcttt taattctaat cttaaacgtg ttacacaatg ggtaactcta
     3301 ttgacatttt tttcacctcc aattacatcg aggatttttt gtaccgtatc tttataactc
     3361 atggtattct cctattctat taatctaaat tttttgttaa gcgacgaata tgagccatca
     3421 aataaactaa ttcactagaa gtcagcaaat aattgtactc cgtttgtata aacattgcca
     3481 cctgttcacc acattcatat tctctaggat atttattttt cattaatgct aacaagtctt
     3541 catcatcatc gtcacaataa gttgtatttt caaccaagcg atgggcaaat aattttatat
     3601 gagttatgaa tctataataa tcaatagaat cttggttaaa ctcagtacaa tagaaatctt
     3661 gaatgatttt ctcaattccc ataattattt cagtgatttt atacgactct tgaaaattat
     3721 tttctaaatt agcattaaca aaatgtagcg ctatgaatgc agcttcgtca attggaagtt
     3781 caatacctaa ctcttttttt attatttgta aagccctttt cccaagttca aattcttctt
     3841 tataatattt cgagatttcc cagcgtaggg gattcgaaat aataactcct tctttataac
     3901 gttctatgct cgaagaaata tga
//
LOCUS       DAVLMQ010000101         3863 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000101 DAVLMQ010000000
VERSION     DAVLMQ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.102"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..408
                     /locus_tag="VXF95_002114"
     CDS             <1..408
                     /locus_tag="VXF95_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1082587.1"
                     /translation="KPQTEKPEEDKEHDEVSEPTHPESDEKENHAGLNPSADNLYKPS
                     TDTEETEEEAEDTTDEAEIPQVEHSVINAKIAEAEALLEKVTDSSIRQNAMETLTGLK
                     SSLLLGTKDNNTISAEVDSLLALLKESQPAPIQ"
     gene            619..3738
                     /gene="phtE"
                     /locus_tag="VXF95_002115"
     CDS             619..3738
                     /gene="phtE"
                     /locus_tag="VXF95_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HEV1082588.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
BASE COUNT         1446 a          631 c          752 g         1034 t
ORIGIN      
        1 aaacctcaga cagaaaaacc tgaggaagat aaggaacatg atgaagtaag tgagccaact
       61 caccctgaat ctgatgaaaa agagaatcac gctggtttaa atccttcagc agataatctt
      121 tataaaccaa gcactgatac ggaagagaca gaggaagaag ctgaagatac tacagatgag
      181 gctgaaattc ctcaagtaga gcattctgtt attaacgcta agatagcaga ggcggaggcc
      241 ttgctagaaa aagtaacaga ttctagtatt agacaaaatg ctatggagac attgactggt
      301 ctaaaaagta gtcttcttct cggaacgaaa gataataata ctatttcagc agaagtagat
      361 agtctcttgg ctttgttaaa agaaagtcaa ccggctccta tacagtagta aaatgaatgg
      421 agcatatttt atggagaagt aacctttcgt gttacttctc ttttttagaa aaacgtaaca
      481 gaaacttgac aaaagtaatt ttaaatagta gactatttac tggttaatta aatggttaaa
      541 taatcggttt agaaaactat ttaataaagt aaaagaagtt gagaaaaaaa cttcatcatt
      601 tattgaaatg agggatttat gaaatttagt aaaaaatata tagcagctgg atcagctgtt
      661 atcgtatcct tgagtctatg tgcctatgca ctaaaccagc atcgttcgca ggaaaataag
      721 gacaataatc gtgtctctta tgtggatggc agccagtcaa gtcagaaaag tgaaaacttg
      781 acaccagacc aggttagcca gaaagaagga attcaggctg agcaaattgt aatcaaaatt
      841 acagatcagg gctatgtaac gtcacacggt gaccactatc attactataa tgggaaagtt
      901 ccttatgatg ccctctttag tgaagaactc ttgatgaagg atccaaacta tcaacttaaa
      961 gacgctgata ttgtcaatga agtcaagggt ggttatatca tcaaggtcga tggaaaatat
     1021 tatgtctacc tgaaagatgc agctcatgct gataatgttc gaactaaaga tgaaatcaat
     1081 cgtcaaaaac aagaacatgt caaagataat gagaaggtta actctaatgt tgctgtagca
     1141 aggtctcagg gacgatatac gacaaatgat ggttatgtct ttaatccagc tgatattatc
     1201 gaagatacgg gtaatgctta tatcgttcct catggaggtc actatcacta cattcccaaa
     1261 agcgatttat ctgctagtga attagcagca gctaaagcac atctggctgg aaaaaatatg
     1321 caaccgagtc agttaagcta ttcttcaaca gctagtgaca ataacacgca atctgtagca
     1381 aaaggatcaa ctagcaagcc agcaaataaa tctgaaaatc tccagagtct tttgaaggaa
     1441 ctctatgatt cacctagcgc ccaacgttac agtgaatcag atggcctggt ctttgaccct
     1501 gctaagatta tcagtcgtac accaaatgga gttgcgattc cgcatggcga ccattaccac
     1561 tttattcctt acagcaagct ttctgcctta gaagaaaaga ttgccagaat ggtgcctatc
     1621 agtggaactg gttctacagt ttctacaaat gcaaaaccta atgaagtagt gtctagtcta
     1681 ggcagtcttt caagcaatcc ttcttcttta acgacaagta agaaactctc ttcagcatct
     1741 gatggttata tttttaatcc aaaagatatc gttgaagaaa cggctacagc ttatattgta
     1801 agacatggtg atcatttcca ttacattcca aaatcaaatc aaattgggca accgactctt
     1861 ccaaacaata gtctagcaac accttctcca tctcttccaa tcaatccagg aacttcacat
     1921 gagaaacatg aagaagatgg atacggattt gatgctaatc gtattatcgc tgaagatgaa
     1981 tcaggttttg tcatgagtca cggagaccac aatcattatt tcttcaagaa ggacttgaca
     2041 gaagagcaaa ttaaggctgc gcaaaaacat ttagaggaag ttaaaactag tcataatgga
     2101 ttagattctt tgtcatctca tgaacaggat tatccaggta atgccaaaga aatgaaagat
     2161 ttagataaaa aaatcgaaga aaaaattgct ggcattatga aacaatatgg tgtcaaacgt
     2221 gaaagtattg tcgtgaataa agaaaaaaat gcgattattt atccgcatgg agatcaccat
     2281 catgcagatc cgattgatga acataaaccg gttggaattg gtcattctca cagtaactat
     2341 gaactgttta aacccgaaga aggagttgct aaaaaagaag ggaataaagt ttatactgga
     2401 gaagaattaa cgaatgttgt taatttgtta aaaaatagta cgtttaataa tcaaaacttt
     2461 actctagcca atggtcaaaa acgcgtttct tttagttttc cgcctgaatt ggaaaaaaaa
     2521 ttaggtatca atatgctagt aaaattaata acaccagatg gaaaagtatt ggagaaagta
     2581 tctggtaaag tatttggaga aggagtaggg aatattgcaa actttgaatt agatcaacct
     2641 tatttaccag gacaaacatt taagtatact atcgcttcaa aagattatcc agaagtaagt
     2701 tatgatggta catttacagt tccaacctct ttagcttaca aaatggccag tcaaacgatt
     2761 ttctatcctt tccatgcagg ggatacttat ttaagagtga accctcaatt tgcagtgcct
     2821 aaaggaactg atgctttagt cagagtgttt gatgaatttc atggaaatgc ttatttagaa
     2881 aataactata aagttggtga aattaaatta ccgattccga aattaaacca aggaacaacc
     2941 agaacggccg gaaataaaat tcctgtaacc ttcatggcaa atgcttattt ggacaatcaa
     3001 tcgacttata ttgtggaagt acctatcttg gaaaaagaaa atcaaactga taaaccaagt
     3061 attctaccac aatttaaaag gaataaagca caagaaaact caaaacttga tgaaaaggta
     3121 gaagaaccaa agactagtga gaaggtagaa aaagaaaagc ttcctgaaac tgggaacagt
     3181 actagtgatt caacgttaga agaagttcct acagtggatc ctgtacaaga aaaagtagca
     3241 aaatttgctg aaagttatgg gatgaagcta gaaaatgtct tgtttaatat ggacggaaca
     3301 attgaattat atttaccatc gggagaagtc attaaaaaga atatggcaga ttttacagga
     3361 gaagcacctc aaggaaatgg tgaaaataaa ccatctgaaa ctggaaaagt atctactgga
     3421 acagttgaga accaaccaac agaaaataaa ccagcagatt ctttaccaga ggcaccaaac
     3481 gaaaaacctg taaaaccaga aaactcaacg gataatggaa tgttgaatcc agaagggaat
     3541 gtggggagtg accctatgtt agatccagca ttagaggaag ctccagcagt agatcctgta
     3601 caagaaaaat tagaaaaatt tacagctagt tacggattag gcttagatag tgttatattc
     3661 aatatggatg gaacgattga attaagattg ccaagtggag aagtgataaa aaagaattta
     3721 tctgatctca tagcgtaagg aatagcagta gaaaaagtct gaatcaaaaa tgaagttctc
     3781 tcaaaagtta gaaataaaac tctgactttg ggagaatttc attttattat taatatataa
     3841 aatttcttga catacaactt aaa
//
LOCUS       DAVLMQ010000102         3861 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000102 DAVLMQ010000000
VERSION     DAVLMQ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3861
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.103"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..1165
                     /locus_tag="VXF95_002116"
     CDS             <1..1165
                     /locus_tag="VXF95_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082589.1"
                     /translation="AGADGRTPYVHFAYSENADGSGLTMTDNGQRYFGHYSDYEKPDS
                     SDKTKYKWADRWAKVDGGYVNIYALSKNRSIGKSYHVSEFNMDVLSGNITLKAIGSDP
                     YIGAVSSHPGIFIKQQGMKIPVIQGRSICITITNPLFRKNYISFFNSLGKTVKTYKHY
                     NTNKFLISSADLVGVEFIALRYGAGSSNIQIGTVLETKVKVEYGTVHSDWSPAPEDIE
                     SNINSKADQGLTQEQLNALNEKSQILEAEMKAKASMEAFSELEKAYNAFVKLNADSQK
                     KSESDLVEAGRRIDLLTTQFGGLAELKTFIDTYMKSTNEGLIIGKNDASSTIKVSSDR
                     ISMFSAGKEVMYISQGVINIDNGIFTASIQIGRFRTEQYHLNKDVNVIRYIGG"
     gene            1177..3255
                     /locus_tag="VXF95_002117"
     CDS             1177..3255
                     /locus_tag="VXF95_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="structural protein"
                     /protein_id="HEV1082590.1"
                     /translation="MTKFINSSGSLHLNIYIEQVSQDIANNSSRVSWKATVDRDGAYR
                     TYTYGNISNLSVWLNGSSVHSSHPNFDTSGQEFTLASGEVTIPHSGDGTKTFAVWASF
                     DPNNGVHGNITVSANYTLSSIPRSSSVSDNALSGNRRLGSPHTLTIDRKSSLFTHQVW
                     YRVFGSNWIDLGKNHATGVSFVPNIDLARYNTKAKSGTMDICVRTYNGTTQVGNDVYS
                     NGWYFEIPESVKPTFSGITLTDMNTVARQLLSGNNFLQIISDIQVNFNNPSGAYGSTI
                     TGYRAEIVNKNQVTTVNGGRLGMMNFNGSATIRASVVDSRGRQSDTRDITINVIEYFA
                     PAFSFTAFRTRETPNIIQVVRNAKIAPITLSGSQKNVMTLSFKVARLGSTTFTADHGR
                     ASGIWTTQHTLNNSAANMAGNYVATKSFVVIGTLSDKFTSTEFTATVATESVVMSYDK
                     DGRVGIGKVAEQGGAGSLDVLGDIYARNKPIQQYQLTDNNGCGKLIKQDFNTMKETGT
                     WWINGSSQNNPFSGTWGMLEVFRPNPGSHERIQRFTTSTGYMAVRENGFDNNWRPWRY
                     LVQQSKSTNNSDYVALLKSESTPTPWQNAILQNGWNHHRDYGGVQFSKTFDGVVCFKG
                     TCKGGKIARESIILTLPEHFRPSTTLFKTALNNDYGSAVIGIYPNGNVVVKSNVDATW
                     LNFDNVFFKI"
     gene            3315..3578
                     /locus_tag="VXF95_002118"
     CDS             3315..3578
                     /locus_tag="VXF95_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082591.1"
                     /translation="MLKVTKTRQLVTEFFAQDGDQQKLVKTTVINTDNKAVSTISETL
                     HDPELYANNRISMRKHEQELREMRYKIEDAILAELEADAEHKE"
     gene            3588..>3861
                     /locus_tag="VXF95_002119"
     CDS             3588..>3861
                     /locus_tag="VXF95_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HEV1082592.1"
                     /translation="MKIEFFNFLRSVVQTEDGLVLYALTLIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSI"
BASE COUNT         1281 a          648 c          810 g         1122 t
ORIGIN      
        1 ggctggtgca gatggtagga caccttatgt tcactttgcg tattctgaaa atgcagatgg
       61 atcaggtttg acaatgacag ataacggaca gcgttatttt ggtcattatt cagattatga
      121 gaaacctgat agttcggata aaactaagta caaatgggct gatcgttggg ctaaagttga
      181 tggaggttat gtaaatatct atgcattgtc taagaataga agtattggga aatcttatca
      241 tgtttctgaa tttaatatgg atgtactttc aggaaatatc actctaaaag caattgggtc
      301 agatccatac attggcgccg tttcttctca tccaggtatt tttataaagc aacagggaat
      361 gaaaatccca gttatacaag ggagatctat ttgtataaca ataacaaatc ctttatttag
      421 aaaaaattac atctcgtttt ttaattcatt aggtaaaact gttaaaacat ataagcatta
      481 caacacaaat aaatttttaa tatcttcagc tgatttggta ggtgttgaat ttatcgcttt
      541 acgatatggt gcaggaagct cgaatataca aattggaacc gtactagaga caaaagtaaa
      601 ggtagaatat ggaaccgtgc atagcgactg gtcgcccgct ccagaagata ttgaaagtaa
      661 tattaactct aaagctgatc aggggctgac tcaagagcag ttaaatgccc tcaatgagaa
      721 gtcacagatt ttagaggctg aaatgaaagc gaaagcatcg atggaggcct ttagtgaatt
      781 agaaaaagca tataatgcct ttgtgaaatt aaatgcagat agtcaaaaaa aatctgagtc
      841 tgatttagtt gaagcaggta gaagaattga tttgctgacg acacaatttg gaggattagc
      901 agagcttaaa acattcattg atacttacat gaaaagcaca aatgagggct tgattatagg
      961 taagaatgat gcaagctcta ctattaaggt atcaagtgat agaatatcca tgttttctgc
     1021 aggtaaggaa gttatgtaca tttcgcaagg tgtaataaat attgataatg gtatttttac
     1081 tgcatcaatt caaattggac gttttagaac agaacagtat catcttaaca aagatgtgaa
     1141 tgtcatacga tatataggag gttaaaaaag agggaaatga ctaaatttat caattctagc
     1201 ggttcactac acttgaatat ttacatcgaa caagttagtc aagatatcgc taacaattcc
     1261 tcaagagtta gttggaaagc tactgttgac cgtgatggag cttaccgcac atatacttat
     1321 ggtaatatta gtaacttgtc tgtatggtta aatgggtcaa gtgtgcatag tagtcatcca
     1381 aactttgaca catccgggca agagtttact ttagcaagtg gggaagtaac catcccacac
     1441 agtggtgacg gaactaagac ttttgcagta tgggcatcgt ttgacccaaa caacggagta
     1501 catggaaaca ttaccgtgtc agcaaactat actctttcaa gcattcctcg atctagtagt
     1561 gtaagcgaca atgctctttc aggaaatagg cggctcggaa gtcctcacac tctcactatt
     1621 gatcgcaaat ctagcttatt tactcaccaa gtatggtata gagtgtttgg tagcaactgg
     1681 attgatttag gaaaaaatca cgcaacaggc gtttctttcg tacctaatat tgacctagct
     1741 agatacaaca caaaagcaaa gtctggcacg atggacatat gtgttcgaac atataatgga
     1801 actactcaag ttggaaatga cgtttactca aatgggtggt attttgaaat tccggaaagc
     1861 gtgaaaccta cattttctgg aattacattg actgatatga atactgttgc taggcaacta
     1921 ttgagcggaa ataacttttt acagattatt tccgacattc aggtcaactt taataatcca
     1981 tccggggctt atggttcgac tatcacagga tatcgtgctg aaatcgtaaa caagaatcag
     2041 gttacaactg taaacggtgg taggcttggt atgatgaatt tcaatggttc agcaacgatt
     2101 cgagctagtg tggttgatag ccgaggcagg caatcagata ctagagatat tacaatcaat
     2161 gttattgaat attttgcacc agcttttagt tttacagctt ttaggacgcg ggaaacacct
     2221 aacattattc aagttgtcag gaatgctaaa atcgctccta tcactttatc aggtagtcaa
     2281 aaaaatgtca tgacactatc attcaaagta gctcgactag gtagtacaac ttttacagct
     2341 gatcatggta gagcttctgg tatttggaca actcaacaca ccttaaataa ttcagctgct
     2401 aacatggcag gtaattatgt tgcaaccaaa tcatttgtgg tcataggaac tctatctgat
     2461 aagtttacaa gcacagaatt tacagcaaca gttgcaactg aaagtgtggt aatgagttat
     2521 gacaaagatg gccgtgtggg cattggtaaa gttgcagagc aaggtggtgc agggtcattg
     2581 gatgtcttgg gagatatcta cgctagaaat aaacctattc aacaatatca attgactgac
     2641 aataatggat gtggaaaact tatcaaacag gattttaata cgatgaaaga gactggaacg
     2701 tggtggataa atggtagctc tcaaaacaac cccttttctg gaacttgggg gatgctagag
     2761 gtattcagac ctaatccagg ctctcatgaa cgtattcaac gcttcactac ctcaacagga
     2821 tatatggcag ttagggagaa tggttttgat aacaactgga gaccatggcg ctatctggtg
     2881 caacaatcca agtctactaa taactctgac tatgtagctt tgctaaaatc agaaagcact
     2941 ccgactcctt ggcaaaatgc cattttacaa aatggatgga atcatcacag ggattacgga
     3001 ggtgtccaat tttcaaaaac attcgatggt gttgtttgtt ttaaaggaac atgtaagggc
     3061 ggaaagattg cacgtgagtc aatcatactt actttacctg aacatttcag accatctaca
     3121 acattattca aaactgcttt gaataatgat tacggttcag ccgttatagg aatttatcca
     3181 aatggaaacg tagttgtcaa atctaatgta gatgctactt ggcttaattt tgataatgtg
     3241 tttttcaaaa tataacaacc gtaaaaaatc cctaattatt aacggataat taatttataa
     3301 aggaggaaat gacaatgtta aaagtcacta aaacacgtca gctagtaact gaatttttcg
     3361 cacaagatgg cgaccaacaa aaattggtca aaactactgt aatcaacaca gacaataaag
     3421 ctgtttcaac aatatctgaa acgctgcatg acccggaact gtacgctaac aatcgtatca
     3481 gtatgcgtaa gcatgagcaa gagttacgag aaatgcgcta taagattgaa gatgccattt
     3541 tggcagagct ggaagcagat gctgagcata aggaatagga ggtgtgtatg aaaattgaat
     3601 ttttcaattt tctaagaagt gtcgtacaga ctgaagatgg tttggtcttg tacgctctaa
     3661 cactgattgt ctcaatggaa atcattgatt ttgtgacagg gacgattgcg gcgattatca
     3721 atcctgacat cgagtacaag agcaaaatcg gcattaacgg gctccttcgt aagatttcag
     3781 gggttctctt actgatgatc ctcattccgg cgtccgtttt gttgcctgaa aagacaggtt
     3841 ttgtattctt gcattcaatc t
//
LOCUS       DAVLMQ010000103         3855 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000103 DAVLMQ010000000
VERSION     DAVLMQ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3855
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.104"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(119..1345)
                     /locus_tag="VXF95_002120"
     CDS             complement(119..1345)
                     /locus_tag="VXF95_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HEV1082593.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFAKFLLYSIVSLSLSGQSFSLL
                     LVAFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTINYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLKHTISIKTALYASLVTQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSIGAITVVLPSLFTIALVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            complement(1417..2082)
                     /locus_tag="VXF95_002121"
     CDS             complement(1417..2082)
                     /locus_tag="VXF95_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082594.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            complement(2150..2350)
                     /locus_tag="VXF95_002122"
     CDS             complement(2150..2350)
                     /locus_tag="VXF95_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone VP1"
                     /protein_id="HEV1082595.1"
                     /translation="MLNLQFAETMELTEAELETVYGGELGYNAVIPGGSWGGLGTSWS
                     ITNFWKKNFNDRPDFDSDRRRY"
     gene            complement(2636..3499)
                     /locus_tag="VXF95_002123"
     CDS             complement(2636..3499)
                     /locus_tag="VXF95_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HEV1082596.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRKVVDRFAHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKRYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKQGLLNILSELMERKLFLYIPIFE
                     AELESMLRPYDVFEKVSWQFLKKMSVFLQTKGSNQKEIERFTQSLQVLENPQLTSLFE
                     LRFQQYKELID"
BASE COUNT         1330 a          745 c          692 g         1088 t
ORIGIN      
        1 tactatttta gattcagttt actataacac attcagaaaa gagaaaaagt ctgttgattt
       61 tgaccatcat aaaaagactg gcaatccagt ctcaaacata tattatagaa attctccact
      121 aaatactttc acgaatattc agaagcataa caaaggcaac tagaagaaat agcaataaaa
      181 caaagctaac tgccagagtt ccaaagctag tagcaatggt taccaaagct attgtaaata
      241 agctaggtaa aacaaccgta atggcaccga tagaggattg aactgctccc attgactcct
      301 caggtatttg tttaaaaacg agttcttgca atctaggaga gagaacacct gcgaaaaagg
      361 catccaaggt actaaagatg agaatccagt caaaacgaac tgtggcaaat cctactagaa
      421 gaagcaactg ggtgacaagt gaggcataga gagctgtttt tatagaaatc gtatgtttca
      481 gatagccact tacaaggctt ccgacaatca gggctgacag ttcaaaagtg gatagcaagg
      541 caagagattg acctgtttgt aaattcaaaa agggttgatt cctcaaaaat agagtagaga
      601 caggaactgt aacatttatc actgcttgac tagtagagat aataaacaaa accaagagca
      661 ccttattcat attccatatc aatttcgatg attggagcaa atgctggcaa aaggatttta
      721 cagagagtcc ttcttgatag ttaatcgttt tttctacttt caagaggtca gtttttatga
      781 agaggatacc taaaaatgcg attaaaaagg taagagcgtt cagcaaggaa ataaactgga
      841 tggatagaat acctaataag actcctccta gaatattact gattgttttc actaaactaa
      901 cagttgactg tttaaatcca atagcttctg ccagatggtc ttgcccaata attctaatga
      961 aaatcggagt gagcatggcg cctgaaaaat aactcaacgt gtcagacaag aggttaatca
     1021 gacaaataaa tgctactaat aacaaggaaa aggactgccc tgaaagtgat aaagacacta
     1081 tagagtaaag caaaaatttt gcaaaactaa tgactgtgta tttcaagaca cgatgatgtt
     1141 gaaaatccgc caaaactccc agaaagattt gtagaacttg gggcagggtt tctgaaatcg
     1201 tgatgagtaa aatcgccaaa ggggcaaaag atgcatctgc cacataattc aggaaggcca
     1261 gataaaaaat cgtatcccca agcgttgaaa tccactggtt gatagttaat tgcctaaaat
     1321 ctctattttg aagaaatact ttcatcacaa ctccttctta agttcaaatg ggaatctttc
     1381 cccaaggata gaccgcgata ctactaacaa ccaaaattac agtaacatca aaagctgacc
     1441 aatgccattg tagactatat gcagtccaat aggccaataa attgactttg tcattctaaa
     1501 taagactgca aatataagac ctccacccat atagaagaca aagtctgtca agacccaacc
     1561 gtgattacta atgtgcgaga ccccaaataa aacagcggaa ccaagtacat ctagccccca
     1621 tttctttcct ttttccagag cagtcatcac taatccacga taaatcatgt cttcaaaaat
     1681 gggacctgca atcacaggat aaaaaaaata catcaaaaat gccgtagctc ctgtaaaagt
     1741 aggagcagca tgttgataag aaatttcatt tcgagtaggt gggaaaagaa aaaaggtgac
     1801 aaaattccaa gcaacaaaag caagcagagc taggaaggaa tagaaaagat aggatccttt
     1861 aaactttcta ctattgattt tctgccattt ccccgaccaa atcatagcaa taagagcaaa
     1921 taaaaccaca agaaaattca acatcatatc cgacagataa taggcaaagt cagatagccc
     1981 agcaacaagg tcgctgcgta aaactaaaac actgaacttc tggtcagcaa taactagtag
     2041 aaaaactata ataaagtagc ggtgtgagat tatctttttc attctatttc ctcctataca
     2101 tatgaaataa agacagcccc tacccaagaa aaggcaaggg ctttggatat taataacgac
     2161 ggcggtcaga atcaaagtca ggtctatcgt taaaattttt cttccagaaa ttagtgattg
     2221 accaagacgt tcctaaacct ccccaactac cacctgggat aacggcatta tacccaagtt
     2281 cccctccata aactgtctcc aactcagctt ctgtcaattc cattgtttct gcaaattgta
     2341 aatttaacat cttttacact ccttcaatta tcttcatttg taaaccactt ctgcgaccta
     2401 ggatttgctt caaatgtttt acaaggacag tataacacgg aaattggctt attttagaaa
     2461 atcgcatatt tgatattttt tcttatagaa atttcagatt tgcgattttg gtagatttga
     2521 ttatttccct ggtataataa agttattact aatgaggagg gaagtaatat gaagaaacaa
     2581 gttttaacat tattgacgat cgttgctgat attattatct ttttcccatt tctaactaat
     2641 ctataagttc tttatattgc tgaaaacgca attcaaaaag ggatgttaat tgtggatttt
     2701 ctaatacctg cagagattgg gtaaagcgtt caatctcttt ttgattgctt ccctttgttt
     2761 gaagaaagac actcatcttc tttaaaaatt gccacgatac tttttcaaaa acatcgtacg
     2821 gacgcaacat gctctccaac tcggcttcga agattgggat gtataagaaa agttttcgct
     2881 ccatgagttc tgataagata tttaagagtc cttgcttcat atacaatcga ttgtgtacta
     2941 actctttaaa ttccttggat ttttcgagta aggaggttga taaaaagatc agatcttgat
     3001 tgctcaagaa gggcatagta ttgcaaaaaa gatagagttc aaaccaggtc caagactcaa
     3061 tagcgtagag gtaggtagtc aaaaactcgc tatcctcctc tgttagcggg tatcttttat
     3121 ctaaggaatg gagtgcattt ttaatcacaa tggcattcaa acgacgatag gtctgcgcca
     3181 tctgttcttg atcgacttcc tccaatagct gctctaaagc agctatatcc tgatgggcaa
     3241 agcgatccac aacctttcga ccgattcgca tatgtggaga ttcttgatag ttgttgagct
     3301 tgtgcccaaa ctcatcaaaa ttcatattga tcccttggat ggctaggatc agcttgtctg
     3361 cagacagcat agactgtcct agttcaaact tggacaactg agaggctgtt agtccagcac
     3421 aagccacatc tgactgcttg agctttctag ccaagcgcaa ttccttgtaa aattccccca
     3481 gttccatttt ttcaatcatc ctaccacctc ctagcttttg catattatat cattatttgt
     3541 gttcatttgt caaaacattc tgacactttg gtgattgaaa aagccagcct taagctgact
     3601 ctaaaaggac cgagccttgt acaatacaga actcaatcct cgttctaaat agaatgtcta
     3661 acttttttgg gcagtacacg agcttgggga acagccactg gaacgatgag gtgtgagctc
     3721 aaaatatcct ccagttatgt ttttcctaat agtataccgg aagagtgaaa ggattttata
     3781 atggagcagt tacaaagaac ctactttcta ttaaacagta tactatgaaa atgtgaaaat
     3841 ttaacatttt tttgt
//
LOCUS       DAVLMQ010000104         3796 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000104 DAVLMQ010000000
VERSION     DAVLMQ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3796
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.105"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(194..727)
                     /locus_tag="VXF95_002124"
     CDS             complement(194..727)
                     /locus_tag="VXF95_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HEV1082597.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(816..1592)
                     /gene="recX"
                     /locus_tag="VXF95_002125"
     CDS             complement(816..1592)
                     /gene="recX"
                     /locus_tag="VXF95_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HEV1082598.1"
                     /translation="MKITKLEKKKRLYLMELDNVDKCYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDENIVSQVIANLKEDKW
                     INDGQYAYTIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPARALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYTKYARKYEGYELKQRLTQVLARKGYDFSDIASVLREYL"
     gene            complement(1602..2378)
                     /locus_tag="VXF95_002126"
     CDS             complement(1602..2378)
                     /locus_tag="VXF95_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HEV1082599.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQEAKITSWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     KLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            2435..3790
                     /gene="rlmD"
                     /locus_tag="VXF95_002127"
     CDS             2435..3790
                     /gene="rlmD"
                     /locus_tag="VXF95_002127"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HEV1082600.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRPTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKEDHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT         1197 a          674 c          704 g         1221 t
ORIGIN      
        1 acaaggaata aagacattaa aaaataacag tatatctatt tgttttatat attttacgaa
       61 ttctgcataa atttctttct agtaatgtgt tgtaactctg ctataatgga tttattcctt
      121 tttgtgttta cacaatttat tttatactac caaaaaaaca aggtcaggat tttgttcctg
      181 acctttgaca actttaccga ttctttagtt ctacatagcg cttgtaccaa atgtttacat
      241 aggcttctga gaaaggacca cgtccattgt taatccaatc aacaagaatt ttgacatgtt
      301 cttttaaaat atagtccaag tcatcagaat aattcatttt gcgtttgtga cgctcgtatt
      361 cttcaacgtc caagagacgt ttttccccat ctgtaaaaat tttaacatcc aaatcgtaat
      421 caatatactt cagtgcttct tcatccagat agtaggggct agccatattg caatagtaag
      481 aagttccatt atcacgaatc atggcaatga tattaaacca atatttcttg tgaaagtaaa
      541 caatagccgg ttctcgagtg acccaacgac gaccatcact ttcggtaaca agtgtatgat
      601 cgttgacacc aataatggcg ttttctgttg tttttagtac catggtgtcc cgccaagttc
      661 ggtggagact cccatcatgc ttataacttt gaattgtaat aaagtcgcct tcttttggaa
      721 gcttcataac taaccaactt tctacaattt ataagtttat catttactat tgtaccataa
      781 aattacctaa aatctgtgaa tttcacttgg aaatattaaa gatattctct aagaacgctt
      841 gctatatccg aaaaatcgta gccctttcgt gctaaaactt gagttaaacg ctgcttcagt
      901 tcgtatcctt catactttcg ggcatactta gtatattgct tatcaagttc cttgaagatg
      961 agttcctgag tcgtttcttg gtcaacttgg ctatctaagt cgtcaaaggc aattttagca
     1021 tcagaataag agaagccctt gttagtcaag ttctggataa tcttatcttg cagggcacga
     1081 gctggaagtt ttccctcata ttttttcaat agtttattag ctacacgttg agcaacttca
     1141 gaaaaatcaa attctttcaa gttctcttct atagtagatt ttgaaatccc tttttgagct
     1201 agtttctgag tcagcacata aggacccttg tctcctgaaa gttgattggt attgatgata
     1261 gtataagcgt actgaccatc attaatccac ttatcttctt taagattagc aataacttga
     1321 gaaacgatgt tttcatcaat atcgtatttt ttcagatatt ctctgacttc tttttcagtg
     1381 cgtgctttaa aggataagtg gtagagggcc agattcttac cataagaaaa ctgggcaaaa
     1441 tcctgaatct cggtcagttc ctctttacta atgaccttat ctctcgataa cataaaacga
     1501 acaattgtgt cttcggtgat atagcatttg tcgacattat caagctccat cagatagagt
     1561 ctttttttct tttcaagttt tgtgattttc ataatttcct ttcatctaaa tgcttcgaaa
     1621 gctgcaacaa gtcggagttt atccatattt acatattctc taccgtaata gtcgagaaat
     1681 aattcagcat acgtagcatc ttgtaggttg taatgaaggg accaaattgc ccaaaagagg
     1741 tcgatatgtc ggtcactaaa accagccaat cccaagtcaa taaagcaaga aaaatgagag
     1801 gcatccttca agatgaaatt tggcaggcag gcatctccat gaataaaagc atcagctttg
     1861 agaatgtaac ctttctcttg tatcagttgg taagcttctt cacgactgtg aatgtgaaat
     1921 tgaggcagaa gagtcttgtt ataaaaagtc cccttctgat agttttttaa ggctttttct
     1981 ttataacgct tcagatgatt ttccgacgga aaagattgtg gtttaagact gtgaagtttg
     2041 tttaatgctt gagccagggt ttgacagagt ttttcgggtt gatttaaaaa agcgagagcg
     2101 ttgctgccaa tggcttcttt agtcagaagg aagtccttat ttgctgataa ataggtaatc
     2161 actggagttc ccaatccttc agtttcgaac caacttgtaa tcttagcttc ttgagctaat
     2221 ctgccttttt gatctatttt taaatagtaa cctgaatcta tatataggac agttgcactt
     2281 gaatgagaag aactatcaga gagattagct cccttgatat agcttcgtaa ttgttcaggg
     2341 aaatctagta tactaaagcg aggtgttttt gaattcatgc ttttattgta acatattctt
     2401 aaatatctta gaaactccat ggtataatag acatatgaat ctgaaagtga aacaaaaaat
     2461 accattaaaa atcaagcgca tgggaattaa cggtgaggga atcggctttt accaaaaaac
     2521 attagtcttt gtaccaggag ctctcaaagg cgaagatatc tattgtcaga ttacttctat
     2581 tagacgcaac tttgttgaag caaaattact gaaggtcaac aagaagtcta aatttcgaat
     2641 tgtgccatct tgtactattt ataatgaatg cggaggctgc caaatcatgc acctgcatta
     2701 tgataagcag ctggagttca agacggactt acttcatcaa gcgctgaaaa aatttgctcc
     2761 tgcaggatat gaaaattatg aaattcgtcc aactattgga atgcaggaac caaaatatta
     2821 cagagctaag ttacaatttc agactcgaaa atttaaaaat caggtcaagg cgggcttata
     2881 tgcacaaaac tctcactatt tagtagagtt gaaagactgc ctggtacaag ataaggaaac
     2941 ccaagtgatt gctaatcgct tagcagaatt acttacttat caccagattc caatcacgga
     3001 tgagagaaaa gttctaggtg tccgtactat tatggtccga cgcgcgagaa agaccggaca
     3061 ggttcagatt attattgtta caaaccgcca gcttaattta actcaattgg taaaagagtt
     3121 ggttaaagat ttcccagaag ttgtgacagt agctgttaat acaaatacag ctaaaaccag
     3181 tgagatatat ggtgaaaaga cagagattat ctgggggcaa gagagtattc aagaaggtgt
     3241 actcaattat gaattttcac tatcccctcg agctttttat caactaaatc ctgagcaaac
     3301 agaagtcctc tatagcgaag cagtaaaagc gctggatgtt gataaagaag accatttgat
     3361 tgacgcttat tgtggagttg gaacgattgg atttgccttt gcaaagaaag taaaaacact
     3421 cagaggtatg gatattattc cagaagctat tgaagatgcc aagcgaaatg ctaaaagaat
     3481 gggatttgac aatactcatt atgaagctgg aacggcagaa gagattattc ctcgttggta
     3541 caaggaaggc taccgagcag atgctttgat tgttgaccca ccacgtacag gtctggatga
     3601 taagttatta gatactattc ttacttatgt accagaaaaa atggtttata tttcttgtaa
     3661 tgtttcgacc ttggctcgtg atttggtacg cttagtagaa gtctatgatc ttcattatat
     3721 ccagtcggtc gatatgttcc cacatacagc tcgaactgaa gctgttgtaa aattaataaa
     3781 aaaagtttaa aaaagg
//
LOCUS       DAVLMQ010000105         3762 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000105 DAVLMQ010000000
VERSION     DAVLMQ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3762)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3762)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3762
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.106"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            62..280
                     /gene="nrdH"
                     /locus_tag="VXF95_002128"
     CDS             62..280
                     /gene="nrdH"
                     /locus_tag="VXF95_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HEV1082601.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            361..2520
                     /gene="nrdE"
                     /locus_tag="VXF95_002129"
     CDS             361..2520
                     /gene="nrdE"
                     /locus_tag="VXF95_002129"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HEV1082602.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGECYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            2708..3670
                     /gene="nrdF"
                     /locus_tag="VXF95_002130"
     CDS             2708..3670
                     /gene="nrdF"
                     /locus_tag="VXF95_002130"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HEV1082603.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
BASE COUNT         1162 a          811 c          705 g         1084 t
ORIGIN      
        1 tgacaaaatt ttattttctg atatactaag atagtattaa attttgaaga ggagttacac
       61 aatggtaacc gtttattcta aaaacaattg tgtccaatgt aaaatgacca agcgtttctt
      121 ggacagtaat aatgtctctt atcgtgaaat caatcttgat gagcaacctg agtacgtcga
      181 tcaagttaaa gagctcggtt ttagcgcagc tcctgttatc caaacaccaa ctgaagtctt
      241 ttcaggtttc caaccaggaa aactgaaaca attagcataa tcttagtaca tcatccagaa
      301 gaaactactt ttagggctaa cttagaagcc tttcttttgt aattagataa gggaaatttt
      361 atgggattaa aacatcttga agacgtgact tacttccgtc ttaataacga aattaaccgt
      421 cctgttaatg gacaaatcat gcttcataaa gataaggaag ccttggatgc tttctttaaa
      481 gaaaatgtag ttccaaacac tatggttttt gattcaatca aagacaaaat caattacctc
      541 attgaacaca actacatcga aacagccttt atcaagaaat accgtccaga gttcttggaa
      601 gaattggctc aatttatcaa agaccaaaac ttccaattca agtcattcat ggcagcttat
      661 aaattttaca atcaatatgc cttaaagact aatgacggtg aatgctatct tgaaaatatg
      721 gaagaccgtg tcttcttcaa cgccctttat ttcgctgatg ggaatgaagc tgttgcaatc
      781 gatattgcca atgaaatcat ccaccaacgc taccaacctg ctactccttc cttcttgaat
      841 gctggacgtg ctcgtcgtgg ggagttggta tcttgtttcc taatccaagt gacggatgat
      901 atgaactcta tcgggcgttc tatcaactca gctcttcaac tttcacgtat tggtggtggt
      961 gtgggaatta ccctcagcaa ccttcgtgaa gctggtgcac ctatcaaagg ctatgaagga
     1021 gctgcttcag gtgtcgttcc tgttatgaag ctttttgaag acagcttctc ttactccaac
     1081 caattggggc aacgtcaagg tgctggtgtt gtctacctca acgtctttca cccagatatc
     1141 atcgctttcc tttcaactaa gaaagaaaac gctgatgaaa aagtacgtgt caagactcta
     1201 tcacttggtg ttgtagtacc tgataaattc tacgaattgg ctcgtaaaaa tgaagaaatg
     1261 tacctcttca gcccttactc tgtagaaaaa gaatacggtg tgccattcaa ttacatcgac
     1321 attactgaaa aatacgatga attggtcgca aatccaaata ttcgcaagac aaaaatcaag
     1381 gcgcgggatt tggaaactga aatctctaaa ttgcaacaag agtctggcta tccttatgta
     1441 gtcaacatcg atacggctaa ccgtgcaaat cctgttgatg gaaagattat catgagtaac
     1501 ttgtgttctg agattcttca agttcaagaa ccaagcttga tcaacgatgc tcaagaattc
     1561 cttcaaatgg gaacagatgt ttcatgtaac ctgggttcaa ccaacgtggt taacatgatg
     1621 acttcacctg attttggtcg ttctatccgt gctatggttc gtgcccttac tttcgttaca
     1681 gatagttcac atatcgtagc tgtaccaacg attgaccatg gaaatagcca agcccacacc
     1741 tttggtctcg gtgccatggg actgcacagc taccttgccc aacaactcat tgaatatggt
     1801 tcacctgagt ctgttgaatt tacaagcatc tactttatgc ttatgaacta ctggaccttg
     1861 gtagagtcaa acaatattgc acgtgaacgt ggtattacct tccacaactt tgaaaaatca
     1921 gactatgcta acggaagtta ctttgacaag tatgtaactg gtgaatttgt tccaacatca
     1981 gaccgtgtta aagaactctt caaaaatgtc tttatccctg gtgttgctga ttgggctgaa
     2041 cttcgcgaca aggttcaaga agatggtctt taccaccaaa atcgccttgc tgtagcgcca
     2101 aatggttcta tcagctatat caacgacgtt tctgcttcta tccacccgat tacgcaacgt
     2161 atcgaagaac gccaagagaa gaaaattggt aaaatctact accctgctgc tggcttgtct
     2221 acagaaacca ttccttacta cacttctgcc tacgatatgg atatgcgtaa agtcatcgat
     2281 gtttacgctg ctgcgactga acacgtggat caaggacttt cactcaccct cttcatgcgc
     2341 agtgacattc caaaaggcct ttacgaatgg aagagggaaa ataaacaaac gacacgtgac
     2401 ttgtccatcc ttcgtaacta tgcctttaac aagggaatca agtctatcta ctacgtccgt
     2461 acctttacag atgacggtgg agaagtcggc gccaaccaat gtgaaagctg tgtgatttag
     2521 tttctagcat agaaacacta tttttcccta agcagcactg ataaaatcaa atctactatg
     2581 tcataacata atttatgtaa cattttaaaa gtcgggcttc cgactttttg tgcgatactc
     2641 ctatagaatt atggtaaagt agaaataatt gtgagttcgc aatactaaac acagaaagag
     2701 attttaaatg gaaacttact acaaagccat taactggaat gccatcgaag atgtcatcga
     2761 caaatcaact tgggaaaaac tgacggagca attttggctc gatacacgta ttcccttatc
     2821 aaacgacttg gatgactgga gaaagctatc taacaaagag aaagacttgg tcggaaaagt
     2881 ttttggtggt ttaacccttc ttgacactat gcaatctgaa actggggttc aagcccttcg
     2941 cgcagacatc cgtacaccac atgaggaagc tgttttcaat aacatccaat ttatggaatc
     3001 tgtccacgct aaatcttact catcaatctt ttctaccttg aatactaagg ctgagattga
     3061 agaaattttc gaatggacca ataccaatcc ttacctacaa aagaaggctg agattgtcaa
     3121 cgaaatctac ctaaacggca gcccacttga aaagaaagtt gccagcgtct tcctcgaaac
     3181 cttcctcttc tactctggtt tcttcactcc cctctactat ctcggtaaca acaaactagc
     3241 caacgttgca gaaatcatta aattgattat tcgtgacgag tctgttcacg gaacctacat
     3301 tggttacaaa ttccaacttg gtttcaatga attgcctgaa gaagagcaag aaaaactcaa
     3361 agaatggatg tacgacctac tctatactct ttatgaaaat gaagaaggct acacagagag
     3421 tctttatgac ggtgttggtt ggactgaaga ggttaaaacc ttccttcgct acaatgccaa
     3481 taaagctctc atgaacatgg gacaagatcc acttttccca gattcagctg aagatgtcaa
     3541 cccaatcgtt atgaacggta tttcaacagg aacttccaac catgacttct tctctcaagt
     3601 cggaaatggt taccttcttg gcgaagttga agccatgcaa gatgatgact acaactacgg
     3661 tttggactaa tactcttcga aaatcaaatt caaaccacgt cagcttcgcc ttgccgtact
     3721 caagtacagc ctgcggctag cttcctagtt tgctctttga tt
//
LOCUS       DAVLMQ010000106         3573 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000106 DAVLMQ010000000
VERSION     DAVLMQ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3573
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.107"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..832
                     /locus_tag="VXF95_002131"
                     /pseudo
     CDS             1..832
                     /locus_tag="VXF95_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            864..1777
                     /locus_tag="VXF95_002132"
                     /pseudo
     CDS             864..1777
                     /locus_tag="VXF95_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833783.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            1787..3403
                     /locus_tag="VXF95_002133"
     CDS             1787..3403
                     /locus_tag="VXF95_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082604.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTSQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
BASE COUNT         1304 a          376 c          673 g         1220 t
ORIGIN      
        1 tcaactaatt attttttata tatgttaaaa aaacttgaca agaatggatt tggaaaggtt
       61 aagacagtga taacatgcca tggatgggtt gaatataact taaaaaagaa attcttgact
      121 tattttgatt tttggacata ttctatggga gatgctttta tttgtgtatc tgaaactatg
      181 aaaaaaagat tggagagtat aataaaaaaa taagaagata gttgcaataa ataacggaat
      241 taatgtatca aatagcgatt tagatgtagt aggtgttcaa gactttaaaa aagaattttg
      301 tattccaaat aacaaaaaaa tcatttgtta tttggaaggt tggatccaga aaaaaggccg
      361 gatagattcc ttgaatttgc agaaaaatta tttttagtca gagaagatgt gatttttatt
      421 atggctggaa atggtagtat gtgggctgct ttgaaagaaa aaatttgcca tttgaaatgt
      481 agagataatt tcaggttact tggtgaaatc tatccagcta ctatagttta ccaaatatcg
      541 gatttattgt atattccttc tgatacagaa ggaataccta tgtgtgtttt agagtcaatg
      601 tcacaaggaa ctccggtttt agctagtaat gttggcgggt taagtgaaat tattgaacat
      661 agggttgatg gatttttatt tgagaaggaa gatgttgagg gagtgtgtgc ttgtgctaat
      721 tttttactca atgattctga gtatttgaaa tatataggtg agaatagtaa atcaaaaata
      781 agaaaacatg agagtatatg atgaattatt agagaagagt agtcatggat aggaatatag
      841 attaagaatt agtaagtatt ataataccaa cacataatag gtatgaatct ctgattagag
      901 ctgtgaaaag ttgtttacat caaagttata aaaatatcga agttataatt attgatgata
      961 attatagtaa tgtaaattta agaaataaaa ttatccatca atttggctat accaatcata
     1021 gaattaagtt aattttaagt aatgaagatt taggtgcaac taatgccaga aacataggta
     1081 tcaaaaattc tagaggtaag tatatatcat ttttagacga tgatgatgaa tatatgccag
     1141 atcgaatttt taagttgatg gcttgtttta aaaagagtag aatgaagaat ttagctttag
     1201 tttatagtta tggaataata atttatccaa atggtacacg agaagaggag aagaccgatt
     1261 ttgttggaaa tcccttgttt gttcaaatgg ttcacaatat agcaggtacg tcattttggt
     1321 tgtgtaaaaa agaggtgcta gaattaatta atggttttga gaaaatagat tcacatcagg
     1381 acggtgttgt tttattaaaa ctacttgctc aaggatacca aattgatata gtgcgagaat
     1441 tcttggtgaa ttactacgct cacagtaaag aaaacggtat cactggagtg acacaaaaaa
     1501 caattaatgc agatgaagaa tattataatt actgtaggaa atattttaat ttattgagtt
     1561 tcaacgagag aatattggtt acaaagaaat attattcttt aaacataaag cggttactat
     1621 taataggaga caaatgcaag gctttaaaag taatcaagaa ggcaagagaa gaaaaaattt
     1681 ttaacgaatt tcttttttga aatatatgtt attatatcat tttggctttt tctattgtat
     1741 atatgacaac tatgttcaat taaaatttag aaagtgagaa actattgtgt atactattat
     1801 aaaatcaaat ataaaaaaat ttagtttatt aacgatattt attgttgctg gtcaattatt
     1861 gctaatttat gcagcaacta ttaatgctct ggtgttgaat gaattaattg cgatgaattt
     1921 agagcggttt ttgaaattgt caatctacca aatgattgtc tggtgtggga taatattcct
     1981 tgactgggta gtgaaaaatt atcaggttga agtgatccaa gagtttaatc tagagattcg
     2041 aaatagagtt gccacagaca tctctaactc tacctatcaa gaatttcata gtaaatcatc
     2101 aggaacatat ctttcgtggc taaataatga tgttcagact ttaaatgatc aggcttttaa
     2161 acaacttttt ttagtaataa aaggaatttc tggtactata tttgcagttg tgactcttaa
     2221 tcactatcat tggtcattga ctgtagccac cttgttttca ttaatgatta tgctacttgt
     2281 accaaaaatc tttgcatcga aaatgcgaga agttagtcta aatttaacta gccaaaatga
     2341 agctttttta aaatctagtg agactatatt gaatggattt gatgtgttag cgtccttgaa
     2401 tcttttatat gtattgccta agaaaattaa agaagcagga attttattaa agatggttat
     2461 acaaagaaag acaactgtag aaacgttagc aggcgctatt agcttctttc tcaatatttt
     2521 ttttcagata tctctcgttt ttttaacagg ctatcttgca ataaaaggaa tagtgaaaat
     2581 tggtactatt gaagcaatag gagcactaac aggtgttatt tttacagcgc taggtgaatt
     2641 aggaggtcaa ttatcctcta ttattggtac gaagcctatt tttttaaaat tgtattcaat
     2701 taatccaatt gagtcaaata aaatgaatga tatcgaacca aatgaggtga atagagattt
     2761 tccgttatat gaagcaaaaa atatttgcta taagtatgga gataaagaaa tattaaaaaa
     2821 cttaaatttt tgttttcaac gtaatgaaaa gtatttaatt ttaggtgaaa gtggaagcgg
     2881 gaaatctaca ttattaaaat tattgaatgg ctttttgaga gattatagtg gagaattgcg
     2941 attctgcggg gatgatataa aaaaaacctc ctatttaaat atggtttcga atgttctata
     3001 tgtagatcaa aaagcttatt tgtttgaagg tacgattaga gataatattt tattggaaga
     3061 aaattatact gatgaagaaa tactacagtc tttagagcaa gttggtttga gtgtaaaaga
     3121 ttttcctaat aacattttag attattatgt tggtgatgat gggagattac tgtcaggagg
     3181 gcagaaacaa aaaattactt tagctagagg gctaattaga aataagaaaa tagtattaat
     3241 tgacgaggga acttctgcta tcgataggag aacttcgtta gcgattgaac gtaagatatt
     3301 agatagagag gatttgactg tcattattgt tacccatgct ccgcatccgg aacttaaaca
     3361 atattttact aagatatatc aatttccaaa ggattttatt taagaatata ggggagggaa
     3421 acatgagatt ctattgtgaa gcttatgagg taattactga agagaaaaaa gtatcatttt
     3481 tttatgtaga tgaaaaaccc ttaaggtatc tgttatttga ctatatattt ctactagttc
     3541 tagctaaaaa aaaatatccc aatcttatga act
//
LOCUS       DAVLMQ010000107         3506 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000107 DAVLMQ010000000
VERSION     DAVLMQ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3506
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.108"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            78..1427
                     /locus_tag="VXF95_002134"
     CDS             78..1427
                     /locus_tag="VXF95_002134"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HEV1082605.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            1551..3011
                     /locus_tag="VXF95_002135"
     CDS             1551..3011
                     /locus_tag="VXF95_002135"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HEV1082606.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVVIDDHDMQISHVIRGD
                     DHIANTPKQLMVYEALGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDEFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            3025..3459
                     /locus_tag="VXF95_002136"
     CDS             3025..3459
                     /locus_tag="VXF95_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HEV1082607.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAGDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     EFNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
BASE COUNT         1171 a          678 c          737 g          920 t
ORIGIN      
        1 gagaaattcg acaaaaaaac ttgaaaaaaa cgaaggtaag cgttatgata gaaaagaaga
       61 aatattggag gaagaacatg tcacatatta aatttgatta ttcaaaagtt ttagacaaat
      121 ttgttgcacc acatgaagtg gaatacatgc aatcacaagt aacagcagca gatgaattga
      181 tccgtaaagg aactggtgct ggtagcgact tcttgggatg gttggacctt cctgaaaaat
      241 acgaccgcga agaatttgac cgcatcttga aagctgctga gcaaatcaag tcagacagcg
      301 atgttttggt tgtgatcggt attggtggat cttaccttgg tgcaaaagca gcaatcgact
      361 tcttgaatca ccattttgct aacttgcaaa caaaagaaga acgcaaagct ccacaaatcc
      421 tttacgcagg aaactcaatc tcatctactt accttgctga cttggtagag tatgttgcag
      481 acaaagactt ctcagtaaac gtaatttcta aatcaggtac aacaactgaa ccagcgattg
      541 ctttccgtgt ctttaaagaa ctcttggtta agaaatacgg tcaagaagaa gctaacaaac
      601 gtatctatgc aacaactgac cgccaaaagg gtgctgttaa ggttgaagca gacgctaacg
      661 gttgggaaac atttgttgtt ccagatgata tcggtggacg cttctcagta ttgacagccg
      721 ttggtttgct tccaatcgca gcatcaggag ctgacatcaa agctcttatg gaaggtgcga
      781 atgcagctcg caaagactac acttcagaca aaatctctga aaacgaagct taccaatacg
      841 cagccgttcg taacatcctt tatcgtaaag gctatgcaac tgagatcttg gtaaactatg
      901 agccatcact tcaatacttc tcagaatggt ggaaacaatt ggctggtgaa tcagaaggaa
      961 aagaccaaaa aggtatctac ccaacttcag ccaacttctc aactgacttg cactcacttg
     1021 gtcaatttat ccaagaagga actcgtatca tgtttgaaac agttgtccgt gttgacaaac
     1081 ctcgtaaaaa cgtgcttatt cctactttgg aagaagacct tgacggactt ggttaccttc
     1141 aaggaaaaga cgttgacttt gtaaacaaaa aagcaactga cggtgttctt cttgcccaca
     1201 cagatggtga tgtaccaaac atgtatgtga ctcttccaga gcaagacgct ttcactcttg
     1261 gttacactat atacttcttc gaattggcaa ttgccctttc aggttacttg aatgctatca
     1321 acccatttga ccaaccaggt gttgaagctt ataaacgtaa catgtttgcc cttcttggaa
     1381 aaccaggatt tgaagaattg agcaaagaac ttaacgcacg tctataatag aagaaaagag
     1441 tggtttgccc actcttttta ctctctttat ccatagaaat tggactcagc caagacttgt
     1501 gatataatat agaaagcaaa aaggcagacg cctagataat aggagaaatt atgtcaaaag
     1561 atatccgcgt acgttacgca ccaagtccaa caggactact acacatcgga aatgctcgta
     1621 cagcattgtt taattacttg tatgcgcgcc atcatggtgg aacatttctc atccgtatcg
     1681 aagatactga ccgtaaacgc catgtcgagg atggtgaacg ttcacaactt gaaaaccttc
     1741 gctggttagg catggattgg gatgaaagtc cagaatcaca tgagaattat cgccagtctg
     1801 agcgtttaga cttgtatcaa aaatacattg accaactatt agctgaagga aaagcctata
     1861 aatcttacgt tacagaagaa gagttggcag ctgaacgcga acgccaagaa gtagctggcg
     1921 aaacaccacg ctacatcaat gaataccttg gtatgagtga agaagaaaaa gcagcttaca
     1981 tcgcagaacg tgaagcagca gggatcatcc caactgttcg tttggctgtc aatgagtcag
     2041 gtatctacaa gtggcatgat atggtcaaag gcgatatcga atttgaaggt ggcaatatcg
     2101 gtggtgactg ggttatccaa aagaaagacg gttacccaac ttacaacttt gccgttgtta
     2161 tcgatgacca cgatatgcaa atctctcatg ttatccgtgg agatgaccat attgctaata
     2221 caccaaaaca gcttatggtc tatgaagctc ttggttggga agctccagag ttcggtcaca
     2281 tgaccttgat tatcaactct gagactggta agaagttatc taaacgtgat actaatacac
     2341 ttcaatttat cgaagattac cgaaagaaag gttaccttcc agaagcagtc tttaacttta
     2401 ttgctcttct tggttggaac ccaggtggtg aagatgagat tttctctcgt gaagaactca
     2461 ttaaactttt tgatgaaaac cgcctcagca agtcaccagc agcctttgat cagaaaaaac
     2521 tagactggat gagcaatgat tatatcaaga atgcagacct tgaaaccatc tttgaaatgg
     2581 caaaaccatt cttagaggaa gcaggccgtt tgactgacaa ggctgaaaaa ttagttgagc
     2641 tctataaacc acaaatgaaa tcagtagatg agattatccc attgacagat cttttcttct
     2701 cagatttccc agaattgaca gaagcagagc gcgaagtcat gacgggtgaa acagttccaa
     2761 cagttcttga agcattcaaa gcaaaacttg aagcgatgac agatgatgaa tttgtgacag
     2821 aaaatatctt cccacaaatt aaagcagtcc aaaaagaaac aggtattaaa gggaaaaatc
     2881 ttttcatgcc tattcgtatc gcagtttcag gcgaaatgca tgggccagaa ttaccagata
     2941 caattttctt gcttggacgt gaaaaatcaa ttcagcatat cgaaaacatg ctaaaagaaa
     3001 tctctaaata aagaggatac aataatggac atctgggaaa agatgtacga agaagcacag
     3061 aaactataca atccacatga agtatcagac tttgtttatg ccaatcatgt tgtagctgca
     3121 gtagaagcag gagatggaca aatatttaca ggattctgta tggagggaac ctgtggtgtt
     3181 ttccatctct gcgcagaacg ggcggccctc ttcaatatgt accaattttc aggacaaact
     3241 aaggttaaga aagtattagc ctttcgagac aaaccacctt atggtggaag ttcagccatg
     3301 ccttgcggtg cttgtagaga attcctttta gagtttaatg ctgaaaataa agatgcagaa
     3361 ttcatgatgg actataatat aagaaaaaca gttaaagtcg cagaactaat cccttattgg
     3421 tggggagaag aacgtgcttc taagtttaat gagcgataga agagtcagta taattctggc
     3481 tttttttact ataagttgaa aaaata
//
LOCUS       DAVLMQ010000108         3499 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000108 DAVLMQ010000000
VERSION     DAVLMQ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.109"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(246..857)
                     /gene="rpsD"
                     /locus_tag="VXF95_002137"
     CDS             complement(246..857)
                     /gene="rpsD"
                     /locus_tag="VXF95_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HEV1082608.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            complement(1052..2104)
                     /locus_tag="VXF95_002138"
     CDS             complement(1052..2104)
                     /locus_tag="VXF95_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HEV1082609.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            complement(2101..2799)
                     /locus_tag="VXF95_002139"
     CDS             complement(2101..2799)
                     /locus_tag="VXF95_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HEV1082610.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            complement(2966..>3499)
                     /locus_tag="VXF95_002140"
     CDS             complement(2966..>3499)
                     /locus_tag="VXF95_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HEV1082611.1"
                     /translation="ENVKTKGQYFYQLALDGNVAGKEKQALIDQFRANGTQTYSATVN
                     VYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVTPMNHNHATGTT
                     DSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQTSMASIGFLGLA
                     LAGLLGGLGLKNKKEEN"
BASE COUNT          966 a          780 c          670 g         1083 t
ORIGIN      
        1 ttctgttata ctacctgttc gctcacaata agagagaact tttttacgaa aatctattga
       61 atatgccata aaagattata ccacattgtg tactattttt ggttcatttt actatatcac
      121 tttggactat atcggtctag ttatgtctaa acgattatag ctggatacta agagaaatca
      181 aaaaagcact aagggagaac gtcccaaagt gcttaatatc aaagcctatc ttattcaata
      241 aaatattaca acattttgtt gtagaattca acgacaagtg cttcgttgat ttctgggttg
      301 atttcgtcgc gttctggcaa gcgagtcaat gaaccttcca atttttcagc gtcgaatgat
      361 acgaatgctg gacgtccaag agtagcttct actgcttcaa ggattgctgg aactttcaat
      421 gatttttcac gaactgagat cacttgacct ggagttacgc ggtatgatgg gatatcaacg
      481 cgtttcccgt caacaaggat gtgaccgtgg tttacgaatt gacgagcttg acgacgagta
      541 gtcgcgagac caagacggta aacaacgtta tccaaacgac gttccaaaag aagcataaag
      601 ttgaaaccta ggattccgcc tttgattttt gtagcttgta cgaacaagtt acggaattgt
      661 ttttcaccta caccgtaagt gaaacgaagt ttttgttttt cagccaattg caaaccgtat
      721 tctgacaatt tagaacggtt gtttggtccg tgttgtcctg gtacgtagtt acgacgtgcc
      781 aattctttac ctgtacctgt aagtgaaagg ccaaggcgac gagcttgttt ccaagatggt
      841 cctgtataac gtgacatatg aatgtcctcc tgatataaat aatatttcgg tggaaatagt
      901 cacttagaaa gccctgattc gtgcagatgc ccttcgccta aacagccaag gttacttgtc
      961 ataagacacc tgttgacgag cttcatgctt tcctgctgat atttcacaca aaatctattc
     1021 taccatgaat agctggattt gtaaaggggt tttaggcttt attttcacta ccagagaggt
     1081 tgagaacgag ggtaaaggta cttcctagac cgtactggct gctgactgtg atttccccac
     1141 ccaattgatg ggccaattca cgcgcaatcg caagtcctaa tccatgacca cctgtcttca
     1201 tgttacgcga agtttcgaca cgataaagac gtttgaaaat attttccaaa tcctctgggg
     1261 caataccctg cccttcatcg gtcacactga ttgaaagctg gtccttctcc agcttagcca
     1321 ccacttccag cttggttcct ggagcagaat atttaaaagc gttatcgacc agattcacca
     1381 agatacgaga aagcttagca taatctccct caatccgggc agactctggg attacctgca
     1441 agtggacatc tcttctctcc tgctcaatca aaaactgaaa ttcactcatg cactcaatta
     1501 agagcttgtc cagaaaaata ctgtctttac tggtagtttc cacctgattt ctagctgtgt
     1561 ttagggtcaa aaaattcaac tcctcaacca gtttattgag cctctccgtc tggcgtccaa
     1621 tggttgctag ataatgagct tgctccgact ccttgataat cccatccaaa atcccttcta
     1681 ccgtcgcttg aatcgaagtg ataggggtct taatatcatg cgacaactgg gcaatcatca
     1741 agcccttttc tcgttcgctt tcttccaagg aatcaaagct tacctgcaaa tcatgggaca
     1801 tctcattaaa agtttgccct aattgctgaa attctacagg accttgaacc tccaaatttg
     1861 aaggaaaatc cttggccgct acccgcttgg catgctcctt gagtttgccc aacgacgtaa
     1921 agactggcaa taggagaaag agactaatcc cagcaccgac aaggctggca acgatggtca
     1981 tcccaagcaa aaagtaaatc tcgcctttcg caatcagcat tttttgaaca gcccaaaaaa
     2041 caaccaaaat ggttaagagg gttgaaataa tatatccaac caaaatataa ctttttagtt
     2101 tcatgtttgt cctctcggtt tctctatctt atatcccaac ccccaaactg tcttaatagt
     2161 gggcgtttgg tcactactat attttgccag ctcctgtcga agagcatgga tatgcacatt
     2221 caaggtattg gtgtcatcca cgtagtcttc tttccagatc ttttcataga ggtctgtctt
     2281 ggagaaaact cgctctggat tgctagctaa aatccacagc aattcaaatg atttaacagt
     2341 taaatccagc atttcttctc ctatttgaac ttcatgacta ctatgattca tttttagatt
     2401 gccaagggaa atcagctctg tttcgccccc acgatgaagg cggcgcaaaa tattgtggac
     2461 acgcaaaacc agctcacgtg ggctaaaagg cttagcaata aaatcatctg ctcccaagct
     2521 caggccgtaa atcttgtcct gttcactggt cttagcagta ataaatagga aaggctgctc
     2581 tggtgataag tattgaacct cactgattaa atcataacca tccatccgag gcatcatgac
     2641 atctgtgata atcaaatcaa tcggtttttt cttgaacagc tctagcgctt ccagtccatc
     2701 atgggctacc aagacctgat aacctgcctg aattaagtat ctctgatgaa tatctgtgat
     2761 ttctacctcg tcgtcaacga gtaaaattgt ctttcccatc tgtctctcct ttgataaaaa
     2821 cagtgctata ctgctttaag tataacacta tttttattgt tttacgatga ttttaatctg
     2881 ctattgaaag aaagtcctga ttgctgattg agttgttaaa ctaatcttag tcagcccact
     2941 atccatcatt tatttcctta gctgattagt tttcttcttt tttgtttttc aaacctagac
     3001 caccgagtaa acctgcaagc gcaagcccaa ggaaaccaat acttgccatt gatgtttgag
     3061 tctcaccagt atttggtagc atagctttat cctctgacat catcgtatca gacatcttgt
     3121 tagcagaagc agccatgttt tcacctgcca tcgtgttggt agaacttgtc atggtgtcag
     3181 caggcatgct atctgtagta cctgtagcat gattgtgatt catcggagtc acgccagaac
     3241 cagagttaga aggtgataat gaaccatttg ctgtgtctga tgtttcttta acatttatct
     3301 taatagtgac ttttttagtt gctacgatgt tgtccaagtc tggtttaccg tctttgttac
     3361 catagacatt gactgtagcg ctgtaagttt gagtaccgtt tgctcggaac tggtcaatga
     3421 gcgcttgttt ttctttgcca gctacatttc cgtccaaggc taattgatag aagtattgac
     3481 ctttggtctt cacgttttc
//
LOCUS       DAVLMQ010000109         3237 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000109 DAVLMQ010000000
VERSION     DAVLMQ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3237)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3237)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3237
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.110"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            24..1049
                     /locus_tag="VXF95_002141"
     CDS             24..1049
                     /locus_tag="VXF95_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HEV1082612.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGLSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIRIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            1039..2046
                     /locus_tag="VXF95_002142"
     CDS             1039..2046
                     /locus_tag="VXF95_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1082613.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            2046..3053
                     /locus_tag="VXF95_002143"
     CDS             2046..3053
                     /locus_tag="VXF95_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HEV1082614.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGVLLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            3053..>3237
                     /locus_tag="VXF95_002144"
     CDS             3053..>3237
                     /locus_tag="VXF95_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082615.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLL"
BASE COUNT         1112 a          457 c          567 g         1101 t
ORIGIN      
        1 tgaaatatgt tcaaggagtt tttatgaaaa acaaattttt tctaatagct attttagcta
       61 tgtgtatagt ttttagcgct tgttcttcta attctgttaa aaatgaagaa aatacttcta
      121 aagagcatgc gcctgataaa atagttttag atcatgcttt cggtcaaact atattagata
      181 aaaaacctga aagagttgca actattgctt ggggaaatca tgatgtagca ttagctttag
      241 gaatagttcc tgttggactt tcaaaagcaa attacggtgt aagtgctgat aaaggagttt
      301 taccatggac agaagaaaaa atcaaagaac taaatggtaa agctaaccta tttgacgatt
      361 tggatggact taactttgaa gcaatatcaa attctaaacc agatgttatc ttagcaggtt
      421 attctggtat aactaaagaa gattatgaca ctctatcaaa aattgctcct gtagcagcat
      481 acaaatctaa accttggcaa actttatgga gagatatgat tagaattgat tcaaaagcct
      541 taggtatgga aaaagaaggt gatgagttaa tcaaaaatac tgaagctcgt atatccaaag
      601 aattagaaaa acatccagaa atcaaaggaa aaatcaaagg aaaaaaagta ttatttacta
      661 tgattaatgc tgcagataca tcaaaattct ggatttatac tagcaaagat ccaagagcaa
      721 attatttaac agatttaggt ctagttttcc ctgaatcatt aaaagaattt gagagtgaag
      781 atagttttgc aaaggaaatt tctgcagaag aagcaaataa gataaatgat gctgatgtaa
      841 tcataactta tggtgatgat aaaactcttg aagctttaca aaaagatcct cttttaggta
      901 aaataaatgc aattaaaaat ggtgccgttg ctgtaattcc agataataca ccgttagcag
      961 cctcatgcac tccaacacca ctttcaataa actatactat tgaagaatat ctaaatcttt
     1021 taggaaatgc atgcaaaaat gcgaaataaa aaacaaataa acctaggcat aatttttgta
     1081 atctgcctag gtcttcttat tacaatattt ttgtcattaa agcttggaac aaaagaaatt
     1141 aatatcagag attttttagc agcttttgga atgggtaata caaatgatga ttttattaaa
     1201 tcaattatat ataaaagaat acctagaact atttttgcaa ttttagcagg ttctagtctt
     1261 gccataagcg gtgtattgat gcaatcagtt actagaaacc caatagctga tccaggtata
     1321 ctcggtataa acacaggagc aagtcttagt gtagtaattg gtctttcttt tttaggaatt
     1381 tcatcaagca taagccatat aagttttgca atcattggtg gcttagtaag tgcaattttt
     1441 gtatacgcga ttgctgtaag cggaaaagca ggccttaccc ctataaaact tgccttatca
     1501 ggaacttgtg ttagtatggc tttaagcagt tttgtaagtt ttttaatttt accgaataat
     1561 aacgtcttag acaaatttag attttggcaa ataggtagcc ttggagcagc tacattatct
     1621 tctatatcta cactactacc ttttataatt ttaggtcact tgatagctat atttatttca
     1681 tcagatttaa acgctttagc tatgggtgat gaaatggctg ttggtcttgg agttaatgtt
     1741 aataggataa gatcacttgc aataattgca agtgtgcttt tatgttcaag tattactgca
     1801 attggtggac ctattggctt cgtaggtctt atagttcctc acttttgtgg cttatttata
     1861 agcaaagata tacgcacaat gaccatttct tcatctttta taggtgcaga gctcttgctt
     1921 atatgtgata taatcggccg tatgttaggt aaaccaggtg aaattgaagt agggataatt
     1981 actgcaataa tcgggggtcc agtacttatt tatgtaacta tgaaaaatag aggggttaat
     2041 aactaatgca aaatttaatt ataggtattc aaaaaagaaa aaatagaata acactattct
     2101 cctcactatt tttattaata ataatcagtc tatcattttt cattttactt atcggagatg
     2161 aaagttattc tttttcaact ttgattaaag tcttaaatag tgaaactgtt cctggagcta
     2221 gtttttcgat tatggaaatt agattaccaa aattattagc aggaattata gctggctggt
     2281 cttttggatt ggcaggattt atctttcaaa ctatgttaag aaatcctctt gcaagtcctg
     2341 atataatcgg tgtcacaagt tcttcatcta ttgcagcggt cttttgcata ttggtattaa
     2401 aaacaaatag tttaactact ggaattattt caataacttg tggactaaca tcatctttaa
     2461 tattattttt actagctaaa aaagatggtt tttcagcagc aagactgata atattaggta
     2521 ttggttttca agctgtcaca agagcaggca cctcattttt attgttgaaa gtagcaagat
     2581 atgaattaca agaagttatg agatggctca gtggctcttt atcttttaca aagttagatg
     2641 acatacctct tgttctaata gtaagtatta ttgctactat attagtttta ttttttaata
     2701 aaagactaga aattattgaa cttggtgaag aaatagcaat cggacttggt gcaaatcccg
     2761 agctttcaag gcttgtttta attttttgcg ctgtatcttt aactgctttt tctacttcaa
     2821 ttacaggacc aatagcttgt atatcttttt tagctggtcc catagcctta aatattggca
     2881 agaaaagaag cccaatatta gctggattgg ttggagtttt actagttttg ttatcagaca
     2941 tattctctca aaatatttta ccagctagat atccagtagg tgttgtaact ggcttgttag
     3001 gttcaccata cttaatatat ttactaataa aaatgaacag gaggaatata taatgaaagg
     3061 tctgtggtca aataatctta cctgcggtta tgatgaaaaa ataatcttgg aaaatataaa
     3121 tataaaaata cctgaagaaa aaatatcagt tattattggg tcaaatggtt gtgggaaatc
     3181 aacactcatt aaaaccttgt ctcgacttat aaagccatta gagggagaag tattgct
//
LOCUS       DAVLMQ010000110         3050 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000110 DAVLMQ010000000
VERSION     DAVLMQ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 3050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3050
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.111"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..155
                     /locus_tag="VXF95_002145"
     CDS             <1..155
                     /locus_tag="VXF95_002145"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082616.1"
                     /translation="GFEVVDETDEVSSKHGFEVADETDEVSSKHGFEVADRTDEVSNI
                     YTVRRR"
     gene            complement(191..1132)
                     /locus_tag="VXF95_002146"
     CDS             complement(191..1132)
                     /locus_tag="VXF95_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HEV1082617.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINSLFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(1110..2873)
                     /gene="aspS"
                     /locus_tag="VXF95_002147"
     CDS             complement(1110..2873)
                     /gene="aspS"
                     /locus_tag="VXF95_002147"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HEV1082618.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRDLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEQEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVANATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EETAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSAEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          892 a          707 c          619 g          832 t
ORIGIN      
        1 atggttttga ggttgtagat gaaactgacg aagtcagctc aaaacatggt tttgaggttg
       61 cagatgaaac tgacgaagtc agctcaaaac atggttttga ggttgcagat agaactgacg
      121 aagtcagtaa catatatacg gtaaggcgac gctgacgtgg tttgaagaga ttttcgaaga
      181 ctattaatca ctaattatct atctcaacaa atcttcctag aatatgaaca ttttccgaga
      241 cagagacaaa ggagcttgga tccacttgtg tcataatctg tttaaattca ttaaactctg
      301 cacgtgtaat gacagtgatt aaaactgcct ttctctcgtg attataggtt ccttctgcat
      361 cgtggatcat ggttgctccg cggtgcaatt ttttatggat tttttcaatt accttctctg
      421 gatgatttgt cacaatcatg gcctgcatac gcttttgctt agtaaagact gcgtctgtca
      481 cacggctaga gacaaagatg gtaatcatag aataaagagc gtatttccaa ccaaaggtca
      541 aacctgctat cagcatgata gttccattta ccaagaaaga aatactaccg acattcttac
      601 ccgttttctt acgaatagtc aggctaacga tatccgtccc accactggag atattgtttc
      661 gaagagcaaa accaatcccc aaacccataa caacaccccc aaaaagggaa ttgataatgg
      721 gatcctccgt caaggttgcc acagggacaa actggataaa gaaggaactc atagataccg
      781 tgataaaggt aaagacggtg aacttatggc caatctgata ccaagctaag accatcaaag
      841 ggaagttaat ggcgtagaag cttagcgaaa tcggaatatg aaaaccaaac cagtgattac
      901 tcaaggcaga gataatctgt gccagacctg ttgcaccact cgaatacaca tgccctggtt
      961 ggaaaaagaa attaactgct actgctgata aaaaaccata gaccagagag gccgaaatct
     1021 tctcatcata cttttctcga gagatacttt gtaagacacg taaaattttt atctgataag
     1081 caaagcggcg cagataatag cgccaccgct taattcgttt tgtttgtttc atcttcttct
     1141 acttgtaagc tgagttcctc tagttgtttg agagcgactg ttgatggagc ttgtgtcatt
     1201 gggtcagttg ccttgttgtt cttaggaaag gcaatgactt cacggatatt ttcttctcca
     1261 gcaagcaaca tgacaaaacg gtcaagcccg atagccaaac caccgtgtgg tgggaaacca
     1321 tagtccatgg cttcaagaag gaaaccaaac tggtcattgg cttcttcagc tgagaaacca
     1381 agagccttga acatgcgttc ttgaaggtct ttttggttga tacgaaggct accaccacca
     1441 agctcataac cgttcaagac gatatcgtaa gcaatggcac gaaccttagc caaatcacct
     1501 tctaattcgt gagcagtctc ttcctgtgga agggtgaaag gatggtgggc gctcatgtag
     1561 cggccttctt cttcagacca ttcaaacatc ggccagtcaa ccacccaaag gaagttgaac
     1621 ttatcattat caatcaagcc aagctcttta gcaatacgtc cacgaagggc acccagtgtt
     1681 gcattagcca cttcaagcgt atccgccaca aagagaacca agtccttatc ttcaagagca
     1741 agcgctgttg tcaattcttc ttggatacca gtcaagaact tggcaactgg tccgtttaat
     1801 tctccatcaa ccaccttaac ccaagcaaga cctttggcac catactgttt ggctacttcc
     1861 gtcatcttgt cgatgtcttt acgtgaatag ttgtccgcag ctcctttgac cacaatcgct
     1921 tttacagcag gtgcttctga aaagacttta aagtctacac ctttgaccac ttctgtcaag
     1981 tcctgaagca acatgtcaaa acgagtatct ggcttgtcag aaccgtaaag agccatagca
     2041 tcatcgtatt tcatacgagg gaacggtagc gttacttcga tgccttttgt ttccttcatc
     2101 acgcgcgcga tcaagccttc tgtaatatct tggatttctt gctcagtaag gaaggacgtt
     2161 tccaagtcga cctgagtaaa ttcaggctgg cggtctccac gcaagtcctc gtcacggaaa
     2221 catttaacga tttggtagta acggtcaaaa ccagcattca tcaagagctg tttcgtgatt
     2281 tgtggacttt gaggaagagc gtaaaaatgc cccttattaa cacgagacgg tactaaataa
     2341 tcacgcgccc cttcaggcgt tgacttagaa aggaatggtg tctccacgtc gataaactcc
     2401 aactcatcca aatagttgcg gatagagtgg gtcaccttgg cacgaagttt aagattttcc
     2461 aacatttctg gacgacgaag gtcaaggtaa cggtaacgca aacgtgtatc gtcatttgcc
     2521 tcaatgccat ccttaatctc aaatggtgtt gtcttagctg tgttaagcac aataagagct
     2581 gtcacgttta actcaaccgc accagttggc aacttatcat tggcttgctc acgcgcagcg
     2641 acctgaccag tcacctcaat aacaaattcg ctacgaaggc tttcagctgt tgccataacc
     2701 tctgcagata ctttttcagg gttgataacc aactgcatga ttccttcacg gtcacgaaga
     2761 tcgataaaga tcaaaccacc aaggtcacga cgacggccaa cccatccttt caaggttatt
     2821 tcttgtccga tgtgttcctc acgaacacga ccagcataca tactacgttt cattatttct
     2881 ctcctctttt attctgttac tattttacca taaaagcgca ggctcttcat gaaaatcatc
     2941 agaaaagttt gccagtcttt aaaagtcagg tgaaagccct aaaaattagc gctaatactc
     3001 ttcgaaaatc tcttcaaacc acgtcagcgt cgccttaccg tagtacggtt
//
LOCUS       DAVLMQ010000111         2990 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000111 DAVLMQ010000000
VERSION     DAVLMQ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.112"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..370)
                     /locus_tag="VXF95_002148"
                     /pseudo
     CDS             complement(1..370)
                     /locus_tag="VXF95_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            409..1326
                     /locus_tag="VXF95_002149"
                     /pseudo
     CDS             409..1326
                     /locus_tag="VXF95_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            complement(1366..2310)
                     /gene="manA"
                     /locus_tag="VXF95_002150"
     CDS             complement(1366..2310)
                     /gene="manA"
                     /locus_tag="VXF95_002150"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HEV1082619.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEDELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDDLLTKVPVKAG
                     DFFYVPSGTMHAIGTGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTVKADNLRSTLLVSNDFFAVYKWEITGKVDFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVESWTLEGQDLELIVSHP"
     gene            complement(2442..2723)
                     /locus_tag="VXF95_002151"
     CDS             complement(2442..2723)
                     /locus_tag="VXF95_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HEV1082620.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYKDGVDLLGYTTWG
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGALKRSKKKSFYWYMSFIAMV"
     gene            2788..2910
                     /locus_tag="VXF95_002152"
                     /pseudo
     CDS             2788..2910
                     /locus_tag="VXF95_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          811 a          689 c          546 g          944 t
ORIGIN      
        1 aggtcgattg atttttactt ccgtcgcatc aatcattacc gtgtcctcag aactgagagg
       61 agttcttgaa atcgtaacac cacctttgaa caagagttac ttcaacccat tggctccgac
      121 ggagtaagtt gctttcgtgg ataccaaaat cagccgcaat ttcttcataa gttcgatatt
      181 ctcgcacata ttgaagagtg gccataagaa ggtcttctag gcttaattta ggttttcgtc
      241 caccttttgc gtgtttaagt tgataagctg tttttaatac agctaacatc tctttaaaag
      301 tcgtgcgctg aacaccaaca agacgcttaa atcgtgcatc agttagttgt ttacttgctt
      361 catcattcat agaactacta tgccatattt tgtttcgcag gaagtctgat catttcaaat
      421 ccagccattg ctctaggagc tcaagcgacc tttatcctat tgaatatctt cattgtatca
      481 cgtggggttc aaaaagggat tgaaagagct tcgaaagtca tgatgcccct gctctttatc
      541 atctttgtcg tcatcatcga acgctctctc agtttgccaa atgccatgga aggggttctt
      601 tacttcctca aaccagattt ttcaaaactg actagcgctg gtctcctcta tgctctgaga
      661 caatctttct ttgccctctc actaggggtt acagccatgt tgacctatgc ttcttacttg
      721 gacaagaaaa ccaatctggt ccagtcaaga atctccatcg tagccatgaa tatctcggta
      781 tccatcatgg caggtctagc cattttccaa gctcggtccc ccttcaatat ccagtctgaa
      841 gggggaccga gcttggtctt tatcgtcttg cctcaactct ttgacaagat gccttttgga
      901 accattttct atgtcctctt cctctttgcg actgtcactt cttctgtcgt tatgctggaa
      961 atcaatgtag acaatatcac caatcaggac aacagcaagc gtgctaaatg gagtgttatt
     1021 ttaggaattt tgacctttgt ctttggcatt ccttcagccc tatcttacgg tgtcatggcg
     1081 gatgttcaca tttttggtaa agccttcttt gacgctatgg acttcttggt ttccaatctc
     1141 ctcatgccat ttggagctct cttcctttca ctttttacag gctatatctt taaaaaggct
     1201 cttgcaatgg aggaactcca tctcgatgaa agagcatgga aacaaggact gttccaagtc
     1261 tggctcttcc ttcttcgttt cgtcattcca atcatcatcg tggtcttcat cgcccaattt
     1321 atgtaatcaa aaggacttga gtaatgaact caggtccttt cttttttatg gatgactaac
     1381 aattaattct aaatcttgcc cttctagagt ccaagattca acatcacttg gtaggataaa
     1441 gtgtctccct ttttggattg gatagttttt cccgtcaaca gttagttgac cttgaccagc
     1501 caagacactc aacaagctgt agtcagctgt cttctcaaaa tcaacttttc cagtgatttc
     1561 ccacttgtaa actgcgaaga aatcattaga aacaagtaaa gtggaacgca aattatctgc
     1621 tttaacagtt acaggacggc tatttgctgg ctcgccaatg ttcaaaacat cgatggattt
     1681 ttcaaggtga agttcacgca agttgccctt atcgtccttt cggtcaaagt catagacgcg
     1741 gtaagttgta tcactagact gttgggtttc aagaatcaag atgccagtac cgatagcatg
     1801 catggtgcca cttggtacat agaagaaatc tccagcctta acagggactt tggtcaacaa
     1861 gtcatcccag ttcttgtcct cgatttgctg gcggagttct tcttttgact tggcattgtg
     1921 accgtagata atctctgaac cttcatctgc tgcaatgatg taccaacatt ctgtttttcc
     1981 aagttcgtct tcatgctcga gtccataagc atcgtctggg tgaacttgga cactgagcca
     2041 gtcgttggca tcgaggatct tggtcaaaag tggaaataca ggttctggac gattgccaaa
     2101 taattcacgg tgttccgcat acaaagtagc aagatctgtt ccctcgtaac gaccattggc
     2161 aactttagaa acaccattta gatgagctga gatagcccag tactctccga ctttttcact
     2221 tgggatgtcg tagccaaact catcacgtag cttggtacca ccccagattt tttcttgcat
     2281 aactgattgt aaaaataatg gttctgacat cttaatctcc tgtctgattt ttctcccctc
     2341 attatagcaa aaaaagagtt ccatttgaac tcttttttac atcttataaa gcagggagaa
     2401 gattttataa aaatagtaaa caaatgtgct ctactcgatg cttacaccat tgctataaat
     2461 gacatgtacc aatagaagga cttcttcttg ctacgtttga gagctccgtt tcctacatta
     2521 tctcgatcta catagataaa gccatagcgc ttattcattt cccctgtgcc agctgaaacc
     2581 ggatcgatac agccccatgt cgtataacca agcaagtcaa ccccgtcttt gtaaatggca
     2641 tctcgcatgg ccttgatgtg ggcctctaag taagtaatcc gatagtcatc tgctacataa
     2701 ccattctcat ccggtgtatc catagcaccg agtccatttt ctacgataat actatactaa
     2761 aatcaaaaag cattatataa tagtgatatg aaatcaacta aagaagaaat ccaaaccatc
     2821 aaaacacttt ttaaagactc tcgtacagct aaatatcata aatgccttca aatcattcta
     2881 tttcgtctga tgggcaaatc ttataaagat tccgactaat attggtttta cctttattcc
     2941 tccatacaca ccagagatga acccatcgaa caagtgtgga aagagattca
//
LOCUS       DAVLMQ010000112         2918 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000112 DAVLMQ010000000
VERSION     DAVLMQ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.113"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(98..2356)
                     /locus_tag="VXF95_002153"
     CDS             complement(98..2356)
                     /locus_tag="VXF95_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HEV1082621.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VXF95_002154"
     CDS             complement(2585..2815)
                     /locus_tag="VXF95_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HEV1082622.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
BASE COUNT          785 a          603 c          607 g          923 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttatca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggggcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttggtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatt
//
LOCUS       DAVLMQ010000113         2914 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000113 DAVLMQ010000000
VERSION     DAVLMQ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2914
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.114"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..367
                     /locus_tag="VXF95_002155"
     CDS             <1..367
                     /locus_tag="VXF95_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013851451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082623.1"
                     /translation="LVNMITELSEDEIDRIEAQEEKKYVVTFPKWILDKAEKDVRARN
                     ESNNSSVVYYIDSENRLASIDIDEVEPLELISLLENPDVKKMLKEEILKKMLDGYYSK
                     LPRHIIKDIINSYQEKNIQ"
     gene            complement(922..1323)
                     /locus_tag="VXF95_002156"
     CDS             complement(922..1323)
                     /locus_tag="VXF95_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HEV1082624.1"
                     /translation="MLFFSISNDLLQLLTSWKEQQRYELAKFGILSNPEQFVFTYIDT
                     KGNINKPLHADYLNNKMKSIRKRHKELTHATPHKLRHTGATLAKKAGMSLEAISKALT
                     HSDTGTTQIYVNTSNVVPMTVGEFALKSLKQ"
     gene            complement(1699..2907)
                     /locus_tag="VXF95_002157"
     CDS             complement(1699..2907)
                     /locus_tag="VXF95_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1082625.1"
                     /translation="MNYIKRPHYLDFLRRHRDRQIIKVVSGVRRAGKSVLFQLYKEEL
                     IATGVDEDQIISINFEDLSYYDLRHFQTLFAYIKEQLIGEKTYYIFLDEIQHVEKFEL
                     VADSLFILPNVDLYLTGSNAYFMSSQLATNLTGRYVEIEVLPLSFEEYLSGQSLTENL
                     NTTEIFNNYLFSAFPYLLQTSSYAEKIDYLRGIYNSILLNDIVTRLGNPNPTIIERIV
                     RTLLSSTGSLISTNKIRNTLVSQNVSISHNTLENYLTTLTDSLLFYSVPRFDVKGRAL
                     LQRLEKYYPVDLGLRHLLLPDHKEDIGHILENMVYLELRRRYSQVYVGNLDKYEVDFV
                     VVTDLGHYAYYQVSETTLAPETLERELRPLDAIKDQFPKYLLTMDTIQPTANYNGIEK
                     KNIIDWLLEK"
BASE COUNT          957 a          435 c          513 g         1009 t
ORIGIN      
        1 actcgtaaac atgattacag agttatcaga agatgaaatt gataggatag aggcccagga
       61 agaaaagaag tatgttgtta cgtttccaaa atggatttta gataaagcag aaaaagatgt
      121 gcgagcaaga aatgagtcaa ataactcgag tgttgtatat tatattgatt cagaaaatag
      181 gttagctagc attgatattg atgaagttga accgcttgaa ctcatatccc tgctagagaa
      241 tcctgatgta aaaaaaatgt taaaagaaga aattttgaag aaaatgttag atggttatta
      301 cagtaaatta ccaagacata ttattaaaga cataataaat agttatcaag aaaaaaatat
      361 tcaatgaatt taataataaa atttcatcat ttagggcaaa ttactgataa agctgactcg
      421 ttttggttgg ttttgtagaa aaatttgccc tatttagatg aaaatggttg aaattagttg
      481 agaactagta aatatttggt agttaaaaat ggtttgatta aaggtaattg aaagaactta
      541 gttattaggt tagccaaacc aggtcttaag aaagctcgta aagcatcaca atttagtaag
      601 cgttaattcg aaagaattac tatacttata cagagcacct ttcggggtgt tcttttttta
      661 tactttctta ctaaattggt gtaattgaca cagttgttgc gactttagtc gcttacaaat
      721 gtggctgcaa cctgacaagg tcagttgcct caaaacgtta atcaatacga ttatatcaac
      781 gtttcaaagc actcaaaagt tcaccttatt tttatagtaa aatgaaataa gaataggaca
      841 aatcgatcag gacagtcaaa tcgaattcta acaatgtttt agaagtagag gtgtactatt
      901 ctagtttcaa tctactatac cttattgttt tagagacttt aaagcaaatt cacctactgt
      961 cataggaact acattagaag tatttacata aatctgtgtt gttcctgtgt cactgtgtgt
     1021 tagagcctta gaaatggctt ctaagctcat tcctgctttt ttagcaagtg tcgctcctgt
     1081 atggcgtaat ttgtgaggtg tagcgtgtgt cagttcttta tgtcgctttc taatgctttt
     1141 cattttattg ttcagatagt cggcatgtaa aggcttgttg atgtttcctt ttgtgtcgat
     1201 atatgtaaaa acaaattgtt ctggattact gaggatgcca aactttgcta gttcatatct
     1261 ttgttgttct ttccaagagg taagaagttg aagtaaatca ttagaaatag agaaaaatag
     1321 gatagcaaaa gctctatttc aggagaaaat gaagcaaata tttccataat aaaacgcata
     1381 ttatcaaggt tgttcaatac ctgatactat gcgcttttct gattttaaag actgattgct
     1441 cagtctcttt ttcattataa ttcagttaca atttaatctt atttgagaaa gtgggtgatg
     1501 ctattctcta ataagactat gatattaatt tttgatagta cttccagaaa ttatagatcc
     1561 cctttcatcc ccaatttcta ttttcaagtg tccgtattat atagcgtatt cgaaattcac
     1621 tatatcttgt taggatttgg gtagaatcat tgataacaga ctgttgcaaa tctaattagc
     1681 tgtatgattt atatttatct atttttctag taaccaatct ataatgtttt tcttctcgat
     1741 tccattgtaa ttggctgttg gctgaatcgt atccattgtt aatagatact ttgggaattg
     1801 atctttaatg gcgtctagtg gtctaagttc tctttctagt gtttctggag caagtgttgt
     1861 ttcactgact tgataataag cgtagtgacc aagatcagtt acaacaacaa aatcaacctc
     1921 atatttatct aaattaccaa catatacttg tgaatatcta cgtctcaatt ccaaatagac
     1981 catattttcc aagatatggc caatatcttc tttgtggtct ggcaataaga ggtgtcgtaa
     2041 acctaaatca acgggataat atttttctaa gcgttgcaat aatgctctac cttttacatc
     2101 aaaacgtgga acggaataaa aaagcaaact atctgtcaaa gtcgtcaaat aattttccaa
     2161 agtattatgg gagattgaaa cgttttggct gaccagggta ttgcgaatct tatttgttga
     2221 tattaagcta cctgtactac tgagaagggt tcggacaatg cgctcaataa tagtaggatt
     2281 tggatttccc aatctagtga caatatcatt taacagtatg gagttatata ttcctcttag
     2341 ataatcaatt ttttcagcgt aagatgatgt ttgcaataag taagggaaag cactaaagag
     2401 ataattgtta aaaatttctg ttgtattcag attttctgtg agagattgac ctgatagata
     2461 ttcttcaaat gacaatggaa gaacttctat ctcaacatac cgaccggtca agtttgtagc
     2521 taattggcta ctcataaagt aggcgtttga tccagtcaaa tagaggtcaa catttggtag
     2581 tataaataga ctatctgcta ccagttcaaa tttttcaaca tgttgaattt catctaaaaa
     2641 gatatagtat gttttctctc caattaactg ctcttttata taagcaaata atgtttgaaa
     2701 atgtcggaga tcatagtaac tcagatcctc aaaattgatg gatatgattt gatcctcgtc
     2761 taccccagtt gctattaact cctctttata gagttgaaag agaacagatt taccagctcg
     2821 cctaactcca ctcacaactt tgatgatttg tcggtcacga tgtcttctta aaaaatctaa
     2881 ataatgtggt cttttgatat agttcataat agtt
//
LOCUS       DAVLMQ010000114         2773 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000114 DAVLMQ010000000
VERSION     DAVLMQ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2773)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2773)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2773
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.115"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>2773
                     /locus_tag="VXF95_002158"
     CDS             <1..>2773
                     /locus_tag="VXF95_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV1082626.1"
                     /translation="LSRTKNELSGVKSAQATYEETTTRRLSELTNLANGKASKSELTQ
                     TAEELASRIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDY
                     VRISFDVTFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSED
                     YQTNNVFIRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQ
                     RADSLDAGVSRLTEGLRTKADISSLNVTAENIRQSVKRLETDTQNKLNQKLSQAEFEV
                     RAGSIRQEILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDISKTGI
                     WTTSTYTAAIDSESKYLGYNALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQ
                     DVTISFYAKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNE
                     WLFNFNQEGTVWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRANSLEAGVNR
                     LTEGLRTKVDISALNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILN
                     ATKDKASKSELTQTAEELASKIASVHLGRRNLLKGTKELARYKPVSEYNGFKVIRTVA
                     GATRYQDSYVERTVIPTAGTEYIAIFYARASENDYPVRCHFYNPNTVVSSENSSGYKS
                     RSSDGLSIIRLSTDWQLCWVKWTQTATDQAKTVIIGRHGPQVGGKEGVWVEICAPAIF
                     EGNLAGDWSPAYEDQDERVSAVESNFKQRADSLEAGVSRLTEGLRTKADISSLNVTAE
                     NIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQEILNATKDKADKTLVVSEAGKLR
                     EEFSKMKVGGRNLWIKSKTVGAVIEKLPENHVTGQKECYRLENNSTLTFNIEPDFSSR
                     LYQKVTFSAW"
BASE COUNT          862 a          558 c          675 g          678 t
ORIGIN      
        1 acttagtcgg actaagaatg aactgtctgg cgtgaagtca gcgcaagcga cgtatgagga
       61 gacgacgact cgtagactgt cagaactgac caacttggcc aatggtaaag ccagcaagtc
      121 agaactcacg caaacagctg aggagctggc tagtcggatt gcgagtgtgc aggcaggtag
      181 ttcacggaat tacttcagga attcacgttc aagaacgttc acaacaggag gtcaagcggt
      241 atacgactat cgaacattca tagttcctga tttctggaag aacagtgaca ggttcaagcg
      301 tgattatgtt cgcatatctt ttgatgtgac tttccctgtc gccctagtaa atgacatgcc
      361 tgctatggtg cattttagtg ctcatccatg gtatgcctac agaaacttaa tttttaaagg
      421 tggaactgtc gaacgccaac attttgagtt tacgattgac ttgtctagtt cttctgagga
      481 ctatcagact aataatgtgt tcattcgttt tggtactaat tatggatttc ctgctggtct
      541 gcaggtcgtc attgagaacg ctatgttatc ggttggtaat tattttccag cctatcaacc
      601 agcgtatgaa gaccaagaag accgtgtctc agtagtcgaa tccaacttta agcagcgtgc
      661 tgattcactc gacgctggtg taagccgtct gactgaaggc cttagaacta aagccgatat
      721 cagctcactc aatgtgactg ctgaaaatat ccggcaatct gtgaagaggc ttgagacaga
      781 cacgcagaac aagctaaatc agaagttgag tcaggctgaa tttgaggtgc gagctggctc
      841 tatccgtcag gaaatcctga atgcaaccaa ggataaagcc agcaagtcag aactcacgca
      901 gacagctgag gagctagcta gtcggattgc gagtgtgcag gcatccggtc gaaatctatt
      961 cttgaactca ctattcaagc aggatatttc aaaaacagga atttggacaa cgagtacata
     1021 tacggctgct atcgatagcg aaagtaagta tcttggatat aacgctctta aaattatagg
     1081 tctgaatcca tctggccgtg atggagggaa tcccaaggtt acttatccag ctctgggtca
     1141 attcgggaaa gtaattcccg gaagtacgac taatcaagat gtaaccatta gtttttatgc
     1201 taaggcaaat aaaaatggaa taatgctaag atctcgatta gggaatatcg gatataaaac
     1261 tggaaatgtg acattgtcga cagaaattaa acgatatgtt gtccatattc caaaaggttg
     1321 gacaaacgaa tccaagcaga ccacaaatga atggttgttc aatttcaacc aggaaggaac
     1381 cgtttggatt tggatgccga agtttgaaat aagcgatgta gatacttctt attcagaagc
     1441 tcctgaagat atagaaggtc agatttcaac agttgaatcg acctttaaac aacgagccaa
     1501 ctcgctcgaa gctggtgtga atcgtctgac tgaaggcctt agaaccaaag tggatatcag
     1561 cgcactcaac gtgactgctg aaaatatccg gcaatctgtg aagagtcttg agacagacac
     1621 gcagaacaag ctaaatcaga agttgagtca ggctgaattt gaggtgcgag ccggctctat
     1681 ccgtcaggaa atcctgaacg caaccaagga taaagccagc aagtcagaac ttacgcagac
     1741 agctgaggag ctagctagta agatagcgag tgtgcactta gggcgcagaa atctgctgaa
     1801 aggcacaaaa gagcttgcga gatacaagcc ggttagtgaa tataatggtt ttaaagttat
     1861 cagaacagtc gcaggagcaa ctagatatca ggatagctat gtggaaagaa ccgttatacc
     1921 aacggctggg acagagtata tagctatctt ttatgcacga gccagtgaaa atgactatcc
     1981 tgtgcgctgt catttttaca atcctaacac ggttgtatca tcagaaaaca gcagcggata
     2041 taagtcaagg tcgtcagatg gcttgtctat tatccgtctc tcgacagact ggcagttgtg
     2101 ctgggttaaa tggacccaaa ccgcaacaga tcaagccaag acggtcatca ttggccgcca
     2161 tggccctcaa gtaggcggta aagagggggt atgggttgaa atctgcgccc ctgccatttt
     2221 tgagggaaat cttgcaggtg actggtcacc agcatacgaa gaccaagacg aacgtgtctc
     2281 agcggtcgaa tccaacttta aacagcgtgc tgattcactc gaagctggtg taagccgtct
     2341 gactgaaggc cttagaacca aagccgatat cagctcactc aacgtaactg ctgagaatat
     2401 ccggcaatct gtgaagagtc ttgagacaga cacgcagaac aagctaaatc agaagttgag
     2461 tcaggctgaa tttgaggtgc gagctggctc tatccgtcag gaaatcctga acgcaaccaa
     2521 ggataaagca gataagactt tagttgtatc tgaagctggg aaattgcgtg aagaattttc
     2581 aaaaatgaag gtgggaggac ggaatctatg gataaaatcc aagacggttg gagctgtaat
     2641 tgaaaaatta cctgaaaacc acgtcacagg tcaaaaagaa tgctataggc tagagaacaa
     2701 ctctacttta acgttcaaca ttgaaccaga tttcagctca aggttgtatc aaaaagttac
     2761 ttttagcgct tgg
//
LOCUS       DAVLMQ010000115         2727 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000115 DAVLMQ010000000
VERSION     DAVLMQ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2727)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.116"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..357)
                     /locus_tag="VXF95_002159"
                     /pseudo
     CDS             complement(1..357)
                     /locus_tag="VXF95_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810555.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(415..1128)
                     /locus_tag="VXF95_002160"
     CDS             complement(415..1128)
                     /locus_tag="VXF95_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HEV1082627.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFAHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLAPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAEFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            complement(1587..1967)
                     /locus_tag="VXF95_002161"
     CDS             complement(1587..1967)
                     /locus_tag="VXF95_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HEV1082628.1"
                     /translation="MESIGIGLVIVSHSKHIAEGVVELISKVAKDVPITYVGGTEGGG
                     IGTSFDQVDRVVSENPADTLLVFFDLGSAKMNLKMVTDFSDKSIIINRVPIVEGAYNA
                     AALLQAGAELSVIQIQLAELEINK"
     gene            complement(2389..>2727)
                     /locus_tag="VXF95_002162"
     CDS             complement(2389..>2727)
                     /locus_tag="VXF95_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="HEV1082629.1"
                     /translation="KPSEEKPQTEKPEEETPREEKPQSEKPESPKPTEEPEESPEESE
                     EPQVETEKVEEKLREAEDLLGKIQDPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAE
                     KLLALLKESK"
BASE COUNT          837 a          531 c          434 g          925 t
ORIGIN      
        1 ttaacttttt gttcgtaggc atattttgct acatgatcta ggtatatatc aaaaaaagtc
       61 atgaggaaaa tctcccatac agccattacg attcatattg aggctatatt ttcgattagt
      121 aagataattc ggaaatatat ttcctattac tctaagatta tctacttgtg aatcccttct
      181 cccaatataa tccccttctt tgactaatga tggagatttc caagtaaaaa ttaaatcgcc
      241 agagaaattt ttcttatcaa aaaacttaaa aagagattga taaatactat ttgctaattg
      301 acaagtgtca gatgtaaatt cataagtaac agcttcatta aaatcaactt cagacatttc
      361 aatgtactct tcaatagtaa tattagcttt tttgtagtca ttagctcgtc tcctttaaaa
      421 tgtgatcttt tcaagaatat ttttatctaa acaatccagc aagtcttggt aagaatagac
      481 ttcgtaagtc ggctgggctt gtgtgtgatt ttcgaggtga tgaggattat accagatagt
      541 gtcaatcccc gcattattgc caccttgaat gtcggcagtt agagaatctc caatcatcag
      601 cgtcttttct ttactaaatt cagcaatttg ctggccaatc ttttcataaa agagagcatc
      661 cggcttttga gtttgcaact gttctgagat aaagacttga ttgaaataag gtgctagacc
      721 agattgagcc aaacgtcctg tctgaatggc agtaatgcca tttgtcgcag catacaagtt
      781 ataatcacgc tcaatgaggc tgtccaagag atcatgagcg cccgatagtg tttgtccctg
      841 ctgggcgagg taaaattggt aacgctgggc aagaaaacta ccgtcttttt cctgtccaaa
      901 atgagcaaat aaacgagaaa agcgcgtgtt aaccagctct tgtttactga ttttcttcag
      961 ctccaagtct ttccagagag ccttgttcat aggaacgtaa taatctttat aagcctgaat
     1021 atccgcaact ccttcttctt ttagaagttg ggtcaaagcc acatcctcag cagcatcaaa
     1081 atcaagaaga gtgtggtcga ggtcgaagag tagaaatttg tagaacaatt tgaggttttc
     1141 ctttctgaaa attcattaag aacattatat cataaagcac ctcatacaat taactaattt
     1201 aatcacttaa aaaaaattcg aacactttct atacaactga cagctcaaat ctttcagaat
     1261 agaacaatac taactatcga gcaccccgtc ttcataaata tatgtgtaat tctagaccta
     1321 gaattcttat aaactaaatg ctttcatact cttccaagta attgattgcc ttaaatttta
     1381 atttttgaag gattctaaag ctagaatagt cccatcacaa tcagttttga ttgattcaca
     1441 atttagaaac actatagttt cactcctgtt aaaataaaaa ggaactgcat aaagcaatcc
     1501 ctttctgatt ttgaaatcat ttacttaaca ttttatagtt gagataatca atagcttacc
     1561 tataaaaaga gttatagtaa aattccttat ttattgattt caagctccgc taactgtatt
     1621 tgaataactg acagttctgc accagcctga agaagagcag ctgcattata ggcaccttct
     1681 acaattggaa ccctgttgat gatgatactt ttatcactga aatcagtcac catttttaag
     1741 ttcattttag cagaacctag gtcaaaaaat acaagtaaag tatctgctgg attttcggaa
     1801 acaaccctat ctacttgatc aaaactcgtt ccaattcctc cgccctcggt tcctcctaca
     1861 taagtaatcg gaacatcttt agctacttta ctaatcagtt caacaacacc ttctgcaatg
     1921 tgtttggaat gtgaaacgat aacaagacca ataccaatac tttccatcaa accactccag
     1981 tttctaaaat agcagtaaag agtaatcctg atgagaatga tccaggatca atatgtccaa
     2041 gaaaccacat gctcctaaga caagagctaa cagactggcc gtcaataata gtattgttct
     2101 ttttttcatc attactcctt aactagtgtt taactgatta attagccagt aaatagttta
     2161 tctttattta cactatctgt taagatatag taaaatgaaa taagaacagg acagtcaaat
     2221 cgatttctaa caatgtttta gaagtagagg tatactattc tagtttcaat ctactatatt
     2281 ttgcacattt tcatgaaaaa aatgagaact agaactcaca ttctgctctc atttttcgtt
     2341 ttcccgttct cctatcctgt ttttaggagt tagaaaatgc tgctaccttt acttactctc
     2401 ctttaataaa gccaatagtt tttcagcttc tgccataata gtattgttgt cctgggtgcc
     2461 aaatagtaaa ttatttttta atcctgtgag agtctctttg gcattggact tgataattgg
     2521 atcctggatt tttccaagta aatcttcagc ctctctcagt ttttcttcaa ccttttcagt
     2581 ctcgacctga ggttcttctg attcctctgg tgattcttct ggttcctctg ttggttttgg
     2641 agactctggt ttctcgcttt gcggtttctc ttctcgaggg gtttcttcct caggtttttc
     2701 tgtctgaggt ttctcctcgc ttggttt
//
LOCUS       DAVLMQ010000116         2708 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000116 DAVLMQ010000000
VERSION     DAVLMQ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2708
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.117"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(162..1472)
                     /locus_tag="VXF95_002163"
     CDS             complement(162..1472)
                     /locus_tag="VXF95_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HEV1082630.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            1709..2581
                     /locus_tag="VXF95_002164"
     CDS             1709..2581
                     /locus_tag="VXF95_002164"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HEV1082631.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAIMLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT          829 a          461 c          637 g          781 t
ORIGIN      
        1 tttttaaagt tgaactaatc atttttacag gatgagattt acagcagaga gtttgaaggc
       61 tttatcaaag gtttttcttg gcataatgac ttttcctcgt ttccacttaa ttttgtgtct
      121 actttattat accaagtcca cccttaagtt agataataaa tctaacttaa ggaagctaga
      181 aggatgagaa tccaggtggt caagagtccc aaacttaagc tgatggggac acccagaata
      241 atttgctttt tgaaggcaag gccacgttcc tctatattgg gaagtgagag ttgaatgaga
      301 gaaccagctg atgaaaaggg tgagatatta gtagatagag cgccaataac ggtggctgtt
      361 gtgagtaagt gaatatcaat ctgaggattt tgagcactga tgatagcaat gatgggaaag
      421 agggctggag ctacaacgga tagggtggaa ctaaagagtg acatcactcc ggctatcaca
      481 caaaagaaca gaggtaacca gaaatgagga atggttgttg tcatgaggtg ccctatcagt
      541 gtgactaaac ctgacttgac cgctagagac attagtaagc tcatgccgca gagcatgata
      601 attgtagccc agggaacctt agctaaaatg gcttcttgct tccctaattt gagccttaag
      661 gcgaggcaga ccatgagtat tgagacaaag ccaatatcaa atgttttttg ataagtagct
      721 atccaggcga tgtttgggaa aatgagatgc aacaagggaa aaagccaaac caaaaccatg
      781 ctgctgatca tgagcaaggt ggtttgtctt tgaaccttgc tgaggagtgg tggttggtca
      841 atagtcaagg atgagtttgt tcttccctta ctatagtgac tgtaacagga taataaaagc
      901 aagacgatga gtgggtagat aatgctgacg ataaagatat gattgccaag tgaaaaagct
      961 tgctcctccc atcccatttg cttaaacagg ccttgaaaga caatgcctga gctactggtt
     1021 atcaaattag cccctcctga agctccccaa ttgacggctt gagctccaat caaagggtgt
     1081 ttgtccgctt tttgacagag ggtaatcgct agaggacagc aaacggccat agtagtgaaa
     1141 aatccagcac ctaaagcaga caaaagggtt gccatcaggt ataaaatcat gtagagggcg
     1201 ttagggtggg tgcgtgtgcg gtagagaatg tgttgagcca aaacatcaag agtaccgtta
     1261 gttgttgcaa cgttataaaa gagagagacg ctaaaaatgg taaaaaagag tgaggttggc
     1321 caaaaatgaa gaagttcttt ggggcttaat cccatgagag tggttgcgat gaggtaagaa
     1381 aaagcaatag ccagcaggcc aatattgatt ttggtgcggt aaccaattcc aatggctaga
     1441 gcaatggcgc taatcattat taaatgaatc attgaattgt cctttcagtt agaatatgga
     1501 aataggttgg caattttggc gctcaaaaga ccacctgttt cctattggta cttgactatt
     1561 atacacaaaa aaaatacaat tgtcttgaca attgtattga cacttgttag aattaaaaat
     1621 gaggtattca ggcttgtgat ttcctatgga agttaatagt aattgcctct agtgcttaca
     1681 agtgatatta aaaatagagg acttagtgat gtcaatcatt tcaactgatt taaccccttt
     1741 tcaaatagat gatacattga aagcagcctt gcgagaagat gttcattccg aagattacag
     1801 taccaatgcc atttttgatc atcatggcca agccaaggtg tcgctttttg ccaaggaagc
     1861 tggtgtttta gcgggactaa ccgtttttca aagggttttt accctatttg atgccgaggt
     1921 gaccttccag aatcctcatc aatttaagga tggggatcgt ttgactagtg gcgatttggt
     1981 tttagaaatc ataggctcgg tgagaagtct cttaacatgt gaacgcgttg ccttgaattt
     2041 tttacaacat ttatcaggga ttgcttcgat gacagctgct tatgtagaag ccttaggcga
     2101 tgattgcatt aaggtatttg atactcgaaa aactactcct aatttacgtc tttttgagaa
     2161 atatgccgtg agagttggcg gtggctataa tcatcgcttt aatttatcag atgctatcat
     2221 gctaaaagac aatcacattg cggcagtagg tagtgttcaa aaggcaattg ctcaagcgcg
     2281 tgcctatgcc ccttttgtga aaatggtcga ggtggaagtg gaaagccttg ctgctgccga
     2341 agaagctgcg gcggcgggtg ctgatattat catgttggat aatatgtcat tggaacagat
     2401 tgaacaggcc attaccctaa ttgcaggacg ttctcggatt gaatgttctg gaaatattga
     2461 tatgaccact attagccgtt ttcgtggttt agcgattgat tacgtctcca gtggtagttt
     2521 aacccatagt gctaagagtc ttgatttttc catgaagggt ttaacctacc ttgatgtcta
     2581 agttgtaaaa taaactaact ttttaaagga tgtctttcct ctagaacgag ttttatgtca
     2641 gatagtttaa acgcctcttc aaatatagta aaatgaacca aaaatagtac aaaatgaggt
     2701 ataatctt
//
LOCUS       DAVLMQ010000117         2661 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000117 DAVLMQ010000000
VERSION     DAVLMQ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2661
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.118"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            251..565
                     /locus_tag="VXF95_002165"
     CDS             251..565
                     /locus_tag="VXF95_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082632.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            575..781
                     /locus_tag="VXF95_002166"
     CDS             575..781
                     /locus_tag="VXF95_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082633.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            781..978
                     /locus_tag="VXF95_002167"
     CDS             781..978
                     /locus_tag="VXF95_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082634.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVIEWIEKKSKNLASEKGE"
     gene            1037..1717
                     /locus_tag="VXF95_002168"
     CDS             1037..1717
                     /locus_tag="VXF95_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HEV1082635.1"
                     /translation="MGMFVGMFKARVESHEIILDVKALMPWISAICLLIGFISMFLTF
                     NFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNITGVAIPLAIFISLSEV
                     IILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFATPKDVLNYINSYDEG
                     ERQANLEQSFRILFQLHQYVLPALYIFLIILSFLTGEIQLLAFLLVGAIHVYINVMQL
                     PMVKRYFK"
     gene            1729..2370
                     /locus_tag="VXF95_002169"
     CDS             1729..2370
                     /locus_tag="VXF95_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082636.1"
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLL
                     YVVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYVSRKGLVYSISLHALNNLVGFLMILML"
     gene            2388..2618
                     /locus_tag="VXF95_002170"
     CDS             2388..2618
                     /locus_tag="VXF95_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082637.1"
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
BASE COUNT          778 a          436 c          547 g          900 t
ORIGIN      
        1 actgttttga ggttgtagat agaactgacg aagtcagtaa ccatacctac ggcaaggtga
       61 agctgacgtg gtttgaagag attttcgaag agtattaatg atagataaag tggtcaggaa
      121 cttactcctg acctttttct tttgcaaaat gacaaaaatc ataaactttt tgacaaatat
      181 acttgtcaaa aagaaaaaga tatgttacaa tgaattcaag ttaagaaata ggaagcagaa
      241 aggagttata atgtgggtac taggatttat actatttatg attttctttt attctaataa
      301 ttctaaaaaa atcaagaaac tagagaataa aatcaaaaaa cttgagcgaa aagagaaagg
      361 aaacgcagaa atgtcgagat tattacaaga aatgattgga aaggaaccaa ttataacggg
      421 agtgtatatt gggccagata actgggaagt tgtggatgtt gatgaggaat gggtcaaact
      481 acgtagtgtt gataatacgg gaaaagaaaa attcaagttg caacgtattg aagatatcca
      541 aaccgttgaa tttgacggag agtaggtgtg taacgtgcaa ctaaaaaatc gtctaaaaga
      601 gcttcgagct cgcgatggtc tcaatcaaac cgacctagcc aaactggcag gggtttccag
      661 acagaccatt agcctactag aacgggatga gtacacccca tccattatca ttgccctgaa
      721 aatatctcaa attttcaacg aaacagtcga atcggtattt cgtttggagg aggacgagtg
      781 atgaacaagt ataaagtgat ttattatgta gtggtcatag ctttattagt cagcgtattt
      841 ctactgattg ggatggacct aagctggttt aatccctatc aaagcgacca atttgtttgg
      901 gtctactttg ctctcatccc agtaattgaa tggattgaaa agaaatccaa aaatctagca
      961 agtgaaaaag gagaatgaat atgaaaaaga aacgtagatt gttatttttg atgtctattg
     1021 tcttgggggg ggggtcttgg gcatgtttgt agggatgttt aaggcacgtg tcgaatccca
     1081 cgaaattatt ttagatgtaa aagccttgat gccatggata tcagctattt gtttactgat
     1141 aggtttcatt agtatgtttt tgactttcaa tttcttaaag aaaagcagaa aatttcattc
     1201 cttgtatcaa gaggaaatgg atgacgatct gaatgaaacc tattatgtgc aaatgtatcg
     1261 gaatcttgag tttggaacca ttgcttttaa tattacaggt gtagcgattc cattggctat
     1321 ttttatttca ttaagtgagg tgattatatt gcatacaaac cctcaaacat ttttcctttc
     1381 tttcttactc tttgtggtat tcttagtcgc tcaaaaatct ctttttaaaa ccattgcgat
     1441 tgttcgtcag tttgatttgg aatttttcgc tacaccaaag gatgtcttga actatataaa
     1501 ttcttatgat gaaggggagc gtcaggctaa tttggaacag agttttcgaa ttttattcca
     1561 attacaccaa tatgtcttac cagccttata tatttttctt attatccttt ctttcttgac
     1621 aggagagatt cagttactag ctttcttgct tgtaggagcc atccatgttt atatcaatgt
     1681 gatgcagtta cctatggtaa aacgttattt caaataaagg agttatctat gaaattactt
     1741 aaaaatcttg gctggtttct tctagccctt ctatcctttt tctttatcta tggctttatt
     1801 caggggctcg cgactgcgtc gcttgcttta ggcgcttcac cctatgctgt tactctactc
     1861 tatgtggtct tggctggagt atatgtgtac ggcatttaca aatggtatca gaaagctcct
     1921 gtttatattg agaagagcgg ctttaaccga tttatttggc ttcctgcctt ggtttggttc
     1981 ttatctctgg tcgttcaatt cttcttgcca gatgatcctt cagtaaatca acaaatagcg
     2041 acagacttga ccttgtctca accacttttc tcattctttg ctgtggttat ttttgctcct
     2101 ttgacggaag agattgtttt tagagggatg ttagcacgct atctctttcc taagcaggac
     2161 aatagtaaac gaaccctgat ttttcttctg gtatctagtc ttctatttgc cttgattcat
     2221 tttccaggtg atgtgcaaca attttttgtc tattttagcc ttggttttag tttgggtttg
     2281 gcttacgtta gcagaaaagg tctggtctac agtatttctc ttcacgcttt gaataattta
     2341 gtcggctttt tgatgattct catgctataa tagagtcagg aggtcacatg aaacgagtaa
     2401 ttttattagc agtgattcag gcagtcgttc tatttttcat cattggagcg ctagcttatg
     2461 ccttcaaagg cgatttcttc tataactatc tagcagttgt ctttgctcct attgcaggtg
     2521 tactgcgttt tgggacggct tacataacgg aaattgtctt gcctcgaaag gcagccgaaa
     2581 tcgctgaaaa gcgtaaagca ggcaaaaatt caaaataaaa gagtccggtg aagttcatcg
     2641 gatttttgta ttatactcaa t
//
LOCUS       DAVLMQ010000118         2646 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000118 DAVLMQ010000000
VERSION     DAVLMQ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.119"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..1218
                     /locus_tag="VXF95_002171"
                     /pseudo
     CDS             1..1218
                     /locus_tag="VXF95_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1434..1774
                     /gene="tnpB"
                     /locus_tag="VXF95_002172"
                     /pseudo
     CDS             1434..1774
                     /gene="tnpB"
                     /locus_tag="VXF95_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
     gene            complement(1807..2646)
                     /locus_tag="VXF95_002173"
                     /pseudo
     CDS             complement(1807..2646)
                     /locus_tag="VXF95_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          881 a          499 c          520 g          746 t
ORIGIN      
        1 atggcataga aatcgttaaa aaggggaaga atcgtcacta ttcttctaaa ttgaaacaag
       61 aaatgatgga taaagcctta ctggaaggtt gttcacaaag aagtgttagt cttgattatg
      121 ccctcccaaa ccaaggaatg ctttcatttt ggctggcaca atacaagaaa aacgggtata
      181 ctattgttga gaaaacaaga gggagaccag ctaaaatggg acgtaaacgg aagaagactt
      241 gggaagaaat gacagaacta gaacgactcc aggaggagaa tgaacgctta cggactgagg
      301 tggcctacct aaaaaagtta aaagagttag aggaaaggga cgaagcccta gagcgagaaa
      361 ggcagagaca gttagagaaa tggtttcagg aggatttcga ctagattttc ttcttgaaac
      421 agcacgttta gctcgctcga cttactatta tcagttgaaa caactggatg gggttgataa
      481 agataaagag attaaaacct aaattcaggc catttataat gaacataaag gcaactatgg
      541 ttatcgtcgg atttatttag aactaagaaa tcgtggttat ctggtaaatc ataaaagagt
      601 tcaacacttg atgaagtact caatttacaa gctaaaacgc gacagaaacg aaaatattct
      661 tctcataaag gagacgttgg caagaaagca gagaatctca ttcaaggcca atttgaaggc
      721 tctaaaacaa tggaacagtg ctacacagat gtgactgaat ttgccattcc agtaagtact
      781 caaaagcttt acttatcacc agttttagat ggctttaata gcgaaattat cgcctataat
      841 ctttcaactt cacccaactt agaacaagta caaacaatgt tggaacaggc attcacagag
      901 aagcactacg agaatacgat tctccatagt gaccaaggct ggcaatatca acacgattct
      961 tatcatcggt tcctagagag taagggaatt caagcatcta tgtcacgcaa gggaaacagc
     1021 aaagacaacg gtatgatgga atctttcttt ggcattttaa aatccgaaat gttttatggc
     1081 tatgagaaaa catttaaatc acttaaccaa ttggaacaag ccattataga ctatattgat
     1141 tactacaaca ataaacgaat taaggtaaaa ctaaaaggac ttagccctgt gcaatacaga
     1201 actaaatcct tcggataaat taattgtcta actttttggg gggcagtaca ctacacctac
     1261 tattatacgt ttttatcatt ttgaaatcta ctgctaatca atgaagaagc aaagatcaaa
     1321 ctaggcagct agttacaagt tacgtaagcg cgtcataaca aggtatctat cctaattccc
     1381 caacttccag tatactagat aaaaaataat tatcggagga aaggtattgt actatgataa
     1441 ttcaactaag tgatttaggt caagttcacc ttgtttgtag caagatagat atgaggcagg
     1501 gaatagactc attagcctat gtagttaaaa cccactttga attggatcct ttctccggtc
     1561 aagtctttct cttttgtggt ggacgtaaag accgctttaa agccctttac tgggatggtc
     1621 aaggattttg gctactatat aaacgctttg agaacggcag actgacttgg cccagtacag
     1681 aaaaggatgt caaagctctc acacctgaac aagtagactg gcttatgaag ggcttttcta
     1741 tcactccaaa aataaatcca tcagaaagtc gtgatttcta ttgaaatgag gactttcttt
     1801 ttatactcat ctgctttcaa aaagcattct agtccatctc cgattaacga tgggctttat
     1861 cacctccttc tccagtcctt gtatgatatc ttaaagttga ttcatgacat cttccaaagt
     1921 ttgaaaggct ttatttttaa atccacgttt acgaatctct ttccacactt gttcaatggg
     1981 gttcatctct ggtgtgtacg gaggaataaa tgcaaagcca atattagtcg gaatctttaa
     2041 ggtacttgat ttatgccata tagcattgtc cataacgagt aaaaggataa gcttgtgaaa
     2101 gctcttctaa aaaggcgttc atccactcag tattacatcc accagctatt aagaaaaatg
     2161 attcgcctgt ataggcataa caatagcgaa attctcgtat atagtgacta tggacatgtg
     2221 gacctactcc tattggagcc caacaagatc ccagtttact gattctaccg aaaccagcct
     2281 catcttggta catcaagcga accttacgaa aacgtctact ggttttaaat cgctttcttt
     2341 tcttcttgaa ttgagatttt atttttagac gcgacaatgg tttgagcgtc tgctttccta
     2401 ggatgttctg gacgtggcat aatatttcgc caaccatggc gcttcaacag ttgatagaag
     2461 gcatcacgtg tgtaggaacg acctaactcc tttttataag cctgaaataa ggcatcaatt
     2521 gtaacaaatt ctcctgcatc tgtagtcttc aaatgacggg caagaaaggc tttctcttgc
     2581 tcaatcgtca tatatgcatg gttacgacca ccacgtgttt cttgaaggag agagtcgagt
     2641 ccgaac
//
LOCUS       DAVLMQ010000119         2606 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000119 DAVLMQ010000000
VERSION     DAVLMQ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2606)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2606)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2606
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.120"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..553
                     /locus_tag="VXF95_002174"
     CDS             <1..553
                     /locus_tag="VXF95_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082638.1"
                     /translation="FWIVVHSGFIKYIKKNHRPVIITTWLVISLLSIIFFFKHIINNS
                     ESYTHRVLGIVNFFKYYESSKFHLFFGDAELAFGDMTKGYTHNIRSVLGWDGTVEMPL
                     LSVMIKNGYVGLIGYGVVLFKFISSVLSMEDRRVKNIGLSILIPLLLSAMVENYIVNI
                     SFVFMPVCFCILCSIKNIEFKNN"
     gene            563..1531
                     /locus_tag="VXF95_002175"
     CDS             563..1531
                     /locus_tag="VXF95_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HEV1082639.1"
                     /translation="MKKVSIILPVYNVEQYIKKCLESIQQQTYPNLEVIIVNDGATDK
                     SVEYCEQICKIDSRFSVTHKENGGLSDARNVGIDKAKGDYLIFVDSDDFVSQDMVSYL
                     VSSMENNEADIAICDPAHYYSDRQNNDLNIFYPASSVKVYEKTEALCEMFYQKSFLVS
                     AWAKIYKKELFDDIRFPVGKLFEDSAVMYLLFEKCEKIVYSNAKLYAYVHRDNSITTK
                     KFSDKDLDILDISNTILDHYSGNFRVYKAAVSYKVSACFRILLNSSSEKKYNQIQKDC
                     MTYILRNWRNVLFDKNVRLKNKLALISITLFNPFVKFIYSKVNRWE"
     gene            1538..>2606
                     /locus_tag="VXF95_002176"
     CDS             1538..>2606
                     /locus_tag="VXF95_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001045980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 61 protein"
                     /protein_id="HEV1082640.1"
                     /translation="MNKYEERYQEDLSKNDFEKLINRRYLSDKELQVEYVKKGTVLPP
                     KVFEMKLSNKLGLQKALHGKGGVVDSKGNYVELSEQKAVGMRNRVYGSYKFNHKNLAI
                     RNEKVIYLNYFINQWGHFLLDVVGRLWYPLLKDTDTKLDYTCYAGTETKLEGNYLEFL
                     ELLGIDKSRLILINRPTQFSEIIIPESSILPGEYYTKEYKMLFNSLVANVKLDNNLES
                     KKIYCSRARLDLAKGKEFGENGIEKVFLKNGYTPVYMETMSLKEQIRTLLSATTIVLT
                     SGSLAHNLLFINNKINVFILNKTYRVNLHQFLINKISEASVSFVDIYRSPLPILYGYG
                     PFLMDITKPLVNFFEDSGFTYD"
BASE COUNT          933 a          324 c          452 g          897 t
ORIGIN      
        1 tttttggatc gttgttcata gcggatttat taaatatata aagaaaaatc acagaccagt
       61 aattataacg acatggttag taatttcttt attatctata atattttttt tcaaacacat
      121 tataaataat agtgaatcct atactcatcg tgttttgggt attgttaatt tttttaaata
      181 ctacgaatct agcaaatttc atttattttt tggtgatgct gagttagcct ttggtgatat
      241 gacgaaaggt tatactcaca atataagaag tgttttaggt tgggatggaa ctgtggaaat
      301 gccgttgcta agtgttatga taaaaaatgg ttatgtcggc ttaatagggt atggagtagt
      361 cttatttaaa tttatatcct ctgtattatc tatggaagat agaagagtaa aaaatattgg
      421 cttatccatt ctaatacctc tacttctatc agcaatggtt gaaaattata tcgttaatat
      481 tagctttgta ttcatgccgg tctgtttttg tattttatgc tcaataaaaa atatagaatt
      541 taaaaataat tgaaagtgat ttatgaaaaa agtaagtatt attctacctg tctacaatgt
      601 tgaacagtat ataaaaaaat gcttagaatc aattcaacaa caaacttatc caaatttgga
      661 agtaatcatt gttaatgacg gagcaaccga taaaagcgtt gaatactgtg agcaaatttg
      721 taagatagat tctaggtttt ctgtcactca caaagaaaat ggtggacttt ccgatgcaag
      781 aaatgtcggt atagataaag ccaagggaga ttacctcatt tttgttgaca gtgatgattt
      841 tgtctctcaa gatatggtat cttatttagt atctagtatg gagaacaatg aggcagacat
      901 tgctatttgc gatcctgctc attattatag tgaccgtcaa aacaatgatc ttaatatttt
      961 ttatccggca tcaagcgtta aggtttacga aaaaacggaa gctctatgtg agatgtttta
     1021 tcaaaaatct tttttggtat ctgcttgggc taagatatat aaaaaggaac tatttgatga
     1081 tatcagattc cctgttggga agttatttga agatagtgct gttatgtatc tgctttttga
     1141 aaaatgtgaa aagatagtat attctaatgc gaaattatat gcctatgtgc atagagacaa
     1201 tagtattaca acaaagaagt tttcagataa agatttagat attttagaca tttcaaatac
     1261 tattcttgat cactatagtg ggaactttag agtttataaa gcggcagttt cctataaagt
     1321 ttcggcatgt tttagaattt tgttgaactc atcttcagaa aaaaaatata atcaaataca
     1381 aaaagattgt atgacatata ttttacgaaa ttggagaaat gtgttatttg ataaaaatgt
     1441 ccgattaaag aacaagcttg ccttgatttc tataactctt ttcaatcctt ttgttaaatt
     1501 tatctatagc aaagtaaaca gatgggaata atagcaaatg aacaaatatg aagaaagata
     1561 tcaggaagat ttatctaaga atgattttga gaaactaatc aatagaagat acctatcgga
     1621 taaagaacta caagttgaat atgtaaaaaa aggaacagtg ttacctccca aggtctttga
     1681 aatgaaacta tcaaataaac ttggtctaca aaaagctttg catgggaaag gtggtgttgt
     1741 agattcaaag gggaattatg ttgaactttc tgaacaaaaa gcagttggga tgagaaatcg
     1801 agtctatgga tcttacaaat ttaaccataa aaatttggct atcagaaatg aaaaagttat
     1861 ttacctaaac tatttcataa atcagtgggg acatttttta ctagatgttg tggggagatt
     1921 atggtatcca ttactaaaag atactgatac taaactggat tacacatgtt atgctggtac
     1981 agaaacgaaa cttgaaggaa actatttaga gtttttagaa ctcctcggta tagataaatc
     2041 acgcttaatt ttgataaatc gcccaactca attctcagag ataattatac ctgaaagttc
     2101 aattctgcca ggtgaatatt atacaaaaga atataaaatg ctttttaatt ctttagtagc
     2161 aaatgttaaa ttagataaca atttagaatc aaaaaaaatt tattgttcac gagctaggct
     2221 agatttagca aaaggtaaag agttcggtga gaatggtatt gaaaaggtct tcttaaaaaa
     2281 cggttatact ccagtttata tggaaacaat gtctttgaaa gaacaaataa gaacgctatt
     2341 atcagctaca acaatagtat taactagcgg ttcgttggct cataatttat tgtttataaa
     2401 caataaaatt aatgttttta ttttaaataa aacttataga gtaaatcttc accaattttt
     2461 aataaataaa atctcagaag ctagtgtgag ctttgtggat atttatcgtt ccccgttacc
     2521 tattttatat ggatatggtc catttttaat ggatattact aaacctttag tgaatttttt
     2581 tgaggacagt ggcttcacct atgatt
//
LOCUS       DAVLMQ010000120         2529 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000120 DAVLMQ010000000
VERSION     DAVLMQ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2529
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.121"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(69..926)
                     /locus_tag="VXF95_002177"
     CDS             complement(69..926)
                     /locus_tag="VXF95_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HEV1082641.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKIAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDSAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMVPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLTHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLTSHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            complement(1080..1814)
                     /locus_tag="VXF95_002178"
     CDS             complement(1080..1814)
                     /locus_tag="VXF95_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HEV1082642.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGISLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVMENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLRKVL"
     gene            complement(1814..2497)
                     /locus_tag="VXF95_002179"
     CDS             complement(1814..2497)
                     /locus_tag="VXF95_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HEV1082643.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAVKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
BASE COUNT          752 a          615 c          439 g          723 t
ORIGIN      
        1 tttaatattc atttctgcca ttttagatat agctatagaa aatacactct attaatcgaa
       61 tgtttctctt attttctatc caatgtccga agtgctgctt gataagtttg ctccatcagc
      121 atggtaatgg tcataggacc gacacctcca gggactggcg tgatatggct agtaagtggt
      181 gcaactgcct cataatcaac atctccacag agcttcccat tttcatctcg gttcatccca
      241 acgtcaatga caaccgcacc tggtttgaca aagtcagcag tcacaaactt ggcgcggccg
      301 attgcgacta caagaatatc tgctttagca gccaccttgg caagattatg agttcgtgag
      361 tgggtcaagg ttactgtcgc atttttagcc aaaagaagct gagccatagg ttttccaacg
      421 atatttgaac gaccgattac gaccgcattt ttaccttcca agtcaatccc atattcatga
      481 aacatttcca taattcctgc aggtgtcgag ggaaccatga ctggatgtcc agaccaaaga
      541 cgtcccatgt ttaggggatg gaaaccatcc acatcctttt ctgggtcaat ggctaataaa
      601 accgcctctt catcgatatg ttttggtaat ggcaactgga ccaaaatccc atgccaagct
      661 gaatcctgat tatatttagc aatcaggtct aacaattcct cttgagtaat ggtctctgga
      721 actcgcacta cttcgctacg ggaaccagcc gcaagagctg acctctcctt gttgcgaacg
      781 tagacttggc tggctggatt atccccaacc aaaatcacta ccaaaccagg cactagagct
      841 gtttcttcct ttaattttgc aatcttttca gccaactgcc cctgcaattt ggccgctaaa
      901 gcttttccat caataatctg tgtcatatca cttctctttt ctttcaaata tcttccatta
      961 taccaaaaac tgctagtgcc ctctaacact tctttcctag gttatcctat agtttcaaac
     1021 tataagaaaa agctctggtt gaacttttca ctaatcttgt cttgaaattt taaaatagat
     1081 tataaaacct ttctcaagaa atctttagtc cgttgttctt gggtttgttc aaaaatctgc
     1141 tcaggtgtcc catcttcaac aaccacaccg tctgccataa agataacacg atctgccacc
     1201 tcacgggcaa atcccatctc atgtgttacg ataaccatag tcatccctga cttggcaagg
     1261 tcttgcataa cagccaatac ctcacctacc atttcaggat ccaaggctga agttggttcg
     1321 tcaaagagca aaacatctgg ttccatagcc aacccacgcg cgatggcaat ccgttgttgt
     1381 tgcccacccg acagactctg tggataagcg tctgccttat ctggcaaacc aactttttcc
     1441 aaaagctctt gggctctctt ctcagcaact tccctgcttt cacctttagt cttgataggt
     1501 gacaaggtaa tattttccat cacagtcata ttaggaaaga ggttaaattg ttggaaaacc
     1561 atgcccatct tctcacgcat ggcaaacagg tcattcttct tgtccgtaat atcgactccc
     1621 tcaaagataa ccttcccctt ggttgcttcc tccaacaaat tcatagagcg aagcaaggta
     1681 gatttcccac tccctgaagg accgatgata acgacaactt ctcctctttt aatctcgagg
     1741 ctgatgccct tcaatacttc attctttcca aaagatttat gtaaattttc aatttttatc
     1801 aaggtttctg tcattatttc ttatctcctt gtcccatatg tttttcaaaa gctttcaagg
     1861 ctactgtcag aatagaggtc ataatcaagt agtaaaatgc tgcaaataaa agtggtgtta
     1921 aaggtagata ggttgttgta gaaactgttg tagccccatt ccacaactcc atgaccccaa
     1981 tagctgataa gagggagctg tccttgataa tggtgataaa ttcgttcccc aatgctggca
     2041 agatattttt gactgcttgt ggcaaaatca cataacgcat cgcattttta ggacgaatcc
     2101 ctagcgaata agccgcctct agctgacctt ttggaaccgc attgattccg gcacgaacag
     2161 tctccgaaac ataagcacca ctattcatag agataatcaa aatccctgga atcagacgcg
     2221 aaaaatcaac acctaaaatt ccaatctgaa tagtcggagc attgatatgc ataagagcaa
     2281 aggcaatcat aatttgaacc atcatcggtg tcccacggaa aatccaaacg tacaagttgg
     2341 ccaaccaaac aagcggttta aactttgaac gttgcccaaa agccaagaca acacccaaaa
     2401 tagttcccaa aaagataaca cagatagaaa taagaatcgt cacaacagcc ccatagttaa
     2461 aataaggtaa atacttaggt aaaaaagaaa aattcatagt cacactgctt tctaaaatag
     2521 aatactgta
//
LOCUS       DAVLMQ010000121         2418 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000121 DAVLMQ010000000
VERSION     DAVLMQ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2418)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2418)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2418
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.122"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            107..1114
                     /locus_tag="VXF95_002180"
     CDS             107..1114
                     /locus_tag="VXF95_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HEV1082644.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKQISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            1117..1317
                     /locus_tag="VXF95_002181"
     CDS             1117..1317
                     /locus_tag="VXF95_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HEV1082645.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            1469..1651
                     /gene="rpmF"
                     /locus_tag="VXF95_002182"
     CDS             1469..1651
                     /gene="rpmF"
                     /locus_tag="VXF95_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HEV1082646.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            1667..1816
                     /gene="rpmG"
                     /locus_tag="VXF95_002183"
     CDS             1667..1816
                     /gene="rpmG"
                     /locus_tag="VXF95_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HEV1082647.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(2295..>2418)
                     /locus_tag="VXF95_002184"
     CDS             complement(2295..>2418)
                     /locus_tag="VXF95_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HEV1082648.1"
                     /translation="ATGWFTVSGQWYYTYNSGDLLVNTTTPDGYRVNANGEWVG"
BASE COUNT          804 a          460 c          445 g          709 t
ORIGIN      
        1 aagaaattat tgggctgaaa ctttttagtg attattttca actttctatt gacttttaaa
       61 aacaaagtga tatcatttag atatcaaata ataggaggtc attcttatga ctgaaaaact
      121 catcaattca aaaccaaatg gtgtattcgc attgattctc attgaattga caatcgtact
      181 tggtatcttt atatttataa tgggtgttgg ttcggaaaac atttttggaa ttattatcgg
      241 acctttacta atcgtaattg caggtctagc tcatgctggt ttaaaagttg tcaaacctca
      301 ggaagctctg gttctgacac tctttggtaa ttatacaggt accatcaaag aacctggttt
      361 ttactttgtc aatcccttca gcgtagcagt caaccctgca aaccacactc gacttggaca
      421 aagtggtgat gttagcacaa aatctccttt tttaggagct aaatcatcaa atgacaatga
      481 tgtaaatctt gaaattggca agaaacagat ttccctcaaa gtcatgacct tgagcaattc
      541 tcgtcaaaaa atcaatgatt gcttaggaaa ccctgtagaa atcggtatcg cggtaacttg
      601 gagagttgtc gataccgcta aggcagtctt caacgttgat aactacaaag aatatctttc
      661 attgcaatgt gatagcgccc tccgtaatat tgtccgcatc tatccttacg atgtgtctcc
      721 taatgtggat actacgggtg acgggcaagc agatgaaggt agtctccgtg gctctagcga
      781 aattgttgct aaccgtattc gtgaagaaat ccaaagtcgt gttgaggatg ctggcttgga
      841 aatccttgaa gcacgtatca cttacctagc ttatgctcca gaaattgctg ccgttatgct
      901 tcaacgccaa caagcatctg ccattattga tgcacgtaag atgattgtag atggtgctgt
      961 aggaatggtt gaaatggcac tagaacggct caatgaaggg gaattggtag aacttgacga
     1021 agaacgaaaa gctgccatgg tttcaaatct ccttgtcgtt ctttgtggca atcatgatgc
     1081 acaaccaatt gtcaacacag gaagtcttta ctaaagatgg ctgaagctaa aaaaaagcag
     1141 atcccccttc gactctcaac aaagttatac gctgcactcg catcatgggc agaagacgac
     1201 tttcgttcag tcaatgggca aatagaatat ctcctcacag agtgtgtcaa gcaacggaaa
     1261 aaagacggaa aatacgtatc agaaaccatt gacgaaccat ttgagattga tatttaacac
     1321 cttctcctgt ctgccgtgtc ggataggaga attttttcat ctttttttgt caagtaactt
     1381 tactttacaa aaaaaatgtg ttatcctagt atggttgatg aaaatcagta gattgaatcg
     1441 aatataaata cctaaaggag aaatcaaaat ggcagtacct gcacgtcgca cttcaaaagc
     1501 gaagaaaaac aaacgtcgta cacactacaa agtaacagct ccatctgtaa actttgacga
     1561 aactactgga gattactcac gttctcaccg tgtatcactt aaaggatact acaaaggacg
     1621 taaaatcgct aaagctgcat cagctgaata atagaaggga gatactatgc gcgtaaatat
     1681 tacacttgaa cacaaagaat ctggtgaacg cttgtacctt acttctaaaa acaaacgtaa
     1741 cactccagac cgccttcaat tgaagaaata ctcaccaaaa cttcgcaaac acgttgtgtt
     1801 tacagaagtg aagtaagcat tcaatacgaa tcaatacaga agaaaaacgc ttgatcagcg
     1861 ttttttcttt ttgttaattt cactatattg caagggaaat cattcgaatg actacattat
     1921 tgaaataaga atacggattc ggacaattaa aagcaagagg aactcaaatg taagttgggg
     1981 ttcctttttt gtatattttt caaataacgc ctctacacta tttgtagcaa attcaccaac
     2041 tacagttgta tcttagttaa aataagttag aatatgtaag tgagtaccag atataccaag
     2101 acatcgtcac catctaaggt atattcaaaa tacaaaagtt gaccaactag atttctgaat
     2161 atccttatat atccattctt aaaattggtt taaatagcgt agtcttttaa actagttttg
     2221 agaatccaaa aaatcttcct acatatgtaa gaagattttt tagttcagaa tgattagatt
     2281 tagctaatgg atacctatcc tacccactca ccgttagcat tgactcgata gccatcgggt
     2341 gtagtcgtgt ttactaataa atctcctgaa ttataggtat agtaccattg accagaaact
     2401 gtaaaccaac cagtagcc
//
LOCUS       DAVLMQ010000122         2415 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000122 DAVLMQ010000000
VERSION     DAVLMQ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2415
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.123"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..440)
                     /locus_tag="VXF95_002185"
     CDS             complement(<1..440)
                     /locus_tag="VXF95_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HEV1082649.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKH"
     gene            562..1308
                     /locus_tag="VXF95_002186"
     CDS             562..1308
                     /locus_tag="VXF95_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HEV1082650.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     HQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            1321..2301
                     /locus_tag="VXF95_002187"
     CDS             1321..2301
                     /locus_tag="VXF95_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HEV1082651.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDTNMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
BASE COUNT          864 a          291 c          459 g          801 t
ORIGIN      
        1 taatgtttta ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca
       61 tgatcaacaa aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt
      121 aagatggctt tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct
      181 ccaccggatt cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca
      241 gtcttttctt caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt
      301 ttcattcttt gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa
      361 aaaacagttg tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata
      421 attcctttag atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa
      481 cgaaagaaaa acaattacga acgaaagttt aatttgttgt tttttgcttt ttattttggt
      541 agaataaaac ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa
      601 tatgaaaaga tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt
      661 agaaaagatt tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct
      721 gtattaaata gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga
      781 aaaattgttc aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct
      841 ggatcgacct gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt
      901 gtaacaaatt cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt
      961 gttcttggtg gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa
     1021 atgatacaga cttttcatgt gcatcaagct tttgttggga cagatggtta cgataaagag
     1081 atgggcttta caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg
     1141 tcggataaag tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga
     1201 agatttgctt taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat
     1261 atagctacat tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaaatgt
     1321 atgaatcaag ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac
     1381 ttaaatcagt cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg
     1441 ttaacagaag caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgataccaat
     1501 atgtttaagt tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt
     1561 ccaaatgaat ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca
     1621 ggtgtcctta ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt
     1681 ttaagtaatt tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct
     1741 ctagcaggtg gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa
     1801 atgtctagaa aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat
     1861 aaattgttag cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg
     1921 aaagatttag atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa
     1981 tggttagaca tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga
     2041 gaaatttgtt gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa
     2101 agaacgatag caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct
     2161 tacggtgata cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat
     2221 ttgattacag acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt
     2281 agagagattc taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag
     2341 ttgattgcac atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac
     2401 aactttatta tgtag
//
LOCUS       DAVLMQ010000123         2388 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000123 DAVLMQ010000000
VERSION     DAVLMQ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2388
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.124"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..236
                     /locus_tag="VXF95_002188"
     CDS             <1..236
                     /locus_tag="VXF95_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HEV1082652.1"
                     /translation="KVSSVLDGYVISCEVKMMKPQKEIYLSLVNKYQLDIKDCIFLDD
                     LEENVEAARTLGIKAFQIKERKEISNILKDLLN"
     gene            246..2273
                     /locus_tag="VXF95_002189"
     CDS             246..2273
                     /locus_tag="VXF95_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HEV1082653.1"
                     /translation="MVTIKDIARVSGVSHGTVSNVLNKKGNVSAAKIKLVEETAKKLG
                     YNMNSQAQFLRKGASSKCFFLLFNNARKKYAEYFAEIDQLSLDVEYVYLHKFSEIKNK
                     ISAILSENPQFIVCLGFSPKRFVDIEDNIPIFEVDTYQSNKTLSSFDSDKIFEIVLEL
                     VRTEKLSNLYFISLTNEKEHSLFEYLTQKIKNSTHIQVQERLQLLSLYPTLKNFAKYD
                     CIFVDDEDLMHTLLDLFDWFTIIDRPKICLIGSRVWFEKRNLFYIHLDYRILALNTAE
                     NLESGNSSIVPVKDGKQILIDQLFDGECDDIYLLTVHSPMNKALEILSEKYKQISGKN
                     IKIIEKRYDELLEMIESGDVSSSFDMIRMDMAWLPTFGKKYFQEITSFRQTKSINQNI
                     SKSVSREYMYIDQKQYTFPLDVSSQILVYRKDLFEDSFLQRRYFEKTKRKLTVPKSYQ
                     EFDELSEFFTLTENPFSPTLYGHSLALSSSVRAACEFIPRFRERLAQSRMNLAVLPQV
                     LTEYEKSYQFTEKSFNSSWNDFVTNLNSGKTSMEIIFSNYTSPLFDGLNVSAQFEFAT
                     ATIPGNTPVIGGGSIGISKYSNRVEECLNFINWLYSEEISILLTSLGGFLPSKYVMQN
                     RMLQFQYPWLSSLEDTFSIGSRTKWYGFNTDFRFEQMLGQELIESVKHRYG"
BASE COUNT          861 a          284 c          394 g          849 t
ORIGIN      
        1 ctaaagtatc atctgtttta gatggttacg taatttcttg tgaagttaaa atgatgaaac
       61 cacaaaaaga aatttacttg tcattagtta ataaatatca attagatata aaagattgta
      121 tatttttaga tgatttagaa gaaaatgtag aagctgcaag aactctaggt attaaagcat
      181 ttcaaattaa agagcgtaaa gagatctcaa atatactaaa agatctctta aactagaggt
      241 taattatggt tacaataaaa gatattgcaa gagtgtctgg agtctcacat gggacagttt
      301 caaacgtttt aaataaaaaa ggtaatgtct cagcagctaa aataaagtta gtagaagaga
      361 ctgcgaaaaa attgggttat aatatgaatt ctcaagctca gtttcttcga aaaggcgctt
      421 ctagtaaatg ttttttcttg ttatttaata atgcacgcaa aaagtatgct gagtattttg
      481 cagaaattga tcagttatct ttagatgtag aatatgttta cttacataaa ttctcagaga
      541 ttaaaaataa gatatctgca attttaagtg aaaatcctca atttatagtt tgcttaggtt
      601 tttctccaaa aagattcgtt gatattgaag ataatattcc gatttttgaa gtagatacat
      661 atcaatctaa taaaacttta tcttcctttg atagtgataa aatatttgag attgtacttg
      721 agttggttcg gactgaaaag ctatctaatt tatattttat ttcacttact aatgaaaaag
      781 aacattcttt atttgaatat ttaactcaaa aaataaaaaa ctcaactcat atacaagtgc
      841 aagaacgttt acaattgttg tctctatatc ctactctaaa aaactttgca aagtatgatt
      901 gtatatttgt tgatgatgaa gatttgatgc acacgctatt agacttattt gattggttta
      961 ctataattga tagaccaaaa atatgtttga taggttcacg tgtttggttc gaaaaaagaa
     1021 atctttttta tatacattta gattatagaa tattggcact caatactgcc gaaaatttag
     1081 aaagtggaaa tagttcaatt gtaccagtta aagatggcaa acaaatttta attgatcaat
     1141 tatttgatgg agaatgtgat gatatttatt tacttactgt ccattcacca atgaataaag
     1201 ccttagaaat tttatcagaa aagtataaac aaatttctgg gaaaaatatt aaaattatcg
     1261 agaaaagata tgatgaactt ttggagatga ttgagtctgg cgatgtttca tccagttttg
     1321 atatgattag aatggatatg gcttggcttc caacatttgg gaaaaagtat tttcaagaga
     1381 ttacaagctt tagacaaaca aaaagtatta atcaaaatat ttctaagtcg gtgtctcgag
     1441 aatatatgta tattgatcag aagcagtata cttttccatt ggatgttagt agtcagattt
     1501 tagtatatag aaaagactta tttgaagatt catttttaca aagacgatac tttgaaaaaa
     1561 caaaaagaaa attaactgta ccaaaaagtt atcaagagtt tgatgagtta agtgaatttt
     1621 ttacattaac agaaaatcca ttttcaccta cactttatgg ccatagttta gctttaagtt
     1681 cttcagtgag agcagcatgt gaatttattc ctcggtttcg tgagagatta gcacaatcta
     1741 gaatgaatct tgctgtactt cctcaggttt taactgagta tgagaaaagt tatcagttta
     1801 ccgaaaaatc atttaattct tcgtggaacg atttcgttac gaacttaaac agtggtaaaa
     1861 cttcaatgga aataattttt tcaaattata ctagtccatt atttgatggt ctcaatgttt
     1921 ctgctcagtt tgagtttgca actgccacta tacctggtaa tactcctgtg ataggtggtg
     1981 gctcaattgg aatttctaaa tattcaaata gagtggaaga atgtctaaac tttattaatt
     2041 ggttatattc tgaagagatt tctattttac taacatctct gggtggtttt ttaccatcaa
     2101 agtatgtcat gcaaaatagg atgttacaat ttcaataccc atggttatct agtttagaag
     2161 atacatttag tattgggagt agaacaaaat ggtacggctt taatactgat tttagatttg
     2221 agcagatgtt agggcaagag ttaatagaaa gtgtgaagca tagatatgga taaattaata
     2281 ctaaattttt attactagtt tatttattat tgtttaaaat taaagattca agtaaacacc
     2341 aattatattt aaaattatta ttttgacatt tttctattgc aaagttat
//
LOCUS       DAVLMQ010000124         2190 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.125, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000124 DAVLMQ010000000
VERSION     DAVLMQ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2190
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.125"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..627
                     /locus_tag="VXF95_002190"
     CDS             <1..627
                     /locus_tag="VXF95_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HEV1082654.1"
                     /translation="ITMDMFSPYYDLARQLFPCAKIVLDRFHIVQHLSRAMSRVRVQI
                     MNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKRFYRPTFRMHLTNKEILNKLLSYSEDL
                     KHHYQLLLFHFQNKEPEKFFELIEDNLKQVHPIFQTVFKTFLKDKEKIINALQLPYSN
                     AKLEATNNLIKLIKRNAFGFRNFENFKKRIFIALNIKKERTKFVLSRA"
     gene            complement(761..848)
                     /locus_tag="VXF95_002191"
     tRNA            complement(761..848)
                     /locus_tag="VXF95_002191"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(812..814),aa:Ser,seq:gct)
     gene            complement(855..928)
                     /locus_tag="VXF95_002192"
     tRNA            complement(855..928)
                     /locus_tag="VXF95_002192"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(892..894),aa:Ile,seq:gat)
     gene            complement(964..1034)
                     /locus_tag="VXF95_002193"
     tRNA            complement(964..1034)
                     /locus_tag="VXF95_002193"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1000..1002),aa:Gly,seq:tcc)
     gene            complement(1054..1126)
                     /locus_tag="VXF95_002194"
     tRNA            complement(1054..1126)
                     /locus_tag="VXF95_002194"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1091..1093),aa:Phe,seq:gaa)
     gene            complement(1130..1203)
                     /locus_tag="VXF95_002195"
     tRNA            complement(1130..1203)
                     /locus_tag="VXF95_002195"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1167..1169),aa:Met,seq:cat)
     gene            complement(1217..1306)
                     /locus_tag="VXF95_002196"
     tRNA            complement(1217..1306)
                     /locus_tag="VXF95_002196"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1268..1270),aa:Ser,seq:tga)
     gene            complement(1317..1390)
                     /locus_tag="VXF95_002197"
     tRNA            complement(1317..1390)
                     /locus_tag="VXF95_002197"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1354..1356),aa:Ile,seq:cat)
     gene            complement(1404..1477)
                     /locus_tag="VXF95_002198"
     tRNA            complement(1404..1477)
                     /locus_tag="VXF95_002198"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1441..1443),aa:Met,seq:cat)
     gene            complement(1483..1556)
                     /locus_tag="VXF95_002199"
     tRNA            complement(1483..1556)
                     /locus_tag="VXF95_002199"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1520..1522),aa:Pro,seq:tgg)
     gene            complement(1572..1645)
                     /locus_tag="VXF95_002200"
     tRNA            complement(1572..1645)
                     /locus_tag="VXF95_002200"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1609..1611),aa:Arg,seq:acg)
     gene            complement(1655..1740)
                     /locus_tag="VXF95_002201"
     tRNA            complement(1655..1740)
                     /locus_tag="VXF95_002201"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1704..1706),aa:Leu,seq:taa)
     gene            complement(1748..1819)
                     /locus_tag="VXF95_002202"
     tRNA            complement(1748..1819)
                     /locus_tag="VXF95_002202"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1785..1787),aa:Gly,seq:gcc)
     gene            complement(1842..1914)
                     /locus_tag="VXF95_002203"
     tRNA            complement(1842..1914)
                     /locus_tag="VXF95_002203"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1879..1881),aa:Thr,seq:tgt)
     gene            complement(1933..2014)
                     /locus_tag="VXF95_002204"
     tRNA            complement(1933..2014)
                     /locus_tag="VXF95_002204"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1978..1980),aa:Leu,seq:tag)
     gene            complement(2020..2092)
                     /locus_tag="VXF95_002205"
     tRNA            complement(2020..2092)
                     /locus_tag="VXF95_002205"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2057..2059),aa:Lys,seq:ttt)
     gene            complement(2117..2189)
                     /locus_tag="VXF95_002206"
     tRNA            complement(2117..2189)
                     /locus_tag="VXF95_002206"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2154..2156),aa:Asp,seq:gtc)
BASE COUNT          644 a          563 c          435 g          548 t
ORIGIN      
        1 attactatgg atatgtttag tccttactat gacttagcta gacaactttt cccatgtgct
       61 aaaatcgtgt tggatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg
      121 cgtgttcaaa tcatgaatca gtttcatcga aaatcccatg aatacaaggc tatcaagcgc
      181 tactggaagc tcatacaaca ggatagtcgt aaactgagtg ataagcgatt ttatcgtcct
      241 acttttcgta tgcacttaac caataaagag attttaaaca agcttttgag ttattcggaa
      301 gacttgaaac accactatca gctcttactt tttcacttcc agaataagga accagagaaa
      361 tttttcgaac ttattgagga caatcttaag caggttcatc ctatttttca gactgtcttt
      421 aaaaccttcc tcaaagataa agaaaagatt attaacgccc ttcaactacc ctattctaat
      481 gccaaactgg aagcgaccaa taatctcatc aaacttatca agcgcaatgc ctttggattt
      541 cggaactttg aaaacttcaa aaaacggatt ttcatcgctt tgaacatcaa aaaagaaagg
      601 acaaaatttg tcctttctcg agcttagctt ttcttcaacc cactacagtt gacaaagagc
      661 cataaaaata acttcagatt agtaattcaa ttaagtttta cggatctgaa gctttattgt
      721 ctctaaaaat aaaaaagaga gttacaaact ctcattaaaa cggagaataa gggattcgaa
      781 cccttgcgcc agttacccga cctaacgatt tagcaaaccg tcctcttcag cctcttgagt
      841 aattctccaa ttaatgggca cgagtggact cgaaccaccg acctcacgct tatcaggcgt
      901 gcgctctaac cacctgagct acgcgcccaa gttaaaaaac ttggtaattt gaacaaagtt
      961 caaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgta gttttaccac
     1021 taaactacac ccgcataaat actatcaata aaatggcgcg agacggaatc gaaccgccga
     1081 cacatggagc ttcaatccat tgctctacca actgagctac cgagccttat tgcgggagca
     1141 ggatttgaac ctacgacctt cgggttatga gcccgacgag ctaccgagct gctccatccc
     1201 gcgttaataa tataaaagga ggatgtggga ttcgaaccca cgcacgcttt tacacgcctg
     1261 acggttttca agaccgttcc cttcagccgg acttgggtaa tcctccaata ttcaaatgga
     1321 ccttgtagga cttgaaccta cgaccactcg gttatgagcc gagagctcta accagctgag
     1381 ctaaaggtcc aacaagatca ttatagcggc gaaggggatc gaacccccga cctcccgggt
     1441 atgaaccgga cgctctagcc agctgagcta caccgccatg aatcgggaag acaggattcg
     1501 aacctgcgac accttggtcc caaaccaagt actctaccaa gctgagctac ttcccgagtt
     1561 aaatagaaaa atgcacccta gaggagtcga acctctaacc gcctgattcg tagtcaggta
     1621 ctctatccag ttgagctaag ggtgctccat attatgccga ggaccggaat cgaaccggta
     1681 cgatcgttac caatcgcagg attttaagtc ctgtgcgtct gccagttccg ccaccccggc
     1741 ctctctaagc gaacgacggg attcgaaccc gcgaccccca ccttggcaag gtggtgttct
     1801 accactgaac tacgttcgca ctgttttctt ctatctaaaa atgccggcta catgacttga
     1861 acacgcgacc ctctgattac aaatcagatg ctctaccaac tgagctaagc cggctcattt
     1921 gttatatctt aatgcgggtt aagggacttg aacccccacg ccgttaagcg ccagatccta
     1981 aatctggtgc gtctgccaat tccgccaaac ccgcatatat gacccgtact gggctcgaac
     2041 cagtgaccca ttgattaaaa gtcaattgct ctaccaactg agctaacgag tctaaaataa
     2101 cttgcgttac cttaaacggt cccgacggga atcgaacccg cgatcttcgc cgtgacaggg
     2161 cgacgtgata accgctacac tacgggacct
//
LOCUS       DAVLMQ010000125         2163 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.126, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000125 DAVLMQ010000000
VERSION     DAVLMQ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2163)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2163)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2163
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.126"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..218)
                     /locus_tag="VXF95_002207"
     CDS             complement(<1..218)
                     /locus_tag="VXF95_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082655.1"
                     /translation="MSDNLKAYIFLLGFLILAGIAIFILPQGHFFSVSALVLGCIPLF
                     ISIYYFAKIKLLGFYELLKELLDKIKGI"
     gene            complement(248..1006)
                     /locus_tag="VXF95_002208"
     CDS             complement(248..1006)
                     /locus_tag="VXF95_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HEV1082656.1"
                     /translation="MKKIKASTWNINQRSGQGKQIPEMIVHELAKQNSEIVCLTEYVK
                     TDNPSLFCTKLQDMGYKIFEDVRTIDFGNQILIAIKNDLVNDCQVITIDNDDNNPNFL
                     HVRVTIEGQELNIIGVRIKVGGENIFQDFKHRKSQLDKLISNLPATHENTIVLGDFNN
                     GYFQQNDDIHSYQGKAREFYSYPLLKSEMNKAGLTVHTPSEETSWKYCKLDHIFANIP
                     ISNENYSWEFLKNADYNSRVGFPDHAILSASISL"
     gene            complement(1024..1256)
                     /locus_tag="VXF95_002209"
                     /pseudo
     CDS             complement(1024..1256)
                     /locus_tag="VXF95_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000982220.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1539..2000
                     /locus_tag="VXF95_002210"
     CDS             1539..2000
                     /locus_tag="VXF95_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082657.1"
                     /translation="METRNEKFRRLSEARMTKVFSILNILRNQSDKSKYTFSKSDIEE
                     LFGALEQKGEEIKEFFTSPITIKTINLKKSFHYSMVDTSNDKEVAFKKLSTARVEKIF
                     SLMNLLANLSNKSNYNYSDWEVEELFSAYDEEVRKCKVFFEEKRTVFKYSE"
BASE COUNT          753 a          310 c          363 g          737 t
ORIGIN      
        1 tagatacctt ttattttatc taaaagctct tttaaaagtt cgtaaaaccc taagagcttg
       61 atttttgcga aataatagat agaaataaat aatggaatac atccaagaac aagggcagaa
      121 actgaaaaga aatgcccttg aggaagaata aaaattgcta tgccagctaa tatcagaaat
      181 cctaaaagaa atatatatgc ttttaaatta tcactcattt tgcattacct cctctaataa
      241 acaagtacta taaagagata gaggctgata gaatagcatg gtctggaaag ccgactcggc
      301 tattataatc agcatttttt aagaattccc aagaataatt ttcatttgat ataggaatgt
      361 ttgcaaaaat atggtctaat ttacaatatt tccaagaggt ttcctcagag ggagtatgta
      421 cggttaggcc tgctttattc atttcagact taagcaatgg ataagagtaa aactccctag
      481 ctttgccctg ataggaatga atatcgtcat tctgttggaa atatccatta ttaaagtcac
      541 ccagcacaat tgtattttca tgtgttgcgg gtaaatttga gattagtttg tctagttgcg
      601 attttcgatg tttgaaatct tgaaaaatgt tttctccacc gaccttgata cgaactccaa
      661 taatgtttaa ttcttgtcct tcaattgtca ctctaacgtg taaaaagttt ggattattat
      721 catcattatc gatagtaatg acttggcaat cattaactaa atcattcttt attgcaataa
      781 ggatttgatt tccaaaatca atagtacgca catcttcaaa aattttgtat cccatatcct
      841 gtaatttagt acagaataaa ctaggattat ctgtttttac atattctgtc aagcagacga
      901 tttctgaatt ttgtttagct aattcatgta caatcatttc aggaatttgt tttccttgtc
      961 ctgaacgttg attgatattc caagtggatg ctttaatttt tttcatatat aaacctttct
     1021 atgttctgct ttactaacgt aaagaagatt tattagatga ttgtttgcaa taacaaggta
     1081 aacaagattt cctgttctgg tttcatactc atttactagc tctctataat gtgctttatc
     1141 agtgtctatt tttcccattg attagtgaga ctagggctga gtgcaaaaac ggtatcaaga
     1201 gtatctaatc tatctcgtgc ttcttgatat tgttcagttt ttaatgtatt catcattttg
     1261 tcctctcttt aatgttaatt gagggagcaa atgctcctgt gtgatgtatg agtgaaatga
     1321 ggaagtgcta gaagttgtat ccatcataga tttctccaag ttctgtaaat ataagaatcc
     1381 tcctttttgt atagtatatt tgtgggatat tcccctatgt ttggtattat actacagtta
     1441 aataaaaaaa tcaacaacaa agatgcaata tttgaaaaaa atctctccat atgataaaat
     1501 ttaatgtata gcaatggtag gtaatgttag gagaaacaat ggaaactaga aatgaaaaat
     1561 ttagaagatt atcagaagct agaatgacta aggttttttc aattttaaat atattgagaa
     1621 atcaaagtga caaatcgaaa tacacttttt caaaatcaga cattgaggag ctatttggag
     1681 cgttagaaca aaaaggtgaa gaaataaaag agtttttcac tagccctatt acgataaaaa
     1741 caatcaatct aaaaaaatct tttcattatt ctatggttga tacaagtaat gataaggaag
     1801 tagcttttaa gaaattatca actgcaaggg tagaaaaaat tttttcacta atgaatttac
     1861 ttgcaaatct tagcaataaa tcgaattata attatagtga ttgggaagtg gaagaattgt
     1921 tttcagctta tgatgaagaa gtaagaaaat gcaaagtatt tttcgaagaa aagagaacag
     1981 tatttaaata tagtgaataa gtcaggaata ctaaagtgtt actaaaaata aaaaaactat
     2041 cgtttttgtg atagaggtaa ctttttgaaa aggctatttg actggcttta tatacttatg
     2101 aaatgttaag agcccaactc aaaatccagt gtccgcaagg acgtgccggt tcgaccccgg
     2161 ccg
//
LOCUS       DAVLMQ010000126         1918 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.127, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000126 DAVLMQ010000000
VERSION     DAVLMQ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1918)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1918)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1918
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.127"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(186..1817)
                     /locus_tag="VXF95_002211"
     CDS             complement(186..1817)
                     /locus_tag="VXF95_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HEV1082658.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFISAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
BASE COUNT          594 a          373 c          399 g          552 t
ORIGIN      
        1 taataacagg acaaatcgtt caggacagtc aaatcgattt ctaacaatgt tttagaaata
       61 gaggtgtact attctagttt caatatatta tatatctgca gaatactctt tcagtttcat
      121 tcagcctagt cttgcttagg aaaaagtaag aagccatcca attatgatgg atagcttctt
      181 ggttattaga tttgttctgc aaaaaccttt tcagcaaggt tcatagcgtg gtctgataca
      241 cgagtgtagt gtgagatgat gtcgataaag ttgaccccag cttgtgttga acattcgcct
      301 ttgttgaggc gtttgatgtg ggtttttctg agaacacgtt ctatcttatt gattgcttca
      361 tgacgttcta caagactgcg tgctttttca atatcattgt tttccacact atccagagca
      421 tctttgataa agtcactagt ttggcggtaa acttcctcta attctttcaa ggcggcatca
      481 gaaaattcaa catttttccg ttgaagatag tcagtcagat tgagtagagc ctccgtgtgg
      541 tctccaatcc gttccaaatc acgggaggaa tcaaggatat tggtaagcac ttcactttct
      601 ttttggctga gagcttcgct tgaaagggca atgagataac gtgttaattg ctcatcgatg
      661 gtgttaattg cttcttcggt tttatgccct ttttcagcaa ctttttcatc caagtcaatg
      721 atgtacttat aggaaaggtc aaaggcttta gcagcgtagt ttcctaagtg caagagctct
      781 ttcttagcat ttcctagagc gatagatggg gcctgtttga tgaaatgttc atcaagatat
      841 aagggttcgt atttgacaac ctcgtcctct ccaggaataa tcttggttac aaagtaagcc
      901 agagctccga taaatggaaa ttggacaatg gtgttggtaa tattaaaggt tccgtgagca
      961 aaggcgatgg tcatttccgg tgctagattt agcgtagctt caaaccaatg aatcaggaca
     1021 gtaaaaggaa ctagaaaaat aacgcagaca actgttccga taacgttgaa ggcaacatga
     1081 gctcctgcta cccgtttagc tgcaatatta gcccctaaag aggcaatgat ggctgtaatg
     1141 gttgtcccga tattgtcacc aaatagaact ggcaaagctc cctgtagatc aattagattg
     1201 ccggcgtaga ggttttgtaa aatcccaatg gtagccgaag aagcttgaat tagcaaggtc
     1261 aagccagtac cgacaaagac acccaaaaca ggattcttac ttagctcaat catatagtcc
     1321 ttaaagacct gtaaatcctt gagtggagcc attgcgccgc tcatgagatt gagggcaaaa
     1381 aagataccac cgacaccaaa gaggatgcgt ccgatattat tgactgtccg atttttcgta
     1441 aaaaaaagac agacggcact gataaagagc ataggtaggg catagttacc taatttaaaa
     1501 ccgatgagaa aggatgtgac agttgtccca atattagcac ccatgacaat cccgatagcc
     1561 tgacgtaagg ttaagagacc ggcactgacc aggccgactg tgataactgt tacaccagaa
     1621 ctagactgaa ttagagcagt catcccaata ccaaccagaa ctccaaagaa aggattacta
     1681 gtatatttgt caatgtaaaa acgaaggcga tctccagcag cttgttgtaa accgtctccc
     1741 atggtcttga tgctatataa gaatagcccc agaccaccta aaaagtgaaa taaaatttcc
     1801 tgccaattaa tggacatttc tttttcctcc gaaaaataat cgcggaatat ctcctattct
     1861 attttaaagg ataaaagtaa atctaacaag tgttaatgtc aagtttgtaa aagaaaat
//
LOCUS       DAVLMQ010000127         1894 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.128, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000127 DAVLMQ010000000
VERSION     DAVLMQ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1894
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.128"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(93..392)
                     /locus_tag="VXF95_002212"
     CDS             complement(93..392)
                     /locus_tag="VXF95_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HEV1082659.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
     gene            complement(557..1008)
                     /locus_tag="VXF95_002213"
                     /pseudo
     CDS             complement(557..1008)
                     /locus_tag="VXF95_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013080.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            1090..1894
                     /locus_tag="VXF95_002214"
                     /pseudo
     CDS             1090..1894
                     /locus_tag="VXF95_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="programmed frameshift; internal stop; incomplete;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          586 a          333 c          367 g          608 t
ORIGIN      
        1 gggggcagtt catttcggca cctgatacta tgcgttttgt tatggaaaga cttattggac
       61 tttctctcaa atcgagtttt tactcaattt tcttacttga ttgggattga aattccaatt
      121 aatttctctg agtagagtgt cttgatattg gcttcatcaa cagaggtctt atcaatttta
      181 cgtttcaaga aaaattcttg aatggtttcg atttcaggct cacgaatagc acggtgtttg
      241 tttgagatga ggatttcata gtgaagcgga gcttgggtaa aaataacatc tgtattccct
      301 gcagaataaa cctcaacaag ggttgcatcg gtactttcta gttgactttt tacaagttgc
      361 gagtgtgagt ttgtcgtatt gataagcttc ataatatttc ctccgatttt ctaattctat
      421 tataacactt tttgaataaa gtcgcttgat ttatactcaa tgaaaatcaa agagcaaact
      481 aggaagctag ccgcaggcta tacttgagta cggtaaggcg acgcttacgt gatttgaatt
      541 ttattttcga agagtattag ccaatcttat gctgtttttt ccaagattca atggcccatt
      601 tatggctgcc acgtttaagg tttttgatag cctcgtcaat agggaaccag gcaatatgat
      661 taaagttttc tagtggcttt tgtacttctt tgaaaggagt tgcttcatag aggtaggcag
      721 gattgtagta gtaggtatca cgatgacgag aatagaaata ttcgtcagct ggtccgtaat
      781 aggtaccaat ttctgctgtg aaaccaagct cttcaatcaa ctcacgcttt agggcttcct
      841 gatgattttc acctgcttca atttttccac atggtaggaa ccaagcacca tttggttctt
      901 gaacaagaac aatttgtttt tgttcaggat tagggataac tgcatatacg ccatagcgag
      961 caatatagtc tgtattcact ttttttctcc gaaagttggg tttgccattg cattttcctc
     1021 attatctagt atcgttatta ttatagtgaa atgaaccaaa aatagtacac aatgtggtat
     1081 aatcttctta tggcatattc aatagatttt cgtaaaaaag ttctctctta ttgtgagcga
     1141 acaggtagta taacagaagc atcacacgtt ttccaaatct cacgtaatac catttatggc
     1201 tggttaaagc taaaagagaa aacaggagag ctaaaccacc aagtaaaagg aacaaaacca
     1261 agaaaagttg atagagatag acttaaaaac tatcttactg acaatccaga cgcttatttg
     1321 actgaaatag cttctgaatt tggctgtcat ccaactacca tccactatgc gctcaaagct
     1381 atgggttaca ctcgaaaaaa agaaccacac ctactatgaa caagagccag aaaaagtagc
     1441 cttatttctt aagaatttta atagattaaa gcacctagca cctgtttaga ttgacgaaac
     1501 aggattcgat acttattttt atcgagaata tggtcgctca ttaaaaggtc agttaataag
     1561 aggtaaagta tctggaagaa gatatcagag gatttctttg gttgcaggtc taacaaatgg
     1621 tgagttaatc gctccaatga cttacgaaga gatgatgacg agcgactttt ttgaagcttg
     1681 gtttcagaag tttttcttac caacattaac cacaccatcg gttattatta tggataatgt
     1741 aagattccat agaatgggga agctagaact tttatgcgaa gagtttgggc ataaactttt
     1801 acctcttcct ccctactcgc ctgagtacaa tcctattgag aaaacatggg ctcatatcaa
     1861 aaagcacctc aaaaaggtat taccaagttg caat
//
LOCUS       DAVLMQ010000128         1776 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.129, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000128 DAVLMQ010000000
VERSION     DAVLMQ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.129"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>1776
                     /locus_tag="VXF95_002215"
     CDS             <1..>1776
                     /locus_tag="VXF95_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV1082660.1"
                     /translation="AKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESTRQ
                     ATAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDI
                     SSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGTDNQISNLKTQV
                     ATNKDNAERQMGRISDQVSANKANADSQFANVTNQLARKVETTDFQRVKETSKLYERI
                     LGNTENGIADKVARMALTNQLFQVEVGKYSVSGPNLIKNSDFKNATNEWGSTQNLGRL
                     VKHSFYHNGQKDLMRLSNATKNENFLYSHRFNLERNTDYVLNFRGFNNSALASYDVYI
                     LGRRAGESDGFTIVKKVVSSKKLSTSRCEDVSVTFNSGEMDNAYIRFDNNGSSSGTAD
                     LYITEVDLYKGYKPRTWQPHPEDAVADANKKLEATQTKMTQLAGSWVVENINSAGDII
                     SGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEA
                     VTAEKLKVDNALIKKLTATDAFIYELISKRIFSTKVESVISSSTFLEAYQGRIGGFTL
                     GQFDQGGGRWISGVNQFSVGMGNGAG"
BASE COUNT          575 a          330 c          407 g          464 t
ORIGIN      
        1 gctaaggcta cctttgagcg gacagctcag ggcttgcgaa ccgacttatc agctattcag
       61 gaatatgtaa ataaagacgg tcagcgacag gaagccctac agcgctatac tcgtgaggag
      121 agcacgagac aagcgacagc agtccgtgag ctggtcaatc gtgatttcgt tggtaaggct
      181 acttatcaag aagatgttaa gggtatcaat cagaggattg aagctgttaa aactagtgcg
      241 aataaagaca tcgctagtca aatcgctagc tatcgtcaat ctgtagatgg taagttcacg
      301 gatatttcaa gtcagataac tacttataag caagatgtgg gcggtcaaat cagtggtcta
      361 tcaaatagac ttacaagcag tgagcaagga accactactc agatttcaaa tctttcaaat
      421 cggataaaca gtaataagca aggcacagat aatcagattt caaatttaaa gactcaggtc
      481 gctacaaaca aggataatgc tgaacgacaa atgggtagaa tatctgatca ggtttctgca
      541 aacaaagcga atgctgatag tcaatttgcg aatgtgacca atcaactagc tcgaaaagta
      601 gagactactg acttccagcg tgttaaggaa accagtaaac tttacgagcg gattttgggc
      661 aatactgaaa atggaattgc ggataaggtt gctcgcatgg ctctgaccaa tcaattgttt
      721 caggttgagg ttgggaaata tagtgtaagc ggccctaacc tcattaagaa tagtgatttt
      781 aaaaatgcta cgaatgaatg gggctcaact caaaatttag gaagattggt taagcatagc
      841 ttttatcaca acgggcagaa agaccttatg cgtttaagta atgcaactaa aaacgaaaac
      901 tttttgtata gtcaccgttt taatcttgaa cgaaatactg actatgtact gaattttaga
      961 ggatttaaca acagtgctct cgcaagctat gatgtttata ttttgggacg aagagcaggc
     1021 gagagcgatg gattcacaat cgttaagaaa gttgttagca gcaagaaact atctacctct
     1081 agatgcgaag atgtctcagt aacttttaat tccggagaaa tggataatgc ttacattcgt
     1141 tttgataaca atggctcatc atcaggaaca gctgatttgt atattacaga agttgacttg
     1201 tacaaaggtt ataaacctag aacatggcaa ccacatccag aagatgcagt cgcagatgcg
     1261 aataagaagc ttgaagcaac gcaaacaaaa atgactcaac tagctggctc atgggtagtt
     1321 gaaaacatca actcggctgg agatatcatc tctggaatca atcttggcgc caatggacat
     1381 aaccgctttg ttgggaaatt gacccacatc actggagaga ccctgattga cagagcagtc
     1441 atcaagtctg ccatggttga taagctcaaa acggccaatt ttgaagctgg ttcggtcacg
     1501 actacgatat tagacgctga agcggtaact gctgagaagt tgaaagttga caatgcgctt
     1561 attaaaaaat taactgcaac tgatgctttt atttacgaac tgatatctaa acgtatcttc
     1621 tctactaagg ttgagtccgt catttctagc tcaaccttcc tagaagccta tcaaggccga
     1681 atcggtggat tcacacttgg tcaatttgac cagggtggcg gtcgctggat ttcaggtgtc
     1741 aatcagttct ctgttggtat ggggaatggt gccggg
//
LOCUS       DAVLMQ010000129         1776 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.130, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000129 DAVLMQ010000000
VERSION     DAVLMQ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1776
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.130"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>1776)
                     /locus_tag="VXF95_002216"
     CDS             complement(<1..>1776)
                     /locus_tag="VXF95_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HEV1082661.1"
                     /translation="AKATFERTAQGLRTDLSAIQEYVNKDGQRQEALQRYTREESTRQ
                     AIAVRELVNRDFVGKATYQEDVKGINQRIEAVKTSANKDIASQIASYRQSVDGKFTDI
                     SSQITTYKQDVGGQISGLSNRLTSSEQGTTTQISNLSNRINSNKQGADNQISNLKTQV
                     ATNKDNAERQMGRISDQVSANKANADSQFANVTNQLVRKVETTDFQRVKETSKLYERI
                     LGNTENGIADKVARMALTNQLFQVEVGKVAKGGRNYIRNGQFKNGSKNWLEYQSVNFG
                     LNFNYQHSQNPNNRNRPGLHFYHDSQDVANFFGIQQSFAFDGVRGEKVSVSLLVSKDG
                     GDSNSGLKVALHYIKNKNIIGQEWQNIPSPQITSKYKRFTFTFTLSDDVENLNLMLFG
                     EKGKTINLYVTDVQLERGSVATDYKEAPEDTDEAIRSVQSQLTGSWAVQNINSAGDII
                     SGINLGANGHNRFVGKLTHITGETLIDRAVIKSAMVDKLKTANFEAGSVTTTILDAEA
                     VTAEKLKVDNALIRKLTANDAFIDQLISKRIFSTKVESVISSSTFLEAYQGRIGGFTL
                     GQFDQGGGRWISGVNQFSVGMGNGAG"
BASE COUNT          475 a          407 c          337 g          557 t
ORIGIN      
        1 tccggcacca ttccccatac caacagagaa ctgattgaca cctgaaatcc agcgaccgcc
       61 accctggtca aattgaccaa gtgtgaatcc accgattcgg ccttgatagg cttctaggaa
      121 ggttgagcta gaaatgacgg actcaacctt agtagagaag atacgtttag atatcagttg
      181 gtcaataaaa gcatcatttg cagttaattt tctaataagc gcattgtcaa ctttcaactt
      241 ctcagcagtt accgcttcag cgtctaatat cgtagtcgtg accgaaccag cttcaaaatt
      301 ggccgttttg agcttatcaa ccatggcaga cttgatgact gctctgtcaa tcagggtctc
      361 tccagtgatg tgggtcaatt tcccaacaaa gcggttatgt ccattggcgc caagattgat
      421 tccagagatg atatctccag ccgagttgat gttttgaact gcccatgagc cagttagttg
      481 gctttgaaca gagcgaatcg cttcgtccgt gtcttcagga gcttctttgt aatccgtcgc
      541 gacagaacct ctttcgagtt gaacatctgt aacatagagg ttgatggtct tccctttttc
      601 accaaacaac atcaaattca gattctctac atcgtctgat aaagtaaacg taaatgtgaa
      661 acgcttatac ttcgatgtta tttgtggact tgggatattt tgccactctt gcccaataat
      721 gtttttgttt ttgatgtagt gcaaagcgac tttcaagcca ctgttgctat cgccaccatc
      781 tttcgaaaca agaagagata cactcacttt ctcacctcga acaccatcaa atgcaaaaga
      841 ttgctgaatt ccaaaaaaat tagcaacatc ttgagaatcg tgatagaagt gtagtcctgg
      901 acgatttcga ttattaggat tttgagagtg ttgatagttg aaattcaaac caaaattaac
      961 agattgatat tcaagccagt ttttcgaacc gttcttaaat tgaccatttc tgatataatt
     1021 tcgaccacct ttggcaacct tcccaacctc aacctgaaac agttgattgg tcagagccat
     1081 gcgagcaacc ttatccgcaa ttccattttc agtattgccc aaaatccgct cgtaaagttt
     1141 actggtttcc ttaacacgct ggaagtcagt agtctctact tttcgcacta gttgattggt
     1201 cacattcgca aattgactat cagcattcgc tttgtttgca gaaacctgat cagatattct
     1261 acccatttgt cgttcagcat tatccttgtt tgtagcgacc tgagtcttta aatttgaaat
     1321 ctgattatct gcgccttgtt tattactgtt tatccgattt gaaagatttg aaatctgagt
     1381 agtggttcct tgctcactgc ttgtaagtct atttgaaagg ccactgattt gaccgcccac
     1441 atcttgctta taagtagtta tctgacttga aatatccgtg aacttaccat ctacagattg
     1501 acgatagcta gcgatttgac tagcgatgtc tttattcgca ctagttttaa cagcttcaat
     1561 cctttgattg atacccttaa catcttcttg ataagtagcc ttaccaacga aatcacgatt
     1621 gaccagctca cggactgcta tcgcttgtct cgtgctctcc tcacgagtat agcgctgtag
     1681 ggcttcctgt cgctgaccgt ctttatttac atattcctga atagctgata aatcggttcg
     1741 caagccctga gctgtccgct caaaggtagc cttagc
//
LOCUS       DAVLMQ010000130         1765 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.131, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000130 DAVLMQ010000000
VERSION     DAVLMQ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.131"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..262
                     /locus_tag="VXF95_002217"
     CDS             <1..262
                     /locus_tag="VXF95_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HEV1082662.1"
                     /translation="QNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQ
                     FGENKYRLLNRKYEMDGINALHPEDLIDYQKVFLNHHINCYF"
     gene            595..978
                     /locus_tag="VXF95_002218"
     CDS             595..978
                     /locus_tag="VXF95_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HEV1082663.1"
                     /translation="MIHKIRFEHFSYDIVCPETVDNQPIPKLFLLPLVENAIKHGMQY
                     RIDLHIDIHITLEADSLTFLVKDNAGGLTKQERFAILDSLESPHTQHGIMNSYKQLSN
                     FFSDVQLDLGVNRQGETWVKFVTKD"
     gene            982..1209
                     /locus_tag="VXF95_002219"
     CDS             982..1209
                     /locus_tag="VXF95_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV1082664.1"
                     /translation="MFKLIIVEDEHLIRKWLEIAVDYSALGIQVVGTASHGQEGMKLI
                     QEKETHICLNRHHNANYGCFYDVQSHSYSFL"
     gene            1258..1491
                     /locus_tag="VXF95_002220"
     CDS             1258..1491
                     /locus_tag="VXF95_002220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HEV1082665.1"
                     /translation="MQYGAVDFLSKPIDTKELTECLQKIVLRLQISTSQETPFLEEYQ
                     TLLTSIQQVDTQNQIIQQIISFVHKHYAEHYYC"
     gene            1590..1733
                     /locus_tag="VXF95_002221"
     CDS             1590..1733
                     /locus_tag="VXF95_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HEV1082666.1"
                     /translation="MAESPNSPLSAISDQVGFSDYKYFAKVFKKHLHISPKELKLLGR
                     IVK"
BASE COUNT          605 a          354 c          255 g          551 t
ORIGIN      
        1 tcaaaataaa actatcgttt taagaatccc agttattcct aattttaaca atagtttaga
       61 ggatgcagaa aaattcgcta ctctatttaa ctcattaaat atcgaccaag ttcaactact
      121 cccttttcat caatttggtg aaaacaaata tcgtttatta aatcggaaat atgaaatgga
      181 tggaatcaac gcacttcatc ctgaagatct tattgattat caaaaggtat ttctgaacca
      241 ccatattaat tgttatttct agttcatttc cttgaaatgc tctagctatt tgcagataac
      301 aagcatctat aatacatact taacttttca aaaggtttag ctaaaaaatt ttagccaaac
      361 cttttctatt ttaccttgct ctagaatttt taaactgcta tacttatcac aaaaaaacct
      421 tccaatgagg tagcggatgt ctcattcctt taaaaaatct ctccaaaaag aaattctcca
      481 tagaagctct atcgcagcct ttgtgacctc acgcgcattc tccgatacag tatcaccgat
      541 ttagaaaaag aaacaaccat ttgtcaggat ttaaagatta tagaggatta ccttatgatt
      601 cataagattc gtttcgagca cttttcctat gatattgtct gcccagaaac tgtcgataat
      661 cagcctatcc ctaaactttt cttgcttcct ctagtagaaa atgctataaa acatgggatg
      721 caataccgta ttgatcttca tattgatatc cacattacct tggaagcaga ttctctaact
      781 tttttagtca aggataatgc tggaggactc accaaacaag agcgattcgc tattttagac
      841 tctttagaaa gccctcatac ccagcatggc atcatgaaca gctacaaaca attgagcaat
      901 ttcttttctg atgtccagct agatttagga gtcaatcgcc aaggagaaac ttgggtcaaa
      961 tttgtaacga aagactaact catgtttaag ctcattattg tagaagatga acacctcatc
     1021 cgaaaatggc tagagattgc cgtagactac tctgccttag gcatccaagt cgtaggaact
     1081 gccagtcacg gtcaagaagg aatgaaactc atccaagaaa aagaaactca tatttgtctt
     1141 aacagacatc acaatgccaa ttatggatgc ttttatgatg ttcaaagcca ctcgtactct
     1201 ttcttatgaa aaagttatct tatcaggtta taacgatttt caaaatgcca aaaagccatg
     1261 caatatggag cagttgattt cttatccaag ccaattgata ccaaggaatt gacagaatgt
     1321 cttcaaaaaa ttgttttgcg attacaaatt agcacatctc aagaaactcc ttttttagaa
     1381 gaatatcaaa ctttactcac ctctatccaa caggttgata cacaaaacca aatcattcaa
     1441 caaattatct cctttgtcca caagcactat gcagagcatt actattgctg aagctttaaa
     1501 ctataacgaa agctatctat ataaggttat caaagatgac tctaaatgaa tatatcttac
     1561 aatatcgcct gaaacaagct atagataaga tggctgaatc tcccaactcc cctttaagcg
     1621 ctatctctga ccaagttgga ttttcagact ataaatattt tgccaaagta tttaaaaagc
     1681 atctccatat ttccccaaag gaattgaaat tactcggaag aatagtaaaa taggctattc
     1741 ttctttttgt agagaatttt actct
//
LOCUS       DAVLMQ010000131         1704 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.132, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000131 DAVLMQ010000000
VERSION     DAVLMQ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1704
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.132"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..83
                     /locus_tag="VXF95_002222"
     CDS             <1..83
                     /locus_tag="VXF95_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HEV1082667.1"
                     /translation="MAQQVIPKAAFGYIASGAEDTFTSFQ"
     gene            211..1701
                     /gene="lysS"
                     /locus_tag="VXF95_002223"
     CDS             211..1701
                     /gene="lysS"
                     /locus_tag="VXF95_002223"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HEV1082668.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
BASE COUNT          518 a          373 c          353 g          460 t
ORIGIN      
        1 caatggcgca acaagttatt cctaaagcag catttggcta tatcgctagt ggggcggaag
       61 atactttcac ttctttccag tgattttagc gtcaggttct ttttagtttt taaagattat
      121 ccgtgaattt cttgcttatt tatgataaaa tgggagtatc gcaaaaaatg actcatcgta
      181 ttcaattttg agtaaaacta ggaggatccc atgtctacag aacatatgga agaactaaat
      241 gaccagcaga tcgttcgccg tgaaaaaatg gctgcgctcc gcgaacaagg aatcgatcct
      301 ttcggaaaac gttttgaacg tactgcaaat tcacaagaat taaaagataa atatgccaac
      361 ctcgataaag aacaattaca cgataaaaac gaaacagcta ctatcgcagg acgcttggta
      421 accaaacgtg gtaaaggaaa agttggtttt gcccaccttc aagaccgcga aggccagatt
      481 cagatctacg ttcgtaagga tgctgtcggt gaagaaaact acgaaatctt caaaaaagca
      541 gaccttggtg acttccttgg tgtcgaaggt gaagtgatgc gtacggatat gggagaactc
      601 tctatcaagg caacccacat cacacacttg tctaaggctc ttcgtcctct tcctgagaaa
      661 ttccatggtt tgacagacgt tgaaacaatt taccgtaaac gttaccttga cttgatttct
      721 aatcgtgaaa gctttgaacg ctttgtcact cgttcaaaaa tcatctctga aatccgtcgt
      781 taccttgacc aaaaaggatt ccttgaagtg gaaacacctg ttcttcataa tgaagccggt
      841 ggtgctgctg cccgtccatt tatcacccac cacaatgccc aaaacattga catggtgctt
      901 cgtatcgcga ctgagcttca cttaaaacgc cttatcgtgg gtggtatgga acgtgtctat
      961 gaaattggcc gtatcttccg taacgaagga atggatgcta ctcataaccc tgagttcact
     1021 tctatcgaag tttaccaagc ttatgcagac ttccaagata tcatggactt gacggaaggc
     1081 attatccaac atgctgctaa atcagttaag ggcgatggcc cagtcaacta ccaaggtact
     1141 gaaatcaaga ttaacgaacc atttaagcgt gttcatatgg tggatgctat cagagaaatt
     1201 actggtgtcg atttctggca agacatgact ttgaaagaag ctaaagctat cgctgctgag
     1261 aagaaagttc cagttgagaa acactacact gaggttggtc acatcatcaa tgccttcttt
     1321 gaagagtttg ttgaagaaac tttaatccaa ccaacctttg tctatggaca tccagtagct
     1381 gtatctccac tcgctaagaa aaatcctgaa gaccaacgct ttactgaccg tttcgagctc
     1441 tttatcatga ctaaggagta cggtaatgcc tttactgagc tcaacgaccc aatcgaccaa
     1501 cttagccgtt ttgaagccca agctaaagct aaagaacttg gtgatgatga agcgacaggc
     1561 atcgactatg actacatcga ggctcttgaa tacggtatgc caccaacagg tggtttggga
     1621 atcggtatcg accgtctctg catgctcctc actgatacaa caactatccg tgatgtattg
     1681 ctcttcccaa caatgaaata aatt
//
LOCUS       DAVLMQ010000132         1634 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.133, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000132 DAVLMQ010000000
VERSION     DAVLMQ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1634
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.133"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            61..132
                     /locus_tag="VXF95_002224"
     tRNA            61..132
                     /locus_tag="VXF95_002224"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:93..95,aa:Gln,seq:ttg)
     gene            294..1496
                     /gene="rpsA"
                     /locus_tag="VXF95_002225"
     CDS             294..1496
                     /gene="rpsA"
                     /locus_tag="VXF95_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HEV1082669.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
BASE COUNT          493 a          274 c          381 g          486 t
ORIGIN      
        1 gactgtaaat ccgctccttc gggttcgggg gttcgaatcc ctctctctcc atttcattaa
       61 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      121 cagctacccc agttcttagg taataatcaa gatagaaagc aaaatatctt agggtatttt
      181 atttttataa ttgaaagacg tgaatgatat gaacatgtcc ttgcgggtgc ttaggaaaaa
      241 aattataagt atgtcaagtt taagaaaaac ttgattgttg gaggattttt tagatgaacg
      301 aatttgaaga tttgctaaat agcgttagtc aagttgagac tggtgatgtt gttagtgctg
      361 aagtattgac agttgatgcg actcaagcta acgttgcaat ctctggaact ggtgttgaag
      421 gtgtcttgac tcttcgcgaa ttgacaaacg atcgtgatgc agatatcaat gactttgtta
      481 aagtaggaga agtattggat gttcttgtac ttcgtcaagt agttggtaaa gatactgata
      541 cagttacata ccttgtatct aaaaaacgcc ttgaagctcg caaagcatgg gacaaacttg
      601 ttggtcgcga agaagaagtt gttactgtta aaggaacgcg tgccgttaaa ggtggacttt
      661 cagtagaatt tgaaggtgtt cgtggattta tcccagcttc aatgttggat actcgtttcg
      721 tacgtaacgc tgagcgtttt gtaggtcaag aatttgatac taaaatcaaa gaagttaacg
      781 ctaaagaaaa ccgcttcatc ctttcacgtc gtgaagttgt tgaagcagct actgcagcag
      841 ctcgcgctga agtattcggt aaattggctg ttggtgatgt tgtaactggt aaagttgctc
      901 gtatcacaag cttcggcgct ttcatcgacc ttggtggtgt tgacggattg gttcacttga
      961 ctgaattgtc acatgaacgt aacgtatcac caaaatcagt tgtaactgtt ggtgaagaaa
     1021 ttgaagtgaa aatccttgat cttaacgaag aagaaggacg tgtatcactt tcacttaaag
     1081 caacagtacc aggaccatgg gatggcgttg agcaaaaatt ggctaaaggt gatgtagtag
     1141 aaggaacagt taaacgtttg actgacttcg gtgcatttgt tgaagtattg ccaggtatcg
     1201 atggacttgt tcacgtatca caaatttcac acaaacggat tgaaaatcca aaagaagctc
     1261 ttaaagttgg tcaagaagtt caagttaaag ttcttgaagt taacgcagat gcagaacgcg
     1321 tgtcactttc tattaaagct cttgaagaac gtccagccca agaagaagga caaaaagaag
     1381 aaaaacgtgc tgctcgtcca cgtcgtccaa gacgtcaaga aaagcgtgat ttcgaacttc
     1441 cagaaacaca aacaggattt tcaatggctg atttgtttgg tgatatcgaa ctttaatcaa
     1501 attgaaaatt cacaaaatcc tttgtttact aaacaaggga tttttctggc tctttgtcaa
     1561 ctgtagtggg ttgaagtcag ctaagcttga gaaaggacaa atttcgtcct ttcttttttg
     1621 atgttcaaag cgat
//
LOCUS       DAVLMQ010000133         1629 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.134, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000133 DAVLMQ010000000
VERSION     DAVLMQ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1629)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1629)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1629
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.134"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..331
                     /locus_tag="VXF95_002226"
     CDS             <1..331
                     /locus_tag="VXF95_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082670.1"
                     /translation="EIIYFYSQVKVVDKLTDSESKKYGEYIDLYESCRQNNLSVLLNF
                     LQNSDDKRGVIASNSVRIMFESLDKADQIAALNICRNYVARENVLNKEDAEKLLNEID
                     KKLEISR"
     gene            387..1082
                     /locus_tag="VXF95_002227"
     CDS             387..1082
                     /locus_tag="VXF95_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082671.1"
                     /translation="MPVNEYGQMIGESMEGYTPGALPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPREMWTYLFQEPVADMGELVSLLNQMLARKDRFYYAIIDKATGKALG
                     TFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYIFEELNYRRYEWKCDAL
                     NLPSRRVAERLGFVYEGTFRQAVVYKGRTRDTDWLSMIDMDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            1094..1510
                     /locus_tag="VXF95_002228"
     CDS             1094..1510
                     /locus_tag="VXF95_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082672.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEHALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVFVQDLIVLPIYQRQGIGSALMKEALKDYKDAYQVQ
                     LVTEETEKNVGFYRSMGFEILSTYNCIGMTWANREK"
BASE COUNT          509 a          253 c          381 g          486 t
ORIGIN      
        1 ggaaataatc tatttttatt cgcaggtaaa agttgtagat aaacttactg attctgaatc
       61 gaaaaaatac ggtgaatata ttgatttgta cgaatcgtgt cgtcagaaca atttaagtgt
      121 tctacttaac tttcttcaaa attcggatga taaacgagga gttattgcta gtaactcagt
      181 gagaattatg tttgaatctt tggataaagc agaccaaatt gcggccctga atatttgtag
      241 aaactatgta gcacgagaaa atgttttaaa taaagaagat gcagaaaaat tgttaaatga
      301 aattgataaa aaacttgaaa ttagcagata ggacaattca aatagagttg agtaaaaagt
      361 ttgaaaagtg aaacaaggag aaagctatgc cagtaaatga atatggtcag atgattggtg
      421 agtcaatgga aggttataca cccggtgcac tgccttctat tgatttctta gaagggcgtt
      481 atgctaggat agaggctctc tcggtagaaa aacatgcgga ggatttgcta gctgtttatg
      541 gcccggatac tcctcgggag atgtggacct atctttttca ggagccagta gcagatatgg
      601 gggagctggt tagcctttta aatcagatgt tggctcgtaa ggaccgtttt tactatgcaa
      661 tcatagacaa ggcgactggt aaggctttgg gaactttttc tctcatgcgc attgaccaga
      721 ataaccgagt aatagaagtc ggagcagtca ctttttctcc agagctaagg ggtacacgga
      781 taggaactga ggctcagtat ctcctagctc gctatatttt tgaggagcta aactatcgtc
      841 gctacgagtg gaaatgcgat gccttaaatc tgccatccag acgagttgcg gagcgtttgg
      901 gatttgtcta tgaaggaacc ttccgccagg cggtggttta taaggggcgt acgagagata
      961 cggattggtt gtctatgatt gatatggact ggcctcaagt caaagatcgt ttggaaacat
     1021 ggctgcgtcc tgaaaatttt gataaaaatg gacagcagta caagagcttg agagaacttt
     1081 aagaggtgtt gagatgatta ctattaaaaa gcaagaaatt gtcaagctag aggatgtttt
     1141 gcatctctat caggctgtcg gttggacaaa ttatacccat caaccagaga tgctggagca
     1201 tgccttatcg cattcattag taatttatct ggcacttgat ggtgatgctg tggtgggctt
     1261 gattcgtttg gttggagatg gattctcatc agtttttgta caggatttga ttgttttacc
     1321 aatctatcag cgtcaaggga ttggtagtgc cctaatgaaa gaggccttaa aagattacaa
     1381 agatgcttat caagtccagc tggtgacaga agagacagaa aaaaacgtgg gattttatcg
     1441 ttctatgggc tttgaaatct tatccaccta taattgtata gggatgactt gggcgaatcg
     1501 agaaaaataa caaaacttgt tttttcttaa gcaaaattta aggatggtct agtattatat
     1561 agtcattaaa taaagacctc ctaactttat ttaataaaat cctaaacttt tttcatcaca
     1621 atctcctaa
//
LOCUS       DAVLMQ010000134         1623 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.135, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000134 DAVLMQ010000000
VERSION     DAVLMQ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1623)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1623)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1623
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.135"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..772)
                     /locus_tag="VXF95_002229"
     CDS             complement(<1..772)
                     /locus_tag="VXF95_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082673.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIDSKGIFVSILMAVLLLYLI
                     YFIATVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREISLLLATIIVYFFTHRILPFSVFTFMFSYILLFVQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNFTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNY"
BASE COUNT          620 a          283 c          199 g          521 t
ORIGIN      
        1 agtaattgaa tcccatagta tatttttctt tataaagcaa aggtaaaact ttataaaaaa
       61 tatctaagtc aacctcactc tgattctgaa gcaagtagga gtcaagcaaa ttttcaaaaa
      121 tagctaacaa tatgattggt gtaaagtttt tgtattcaca tgtcaagtat tctgagtatc
      181 gtgcagatga tatttctttt atataacttt ttgaaagcaa gattttttca aattcatcat
      241 ctattattaa tcttctattt ccaatccaag cggtattacc acccaaataa gattgtacaa
      301 atagcaatat ataagaaaac atgaacgtaa atactgaaaa aggtagaatt ctatgcgtaa
      361 aaaaatagac gataatggta gccaggagta aagatatctc tcgtgacaat cgaattcttt
      421 tcagcatctt ttttaacagt ccgtaaggtt gtccttggca atattcttga actaaattaa
      481 tcggaatgac atctctcacc atttctggaa agtagagtaa gtttataggt tgaaatctcc
      541 agctcccatc ataagtaaat ggatatagaa ccaaatactt aaaagatttt tttcttataa
      601 acttaattat cacaatatga atgactgttg caatgaagta tattaaatat aaaagtaaaa
      661 ccgccatcaa tatacttaca aaaatcccct tggaatcaat caatggaaaa taaaatattg
      721 caactagaag cgaataaagt cccgctaata aatatttctg atcatctttc attcaaaaca
      781 ccatattatt tactaagaat gcatcaatac aatagagcaa ctctgtaagt caatatttga
      841 taaagcaaag ctttaacccc ttccccagac gttagctttt cttcaaccca ctacagttga
      901 caaggagccc aaattattga taaaaacttt agtcatcatc gtctctataa aatattttct
      961 atacactctt gataatacca aaattaatgc caatatcata ccaagagcta taataataga
     1021 atttattaga tttattttag tatatccaat cactagtcca ataattggac tagcagacat
     1081 gcttagatat aataaaaata acaaaaaatg aatttcacca attcctgcaa aaaaatgttt
     1141 catagctata gttttacgcc cataaatacc catcaaattt accgtctacg atatctaaac
     1201 catatgcaat ggctcctcct aatgagaaga cttcagcaac agtagccgca atattaagag
     1261 cattagtaat agttgccata ctaactccac caatatatct tgttataaca cttagttacc
     1321 tagataagat atcctttagc ttgcttccaa aatttaagtc tgcacctata atatgagttc
     1381 atattaatac tgctaaatcc tatctatagt aatgtcaaac acccaaataa agtcatctct
     1441 ccaattcatt caagaaatga agaaaggcaa aaaatcttta aaataagaaa aatgcatatt
     1501 atcaggtgtt caaaaatatt gatgatatac gttatataga tagaaagatt tactcaatct
     1561 cattttcaaa ttgagttttt tcccagcctc gtttttaatt tatatcttca atagaatcta
     1621 atg
//
LOCUS       DAVLMQ010000135         1602 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.136, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000135 DAVLMQ010000000
VERSION     DAVLMQ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.136"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(137..1561)
                     /locus_tag="VXF95_002230"
     CDS             complement(137..1561)
                     /locus_tag="VXF95_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HEV1082674.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAVERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEATSKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVAEKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
BASE COUNT          466 a          357 c          284 g          495 t
ORIGIN      
        1 caatgtttta gaagtagagc tgtactattc tagtttcaat atactataat accaaaaagt
       61 tcgtattttt tctataatta ttattatttt atagcaaaaa aataaaacca ggaaaacaat
      121 ttcctgattt tacacgttat ttcacatcaa aaacaatgga tttgacattt gtcatcgctt
      181 caatgctata tttaattcct tgcactccag ctccagaacc tttgacacca aggaatggga
      241 aattatctgg accacgctgg gttttattat taatgtggac tgtacctact tcaagttttt
      301 cagcaatttc aaaggctttt ttgaaatcat ttgtaaagac tgatgattga aggccgaatt
      361 cagattcgtt ggcaaaggca atagcttcct ctacactagc cacacgaatg attggtaaaa
      421 caggaccaaa tggctcttcc catgccactt tcatatcttt tgtaacttgg tcaaaaagca
      481 ctggccagag gagattgccc tcacgtttga ttggtgtaag agcctgagcc tctttttctt
      541 gtgcatcctc aatcaagccc caaatgaagt cggctgaagc attgtcaata acaggtgtaa
      601 tatcagcatt gtcaaatgga tcaccaactg ttaatttaga aacttcttcc tgaagcaaag
      661 tagctaattt ctctgctaca ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt
      721 gtcctgagta gctaaaggct cccgcaacaa tttgcttggc agcatgttcc aaatctgcat
      781 cttctagtac aagagctgca tctttcccac caagttccaa catgatagga cgcataccag
      841 ctaaacgacc aatacgttct ccaataggag ttgaacctgt aaagttgatg aagttgactt
      901 ctttgtgctc aatgatataa tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa
      961 cacctgccgg aatccctgct tcttcaaatg ctttagccaa caagagtcca gaaatggaac
     1021 cttgtgttgg tggcttaaac atgaccacat tccctgcaat caaggcaggt gcaattttag
     1081 aagcagataa attaactgga taattaaagg gagcaatcgc tagcacgata ccaactggtt
     1141 cacgacggac aacagccagt ttgtttttac ttgttgcctc aaaaccacca ccttccattg
     1201 cttgtccagt gatacggaga ccttcctcag cagcataacg aatcaagtct gctgtacgca
     1261 ctacttctcc aattgctgct ttaatccctt ttgctacttc tttggcaagg atagtaccaa
     1321 tttcttcctt atcgcgttct aaaatagctg ctgttttatg caaataagcc gcacgttcaa
     1381 ctgctgataa agctcgccat gctggcaggg ctgcacgcgc agcttgcata gcctcatcag
     1441 cttcagtctg agtcatggct ggaactgtac ccaattcttc ttgattgatt ggtgaataaa
     1501 tcgtaatttc ttgttcagat gatttccatt ttccatttac taaattctga tatcttgtca
     1561 aattcttgtc ctcctgaaaa tgattaagat atattttacc aa
//
LOCUS       DAVLMQ010000136         1539 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.137, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000136 DAVLMQ010000000
VERSION     DAVLMQ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.137"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>1539
                     /locus_tag="VXF95_002231"
     CDS             <1..>1539
                     /locus_tag="VXF95_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HEV1082675.1"
                     /translation="YVTSHGDHYHYYNGKVPYDAIISEELLMKDPNYQLKDSDIVNEI
                     KGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEHSHNHGGGSNDQAVVAARAQG
                     RYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSDLSASELAAAQAYWNGKQGSR
                     PSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISSLLRELYAKPLSERHVESDGL
                     IFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRIARIIPLRYRSNHWVPDSRPE
                     QPSPQSTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYVFEENGVSRYIPAK
                     DLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDLLARIHQDLLDNKG
                     RQVDFEALDNLLERLKDVSSDKVKLVDDILAFLAPIRHPERLGKPNSQITYTDDEIQV
                     AKLAGKYTTEDGYIFDPRDITSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKE
                     KGLTP"
BASE COUNT          489 a          332 c          320 g          398 t
ORIGIN      
        1 tatgtgacct ctcatggaga ccattatcat tactataatg gcaaggttcc ttatgatgcc
       61 atcatcagtg aagagctcct catgaaagat ccgaattatc agttgaagga ttcagacatt
      121 gtcaatgaaa tcaagggtgg ttatgtcatt aaggtaaacg gtaaatacta tgtttacctt
      181 aaggatgcag ctcatgcgga taatattcgg acaaaagaag agattaaacg tcagaagcag
      241 gaacacagtc ataatcacgg gggtggttct aacgatcaag cagtagttgc agccagagcc
      301 caaggacgct atacaacgga tgatggttat atcttcaatg catctgatat catcgaagat
      361 acgggcgatg cctatatcgt tcctcatggc aatcacttcc actatattcc taagagtgat
      421 ttatctgcca gtgaattagc tgctgcccaa gcctattgga atgggaagca gggatctcgt
      481 ccttcttcaa gttctagtca taatgcaaat ccagctcaac caagattgtc agagaaccac
      541 aatctgactg tcactccaac ttatcatcaa aatcaagggg aaaacatttc aagcctttta
      601 cgtgaattgt atgctaaacc cttatcagaa cgccatgtag aatctgatgg ccttattttc
      661 gacccagcgc aaatcacaag tcgaaccgcc agaggtgtag ctgtccctca tggtaaccat
      721 taccacttta tcccctatga acaaatgtct gaattggaaa aacgaattgc tcgtattatt
      781 ccccttcgtt atcgttcaaa ccattgggta ccagattcaa gaccagaaca accaagtcca
      841 caatcgactc cggaacctag tccaagtccg caacctgcac caaatcctca accagctcca
      901 agcaatccaa ttgatgagaa attggtcaaa gaagctgttc gaaaagtagg cgatggttat
      961 gtctttgagg agaatggagt ttctcgttat atcccagcca aggatctttc agcagaaaca
     1021 gcagcaggca ttgatagcaa actggccaag caggaaagtt tatctcataa gctaggagct
     1081 aagaaaactg acctcccatc tagtgatcga gaattttaca ataaggctta tgacttacta
     1141 gcaagaattc accaagattt acttgataat aaaggtcgac aagttgattt tgaggctttg
     1201 gataacctgt tggaacgact caaggatgtc tcaagtgata aagtcaagtt agtggatgat
     1261 attcttgcct tcttagctcc gattcgtcat ccagaacgtt taggaaaacc aaattcgcaa
     1321 attacctaca ctgatgatga gattcaagta gccaagttgg caggcaagta cacaacagaa
     1381 gacggttata tctttgatcc tcgtgatata accagtgatg agggggatgc ctatgtaact
     1441 ccacatatga cccatagcca ctggattaaa aaagatagtt tgtctgaagc tgagagagcg
     1501 gcagcccagg cttatgctaa agagaaaggt ttgacccct
//
LOCUS       DAVLMQ010000137         1507 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.138, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000137 DAVLMQ010000000
VERSION     DAVLMQ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1507
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.138"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(52..1335)
                     /locus_tag="VXF95_002232"
     CDS             complement(52..1335)
                     /locus_tag="VXF95_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HEV1082676.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
BASE COUNT          501 a          304 c          325 g          377 t
ORIGIN      
        1 tatacgaaaa atccactcag ctgtctgagt ggattaggtg tatttagact cttagtcttt
       61 attttcgtat ggcaagatca agttcaagat gattcctgtc atggctgaaa gggcagtacc
      121 tgaaagtgta actggaccaa gtttaaggat agctcctcca agtccaagaa ccaacatagc
      181 acttgcgatg atgaggtttc gcatttgagc gaaatcaaca cgttctttaa tcaagacttt
      241 caaaccattg ctggcgataa ccccatagag aaggattgac ataccaccaa gtacagcgtt
      301 tggaatagtt gaaatcaagg cagtgaattt accaaggaag ctgagggcaa tcgcgatgaa
      361 ggcagcgtta cggataactg agacagaagc gatacgagtc ataccgataa cccctgtatt
      421 ttctccgtaa gttgtattgg ctggtccacc aaggaaggca gaaacagaag ttgcgatacc
      481 gtcaccaaga agagtacggt gaagacctgg ttcttttaag aattgacgac cacagatttg
      541 acccaaaaca gtatggtctc cgatatgttc agaaattgtt acgatagcga ttggcaagat
      601 agcgatggct tctggaccaa agtaaagatt gtactcttta aaggcaccac ctgtgctaaa
      661 tggcaagtag aaaccaggaa tttcgaacca gttggcttta agaactggtg taaagtcaac
      721 caagccaaga gttagtgcga aaaggtaacc accgataatg gcaaagagga atggaatgat
      781 tcgtaggaag ccttttcctt ttgtattgat aaaggcagca attaggaaag taacaacggc
      841 taccagagca tttttccaat ttccgtctgc tacaagacct gcattggtaa cagctgaacc
      901 tgcaagtcca agaccgataa cgatgatcat aggaccgata atgattggtg gcaagagttt
      961 atcaatccat tttgttccta caaatcggat gctggtagca acaaggacat agaccaaacc
     1021 agtcaagata acccctgttt gggcagcaga tacatccccc cccatttctt tcatagccag
     1081 tgacatagct gtgataaagg caaatgaaga acctagataa actggaactt taaaaccagt
     1141 agcaatcatg tagatgagtg ttccaacacc tgaagcaaaa agggcaacag atacaggcat
     1201 tcccaaaatc aatggtacca agatggtcgc accaaacatg gcgaaaacgt gttggaaact
     1261 aaggagaatt ccttttccat ccgaaggacg ttggtcaacg tctagtaaca aatcaacagt
     1321 tgattcttgt ttcatataaa cctcactttt gggcatcaaa aaagagccca ttattttaca
     1381 gcaataggcc ctcagagtaa gacttcttta aaatttagat tttaaagagt tttaaatatt
     1441 tctgcgtctt cgtcacctca cgggatgaca ttaaaaacct ttgcttagga tagtatagca
     1501 gaaaaaa
//
LOCUS       DAVLMQ010000138         1477 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.139, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000138 DAVLMQ010000000
VERSION     DAVLMQ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1477
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.139"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..415
                     /locus_tag="VXF95_002233"
     CDS             <1..415
                     /locus_tag="VXF95_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="diadenosine tetraphosphate hydrolase"
                     /protein_id="HEV1082677.1"
                     /translation="DTSFVEMSYSQFFEGYCILFSKEPYPSLSDMPMEFRKEFLMEMS
                     ILGDAMLEVLNAYRINYDILGNSTPVLHAHLFPRYMWEEEERRKTVVHRYDSSVFSNP
                     EFEFTIEKHGPIIKKLRSAIDRHYREYQQLLDDSN"
     gene            920..1369
                     /locus_tag="VXF95_002234"
     CDS             920..1369
                     /locus_tag="VXF95_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HEV1082678.1"
                     /translation="MELVEFKNGHVNTVHEHIAITKVKEFLNNHDISKDKGGIHKIST
                     DFFYNIIDMETTTEENRPWESHKEYYDVHYLLNGEETILYNFLSQMELSEYKVDDDWQ
                     QMNGEALFSIILKKNMLLLLEPNDAHKTGLLVEEPINIKKVVFKVKI"
BASE COUNT          542 a          159 c          258 g          518 t
ORIGIN      
        1 tgatactagc tttgtagaaa tgtcttattc tcagtttttt gaaggatatt gtattctttt
       61 ttcaaaagaa ccctatcctt ctttatctga tatgccaatg gaatttagaa aagaattttt
      121 aatggaaatg agtatattag gtgatgcgat gcttgaagtg ttaaatgcct atagaattaa
      181 ttatgatatc ttaggaaatt caacacctgt acttcatgct catttatttc cgagatacat
      241 gtgggaagag gaagagagaa gaaaaactgt agttcataga tatgattctt cagtttttag
      301 caatcctgag tttgaattta ctatagaaaa gcatggacca attattaaaa aactgaggtc
      361 tgctattgat agacattata gagagtatca acaattatta gatgattcaa actgaactcc
      421 acattttcga ttagatttaa taccttgtat attacaacta ggttgtggat gatataattt
      481 tttgaaaaat atattttagg aatgacttat aaagcaatta tatcagaggc tattaaatca
      541 atggccaaag cttatgctcc ttattcttat tttaaggttg gagctgcgtt agaaactgaa
      601 gataaaaatt ttttcctgga tgtaatatag aaaatgttgc ttttctccta cttgctgtgc
      661 agaacgagta tatttttaca aagctgtatt taaaggagaa cgttcgtttt caaaaatatg
      721 tattgtaggc ggaaaaaaag gtattttatc atcttttata gcatcttgca gggtgtcttg
      781 tcaggtaatg atagaatttt gtaatcttga ttcatttgta gttatattgg ctagtgatgt
      841 tgataattat aaagtatata aacttaaaga actactacca gttagtttta atcaagaaaa
      901 tttataacag gagggaacta tggaattagt tgaatttaaa aatggacatg ttaatacggt
      961 tcatgagcat atcgcaataa cgaaagtaaa agagtttcta aataatcatg atatatcaaa
     1021 agataaaggt ggcatacata aaatttctac tgatttcttt tacaatataa ttgatatgga
     1081 aactacaact gaagagaata gaccgtggga aagtcataag gaatattatg atgtccatta
     1141 tctgttaaat ggagaagaaa caattttata taatttcttg tctcaaatgg aattgtctga
     1201 atataaagta gatgatgatt ggcaacaaat gaatggggaa gctttattta gtattatatt
     1261 aaagaaaaat atgttacttt tgttggaacc aaacgatgca cataaaacag gcctattggt
     1321 tgaagaacca attaatatta agaaagttgt ttttaaggta aaaatttaac tgaaagtact
     1381 ttcagggatt aagaatttta aaatatttaa gaaattgtat tctaaagttc taaaattata
     1441 gatatttaat ttaaagcttg ttaaaataga atagtaa
//
LOCUS       DAVLMQ010000139         1464 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.140, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000139 DAVLMQ010000000
VERSION     DAVLMQ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1464)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1464)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1464
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.140"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            17..1012
                     /locus_tag="VXF95_002235"
     CDS             17..1012
                     /locus_tag="VXF95_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082679.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKRFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGEKANMDVVLVFSKLSDSEKKQLLQARVPFVDFKG
                     NLFFPPLGLVLNANDTEVPKELTPSEQLTWIAFLLTKGQKVVDVDLLSQVTGLPNSTI
                     YRCLRTFKALYWLNKQNKLYTYTVSKKELFLKSVSCLFNPIKKRILLPDGDIKQIKSV
                     SNLLYGGAYALSHSTFLAETDENISYVIWQRKFNQLSLPLSQHVLKGKMLEIWKYRPF
                     VSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRIEEESEALENMILQYLGEDDAS"
     gene            1002..>1464
                     /locus_tag="VXF95_002236"
     CDS             1002..>1464
                     /locus_tag="VXF95_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082680.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFQFTTTNPEFPSMIELFSIL
                     PEYPLKKDGREIPLYFDQDASLSALLLDEDYYNILVHVKETIQGYSVLSNCG"
BASE COUNT          494 a          205 c          282 g          483 t
ORIGIN      
        1 agaataagga aaaaacatga atgtcaaaaa gataatgtca atttttcaat ccttttatgt
       61 tgatgtcagt attgaggaac tgactttgac tttaccaatc agttttgtaa aaaggtttga
      121 gtatactcaa atgacttttc ataaggaatc atttttattg attaaagaaa agagaagggg
      181 gagtttgagt tcatttgtta ctcaggctcg cactatgggt gaaaaagcca atatggatgt
      241 tgttttggtg ttttcgaagt tatcagacag tgaaaaaaag caattacttc aagctagagt
      301 tccgtttgta gactttaagg gaaacctctt cttccctcca ttgggactag tactgaatgc
      361 gaatgatact gaagtcccta aggaattaac acctagcgaa caattaacgt ggattgcctt
      421 tttattgaca aaaggtcaaa aagtagtaga tgttgatttg ctttcacaag tcactggact
      481 tccaaactca acaatttata ggtgtttgag gacttttaaa gctttatatt ggttaaacaa
      541 gcaaaataag ctttacacat atacggtgtc aaagaaagaa ttattcttaa aatccgtgtc
      601 atgtttattt aatcccatca aaaaacggat tttattgcca gatggcgata taaagcagat
      661 aaaatctgtt tctaatcttc tatatggtgg tgcttatgct ttgtcgcatt caactttttt
      721 agctgaaacg gatgaaaata ttagctatgt catatggcag agaaaattca atcagttatc
      781 cttgccactt tctcagcatg ttttaaaagg aaagatgcta gagatatgga aatatcgtcc
      841 ttttgtatct gagttttgga atgattttaa aaataatcat gataaacaat ttgtagatcc
      901 gatttctctt tatttgacct taaaagatga tgatgaccca cgtatagagg aagagagtga
      961 agcactagaa aatatgatat tacagtatct gggagaagat gatgccagct aatacgaaag
     1021 ttatttttca agaaatgttt gcggattttc agaactatta tgttctgatt gggggaactg
     1081 ctacctctat cgtattggat tcgcaaggat ttaaaagtcg cacaacaaaa gattatgata
     1141 tggtcatcat tgatgaagta aaaaataagg aattttatac taccttgaat cattttttag
     1201 aattgggaga gtatcaagga agtcagaaag atgagaaagc gcagcttttt caatttacaa
     1261 caactaatcc tgagtttcct tctatgattg aactatttag tatcttacca gaatatccat
     1321 taaagaagga cggtcgagaa attcccttat attttgatca agatgctagt ttatcagcct
     1381 tattattgga tgaagattat tataatatat tggtgcatgt aaaagaaacc attcaggggt
     1441 attcggtatt gagtaattgt ggtc
//
LOCUS       DAVLMQ010000140         1454 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.141, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000140 DAVLMQ010000000
VERSION     DAVLMQ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1454
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.141"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            484..>1454
                     /locus_tag="VXF95_002237"
     CDS             484..>1454
                     /locus_tag="VXF95_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HEV1082681.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESSEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRK"
BASE COUNT          432 a          246 c          316 g          460 t
ORIGIN      
        1 ttaataaatt ctttgagctt ttttcttttt aaatattgat tgtttctaaa agttctagta
       61 atattgctat ttctcatttt tccaaatatg ttattcaact tattagctac gtctctattc
      121 atatttgggt ataaaacaaa aaatcaattc taacagtttt atatcataat aataaataaa
      181 aaagcgatat tctagactgt atcaatcctt ttccattata ggagcaacag agtgggagta
      241 gtcatctaag gactaattta tatattttta cgagtcagta tcttgggata ctggttttta
      301 cttttttaga ctttttgact acttgttaaa actggggtaa ttttcgactg tttaatagtt
      361 attatgcaaa gtctaaaaga ttagaattgt caaaacaatc cgtctaggct tgattttatc
      421 ctttatttac tataaaatga gaaggaaaaa tgtcaaactt ttatattgca aataggagaa
      481 attatgacaa aaacattaaa acgtcctgag gttttatcac ctgcagggac tttagagaag
      541 ctaaaggtag ctgttcagta tggagcagat gctgtcttta tcggtggtca ggcctatggt
      601 cttcgtagcc gtgcgggaaa ctttactttc gaacagatgg aagaaggcgt gcagtttgcg
      661 gccaagtatg gtgccaaggt ctatgtagcg gctaatatgg ttatgcacga aggaaatgaa
      721 gctggtgctg gtgagtggtt ccgtaaactg cgtgatatcg ggattgcagc agttatcgta
      781 tctgacccag ccttgattat gattgcagcg actgaagcac caggccttga aatccacctt
      841 tctacccaag ccagtgccac taactatgaa acccttgagt tctggaaaga gctaggcttg
      901 actcgtgtcg ttttagcgcg tgaggtttca atggaagaat tagctgagat ccgcaaacgt
      961 acagatgttg aaattgaagc ctttgtccat ggagctatgt gtatttcata ctctggacgt
     1021 tgtactcttt caaaccacat gagtatgcgt gatgccaacc gtggtggatg ttctcagtca
     1081 tgccgttgga aatacgacct ttacgatatg ccatttggga aagaacgtaa gagtttgcag
     1141 ggtgagattc cagaagaatt ttcaatgtca gccgttgaca tgtctatgat tgaccacatt
     1201 ccagatatga ttgaaaatgg tgtggacagt ctaaaaatcg aaggacgtat gaagtctatt
     1261 cactacgtat caacagtaac caactgctac aaggcggctg tggatgccta tcttgaaagt
     1321 tctgaaaagt ttgaagctat caaacaagac ttagtggacg agatgtggaa ggttgcccaa
     1381 cgtgaattgg caacaggttt ctactacggt ataccatctg aaaatgagca gttgtttggt
     1441 gctcgccgta aaat
//
LOCUS       DAVLMQ010000141         1416 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.142, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000141 DAVLMQ010000000
VERSION     DAVLMQ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1416
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.142"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            27..1373
                     /gene="gdhA"
                     /locus_tag="VXF95_002238"
     CDS             27..1373
                     /gene="gdhA"
                     /locus_tag="VXF95_002238"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HEV1082682.1"
                     /translation="MTSAKEYIQSVFETVKTRNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGVICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
BASE COUNT          422 a          285 c          307 g          402 t
ORIGIN      
        1 aaatatgaca ataaaaggag aacgatatga catctgctaa agaatatatc caaagcgtgt
       61 tcgaaactgt aaaaactcgt aacgggcacg aggctgaatt cctccaagct gttgaagaat
      121 ttttcaacac tttggaacct gtatttgaaa aacaccctga gtatatcgaa gaaaatatct
      181 tggcacgtat tactgagcct gagcgcgtgg tttctttccg tgttccttgg gttgaccgtg
      241 atggaaaaat tcaagtaaac cgtggttacc gtgttcaatt caactcagct gttggaccat
      301 acaaaggtgg acttcgtttc cacccaactg taaaccaagg gatcttgaaa ttcctcggat
      361 ttgaacaaat ctttaaaaat gtcttaactg gacttcctat cggtggaggt aaaggtggat
      421 cagacttcga tcctaaaggt aaaacagatg ctgaagtgat gcgcttctgc caaagcttca
      481 tgactgaatt gcaaaaacac atcggaccat cacttgacgt acctgctggt gatatcggtg
      541 ttggtggacg tgagattggt tacctttacg gtcaatacaa acgtcttaac caatttgatg
      601 ctggtgtctt gactggtaaa cctcttggat ttggtggtag cttgattcgt ccagaagcaa
      661 ctggttacgg tttggtttac tatactgaag aaatgctcaa agctaacggt aacagctttg
      721 ctggtaagaa agtcgttatt tcaggttctg gtaacgttgc tcaatatgct cttcaaaaag
      781 caactgaact cggtgcaact gttatttctg tttctgactc aaatggttat gtcatcgatg
      841 aaaatggtat cgacttcgat cttttggttg atgttaaaga aaaacgtcgt gctcgtttga
      901 ctgagtatgc agctgaaaaa gcaactgcaa cctaccacga aggtactgta tggacttacg
      961 ctggaaacta tgacattgct cttccatgtg ccactcaaaa cgaaatcaac ggtgaagcag
     1021 ctaaacgttt ggttgctcaa ggcgttatct gtgtatctga aggtgccaac atgccgagcg
     1081 accttgatgc catcaaagtt tacaaagaaa atggtatctt atacggacct gcaaaagctg
     1141 ccaacgctgg tggtgtagcc gtttcagctc ttgaaatgag ccaaaacagt cttcgcctct
     1201 catggactcg tgaagaagtt gatgaccgtc tcaaagacat catgacaaac atcttcaaca
     1261 cagctaaaac aacttcagaa acatacggtc ttgataaaga ctaccttgca ggagctaaca
     1321 ttgctgcctt tgaaaatgta gcaaatgcca tgattgcaca aggtattgtt taagatttat
     1381 ttactcaatc ctcaatcact acgattgggg attttt
//
LOCUS       DAVLMQ010000142         1363 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.143, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000142 DAVLMQ010000000
VERSION     DAVLMQ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1363)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1363)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1363
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.143"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            30..869
                     /locus_tag="VXF95_002239"
     CDS             30..869
                     /locus_tag="VXF95_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HEV1082683.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            976..1251
                     /locus_tag="VXF95_002240"
     CDS             976..1251
                     /locus_tag="VXF95_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HEV1082684.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
BASE COUNT          452 a          210 c          293 g          408 t
ORIGIN      
        1 ctgaatccta aaatagaaag attgatacta tgacaaaaat taagattgta accgattcat
       61 ctgttactat tgaacctgaa ctagtaaagc aattagatat tacaattgtt ccattatctg
      121 taatgattga taatgttgtt tattctgatg cggatttgaa agaagaaggt aaatttcttc
      181 agttgatgca agaaagtaag aatcttccga aaacaagtca gccacctgta ggtgtctttg
      241 ctgagatttt tgaagaccta tgcaaagatg gtggccagat tcttgctatt catatgtccc
      301 atgctctttc gggtacggta gaagcagcac gccaaggtgc tagcctatct actgcagatg
      361 tgactgttgt tgatagttcc ttcactgacc aagccctgaa attccaagtt gttgaggctg
      421 cgaagttagc tcaagaaggt aaagatatgg aggcaatttt atgtcatgta gaagaggtta
      481 aaaaccatac agagctttat attggtgttt caactttgga aaatcttgtc aaaggtggac
      541 gaattagccg tgtaactggc ttgttgagct ctcttctcaa tatccgtgtt gtcatgcaaa
      601 tgaaagacca tgaattgcag ccaatggtta aaggtcgtgg aactaaaaca tttaaaaaat
      661 ggttagatga gttgataaca tcgctttctg aacgtgctgt agcagagatt ggaatttcat
      721 attctggtag tgatgattgg gcaaaagaga tgaaagaaag cttacaagct tatgttgaaa
      781 agccaatttc tgttttggaa acgggttcca ttattcaaac tcacacgggt gagaacgctt
      841 gggctatttt gatacgttac cactcctaaa aaaataaata aaatgggaag aaatagcgtt
      901 tttaacttga cctaaaaggg attttaggat atgattatat ttgttaatta gaaattattt
      961 ggaggaatca ttaacatggc aaacaaacaa gatttgatcg ctaaagtagc agaagctaca
     1021 gaattgacta agaaagactc agcagcagca gttgaagctg tatttgcagc agtagctgac
     1081 tatcttgcag ctggtgaaaa agttcagttg atcggttttg gtaactttga agttcgtgag
     1141 cgcgcagaac gtaaaggtcg caacccacaa actggtaaag aaatgacaat tgcagcttct
     1201 aaagtaccag cattcaaagc tggtaaagct cttaaagacg ctgttaaata atcagtcttt
     1261 aaaaagccta ttgtatcaag ctttctagct tggtcagtag gctttttaat tatgaaatct
     1321 agtaataaat agagttaaaa agttgaatgt tccgaaaata ttg
//
LOCUS       DAVLMQ010000143         1362 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.144, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000143 DAVLMQ010000000
VERSION     DAVLMQ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1362
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.144"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            88..1266
                     /locus_tag="VXF95_002241"
     CDS             88..1266
                     /locus_tag="VXF95_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082685.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDCQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKNGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT          464 a          269 c          287 g          342 t
ORIGIN      
        1 acaacctcaa aacagtgttt tgagctgact gcgactagct ttctagtttg ctctttgatt
       61 tttattgagt attagaaagg agacctcatg acacttccag ttagaaaatc cctgcacgat
      121 gcagttttac aggcttcgaa agcggatact tgggaacaag ctaccaagga atggaatgaa
      181 gtttccttga tttttaacgg tatcggccgt agcaattgtg tctgtggaaa tgccatcaaa
      241 tacgcttatg aactctttaa cggtgtcaca ggccaacgcc tctttccaat tggtagcgac
      301 tgtgttcgtc attttcatcg attgtccctt gaccagcaat tggaagagga agaaaaactg
      361 ctcagaaagg ttgaaaatct aaccagaaaa gctcagaaaa aggaaaaaat caaggtcaat
      421 aaaagtgact ttgacgagcg acttctaaaa tggctctggg aaaaaggtgt tttcaaaccc
      481 aatcgtggca atcaatttgc gcctgagaga gactgccagc ttttcctaga agtctttcag
      541 ggaggaagtt ggaccaaggc ggaaccaaag aaaaaggctc ggatggaaga agtccttgaa
      601 aagtgtatca aacccttttt acttgggaaa tcggatgacc aactctacct tgtcaagcta
      661 ggcaaggaga aaattgacta cgaacaagaa ctccgtatcc aggcagagaa agaacgcaag
      721 aagagggata aaatcgccaa gcaatatgca gacaatctgg ttctagccat gggacccgca
      781 gagcgtgctt atcaagatta ctttggcttt acagagaccc tgactcaaga agaacgcaag
      841 tgggaaaaaa ttctttttgg taaaaataga gcagaacggg ctatcaaggc caaacaatac
      901 caaaaagagc tggaaaaaga ccaacgaatt gccagtcagg atccaattga aagaaaacag
      961 aagcagactt ggctcctcaa ttcctatttt cgtgagcttc ctgaagaaaa agctcgattt
     1021 tctaggctct tattagaata tcgaaaaaat ggtgaagtac ccttttcaac tgaatacctg
     1081 tcagatcatc tcatcgactt tttctataaa atgaaagcct ttgaatttga aatcgcacca
     1141 gaacaagttc gagattttct aaaaaaaagc ctgcaggaag accatcgctc atcagcacaa
     1201 ggaagctgga tagaaggaat tctcctcaac tgcctcaaac catttttaga acgattagtg
     1261 atatgagtaa cacctaccgt gtaaatttca tggtaggtgt tattgtacct caaaataata
     1321 taaaacaaag tatgaaagcg catctcaatt ttaagacttt tt
//
LOCUS       DAVLMQ010000144         1202 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.145, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000144 DAVLMQ010000000
VERSION     DAVLMQ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1202)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1202)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1202
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.145"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..104
                     /locus_tag="VXF95_002242"
     CDS             <1..104
                     /locus_tag="VXF95_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HEV1082686.1"
                     /translation="TFKMFSTTYRNHRKRFGLRMNLIAGIINHELGF"
     gene            complement(842..1102)
                     /locus_tag="VXF95_002243"
     CDS             complement(842..1102)
                     /locus_tag="VXF95_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082687.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELEPVKSTILQNNDISLDQNEIFEILKNFLDG"
BASE COUNT          404 a          224 c          198 g          376 t
ORIGIN      
        1 aaacgtttaa aatgttttca acaacctatc gaaatcatcg taaacgcttt ggattacgaa
       61 tgaatttgat tgctggtatt atcaatcatg aactaggatt ctagttttgc aggaagtcta
      121 ttatatatgc acagacatat gaaatctttt tgagacagca gttatgatat atttatccat
      181 tcacaacatc ttctgtacta atactacaat attggtacat tttgattaca caatcgtttc
      241 aaaaaatatg atggaagcct gagtatttta tagtaattcc cttcctatca actagatcaa
      301 ccagttgagt gttgaatgtt gaaacaccct agcctcagca aaggactatg atcagcattt
      361 cctagccaat aggacgctcc aaatcaccta ttctaagtcc atcactagct tggtcagtaa
      421 gatacagact gcaaggcgag actgatgtgg ttgatgagat tttggaagag tattacaatc
      481 atagattcac cagtagactt gaccgcagat ttaactatag tagattgaaa ctagaatagt
      541 acacctctac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc aatttgtcct
      601 gttctcgttt cattttacta tactaaaaaa ccacctgaaa caaatcaagt gactagagga
      661 taaaaacaaa aactgggcaa aaagttttga aaagcaaaaa acgcataata tcaggtcttg
      721 aaaaaccttg atactatacg tttgattgtg ggaagattga cttcattttc tcctgaaatt
      781 gaagtttttt ctagtttcca gatatagacg aattcaatat agccatctcg ctacaattat
      841 tttaaccatc gagaaaattt ttcagaattt caaaaatttc attttgatcc aatgaaatgt
      901 cattattttg aagaatagtt gacttcacag gctctaattc tatcacaaag cggtgcatgt
      961 ctgcttttac cgcactactt gatgttatag ccgataactt ttcatctcct agcaaggaag
     1021 ctgtcaaacg ggtaaggtca ttcaaatgct ttttaatgga cttacttaaa ccttgagcac
     1081 ctgtggcaga gcgctccctc atatccagcc aagctttagc cttaaaaata attaatactc
     1141 aatgaaaatc aaagagcaaa ctaggaagct agctgcaggc tgctcaaaac actgttttga
     1201 gg
//
LOCUS       DAVLMQ010000145         1188 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.146, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000145 DAVLMQ010000000
VERSION     DAVLMQ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.146"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>1188)
                     /locus_tag="VXF95_002244"
     CDS             complement(<1..>1188)
                     /locus_tag="VXF95_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000049683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HEV1082688.1"
                     /translation="LTTTEYGFYDLVYTTIQLLVPILTLNISEAVMRFLMKEDVSKKS
                     VFSIAILDIFLGSIIFCLLLLVNQIFSLSELISQYSIYIMVIFAFYTLNNFLIQYSKG
                     IDKIGVTAISGVISAAVMLSMNILLLVVLNWGLLGFFIANICGYVIPCVYIIVKLKLW
                     DLFELKIDRSLQWEMIYYTLPLILNTLSWWVNNTSDRYIITVIIGIQASAIISVAYKI
                     PQIFSTISAIFIQSWQISAIKIQEEKEGNTFISKMLLYYNALLLIIASGIILFVKPIS
                     NILFGASFYSAWTLVPFLIISSLFNAISGYIGAIMGAKMDTKNIAKSALVGMIANVFL
                     NIVLTFLMGLQGITISTMIASFLIFYMRKDSVEEIAPETYRAIYLSWFLLVVEASLLV
                     YIDF"
BASE COUNT          468 a          205 c          144 g          371 t
ORIGIN      
        1 aaaatctata taaaccaaaa gactagcctc aaccactaac aaaaaccacg aaagataaat
       61 agctctatat gtttctggag caatttcttc aacactatct tttctcatat aaaaaataag
      121 aaaactagct atcatagttg agattgtaat cccctgtagt cccattaaaa atgttaatac
      181 aatatttaaa aaaacattag ctatcattcc aaccaaagca gatttagcaa tatttttagt
      241 atccatttta gcgcccatta tcgctcctat ataacccgaa atcgcattaa acaaactgct
      301 aataattaaa aacggtacaa gcgtccacgc tgaataaaat gaagctccga agagtatatt
      361 agagattggt tttacaaata gaatgatacc gctcgctata atcagcaaga gtgcattata
      421 atataaaagc atttttgata taaaggtgtt accttctttt tcttcctgaa tttttattgc
      481 agatatttgc cacgattgaa tgaatatagc gctaattgtg gaaaaaattt gtggaatctt
      541 ataagcaact gaaataatcg cactagcttg tatacctata attactgtta taatatacct
      601 atctgaagtg ttattaaccc accaacttaa agtatttaaa atcaaaggta aagtataata
      661 tatcatttcc cactgtaacg atctatcaat tttaagttca aataaatccc ataattttag
      721 ttttactatt atatatacac aaggaatgac atacccacaa atatttgcga taaaaaaacc
      781 tagtagtccc caatttaata ccactaacaa taaaatattc atcgaaagca taactgctgc
      841 acttatgact ccagagatag ccgttacacc tattttatca atccctttag agtattgtat
      901 caaaaaatta ttaagtgtat aaaaagcaaa aatcaccatg atatatatgc tatattgaga
      961 aattaactcc gataaagaaa atatttgatt gaccagtagt aacaaacaaa aaataataga
     1021 ccctaaaaat atatcaagta ttgcaatcga aaaaactgat ttttttgaaa catcttcttt
     1081 cattaaaaat ctcataactg cttcagatat attcaatgtc aggattggta caaggagttg
     1141 aattgttgta taaaccaaat cataaaaacc atactctgtc gttgttag
//
LOCUS       DAVLMQ010000146         1174 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.147, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000146 DAVLMQ010000000
VERSION     DAVLMQ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1174
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.147"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            17..459
                     /locus_tag="VXF95_002245"
                     /pseudo
     CDS             17..459
                     /locus_tag="VXF95_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001826702.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
     gene            497..799
                     /locus_tag="VXF95_002246"
     CDS             497..799
                     /locus_tag="VXF95_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HEV1082689.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            807..>1174
                     /locus_tag="VXF95_002247"
     CDS             807..>1174
                     /locus_tag="VXF95_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HEV1082690.1"
                     /translation="MNYEASKQLTDARFKRLVGVQRTTFEEILAVLKTAYQLKHAKGG
                     RKPKLSLEDFLMATLQYVREYRTYEEIAADFGIHESNLIRRSRWVEVTLVQSGVTISR
                     TPLSSEDTVMIDATEVQINRP"
BASE COUNT          382 a          211 c          237 g          344 t
ORIGIN      
        1 ctttgacaaa aaccttgtgt tttgcttaga agcggataat caagaataac tttttgatca
       61 ggtagcaagc ttgttggaag aacgagaaat tgtcactcca acttatcgtg aagccttgat
      121 cacgcgtgaa aagtcatttc caactggttt agatatgaaa tttttaggaa aggacttgca
      181 aatgtaatga ttcctcacac agatattgtt cataatctag ctgagaaagt ggtggttgtt
      241 cgattagaga aatcggtgac tttccataat atgattgcgc caggtaagga agtagaagta
      301 tccttgctct tctttatcat caataattca agttcaagtc aaacgaacat tcttgctcag
      361 ttgatggact ttttcacagg aaatggacat cttgaagacc tatcaaaaat ttccgaacca
      421 gaaaaacttt atgcttatat agatgaagca atcgcttaat cttgtctatt aaaaaataaa
      481 atcggaggaa gtctatatga ttaaaattct tgctgcctgc ggtgcaggtg ttaactcaag
      541 tcaccaaatt aaaagtgctc tagaagaaga actttcaaac cgtggttatg atgttcactg
      601 tgatgcagtc atggtgaaag atgtaaacga agaccttatg aaaggttacg atatctttac
      661 accaatcgct gcaacagacc ttggttttga accaggtatc ccagttatcg aagctgggcc
      721 aatcttattc tgtatcccag caatgagcgt tccagtattt gacaatatta gacttcctgc
      781 gaaacaaaat atggtatagt agttccatga attatgaagc aagtaaacaa ctaactgatg
      841 cacgatttaa gcgtcttgtt ggtgttcaac gcacgacttt tgaagagata ttagctgtat
      901 taaaaacagc ttatcaactt aaacacgcaa aaggtggacg aaaacctaaa ttaagcctag
      961 aagactttct tatggccact cttcaatatg tgcgagaata tcgaacttat gaagaaattg
     1021 cggctgattt tggtatccac gaaagcaact taatccgtcg gagccgatgg gttgaagtaa
     1081 ctcttgttca aagtggtgtt acgatttcaa gaactcctct cagttctgag gacacggtaa
     1141 tgattgatgc gacggaagta caaatcaatc gccc
//
LOCUS       DAVLMQ010000147         1143 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.148, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000147 DAVLMQ010000000
VERSION     DAVLMQ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.148"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..212)
                     /locus_tag="VXF95_002248"
                     /pseudo
     CDS             complement(1..212)
                     /locus_tag="VXF95_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            complement(225..974)
                     /locus_tag="VXF95_002249"
     CDS             complement(225..974)
                     /locus_tag="VXF95_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HEV1082691.1"
                     /translation="MSNNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSELKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPCVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
BASE COUNT          403 a          217 c          120 g          403 t
ORIGIN      
        1 taatttcaga aaatgtatca aaaaaagtaa tatttaagtt attctcgcaa aaaaacttca
       61 taagctcttc atttttagat ggaagaatgc ccttttttta aattatttat ttttacagaa
      121 tctatatcat atgcaacaac tttatattta gatgcaaata gtaacgcgta ggccagccca
      181 acatgcccca aaccaattac tgctatattc ataaaactac ttccttattt cttaatccaa
      241 aatctaatag aataagctgc cccattcctt aaatacaact ctttaatatt gtttaaaagt
      301 ttttcaactg atttccagat tatcaaaatc tgagatttat agcacaatat tgatgatatt
      361 ctatcaatat aatgtttttc atcaagttcc tcttgataca tttttaattc tttagttttt
      421 cccatataac taaccatact actatcactt acacatggga agtcctcata atatattact
      481 ttataacgca taaattcaag cgcccttcca atactattca caaaaacatg atcaacatgg
      541 tcaccaagtg aaagcggaca atatacgaca catttgtcgt ctaaatgcat taacagctct
      601 tttatgatat cattctttaa tgtgtcctca ttttttaatt cactatagat atgacggtat
      661 agaaaattgc catttctatc tttcctatag agacattcat agtacgataa gtgtctaaaa
      721 tcacattgta gacgttcaca agctaacctg tcttctttct tcctttcttc aatcggatat
      781 ttcccaaggt tacacaactt atgaaattgc ttagcagagg gctgtagctg ttggctcaaa
      841 gggtaaccag aaaatatagt aataacaagt acaatttctc cttctgaagt taattttgaa
      901 atataatcac cacaggaaaa aattgcgtca tctaaatgtg gagataaaaa gatatactta
      961 gtattgttac tcataaccat tccctctaca atttatctaa aaactcacta agtgtctgat
     1021 taaattccac atcatcaaaa aaattcacct tattcttaat aatgaatatt tcgttaaata
     1081 aacatatata taaatatttc aatatccttt caatatcctt tcaatatcat cctctaaatt
     1141 ctc
//
LOCUS       DAVLMQ010000148         1126 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.149, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000148 DAVLMQ010000000
VERSION     DAVLMQ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1126
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.149"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            74..652
                     /locus_tag="VXF95_002250"
                     /pseudo
     CDS             74..652
                     /locus_tag="VXF95_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            665..835
                     /locus_tag="VXF95_002251"
     CDS             665..835
                     /locus_tag="VXF95_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082692.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
BASE COUNT          407 a          136 c          215 g          368 t
ORIGIN      
        1 tttggattac gaatgaattt gagtgctggt attatcaatc atgaactagg attctagttt
       61 tgcaggaagt ctattatcaa aaataccatc aggattatat aagattgata caggaaaagt
      121 tttatttgat ggtgtaaata ttaatcaaat agataaaaaa atattaagtc aaaatttagg
      181 agtagttcca caggattcgt ttttattgaa cagaagtatt cttgataaca taactttaaa
      241 gcacgaagtt acttcacaaa agatagagga agtttgtaaa gcagttcaaa tctatgatga
      301 aatcatggct atgccgatga aatttaatac tatcatctca gagatgggtt caaatatttc
      361 aggtggtcaa agacaacgga tagcactggc acgtgcatta ataaataatc ctagtattgt
      421 aattttagat gaagcaacta gtgctttaga cactattaat gaggaaagaa taacaaagta
      481 tataaaaagt cagggctgta ctcaaataat tgtagctcat agattgtcaa cgattaagga
      541 tgcggatatt attgttgtaa tgaaaggtgg taagattgtt gagtcaggaa atcataagta
      601 cttaatggat cttggtggag agtactacag cttatataca aaaaggaaat gaggtgtaaa
      661 gaaaatgaag aaagaaaatg aatatgtaat tttaacaaca gcctcactag gggtgatgat
      721 tggaatagtg tttgcaattt ttttagattt tccagttgaa tatggtattt ctttaggctt
      781 attgaatgga atagtattgg gttcgctgat tgtttacaaa aacaataaga attaagcata
      841 attttttgct gtaaactaag gagtagagat ggctatagtt gaaattataa atctaacaaa
      901 aagctttaaa gatattgaag ttattcataa cacttaaata atagagcaac tacagtagta
      961 gcttaaaaac atgattaaat cgctattctt aggagtagcg gtttttcttt ttgtttaata
     1021 ctctttgaaa atctcttcaa accacgtcag ctttgccttg ccgtactcaa gtacagcctg
     1081 cgactcgctt cctagtttgc tttttgattt tcattgagta taaaaa
//
LOCUS       DAVLMQ010000149         1121 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.150, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000149 DAVLMQ010000000
VERSION     DAVLMQ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1121)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1121)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1121
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.150"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..585
                     /locus_tag="VXF95_002252"
     CDS             <1..585
                     /locus_tag="VXF95_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082693.1"
                     /translation="KEKDLVKHIAILPQSPIIPESITVADLVSRGRFPYRKPFKSLGK
                     DDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSILLLDEPTTYLDI
                     SYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILND
                     KLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVNS"
BASE COUNT          461 a          177 c          179 g          304 t
ORIGIN      
        1 aaagaaaaag atttagtaaa acacatagct atattacctc aatctccaat aatccctgaa
       61 tcaataacag tagctgatct tgtaagccgt ggtcgtttcc cctacagaaa gccttttaag
      121 agtcttggaa aagatgacct tgaaataata aacagatcaa tggttaaggc caatgttgaa
      181 gatctagcaa ataacctagt tgaagaactt tctgggggtc aaaggcaaag agtatggata
      241 gctctagccc tagcccaaga tacaagtatc ctacttttag atgagccaac tacttacttg
      301 gatatctcat atcaaataga actattagac ctcttgactg atctaaacca aaaatataag
      361 acaaccattt gcatgatttt gcacgatata aatctaacag caagatacgc tgattaccta
      421 tttgcaatta aagaaggtaa acttgttgca gagggaaagc ctgaagatat actaaatgat
      481 aaactagtta aagatatctt taatcttgaa gcaaaaatta tacgtgaccc tatttccaat
      541 tcgcctctaa tgattcctat tggcaagcac catgttaact cttaataatt gaatattgga
      601 attcatttaa aagtcgcaaa ttttgaactg accctcaaaa gttaggccaa aaaactaact
      661 aaaggaggtc agttttttaa tggcaaatac agcacagaat ttaagataaa attagtaaaa
      721 gaatatcatg aatgaaaaat aggatataga gaataacagc aatattaaaa agatcaggac
      781 tgataataaa caaaaagaaa gtacaacgac tagttcaaaa gctaaaactt caagtaaaaa
      841 gttattcaag aaaatctaga aaatactcat cctacaaagg acaggtagga aaaatatcag
      901 acaacaaaat aaaaagaaat atttattacc gaaaaaaagg ggaaatcgag tcaagtacca
      961 acaggctcat ctattccaaa aagatattta ctcgatggaa aaactcctag aattagtgct
     1021 acaaatattg acaatggtat cttaggttac tacgaagata tagatgataa aaattataga
     1081 gtttttgaaa attttatatc tgtttcattt ttaggagcag t
//
LOCUS       DAVLMQ010000150         1062 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.151, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000150 DAVLMQ010000000
VERSION     DAVLMQ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1062)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1062)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1062
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.151"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="VXF95_002253"
     rRNA            complement(<1..96)
                     /gene="rrf"
                     /locus_tag="VXF95_002253"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(173..>1062)
                     /locus_tag="VXF95_002254"
     rRNA            complement(173..>1062)
                     /locus_tag="VXF95_002254"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          246 a          312 c          223 g          281 t
ORIGIN      
        1 cacagggggc aacccccaac tacttccggc gttctagggc ttaacttctg tgttcggcat
       61 gggtacaggt gtatctccta ggctatcgtc acttaactct gagtaatacc tactcaaaat
      121 tgaatatcta ttcaacttaa gaaaaccgtt cgctttcata ttctcagtta ctttggataa
      181 gtcctcgagc tattagtatt agtccgctac atgtgtcgcc acacttccac ttctaaccta
      241 tctacctgat catctctcag ggctcttact gatatataat catgggaaat ctcatcttga
      301 ggtgggtttc acacttagat gctttcagcg tttatccctt ccctacatag ctacccagcg
      361 atgcctttgg caagacaact ggtacaccag cggtaagtcc actctggtcc tctcgtacta
      421 ggagcagatc ctctcaaatt tcctacgccc gcgacggata gggaccgaac tgtctcacga
      481 cgttctgaac ccagctcgcg tgccgcttta atgggcgaac agcccaaccc ttgggaccga
      541 ctacagcccc aggatgcgac gagccgacat cgaggtgcca aacctccccg tcgatgtgaa
      601 ctcttggggg agataagcct gttatcccca gggtagcttt tatccgttga gcgatggccc
      661 ttccatacgg aaccaccgga tcactaagcc cgactttcgt ccctgctcga gttgtagctc
      721 tcgcagtcaa gctcccttat acctttacac tctgcgaatg atttccaacc attctgaggg
      781 aacctttggg cgcctccgtt accttttagg aggcgaccgc cccagtcaaa ctgcccgtca
      841 gacactgtct ccgataggga tcacctatct gggttagagt ggccataaca caagggtagt
      901 atcccaacag cgtctccttc gaaactggcg tcccgatctc ttagactcct acctatcctg
      961 tacatgtggt acagacactc aatatcaaac tgcagtaaag ctccatgggg tctttccgtc
     1021 ctgtcgcggg taacctgcat cttcacaggt actaaaattt ca
//
LOCUS       DAVLMQ010000151         1028 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.152, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000151 DAVLMQ010000000
VERSION     DAVLMQ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1028)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1028)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1028
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.152"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            36..908
                     /locus_tag="VXF95_002255"
     CDS             36..908
                     /locus_tag="VXF95_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HEV1082694.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVVLLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQERVSKDKLV"
BASE COUNT          311 a          186 c          239 g          292 t
ORIGIN      
        1 tttttattgt ataataaaag tgagaggaaa aaaggatgaa agtgattaat caaaccttat
       61 tagaaaaagt tattattgaa cgttctcgtt caagtcataa aggagattat ggtcgtctgc
      121 tgctgcttgg tggtacttat ccttatggag gtgccatcat catggctgct ttagcagctg
      181 taaaaagcgg tgcaggattg gtgaccgttg gaacggacag ggaaaatatc ccggctctgc
      241 acagccattt acctgagcct atggcctttt ctcttcaaga ccagcaattg ttaaaagagc
      301 aattggagaa ggcagaagtt gtcttgctgg ggcctggttt acgagacgat gcttctggag
      361 aaaatctagt aaaacaggtc tttgttaatt taagccaaaa tcagattttg attgtagacg
      421 gaggtgcctt gaccattctt gctaggacaa gtttgtcatt tccctcaagc cagcttatcc
      481 taactcctca ccaaaaagaa tgggaaaaat tatctggaat tacgattgaa aagcaaaagg
      541 aagatgcaac ggctagtgtt ctgacttcct tccctcaagg aacaattttg gtggagaaag
      601 gcccagctac tcgtatttgg gaagttggcc aatctgatta ttaccagtta caggttggtg
      661 gtccttatca ggcgactggg ggaatgggag atactctggc tgggatgatc gcaggatttg
      721 taggccaatt ccgacaggcc agtctctacg agcgtgtggc agtagcgacc catcttcatt
      781 cagccatagc ccaagaacta tctcaagaaa attatgtggt cttaccgacg gaaatcagca
      841 ggtatcttcc caaaataatg aaaattattt gtcaacaaga gagggtaagt aaagataaac
      901 ttgtttaaaa tagacagata aatctacttc cttctcttaa tttatgattc ttgaaatgcg
      961 cctgctttaa ggctaaacta gacgtatcaa agttaagagt ttgtttttgt aactggaaag
     1021 agatgaac
//
LOCUS       DAVLMQ010000152          994 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.153, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000152 DAVLMQ010000000
VERSION     DAVLMQ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.153"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..335
                     /locus_tag="VXF95_002256"
     CDS             <1..335
                     /locus_tag="VXF95_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="protein kinase"
                     /protein_id="HEV1082695.1"
                     /translation="LRKETQIEEKKLPLFGTPGFYETNLNLLNNQPEDIMGLVLLLYW
                     SQNLDDFNVFSKMSFLEAMEYAMNFNSRRLDTLDKSDWLYDIYKKAFNYKYDTFSELK
                     KDFIEVLK"
     gene            349..>994
                     /locus_tag="VXF95_002257"
     CDS             349..>994
                     /locus_tag="VXF95_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HEV1082696.1"
                     /translation="MNCFLKMNNVSVRYDDVIALKDITLQINKGDFIGLLGSNGAGKS
                     TLINSIVGFQEIYLGEIEYCDKDLIVSSQPFAHLGFTPQTTVIDFYTTVKDNVILGLN
                     LAGKFGKNAEKLCQIALEIVGLADKKNNLVETLSGGQLQRVQIARAIAHNPDFYILDE
                     PTVGLDTESAEKFLMYLKDKSLEGKTIIISSHDINLLEKFCKKILFLQNGSISFF"
BASE COUNT          350 a          114 c          184 g          346 t
ORIGIN      
        1 ccctaaggaa agaaactcaa attgaagaaa aaaagttgcc tctatttgga actccagggt
       61 tttatgaaac caacttaaat ttattgaata atcaaccaga ggatattatg ggattggttt
      121 tgttattata ttggagtcag aatttagatg attttaacgt cttttcaaaa atgagttttt
      181 tagaagcgat ggagtatgca atgaatttta attcgcgtcg cttagacaca cttgataaat
      241 cagattggct ttatgatatt tataaaaaag cgttcaatta taaatatgat actttttctg
      301 aattaaaaaa agattttata gaggtattaa aataaaggta ggggtgttat gaattgtttc
      361 ttgaaaatga ataatgtaag tgttcgttat gatgacgtaa tagctttaaa agatataact
      421 ttacaaataa ataagggaga tttcattggc ttattaggtt caaatggtgc aggtaaatct
      481 acgttaatta attctattgt aggttttcaa gagatttatt taggagaaat agagtattgt
      541 gataaagatt tgatagttag ttctcaacct tttgctcatt taggctttac tcctcaaacc
      601 acagtaattg atttttatac tactgtgaag gacaatgtaa tattggggct gaaccttgct
      661 ggaaagtttg ggaaaaatgc tgagaagttg tgtcaaatag ccttagaaat tgttgggtta
      721 gctgataaaa aaaataattt ggtagaaaca ttgtcaggtg gacaactgca acgcgtccag
      781 attgctagag caatagctca taatccagat ttttatattt tagatgaacc taccgttggt
      841 ttagatactg aatctgccga aaaattttta atgtatttaa aagataagag tttggaagga
      901 aaaactatta tcatatcttc acatgacata aatctactcg aaaagttttg taaaaaaata
      961 ctttttttac aaaatggctc catatcattt tttg
//
LOCUS       DAVLMQ010000153          990 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.154, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000153 DAVLMQ010000000
VERSION     DAVLMQ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 990)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 990)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..990
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.154"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(1..413)
                     /locus_tag="VXF95_002258"
                     /pseudo
     CDS             complement(1..413)
                     /locus_tag="VXF95_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            complement(659..970)
                     /locus_tag="VXF95_002259"
     CDS             complement(659..970)
                     /locus_tag="VXF95_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082697.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
BASE COUNT          307 a          201 c          163 g          319 t
ORIGIN      
        1 attttacgac gagcaccaaa caactgctca ttttcagatg gtgtaccata gtaaaatcct
       61 gtagccagtt cacgttgggc aaccttccac atctcgtcca ccaagtcttg tttgatagct
      121 tcaaactttt caggactttc aagataggca tccacagccg ccttgtagca gttggttact
      181 gttaatacat agtgaataga ctccatacgt ccttcgattt ttagactgtc cacgccattt
      241 tcaatcatat ctggaatgtg gtcaatcata gacatgtcaa cggctgacat tgaaaattct
      301 tctggaatct caccctgcaa actcttacgt tctttcccaa atggcatatc gtaaaggtcg
      361 tacttccaac ggcatgactg agaacatcca ccacggttgg catcacgcat actctagacg
      421 gattgttttg acaattctaa tcttttagac tttgcataat aactgttaaa cagttgaaaa
      481 ttgacccagt tttaacaagt agtcaaaata ccagataaag gaaaaaagtc tttaaaatct
      541 taaaaacgca tagtatcagg tattgaacaa tcttgatatt atgcgtttta ttgtgggaag
      601 atttacttca ttttctcttg gaattgagtt ttctcctact tcaaaactag atgatttgct
      661 atttaaaata gcgttcctta tgattttggc aacctggatt aaagcgagaa aaacaaaagg
      721 ggcaacttaa gctttcttta tattgcttat atgttagtag ttttagacaa acaccacata
      781 aaataggctt atcctgtatc aaagataagg gatacggctc aaaagggtga ttttctaatg
      841 aatcatgaca ccgataacaa gcataatact ttttacaatc atagcattgt aaagcaataa
      901 tatccagctt gctatggtaa tgaatgcatc ttgtttgctt atccactaag aaaccctgtg
      961 cctctatcat ttccttttcc tttcttaagc
//
LOCUS       DAVLMQ010000154          919 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.155, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000154 DAVLMQ010000000
VERSION     DAVLMQ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.155"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..724
                     /locus_tag="VXF95_002260"
                     /pseudo
     CDS             1..724
                     /locus_tag="VXF95_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(843..916)
                     /locus_tag="VXF95_002261"
     tRNA            complement(843..916)
                     /locus_tag="VXF95_002261"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(880..882),aa:Asn,seq:gtt)
BASE COUNT          304 a          200 c          141 g          274 t
ORIGIN      
        1 tcgctgaaac ttctatcgtc aagaagaatc atcaaattcc ttgtatcatc aaccaaaaga
       61 ttgctcagaa gctaattgaa aagacttcta tgaccgacat tgattatcag ttgtctattt
      121 caactgtcat tcgcaagatc aatgattttc actttgagca tgatttttcg cgtcttcctg
      181 agattatgtc ctaggacgtt gaaacagtcc agggagtgac tatttcaatc gggagatgga
      241 gatgagcttt attgctcagg actttgataa gctcaatatc ataactgttc ttgagagcag
      301 aacacaagcc atcatacgaa atcccatgaa tacaaggcta tcaagcgcta ctggagctca
      361 ttcaacaaga tagtcagaaa ctgagtgata aacgatttta tcgccctact tttcgtatgc
      421 acttgactaa taaagaaatt ctagataaac ttttgagcta ttcgaagact tgaaacacca
      481 ctataatctc tatcagctat aatctctatc agctcttgct tttccacctc tttttcagac
      541 tctgtttaaa accttcctca aagataaaga aaaaatcgtc aacggccttc aattacctta
      601 ttccaacgcc aaactggaag ccaccaataa tctcatcaaa cttatcaagc acaatgcctt
      661 tggttttagg aactttgaaa acttcaaaaa agaaaggacg aaatttgtcc tttctcaagc
      721 ttagcttttc ttcaacccac tacagttgac aaagagccac tatttttggt tcattttact
      781 ataacacgaa atagattatt attacataat aaaaaagagg tctaaacctc ttaactaaat
      841 tactccgcca gtaggactcg aacctacgac atcatgatta acagtcatgc gctactacca
      901 actgagctat ggcggatta
//
LOCUS       DAVLMQ010000155          887 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.156, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000155 DAVLMQ010000000
VERSION     DAVLMQ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..887
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.156"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..887
                     /locus_tag="VXF95_002262"
                     /pseudo
     CDS             1..887
                     /locus_tag="VXF95_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
BASE COUNT          269 a          188 c          163 g          267 t
ORIGIN      
        1 ccaaactgga ctacgacgcc ccatcttgcc ctgagtgcgg aagtcaaatg aagaaatatg
       61 actttcaaaa accttctaag attccttatc ttgaaacgac tggtatgcct actagaattc
      121 tccttagaaa gcgtcgattc aagtgctatc actgttcaaa aatgatggtc gctgaaactt
      181 ctatcgtcaa gaagaatcac caaatccctc gtatcatcaa ccaaaagatt gcgcaaaagt
      241 taattgaaaa gatttctatg actgatattg cccatcagct ttccatctca acttcaactg
      301 ttattcgtaa gctcaatgat tttcactttg agtgtaattt tagaaatctg cctaagatta
      361 tgtcttggga cgttgaaaca gtccagggag tgactatttc aatcgggaga tggagatgag
      421 ctttattgcg caagattttg aaaagctcga tatcatcact gttcttaagg gaagaacaca
      481 agctgtcatc cgaaatcact ttcttaaata tgatagagcc gtctgatgtc gcgtcaaaat
      541 cattactatg gatatgttta gcccttacta tggcttggct aaacagcttc gctttcaaat
      601 ttctaggctc aggctgaaac agtctcccag actgtttcac tcccgaatgc taaaatcgtt
      661 cttgaacgct ttcacattgt gcaacatctt agccgtgcta tgagtcgtgt gcgtgttcaa
      721 atcatgaatc agtttcatcg aaaatcccat gaatacaagg ctatcaagcg ctactggaag
      781 ctcatacaac aggatagccg taaactgagt gataagcgat tttatcgtcc tacttttcgt
      841 atgcatttac caataaagag attttaaaca agcttttgag ttattca
//
LOCUS       DAVLMQ010000156          789 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.157, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000156 DAVLMQ010000000
VERSION     DAVLMQ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 789)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 789)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..789
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.157"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..259)
                     /locus_tag="VXF95_002263"
     CDS             complement(<1..259)
                     /locus_tag="VXF95_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator BglG"
                     /protein_id="HEV1082698.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLG"
     gene            complement(559..741)
                     /locus_tag="VXF95_002264"
     CDS             complement(559..741)
                     /locus_tag="VXF95_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000842022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HEV1082699.1"
                     /translation="MKSQKIKVSFTQSKIVTPILLVNKTIVWYGAMPLLGKVDEMTIL
                     RLESASIASELVAGLR"
BASE COUNT          264 a          141 c           98 g          286 t
ORIGIN      
        1 tacccaatgt tattttacct aggttaatta ttttttcggt gatgtacacc aactccaaag
       61 gaacgttaat aaacatctct gtaaaacggg tcatattatc tctatttttg agaaaaaaac
      121 ttttctcaat atcaattgga tttactttat ctccagtttt tcttccaaaa gctattcccc
      181 ttccaaaaag aagaatatcg atatcttttt tactttgcgc aattacggca ttgtggttta
      241 gtattcgttt tatgatcata aaatttccct tttaaaataa aaggaaccta cttaaaaaca
      301 tcaagaaact tcttccgatg tgattaaata ggttcctgct cacttgtatt agtgataaca
      361 tccttttatt tcaattttta atggtgacat gaagcttaaa tcattaataa ctctgtaacc
      421 attttcattt taagatattt caatctattt gtcaagtact tatagaaatt tttttatttt
      481 gtgtgattcg aatgtgataa tgacaacagt ctcactaaag aaatgaaaat catacataga
      541 aatttttaaa aattttctct atcgtaaacc tgccactagt tcagaagcta tactagctga
      601 ttccaaacgt aatatggtca tctcatctac cttccctaat aatggcattg caccatacca
      661 aacaatagtc ttattcacca aaagaatagg cgttactatt tttgattgag taaaagacac
      721 tttaattttc tggctcttca actgtgaact acaccccaaa agttagacag aaaaaatcta
      781 acttttggg
//
LOCUS       DAVLMQ010000157          728 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.158, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000157 DAVLMQ010000000
VERSION     DAVLMQ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 728)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 728)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..728
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.158"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>728
                     /locus_tag="VXF95_002265"
     CDS             <1..>728
                     /locus_tag="VXF95_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="catalyzes the formation of UDP-glucuronate from
                     UDP-glucose; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HEV1082700.1"
                     /translation="PTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKLTVPFGFSN
                     KLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVVGDETVEGRKIAELFLSISTHSTA
                     NIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPRI
                     GKFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKP
                     KIVGIYKLGMKYNSDNYKESAILS"
BASE COUNT          269 a           88 c          132 g          239 t
ORIGIN      
        1 ccgacagatt atgatgagaa aattggtagt tttaatacat atgaaatcga acaaacggta
       61 tcgaagattc tgagggtaaa acctaatgga aagattattt taaagttaac agttccgttc
      121 ggcttttcaa acaaattaaa aaggctgttt gatacaaaaa atatcatttt tgtccctgaa
      181 tttttgagag aaggttgttc tatatatgat aatttatatc caagtcgcat agttgttgga
      241 gatgagacag ttgaaggaag aaaaattgca gagttgttcc tttcgattag tactcatagt
      301 actgccaata ttaaaaatgt tatgttagtt tctcctactg aagcagaagc aattaagctt
      361 ttttctaaca cattcttagc tctccgtgtt gcttttttta atgaactaga ttcttttgct
      421 gagaggagaa gtttaaatgc tgaagttgta ataaaaggtg tttgtttaga tccaagaatt
      481 ggaaaatttt ataataatcc ttcttttgga tttggaggat attgtcttcc caaagatact
      541 aaacaattaa aaaaagaatt tatagaaata aatgccccag tgatagaagc gattgatatt
      601 tcaaacacaa atagaaaaca gttcatagtt aaacaaatat tggaacgaaa gccaaagata
      661 gtaggaatat ataaattggg gatgaaatat aattcagata attacaaaga gtcagctatt
      721 ttaagtat
//
LOCUS       DAVLMQ010000158          721 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.159, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000158 DAVLMQ010000000
VERSION     DAVLMQ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.159"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            259..477
                     /locus_tag="VXF95_002266"
     CDS             259..477
                     /locus_tag="VXF95_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HEV1082701.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            481..>721
                     /locus_tag="VXF95_002267"
     CDS             481..>721
                     /locus_tag="VXF95_002267"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HEV1082702.1"
                     /translation="MTLRTEDQVRDYAREVLGFNEVEENINQGTGQITTFNQLGFKGY
                     SDKPDGWYLPKNMNDVAIILETKSEERDISKQIFID"
BASE COUNT          310 a           82 c          124 g          205 t
ORIGIN      
        1 tcttattttg tgatgaaaat ttaatatgta aatctcagac gatagaaatt aaaaactctg
       61 tcgtcttttt tatactcaaa attaggaggt aaaaatggta aggataagag gtcccactta
      121 aaacaattta tggcaaaata aggacggaat aacacaacaa attctctaaa acaaatcact
      181 aaatcaatgt aagattgaat aaaatcaata tttatgctat aattaaataa atctaatgaa
      241 gaaaaaaaga gggatattat ggcacttaac tataaaccat tatggataca gttagcaaaa
      301 aaaggactaa agaaaacaga tgtaatagct atggcaggac ttacaacaaa tgttatggca
      361 caaatgggaa aggataaacc aattacattt aagaatttag aaagaatatg taaggcttta
      421 tcttgcactc ctaatgatat tattagtttt gaagataatt ttagtgacga ggaatagaaa
      481 atgactttaa ggacagaaga tcaagttagg gattatgcaa gagaagtatt aggctttaat
      541 gaagttgaag aaaacatcaa tcaaggtact ggtcaaataa ctacttttaa tcaattaggc
      601 ttcaagggat attcagataa gccagatggt tggtatttac ctaaaaatat gaatgatgta
      661 gcaataatcc ttgaaacaaa atcagaagaa agagatatta gcaaacaaat ttttattgat
      721 g
//
LOCUS       DAVLMQ010000159          677 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.160, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000159 DAVLMQ010000000
VERSION     DAVLMQ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.160"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(200..487)
                     /locus_tag="VXF95_002268"
                     /pseudo
     CDS             complement(200..487)
                     /locus_tag="VXF95_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            486..677
                     /locus_tag="VXF95_002269"
                     /pseudo
     CDS             486..677
                     /locus_tag="VXF95_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          242 a          123 c          115 g          197 t
ORIGIN      
        1 aaaacattga ggaaataata aaaatctatg ggtaatgttc tgaaagtact tttaggttag
       61 gagagaaata taatgatttt tgaaaattga ttcaaaaaat agcgaattgt agaaaacgct
      121 taacaaatgg tgtataatag acttccagcg aaacaaaata tgctacaata aacctatgaa
      181 ttataaagca accttatact catctgtctt cacaaagcat tctagtccat ctccgattaa
      241 cgatggactt tatcatctcc ttctccagtc cttgtatgac atcttccaaa gttcgaaagg
      301 ctttattctt aaatccacgt ttacgaatct ctttccacac ttattcaatg gggttcatct
      361 ctggtgtgta tggaggaata aatgcaaagc caatattagt cggaatcttt aaggcacttg
      421 atttatgcca tatagcattg tccataacga gtaaaatata atcatctgga taagcttgtg
      481 aaagtttggc tgacagtggt tatcaagggc tcatgaagat atatcctcaa gcacaaactc
      541 cacgtaaatc cagcaaactc aagccgctaa cagttgaaga taaagcctat aaccatgcgc
      601 tatctaagga gagaagcaag gttgagaaca tctttgccaa agtaaaaacg tttaaaatgt
      661 tttcaacaac ctatcga
//
LOCUS       DAVLMQ010000160          526 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.161, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000160 DAVLMQ010000000
VERSION     DAVLMQ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.161"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>526)
                     /locus_tag="VXF95_002270"
     CDS             complement(<1..>526)
                     /locus_tag="VXF95_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1082703.1"
                     /translation="IRNHFLKYDRAVRCRVKIITMDMFSPYYDLARQLFPCAKIVLDR
                     FHIVQHLSRAMSRVRVQIMNQLDRKSHEYKAIKRYWKLIQQDSRKLSDKHFYRPTFRM
                     HLTNKEILNKLLSYSQDLKHHYQLYQLLLFHFQNKEPEKFFGLIEDNLKQVHPLFQTV
                     FKTFLKDKEKIVNAL"
BASE COUNT          163 a           88 c          112 g          163 t
ORIGIN      
        1 agggcgttga cgattttctc tttgtccttt agaaaggttt taaagacagt ctgaaaaaga
       61 ggatgaacct gctttagatt gtcctcaatg agtccgaaaa atttctccgg ttccttattc
      121 tgaaagtgaa acagcaagag ttgatagagc tgatagtggt gtttcaagtc ttgtgaatag
      181 ctcaaaagct tgtttaaaat ctctttattg gttaaatgca tacgaaaagt agggcgataa
      241 aaatgtttat cgctgagttt acgactatcc tgttgtatga gcttccagta gcgcttgata
      301 gccttgtatt catgagactt tcgatccaat tgattcatga tttgaacacg cacacgactc
      361 atagcacggc taagatgttg tacaatgtga aagcgatcca acacgatttt agcacatggg
      421 aaaagttgtc tagctaagtc atagtaagga ctaaacatat ccatagtaat aattttgacg
      481 cgacatcgga cggctctatc atatttaaga aagtgatttc gaatga
//
LOCUS       DAVLMQ010000161          521 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.162, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000161 DAVLMQ010000000
VERSION     DAVLMQ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..521
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.162"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(40..>521)
                     /locus_tag="VXF95_002271"
     CDS             complement(40..>521)
                     /locus_tag="VXF95_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HEV1082704.1"
                     /translation="LYGASLFSFLWMYGQRKQVVKVNMKTRMKCLGIGLASLLIISLC
                     FSLIHAQGSTNQTNLIGLQHQVPWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVA
                     LTSVLFALVHHPGTILAWCLYVSLGMFLGMVRYKSDLWGSMGLHLVWNFLVYSLLLF"
BASE COUNT          206 a          108 c           72 g          135 t
ORIGIN      
        1 aaaaactaca gatttatgag ataaatcagg tcacctattt taaaaaagca gcaaactata
       61 aactaaaaag ttccacacca aatgtaaccc catacttccc cataagtcag atttatagcg
      121 caccatacct aaaaacattc caagtgaaac gtacagacac caagctagaa tggttcctgg
      181 atgatgtact aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
      241 caagttccat aaaatttcac gatacagaaa ttcttcaacc atactcgcat tgattaagaa
      301 caataaaaat gaaaaccaag gaacttgatg ttgaaggcca attaaatttg tttgattcgt
      361 gcttccttga gcatgaatca ggctaaaaca tagacttata atcagtagac tagctagtcc
      421 aataccaagg catttcatcc tagttttcat attgaccttg accacttgtt ttcgttgacc
      481 atacatccat aaaaaagaaa aaagagacgc accatagaga a
//
LOCUS       DAVLMQ010000162          488 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.163, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000162 DAVLMQ010000000
VERSION     DAVLMQ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.163"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            189..440
                     /locus_tag="VXF95_002272"
     CDS             189..440
                     /locus_tag="VXF95_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000098314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082705.1"
                     /translation="MSSQMKAFLNELQGNMEVVGEFFDNPEKVIRKFGIVGREKEALL
                     IRDLNDMDDYALSIQNSVASPSGAHSSTCHFVRQDLQSA"
BASE COUNT          184 a           53 c           87 g          164 t
ORIGIN      
        1 taatttacta atttcaaaac aattttttga gatatatgta attaaatcta aattaagctt
       61 taaaaaatta tttttagcaa tttgattttg aaagtgtcat gcagcaatat gaaagcgtag
      121 aatagaggtg tttccaatgt acaagtaagt tttgattcca aataaagtaa tagaaaagga
      181 gctatataat gagtagtcaa atgaaagctt tcttgaatga acttcaagga aatatggaag
      241 ttgttggaga attttttgat aatcctgaaa aggtaattag aaaatttgga attgtcggaa
      301 gagagaagga agcattgcta atccgtgact taaatgatat ggatgattat gctctttcaa
      361 ttcaaaatag cgttgcatcg ccttctgggg cacatagtag cacttgccat tttgttagac
      421 aagatttaca atccgcataa ttgttaatat ataaaacata aaatttcaat tttcaattag
      481 ggataata
//
LOCUS       DAVLMQ010000163          461 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.164, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000163 DAVLMQ010000000
VERSION     DAVLMQ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.164"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            13..276
                     /locus_tag="VXF95_002273"
     CDS             13..276
                     /locus_tag="VXF95_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001823653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082706.1"
                     /translation="MKENGEFIRCKNVSDDFYMYRDVQKRPVIVNGRRQFKDVETVWA
                     FNQWGGTIATINVAVLLNHEFYIMKFDAEGNPDWTVPTVEPKE"
     gene            285..>461
                     /locus_tag="VXF95_002274"
     CDS             285..>461
                     /locus_tag="VXF95_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holin"
                     /protein_id="HEV1082707.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGL"
BASE COUNT          138 a           80 c          112 g          131 t
ORIGIN      
        1 gctttgcgct acatgaaaga aaatggagag ttcattcgtt gcaagaatgt aagcgatgac
       61 ttctatatgt atcgtgacgt tcaaaaacgt cctgtgatcg taaatggccg tcgccaattc
      121 aaggatgttg aaaccgtttg ggcgttcaat cagtggggtg gtacaatcgc aacaatcaac
      181 gtagccgttc tgttgaatca tgaattctat atcatgaaat ttgatgcaga gggcaatcct
      241 gactggacgg ttccaacggt agaacctaaa gaataggagg ttgtatgcaa attgaatttt
      301 tcaattttct aagaagtgtc gtacagactg aagatggttt ggtattgtac gctctagcac
      361 tgattgtctc aatggaaatc attgattttg tgacagggac gattgcggca attatcaatc
      421 ctgacatcga gtacaagagc aaaatcggca tcaatgggct a
//
LOCUS       DAVLMQ010000164          424 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.165, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000164 DAVLMQ010000000
VERSION     DAVLMQ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..424
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.165"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            166..369
                     /locus_tag="VXF95_002275"
     CDS             166..369
                     /locus_tag="VXF95_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082708.1"
                     /translation="MNTEQLNQALQMTISEMSTTSTNSMITSNILSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
BASE COUNT          188 a           73 c           73 g           90 t
ORIGIN      
        1 gttccttact taatcaaggc tattcaagaa ttaaatcaaa aaatagaaaa aatggagaaa
       61 acaatagcat gaataacaac atgttgacca atatcgcact taaagcaatt taggagcttg
      121 ctcttgaaaa tagaaaacga acacacagat tggagaactt agaaaatgaa cacagaacag
      181 cttaaccaag ccttacaaat gacaattagt gaaatgtcaa caacttcaac aaattcgatg
      241 attacaagta atatcttgag tattcagttg aatgagcaaa gggaagagaa tcaaagactt
      301 caagcacgag tggatgagct ggaagctctg cttgatgaac aaactaaacc agcagacaaa
      361 ggagaataga catggcagaa acaattcaaa acacagataa cttactagac cttacaaaaa
      421 tcac
//
LOCUS       DAVLMQ010000165          379 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.166, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000165 DAVLMQ010000000
VERSION     DAVLMQ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.166"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>379
                     /locus_tag="VXF95_002276"
     rRNA            <1..>379
                     /locus_tag="VXF95_002276"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          109 a           89 c          104 g           77 t
ORIGIN      
        1 ctgccaagaa aagcttctag cgtttaaaca tactctaccc gtaccgcaaa ccgacacagg
       61 tagtcgaggc gagtagcctc aggtgagcga gagaactctc gttaaggaac tcggcaaaat
      121 gaccccgtaa cttcgggaga aggggtgctg actttaagtc agccgcagtg aataggccca
      181 agcaactgtt tatcaaaaac acagctctct gctaaatcgt aagatgatgt atagggggtg
      241 acgcctgccc ggtgctggaa ggttaagagg agtgcttagc gtaagcgaag gtatgaattg
      301 aagccccagt aaacggcggc cgtaactata acggtcctaa ggtagcgaaa ttccttgtcg
      361 ggtaagttcc gacccgcac
//
LOCUS       DAVLMQ010000166          347 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.167, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000166 DAVLMQ010000000
VERSION     DAVLMQ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.167"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            1..347
                     /locus_tag="VXF95_002277"
                     /pseudo
     CDS             1..347
                     /locus_tag="VXF95_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          102 a           77 c           60 g          108 t
ORIGIN      
        1 attactatgg atatgtttag cccttactat gacttggcta aacagcttcg ctttcaaatt
       61 tctaggctca ggctgaaaca gtctcctaga ctgtttcact cccgaatgct aaaatcgttc
      121 ttgatcgctt tcacattgta caacatctta gccgtgctat gagtcgtgtg cgtgtccaaa
      181 tcatgaatca gtttcatcga aaatcccatg aacacaaggc tatcaagcac tactggaagc
      241 tcatacaaca ggatagccgt aaactgagtg ataagcaatt ttatcgtcct acttttcgta
      301 tgcacttaac caataaagag attttaaaca agcttttgag ttattcg
//
LOCUS       DAVLMQ010000167          340 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.168, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000167 DAVLMQ010000000
VERSION     DAVLMQ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..340
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.168"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>340
                     /locus_tag="VXF95_002278"
     CDS             <1..>340
                     /locus_tag="VXF95_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HEV1082709.1"
                     /translation="IRDHFLKYDRAVRCRVKIITMDMFSPYYGLAKQLRFHIVQHLSR
                     AMSRVRVQIMNQFHRKSHEYKAIKRYWKLIQQDSRKLSDKQFYRPTFRMHLTNKEILN
                     KLLSYSEDLK"
BASE COUNT          104 a           71 c           61 g          104 t
ORIGIN      
        1 tcatccgaga tcactttctt aaatatgata gagccgtccg atgtcgcgtc aaaattatta
       61 ctatggatat gtttagccct tactatggct tggctaaaca gcttcgcttt cacattgtac
      121 aacatcttag ccgtgctatg agtcgtgtgc gtgtccaaat catgaatcag tttcatcgaa
      181 aatcccatga atacaaggct atcaagcgct actggaaact cattcaacag gatagccgta
      241 aactgagtga taagcaattt tatcgtccta cttttcgtat gcatttaacc aataaagaga
      301 ttttaaacaa gcttttgagc tattcggaag acttgaaaca
//
LOCUS       DAVLMQ010000168          328 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.169, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000168 DAVLMQ010000000
VERSION     DAVLMQ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..328
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.169"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            186..>328
                     /locus_tag="VXF95_002279"
     CDS             186..>328
                     /locus_tag="VXF95_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Blp family class II bacteriocin"
                     /protein_id="HEV1082710.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAILGGV
                     AYAA"
BASE COUNT          126 a           35 c           73 g           94 t
ORIGIN      
        1 tagtaaaaaa gtgattagaa aacatctttt ttaaaaatag agatgatttt gaaacaaaaa
       61 agctaattca agacgtttcg atgccaattc aagatttgga tgaaaaaaat taatagatac
      121 tgttatacta aacttgtcaa gtttgtaaca agacaaatat taaaaataaa aaagaggtat
      181 tcgttatgaa tacaaaaaag atgtcacaat ttgaaattat ggatactgag atgcttgctt
      241 gcgttgaagg tggcggatgc aattggggag attttgccaa agcaggtgtt ggaggaggag
      301 ctatacttgg aggtgtggcc tatgcagc
//
LOCUS       DAVLMQ010000169          295 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.170, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000169 DAVLMQ010000000
VERSION     DAVLMQ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 295)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 295)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..295
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.170"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..>295
                     /locus_tag="VXF95_002280"
     CDS             <1..>295
                     /locus_tag="VXF95_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001821980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082711.1"
                     /translation="GRNFWNVFNCFKHYLFRKNSETGVQSGPDYATLGMYKGSADWKY
                     ITFTYDYSEKTNFDQLKTSLRFNLEGATSGTAWVTGIKVEIGSVATDWSPAPE"
BASE COUNT           94 a           44 c           71 g           86 t
ORIGIN      
        1 aaggtcgaaa tttttggaat gtatttaatt gcttcaaaca ttatcttttt agaaaaaata
       61 gtgagaccgg agtacagagt ggtccagatt atgctacgct tggtatgtat aaaggttcgg
      121 cagattggaa atatattaca ttcacttatg actactctga aaaaacaaat tttgatcaat
      181 tgaagacatc attgcgattc aatcttgaag gtgctacaag cggtacagct tgggtaacag
      241 gaatcaaggt tgaaatcggt agtgtggcga cggactggag tcctgcgcct gagga
//
LOCUS       DAVLMQ010000170          266 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.171, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000170 DAVLMQ010000000
VERSION     DAVLMQ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.171"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>266)
                     /locus_tag="VXF95_002281"
     CDS             complement(<1..>266)
                     /locus_tag="VXF95_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HEV1082712.1"
                     /translation="EVVSYDDAAQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLH
                     DAKGNKIDRAPNPMELLTIKVPQPVQSGDMVRALKEGLINLYKE"
BASE COUNT           71 a           57 c           51 g           87 t
ORIGIN      
        1 tcttccttat aaagattgat gagtccttct tttaatgcac gaaccatgtc tcctgattga
       61 acgggttgag gcaccttaat agtcaatagt tccattggat ttggagcgcg gtcgatttta
      121 ttgcctttgg catcatgcaa atcttcaata taggtttcaa aatgacggaa acctggacca
      181 taaaactcaa cttggtcccc ttcgttaatg acatttcgtt gacgaatagt tgctgtttgt
      241 gccgcatcat cataagaaac cacttc
//
LOCUS       DAVLMQ010000171          263 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.172, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000171 DAVLMQ010000000
VERSION     DAVLMQ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.172"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..174
                     /locus_tag="VXF95_002282"
     CDS             <1..174
                     /locus_tag="VXF95_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HEV1082713.1"
                     /translation="NRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDTSSSGVTL
                     ITGKNGTGKSTLL"
BASE COUNT           89 a           32 c           45 g           97 t
ORIGIN      
        1 aacagaactg tttcttttgc tattagttca aaaggagaaa aaatgaaagt agaaaatatt
       61 tcgtataggg tggatcatcg tatattgttt gataatattt cttttgatac ttcgagttca
      121 ggcgtgacat taattactgg taaaaatggt acaggaaagt caactttact atagtagatt
      181 gaaactagaa tagtacacat ctacttctaa aatattgtta gaaattgatt tgactatcct
      241 gatctatttg tcctgttctt att
//
LOCUS       DAVLMQ010000172          257 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.denovo.173, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000172 DAVLMQ010000000
VERSION     DAVLMQ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 257)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 257)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..257
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.denovo.173"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            complement(<1..>257)
                     /locus_tag="VXF95_002283"
     CDS             complement(<1..>257)
                     /locus_tag="VXF95_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HEV1082714.1"
                     /translation="ANWGNNWNYAGPKAWNVNTDGKMYCRNEVGFYDQVDFSNSSRAN
                     FYGNTTFSRSPVFSNGIELGSKDVLGDGWNPKGGRNAVVWW"
BASE COUNT           77 a           73 c           36 g           71 t
ORIGIN      
        1 ccaccaaaca accgcattcc ttccgccttt gggattccaa ccatcaccaa gcacatcttt
       61 acttccaagt tcgataccat ttgaaaacac aggagaacga gaaaaagtag tattcccata
      121 gaagtttgct ctcgatgaat tcgaaaaatc cacttgatca taaaaaccga cttcattcct
      181 acagtacatt ttcccatcag tattgacgtt ccatgcttta ggtccggcat agttccaatt
      241 atttccccag ttcgccc
//
LOCUS       DAVLMQ010000173         6841 bp    DNA     linear   BCT 18-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain AUSMDU00073471
            SAMN33607499-rid17946403.guided.079, whole genome shotgun sequence.
ACCESSION   DAVLMQ010000173 DAVLMQ010000000
VERSION     DAVLMQ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN33607499
            Sequence Read Archive: SRR23725826
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-MAY-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-MAY-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001721703.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001721703.1
            Genome Coverage       :: 268x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 05/06/2023 23:33:09
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,293
            CDSs (total)                      :: 2,244
            Genes (coding)                    :: 2,107
            CDSs (with protein)               :: 2,107
            Genes (RNA)                       :: 49
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 1 (16S)
            partial rRNAs                     :: 1, 3 (5S, 23S)
            tRNAs                             :: 41
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 137
            CDSs (without protein)            :: 137
            Pseudo Genes (ambiguous residues) :: 0 of 137
            Pseudo Genes (frameshifted)       :: 73 of 137
            Pseudo Genes (incomplete)         :: 68 of 137
            Pseudo Genes (internal stop)      :: 32 of 137
            Pseudo Genes (multiple problems)  :: 34 of 137
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6841
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN33607499-rid17946403.guided.079"
                     /strain="AUSMDU00073471"
                     /serotype="23B1"
                     /host="Homo sapiens"
                     /db_xref="taxon:1313"
                     /country="Australia: Victoria"
                     /collection_date="2022"
                     /collected_by="MDU-PHL"
                     /note="genotype: ST1373"
     gene            <1..374
                     /locus_tag="VXF95_002284"
     CDS             <1..374
                     /locus_tag="VXF95_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082715.1"
                     /translation="PLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKIDAYVVNN
                     HEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVWHFLCHLD
                     PMFVEIEDVEGYVKEEVGEIQ"
     gene            696..884
                     /locus_tag="VXF95_002285"
     CDS             696..884
                     /locus_tag="VXF95_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HEV1082716.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            946..1704
                     /locus_tag="VXF95_002286"
     CDS             946..1704
                     /locus_tag="VXF95_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HEV1082717.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEAVLYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVVF"
     gene            1762..2223
                     /locus_tag="VXF95_002287"
     CDS             1762..2223
                     /locus_tag="VXF95_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1082718.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGIWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRF"
     gene            2257..2616
                     /locus_tag="VXF95_002288"
     CDS             2257..2616
                     /locus_tag="VXF95_002288"
                     /inference="COORDINATES: protein motif:HMM:NF015692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HEV1082719.1"
                     /translation="MNDNPIECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQET
                     VPQAIIAFLESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLD
                     EPLKDVVRRWENRIKVY"
     gene            2728..3612
                     /locus_tag="VXF95_002289"
     CDS             2728..3612
                     /locus_tag="VXF95_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HEV1082720.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLTNKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKQGILA
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVIANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            3775..5514
                     /locus_tag="VXF95_002290"
     CDS             3775..5514
                     /locus_tag="VXF95_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HEV1082721.1"
                     /translation="MELSAIYHRTESEYAYLYKDKKLHIRIRTKKGDIESINLHYGDP
                     FIFMEEFYQDTKEMVKITSGTLFDHWQVEVSVDFARIQYLFELRDTEGQNILYGDKGC
                     VENSLENLHAIGNGFKLPYLHEIDACKVPDWVSNTVWYQIFPERFANGNALLNPEGTL
                     DWDSSVTPKSDDFFGGDLQGIIDHMDYLQDLGITGLYLCPIFESTSNHKYNTTDYFEI
                     DRHFGDKETFRELVDQAHHRGMKVMLDAVFNHIGSQSLQWKNVVKNGEQSAYKDWFHI
                     QQFPVTTEKLVNKRDLPYHVFGFEDYMPKLNTANPEVKNYLLKVATYWIEEFNIDAWR
                     LDVANEIDHQFWKDFRKAVLAKNPDLYILGEVWHTSQPWLNGDEFHAVMNYPLSDSIK
                     DYFLRGIKKTDQFIDEINGESMYYKQQISEVMFNLLDSHDTERILWTANEDVQLVKSA
                     LAFLFLQKGTPCIYYGTELALTGGPDPDCRRCMPWERVSSDNDMLNFMKRLIKIRKYA
                     SVIISHGKYSLQEIKSDLVALEWKYEGRILKAIFNQSTEDYLLEKEAVALASNCQELE
                     NQLVISPDGFVIF"
     gene            5789..6091
                     /locus_tag="VXF95_002291"
     CDS             5789..6091
                     /locus_tag="VXF95_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082722.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNVIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKLVSINE"
     gene            6147..6575
                     /locus_tag="VXF95_002292"
     CDS             6147..6575
                     /locus_tag="VXF95_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HEV1082723.1"
                     /translation="MDGITKDFIKTAKLMKQLWPQLTDKEAIDEVKKYTNGKNTAIFT
                     EVEGDTIVGLALCSLRFDYVEGCKYSPVGFLEGIIVDEEYRLKDIAKNLCTKCEEWAK
                     NKGCKEFASDCTLTNTDSIRFHLNIGFQEANRIIHFKKKL"
     gene            6654..>6841
                     /locus_tag="VXF95_002293"
     CDS             6654..>6841
                     /locus_tag="VXF95_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HEV1082724.1"
                     /translation="MGGNPPMKKYSIVDKIVLSTKIKRIIIFTVFRENWEPYMKKYTE
                     VFQSQFPNLNIDYLLLDT"
BASE COUNT         2333 a          990 c         1429 g         2089 t
ORIGIN      
        1 ttcctttatc taaatttatg ttcgatcctg aggaaaatgt aaacattatt tggaaagaga
       61 tttcaaattt atccctcaaa aatgatagag tgatcgaagg atattcaaaa attgatgcat
      121 atgtcgttaa caaccatgaa gttaaagcct atgtcgaaac aagagaaacg aactatcgta
      181 aagcaaaaga cttcttagaa agccgcggat atgaaatcga cagaagcttt ttcggaagtg
      241 aagacggtga agcgattctt tacagaaaaa aagggatcga agtttggcat ttcttgtgtc
      301 acttagaccc aatgtttgta gagattgaag atgtagaagg atatgttaaa gaagaagttg
      361 gagagattca atagtcaacc aaagttcctt gtgagtatat acctttgcta gtaaaagagt
      421 caaaacgtta taacgaaggg ggggaagaaa acccttgagt gtaagtcttt ttcttgttta
      481 gagggaaagt attagagtag ccgctcataa tttatactag atttgataac tgatttgaga
      541 cagattttat ttctataaat attgtgaaaa ttttttaata ccaaagattt aaagttactg
      601 tgttaaaaat cctctccact tttaaactaa tgtattataa aagccagttg acacaagtgt
      661 tacacctgtg atagaattaa cttgaggtga tgaaaatggc aaccgataaa aatagaataa
      721 tgattagctt ggatgataaa aatctagaga aacttgaaaa tttagtagaa gatgctagag
      781 atagaagggg aatgcgacta acaaagtccc aggttattga attactccta aataccgttg
      841 attatttcga tgatattatg ggggctattt actcaaaaaa ataagagcaa aattgctatt
      901 attttttaca aattggtgta acactagtga tataggagtg atgaaatggt tgtttatatt
      961 agacaaagta aattaccaag tgaggtttca attaataaat acaatgctca agtaggtgcc
     1021 tacttacaag gagaagaagc tgttttatat caatcttttt ctgaaataaa agagttaaca
     1081 agtgaagata tagttgtaga ttatataatg gagactagag cattactaaa aatgatgggc
     1141 ttaaacgttc cggttcatga ctatcctatt gagcttaaag agttttatgg tcgaaagatt
     1201 tatgctggta ttttaggaga gattgtgaat atacctgata attggggaaa atttattaag
     1261 cctaaagctg gttcaaaagt ctttactgga agagttgtta atggaaccca tgatttaata
     1321 ggtattggtc tacctttcga ctatcctata tggattagtg aggttgtaga attcatagct
     1381 gaatggcgtt gttttgtgtt agatggtcgc gtattagatg ttcgacccta tacaggtgat
     1441 tatcatgcac aatttgatgc aagtgtaatt gatgaagcga tatcatgttg gaaagatgcg
     1501 ccaatagctt atggactaga tatcggtgtt actcgcgatg gcagaacact tgttgttgaa
     1561 gtaaatgatg gttatgcatt gggaaattat ggcctatctc ctttaaaatc aatcaatttt
     1621 catagagcta ggtggaaaga aatggtaaaa ccctattttg aaaaaaatga aatttttaaa
     1681 atccaacagg atgttgtttt ctaaaataaa tatggtatat aaccaatata aaaagcatca
     1741 aaatgaacaa ggaggaatct gatgcttgga gcaattattg gagatattgt cggttctgtt
     1801 tacgaatgga acaatatcaa aacaaaggac tttcctttat ttcggaagga ctgctttttt
     1861 acagatgaca cggttatgac ctgtgctgtt gcagaagcaa ttatgaatgg tggacaaaaa
     1921 gacgacttca ttgacgcgat gaagaaatat ggcagaatgt atccgaatgc tgattacggt
     1981 gctcggttta atgcatggct aaacagcgat aaccgtgagc cttataatag ctttgggaat
     2041 ggatcagcta tgcgtatttc tccatgtgct tggatcatgg actgtggttt ttatgcgaaa
     2101 actggtatat ggccatcatc tagaggactt acgagtcttt ctgcagaggt aactcataat
     2161 catccagaag gtgtcaaagg cgctatggct acagctgatg ctatctttct atgtcgtttt
     2221 taatttggtg gttattgtag agagtacgag taatcaatta acgacaatcc tatagagtgt
     2281 aaaagacgaa ttaaggatta tatagaaaaa gaatacgatt acaatctatc tcaaacttta
     2341 gatgaaatcc gtcctaacta tcgttttaac gaaacatgtc aggaaactgt ccctcaagcc
     2401 attatcgcct ttcttgaaag tagagacttc gaagatgcga taagaaatgc catctcactt
     2461 ggtggcgaca gtgatactct cgcagcaatc acttgtagca tagcagaggc agcttacggt
     2521 attcctgatt ggatcaagga taaggcctat tcttacttgg atgaaccctt aaaggatgta
     2581 gttaggcgat gggaaaatag aataaaagtg tattaatctc cagtacgtca gatttctctt
     2641 ttctgtattt tcattgtata ataggattac atttacttgc atacgacgaa atgtaaacat
     2701 ttctatttaa aattaaggat aaaatcaatg aaaaaagcaa tggtaattat caaccctact
     2761 tctggtggcg agaaggcttt ggattacaaa gaaaagctgg agaataaagc aaaagaatac
     2821 tttgaatatg ttgaaaccaa aattaccgaa aaagcgctgg atgcaacaca ttttgctgaa
     2881 gaagcttctc gtgagcagta tgatgcagtg gttgtgtttg gtggagatgg gactgtcaat
     2941 gaagtcattt caggtattga tgagagagac tacattccta agttagggat tatcccaggc
     3001 ggtacgggta acctcattac aaaacttttg gaaatcaatc aagacatcga tggcgcaatt
     3061 gacgaactgg attttgattt aaccaataag attgatatcg gtaaagcaaa tgacaactat
     3121 tttggttata tctttagtat cggttctctg cctgaggcga ttcacaatgt tgaaatagag
     3181 gacaaaacaa aacaaggtat tttagcctat gctgtaaata ctatgaagtc tgtcatgaca
     3241 gatcaggtct ttaacattaa ggttgagaca gaaaatggaa attatgttgg tgaagctagc
     3301 catgttttgg tccttttgac aaattacttc gctgataaga aaatctttga agaaaacaag
     3361 gacggctatg ccaacatttt gattctgaaa gatgcctcta tattctccaa attatccgtc
     3421 attcctgatt tattaaaagg ggatgttatc gcaaatgata atatcgagta tatcaaagcg
     3481 cgtaatatta aaatctcttc agatagtgaa ttggagtcag atgttgacgg agataaatca
     3541 gataacctac ctgtagaaat caaagtccta gctcagcgag tagaagtatt ttcaaaaccg
     3601 aaagaggatt agtatataga gaaagccttt tttaaggctt tttgtatact ttaaaagata
     3661 gttcctttaa caacggacat tccttgcaaa tagttcacaa aaatagtata ctggattcat
     3721 tgagtttgaa aacgtttgcg taaaatttga atgaatactt taggagataa attgatggaa
     3781 ttgagtgcta tttaccatag gactgagtcg gagtatgcct atctttataa ggataagaaa
     3841 ctccatattc gaattcgaac taagaaaggg gacattgaaa gcatcaactt gcactatggg
     3901 gaccctttta tctttatgga ggagttttat caggatacaa aagaaatggt caagataact
     3961 tctggtacct tatttgacca ttggcaggtt gaagtgtcag ttgactttgc acgtatccag
     4021 tatctttttg agctcagaga tacagaaggt caaaatattt tgtatggcga taaagggtgt
     4081 gtggaaaatt ctctagaaaa tcttcatgca attgggaatg gatttaagtt gccttatctt
     4141 catgagattg atgcctgcaa ggttcctgac tgggtttcaa atacggtatg gtatcagata
     4201 tttcctgaaa gatttgccaa tggcaatgct ctattaaacc cagaagggac tttagactgg
     4261 gattcatctg tcacacctaa gagcgatgat ttctttggtg gtgatttaca ggggattatt
     4321 gatcatatgg attacttgca agacttgggt attactggac tatatctttg tcccatcttt
     4381 gaatctacaa gcaatcacaa gtacaatacg acagattact ttgaaattga ccgtcatttt
     4441 ggagacaagg agacctttcg ggaactggtg gatcaagcgc atcatcgtgg catgaaagtc
     4501 atgctggatg cggtatttaa tcatattggt tcgcaatctc ttcaatggaa aaatgtcgtc
     4561 aaaaatggtg aacagtctgc ttataaggat tggttccata ttcaacaatt cccagtgaca
     4621 actgaaaagc tagttaataa gagagactta ccctatcatg tttttggttt cgaggactat
     4681 atgcctaagc taaatacagc caatccagag gtcaagaatt atcttttaaa ggttgcgact
     4741 tattggattg aagagtttaa tatcgatgct tggcgtttgg atgtggctaa tgagattgac
     4801 catcagttct ggaaggattt tcgtaaggca gttttagcta aaaatcctga tctttatatc
     4861 ctaggagaag tctggcatac atctcagcct tggctaaatg gagatgagtt ccatgccgtc
     4921 atgaattatc ctttatctga tagtatcaag gactatttct tacgaggaat taagaagaca
     4981 gaccagttca tcgatgaaat caatggagag tctatgtatt acaagcagca gatttcagag
     5041 gtcatgttta atctcttgga ttcacatgat acagagcgaa tcctgtggac ggccaatgaa
     5101 gatgttcaac tggttaaatc agccttagcc tttctctttt tacaaaaagg aacaccgtgc
     5161 atttattacg gaaccgagct agccttgact ggaggaccag atccagattg tcgtcgttgt
     5221 atgccttggg aacgtgtatc aagtgacaat gatatgctga actttatgaa gaggctgatt
     5281 aagattcgga aatacgcgtc agtaatcatt tcgcatggca agtatagcct tcaagaaatc
     5341 aaatctgatc tagtagctct ggaatggaaa tacgaaggac ggatcctcaa agcaatattc
     5401 aaccaatcaa cagaagatta tcttttagag aaagaagcag tagcactagc aagcaattgc
     5461 caagaattgg agaatcagct tgtcatctct ccagatggat ttgtgatttt ctaaaaacta
     5521 gttgatgaag attatggtac atttcatatc ttatatagta taataaggct agttactaaa
     5581 cttgtaaagg agaacttaaa tgaattgtag aggacacgaa acaagacaaa gaattgttag
     5641 agattttgaa gtttagccta aagcacatat taagctgtta gcaaatcaac aaaaacatag
     5701 tgatgcagga gcaactattg aagatgaata ttatgtattt atcgctgaga gtaaaattga
     5761 tggcaagaag gaagttattc agtgttgcat gggtgcggca agggattttt tagaactaat
     5821 taatcacaaa gggctacctc tttttaatcc gcttgtaggt gattctcatg taaataatag
     5881 acaagaatat gacaatacag ggagtggaaa tttacaacct gaaaagtgga atgaaactgc
     5941 aaagcagctt tataatgtta taatgtggtt gattatttta tggaatgcta agccggatac
     6001 acctttattt aattttaaag acgaagtaat taagtataaa acatatgagc cttttgaaag
     6061 cagtataaaa ttggtatcaa tcaatgagta acaaagtatc agcatgattc gaaacattta
     6121 cttgtaattt gcggaggaac atcaatatgg atggaataac aaaagatttt ataaaaacgg
     6181 ctaaactaat gaaacaatta tggccccaat tgaccgataa agaagctatt gatgaagtaa
     6241 aaaaatatac gaatggcaaa aatactgcaa tctttactga agttgaaggt gacacaattg
     6301 taggtctagc actatgttca ctcagatttg attatgttga aggttgtaaa tatagtcctg
     6361 ttggattctt agaagggatt attgttgacg aggaatatcg tttaaaggat attgctaaaa
     6421 atctctgtac aaaatgtgag gaatgggcga aaaataaagg atgtaaggaa tttgcaagtg
     6481 actgtacttt aacgaatacg gattctataa gatttcatct caatattgga tttcaggagg
     6541 caaatagaat tattcatttt aagaaaaaat tataatttag aaacgtgaat aaacttgttt
     6601 aaactttatg tatctttaga aagtgtgtta acttgaaaga acaaattttt ttgatgggtg
     6661 ggaatccccc aatgaagaaa tatagtattg ttgataaaat tgtattatca accaagatta
     6721 aaagaattat catttttaca gtttttcgag aaaattggga accgtacatg aaaaagtaca
     6781 cggaagtttt tcaaagtcaa tttcctaatc taaacattga ttacttgctc ctggacactg
     6841 a
//
